CN104014056B - A kind of preparation method of injection with low resistance - Google Patents
A kind of preparation method of injection with low resistance Download PDFInfo
- Publication number
- CN104014056B CN104014056B CN201410269437.5A CN201410269437A CN104014056B CN 104014056 B CN104014056 B CN 104014056B CN 201410269437 A CN201410269437 A CN 201410269437A CN 104014056 B CN104014056 B CN 104014056B
- Authority
- CN
- China
- Prior art keywords
- core bar
- overcoat
- injection
- low resistance
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
The invention discloses a kind of preparation method of injection with low resistance.This injection with low resistance comprises core bar and overcoat.Core bar and overcoat are prepared from through extruding pipe processing technique by polymethyl methacrylate.Wherein, overcoat adopts the internal circular surfaces of vacuum mill pressure technology mill pressure overcoat to make the trueness error of the full circle degree of its inner circle be not more than 5 microns.Core bar adopts the method for quick politef steam overlay film to be covered with at the outer round surface of core bar the polytetrafluoroethylene film that a layer thickness is no more than 5 microns after adopting the outer round surface of heating power peripheral milling pressure technology mill pressure core bar to make the trueness error of the full circle degree of its cylindrical be not more than 5 microns again.Injection with low resistance preparation method of the present invention does not produce the chip polluting medicinal liquid, and the initial push-and-pull resistance of injection with low resistance to be produced by preparation method of the present invention can reach and is no more than 0.5N, sliding push-pull resistance can reach and be no more than 0.3N, meets the requirement of clinical practice.
Description
Technical field
The present invention relates to medical injection with low resistance.
Background technology
Disposable sterilized syringe is the most frequently used medical apparatus and instruments, the overcoat injection molding of disposable sterilized syringe, by the impact of material behavior, during product stripping, overcoat must with certain tapering, simultaneously by the impact of temperature, the error of the inner headed face full circle degree of overcoat can reach 0.2-0.25mm, in use can only utilize on core bar and fill rubber piston, overcomes the not tight problem of adaptation that injection molding deformation error brings by the elasticity of rubber piston.And the push-and-pull resistance to sliding between rubber piston and plastic wrapper can only rely on and piston sprays silicone oil as lubricant and solve, synthetic rubber piston, lubricant to the readily oxidizable substance of disposable sterilized syringe, cleannes, acid-base value, the technical specification such as extracting metals content can bring a certain amount of negative effect, also can bring application risk.Simultaneously the size of the quantity for spray of silicone oil, spray area number have direct feel to affect on the sliding capability during the routine of disposable sterilized syringe uses.
According to YY0321.1 " single use anesthetic puncture bag " product standard appendix C, select in appliance configuration table configure 1 injection with low resistance to anesthesia packet, in the anesthesia packet of current nationwide, the injection with low resistance of conventional configuration is all-glass syringe.Hospital in Clinical practice and factory in process of production all-glass syringe have a lot of weak point: complex manufacturing, substandard products are more, cost is higher, efficiency is low, and use Buddha's warrior attendant powder in production and processing, glass powder has very large pollution to product inwall, the risk polluting medicinal liquid also can be brought to Clinical practice in less cleaning position; Easily broken in transportation, be also easy to because all-glass syringe is broken and anesthesia packet can not be used.
Summary of the invention
Problem to be solved by this invention comprises:
1. abandon the air-tightness that rubber piston or sprayed silicon wet goods means reduce the resistance to sliding between overcoat and core bar and improve between overcoat and core bar, purely pass through to improve the resistance to sliding between the precision solution overcoat of processing technique and core bar and airtight performance issue, thus avoid the security risks by rubber piston or the generation of spraying silicone oil.
2. occur material chips in processing technique, cleaning not exclusively causes the contaminated problem of medicinal liquid.
