CN104177682A - Novel medicinal plastic bottle material and preparation method thereof - Google Patents
Novel medicinal plastic bottle material and preparation method thereof Download PDFInfo
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- CN104177682A CN104177682A CN201410246457.0A CN201410246457A CN104177682A CN 104177682 A CN104177682 A CN 104177682A CN 201410246457 A CN201410246457 A CN 201410246457A CN 104177682 A CN104177682 A CN 104177682A
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K9/00—Use of pretreated ingredients
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/17—Component parts, details or accessories; Auxiliary operations
- B29C45/76—Measuring, controlling or regulating
- B29C45/77—Measuring, controlling or regulating of velocity or pressure of moulding material
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
- B29C45/17—Component parts, details or accessories; Auxiliary operations
- B29C45/76—Measuring, controlling or regulating
- B29C45/78—Measuring, controlling or regulating of temperature
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/20—Oxides; Hydroxides
- C08K3/22—Oxides; Hydroxides of metals
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/09—Carboxylic acids; Metal salts thereof; Anhydrides thereof
- C08K5/098—Metal salts of carboxylic acids
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K3/00—Use of inorganic substances as compounding ingredients
- C08K3/18—Oxygen-containing compounds, e.g. metal carbonyls
- C08K3/20—Oxides; Hydroxides
- C08K3/22—Oxides; Hydroxides of metals
- C08K2003/2237—Oxides; Hydroxides of metals of titanium
- C08K2003/2241—Titanium dioxide
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/10—Applications used for bottles
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2207/00—Properties characterising the ingredient of the composition
- C08L2207/06—Properties of polyethylene
- C08L2207/062—HDPE
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Mechanical Engineering (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention relates to a novel medicinal plastic bottle material and a preparation method thereof. The material comprises the following components of high density polyethylene, titanium dioxide, modified nanometer magnesium hydroxide and zinc stearate in the weight part ratio of 100: (0.5-1): (0.5-10): (0.3-1) at the environment temperature of 15-25 DEG C. The material disclosed by the invention has the beneficial effects that the material has excellent performances; the plastic surface energy is increased; bottle body decorating, printing, spraying or labelling and the like are benefited; the material can accord with service conditions of medicines and is used for holding the medicines, foods and the like. The preparation method is simple in process, can be used for producing high density polyethylene bottle bodies and has the advantages that on the premise that good adhesive property of the bottle bodies is guaranteed, the adding amount of the modified nanometer magnesium hydroxide and various auxiliaries is reduced, so that the raw material cost can be reduced, the residue index amount is reduced and the material accords with the medicinal grade; good effects are obtained in the aspects of appearance and product performances; and the raw materials are easy to buy and market promotion is benefitted.
Description
Technical field
The invention belongs to medical packing plastic bottle body proprietary material technical field, be specifically related to a kind of novel medicinal Plastic Bottle body proprietary material and preparation method thereof.
Background technology
At present, plastic drug package has that light weight, intensity are high, not cracky, with low cost, good seal performance, protection against the tide, health, meet the advantages such as the particular requirement of drug packaging, can both can be directly used in drug packaging without cleaning, drying, be a kind of good pharmaceutical pack container, be widely used on the market.Mainly made by the materials processing such as polyethylene or polypropylene.Along with the development of plastic drug package; the requirement of the aspect such as performance and material to plastic drug package is also more and more higher; to Plastic Bottle surface decoration, material protection, improvement be bonding etc., performance requriements is increasing in different application field; but various Plastic Bottle material structures are different from component, corresponding surface property also has notable difference.Due to the Plastic Bottle of the polyolefine material such as polypropylene and polyethylene machine-shaping, body surface can be very low, conventionally only has 30-34 dyne.Realize good bondingly, general requirement surface can be not less than 40 dyne, so limited the application functions such as some material body decorations, printing, spraying, labeling.A kind of a kind of new exclusive material that can improve Plastic Bottle body surface energy of market in urgent need.
In order to adapt to the different demands of Plastic Bottle surface-treated, out, conventional technology has: solvent cleaning (degreasing) in the technological development of existing multiple aftertreatment, corona treatment, short wave ultraviolet light radiotreatment, sand paper processing, sandblasting, plasma etching, chemical milling, heat treated etc., sign the packaging particular requirement in plastic drug package, implementing Plastic Bottle finished product aftertreatment meeting increases contamination probability, also can increase production cost.
