CN104000628A - Stomach first-aid capsule haemostat and hemostasis method - Google Patents
Stomach first-aid capsule haemostat and hemostasis method Download PDFInfo
- Publication number
- CN104000628A CN104000628A CN201410194775.7A CN201410194775A CN104000628A CN 104000628 A CN104000628 A CN 104000628A CN 201410194775 A CN201410194775 A CN 201410194775A CN 104000628 A CN104000628 A CN 104000628A
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- reaction
- stomach
- haemostat
- reaction liquid
- capsule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12136—Balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B2017/12004—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for haemostasis, for prevention of bleeding
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- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
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- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Surgical Instruments (AREA)
Abstract
The invention discloses a stomach first-aid capsule haemostat which comprises an elastic air bag. The elastic air bag is tied up with a gastric soluble gelatin band, a reaction liquid containing cavity, a reaction powder containing cavity and at least one free elastic expansion cavity are formed in an inner cavity of the elastic air bag, and the reaction liquid containing cavity, the reaction powder containing cavity and the at least one free elastic expansion cavity are provided with independent spaces. Reaction liquid is stored in the reaction liquid containing cavity, reaction solid is stored in the reaction powder containing cavity, and the reaction solid and the reaction liquid meet and produce a reaction to generate gas to expand the elastic air bag. The invention further discloses a hemostasis method of the stomach first-aid capsule haemostat. A chemical reaction technology with the gas generated and an air bag compressing physical mode are combined to carry out hemostasis, the curative effect is accurate, the stomach first-aid capsule haemostat can be used by a patient at first time to control the bleeding symptom fast, the whole process does not need participation of medical personnel, the patient can save himself, the patient can use the stomach first-aid capsule haemostat simply like oral administration of capsule medicine, no adverse reaction occurs, use is convenient and fast, and precious time can be gained for the patient.
Description
Technical field
The present invention relates to stomach hemostatic technique field, be specifically related to a kind of stomach first aid capsule haemostat and Hemostasis.
Background technology
Upper gastrointestinal hemorrhage is common clinical, often because of the urgency of falling ill, make progress the rapid short time and will cause patient's hemorrhagic shock threat to life.Foreign data demonstration, the patient of upper gastrointestinal hemorrhage accounts for 0.1% of average annual total number of hospitalized, and its case fatality rate approaches 10%.The cause of disease of upper gastrointestinal hemorrhage is a lot, and common is peptic ulcer, and portal hypertension causes esophageal varices, hemorrhagic gastritis and gastric cancer etc.
Have therapeutic endoscopy and a multiple Hemostasis of operative treatment although at present clinical, still have many patients unstable because massive blood loss causes circulating, the many ordinary circumstances of underlying diseases are poor in addition, cannot tolerate emergency operation or therapeutic endoscopy and clinicist is felt simply helpless.Also have in addition part patient because of amount of bleeding large, distant from hospital, at the shock death of just seeking medical advice in way.For this reason, research and develop a kind of convenient and swift, be easy to implement, the Hemostasis of definite effect becomes clinical urgently required.
Summary of the invention
For above-mentioned deficiency, one of the object of the invention is, provides a kind of structural design ingenious, reasonable, easy to use, quick, the stomach first aid capsule haemostat that haemostatic effect is definite.
Two of object of the present invention is, a kind of Hemostasis of aforesaid stomach first aid capsule haemostat is provided.
The present invention for achieving the above object, the technical scheme providing is: a kind of stomach first aid capsule haemostat, it comprises elastic bag, on described elastic bag, tie up gastric solubility gelatin band, make the inner chamber of this elastic bag form reaction liquid container cavity, reaction powder accommodation cavity and at least one free elastic expansion chamber with separate space, in described reaction liquid container cavity, store reaction liquid, and in described reaction powder accommodation cavity, store and can meet and react rear and produce the reaction solid that gas expands elastic bag with this reaction liquid.
A kind of Hemostasis of above-mentioned stomach first aid capsule haemostat, it comprises the steps: that (1) stomach first aid capsule haemostat enters after stomach, gastric solubility gelatin band dissolves under the effect of gastric juice, and reaction liquid container cavity, reaction powder accommodation cavity and free elastic expansion chamber are interconnected; (2) reaction liquid and reaction solid meet, luminescence-producing reaction and generate gas make elastic bag expand; (3) along with the generation gradually of gas, this elastic bag volume increases and is fitted on coat of the stomach, tackles mutually coat of the stomach and puts on certain oppressive force, and in the time that this oppressive force is greater than the intravascular pressure of coat of the stomach bleeding part, stopped bleeding, realizes the object that stomach stops blooding.