For solving the problem, the scheme that the present invention adopts is as follows:
A preparation method for injection with low resistance, described injection with low resistance comprises core bar and overcoat; Described core bar is tubular body, and one end of described core bar has datum plane, and the other end is provided with core bar by hands; Described overcoat is tubular body, and be enclosed within outside described core bar, one end of described overcoat is provided with conehead, and another section is provided with crimping; Described core bar and overcoat are prepared from through extruding pipe processing technique by polymethyl methacrylate; The preparation method of this injection with low resistance comprises the finishing step of core bar and the finishing step of overcoat; Wherein, the finishing step of described overcoat comprises:
S11: the internal circular surfaces adopting vacuum pump mill pressure technology mill pressure overcoat;
S13: install conehead and crimping on the coat by solder technology;
The finishing step of described core bar comprises:
S21: the outer round surface adopting heating power peripheral milling pressure technology mill pressure core bar, and press through in journey at mill the datum plane processing core bar;
S23: install core bar by hands on core bar by solder technology.
Further, after described step S21, also step S22 is comprised: be placed on by core bar in annular seal space and adopt the method for quick politef steam overlay film to be covered with at the outer round surface of core bar the polytetrafluoroethylene film that a layer thickness is no more than 5 microns.
Further, after described step S11, also step S12 is comprised: be placed on by overcoat in annular seal space and adopt the method for quick politef steam overlay film to be covered with at the internal circular surfaces of overcoat the polytetrafluoroethylene film that a layer thickness is no more than 5 microns.
Further, described solder technology is ultrasonic welding technique.
Further, described solder technology is that heating power grinds molded technology.
Further, described step S11 makes the trueness error of the full circle degree of the internal circular surfaces of overcoat be not more than 5 microns.
Further, described step S21 makes the trueness error of the full circle degree of the outer round surface of core bar be not more than 5 microns.
Further, in described step S21 during heating power peripheral milling pressure technology mill pressure, be 220-260 DEG C for grinding the mill press mill pinch roller temperature of pressure.
Technique effect of the present invention is as follows:.
1, core bar of the present invention and overcoat are prepared from through extruding pipe processing technique by polymethyl methacrylate, and compared to injection molding process, this technique can avoid the chip produced during the injection moulding demoulding, thus avoids the problem of debris contamination.Meanwhile, smooth, smooth, the zero draft of the overcoat inner circle that is prepared from of extruding pipe processing technique.The core bar cylindrical that extruding pipe processing technique is prepared from is smooth, smooth, zero draft.
2, the internal circular surfaces of overcoat is through vacuum mill pressure technology mill pressure, makes the trueness error of the full circle degree of the internal circular surfaces of overcoat be not more than 5 microns; The outer round surface of core bar adopts heating power peripheral milling pressure technology mill pressure to make the trueness error of the full circle degree of the outer round surface of core bar be not more than 5 microns.Resistance to sliding between high-precision processing technique solution overcoat and core bar and airtight performance issue.
3, the internal circular surfaces of overcoat is when vacuum mill pressure technology mill pressure, does not produce chip.
4, when the outer round surface of core bar adopts heating power peripheral milling pressure technology mill to press, because grinding tool is in the condition of high temperature, can not produce chip, even if produce chip, the chip of generation also can by grinding tool melting.
5, the quick politef steam overlay film of core bar and overcoat carries out in annular seal space, and after overlay film, gaseous state politef condenses in the internal circular surfaces of core bar outer round surface or overcoat, can not leave the pollution that chip causes core bar and overcoat.
6, by the above, of the present invention can not produce chip in steps, decrease the step of cleaning, it also avoid the security risks that chip produces the pollution of medicinal liquid.
7, the internal circular surfaces of overcoat and the outer round surface of core bar have one deck polytetrafluoroethylene film, reduce the resistance to sliding between overcoat inner circle and core bar cylindrical, the initial push-and-pull resistance of the injection with low resistance that preparation in accordance with the present invention obtains can reach and be no more than 0.5N, sliding push-pull resistance can reach and be no more than 0.3N, meets clinical practice.
Accompanying drawing explanation
Fig. 1 is the perspective view of injection with low resistance of the present invention.
Fig. 2 is the core bar structure schematic diagram of injection with low resistance of the present invention.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is described in further details.