The application of magnesium hydroxide in Plastic Bottle, mainly as fire retardant or fire-retardant filler at present, it discharges in conjunction with water during by decomposes, absorb a large amount of latent heat, reduce synthetic materials that it the fills surface temperature in flame, there is the polymer unwinds of inhibition and produced inflammable gas is carried out to cooling effect.Decomposing the magnesium oxide generating is again good refractory materials, also can help to improve the fire resistance of synthetic materials, and the water vapour that it is emitted simultaneously also can be used as a kind of smoke suppressant.Magnesium hydroxide be in generally acknowledged rubber and plastic industry, have fire-retardant, press down cigarette, fill the outstanding fire retardant of triple functions.Be widely used in the macromolecular materials such as rubber, chemical industry, building materials, plastics and electronics, unsaturated polyester and paint, coating.While use separately, consumption is generally 40%～60%.As (application number CN201010204995.5) PE/ magnesium hydroxide composite flame retardant material, it is characterized in that its raw material is made up of 40%～70% modified magnesium hydroxide and 30%～60% PE.So high loading level, must not cross 3.0% considerably beyond the inspection residue standard YBB00122002 " oral stable medicinal polythene bottle with high density " of plastic drug package containing opalizer.
The application of the low component magnesium hydroxide of 10% following content in Plastic Bottle still rarely has exploitation, and the present invention will carry out certain exploration in this respect.
Summary of the invention
For the above-mentioned deficiency of prior art, the object of this invention is to provide one and can improve Plastic Bottle body surface energy, meet again novel medicinal Plastic Bottle material of medical working conditions and preparation method thereof, ensureing under the prerequisite of the adhesiveproperties that body is good, reduce the addition of modified Nano magnesium hydroxide and various auxiliary agents, can reduce raw materials cost, also reduce residue index amount, meet medicinal rank.
For achieving the above object, the present invention is achieved by the following technical solutions:
A kind of novel medicinal Plastic Bottle material, composed of the following components: high density polyethylene(HDPE), titanium dioxide, modified Nano magnesium hydroxide and Zinic stearas, under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5～1:0.5～10:0.3～1.
As preferably, described novel medicinal Plastic Bottle material, under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: when Zinic stearas is 100:0.5:4:0.3, novel medicinal Plastic Bottle material of the present invention had both possessed good adhesiveproperties, reduced again the interpolation usage quantity of various auxiliary agents, reduced raw materials cost.
As preferably, described novel medicinal Plastic Bottle material, under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5:0.5:0.3.
As preferably, described novel medicinal Plastic Bottle material, under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5:2:0.3.
As preferably, described novel medicinal Plastic Bottle material, under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5:6:0.3.
As preferably, described novel medicinal Plastic Bottle material, under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5:10:0.3.
A preparation method for novel medicinal Plastic Bottle material, comprises the steps:
(1), high density polyethylene(HDPE), titanium dioxide, modified Nano magnesium hydroxide and Zinic stearas all mix in proportion; Under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5～1:0.5～10:0.3～1;
(2), mixture that step (1) is obtained puts into full-automatic injecting by feeder and blows blow moulding machine, after preheating, raw material is melten gel in the barrel screw rod of injection member, then in die cavity, becomes parison with high-pressure injection through hot runner; Adjust the temperature of mould with high temperature heat conductive oil simultaneously; Wherein barrel feeding section is 140-180 DEG C, and barrel stage casing is 180-195 DEG C, and barrel leading portion is 195-210 DEG C, and hot runner is 210-240 DEG C; The parison temperature distribution of turning oil control is: bottle diameter and bottle end 60-80 DEG C, bottle 80-130 DEG C, injection pressure is 58.8-98.06MPa, the compressed air blow molding under the pressure of 0.4-1.2MPa again of described parison, the finally demould plastics body that gets product.
Beneficial effect of the present invention is as follows:
Novel medicinal Plastic Bottle material of the present invention not only has good performance, has improved frosting energy, is conducive to body decoration, printing, spraying or labeling etc., can meet again medical working conditions, for holding medicine, food etc.
