CN104205106A - 确定胎儿染色体非整倍性的方法、系统和计算机可读介质 - Google Patents

确定胎儿染色体非整倍性的方法、系统和计算机可读介质 Download PDF

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Publication number
CN104205106A
CN104205106A CN201380006955.1A CN201380006955A CN104205106A CN 104205106 A CN104205106 A CN 104205106A CN 201380006955 A CN201380006955 A CN 201380006955A CN 104205106 A CN104205106 A CN 104205106A
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China
Prior art keywords
chromosome
relative comparison
predetermined
internal reference
comparison rate
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Pending
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CN201380006955.1A
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English (en)
Chinese (zh)
Inventor
潘小瑜
陈盛培
曾玺
李旭超
张春雷
郭靖
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BGI Shenzhen Co Ltd
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BGI Shenzhen Co Ltd
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Publication of CN104205106A publication Critical patent/CN104205106A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201380006955.1A 2013-03-28 2013-03-28 确定胎儿染色体非整倍性的方法、系统和计算机可读介质 Pending CN104205106A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2013/073373 WO2014153755A1 (fr) 2013-03-28 2013-03-28 Procédé, système et support pouvant être lu par ordinateur pour déterminer une aneuploïdie de chromosome d'un foetus

Publications (1)

Publication Number Publication Date
CN104205106A true CN104205106A (zh) 2014-12-10

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ID=51622391

Family Applications (1)

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CN201380006955.1A Pending CN104205106A (zh) 2013-03-28 2013-03-28 确定胎儿染色体非整倍性的方法、系统和计算机可读介质

Country Status (2)

Country Link
CN (1) CN104205106A (fr)
WO (1) WO2014153755A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111226281A (zh) * 2019-12-31 2020-06-02 深圳华大临床检验中心 确定染色体非整倍性、构建分类模型的方法和装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101851626A (zh) * 2009-03-31 2010-10-06 王志钢 绒山羊4E-BP1基因cDNA编码区核苷酸序列
WO2012019323A1 (fr) * 2010-08-13 2012-02-16 深圳华大基因科技有限公司 Procédé d'analyse des chromosomes d'une cellule
CN102409088A (zh) * 2011-09-22 2012-04-11 郭奇伟 一种基因拷贝数变异的检测方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101851626A (zh) * 2009-03-31 2010-10-06 王志钢 绒山羊4E-BP1基因cDNA编码区核苷酸序列
WO2012019323A1 (fr) * 2010-08-13 2012-02-16 深圳华大基因科技有限公司 Procédé d'analyse des chromosomes d'une cellule
CN102409088A (zh) * 2011-09-22 2012-04-11 郭奇伟 一种基因拷贝数变异的检测方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TZE KIN LAU等: "noninvasive prenatal diagnosis of common fetal chromosomal aneuploidies by maternal plasma DNA sequencing", 《JOURNAL OF MATERNAL-FETAL AND NEONATAL MEDICINE》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111226281A (zh) * 2019-12-31 2020-06-02 深圳华大临床检验中心 确定染色体非整倍性、构建分类模型的方法和装置
CN111226281B (zh) * 2019-12-31 2023-03-21 深圳华大医学检验实验室 确定染色体非整倍性、构建分类模型的方法和装置

Also Published As

Publication number Publication date
WO2014153755A1 (fr) 2014-10-02

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Owner name: SHENZHEN BGI CORPORATION

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Effective date: 20150731

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Effective date of registration: 20150731

Address after: Yantian District of Shenzhen City, Guangdong province 518083 Hongan street No. 21 China Comprehensive Park 7 Building 7 layer -14 layer

Applicant after: BGI SHENZHEN CO LTD

Address before: Beishan Industrial Zone Building in Yantian District of Shenzhen city of Guangdong Province in 518083

Applicant before: BGI-Shenzhen

RJ01 Rejection of invention patent application after publication

Application publication date: 20141210

RJ01 Rejection of invention patent application after publication