CN104138259B - The chest breath signal acquisition method not affected by sleeping posture and system - Google Patents

The chest breath signal acquisition method not affected by sleeping posture and system Download PDF

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CN104138259B
CN104138259B CN201410311693.6A CN201410311693A CN104138259B CN 104138259 B CN104138259 B CN 104138259B CN 201410311693 A CN201410311693 A CN 201410311693A CN 104138259 B CN104138259 B CN 104138259B
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signal
chest
experimenter
electrical impedance
electrode
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CN104138259A (en
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蒋庆
周广敏
刘官正
王瑛
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National Sun Yat Sen University
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  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

A kind of chest breath signal acquisition method not affected by sleeping posture and system, method is: gather respectively experimenter lying on the back, lie on the left side and breathing flow velocity signal that under right lateral position, the electrical impedance signal of its chest and BIOPAC TSD117 record;The electrical impedance signal collected is carried out analog digital conversion, obtains respectively and lie on the back, lie on the left side and the electrical impedance digital signal of experimenter's chest time crouch in right side;According to the electrical impedance digital signal obtained and breathing flow velocity signal, extract fixed reference feature value respectively;Calibrate according to the chest breath signal that described experimenter is collected under different sleeping postures by fixed reference feature value.System includes: electrical impedance signal pickup assembly and BIOPAC TSD117.Simply, easily operate, and the simple in construction of system, anti-jamming effectiveness is good, can gather experimenter's chest breath signal under the influence of not by sleeping posture rapidly and accurately, and then realizes the early stage to some pulmonary disease and detect for the method for the present invention.

Description

The chest breath signal acquisition method not affected by sleeping posture and system
Technical field
The present invention relates to medical monitoring technical field, especially relate to a kind of chest breathing not affected by sleeping posture and believe Number acquisition method and system.
Background technology
At present, the most commonly used dynamic spirometry that such as forces, forced oscillation, interrupter technology obtains breathing The mechanics parameter in road.Equipment required for these methods is the heaviest not easily shifted but also needs the conjunction of patient's actively patience Make.Standard polysomnogram instrument but can only use in sleep laboratory, this greatly limits its popularization and application.Breath stream Gauge is used to measure the goldstandard breathing flow velocity signal, but owing to needing when it is measured to use nose clip or breathing mask prevents Gas leakage, this is prone to cause insomnia or uncomfortable to patient.Breathe additionally, respiration measurement temperature-sensitive element is also welcome a measurement The instrument of signal, but it remains insecure in quantitative measurement.Thorax impedance capacity trace art, is that one breathes prison easily Survey technology, was used since the middle of last century always.But, nearest research finds, it is on monitoring sleep obstacle There are some shortcomings.Brouillette etc. report when use thorax impedance capacity trace art time some typically disturb, such as by the heart The variability etc. of dirty induction.Additionally, Larsen etc. point out, the small movements of health also can greatly interfere with monitoring of respiration.Therefore, One of problem of monitoring breath state is the most accurately to measure breath signal without causing discomfort to patient.
Summary of the invention
Present invention aims to above-mentioned existing problems and deficiency, it is provided that a kind of technology is simple, measures accurately The chest breath signal acquisition method not affected by sleeping posture and system.
The technical scheme is that and be achieved in that:
The chest breath signal acquisition method not affected by sleeping posture of the present invention, is characterized in including walking as follows Rapid:
S1, respectively gather experimenter lying on the back, lie on the left side and under right lateral position its chest electrical impedance signal and The breathing flow velocity signal that BIOPAC TSD117 records;
S2, lie on the back to collect, lie on the left side and under right lateral position, the electrical impedance signal of experimenter's chest carries out modulus Conversion, obtains respectively and lies on the back, lies on the left side and the electrical impedance digital signal of experimenter's chest time crouch in right side;
S3, lie on the back according to obtain, lie on the left side and the electrical impedance digital signal of experimenter's chest and breath stream time crouch in right side Speed signal, extracts fixed reference feature value respectively;
S4, according to the fixed reference feature value obtained, the electricity to the chest that described experimenter collects under different sleeping postures Impedance signal is calibrated.
Wherein, the concrete operation method of above-mentioned steps S1 is as follows:
S11, left and right nipple line and left side midaxillary line point of intersection the constant excitation electrode respectively of two ends up and down and Measure the positive pole of electrode, distinguish constant excitation at the line of left and right nipple with the two ends up and down of the point of intersection of right side midaxillary line simultaneously Electrode and the negative pole of measurement electrode;
S12, under experimenter is in back floating position time, clamp nose with nose clip, then recorded by BIOPAC TSD117 Experimenter's breathing flow velocity signal under different sleeping postures, simultaneously by exciting electrode to experimenter's input stimulus electric current;
S13, according to exciting current and measure voltage, according to Ohm's law calculate experimenter under different sleeping postures its The electrical impedance signal of chest.
