CN104062292B - A kind of manufacture method of all solid state visualization taste sensor array - Google Patents
A kind of manufacture method of all solid state visualization taste sensor array Download PDFInfo
- Publication number
- CN104062292B CN104062292B CN201410313571.0A CN201410313571A CN104062292B CN 104062292 B CN104062292 B CN 104062292B CN 201410313571 A CN201410313571 A CN 201410313571A CN 104062292 B CN104062292 B CN 104062292B
- Authority
- CN
- China
- Prior art keywords
- visualization
- sensor array
- sensitive material
- microporous membrane
- taste
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The manufacture method of a kind of all solid state visualization taste sensor array of the present invention, belongs to the manufacture method technical field of sensor array.First select trace level chemical substance in fluid sample is had the hydrophobic porphyrins of color response, phthalocyanine-like compound as visualization sensitive material, select hydrophilic mixed cellulose ester microporous membrane, hydrophobicity ABS plastic thin plate (acrylonitrile butadient styrene), waterproof double faced adhesive tape as substrate manufacture material.Take on the mixed cellulose ester microporous membrane that 0.1 10 μ L visualization sensitive material solution are fixed on substrate in aperture by trace sampling apparatus, an aperture fixing one visualization sensitive material, then obtain chloroform after drying visualizing taste sensor array.The all solid state visualization taste sensor array of the present invention has that expense is low, accuracy of detection is high, concordance advantages of higher between detection range width, length in service life, different batches.
Description
Technical field
The invention belongs to the manufacture method technical field of sensor array, refer in particular to a kind of all solid state visualization taste sensor
The manufacture method of array.
Background technology
Taste sensor is referred to as electronic tongues, and because having, response time is short, detection speed is fast, highly sensitive, detection knot
The advantage such as really error is little, reproducible, has broad application prospects in the field such as food quality detection, environmental monitoring.But,
Current existing taste sensor be mainly based upon transmembrane potential analytic process, electrochemical process (voltammetry, conductance method, potentiometric method etc.),
The methods such as photoelectric method, their common drawback is sensor production complex steps, relatively costly, finished product is expensive.
Numerous studies show, owing to porphyrin, phthalocyanine-like compound have big pi-conjugated circulus and rigid planar structure,
Have chromophore, hydrogen bond, axial coordination, electrostatic interaction equimolecular Interaction Force and tested microchemistry thing can be passed through
Matter generation effect so that porphyrin, phthalocyanine-like compound molecular configuration change, thus produce color change and i.e. visualize, logical
Cross the detection that this color is changed, just can reach the purpose that measured matter is detected.Existing report based on porphyrin,
The visible sensor array of phthalocyanine-like compound, such as " Food Chemistry " (" Food Chemistry ") 2014 volume 145
Page 639 645 " Artificial Olfactory based on visible sensor array and the sense of taste are to the Chinese green tea of different cultivars and grade
Distinguish (Discrimination of Chinese green tea according to varieties and grade
Levels using artificial nose and tongue based on colorimetric sensor arrays) "
One literary composition, use hydrophobicity polyvinylidene difluoride film (PVDF membrane) as the baseplate material of visible sensor array, this
The sensitivity in fluid sample detects of the visible sensor array can be greatly reduced.Because, the chemical substance in aqueous solution
Fully cannot react with the sensitive material invaded in polyvinylidene difluoride film.Furthermore, the visualization of document report
The preparation process of sensor array is numerous and diverse, need special test operation personnel, and the longest.
Summary of the invention:
For overcoming the deficiencies in the prior art, the present invention proposes the making side of a kind of all solid state visualization taste sensor array
Method, made visualization taste sensor array not only expense is low, accuracy of detection is high, detection range width, and length in service life,
Between different batches, concordance is high.
The manufacture method of a kind of all solid state sense of taste visible sensor array of the present invention is as follows:
(1) selection of sensitive material is visualized: select that trace level chemical substance in fluid sample is had color response and dredge
Water-based free radical porphyrin, metalloporphyrin and phthalocyanine-like compound are as visualization sensitive material.
(2) selection of solvent: select chloroform as solvent, visualization sensitive material is configured to the solution of 1-10mM.
(3) selection of sensor base plate material: select hydrophilic mixed cellulose ester microporous membrane, hydrophobicity ABS thin plate
(acrylonitrile-butadiene-styrene copolymer), waterproof double faced adhesive tape make material as sensor base plate.