As a modification of the present invention, described reaction liquid is H
2o liquid.Described reaction solid is CaC
2powder.
The present invention adopts CaC
2with water H
2o reaction, the equation of reaction is as follows:
CaC
2?+?2H
2O?→?Ca(OH)
2?+?C
2H
2
CaC
2?+?H
2O?→?CaO+C
2H
2
W-response speed can reach molecular balance in several minutes, and reaction generates the C that is slightly soluble in water
2h
2gas, obtains strutting the gas of elastic bag.
Calculated example: with the gastric capacity 1.5L that is grown up, be basic assumption condition on an empty stomach, need in the elastic bag of 1.5L, produce 1.5 atmospheric pressure, suppose in elastic bag other conditions situation that is near the mark, the number of moles of gas amount (actual state is because the number of moles of gas that the reasons such as human body temperature is higher, exothermic heat of reaction need will be less) needing.
N=1.5*1.5/22.4≈0.1Mol
Corresponding CaC
2quality
M
sOLID=molal weight (CaC
2) * molal quantity N ≈ 6.4g
Required CaC
2volume
V
solid=M/ρ=6.4/2.22≤3cm
3
The quality of required water
M
liquid=molal weight (H
2o) * molal quantity N ≈ 1.8g
V
liquid=M/ρ=2*1.8/1≤3.6cm
3
As mentioned above, the volume of the required reaction solid holding of elastic bag and reaction liquid is no more than 7 cm
3.
Beneficial effect of the present invention is: the structural design of stomach first aid capsule haemostat provided by the invention is ingenious, reasonable, adopt chemical reaction technology the combination balloon tamponade physics mode that gas occurs to stop blooding, determined curative effect, patient can use in the very first time, with rapid Bleeding control symptom, for successive treatment wins the quality time, and omnidistance without medical worker's participation, and patient oneself can save oneself; Clinical normal use Sengstaken-Blakemore tube is as hemostasis measure at present, but because glossopharyngeum reaction seriously can not tolerate, there is the risk of suffocating in part patient, stomach first aid capsule haemostat of the present invention only need be as oral capsule medicine simultaneously, without any discomfort reaction, easy to use, quick; Hemostasis provided by the invention is easy to realize, convenient and swift, be easy to implement, definite effect, patient can be for subsequent use with oneself, once there are a large amount of hematemesis, swallowable capsule hemostasis immediately, for patient wins the quality time.
Brief description of the drawings
Fig. 1 is embodiments of the invention 1 structural representations.
Fig. 2 is embodiments of the invention 2 structural representations.
Fig. 3 is embodiments of the invention 3 structural representations.
Fig. 4 is embodiments of the invention 4 structural representations.
Detailed description of the invention
Embodiment 1: referring to Fig. 1, a kind of stomach first aid capsule haemostat that the embodiment of the present invention provides, it comprises elastic bag, on described elastic bag, tie up gastric solubility gelatin band 1, make the inner chamber of this elastic bag form reaction liquid container cavity 3, reaction powder accommodation cavity 2 and a free elastic expansion chamber 4 with separate space, wherein said reaction liquid container cavity 3 and the adjacent setting of reaction powder accommodation cavity 2, described free elastic expansion chamber 4 is positioned at a side of described reaction liquid container cavity 3.In described reaction liquid container cavity 3, store reaction liquid, and in described reaction powder accommodation cavity 2, store and can meet and react rear and produce the reaction solid that gas expands elastic bag with this reaction liquid.Gastric solubility gelatin band 1 can adopt gastric solubility gelatin to make.In other embodiment, this gastric solubility gelatin band 1 also can adopt gastric solubility coating material to make, and adopts gastric solubility acrylic resin to make.
A kind of Hemostasis of above-mentioned stomach first aid capsule haemostat, it comprises the steps: that (1) stomach first aid capsule haemostat enters after stomach, gastric solubility gelatin band 1 dissolves under the effect of gastric juice, and reaction liquid container cavity 3, reaction powder accommodation cavity 2 and free elastic expansion chamber 4 are interconnected; (2) reaction liquid and reaction solid meet, luminescence-producing reaction and generate gas make elastic bag expand; (3) along with the generation gradually of gas, this elastic bag volume increases and is fitted on coat of the stomach, tackles mutually coat of the stomach and puts on certain oppressive force, and in the time that this oppressive force is greater than the intravascular pressure of coat of the stomach bleeding part, stopped bleeding, realizes the object that stomach stops blooding.