The concrete operation method of above-mentioned steps S3 is as follows:
S31, according to obtain the electrical impedance digital signal IP of experimenter's chest when lying on the backDDAnd breathe flow velocity signal PNTDD, The electrical impedance digital signal IP of experimenter's chest when lying on the left sideLDAnd breathe flow velocity signal PNTLD, experimenter's chest time crouching in right side Electrical impedance digital signal IPRDAnd breathe flow velocity signal PNTRD, it is zero by average after filter filtering, then basisIt is calculated the breathing plethysmogram signal VPNT under different sleeping posture respectivelyDD, VPNTLD, VPNTRD;Its In, variable T is time interval;
The electrical impedance digital signal IP of experimenter's chest when S32, basis are lain on the backDDAnd breathe plethysmogram signal VPNTDD, left side The electrical impedance digital signal IP of experimenter's chest time sleepingLDAnd breathe plethysmogram signal VPNTLD, the electricity of experimenter's chest time crouching in right side Impedance digital signal IPRDAnd breathe plethysmogram signal VPNTRD, do linear regression analysis respectively and be designated as: y1=k1x1+b1, y2=k2x2+ b2, y3=k3x3+b3, then k1As the first fixed reference feature value, k2As the second fixed reference feature value, k3As the 3rd fixed reference feature Value;Wherein, y is for breathing plethysmogram signal, and x is electrical impedance digital signal, the parameter produced when b is to do linear regression.
Above-mentioned steps S4 is according to above-mentioned fixed reference feature value k1, k2, k3Average, be k=(k1+ k2+ k3)/3, Then using k as correction coefficient.
The chest breath signal acquisition system not affected by sleeping posture of the present invention, is characterized in including for adopting Collect the electrical impedance signal pickup assembly of the electrical impedance signal of experimenter's chest and for detecting the breathing flow velocity signal of experimenter BIOPAC TSD117, wherein said electrical impedance signal pickup assembly includes power module, constant-current source module, multi-channel switch mould Block, data acquisition module, signal processing module, exciting electrode and measurement electrode, described constant-current source module is for for measuring electrode Current excitation is provided, described multi-channel switch module respectively with exciting electrode, measure electrode, constant-current source module and data acquisition module Block connects and for controlling to be fixed on the exciting current of the exciting electrode of experimenter's chest diverse location and receiving measurement electrode The voltage signal received also is transferred to data acquisition module by voltage signal, and described data acquisition module is according to the electricity received Pressure signal calculates the electrical impedance signal of experimenter's chest, described signal processing module be connected with data acquisition module and be used for right The electrical impedance signal that data acquisition module transmits carries out analog digital conversion and is analyzed signal processing, described power module Electrically connect with constant-current source module, multi-channel switch module, data acquisition module and signal processing module respectively and be used for each Module is powered.
The present invention compared with prior art, has the advantages that
Due to the fact that be make use of bio-electrical impedance technology to measure chest breath signal, the most simple, anti-dry Disturb effective, measurement data can be gathered the most exactly, be effectively reduced the usage quantity of measuring instrument, and simple to operate, Experimenter's chest breath signal under the influence of not by sleeping posture can be gathered rapidly and accurately, and then realize some pulmonary The early stage detection of disease.
The present invention is further illustrated below in conjunction with the accompanying drawings.
Accompanying drawing explanation
Fig. 1 is the structural representation of electrical impedance signal pickup assembly in the present invention.
Fig. 2 be exciting electrode in the present invention with measure electrode wear schematic diagram.
Detailed description of the invention
The chest breath signal acquisition method not affected by sleeping posture of the present invention, comprises the following steps:
S1, respectively gather experimenter lying on the back, lie on the left side and under right lateral position its chest electrical impedance signal and The breathing flow velocity signal that BIOPAC TSD117 records;
S2, lie on the back to collect, lie on the left side and under right lateral position, the electrical impedance signal of experimenter's chest carries out modulus Conversion, obtains respectively and lies on the back, lies on the left side and the electrical impedance digital signal of experimenter's chest time crouch in right side;
S3, lie on the back according to obtain, lie on the left side and the electrical impedance digital signal of experimenter's chest and breath stream time crouch in right side Speed signal, extracts fixed reference feature value respectively;
S4, according to the fixed reference feature value obtained, the electricity to the chest that described experimenter collects under different sleeping postures Impedance signal (that is: chest breath signal) is calibrated.
