CN104224246A - ASD (atrial septal defect) reserved-hole occluder - Google Patents
ASD (atrial septal defect) reserved-hole occluder Download PDFInfo
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- CN104224246A CN104224246A CN201410187151.2A CN201410187151A CN104224246A CN 104224246 A CN104224246 A CN 104224246A CN 201410187151 A CN201410187151 A CN 201410187151A CN 104224246 A CN104224246 A CN 104224246A
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- 208000035478 Interatrial communication Diseases 0.000 title claims abstract description 29
- 206010003664 atrial septal defect Diseases 0.000 title claims abstract description 29
- 208000013914 atrial heart septal defect Diseases 0.000 title claims abstract description 24
- 229910001285 shape-memory alloy Inorganic materials 0.000 claims abstract description 34
- 230000000903 blocking effect Effects 0.000 claims description 24
- 229910045601 alloy Inorganic materials 0.000 claims description 15
- 239000000956 alloy Substances 0.000 claims description 15
- 238000007789 sealing Methods 0.000 claims description 3
- 210000001147 pulmonary artery Anatomy 0.000 abstract description 6
- 206010016803 Fluid overload Diseases 0.000 abstract description 3
- 210000000709 aorta Anatomy 0.000 abstract description 2
- 230000004888 barrier function Effects 0.000 abstract 5
- 206010064911 Pulmonary arterial hypertension Diseases 0.000 abstract 1
- 238000009954 braiding Methods 0.000 abstract 1
- 230000000149 penetrating effect Effects 0.000 abstract 1
- 230000000452 restraining effect Effects 0.000 abstract 1
- 208000002815 pulmonary hypertension Diseases 0.000 description 9
- 230000007547 defect Effects 0.000 description 6
- 230000017531 blood circulation Effects 0.000 description 4
- 208000002330 Congenital Heart Defects Diseases 0.000 description 3
- 208000028831 congenital heart disease Diseases 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000002685 pulmonary effect Effects 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 230000002792 vascular Effects 0.000 description 3
- 206010008469 Chest discomfort Diseases 0.000 description 2
- 206010027336 Menstruation delayed Diseases 0.000 description 2
- 206010039163 Right ventricular failure Diseases 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 230000004872 arterial blood pressure Effects 0.000 description 2
- 230000006837 decompression Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000005246 left atrium Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 206010007559 Cardiac failure congestive Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010061818 Disease progression Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 206010042434 Sudden death Diseases 0.000 description 1
- 238000002583 angiography Methods 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- GJPICJJJRGTNOD-UHFFFAOYSA-N bosentan Chemical compound COC1=CC=CC=C1OC(C(=NC(=N1)C=2N=CC=CN=2)OCCO)=C1NS(=O)(=O)C1=CC=C(C(C)(C)C)C=C1 GJPICJJJRGTNOD-UHFFFAOYSA-N 0.000 description 1
- 229960003065 bosentan Drugs 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000005750 disease progression Effects 0.000 description 1
- 230000013020 embryo development Effects 0.000 description 1
- 230000005713 exacerbation Effects 0.000 description 1
- 210000003191 femoral vein Anatomy 0.000 description 1
- 210000002837 heart atrium Anatomy 0.000 description 1
- 230000000004 hemodynamic effect Effects 0.000 description 1
- 210000004971 interatrial septum Anatomy 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 230000036244 malformation Effects 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 230000007334 memory performance Effects 0.000 description 1
- 238000002324 minimally invasive surgery Methods 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 210000005245 right atrium Anatomy 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000002861 ventricular Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00606—Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00646—Type of implements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Abstract
The invention discloses an ASD (atrial septal defect) reserved-hole occluder comprising a left disc, a right disc, a cylindrical barrier portion and through hole penetrating the left disc, the right disc and a cylindrical. The left disc and the right disc are used for occluding an opening. The cylindrical barrier portion between the left disc and the right disc occludes the ASD. The diameter of the left disc is greater than that of the right disc. The diameter of the right disc is greater than that of the cylindrical barrier portion. The left disc, the right disc, the cylindrical barrier portion and the through hole are all made by braiding a plurality of memory alloy wires; the memory alloy wires penetrate the through hole to form a wall of the through hole and are wound into the left disc, the right disc and the cylindrical barrier portion; two ends of every memory alloy wire are both fixed to a same fixture used for restraining the memory alloy wires; the memory alloy wires are mutually staggered into an elastic mesh; a seal film is arranged in the elastic mesh. Branch flows of the aorta and pulmonary arteries are limited, volume overload and pressure conduction of pulmonary vessels are relieved, a release space is provided for high pressure of the right heart system, and patients with advanced pulmonary arterial hypertension are saved.