In the present embodiment, described reaction liquid is preferably H
2o liquid, described reaction solid is preferably CaC
2powder.W-response speed can reach molecular balance in several minutes, and reaction generates the C that is slightly soluble in water
2h
2gas, obtains strutting the gas of elastic bag, and this gas is after use, and immediately having occurred to leak also can not produce obvious toxic-side effects to human body, is the gas that belongs to comparatively safe; The side-product Ca (OH) that reaction produces
2, CaO is alkalescence, even if elastic bag breaks, a small amount of gastric juice that is dissolved in, also can not produce obvious toxic-side effects for human body.
In other embodiment, reaction liquid and reaction solid also can adopt other both can meet react and produce gas and elastic bag is expanded and the reactant that produces can not produce other type reaction liquid of obvious toxic and side effects and react solid human body.If reaction liquid is water, and reaction solid can be aluminium sulfide, aluminium carbonate, hydrotalcite, ferric carbonate etc.This reactant, except generating gas, also generates aluminium hydroxide, though be alkalescence, alkalescence is not very strong, and wherein hydrotalcite, also for gastric ulcer and duodenal ulcer, can not produce obvious toxic and side effects to human body.
Embodiment 2: referring to Fig. 2, a kind of stomach first aid capsule haemostat and Hemostasis thereof that the embodiment of the present invention provides, it is substantially the same manner as Example 1, distinctive points in, described reaction liquid container cavity 3 and the adjacent setting of reaction powder accommodation cavity 2, a side that is positioned at described reaction powder accommodation cavity 2 in described free elastic expansion chamber 4.
Embodiment 3: referring to Fig. 3, a kind of stomach first aid capsule haemostat and Hemostasis thereof that the embodiment of the present invention provides, it is substantially the same manner as Example 1, and distinctive points is arranged in order setting in, described reaction liquid container cavity 3, free elastic expansion chamber 4 and reaction powder accommodation cavity 2.
Embodiment 4: referring to Fig. 4, a kind of stomach first aid capsule haemostat and Hemostasis thereof that the embodiment of the present invention provides, it is substantially the same manner as Example 1, distinctive points in, described reaction liquid container cavity 3 and the adjacent setting of reaction powder accommodation cavity 2, the quantity in described free elastic expansion chamber 4 is two, is separately positioned on a side of reaction liquid container cavity 3 corresponding thereto or reaction powder accommodation cavity 2.Be provided with a free elastic expansion chamber 4 and be provided with equally a free elastic expansion chamber 4 in a side of reaction liquid container cavity 3 in a side of described reaction powder accommodation cavity 2.To meet the hemostasis demand of different crowd stomach size.
The present invention adopts chemical reaction technology the combination balloon tamponade physics mode that gas occurs to stop blooding, determined curative effect.Large in some amounts of bleeding, shock patient uses hemostasis capsule to stop blooding rapidly, and simultaneously actively blood transfusion and infusion is gone further scope or operative treatment after patient's vital signs stable again.The patient who causes the underlying diseases of digestive tract hemorrhage for existence can be for subsequent use with oneself, once there are a large amount of hematemesis, swallowable capsule hemostasis immediately, for patient wins the quality time.Treat stable disease, when scope or operative treatment are made adequate preparation, under scope or Direct Surgery venting, and take out stomach first aid capsule haemostat.
The present invention specifically has following advantage.
1) quick: patient can use rapid Bleeding control symptom in the very first time, particularly patient large in some amounts of bleeding, shock uses stomach first aid capsule haemostat of the present invention can realize the object of hemostasis rapidly, actively coordinate blood transfusion and infusion simultaneously, after patient's vital signs stable, go again further scope or operative treatment, for successive treatment wins the quality time.
2) convenient: omnidistance without medical worker's participation, patient can oneself save oneself.The patient who causes the underlying diseases of digestive tract hemorrhage for existence can be for subsequent use with oneself, once there are a large amount of hematemesis, swallowable capsule hemostasis immediately.
3) current clinical normal use Sengstaken-Blakemore tube is as hemostasis measure, although also can realize the object of hemostasis, but part patient seriously can not tolerate because glossopharyngeum reacts, there is the risk of suffocating simultaneously, stomach first aid capsule haemostat of the present invention only need be as oral capsule medicine, without any discomfort reaction, easy to use.
The announcement of book and instruction according to the above description, those skilled in the art in the invention can also change and revise above-mentioned embodiment.Therefore, the present invention is not limited to detailed description of the invention disclosed and described above, also should fall in the protection domain of claim of the present invention modifications and changes more of the present invention.In addition,, although used some specific terms in this description, these terms just for convenience of description, do not form any restriction to the present invention.As described in the above embodiment the present invention, adopt structure same or analogous with it and other haemostat of obtaining and its Hemostasis, all in protection domain of the present invention.