When being embodied as, it is to use the chest breath signal acquisition system not affected by sleeping posture to carry out to experimenter not Calibrating of the chest breath signal affected by sleeping posture, its main working process includes: by classical four electrode method to not The breathing flow velocity signal recorded with BIOPAC TSD117 it is acquired with the electrical impedance signal of sleeping posture pectus, and by institute State the analyzing and processing carrying out signal after electrical impedance signal is converted to digital signal, according to the chest under the different sleeping postures obtained Electrical impedance digital signal and breathe plethysmogram signal, extract fixed reference feature value, according to fixed reference feature value, to described experimenter not Calibrate with the chest breath signal collected under sleeping posture.
In the present embodiment, the concrete operation method of above-mentioned steps S1 is as follows:
S11, left and right nipple line and left side midaxillary line point of intersection the constant excitation electrode respectively of two ends up and down and Measure the positive pole of electrode, distinguish constant excitation at the line of left and right nipple with the two ends up and down of the point of intersection of right side midaxillary line simultaneously Electrode and the negative pole of measurement electrode.Specifically, as in figure 2 it is shown, can be by the negative pole I of exciting electrode-It is fixed on the company of left and right nipple The upper end of the point of intersection of line and right side midaxillary line, by exciting electrode I+Positive pole be fixed on the line of left and right nipple and left side midaxilla The upper end of the point of intersection of line;The negative pole V of electrode will be measured-It is fixed on the line of left and right nipple and the point of intersection of right side midaxillary line Lower end, specifically, is being close to right side exciting electrode I-Lower section to described measurement electrode V-It is fixed;Electrode V will be measured+ Positive pole be fixed on the lower end of the line of left and right nipple and the point of intersection of left side midaxillary line;Specifically, it is being close to left side excitation Electrode I+Lower section to described measurement electrode V+It is fixed;
S12, under experimenter is in back floating position time, clamp nose with nose clip, then recorded by BIOPAC TSD117 Experimenter's breathing flow velocity signal under different sleeping postures, simultaneously by exciting electrode to experimenter's input stimulus electric current;
S13, according to exciting current and measure voltage, according to Ohm's law calculate experimenter under different sleeping postures its The electrical impedance signal of chest.Specifically, it is by described measurement electrode, collects the voltage difference of the chest of described experimenter Value, the voltage difference of experimenter's chest is (V+ - V-), and be I to the exciting current of experimenter's input, according to described excitation electricity Stream and the voltage difference of described left side chest, calculate the electrical impedance signal of left side chest respectively according to Ohm's law.Specifically, The electrical impedance signal of experimenter's chest is R=| (V+ - V-) |/I, | (V+ - V-) | for the absolute value of the voltage difference of chest, with Ensure that calculated electrical impedance signal is positive number.And in the present embodiment, the concrete operation method of above-mentioned steps S3 is as follows:
S31, according to obtain the electrical impedance digital signal IP of experimenter's chest when lying on the backDDAnd breathe flow velocity signal PNTDD, The electrical impedance digital signal IP of experimenter's chest when lying on the left sideLDAnd breathe flow velocity signal PNTLD, experimenter's chest time crouching in right side Electrical impedance digital signal IPRDAnd breathe flow velocity signal PNTRD, it is zero by average after filter filtering, then basisIt is calculated the breathing plethysmogram signal VPNT under different sleeping posture respectivelyDD, VPNTLD, VPNTRD;Its In, variable T is time interval;
The electrical impedance digital signal IP of experimenter's chest when S32, basis are lain on the backDDAnd breathe plethysmogram signal VPNTDD, left side The electrical impedance digital signal IP of experimenter's chest time sleepingLDAnd breathe plethysmogram signal VPNTLD, the electricity of experimenter's chest time crouching in right side Impedance digital signal IPRDAnd breathe plethysmogram signal VPNTRD, do linear regression analysis respectively and be designated as: y1=k1x1+b1, y2=k2x2+ b2, y3=k3x3+b3, then k1As the first fixed reference feature value, k2As the second fixed reference feature value, k3As the 3rd fixed reference feature Value;Wherein, y is for breathing plethysmogram signal, and x is electrical impedance digital signal, the parameter produced when b is to do linear regression.And, above-mentioned Step S4 is according to described fixed reference feature value k1, k2, k3Average, be k=(k1+ k2+ k3)/3, then using k as Correction coefficient.It is to say, the present invention is the electrical impedance digital signal of experimenter's chest when acquisition is lain on the back and breathes flow velocity letter Number, the electrical impedance digital signal of experimenter's chest and breathe flow velocity signal and the resistance of experimenter's chest time crouch in right side when lying on the left side After anti-digital signal and breathing flow velocity signal, extract the first fixed reference feature value, the second fixed reference feature value and the 3rd fixed reference feature Value, then calculates the first fixed reference feature value, and the average of the second fixed reference feature value and the 3rd fixed reference feature value carries out not slept The calibration gathering chest breath signal of dormancy posture impact.