The preparation method of novel medicinal Plastic Bottle material of the present invention, technique is simple, can be for the production of high-density polyethylene bottle body, ensureing under the prerequisite of the adhesiveproperties that body is good, reduce the addition of modified Nano magnesium hydroxide and various auxiliary agents, can reduce raw materials cost, also reduce residue index amount, meet medicinal rank.In outward appearance and product performance, all obtain good effect; And starting material are easy to buying, are beneficial to marketing.
Brief description of the drawings
Fig. 1 is the impact (adhesive label impact on different ingredients material surface stripping strength) of adhesive label on plastic drug package material surface stripping strength.
Embodiment
Below in conjunction with specific embodiment, the present invention is further illustrated, but protection scope of the present invention is not limited to this.
Starting material in the present invention all can be prepared by mode well known in the art, also can adopt commercially available prod.
embodiment 1
The preparation method of novel medicinal Plastic Bottle material of the present invention, comprises the steps:
(1), under 20 ± 5 DEG C of envrionment temperatures, take high density polyethylene(HDPE) 25Kg, titanium dioxide 0.125Kg, modified Nano magnesium hydroxide 1Kg and Zinic stearas 0.075Kg, above-mentioned raw materials is mixed;
(2), mixture that step (1) is obtained puts into full-automatic injecting by feeder and blows blow moulding machine, after preheating, raw material is melten gel in the barrel screw rod of injection member, then in die cavity, becomes parison with high-pressure injection through hot runner; Adjust the temperature of mould with high temperature heat conductive oil simultaneously; Wherein barrel feeding section is 140 DEG C, and barrel stage casing is 180 DEG C, and barrel leading portion is 195 DEG C, and hot runner is 210 DEG C; The parison temperature distribution of turning oil control is: bottle diameter and bottle 60 DEG C, the end, and 80 DEG C of bottles, injection pressure is 58.8MPa, the compressed air blow molding under the programmed pressure of 0.4-1.2MPa again of described parison, the finally demould plastics body that gets product.
embodiment 2
The preparation method of novel medicinal Plastic Bottle material of the present invention, comprises the steps:
(1), under 20 ± 5 DEG C of envrionment temperatures, take high density polyethylene(HDPE) 25Kg, titanium dioxide 0.125Kg, modified Nano magnesium hydroxide 0.125Kg and Zinic stearas 0.075Kg, above-mentioned raw materials is mixed;
(2), mixture that step (1) is obtained puts into full-automatic injecting by feeder and blows blow moulding machine, after preheating, raw material is melten gel in the barrel screw rod of injection member, then in die cavity, becomes parison with high-pressure injection through hot runner; Adjust the temperature of mould with high temperature heat conductive oil simultaneously; Wherein barrel feeding section is 180 DEG C, and barrel stage casing is 195 DEG C, and barrel leading portion is 210 DEG C, and hot runner is 240 DEG C; The parison temperature distribution of turning oil control is: bottle diameter and bottle 80 DEG C, the end, and 130 DEG C of bottles, injection pressure is 98.06MPa, the compressed air blow molding under the programmed pressure of 0.4-1.2MPa again of described parison, the finally demould plastics body that gets product.
embodiment 3
The preparation method of novel medicinal Plastic Bottle material of the present invention, comprises the steps:
(1), under 20 ± 5 DEG C of envrionment temperatures, take high density polyethylene(HDPE) 25Kg, titanium dioxide 0.125Kg, modified Nano magnesium hydroxide 0.5Kg and Zinic stearas 0.075Kg, above-mentioned raw materials is mixed;
(2), mixture that step (1) is obtained puts into full-automatic injecting by feeder and blows blow moulding machine, after preheating, raw material is melten gel in the barrel screw rod of injection member, then in die cavity, becomes parison with high-pressure injection through hot runner; Adjust the temperature of mould with high temperature heat conductive oil simultaneously; Wherein barrel feeding section is 160 DEG C, and barrel stage casing is 187.5 DEG C, and barrel leading portion is 202.5 DEG C, and hot runner is 225 DEG C; The parison temperature distribution of turning oil control is: bottle diameter and bottle 70 DEG C, the end, and 105 DEG C of bottles, injection pressure is 78.43MPa, the compressed air blow molding under the programmed pressure of 0.4-1.2MPa again of described parison, the finally demould plastics body that gets product.
