CN103980137A - Post-treatment method of L-glutamic acid fermentation liquid - Google Patents
Post-treatment method of L-glutamic acid fermentation liquid Download PDFInfo
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- CN103980137A CN103980137A CN201410240929.1A CN201410240929A CN103980137A CN 103980137 A CN103980137 A CN 103980137A CN 201410240929 A CN201410240929 A CN 201410240929A CN 103980137 A CN103980137 A CN 103980137A
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- pidolidone
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- fermented liquid
- glutamic acid
- sorbent material
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Abstract
The invention discloses a post-treatment method of L-glutamic acid fermentation liquid. The post-treatment method comprises the following steps: removing bacteria, proteins and fermentation metabolites from the fermentation liquid, as a raw material, of L-glutamic acid produced by adopting a fermentation process under the adsorption effect of an adsorbent; filtering through a multi-channel pipe type metal membrane; processing filtrate obtained by removing impurities by adopting an isoelectric point evaporation and crystallization process to obtain a target product, namely L-glutamic acid. Through detection, the purity of L-glutamic acid prepared by adopting the method is more than 99.5%. According to the method, a coal ash magnetized fertilizer is used as the adsorbent for adsorbing the impurities; the coal ash magnetized fertilizer after impurity adsorption can serve as manure to be used for crops and meets the environment-friendly requirements. The method is mild in condition, good in impurity removal effect, simple and convenient to operate, low in cost and suitable for industrialized production.
Description
Technical field
The present invention relates to a kind of post-treating method of Pidolidone fermented liquid.
Background technology
The production of China's monosodium glutamate (Pidolidone sodium) is the fermentative routes adopting taking grain as raw material substantially, after having fermented, in fermented liquid except containing primary product Pidolidone, also contain thalline, soluble proteins, residual sugar, pigment and other fermentation by-products, the impurity such as these thalline, albumen had both affected the important factor of Pidolidone extraction yield and quality, caused again a difficult problem for waste water environmental protection treatment.
In prior art, the method for extracting Pidolidone from Pidolidone fermented liquid mainly contains direct iso-electric point consecutive evaporation decrease temperature crystalline, through membrane filtration recrystallize, ion exchange method etc.Low with method difficult treatment and the yield of direct crystallization; When the direct membrane filtration of fermented liquid, speed is very slow, and filter membrane is easy to the blocked regeneration difficulty that makes; Ion exchange method resin demand is large, and aftertreatment is loaded down with trivial details; Meanwhile, the impurity such as thalline, albumen in fermented liquid brings very large pressure with conventional treatment method to environment protection.
Chinese patent CN201832453U discloses the continuous isoelectric point crystallizing precipitation apparatus of a kind of Pidolidone, is a kind of improvement greatly to direct iso-electric point evaporative crystallization, but is difficult to solve the problem of waste water.
Chinese patent CN103224454A discloses a kind of separation-extraction technology of Pidolidone, it adopts Strong acid ion-exchanger to extract the Pidolidone in iso-electric point liquid, although the bronsted lowry acids and bases bronsted lowry that this technique is a large amount of compared with traditional technology saving, the problem that is difficult to fundamentally solve wastewater treatment.
Summary of the invention
Problem to be solved by this invention is to provide a kind of post-treating method of Pidolidone fermented liquid, extracts the deficiency of complex operation, wastewater treatment difficulty in Pidolidone process to overcome prior art fermentation method.
Technical conceive of the present invention is such:
Taking the fermented liquid of fermentative Production Pidolidone as raw material, adsorb thalline, albumen, the fermentating metabolism product removed in fermented liquid by sorbent material, through hyperchannel tubular type metal membrane filter, the filtrate that removal of impurities obtains adopts the method for iso-electric point consecutive evaporation, crystallization, obtains target product Pidolidone.
For realizing above-mentioned design, the present invention mainly adopts following technical scheme:
A kind of post-treating method of Pidolidone fermented liquid, comprise the steps: to add sorbent material in industrial Pidolidone fermented liquid, under room temperature, stir 2-4 hour, remove sorbent material through vacuum filtration, the filtrate obtaining is filtered through hyperchannel tubular type metallic membrane, and the filtrate of gained obtains target product Pidolidone through the method for iso-electric point consecutive evaporation, decrease temperature crystalline.
Further, described sorbent material is magnetized fly-ash fertilizer.
Again, the preparation method of described hyperchannel tubular type metallic membrane is: taking Porous Stainless Steel as supporter, at described Porous Stainless Steel internal surface sintering one deck Ti
2o film, is described hyperchannel tubular type metallic membrane, and the aperture of described hyperchannel tubular type metallic membrane is 0.1-0.2 μ m.
Separately, the mass volume ratio of described sorbent material and industrial Pidolidone fermented liquid is 1:10-50, g/ml.