The chest breath signal acquisition system not affected by sleeping posture of the present invention, including for gathering experimenter The electrical impedance signal pickup assembly of the electrical impedance signal of chest and for detecting the BIOPAC breathing flow velocity signal of experimenter TSD117, wherein said electrical impedance signal pickup assembly includes power module, constant-current source module, multi-channel switch module, data Acquisition module, signal processing module, exciting electrode and measurement electrode, described constant-current source module is for for measuring electrode offer electric current Excitation, described multi-channel switch module respectively with exciting electrode, measure electrode, constant-current source module and data acquisition module is connected and It is fixed on the exciting current of the exciting electrode of experimenter's chest diverse location for control and receives the voltage signal measuring electrode And the voltage signal received is transferred to data acquisition module, described data acquisition module is according to the voltage signal meter received Calculating the electrical impedance signal of experimenter's chest, described signal processing module is connected with data acquisition module and is used for data acquisition The electrical impedance signal that module transfer comes carry out analog digital conversion and signal is analyzed process, described power module respectively with perseverance Stream source module, multi-channel switch module, data acquisition module and signal processing module electrically connect and are used for carrying out modules Power supply.As it is shown in figure 1, be the structural representation of electrical impedance signal pickup assembly.
When being embodied as, the chest breath signal acquisition method not affected by sleeping posture provided by the present invention can use Experimenter is tested by the chest breath signal acquisition system not affected by sleeping posture as shown in Figure 1.Wherein, described sharp Encourage electrode for chest input stimulus electric current, measure electrode for gathering the voltage magnitude of chest.What the present invention provided is not subject to The chest breath signal acquisition system of sleeping posture impact, is to utilize bio-electrical impedance technology, is subject under back floating position by gathering The breathing flow velocity signal that the electrical impedance signal of the chest of examination person and BIOPAC TSD117 record, to tested under described back floating position The electrical impedance signal of the chest of person carries out analog digital conversion, it is thus achieved that the electrical impedance digital signal of chest when lying on the back;Prone position on the left of collection The breathing flow velocity signal that under gesture, the electrical impedance signal of the chest of experimenter and BIOPAC TSD117 record;To described left side prone position Under gesture, the electrical impedance signal of the chest of experimenter carries out analog digital conversion, it is thus achieved that the electrical impedance digital signal of chest when lying on the left side;Adopt Collect the electrical impedance signal of the chest of experimenter under right lateral position and breathing flow velocity signal that BIOPAC TSD117 records;To institute The electrical impedance signal stating the chest of experimenter under right lateral position carries out analog digital conversion, it is thus achieved that the electrical impedance number of chest time crouching in right side Word signal;Electrical impedance digital signal according to described chest when lying on the back and breathe flow velocity signal, the resistance of chest when lying on the left side Anti-digital signal and breathe the electrical impedance digital signal of chest time crouching in flow velocity signal and right side and breathe flow velocity signal, extracts reference Eigenvalue;According to described fixed reference feature value, the chest breath signal collected described experimenter under different sleeping postures enters Row calibration.The method that the present invention provides is simple, and anti-jamming effectiveness is good, can gather measurement data the most exactly, can be effective Reduce the usage quantity of measuring instrument, simple to operate, it is possible to gather experimenter rapidly and accurately under the influence of not by sleeping posture Chest breath signal, and then realize early stage of some pulmonary disease is detected.
The present invention is described by embodiment, but does not limit the invention, with reference to description of the invention, institute Other changes of disclosed embodiment, as the professional person for this area is readily apparent that, such change should belong to Within the scope of the claims in the present invention limit.