Injection with low resistance prepared by the present invention, as shown in Figure 1, 2, comprises core bar 2 and overcoat 1.Core bar 2 is tubular body, and one end of core bar 2 has datum plane 21, and the other end is provided with core bar by hands 22.Overcoat 1 is tubular body, is enclosed within outside core bar 2, and one end of overcoat 1 is provided with conehead 11, and another section is provided with crimping 12.Core bar 2 and overcoat 1 are prepared from through extruding pipe processing technique by polymethyl methacrylate (PMMA).The present invention is the polymethyl methacrylate of medical grade for the preparation of the polymethyl methacrylate of core bar 2 and overcoat 1.
Above-mentioned injection with low resistance is prepared by following steps: carry out polish to core bar 2 and overcoat 1 first respectively, then according to the standard-required of GB15810 " disposable sterilized syringe ", stamp the containing mark lines such as zero graduation line, scale division line, nominal capacity graduation mark, total capacity graduation mark at the outer round surface of overcoat after, last core bar 2 is inserted in overcoat 1 and is assembled into finished product packing.
Wherein, the polish of overcoat 1 comprises the following steps: first, step S11, adopt vacuum mill pressure technology mill to press the internal circular surfaces of the overcoat 1 be prepared from through extruding pipe processing technique by polymethyl methacrylate, after mill pressure, make the trueness error of the full circle degree of the internal circular surfaces of overcoat 1 be not more than 5 microns.Vacuum mill pressure technology refers to the metal tube adapted with overcoat 1 internal diameter size overcoat 1 liner one, by heating, overcoat is softened the inwall of overcoat 1, by being attached on metal tube by the inwall of negative pressure of vacuum by overcoat 1.Then be step S13, utilize ultrasonic bonding molding that conehead 11 and crimping 12 are arranged on the two ends of overcoat 1.Ultrasonic bonding forming technique in step S13 also can grind molded replacement with heating power.
Wherein, the polish of core bar 2 comprises the following steps: first, step S21: the outer round surface adopting heating power peripheral milling pressure technology mill pressure core bar 2, make the trueness error of the full circle degree of the outer round surface of core bar 2 be not more than 5 microns after mill pressure, and grind the datum plane 21 of disposable processing core bar in pressing formation process.Here, heating power peripheral milling pressure technology refers to that the mill pinch roller of the mill press of the outer round surface for grinding pressure core bar 2 is heated, and the temperature of mill pinch roller controls at 220-260 DEG C.Then be step S23, utilize ultrasonic bonding forming technique to be arranged on core bar 2 by hands 22 by core bar.Ultrasonic bonding forming technique in step S23 also can grind molded replacement with heating power.
On this external above-mentioned basis, can also at the ultra-thin politef of internal circular surfaces vacuum covering one deck of the outer round surface of core bar 2 and/or overcoat 1.When the politef that outer round surface vacuum covering one deck of core bar 2 is ultra-thin, namely after step S21, increase step S22: be placed in annular seal space by core bar 2 and adopt the method for quick politef steam overlay film to be covered with at the outer round surface of core bar 2 polytetrafluoroethylene film that a layer thickness is no more than 5 microns.When the internal circular surfaces of overcoat 1 lays the ultra-thin politef of one deck, namely after step S11, increase step S12: be placed in annular seal space by overcoat 1 and adopt the method for quick politef steam overlay film to be covered with at the internal circular surfaces of overcoat 1 polytetrafluoroethylene film that a layer thickness is no more than 5 microns.In step S12 and step 22, the method of quick politef steam overlay film refers to the politef steam forming 410 DEG C after politef heating and gasifying, politef steam is placed in an annular seal space, and then namely overcoat 1 or core bar 2 complete surface coating quickly through sealing chamber.Because politef steam is in high temperature state, and be in normal-temperature by the overcoat 1 of annular seal space or core bar 2, when politef steam runs into the outer round surface of the internal circular surfaces of overcoat 1 or core bar 2, what make the outer round surface of the internal circular surfaces of overcoat 1 or core bar 2 is in semi-molten state, thus politef steam is melted mutually with the polymethyl methacrylate of the internal circular surfaces of overcoat 1 or the outer round surface of core bar 2, when overcoat 1 or core bar 2 cool, form the ultra-thin polytetrafluoroethylene film of one deck at the internal circular surfaces of overcoat 1 or the outer round surface of core bar 2.The characteristic having a low-friction coefficient due to politef decreases the resistance to sliding of the internal circular surfaces of overcoat 1 or the outer round surface of core bar 2.
