Background technology
Duck viral hepatitis is to be endangered one of the most serious epidemic disease of duckling by what DHV caused, propagate fast, anxious, mortality rate height of falling ill, cut open inspection liver and have obvious petechia and ecchymosis, duckling age in days is more little, mortality rate is more high, most high mortality, up to 90%~95%, often causes heavy economic losses to duckery.
It is " strengthening vital QI to eliminate pathogenic factors " that natural Chinese medicinal herb prevents and treats the mechanism of disease." just " make a comment or criticism gas, namely ensure the normal function of health and eliminate the resistance against diseases of paathogenic factor;" heresy " refers to pathogen, and namely all unhealthful cause physiological dysfunction and virulence factor (containing chemistry, physics and biotic factor).Thus, the mechanism of natural Chinese medicinal herb diseases prevention and health care is to transfer all favorable factors of body, improves immunologic function and defensive enginery, dispeling disease and evil, promotes rehabilitation.At present, treat the antiviral agents of this disease expanded to by heat and toxic materials clearing away medicine have rush down under, wind-damp dispelling, stop blooding, invigorate blood circulation, the medicine of the effect such as qi-restoratives, medicinal herb components is complicated, reaches antivirus action by directly or indirectly two kinds of approach.The determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs relation of virus-body-Chinese medicine three is paid attention in anti virus herb treatment, pathogen in purged body, improve body integrality, strengthened the ability of viral infection resisting by transfer body specificity and non-specific immunity, there is adaptability and superiority widely.
Summary of the invention
Present invention aim to provide a kind of determined curative effect, cure rate is higher, have no side effect, and drug residue free, is not likely to produce drug-fast a kind of Chinese herbal medicine biological preparation preventing and treating poultry disease.
It is an object of the invention to solve by the following technical programs, the Chinese herbal medicine biological preparation of this preventing and treating duck viral hepatitis is made up of the raw material of following parts by weight: Herba Wedeliae Prostratae 3-5 part, Herba hedyotis hispidae (Herba Hedyotidis Auriculariae) 4-6 part, Herba Gentianae Algidae 3-5 part, Herba Anaphalidis Margaritaceae 4-8 part, Caulis et Folium Lini 5-7 part, Fructus Akebiae 5-7 part, Herba Equiseti Hiemalis's 3-9 part, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 5-7 part, Radix seu Fructus Rosae Sericeae 5-7 part, Eriosema himalaicum Ohashi 5-7 part.
Preferably, described Chinese herbal medicine biological preparation is made up of the raw material of following weight portion: Herba Wedeliae Prostratae 4 parts, Herba hedyotis hispidae (Herba Hedyotidis Auriculariae) 5 parts, Herba Gentianae Algidae 4 parts, Herba Anaphalidis Margaritaceae 6 parts, 6 parts of Caulis et Folium Lini, Fructus Akebiae 6 parts, Herba Equiseti Hiemalis 6 parts, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 6 parts, Radix seu Fructus Rosae Sericeae 6 parts, Eriosema himalaicum Ohashi 6 parts.
Preparation method: said herbal medicine dried, weigh, be crushed to 60-80 mesh sieve, puddles uniformly standby.
The cardinal symptom of Duck Hepatitis Virus shows as heating, and the green loose stool of excretion, binocular Guan Bi is in lethargy shape, and before dead, spasmodic tic, corpse are opisthotonus shape;Cut open inspection mainly see hepatomegaly, in khaki or mulberry, surface has point-like, speckle shape or striated hemorrhage.Carrying out dialectical according to traditional Chinese veterinary medicine theory, primary disease is the Liver Channel excess-heat because diseases caused by exogenous pathogenic factor epidemic disease poison causes and diarrhea due to damp-heat card, extreme heat causing wind syndrome, liver-wind stirring up internally, therefore sees the symptoms such as lethargy, tic, opisthotonus, and treatment should heat clearing away solution duck spasmolytic malicious, soothing the liver.
Herba Wedeliae Prostratae, Herba hedyotis hispidae (Herba Hedyotidis Auriculariae) heat-clearing and toxic substances removing;Herba Gentianae Algidae, Herba Anaphalidis Margaritaceae heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire;Caulis et Folium Lini, Fructus Akebiae suppressing the hyperactive liver to relieve the wind syndrome, depressed liver-energy dispersing and QI regulating;Herba Equiseti Hiemalis, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) expelling pathogenic factors from the exterior expels the heat-evil, expelling pathogenic factors from the exterior spasmolytic is dispeled the wind;Radix seu Fructus Rosae Sericeae, Eriosema himalaicum Ohashi digestion-promoting spleen-invigorating, dysentery relieving.The merit of heat-clearing and toxic substances removing, soothing the liver spasmolytic, strengthening the spleen to promote digestion played altogether by all medicines, therefore duck viral hepatitis has good prevention effect.
1. the duckling that individuality duck culturing family, physical data Yinan County is raised, is diagnosed as the sick duck group of Duck Hepatitis Virus, 3~20 ages in days through domestic animal epidemic prevention and quarantine station after morbidity.Test with duck totally 1000 plumage, be divided into Chinese herb prevention group, antibody to prevent and treat group and matched group (not to any medicine).
2. test method Chinese herb prevention group adopts Chinese herbal medicine biological preparation of the present invention, weighs Herba Wedeliae Prostratae 4kg, Herba hedyotis hispidae (Herba Hedyotidis Auriculariae) 5kg, Herba Gentianae Algidae 4kg, Herba Anaphalidis Margaritaceae 6kg, Caulis et Folium Lini 6kg, Fructus Akebiae 6kg, Herba Equiseti Hiemalis 6kg, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 6kg, Radix seu Fructus Rosae Sericeae 6kg, Eriosema himalaicum Ohashi 6kg.Said herbal medicine is dried, weigh, be crushed to 60-80 mesh sieve, puddle uniformly.Used time adds the stewing bubble of certain amount of boiling water 30 minutes or boiling 20 minutes, and extracting juice is for duck drinking-water, medicinal residues spice, and serious sick duck takes concoction and gavages.Dosage every plumage crude drug 3~5g every day, is used in conjunction 3~5 days.Antibody preventing and treating group adopts Duck Hepatitis Virus high immunity yolk antibody, Jiangxi biologics maker produce, it is recommended that therapeutic dose is leg muscle injection 1ml of every plumage.Matched group is method for breeding routinely.
3. test is observed its incidence, clinical symptoms, necropsy change, dead quantity etc. with duck by result of the test.Result is in Table 1.Between three groups, mortality rate has significant difference.
Table 1. Chinese herbal medicine biological preparation prevents and treats the effectiveness comparison of Duck Hepatitis Virus with high immunity yolk antibody