Description
Technical field
Patent of the present invention relates to technical field of medical instruments, is specifically related to a kind of atrial septal defect plugging device for the treatment of congenital heart disease.
Background technology
Atrial septal defect (Atrial septal defect, ASD) is a kind of common congenital heart disease, is that original interatrial septum occurs abnormal in embryo development procedure, causes between left and right atrium and leave over hole.Atrial septal defect can occur separately, and also can deposit with the cardiovascular malformation of other types, women is common, the ratio of men and women is about 1:3.Because atrium level exists shunting, corresponding abnormal hemodynamics can be caused.The child of most Transcatheter Closure of Secundum can be asymptomatic except easily catching a cold and waiting respiratory tract infection, and activity is also unrestricted, generally just shows out of breath, cardiopalmus, weak etc. to nonage.Most humans exacerbation of symptoms after 40 years old, and often there is pulmonary hypertension, arrhythmia and congestive heart failure, the former is dead major reason.Early stage ASD, surgical operation or the operation of Wicresoft transcatheter can both radical curing of disease, can will completely lose to opportunity of operation when there is the severe pulmonary hypertension stage by disease progression.Even if because now close atrial septal defect, pulmonary hypertension also can not reduce, and rising even further occurs cardiovascular malignant event.Pulmonary hypertension can not be cured, and is called " cancer in cardiovascular diseases ", one after diagnosing after median survival interval be only 2 ~ 3 years, and serious symptom person prognosis is poorer.Domestic and international multicenter study explores targeted drug treatment, to a certain degree can improve patients symptomatic, but the existence time limit is without change, targeted drug somewhat expensive in addition, (as Wan Tawei every month 50,000 yuan, bosentan every month 30,000 yuan) life-time service is also unrealistic.
The irreversible change of congenital heart disease a large amount of left to right shunt Pulmonary Vascular, closes defect by force and right ventricular pressure can be caused to discharge nowhere, occur right heart failure and sudden death, but the existence letting alone defect can make again the state of an illness worsen further.
Summary of the invention
For the deficiency existed in background technology, the object of the present invention is to provide a kind of atrial septal defect of Minimally Invasive Surgery to box out stopper, merging the death time of severe pulmonary hypertension patient for postponing ASD, reduction of patient clinical symptoms.
For achieving the above object, the atrial septal defect of the present invention's design is boxed out stopper, it is characterized in that: comprise the left dish of sealing gap and right dish, between left dish and right dish, block the column blocking part of atrial septal defect, and run through the through hole of above-mentioned left dish, right dish and column blocking part; The diameter of described left dish is greater than the diameter of described right dish, and the diameter of described right dish is greater than the diameter of described column blocking part; Described left dish, right dish, column blocking part and described through hole are all worked out by many memory alloy wires to be formed; Described memory alloy wire forms the hole wall of described through hole through described through hole, and coiling forms described left dish, right dish and described column blocking part, and the two ends of described memory alloy wire are all be fixed on the same stationary fixture of the described memory alloy wire of constraint; Many described memory alloy wires intermesh into elastic network(s), are provided with diaphragm seal in described elastic network(s).
Further, described stationary fixture comprises the joint coaxial and unsettled with described through hole, and the sidewall of described joint connects at least one alloy connection strap; The two ends of described memory alloy wire are fixed on described alloy connection strap.
Further, the external diameter of described joint is less than the diameter of described through hole.
Again further, the span of the external diameter of described joint is 1-3 millimeter.
Preferably, the sidewall of described joint connects three connection straps, and the angle between adjacent described connection strap is 120 °; The two ends of described memory alloy wire are fixed on described connection strap.
Further, the diameter of described through hole is 3-6 millimeter.
