CN103977494A - Method for estimating pressure control ventilation air leakage based on flow waveform - Google Patents
Method for estimating pressure control ventilation air leakage based on flow waveform Download PDFInfo
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- CN103977494A CN103977494A CN201410233829.6A CN201410233829A CN103977494A CN 103977494 A CN103977494 A CN 103977494A CN 201410233829 A CN201410233829 A CN 201410233829A CN 103977494 A CN103977494 A CN 103977494A
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Abstract
The invention belongs to a method for estimating pressure control ventilation air leakage of a respirator, and specifically relates to a method for estimating the pressure control ventilation air leakage based on a flow waveform and a peak value thereof and based on the integral capacity waveform of the flow waveform and the peak value of the integral capacity waveform. The method comprises the steps of acquiring an air supply flow signal at the air supply end of the respirator in the process of noninvasive ventilation in a pressure control mode, thereby obtaining a ventilation flow waveform and a flow peak value, carrying out integration to obtain a capacity waveform and a capacity peak value, comparing an acquired flow waveform curve and a capacity waveform curve obtained by calculating the integral of the acquired flow waveform curve with flow and capacity waveform standard curves, respectively, thereby determining an air leakage grade, and then estimating the air leakage in a respiration period by use of the extracted flow and capacity peak values based on a flow peak value-air leakage relation and a capacity peak value-air leakage relation.
Description
Technical field
The invention belongs to a kind of evaluation method of respirator pressure controlled ventilation air leakage, be specifically related to a kind of based on flow waveform and peak value thereof, and integration capacity waveform and peak value thereof based on flow waveform, the method for carrying out the estimation of pressure controlled ventilation air leakage.
Background technology
Noinvasive ventilation does not need to set up wound artificial airway, has the advantages such as ventilation mortality rate is low, patient tolerability is good, has been widely used in the patient of clinical treatment breathing function deficiency and has been applied to family therapy sleep apnea syndrome.But, research finds that patient is accepting in noinvasive venting process to produce some untoward reaction, as gas leakage, skin irritation, rhinitis, abdominal distention, headband discomfort etc., wherein leak gas because of its universal existence, uncontrollability and larger hazardness, that the ventilation of application noinvasive needs the subject matter solving, need to detect and estimate air leakage gas leakage, and then air leakage is carried out to fine compensation.The present invention is directed to the pressure controlled ventilation pattern that noinvasive is ventilated conventional, a kind of method based on flow waveform estimation air leakage is proposed, concrete grammar is in pressure control mode noinvasive venting process, gather gas supply flow signal at respirator air feed end, obtain ventilation flow rate waveform and peak flow, obtain capacity waveform and capacity peak value by integration, the capacity wavy curve that the flow waveform curve that utilization collects and integration obtain respectively with flow, thereby capacity waveform standard curve is compared and is determined gas leakage grade, be related to based on peak flow-gas leakage relation and capacity peak value-gas leakage the flow that utilization is extracted, air leakage in the capacity peak value breathing cycle of estimation.
Summary of the invention
The present invention proposes a kind of evaluation method of respirator pressure controlled ventilation air leakage, be specifically related to a kind of based on flow waveform and peak value thereof, and integration capacity waveform and peak value thereof based on flow waveform, the method for carrying out the estimation of pressure controlled ventilation air leakage.
Its step comprises, when respirator carries out noinvasive ventilation with pressure control mode to patient, gather gas circuit flow signal at respirator air feed end, obtain flow waveform and peak flow, obtain capacity waveform and capacity peak value by the integration of calculated flow rate signal, thereby by comparing and determine gas leakage grade with flow, capacity waveform standard curve, based on peak flow-gas leakage be related to utilization extract peak flow estimate the air leakage in this breathing cycle, based on capacity peak value-gas leakage be related to utilization extract capacity peak value estimate the air leakage in this breathing cycle.