embodiment 4
The preparation method of novel medicinal Plastic Bottle material of the present invention, comprises the steps:
(1), under 20 ± 5 DEG C of envrionment temperatures, take high density polyethylene(HDPE) 25Kg, titanium dioxide 0.125Kg, modified Nano magnesium hydroxide 1.5Kg and Zinic stearas 0.075Kg, above-mentioned raw materials is mixed;
(2), mixture that step (1) is obtained puts into full-automatic injecting by feeder and blows blow moulding machine, after preheating, raw material is melten gel in the barrel screw rod of injection member, then in die cavity, becomes parison with high-pressure injection through hot runner; Adjust the temperature of mould with high temperature heat conductive oil simultaneously; Wherein barrel feeding section is 150 DEG C, and barrel stage casing is 185 DEG C, and barrel leading portion is 200 DEG C, and hot runner is 220 DEG C; The parison temperature distribution of turning oil control is: bottle diameter and bottle 65 DEG C, the end, and 90 DEG C of bottles, injection pressure is 65MPa, the compressed air blow molding under the programmed pressure of 0.4-1.2MPa again of described parison, the finally demould plastics body that gets product.
embodiment 5
The preparation method of novel medicinal Plastic Bottle material of the present invention, comprises the steps:
(1), under 20 ± 5 DEG C of envrionment temperatures, take high density polyethylene(HDPE) 25Kg, titanium dioxide 0.125Kg, modified Nano magnesium hydroxide 2.5Kg and Zinic stearas 0.075Kg, above-mentioned raw materials is mixed;
(2), mixture that step (1) is obtained puts into full-automatic injecting by feeder and blows blow moulding machine, after preheating, raw material is melten gel in the barrel screw rod of injection member, then in die cavity, becomes parison with high-pressure injection through hot runner; Adjust the temperature of mould with high temperature heat conductive oil simultaneously; Wherein barrel feeding section is 170 DEG C, and barrel stage casing is 190 DEG C, and barrel leading portion is 205 DEG C, and hot runner is 230 DEG C; The parison temperature distribution of turning oil control is: bottle diameter and bottle 75 DEG C, the end, and 100 DEG C of bottles, injection pressure is 85MPa, the compressed air blow molding under the programmed pressure of 0.4-1.2MPa again of described parison, the finally demould plastics body that gets product.
embodiment 6
The preparation method of novel medicinal Plastic Bottle material of the present invention, comprises the steps:
(1), under 20 ± 5 DEG C of envrionment temperatures, take high density polyethylene(HDPE) 25Kg, titanium dioxide 0.25Kg, modified Nano magnesium hydroxide 1.25Kg and Zinic stearas 0.25Kg, above-mentioned raw materials is mixed;
(2), mixture that step (1) is obtained puts into full-automatic injecting by feeder and blows blow moulding machine, after preheating, raw material is melten gel in the barrel screw rod of injection member, then in die cavity, becomes parison with high-pressure injection through hot runner; Adjust the temperature of mould with high temperature heat conductive oil simultaneously; Wherein barrel feeding section is 175 DEG C, and barrel stage casing is 192 DEG C, and barrel leading portion is 208 DEG C, and hot runner is 230 DEG C; The parison temperature distribution of turning oil control is: bottle diameter and bottle 72 DEG C, the end, and 129 DEG C of bottles, injection pressure is 90MPa, the compressed air blow molding under the programmed pressure of 0.4-1.2MPa again of described parison, the finally demould plastics body that gets product.
embodiment 7
The preparation method of novel medicinal Plastic Bottle material of the present invention, comprises the steps:
(1), under 20 ± 5 DEG C of envrionment temperatures, take high density polyethylene(HDPE) 25Kg, titanium dioxide 0.1875Kg, modified Nano magnesium hydroxide 0.25Kg and Zinic stearas 0.1625Kg, above-mentioned raw materials is mixed;
(2), mixture that step (1) is obtained puts into full-automatic injecting by feeder and blows blow moulding machine, after preheating, raw material is melten gel in the barrel screw rod of injection member, then in die cavity, becomes parison with high-pressure injection through hot runner; Adjust the temperature of mould with high temperature heat conductive oil simultaneously; Wherein barrel feeding section is 142 DEG C, and barrel stage casing is 183 DEG C, and barrel leading portion is 196 DEG C, and hot runner is 223 DEG C; The parison temperature distribution of turning oil control is: bottle diameter and bottle 62 DEG C, the end, and 85 DEG C of bottles, injection pressure is 73MPa, the compressed air blow molding under the programmed pressure of 0.4-1.2MPa again of described parison, the finally demould plastics body that gets product.