The invention has the beneficial effects as follows: relative to existing stopper, invention increases a through hole, not only limit most aorta-Pulmonic shunting like this, large defect is become less defect, both the aortic flow having limited high pressure chest flows to pulmonary artery, alleviates pulmonary vascular volume overload and pressure passes to; Pulmonary artery pressure can be prevented again to raise suddenly simultaneously and cause serious consequence.So, when Pulmonic pressure exceedes aortal pressure, blood flow can by reserved aperture shunting decompression, and the height making the right side feel concerned about system is pressed with the space of release, saves patients with pulmonary hypertension in late period.So, make the treatment of incorrigible whole ASD merging in latter stage severe pulmonary hypertension become possibility first; The unsettled joint of the right card of stopper can connect conveying wirerope easily, the release of the control stopper of safety; Stopper central authorities box out, and solve pulmonary hypertension continuation rising after in the past installing stopper and cause this complication of right heart failure; Limit most of aorta and flow to Pulmonic blood, cured disease from cause of disease aspect, make the state of an illness not in progress.
Accompanying drawing explanation
Structural representation when Fig. 1 is of the present invention opening,
Fig. 2 is that schematic diagram is looked on a left side of Fig. 1,
Fig. 3 is that schematic diagram is looked on the right side of Fig. 1;
Fig. 4 is the schematic diagram that the present invention discharges completely;
Fig. 5 is a kind of embodiment of stationary fixture of the present invention;
Fig. 6 is perspective view of the present invention, and wherein diaphragm seal is not shown,
Fig. 7 is the structural representation of the present invention's wherein two memory alloy wire coilings.
In figure: left dish 1, right dish 2, blocking part 3, through hole 4, memory alloy wire 5, stationary fixture 6, delivery sheath 7, conveying wirerope 8;
Wherein: joint 5.1, alloy connection strap 5.2.
In Fig. 1, in order to represent through hole disclosed by the invention, therefore specially the memory alloy wire that through hole goes out is concealed, to reach better understanding effect; And in Fig. 4, be then the structure in order to express after the present invention's release, so not shown through hole.
Detailed description of the invention
As shown in Figure 1 to Figure 3, the atrial septal defect of the present invention's design is boxed out stopper, comprise the left dish 1 of sealing gap and right dish 2, between left dish 1 and right dish 2, block the column blocking part 3 of atrial septal defect, and run through the through hole 4 of above-mentioned left dish 1, right dish 2 and column blocking part 3; The diameter of described left dish 1 is greater than the diameter of described right dish 2, and the diameter of described right left dish 2 is greater than the diameter of described blocking part 3; Described left dish 1, right dish 2 and column blocking part 3 are the elastic network(s)s be compiled into by many memory alloy wires 5, are provided with diaphragm seal in described elastic network(s); Described memory alloy wire 5 one end is passed described through hole 4 and is formed the hole wall of described through hole 4, other end coiling forms the outline of described left dish 1, right dish 2 and described column blocking part 2, and the two ends of described memory alloy wire 5 be all be fixed on retrain described memory alloy wire 5 same stationary fixture 6 on.Like this, described in every root, memory alloy wire 5 one end is fixed on stationary fixture 6, the other end passes from through hole 4 and wraparound is fixed on stationary fixture 6, and described memory alloy wire 5 intersection is compiled into elastic network(s), and the elastic network(s) of described establishment molding not only forms left dish 1, right dish 2 and column blocking part 3, and the space defined for placing diaphragm seal, forms the hole wall of described through hole 4 simultaneously.Utilize the through hole 4 arranged that large defect is become less defect, the aortic flow both having limited high pressure chest flows to pulmonary artery, alleviates pulmonary vascular volume overload and pressure passes to; Pulmonary artery pressure can be prevented again to raise suddenly simultaneously and cause serious consequence.So, when Pulmonic pressure exceedes aortal pressure, blood flow can by reserved through hole 4 shunting decompression, and the height making the right side feel concerned about system is pressed with the space of release, saves patients with pulmonary hypertension in late period.
Again as shown in Figure 3, a kind of embodiment how retraining memory alloy wire 5 end of the present invention is given: stationary fixture 6 comprises the joint 6.1 coaxial and unsettled with described through hole 4 in figure, the sidewall of described joint 6.1 connects three alloy connection straps 6.2, and the angle between adjacent described alloy connection strap 6.2 is 120 °; The two ends of described memory alloy wire 5 are fixed on described alloy connection strap 6.2.Like this, by the carrying of alloy connection strap 6.2, such that joint 6.1 is unsettled is arranged on through hole 4 place, and preferably, the external diameter of described joint 6.2 is less than the diameter of described through hole 4.Certainly, the quantity of alloy connection strap 6.2 and arrangement can have a variety of, but have such alloy connection strap 6.2 support bearing joint 6.1 at least, and the stopper that the present invention is designed can be admitted in human body.