Further, the collection of gas circuit flow signal as above is on the pipeline being connected with patient at respirator, to be arranged near the flow signal that flow transducer is set respirator suction end and gathers gas circuit;
Further, flow waveform as above and peak flow by the feature of collection flow signal, flow waveform curve can be described by 2 characteristic points, comprising the plateau value of peak flow and air-breathing section;
Further, capacity waveform as above is that the integration by calculating the flow signal that gathers obtains, and capacity wavy curve can be described by 2 characteristic points, comprising capacity peak value and air-breathing section of ascending curve tangent slope;
Further, above-mentioned flow, capacity waveform standard curve comprise under pressure controlled ventilation condition without gas leakage, a small amount of gas leakage (gas leakage is below 10%), middle amount gas leakage (gas leakage 10-35%), a large amount of gas leakage (gas leakage is greater than 35%) 4 kinds of corresponding flows of gas leakage degree, capacity wave characteristics;
Further, the estimation of air leakage is to carry out linear operation and obtain by gas circuit peak flow being brought into peak flow-air leakage relation function, or carries out linear operation and obtain by gas circuit capacity peak value being brought into capacity peak value-air leakage relation function;
Further, above-mentioned peak flow-air leakage relation function has been described the linear relationship of gas circuit peak flow and this breathing cycle air leakage under pressure controlled ventilation, and its form is: V
leak=K ﹒ F
max+ B, wherein V
leakbe approximate air leakage in the breathing cycle, F
maxfor gas circuit peak flow, K and B are that parameter is based on gas leakage test experience platform, on the basis of great amount of samples experiment, obtain;
Further, above-mentioned capacity peak value-air leakage relation function has been described the linear relationship of pressure controlled ventilation therapeutic method to keep the adverse QI flowing downwards appearance of a street amount peak value and this breathing cycle air leakage, and its form is: V
leak=K ﹒ V
tmax+ B, wherein V
leakbe approximate air leakage in the breathing cycle, V
tmaxfor gas circuit capacity peak value, K and B are that parameter is based on gas leakage test experience platform, on the basis of great amount of samples experiment, obtain;
Further, air leakage estimation as above is to carry out linear operation by gas circuit peak flow being brought into peak flow-air leakage relation function, or carry out linear operation by gas circuit capacity peak value being brought into capacity peak value-air leakage relation function, obtain approximate air leakage in this breathing cycle.
Brief description of the drawings
Fig. 1 method implementing procedure figure
Gas circuit flow (a), capacity (b) wave character point labelling in the breathing cycle of Fig. 2
Fig. 3 flow (a, b, c, d), capacity (e, f, g, h) waveform standard curve
Fig. 4 peak flow-air leakage relation function curve (a), capacity peak value-air leakage relation function curve (b)
Detailed description of the invention
Below in conjunction with accompanying drawing and specific embodiment, the present invention is described in further detail.
The key step that is illustrated in figure 1 a kind of method based on flow waveform estimated pressure control ventilation air leakage, specifically comprises:
(1) for the ventilation of respirator pressure control noinvasive, place gas flow sensor at respirator air feed end, with venting process Real-time Collection gas circuit flow signal;
(2) according to collected gas circuit flow signal, form the flow waveform curve of breathing cycle one by one, as shown in (a) in Fig. 2, and gas circuit flow signal is extracted to wavy curve characteristic point, the A point, the B point that are marked as (a) in Fig. 2, wherein A point is the peak point of gas circuit flow, and B point is the plateau of air-breathing period;
(3) integration of the calculating gas circuit flow signal that collects, obtain capacity wavy curve, as shown in (b) in Fig. 2, and gas circuit capacity signal is extracted to wavy curve characteristic point, the A point and the k that are marked as (b) in Fig. 2, wherein A point is the peak point of gas circuit capacity, and k is air-breathing section of ascending curve tangent slope;
(4) the gas circuit flow waveform curve obtaining and flow waveform standard curve are compared and then estimated gas leakage degree, as shown in (a-d) in Fig. 3, A point increases to some extent when a small amount of gas leakage (gas leakage is less than 10%), start to occur B point, increase gradually when gas leakage degree continues to increase value corresponding to B point while reaching medium (10%< air leakage <35%) and a large amount of (air leakage >35%) level;
(5) the gas circuit capacity wavy curve obtaining and capacity waveform standard curve are compared and then estimated gas leakage degree, as shown in (e-h) in Fig. 3, A point and k value increase to some extent when a small amount of gas leakage (gas leakage is less than 10%), increase gradually when gas leakage degree continues to increase k value while reaching medium (10%< air leakage <35%) and a large amount of (air leakage >35%) level;
(6) can be brought in peak flow-air leakage relation function and calculate the approximation of trying to achieve air leakage according to gas circuit peak flow, wherein peak flow-air leakage relation function is first-order linear function V
leak=42F
max-1895, its curve is as shown in (a) in Fig. 4;
(7) can be brought in capacity peak value-air leakage relation function and calculate the approximation of trying to achieve air leakage according to gas circuit capacity peak value, wherein capacity peak value-air leakage relation function is first-order linear function V
leak=V
leak=V
tmax-235, its curve is as shown in (b) in Fig. 4;
Method based on flow waveform estimated pressure control ventilation air leakage is based on gas circuit flow detection, realizes with reference to serial flow, capacity waveform standard curve and flow, capacity peak value-air leakage relation function.Wherein utilize detection flow, capacity wavy curve and flow, capacity waveform standard curve to compare the gas leakage degree that only can obtain being similar to, and utilize gas circuit flow, capacity peak value and air leakage relation function can obtain quantitative air leakage.