Claims (4)

1. the chest breath signal acquisition method not affected by sleeping posture, it is characterised in that comprise the steps:
S1, respectively gather experimenter lying on the back, lie on the left side and the electrical impedance signal of its chest and BIOPAC under right lateral position The breathing flow velocity signal that TSD117 records;
S2, lie on the back to collect, lie on the left side and under right lateral position, the electrical impedance signal of experimenter's chest carries out analog digital conversion, Obtain respectively and lie on the back, lie on the left side and the electrical impedance digital signal of experimenter's chest time crouch in right side;
S3, lie on the back according to obtain, lie on the left side and the electrical impedance digital signal of experimenter's chest and breathe flow velocity letter time crouch in right side Number, extract fixed reference feature value respectively;
S4, according to the fixed reference feature value obtained, the electrical impedance to the chest that described experimenter collects under different sleeping postures Signal is calibrated;
The concrete operation method of above-mentioned steps S3 is as follows:
S31, according to obtain the electrical impedance digital signal IP of experimenter's chest when lying on the backDDAnd breathe flow velocity signal PNTDD, left side The electrical impedance digital signal IP of experimenter's chest time sleepingLDAnd breathe flow velocity signal PNTLD, the resistance of experimenter's chest time crouching in right side Anti-digital signal IPRDAnd breathe flow velocity signal PNTRD, it is zero by average after filter filtering, then basisIt is calculated the breathing plethysmogram signal VPNT under different sleeping posture respectivelyDD, VPNTLD, VPNTRD;Its In, variable T is time interval;
The electrical impedance digital signal IP of experimenter's chest when S32, basis are lain on the backDDAnd breathe plethysmogram signal VPNTDD, it is subject to when lying on the left side The electrical impedance digital signal IP of examination person's chestLDAnd breathe plethysmogram signal VPNTLD, the electrical impedance number of experimenter's chest time crouching in right side Word signal IPRDAnd breathe plethysmogram signal VPNTRD, do linear regression analysis respectively and be designated as: y1=k1x1+b1, y2=k2x2+b2, y3= k3x3+b3, then k1As the first fixed reference feature value, k2As the second fixed reference feature value, k3As the 3rd fixed reference feature value;Its In, y is for breathing plethysmogram signal, and x is electrical impedance digital signal, the parameter produced when b is to do linear regression.
The chest breath signal acquisition method not affected by sleeping posture, it is characterised in that above-mentioned The concrete operation method of step S1 is as follows:
S11, in two ends up and down constant excitation electrode and the measurement respectively of point of intersection of line and left side midaxillary line of left and right nipple The positive pole of electrode, distinguishes constant excitation electrode at the line of left and right nipple with the two ends up and down of the point of intersection of right side midaxillary line simultaneously With the negative pole measuring electrode;
S12, under experimenter is in back floating position time, clamp nose with nose clip, then record tested by BIOPAC TSD117 Person's breathing flow velocity signal under different sleeping postures, simultaneously by exciting electrode to experimenter's input stimulus electric current;
S13, according to exciting current and measure voltage, calculate experimenter's its chest under different sleeping postures according to Ohm's law Electrical impedance signal.
The chest breath signal acquisition method not affected by sleeping posture, it is characterised in that above-mentioned Step S4 is according to above-mentioned fixed reference feature value k1, k2, k3Average, be k=(k1+ k2+ k3)/3, then using k as Correction coefficient.
4. the chest breath signal acquisition system not affected by sleeping posture, this system is used for any of the above-described claim institute State in the chest breath signal acquisition method not affected by sleeping posture, it is characterised in that include for gathering experimenter's chest The electrical impedance signal pickup assembly of electrical impedance signal and for detecting the BIOPAC TSD117 breathing flow velocity signal of experimenter, Wherein said electrical impedance signal pickup assembly includes power module, constant-current source module, multi-channel switch module, data acquisition module Block, signal processing module, exciting electrode and measurement electrode, described constant-current source module is used for as measuring electrode offer current excitation, Described multi-channel switch module is connected with exciting electrode, measurement electrode, constant-current source module and data acquisition module and is used for respectively Control be fixed on the exciting current of the exciting electrode of experimenter's chest diverse location and receive the voltage signal of measurement electrode and incite somebody to action The voltage signal received is transferred to data acquisition module, and described data acquisition module calculates according to the voltage signal received The electrical impedance signal of experimenter's chest, described signal processing module is connected with data acquisition module and is used for data acquisition module The electrical impedance signal transmitted carry out analog digital conversion and signal is analyzed process, described power module respectively with constant-current source Module, multi-channel switch module, data acquisition module and signal processing module electrically connect and are used for being powered modules.
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CN110213991B (en) * 2017-01-24 2023-10-10 美国亚德诺半导体公司 Multi-sensor device for monitoring health
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