Usually, the diameter of described through hole 6 is 3-6 millimeter.The span of the external diameter of joint 6.2 is 1-3 millimeter.
Use procedure of the present invention is summarized as follows: the joint 6.1 of the stopper of the present invention's design in delivery sheath 7 is connected with conveying wirerope 8, arrives heart, under X-ray, angiography etc. coordinate, directly send to and fall left atrium along the femoral vein established; Open left dish 1, pull back conveying wirerope 8 and delivery sheath 7, left dish 1 is tightly fitted with side, ASD left room; Then, slowly open column blocking part 3, Synchronous shutoff position all normal after slowly open right dish 2 again, left dish 1 and right dish 2 are clipped in the both sides of atrial septal defect by self super-elasticity and memory performance; Finally, check that plugging effect is good, break connector 6.2 and the connection of carrying wirerope 8, as shown in Figure 4.
The external diameter of joint 6.1 disclosed in the present invention is less than the diameter of through hole 4, and such benefit is, joint 6.1 can be in same plane with the joint face of alloy connection strap 6.2 with alloy connection strap 6.2, and does not affect blood flow and pass through from through hole 4.When the external diameter of joint 6.1 is greater than the diameter of through hole 4, so just need alloy connection strap 6.2 along outwardly one section 6.21, the axis of column blocking part 3, thus eliminate joint 6.1 to the impact of blood flow by through hole 4, as shown in Figure 5.
In Fig. 5, union joint 6.1 goes out to be threaded with the junction of delivery sheath 7, and the screwed hole of union joint 6.1 is blind hole, and this screwed hole also can be through hole certainly; No matter be that blind hole or through hole all do not form impact to core idea of the present invention.
As shown in Figure 6 and Figure 7, to memory alloy wire 5 of the present invention, how coiling forms described through hole 4 and described left dish 1, right dish 2 and described column blocking part 3 are described, for convenience of explanation a described memory alloy wire 5 is divided into: the Part I 5.1 forming described through hole 4 hole wall, described hole wall is also netted, form the Part II 5.2 of left dish 1 end profile, form the Part III 5.3 of left dish 1 waist profile, form the Part IV 5.4 of left dish 1 and column blocking part 3 joint face profile, form the Part V 5.5 of column blocking part 3 waist profile, form the Part VI 5.6 of column blocking part 3 and right dish 2 joint face profile, form the Part VII 5.7 of right dish 2 waist profile, and form the Part VIII 5.8 of round table-like blocking part 3 end profile.Wherein, Part VIII 5.8 is the places, junction by the two ends of described memory alloy wire 5 and described alloy connection strap 6.2.Diaphragm seal is provided with in the space of " Contraband " shape of described memory alloy wire 5 formation.
Claims (6)
1. atrial septal defect is boxed out stopper, it is characterized in that: comprise the left dish of sealing gap and right dish, between left dish and right dish, block the column blocking part of atrial septal defect, and run through the through hole of above-mentioned left dish, right dish and column blocking part; The diameter of described left dish is greater than the diameter of described right dish, and the diameter of described right dish is greater than the diameter of described column blocking part; Described left dish, right dish, described column blocking part and described through hole are all worked out by many memory alloy wires to be formed; Described memory alloy wire forms the hole wall of described through hole through described through hole, and coiling forms described left dish, right dish and described column blocking part, and the two ends of described memory alloy wire are all be fixed on the same stationary fixture of the described memory alloy wire of constraint; Many described memory alloy wires intermesh into elastic network(s), are provided with diaphragm seal in described elastic network(s).
2. atrial septal defect according to claim 1 is boxed out stopper, and it is characterized in that: described stationary fixture comprises the joint coaxial and unsettled with described through hole, the sidewall of described joint connects at least one alloy connection strap; The two ends of described memory alloy wire are fixed on described alloy connection strap.
3. atrial septal defect according to claim 2 is boxed out stopper, it is characterized in that: the external diameter of described joint is less than the diameter of described through hole.
4. the atrial septal defect according to Claims 2 or 3 is boxed out stopper, it is characterized in that: the span of the external diameter of described joint is 1-3 millimeter.