Claims (8)
1. the method based on flow waveform estimated pressure control ventilation air leakage, is characterized in that, carries out the ventilation air leakage estimation under noinvasive aeration condition with pressure control mode, and concrete steps comprise:
When respirator (01) carries out noinvasive ventilation with pressure control mode to patient (02), place flow transducer (03) at respirator air feed end and carry out the detection of gas circuit flow;
To the flow signal in gas circuit, obtain real-time flow waveform signal (04) by flow transducer (03) Real-time Collection, obtain flow waveform feature, comprise peak flow, flow waveform is the plateau value of air-breathing section;
By flow signal is carried out to integration, calculate capacity signal waveform (10), obtain capacity waveform characteristic, comprise capacity peak value, capacity waveform is at the slope of air-breathing section of rising.
For air flue flow, capacity signal in the breathing cycle, obtain flow, capacity curve waveform, compare with reference to flow waveform standard curve (06) and capacity waveform standard curve (12) respectively, realize the estimation of gas leakage degree (07);
Utilize the peak flow (05) extracting, and according to based on peak flow-air leakage approximation relation function (08), estimate, obtain the approximate air leakage (09) of each breathing cycle in pressure controlled ventilation process.
Utilize the capacity peak value (11) extracting, and according to based on capacity peak value-air leakage approximation relation function (13), estimate, obtain the approximate air leakage (09) of each breathing cycle in pressure controlled ventilation process.
2. as claimed in claim 1; A kind of method based on flow waveform estimated pressure control ventilation air leakage has been utilized gas circuit flow waveform information (04), it is characterized in that: in pressure controlled ventilation process at air feed end Real-time Collection gas circuit flow signal, extract the characteristic point of flow waveform (04), comprise the plateau value (B) of peak flow point (A) and air-breathing section.
3. as claimed in claim 1; A kind of method based on flow waveform estimated pressure control ventilation air leakage has been utilized gas circuit flow waveform information (04), it is characterized in that: calculate its integration and can obtain gas circuit capacity waveshape signal (10), the characteristic point of extraction capacity waveform (10), comprises capacity peak point (A) and air-breathing section of ascending curve tangent slope k.
4. as claimed in claim 1, a kind of method based on flow waveform estimated pressure control ventilation air leakage has been utilized the leak gas estimation of degree of pressure controlled ventilation down-off waveform standard curve (06) and capacity waveform standard curve (12), it is characterized in that: flow waveform standard curve (06) and capacity waveform standard curve (12) comprise under pressure controlled ventilation condition without gas leakage, a small amount of gas leakage (gas leakage is below 10%), middle amount gas leakage (gas leakage 10-35%), a large amount of gas leakage (gas leakage is greater than 35%) 4 kinds of corresponding flows of gas leakage degree, capacity wave characteristics.
5. as claimed in claim 1, method based on flow waveform estimated pressure control ventilation air leakage has utilized peak flow-air leakage relation function (08) to carry out an estimation for air leakage (09) in the breathing cycle, it is characterized in that: air leakage (09) is to carry out linear operation and obtain by gas circuit peak flow being brought into peak flow-air leakage relation function.