It should be noted that, after being covered with the ultra-thin polytetrafluoroethylene film of one deck through the outer round surface of core bar 2 and the internal circular surfaces of overcoat 1, after tested, the initial push-and-pull resistance of this injection with low resistance can reach and be no more than 0.5N, and sliding push-pull resistance can reach and be no more than 0.3N.
Claims (8)
1. a preparation method for injection with low resistance, described injection with low resistance comprises core bar and overcoat; Described core bar is tubular body, and one end of described core bar has datum plane, and the other end is provided with core bar by hands; Described overcoat is tubular body, and be enclosed within outside described core bar, one end of described overcoat is provided with conehead, and another section is provided with crimping; It is characterized in that, described core bar and overcoat are prepared from through extruding pipe processing technique by polymethyl methacrylate; The preparation method of this injection with low resistance comprises the finishing step of core bar and the finishing step of overcoat; Wherein, the finishing step of described overcoat comprises:
S11: the internal circular surfaces adopting vacuum mill pressure technology mill pressure overcoat;
S13: install conehead and crimping on the coat by solder technology;
The finishing step of described core bar comprises:
S21: the outer round surface adopting heating power peripheral milling pressure technology mill pressure core bar, and press through in journey at mill the datum plane processing core bar;
S23: install core bar by hands on core bar by solder technology.
2. the preparation method of injection with low resistance as claimed in claim 1, it is characterized in that, after described step S21, also comprise step S22: core bar is placed in annular seal space and adopts the method for quick politef steam overlay film to be covered with at the outer round surface of core bar the polytetrafluoroethylene film that a layer thickness is no more than 5 microns.
3. the preparation method of injection with low resistance as claimed in claim 1 or 2, it is characterized in that, after described step S11, also comprise step S12: overcoat is placed in annular seal space and adopts the method for quick politef steam overlay film to be covered with at the internal circular surfaces of overcoat the polytetrafluoroethylene film that a layer thickness is no more than 5 microns.
4. the preparation method of injection with low resistance as claimed in claim 1, it is characterized in that, described solder technology is ultrasonic welding technique.
5. the preparation method of injection with low resistance as claimed in claim 1, it is characterized in that, described solder technology replaces with heating power and grinds molded technology.
6. the preparation method of injection with low resistance as claimed in claim 1, it is characterized in that, described step S11 makes the trueness error of the full circle degree of the internal circular surfaces of overcoat be not more than 5 microns.
7. the preparation method of injection with low resistance as claimed in claim 1, it is characterized in that, described step S21 makes the trueness error of the full circle degree of the outer round surface of core bar be not more than 5 microns.