5. atrial septal defect according to claim 2 is boxed out stopper, it is characterized in that: the sidewall of described joint connects three connection straps, and the angle between adjacent described connection strap is 120 °; The two ends of described memory alloy wire are fixed on described connection strap.
6. atrial septal defect according to claim 1 is boxed out stopper, it is characterized in that: the diameter of described through hole is 3-6 millimeter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410187151.2A CN104224246B (en) | 2014-05-05 | 2014-05-05 | ASD (atrial septal defect) reserved-hole occluder |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410187151.2A CN104224246B (en) | 2014-05-05 | 2014-05-05 | ASD (atrial septal defect) reserved-hole occluder |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104224246A true CN104224246A (en) | 2014-12-24 |
| CN104224246B CN104224246B (en) | 2017-04-12 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410187151.2A Active CN104224246B (en) | 2014-05-05 | 2014-05-05 | ASD (atrial septal defect) reserved-hole occluder |
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| Country | Link |
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| CN (1) | CN104224246B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107174386A (en) * | 2017-04-27 | 2017-09-19 | 广州启骏生物科技有限公司 | A kind of device for treating pulmonary hypertension |
| CN109077759A (en) * | 2018-10-23 | 2018-12-25 | 昆明市延安医院 | A kind of porous atrial septal defect plugging device |
| CN109925096A (en) * | 2019-04-29 | 2019-06-25 | 上海方维医疗科技有限公司 | For reducing the device of annulus of mitral valve opening area |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2613248Y (en) * | 2003-03-21 | 2004-04-28 | 龚善石 | Ventricular septel defect block device |
| CN1742689A (en) * | 2004-08-31 | 2006-03-08 | 解启莲 | Unidirectional valve heart septal defect plugger |
| WO2008040555A2 (en) * | 2006-10-05 | 2008-04-10 | PFM PRODUKTE FüR DIE MEDIZIN AKTIENGESELLSCHAFT | Implantable device |
| US20090187214A1 (en) * | 2008-01-18 | 2009-07-23 | Aga Medical Corporation | Percutaneous catheter directed intravascular occlusion device |
| CN201905941U (en) * | 2010-12-24 | 2011-07-27 | 王广义 | Atrial septal defect occluder |
| CN202776633U (en) * | 2012-07-30 | 2013-03-13 | 上海形状记忆合金材料有限公司 | Heart occluder |
-
2014
- 2014-05-05 CN CN201410187151.2A patent/CN104224246B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2613248Y (en) * | 2003-03-21 | 2004-04-28 | 龚善石 | Ventricular septel defect block device |
| CN1742689A (en) * | 2004-08-31 | 2006-03-08 | 解启莲 | Unidirectional valve heart septal defect plugger |
| WO2008040555A2 (en) * | 2006-10-05 | 2008-04-10 | PFM PRODUKTE FüR DIE MEDIZIN AKTIENGESELLSCHAFT | Implantable device |
| US20090187214A1 (en) * | 2008-01-18 | 2009-07-23 | Aga Medical Corporation | Percutaneous catheter directed intravascular occlusion device |
| CN201905941U (en) * | 2010-12-24 | 2011-07-27 | 王广义 | Atrial septal defect occluder |
| CN202776633U (en) * | 2012-07-30 | 2013-03-13 | 上海形状记忆合金材料有限公司 | Heart occluder |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107174386A (en) * | 2017-04-27 | 2017-09-19 | 广州启骏生物科技有限公司 | A kind of device for treating pulmonary hypertension |
| CN109077759A (en) * | 2018-10-23 | 2018-12-25 | 昆明市延安医院 | A kind of porous atrial septal defect plugging device |
| CN109077759B (en) * | 2018-10-23 | 2024-03-26 | 昆明市延安医院 | Porous atrial septal defect plugging device |
| CN109925096A (en) * | 2019-04-29 | 2019-06-25 | 上海方维医疗科技有限公司 | For reducing the device of annulus of mitral valve opening area |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104224246B (en) | 2017-04-12 |
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Effective date of registration: 20180815 Address after: 430070 202 building, No. 2, No. 2, B9 building, 818 hi-tech Avenue, East Lake New Technology Development Zone, Wuhan, Hubei. Patentee after: Wuhan Wei Ke Medical Technology Co., Ltd. Address before: 430022 753 Jing Han Road, Wuhan, Hubei Patentee before: Shang Xiaoke |