comparative example 1
As production technique of the present invention, in change comparative example 1, do not add modified Nano magnesium hydroxide, make plastic drug package material.
performance test
Test ambient temperature is 23 DEG C, humidity is 65%, test critical surfaces energy according to testing standard DIN ISO 8296, according to testing standard ASTM D3359-97 test adhesion test, according to testing standard Chinese Pharmacopoeia≤3.0% test residue on ignition, test heavy metal according to testing standard Chinese Pharmacopoeia≤1mg/kg, according to testing standard YBB00122002 test drug release test, according to two annex XI C test undue toxicities of testing standard Chinese Pharmacopoeia version in 2000, test result sees the following form 1:
| ? | Critical surfaces energy (m N/m) | Adhesion test (level) | Residue on ignition (%) | Heavy metal (mg/kg) | Drug release test | Undue toxicity |
| Embodiment 1 | 46 | 4B | 2.48 | <1mg/kg | Do not exceed standard | Conform with the regulations |
| Embodiment 2 | 33 | 1B | 1.05 | <1mg/kg | Do not exceed standard | Conform with the regulations |
| Embodiment 3 | 36 | 2B | 1.80 | <1mg/kg | Do not exceed standard | Conform with the regulations |
| Embodiment 4 | 58 | 4B | 3.87 | <1mg/kg | Do not exceed standard | Conform with the regulations |
| Embodiment 5 | 87 | 5B | 6.20 | <1mg/kg | Do not exceed standard | Conform with the regulations |
| Embodiment 6 | 60 | 5B | 4.13 | <1mg/kg | Do not exceed standard | Conform with the regulations |
| Embodiment 7 | 40 | 3B | 1.36 | <1mg/kg | Do not exceed standard | Conform with the regulations |
| Comparative example 1 | 31 | 1B | 0.45 | <1mg/kg | Do not exceed standard | Conform with the regulations |
From actual effect, the stripping strength of adhesive label in plastic drug package material is to weigh the common counter of adhesiveproperties, test ambient temperature in Fig. 1 is 23 DEG C, humidity 65%, and sticky label paper is placed 2 hours on the surface of embodiment 1-7 and comparative example under this condition.This touchstone example test material therefor is metal alignment plate.
As shown in Figure 1, the stripping strength of the plastic drug package material that embodiment 1-7 the makes example that is near the mark, improves a lot with respect to comparative example stripping strength, realistic effect.
Novel medicinal Plastic Bottle material of the present invention not only has good performance, has improved frosting energy, is conducive to body decoration, printing, spraying or labeling etc., can meet again medical working conditions, for holding medicine, food etc.
The preparation method of novel medicinal Plastic Bottle material of the present invention, technique is simple, can be for the production of high-density polyethylene bottle body, ensureing under the prerequisite of the adhesiveproperties that body is good, reduce the addition of modified Nano magnesium hydroxide and various auxiliary agents, can reduce raw materials cost, also reduce residue index amount, meet medicinal rank.In outward appearance and product performance, all obtain good effect; And starting material are easy to buying, are beneficial to marketing.
Above-described embodiment is only for the inventive concept of the present invention of explaining, but not restriction to rights protection of the present invention, allly utilizes this design to carry out the change of unsubstantiality to the present invention, all should fall into protection scope of the present invention.
Claims (7)
1. a novel medicinal Plastic Bottle material, it is characterized in that composed of the following components: high density polyethylene(HDPE), titanium dioxide, modified Nano magnesium hydroxide and Zinic stearas, under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5～1:0.5～10:0.3～1.
2. novel medicinal Plastic Bottle material as claimed in claim 1, it is characterized in that: under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5:4:0.3.
3. novel medicinal Plastic Bottle material as claimed in claim 1, it is characterized in that: under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5:0.5:0.3.
4. novel medicinal Plastic Bottle material as claimed in claim 1, it is characterized in that: under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5:2:0.3.
5. novel medicinal Plastic Bottle material as claimed in claim 1, it is characterized in that: under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5:6:0.3.
6. novel medicinal Plastic Bottle material as claimed in claim 1, it is characterized in that: under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5:10:0.3.