6. as claimed in claim 1, method based on flow waveform estimated pressure control ventilation air leakage has utilized capacity peak value-air leakage relation function (13) to carry out an estimation for air leakage (09) in the breathing cycle, it is characterized in that: air leakage (09) is to carry out linear operation and obtain by gas circuit capacity peak value being brought into capacity peak value-air leakage relation function.
7. as described in right 1, a kind of method based on flow waveform estimated pressure control ventilation air leakage has been utilized peak flow-air leakage relation function (08), it is characterized in that: peak flow-air leakage relation function (08) has been described the linear relationship of gas circuit peak flow and this breathing cycle air leakage under pressure controlled ventilation, and its form is: V
leak=K ﹒ F
max+ B, wherein V
leakbe approximate air leakage in the breathing cycle, F
maxfor gas circuit peak flow, K and B are that parameter is based on gas leakage test experience platform, on the basis of great amount of samples experiment, obtain.
8. as described in right 1, a kind of method based on flow waveform estimated pressure control ventilation air leakage has been utilized capacity peak value-air leakage relation function (13), it is characterized in that: capacity peak value-air leakage relation function (13) has been described the linear relationship of pressure controlled ventilation therapeutic method to keep the adverse QI flowing downwards appearance of a street amount peak value and this breathing cycle air leakage, and its form is: V
leak=K ﹒ V
tmax+ B, wherein V
leakbe approximate air leakage in the breathing cycle, V
tmaxfor gas circuit capacity peak value, K and B are that parameter is based on gas leakage test experience platform, on the basis of great amount of samples experiment, obtain.
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| CN201410233829.6A CN103977494B (en) | 2014-05-29 | 2014-05-29 | A kind of method controlling ventilation air leakage based on flow waveform estimated pressure |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105381526A (en) * | 2015-12-08 | 2016-03-09 | 杭州电子科技大学 | Intelligent outflow resistance switching simulation breathing apparatus |
| CN108287043A (en) * | 2017-12-29 | 2018-07-17 | 湖南明康中锦医疗科技发展有限公司 | Lung ventilator gas leakage quantity measuring method, device, storage medium and computer equipment |
| CN108619604A (en) * | 2017-03-21 | 2018-10-09 | 小牛科技河北有限公司 | A kind of control method that atomization quantity can be made to change with the variation of respiratory flow |
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| CN103180002A (en) * | 2010-07-30 | 2013-06-26 | 雷斯梅德有限公司 | Methods and devices with leak detection |
| CN103357095A (en) * | 2006-08-30 | 2013-10-23 | 雷斯梅德有限公司 | Determination of leak during CPAP treatment |
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Patent Citations (5)
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| CN103357095A (en) * | 2006-08-30 | 2013-10-23 | 雷斯梅德有限公司 | Determination of leak during CPAP treatment |
| CN103180002A (en) * | 2010-07-30 | 2013-06-26 | 雷斯梅德有限公司 | Methods and devices with leak detection |
| CN102641536A (en) * | 2011-02-17 | 2012-08-22 | 新利虹科技股份有限公司 | Positive pressure breathing device and air leakage quantity obtaining method of positive pressure breathing device |
| WO2013054217A1 (en) * | 2011-09-13 | 2013-04-18 | Koninklijke Philips Electronics N.V. | Pressure based gas leak testing |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105381526A (en) * | 2015-12-08 | 2016-03-09 | 杭州电子科技大学 | Intelligent outflow resistance switching simulation breathing apparatus |
| CN108619604A (en) * | 2017-03-21 | 2018-10-09 | 小牛科技河北有限公司 | A kind of control method that atomization quantity can be made to change with the variation of respiratory flow |
| CN108287043A (en) * | 2017-12-29 | 2018-07-17 | 湖南明康中锦医疗科技发展有限公司 | Lung ventilator gas leakage quantity measuring method, device, storage medium and computer equipment |
| CN108287043B (en) * | 2017-12-29 | 2020-03-10 | 湖南明康中锦医疗科技发展有限公司 | Breathing machine air leakage detection method and device, storage medium and computer equipment |
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