CN104147197A - Medicine for treating tinea pedis and preparation method thereof - Google Patents

Medicine for treating tinea pedis and preparation method thereof Download PDF

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Publication number
CN104147197A
CN104147197A CN201410376979.2A CN201410376979A CN104147197A CN 104147197 A CN104147197 A CN 104147197A CN 201410376979 A CN201410376979 A CN 201410376979A CN 104147197 A CN104147197 A CN 104147197A
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China
Prior art keywords
medicine
tinea pedis
parts
treatment
radix sophorae
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Pending
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CN201410376979.2A
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Chinese (zh)
Inventor
方方
杨逸霏
宋振华
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Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
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Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
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Priority to CN201410376979.2A priority Critical patent/CN104147197A/en
Publication of CN104147197A publication Critical patent/CN104147197A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a medicine for treating tinea pedis and a preparation method thereof. The medicine comprises the following raw material medicines: 5-20 parts of folium cortex eucommiae leaf, 10-25 parts of radix sophorae flavescentis, 5-15 parts of golden cypress and 3-15 parts of portulaca oleracea. 10-20 times of vinegar is added into the raw material medicines, and the raw material medicines are soaked for 7-10 days in a sealed container. When being used for treating tinea pedis, the medicine is high in effect taking speed and good in curative effect, and the disease does not relapse after being healed.

Description

A kind of medicine for the treatment of tinea pedis and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of tinea pedis and preparation method thereof, belong to field of pharmaceutical technology.
Background technology
Tinea pedis (popular name " tinea pedis ", beriberi), is that fungal infection causes, its skin lesion is first one-sided (being single foot) generation often, after several weeks or several months, just infects to offside.Vesicle mainly appears at toe abdomen and toe side, is most commonly between three or four toes, and vola also can occur, in property phlysis, can be fused into gradually bulla for deeply.The skin lesion of tinea pedis has a feature, i.e. clear border can be gradually to external expansion.Because of PD or scratch, can there is erosion, sepage, even antibacterial infects, there is pustule etc.
The medicine of the treatment tinea pedis of doctor trained in Western medicine classics has topical application salicylic acid at present, the cutin cracking-off agents such as benzoic acid, oral external azole and Allylamines antifungal drug, but along with clinical extensive application, the phenomenon that produces drug resistance also increases gradually, easily recurrence after drug withdrawal, the restriction of untoward reaction and medicine cost are higher in addition, and tinea manus and pedis treatment still faces many challenges, and Chinese medicine is having unique advantage aspect treatment tinea manus and pedis, show good results, untoward reaction is few, cheap etc.
Summary of the invention
The object of the invention is the deficiency of the medicine in order to overcome western medical treatment tinea pedis, propose a kind of Chinese medicine for the treatment of tinea pedis and preparation method thereof.The present invention is evident in efficacy, has no side effect.
Object of the present invention realizes by following scheme:
A medicine for the treatment of tinea pedis, is made up of following bulk drugs:
Folium Eucommiae 5-20 part, Radix Sophorae Flavescentis 10-25 part, Cortex Phellodendri 5-15 part, Herba Portulacae 3-15 part.
The best is:
15 parts of Folium Eucommiaes, 20 parts of Radix Sophorae Flavescentiss, 10 parts of Cortex Phellodendris, 10 parts of Herba Portulacaes.
In above each component, weight is calculated with crude drug, if weight is in grams, and this composition consumption once.
Each composition is by weight as proportioning above, in the time producing, can increase or reduce according to corresponding ratio, as large-scale production can with kilogram or taking ton as unit, weight can increase or reduce, but the crude drug weight proportion constant rate between each component, consumption is once constant.
Medicine of the present invention is prepared by the following method: take by weight ratio Folium Eucommiae, Radix Sophorae Flavescentis, Cortex Phellodendri, Herba Portulacae, add 10-20 vinegar doubly, with hermetic container immersion 7-10 days.
The invention is characterized in: be usually used in treating in the traditional Chinese medical science on the basis of medicine Radix Sophorae Flavescentis, Cortex Phellodendri, Herba Portulacae of tinea pedis, increased Folium Eucommiae, obviously increased therapeutic effect.Drug therapy tinea pedis instant effect of the present invention, good effect, short treating period, non-relapse after healing, economical convenient, overcome the easy drug resistance of Western medicine, erious adverse reaction, price, the easily drawback of recurrence.
For a better understanding of the present invention, below, further illustrate the beneficial effect of the present invention's treatment by test example.Test is below intended to further illustrate effect of the present invention, but not restriction of the present invention.
1, the routine patient of physical data 75 all has typical clinical symptoms, and fungus microscope examination is all positive, within two weeks, has not used other parts and whole body antifungal drug before medication, and patient is divided into two groups at random, matched group 36 examples, treatment group 39 examples.
2, method matched group takes Radix Sophorae Flavescentis 200g, Cortex Phellodendri 100g, Herba Portulacae 100g, adds the vinegar of 8000ml, soaks foot bath after 7 days with hermetic container, 1 time/d, each about 1h, 10 weeks is 1 course for the treatment of, be used in conjunction 2 courses for the treatment of, treatment finishes to judge curative effect after 1 month, and does fungus microscope examination.
Treatment group takes Folium Eucommiae 150g, Radix Sophorae Flavescentis 200g, Cortex Phellodendri 100g, Herba Portulacae 100g, adds the vinegar of 8000ml, soaks foot bath after 7 days with hermetic container, 1 time/d, each about 1h, 10 weeks is 1 course for the treatment of, be used in conjunction 2 courses for the treatment of, treatment finishes to judge curative effect after 1 month, and does fungus microscope examination.
3, the standard of curative effect evaluation recovery from illness: symptom disappears completely; Effective: resolution of symptoms is greater than 70%; Effective: resolution of symptoms is greater than 30%; Invalid: resolution of symptoms is less than 30% or increase the weight of.Effective percentage is recovery from illness, effective and effective sum.Mycology curative effect: remove as microscopy feminine gender, do not remove as the microscopy positive.
4, all patients of result better tolerance in treatment, has no adverse reaction.
Matched group 36 examples, recovery from illness 19 examples, effective 10 examples, effective 3 examples, invalid 4 examples, effective percentage is 88.9%; Negative 27 examples of fungus, clearance rate is 75.0%.
Treatment group 39 examples, recovery from illness 29 examples, effective 8 examples, effective 2 examples, invalid 0 example, effective percentage is 100%; Negative 39 examples of fungus, clearance rate is 100%.
Follow up a case by regular visits to 1 year, matched group recurs 8 examples, and relapse rate is 22.2%; Treatment group recurs 0 example, and relapse rate is 0.0%.
Detailed description of the invention
Embodiment 1:
Take Folium Eucommiae 50g, Radix Sophorae Flavescentis 100g, Cortex Phellodendri 50g, Herba Portulacae 30g.Add the vinegar of 2300ml, with hermetic container immersion 7 days, must treat the medication of steeping foot of tinea pedis.
Embodiment 2:
Take Folium Eucommiae 200g, Radix Sophorae Flavescentis 250g, Cortex Phellodendri 150g, Herba Portulacae 150g.Add the vinegar of 5400ml, with hermetic container immersion 10 days, must treat the medication of steeping foot of tinea pedis.
Embodiment 3:
Take Folium Eucommiae 150g, Radix Sophorae Flavescentis 250g, Cortex Phellodendri 50g, Herba Portulacae 90g.Add the vinegar of 8000ml, with hermetic container immersion 7 days, to obtain final product.
Embodiment 4:
Take Folium Eucommiae 90g, Radix Sophorae Flavescentis 90g, Cortex Phellodendri 150g, Herba Portulacae 90g.Add the vinegar of 5500ml, with hermetic container immersion 9 days, must treat the medication of steeping foot of tinea pedis.
Embodiment 4:
Take Folium Eucommiae 200g, Radix Sophorae Flavescentis 100g, Cortex Phellodendri 120g, Herba Portulacae 120g.Add the vinegar of 7000ml, with hermetic container immersion 10 days, must treat the medication of steeping foot of tinea pedis.