(4) making of sensor base plate: first ABS plastic thin plate is processed into the length with several diameter 2-5mm apertures
Rectangular block, then mixed cellulose ester microporous membrane is fixed between two ABS plastic thin plates with waterproof double faced adhesive tape, in operation
Allow the apertures align on the two sheet plastic so that in hole, mixed cellulose ester microporous membrane can come out.
(5) take 0.1-10 μ L visualization sensitive material solution by trace sampling apparatus and be fixed to mixing in aperture on substrate
On condensating fiber element ester microporous membrane, an aperture fixing one visualization sensitive material, then chloroform is obtained after drying visual
Change taste sensor array.
This all solid state sense of taste visible sensor array has a following characteristics:
(1) porphyrin, phthalocyanine-like compound developer in all solid state sense of taste visible sensor array developed have
Significantly molecule distinguishability and coloring function, and due to their hydrophobicity thus significantly reduce in fluid sample a large amount of
The water the existed impact on sensor, drastically increases the detection sensitivity of sensor.
(2) all solid state sense of taste visible sensor array developed selects hydrophilic cellulose mixture ester film, dredges
Aqueous ABS plastic plate is as baseplate material.Due to the hydrophilic of mixed cellulose ester makes the chemical substance in fluid sample can
Sufficiently to react with visualization sensitive material, thus can greatly improve the detection sensitivity of sensor.Hydrophobicity ABS
The use of sheet plastic is that successive image acquisition is provided convenience, it is ensured that the concordance of testing result.
(3) by elaborate sensor base plate, the concordance of sense of taste visible sensor is greatly improved, uses
Life-span have also been obtained raising.
(4) all solid state sense of taste visible sensor array developed is arranged by the chemical-sensitive material of multiple Various Functions
Row combination, greatly extends the range of application of sense of taste visible sensor array.
(5) all solid state sense of taste visible sensor array making step developed is simple, and cost is the lowest.
Accompanying drawing illustrates:
The all solid state sense of taste visible sensor array schematic diagram A(top view that Fig. 1 is developed)；Wherein, 1-ABS plastics are thin
Plate, 2-sense of taste visible sensor, 3-mixed cellulose ester microporous membrane, the waterproof double faced adhesive tape of 4-.
The all solid state sense of taste visible sensor array schematic diagram B(side view that Fig. 2 is developed)；Wherein, 1-ABS plastics are thin
Plate, 2-sense of taste visible sensor, 3-mixed cellulose ester microporous membrane, the waterproof double faced adhesive tape of 4-.
The all solid state sense of taste visible sensor array that Fig. 3 is developed distinguishes the aqueous solution of five kinds of taste compounds of 0.01M
(acid-hydrochloric acid, sweet-glucose, hardship-quinin hydrochloride, salty-sodium chloride, fresh-sodium glutamate) discriminant analysis result figure.
Detailed description of the invention
Below in conjunction with the accompanying drawings all solid state sense of taste visible sensor array making method of the present invention is done in more detail
Description:
(1) selection of all solid state sense of taste quick material of visible sensor color: select trace level chemical substance in fluid sample
There is the hydrophobic porphyrins compounds of color response as the quick material of sensor color.Through repeatedly trial test, finally have selected
Tetraphenylporphyrin, 5,10,15,20-tetraphenyl-porphin manganese chloride, 2,3,7,8,12,13,17,18-octaethyl-porphin chlorination
Manganese, 5,10,15,20-tetraphenyl-porphin copper, 5,10,15,20-tetraphenyl-porphin zinc, 5,10,15,20-tetra-(pentafluorophenyl group)-
Porphyrin iron chloride, 5,10,15,20-tetraphenyl-porphin iron chloride, 5,10,15,20-tetraphenyl-porphin cobalt and 2,3,9,10,
16,17,23,24-eight (octyloxy)-Phthalocyanine Zinc is as the quick material of color of sense of taste visible sensor array.
(2) selection of solvent: select chloroform as the solvent of the quick material of color, weigh porphyrin, phthalocyanine-like compound 10mg molten
Solution in the chloroform of 5mL, 9 kinds of porphyrins, phthalocyanine-like compound molar concentration in the range of 1-10mM.
(3) selection of sensor array substrate material and making: 1. select ABS plastic thin plate 1, mixed cellulose ester taste pore
ABS thin plate, as the baseplate material of sense of taste visible sensor array, is first processed into rectangle by thin film 4, waterproof double faced adhesive tape 3
Square (29mm × 22mm)；2. on Rectangular boxes, uniformly make a call to the aperture of 9 (3 × 3) a diameter of 4mm；3. will mixing fibre
Dimension element ester microporous membrane is clipped between two panels ABS thin plate, and fixing with water proofing property double faced adhesive tape 3, allows on ABS thin plate in operating process
Apertures align so that mixed cellulose ester microporous membrane can come out (as depicted in figs. 1 and 2).