7. a preparation method for novel medicinal Plastic Bottle material, is characterized in that comprising the steps: that (1), high density polyethylene(HDPE), titanium dioxide, modified Nano magnesium hydroxide and Zinic stearas all mix in proportion; Under 20 ± 5 DEG C of envrionment temperatures, the proportioning of described each component is in parts by weight, high density polyethylene(HDPE): titanium dioxide: modified Nano magnesium hydroxide: Zinic stearas is 100:0.5～1:0.5～10:0.3～1; (2), mixture that step (1) is obtained puts into full-automatic injecting by feeder and blows blow moulding machine, after preheating, raw material is melten gel in the barrel screw rod of injection member, then in die cavity, becomes parison with high-pressure injection through hot runner; Adjust the temperature of mould with high temperature heat conductive oil simultaneously; Wherein barrel feeding section is 140-180 DEG C, and barrel stage casing is 180-195 DEG C, and barrel leading portion is 195-210 DEG C, and hot runner is 210-240 DEG C; The parison temperature distribution of turning oil control is: bottle diameter and bottle end 60-80 DEG C, bottle 80-130 DEG C, injection pressure is 58.8-98.06MPa, the compressed air blow molding under the pressure of 0.4-1.2MPa again of described parison, the finally demould plastics body that gets product.
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| CN201410246457.0A CN104177682A (en) | 2014-06-05 | 2014-06-05 | Novel medicinal plastic bottle material and preparation method thereof |
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| CN201410246457.0A CN104177682A (en) | 2014-06-05 | 2014-06-05 | Novel medicinal plastic bottle material and preparation method thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106009145A (en) * | 2016-05-17 | 2016-10-12 | 安徽丰华医药包装有限公司 | Production technology of HDPE (high-density polyethylene) bottles for oral solid drugs |
| CN106046508A (en) * | 2016-08-08 | 2016-10-26 | 陆志强 | Preparation method of polyethylene composite material used for packaging bottles |
| CN107880356A (en) * | 2017-11-28 | 2018-04-06 | 安徽益顺塑业有限公司 | A kind of preparation method for being not easy chromoplastic material bottle |
| CN109880309A (en) * | 2019-01-21 | 2019-06-14 | 黄茂仁 | A kind of hard plastic material cillin bottle and preparation method thereof |
| CN111688376A (en) * | 2020-06-22 | 2020-09-22 | 杭州迅美塑料制品有限责任公司 | Printing process for gradient-color cosmetic bottle |
| CN112266513A (en) * | 2020-10-27 | 2021-01-26 | 中山汇丰医用包装科技有限公司 | Plastic bottle for containing medicine and preparation method and application thereof |
| CN113736176A (en) * | 2021-09-14 | 2021-12-03 | 新汉方(广东)科技有限公司 | Composite food-grade oral liquid bottle and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106009145A (en) * | 2016-05-17 | 2016-10-12 | 安徽丰华医药包装有限公司 | Production technology of HDPE (high-density polyethylene) bottles for oral solid drugs |
| CN106046508A (en) * | 2016-08-08 | 2016-10-26 | 陆志强 | Preparation method of polyethylene composite material used for packaging bottles |
| CN107880356A (en) * | 2017-11-28 | 2018-04-06 | 安徽益顺塑业有限公司 | A kind of preparation method for being not easy chromoplastic material bottle |
| CN109880309A (en) * | 2019-01-21 | 2019-06-14 | 黄茂仁 | A kind of hard plastic material cillin bottle and preparation method thereof |
| CN111688376A (en) * | 2020-06-22 | 2020-09-22 | 杭州迅美塑料制品有限责任公司 | Printing process for gradient-color cosmetic bottle |
| CN111688376B (en) * | 2020-06-22 | 2022-02-11 | 杭州迅美塑料制品有限责任公司 | Printing process for gradient-color cosmetic bottle |
| CN112266513A (en) * | 2020-10-27 | 2021-01-26 | 中山汇丰医用包装科技有限公司 | Plastic bottle for containing medicine and preparation method and application thereof |
| CN113736176A (en) * | 2021-09-14 | 2021-12-03 | 新汉方(广东)科技有限公司 | Composite food-grade oral liquid bottle and preparation method thereof |
| CN113736176B (en) * | 2021-09-14 | 2023-09-22 | 新汉方(广东)科技有限公司 | Composite food-grade oral liquid bottle and preparation method thereof |
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Application publication date: 20141203 |