Claims (3)

1. treat a medicine for tinea pedis, it is characterized in that being formed by following bulk drugs: Folium Eucommiae 5-20 part, Radix Sophorae Flavescentis 10-25 part, Cortex Phellodendri 5-15 part, Herba Portulacae 3-15 part.
2. according to a kind of medicine for the treatment of tinea pedis of claim 1, it is characterized in that being formed by following bulk drugs: 15 parts of Folium Eucommiaes, 20 parts of Radix Sophorae Flavescentiss, 10 parts of Cortex Phellodendris, 10 parts of Herba Portulacaes.
3. according to a kind of medicine for the treatment of tinea pedis of claim 1, it is characterized in that preparing by the following method: take by weight ratio Folium Eucommiae, Radix Sophorae Flavescentis, Cortex Phellodendri, Herba Portulacae, add 10-20 vinegar doubly, with hermetic container immersion 7-10 days.
CN201410376979.2A 2014-08-04 2014-08-04 Medicine for treating tinea pedis and preparation method thereof Pending CN104147197A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106309664A (en) * 2015-07-06 2017-01-11 罗旭 External use traditional Chinese medicine for treating tinea pedis and usage method thereof
CN114767755A (en) * 2022-03-23 2022-07-22 吉林省本草中药有限公司 Traditional Chinese medicine composition for treating beriberi and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102397378A (en) * 2010-09-19 2012-04-04 张玉芳 Medicine for treating beriberi
CN103690656A (en) * 2013-12-13 2014-04-02 姜兴文 Traditional Chinese herbal medicine for treating tinea and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102397378A (en) * 2010-09-19 2012-04-04 张玉芳 Medicine for treating beriberi
CN103690656A (en) * 2013-12-13 2014-04-02 姜兴文 Traditional Chinese herbal medicine for treating tinea and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
李茂青: "中西医结合治疗浅部真菌感染", 《中国社区医师》 *
谢观主编: "《中华医药大辞典》", 31 August 1994, 辽宁科学技术出版社 *
赵卫等: "黄马煎剂治疗渗出性皮肤病186例", 《陕西中医》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106309664A (en) * 2015-07-06 2017-01-11 罗旭 External use traditional Chinese medicine for treating tinea pedis and usage method thereof
CN114767755A (en) * 2022-03-23 2022-07-22 吉林省本草中药有限公司 Traditional Chinese medicine composition for treating beriberi and preparation method thereof

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Application publication date: 20141119