The high purity Pidolidone obtaining by the inventive method after testing gained Pidolidone purity is greater than 99.5%;
The present invention's beneficial effect compared with prior art:
1) the present invention adopts the method for conventional iso-electric point consecutive evaporation, decrease temperature crystalline can avoid the loss of direct crystallization method product in prior art, and while avoiding direct membrane filtration, speed is slow, film easily stops up, the problems such as difficulty of regenerating;
2) the present invention is adsorbed taking magnetized fly-ash fertilizer as sorbent material, and the magnetized fly-ash fertilizer after absorption impurity can be used as fertilizer for farm crop, meets the requirement of environmental protection;
3) method mild condition of the present invention, good impurity removing effect, easy and simple to handle, with low cost, be suitable for suitability for industrialized production.
Embodiment
Below by specific embodiment, the present invention is described further, but embodiment does not limit the scope of the invention.
Embodiment 1
Get 5000mL industry Pidolidone fermented liquid, add 200g magnetized fly-ash fertilizer as sorbent material, under room temperature, stir 2 hours, magnetized fly-ash fertilizer is removed in vacuum filtration, the filtrate obtaining is that 0.1 μ m hyperchannel tubular type metallic membrane filters with aperture, the filtrate of gained, by conventional iso-electric point consecutive evaporation, decrease temperature crystalline, obtains high purity Pidolidone.Gained Pidolidone purity is greater than 99.5% after testing.
Embodiment 2
Get 2000mL industry Pidolidone fermented liquid, add 200g magnetized fly-ash fertilizer as sorbent material, under room temperature, stir 4 hours, magnetized fly-ash fertilizer is removed in vacuum filtration, the filtrate obtaining is that 0.2 μ m hyperchannel tubular type metallic membrane filters with aperture, the filtrate of gained, by conventional iso-electric point consecutive evaporation, decrease temperature crystalline, obtains high purity Pidolidone.Gained Pidolidone purity is greater than 99.5% after testing.
It should be noted that, above embodiment is only unrestricted in order to technical scheme of the present invention to be described.Although the present invention is had been described in detail with reference to preferred embodiment, those of ordinary skill in the art is to be understood that, can modify or be equal to replacement the technical scheme of invention, and not depart from the scope of technical solution of the present invention, it all should be encompassed in claim scope of the present invention.
Claims (4)
1. the post-treating method of a Pidolidone fermented liquid, it is characterized in that, comprise the steps: to add sorbent material in industrial Pidolidone fermented liquid, under room temperature, stir 2-4 hour, remove sorbent material through vacuum filtration, the filtrate obtaining is filtered through hyperchannel tubular type metallic membrane, and the filtrate of gained obtains target product Pidolidone through the method for iso-electric point consecutive evaporation, decrease temperature crystalline.
2. the post-treating method of Pidolidone fermented liquid according to claim 1, is characterized in that, described sorbent material is magnetized fly-ash fertilizer.
3. the post-treating method of Pidolidone fermented liquid according to claim 1, is characterized in that, the preparation method of described hyperchannel tubular type metallic membrane is: taking Porous Stainless Steel as supporter, at described Porous Stainless Steel internal surface sintering one deck Ti
2o film, is described hyperchannel tubular type metallic membrane, and the aperture of described hyperchannel tubular type metallic membrane is 0.1-0.2 μ m.
4. the post-treating method of Pidolidone fermented liquid according to claim 1, is characterized in that, the mass volume ratio of described sorbent material and described industrial Pidolidone fermented liquid is 1:10-50, g/ml.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410240929.1A CN103980137B (en) | 2014-05-30 | 2014-05-30 | A kind of post-processing approach of L glutami acid fermentation liquors |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201410240929.1A CN103980137B (en) | 2014-05-30 | 2014-05-30 | A kind of post-processing approach of L glutami acid fermentation liquors |
Publications (2)
| Publication Number | Publication Date |
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| CN103980137A true CN103980137A (en) | 2014-08-13 |
| CN103980137B CN103980137B (en) | 2017-07-11 |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1531866A (en) * | 2003-03-20 | 2004-09-29 | 凯能高科技工程〔上海〕有限公司 | Method for producing monosodium glutamate |
| CN101293718A (en) * | 2008-06-16 | 2008-10-29 | 湖北富邦化工科技有限公司 | Immediate processing method for sewage water |
| CN101391928A (en) * | 2008-11-12 | 2009-03-25 | 秦皇岛领先科技发展有限公司 | Fertilizer composition and use thereof |
| CN101402584A (en) * | 2008-11-07 | 2009-04-08 | 天津科技大学 | Method for separating and extracting L-glutamic acid from fermentation liquor |
-
2014
- 2014-05-30 CN CN201410240929.1A patent/CN103980137B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1531866A (en) * | 2003-03-20 | 2004-09-29 | 凯能高科技工程〔上海〕有限公司 | Method for producing monosodium glutamate |
| CN101293718A (en) * | 2008-06-16 | 2008-10-29 | 湖北富邦化工科技有限公司 | Immediate processing method for sewage water |
| CN101402584A (en) * | 2008-11-07 | 2009-04-08 | 天津科技大学 | Method for separating and extracting L-glutamic acid from fermentation liquor |
| CN101391928A (en) * | 2008-11-12 | 2009-03-25 | 秦皇岛领先科技发展有限公司 | Fertilizer composition and use thereof |
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| CN103980137B (en) | 2017-07-11 |
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