(4) array makes: take, with 10 μ L microscale samplers, the substrate that in 5 μ L steps 2, the solution point of preparation prepares to step 3
On cellulose mixture ester film on aperture, just obtain sense of taste visible sensor 2, each aperture point quick material of one color, just
Obtain sense of taste visible sensor array.
Fig. 3 distinguishes five kinds of taste compounds of 0.01 M by all solid state sense of taste visible sensor array that the present invention is developed
Aqueous solution (acid-hydrochloric acid, sweet-glucose, hardship-quinin hydrochloride, salty-sodium chloride, fresh-sodium glutamate) discriminant analysis result figure.
As can be seen from the figure all solid state sense of taste visible sensor array developed can be to the water of five kinds of taste compounds of low concentration
Solution is made and being accurately distinguished, and shows that developed sensor is effective.
Claims (1)
1. a manufacture method for all solid state visualization taste sensor array, is characterized in that carrying out as steps described below:
(1) selection of sensitive material is visualized: select the hydrophobicity that trace level chemical substance in fluid sample is had color response
Porphyrin, phthalocyanine-like compound are as visualization sensitive material；
(2) selection of solvent: select chloroform as solvent, visualization sensitive material is configured to the solution of 1-10mM；
(3) selection of sensor base plate material: select hydrophilic mixed cellulose ester microporous membrane, hydrophobicity ABS thin plate (third
Alkene nitrile-BS), waterproof double faced adhesive tape make material as sensor base plate；
(4) making of sensor base plate: be first processed into by ABS plastic thin plate with several a diameter of 2-5mm apertures is rectangular
Shape square, then mixed cellulose ester microporous membrane is fixed between two ABS plastic thin plates with waterproof double faced adhesive tape, operation allows
Apertures align on two ABS plastic thin plates so that in hole, mixed cellulose ester microporous membrane can come out；
(5) take, by trace sampling apparatus, the mixing fibre that 0.1-10 μ L visualization sensitive material solution is fixed on substrate in aperture
On dimension element ester microporous membrane, an aperture fixing one visualization sensitive material, then obtain chloroform after drying visualizing taste
Sense sensor array；
Wherein said porphyrins is hydrophobicity free radical porphyrin and metalloporphyrin, and phthalocyanine-like compound is hydrophobic metals
Phthalocyanine；
Wherein said mixed cellulose ester microporous membrane aperture is 0.15-8 μm；
Wherein said ABS plastic lamella thickness is 0.2-2mm；
The wherein said Rectangular boxes that is processed into is 2-5cm2。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410313571.0A CN104062292B (en) | 2014-07-03 | 2014-07-03 | A kind of manufacture method of all solid state visualization taste sensor array |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410313571.0A CN104062292B (en) | 2014-07-03 | 2014-07-03 | A kind of manufacture method of all solid state visualization taste sensor array |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104062292A CN104062292A (en) | 2014-09-24 |
| CN104062292B true CN104062292B (en) | 2016-08-17 |
Family
ID=51550107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410313571.0A Active CN104062292B (en) | 2014-07-03 | 2014-07-03 | A kind of manufacture method of all solid state visualization taste sensor array |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104062292B (en) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106596531B (en) * | 2016-11-21 | 2019-08-27 | 江苏大学 | A kind of method and device detecting volatile organic compounds |
| CN106584477A (en) * | 2016-12-22 | 2017-04-26 | 陈卫涛 | Feeding device |
| CN106619138A (en) * | 2016-12-22 | 2017-05-10 | 陈卫涛 | Feeding device |
| CN107389671A (en) * | 2017-07-05 | 2017-11-24 | 江苏大学 | A kind of visualization sense of taste, the preparation method of smell merge sensor |
| CN109447130B (en) * | 2018-09-30 | 2021-10-12 | 江苏大学 | Ha-bai preserved meat detection device and method based on visual gas-sensitive array |
| CN109959652B (en) * | 2018-12-26 | 2022-03-18 | 云南中烟工业有限责任公司 | Method for evaluating taste change of high static pressure induced Maillard reaction product |
| CN109959653B (en) * | 2018-12-26 | 2022-03-18 | 云南中烟工业有限责任公司 | Bionic array sensor-based plant extract taste measurement method |