Claims (7)
1. a stomach first aid capsule haemostat, it comprises elastic bag, it is characterized in that, on described elastic bag, tie up gastric solubility gelatin band, make the inner chamber of this elastic bag form reaction liquid container cavity, reaction powder accommodation cavity and at least one free elastic expansion chamber with separate space, in described reaction liquid container cavity, store reaction liquid, and in described reaction powder accommodation cavity, store and can meet and react rear and produce the reaction solid that gas expands elastic bag with this reaction liquid.
2. stomach first aid capsule haemostat according to claim 1, it is characterized in that, described reaction liquid container cavity and the adjacent setting of reaction powder accommodation cavity, the quantity in described free elastic expansion chamber is one, it is positioned at a side of described reaction liquid container cavity or reaction powder accommodation cavity.
3. stomach first aid capsule haemostat according to claim 1, it is characterized in that, described reaction liquid container cavity and the adjacent setting of reaction powder accommodation cavity, the quantity in described free elastic expansion chamber is two, is separately positioned on a side of reaction liquid container cavity corresponding thereto or reaction powder accommodation cavity.
4. stomach first aid capsule haemostat according to claim 2, is characterized in that, the quantity in described free elastic expansion chamber is one, and described reaction liquid container cavity, free elastic expansion chamber and reaction powder accommodation cavity are arranged in order setting.
5. according to the stomach first aid capsule haemostat one of claim 1 to 4 Suo Shu, it is characterized in that, described reaction liquid is H
2o liquid.
6. stomach first aid capsule haemostat according to claim 5, is characterized in that, described reaction solid is CaC
2powder.
7. a Hemostasis for the described stomach first aid of one of claim 1-6 capsule haemostat, is characterized in that, it comprises the steps:
(1) stomach first aid capsule haemostat enters after stomach, and gastric solubility gelatin band dissolves under the effect of gastric juice, and reaction liquid container cavity, reaction powder accommodation cavity and free elastic expansion chamber are interconnected;
(2) reaction liquid and reaction solid meet, luminescence-producing reaction and generate gas make elastic bag expand;
(3) along with the generation gradually of gas, this elastic bag volume increases and is fitted on coat of the stomach, tackles mutually coat of the stomach and puts on certain oppressive force, and in the time that this oppressive force is greater than the intravascular pressure of coat of the stomach bleeding part, stopped bleeding, realizes the object that stomach stops blooding.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410194775.7A CN104000628B (en) | 2014-05-10 | 2014-05-10 | Stomach first aid capsule haemostat and Hemostasis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410194775.7A CN104000628B (en) | 2014-05-10 | 2014-05-10 | Stomach first aid capsule haemostat and Hemostasis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104000628A true CN104000628A (en) | 2014-08-27 |
| CN104000628B CN104000628B (en) | 2018-05-22 |
Family
ID=51361732
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410194775.7A Active CN104000628B (en) | 2014-05-10 | 2014-05-10 | Stomach first aid capsule haemostat and Hemostasis |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109513048A (en) * | 2018-10-09 | 2019-03-26 | 沛嘉医疗科技(苏州)有限公司 | A kind of cross-linking method of bioartificial tissue |
| CN116602807A (en) * | 2023-05-22 | 2023-08-18 | 张勤生 | Capsule type self-produced gas stomach volume-reducing weight-reducing air bag |
| CN116603067A (en) * | 2023-05-22 | 2023-08-18 | 张勤生 | Temperature-induced gradient self-gas-generating composition and application thereof |
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2014
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109513048A (en) * | 2018-10-09 | 2019-03-26 | 沛嘉医疗科技(苏州)有限公司 | A kind of cross-linking method of bioartificial tissue |
| CN116602807A (en) * | 2023-05-22 | 2023-08-18 | 张勤生 | Capsule type self-produced gas stomach volume-reducing weight-reducing air bag |
| CN116603067A (en) * | 2023-05-22 | 2023-08-18 | 张勤生 | Temperature-induced gradient self-gas-generating composition and application thereof |
| CN116603067B (en) * | 2023-05-22 | 2024-04-12 | 张勤生 | Temperature-induced gradient self-gas-generating composition and application thereof |
| CN116602807B (en) * | 2023-05-22 | 2024-05-28 | 张勤生 | Capsule type self-produced gas stomach volume-reducing weight-reducing air bag |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104000628B (en) | 2018-05-22 |
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