8. the preparation method of injection with low resistance as claimed in claim 1, is characterized in that, in described step S21 during heating power peripheral milling pressure technology mill pressure, is 220-260 DEG C for grinding the mill press mill pinch roller temperature of pressure.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410269437.5A CN104014056B (en) | 2014-06-17 | 2014-06-17 | A kind of preparation method of injection with low resistance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410269437.5A CN104014056B (en) | 2014-06-17 | 2014-06-17 | A kind of preparation method of injection with low resistance |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104014056A CN104014056A (en) | 2014-09-03 |
| CN104014056B true CN104014056B (en) | 2015-11-25 |
Family
ID=51431232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410269437.5A Active CN104014056B (en) | 2014-06-17 | 2014-06-17 | A kind of preparation method of injection with low resistance |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104014056B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106689114B (en) * | 2017-01-05 | 2021-12-07 | 卞陆杰 | Method for making unhaired vertebrate animal specimen and used injector |
| EP3862153B1 (en) * | 2018-10-04 | 2023-09-27 | Mitsubishi Gas Chemical Company, Inc. | Multilayer syringe barrel manufacturing method |
| CN110786984B (en) * | 2019-11-04 | 2022-06-07 | 上海康德莱企业发展集团股份有限公司 | Special silicone oil-free injector for ophthalmology |
| CN111374735A (en) * | 2020-03-30 | 2020-07-07 | 郑州大学第一附属医院 | Thrombus suction device |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1115973A (en) * | 1993-11-03 | 1996-01-31 | 勃勒柯国际有限公司 | Method for the preparation of pre-filled plastic syringes |
| CN101146561A (en) * | 2005-01-21 | 2008-03-19 | 艾凡卡医学设备公司 | Reciprocating procedure syringes |
| CN102068733A (en) * | 2009-12-31 | 2011-05-25 | 山东省药用玻璃股份有限公司 | High-cleanness pre-filled syringe |
-
2014
- 2014-06-17 CN CN201410269437.5A patent/CN104014056B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1115973A (en) * | 1993-11-03 | 1996-01-31 | 勃勒柯国际有限公司 | Method for the preparation of pre-filled plastic syringes |
| CN101146561A (en) * | 2005-01-21 | 2008-03-19 | 艾凡卡医学设备公司 | Reciprocating procedure syringes |
| CN102068733A (en) * | 2009-12-31 | 2011-05-25 | 山东省药用玻璃股份有限公司 | High-cleanness pre-filled syringe |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104014056A (en) | 2014-09-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104014056B (en) | A kind of preparation method of injection with low resistance | |
| CN105500561A (en) | Gasket for prefilled syringe | |
| AU2020201401B2 (en) | Three-position plungers, film coated plungers and related syringe assemblies | |
| JP5717593B2 (en) | Mold for molding gasket for prefilled syringe | |
| CN104941039B (en) | Prefilled syringe gasket and its manufacturing method | |
| JP4847632B1 (en) | Medical stopper surface-coated skived film, medical stopper using the film, prefilled syringe using the stopper, and method for producing the film | |
| CN108261588B (en) | Medical device, assembly comprising a medical device and method of manufacturing a medical device | |
| JP2016532469A (en) | Switchable plunger, film-coated plunger and associated syringe assembly | |
| MX2014008819A (en) | Device with co-molded closure, one-way valve, variable-volume storage chamber and anti-spritz feature and related method. | |
| CN101433740A (en) | Sealing cover for large infusion plastic bottle and plastic bag and matching bottle stopper puncture device | |
| CN107684647A (en) | Medical syringe, sealing gasket and its manufacture method | |
| JP2011062518A (en) | Method of producing stopper | |
| JP5602754B2 (en) | Syringe and syringe body manufacturing apparatus and syringe body manufacturing method | |
| CN102423508A (en) | Transfusion conduit of blood transfusion apparatus and preparation method thereof | |
| CN206715043U (en) | A kind of anti-dropout connecting tube | |
| CN103879620B (en) | Chemical liquids holding bottle and manufacture method thereof | |
| CN111070504B (en) | Preparation method of latex catheter mold | |
| CN203694246U (en) | Safety type blow molding dripping bucket module | |
| CN203736609U (en) | Integrated infusion apparatus with built-in drop-weight control head | |
| CN103271822A (en) | Seamless laminated rubber plug and preparation method thereof | |
| CN215652872U (en) | Sputum suction tube with lubricating effect | |
| CN103357085B (en) | A kind of combination cover for transfusion | |
| US20240140652A1 (en) | Processing method of a tube head structure and a product thereof | |
| CN201304099Y (en) | Plastic ampoule packaging with 6% Luer taper | |
| CN205994786U (en) | A kind of medical waste liquid soft bag |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20230801 Address after: 224700 gaozuo Town Industrial Park, Jianhu County, Yancheng City, Jiangsu Province Patentee after: Cai Chaolin Address before: 224752 Gaozuo Industrial Park, Jianhu County, Yancheng City, Jiangsu Province Patentee before: YANCHENG MOISTEN MEDICAL APPLIANCES FACTORY |
|
| TR01 | Transfer of patent right |