| CN110426388A (en) * | 2019-08-13 | 2019-11-08 | 宿州学院 | Reduce the visualization taste sensor component and production method of random error |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2035813B1 (en) * | 2006-06-16 | 2012-06-06 | Sony DADC Austria AG | Optical sensor and method for indicating the age or quality of a natural product |
| CN101074931B (en) * | 2007-06-27 | 2010-05-19 | 江苏大学 | Production of color-sensitive gas sensor array |
| CN101762571B (en) * | 2009-12-30 | 2013-07-10 | 东南大学 | Flow-type gas sensor array and preparation method thereof |
| CN102507550B (en) * | 2011-10-20 | 2013-11-20 | 江苏大学 | Manufacturing method of food odor visible sensor based on natural pigment |
| CN102967597A (en) * | 2012-09-26 | 2013-03-13 | 江苏大学 | Olfactory imaging sensing technology based yellow wine storage time identification method and identification system |
| CN103674946B (en) * | 2013-12-18 | 2016-09-14 | 东南大学 | Color-sensitive gas sensor array based on the enrichment of nanofiber gas and preparation method thereof |
-
2014
- 2014-07-03 CN CN201410313571.0A patent/CN104062292B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN104062292A (en) | 2014-09-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104062292B (en) | A kind of manufacture method of all solid state visualization taste sensor array | |
| CN106518895B (en) | Based on simultaneously encapsulate target substance and synthesize with redox active MOFs preparation method | |
| Bakker | Electroanalysis with membrane electrodes and liquid–liquid interfaces | |
| CN107389671A (en) | A kind of visualization sense of taste, the preparation method of smell merge sensor | |
| Dechtrirat et al. | An electrochemical MIP sensor for selective detection of salbutamol based on a graphene/PEDOT: PSS modified screen printed carbon electrode | |
| CN104181215B (en) | The preparation of a kind of electropolymerization molecularly imprinted polymer hollow channel paper device and the application in pesticide residues detect immediately | |
| Prasad et al. | Molecularly imprinted polymer (biomimetic) based potentiometric sensor for atrazine | |
| Silva-Neto et al. | Plug-and-play assembly of paper-based colorimetric and electrochemical devices for multiplexed detection of metals | |
| Dossi et al. | A cotton thread fluidic device with a wall-jet pencil-drawn paper based dual electrode detector | |
| Lian et al. | A highly selective melamine sensor relying on intensified electrochemiluminescence of the silica nanoparticles doped with [Ru (bpy) 3] 2+/molecularly imprinted polymer modified electrode | |
| CN110297025B (en) | Nano-scale Ni-Fe Prussian blue analogue material, preparation method thereof and application of nano-scale Ni-Fe Prussian blue analogue material in electrochemical detection of o-nitrophenol | |
| Sedaghat et al. | Development of a nickel oxide/oxyhydroxide-modified printed carbon electrode as an all solid-state sensor for potentiometric phosphate detection | |
| Tan et al. | An electrochemical sensor for the determination of phoxim based on a graphene modified electrode and molecularly imprinted polymer | |
| CN106323893A (en) | Palladium-ion multi-channel response probe and synthesis method and application thereof | |
| Fouladgar et al. | A novel optical chemical sensor for thallium (III) determination using 4-(5-bromo-2-pyridylazo)-5-(diethylamino)-phenol | |
| CN104237217B (en) | A kind of various trace heavy metal ion Simultaneous Detections based on visualization technique | |
| Giordano et al. | Bifunctional metal meshes acting as a semipermeable membrane and electrode for sensitive electrochemical determination of volatile compounds | |
| Song et al. | A disposable cobalt-based phosphate sensor based on screen printing technology | |
| CN103675050A (en) | Methyl-parathion molecularly-imprinted electrochemical sensor and preparation method thereof | |
| Mahmoudi et al. | A disposable paper-based microfluidic electrochemical cell equipped with graphite-supported gold nanoparticles modified electrode for gallic acid determination | |
| Cancelliere et al. | Nafion-based label-free immunosensor as a reliable warning system: The case of AFB1 detection in cattle feed | |
| Rho et al. | Sensitivity-tunable and disposable ion-sensing platform based on reverse electrodialysis | |
| Ertürün et al. | A calix [4] arene derivative-doped perchlorate-selective membrane electrodes with/without multi-walled carbon nanotubes | |
| CN103713035B (en) | The electrochemical detection method of okadaic acid in shellfish | |
| CN102353707B (en) | Cholesterol molecule blotting membrane sensing electrode and use of cholesterol molecule blotting membrane sensing electrode in waste oil detection |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |