CN103933754A - Automatic solid phase extraction equipment - Google Patents
Automatic solid phase extraction equipment Download PDFInfo
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- CN103933754A CN103933754A CN201410129635.1A CN201410129635A CN103933754A CN 103933754 A CN103933754 A CN 103933754A CN 201410129635 A CN201410129635 A CN 201410129635A CN 103933754 A CN103933754 A CN 103933754A
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Abstract
The invention belongs to the field of extraction equipment for pretreatment of samples, and discloses automatic solid phase extraction equipment. The automatic solid phase extraction equipment comprises a stand, a sample injection device, a sample turntable, an extraction column turntable, a liquid feeding device, a pressure device, an extraction liquid turntable and a control device, wherein the sample turntable, the extraction column turntable and the extraction liquid turntable are successively mounted on the stand from high to low in a horizontal rotation manner; multiple extraction column support holes are formed in the circumference of the outer edge of the extraction column turntable; multiple sample support holes and one liquid injection through holes are formed in the circumference of the outer edge of the sample turntable; multiple extraction liquid pipe support holes are formed in the circumference of the outer edge of the extraction liquid turntable; the sample injection device is used for extracting samples from a sample tube and injecting samples into the solid phase extraction column through a liquid injection through hole; the pressure device is used for feeding solvent into the solid phase extraction column; the control device is used for controlling operation of the whole extraction equipment. By adopting the equipment, the difficulty of labor operation can be lowered, and the testing effect can be improved.
Description
Technical field
The present invention relates to the extraction equipment field to sample pretreatment, particularly relate to a kind of SPE equipment automatically.
Background technology
Diesel oil is complicated hydrocarbon mixture, and carbon number is about 10-22.Wherein, the content of saturated hydrocarbons and aromatic hydrocarbons is an important indicator weighing diesel oil characteristic.In order to detect the content of saturated hydrocarbons and aromatic hydrocarbons in diesel oil, after generally saturated hydrocarbons being separated from diesel oil with aromatic hydrocarbons, detect.
Existing measuring method is generally to adopt the method for SPE that the saturated hydrocarbons in diesel oil and aromatic hydrocarbons are carried out to extract and separate, in saturated hydrocarbon solution after extract and separate and aromatic hydrocarbons solution, add internal standard compound, and use instrument to carry out gas chromatographic analysis, to obtain the content data of saturated hydrocarbons and aromatic hydrocarbons.Existing laboratory facilities generally adopt manual operation extraction, and artificial extraction comprises the following steps: (1) adds 0.5mL pentane (n-hexane) in solid-phase extraction column; (2) be fixed mutually after absorption completely until pentane, draw about 0.lmL sample with 0.25mL syringe and splash on the sieve plate in solid-phase extraction column; (3) use successively 2mL (2.5ml) pentane (n-hexane) and 0.5mL dichloromethane rinse to fix phase, extract the wherein saturated hydrocarbons of absorption, under solid-phase extraction column, receive and rush saturated hydrocarbons washing lotion with 25mL conical flask, treat that carrene has just entered fixing phase time completely, solid-phase extraction column is transferred in another 25mL conical flask, use again 2mL (2.5mL) dichloromethane rinse to fix phase, extract adsorbed aromatic hydrocarbons; (4) in reception has the 25mL conical flask of flushing liquor of saturated hydrocarbons and aromatic hydrocarbons, accurately add 1.00mL inner mark solution respectively with pipette, shake up; (5) finally will use respectively instrument to carry out gas chromatographic analysis containing interior target saturated hydrocarbons and aromatic hydrocarbons solution.
The method of operating of prior art has following shortcoming:
(1) use manual operation to carry out liquid feeding, the low precision of liquid feeding, test effect is poor;
(2) in extraction process, reagent used is volatile, for having relatively high expectations of operating personnel;
(3) in experiment, test the diesel oil of one batch, need to get multiple samples, repeatedly repeat, operating personnel's labour intensity is large, and the poor stability manually repeating, and further reduces test effect.
Summary of the invention
(1) technical problem that will solve
The object of this invention is to provide a kind of manual operation difficulty that reduces, reduce operation sequence, improve the automatic SPE equipment of test effect.
(2) technical scheme
In order to solve the problems of the technologies described above, the invention provides a kind of SPE equipment automatically, comprising: frame, sampling device, sample rotating disk, extraction column rotating disk, liquid-adding device, pressue device and extract rotating disk;
Described sample rotating disk, extraction column rotating disk and extract rotating disk are successively from high to low and can horizontally rotate and be arranged in described frame; The circumference of described extraction column rotating disk outer is provided with multiple extraction column prop holes, for support solid-phase extraction column; The circumference of described sample rotating disk outer is provided with multiple sample prop holes and a fluid injection through hole, and described sample prop hole is for support coupon; The circumference of described extract rotating disk outer is provided with multiple liquid extraction pipe prop holes, for support liquid extraction pipe;
The outer of described sample rotating disk and described extraction column rotating disk partially overlaps, and described extraction column prop hole is positioned at the below of described fluid injection through hole; The outer of described extraction column rotating disk and described extract rotating disk partially overlaps, and described extraction column prop hole is positioned at the top of described liquid extraction pipe prop hole; Described sampling device is fixedly mounted on the top of described sample rotating disk and described extraction column rotating disk intersection, for extracting sample from described coupon, and injects sample by described fluid injection through hole to described solid-phase extraction column; Described pressue device is arranged on the top of described extraction column rotating disk and described extract rotating disk intersection, for injecting compressed gas to described solid-phase extraction column; Described liquid-adding device is arranged in described frame, for adding solvent to described solid-phase extraction column.
Wherein, described liquid-adding device comprises liquid feeding mechanism and travel mechanism, and described liquid feeding mechanism comprises fluid supplier and liquid feeding head, and described liquid feeding head is fixed in described travel mechanism; Described fluid supplier is communicated with described liquid feeding head by pipeline; Described travel mechanism is arranged on the side top of described extraction column pallet, for described liquid feeding head being moved to the top of described solid-phase extraction column.
Wherein, described travel mechanism is wobble component, and described wobble component comprises swinging mounting, bracing wire, swinging guide rails, swing slide block, swing arm, return springs and wobble drive source, and described swinging mounting is fixed in described frame; Described swinging guide rails is fixed on described swinging mounting; Described swing slide block is slidably mounted in described swinging guide rails; The stage casing of described swing arm is hingedly mounted on described swinging mounting, and described swing arm is divided into driving section and wobble segment; Described driving section is hinged with described swing slide block; Described liquid feeding head is arranged on the end of described wobble segment; Described return springs is connected between described wobble segment and described swinging mounting; Described swing slide block is connected with wobble drive source by described bracing wire.
Wherein, described pressue device comprises pressurizer and elevating mechanism, and described pressurizer comprises source of the gas and inflating valve, and described inflating valve is arranged on elevating mechanism, and is positioned at described solid-phase extraction column top; Described source of the gas is connected with described inflating valve by pipeline; Described elevating mechanism drives described inflating valve lifting moving.
Wherein, described elevating mechanism comprises: lifting drive source, lifting arm, lifting slider and riser guide, and described riser guide is vertically fixed in described frame; Described lifting slider is slidably mounted on described riser guide; Described lifting arm is fixed on described lifting slider; Described inflating valve is arranged on described lifting arm; Described lifting arm is connected with described lifting drive source.
Wherein, described lifting drive source is linear cylinder, being arranged in described frame of described linear cylinder; The axis of the piston of described linear cylinder is connected with described lifting arm.
Wherein, described lifting drive source comprises: spindle motor and leading screw, and described spindle motor is fixedly mounted in described frame; The screw mandrel of described leading screw is connected with described spindle motor, and the nut of described leading screw and described lifting arm fix.
Wherein, described swing slide block is connected with described lifting arm by described bracing wire.
Wherein, described sampling device comprises: sampling installing plate, syringe, sampling guide rail, elevating bracket, ram seat, sampling motor, stepper motor, synchronizing wheel and Timing Belt, and described sampling installing plate is vertically fixed in described frame; Described sampling guide rails assembling is on described sampling installing plate; Described elevating bracket and ram seat are slidably mounted in respectively on described sampling guide rail; The syringe of described syringe is fixed on described elevating bracket, and the push rod of described syringe is fixed in described ram seat; Described stepper motor is arranged on described elevating bracket; Described synchronizing wheel is arranged on the motor shaft of described stepper motor; Described Timing Belt is arranged in described ram seat; Described synchronizing wheel is meshed with Timing Belt; Described sampling motor is arranged on described sampling installing plate, and by elevating bracket described in belt drives.
Wherein, this automatic SPE equipment also comprises drawer, and described drawer comprises drawer body and drawer sliding rail, and described extraction column rotating disk and extract rotating disk are fixed on described drawer body; Described drawer sliding rail is arranged in described frame; Described drawer body is slidably mounted on described drawer sliding rail.
Wherein, this automatic SPE equipment also comprises drawer-lock, and described drawer-lock is arranged in described frame, for drawer described in locking.
Wherein, described drawer-lock comprises lock bolt, snap, guide pin bushing and push rod, and described guide pin bushing is arranged in described frame; Described lock bolt is slidably mounted in described guide pin bushing; The front end of described lock bolt snaps in described drawer body, and described snap is arranged on the rear end of described lock bolt; Described push rod is located in described frame slidably; The front end of described push rod is provided with push rod lozenges, and described lock bolt is provided with the boss of unblanking, and described push rod and described lock bolt are perpendicular, described push rod lozenges with described in the boss of unblanking corresponding.
Wherein, described drawer-lock also comprises button and back-moving spring, and described button is fixed on the rear end of described push rod, and described back-moving spring is sleeved on described push rod, and the described frame of pressure and described button are pushed up respectively in the two ends of described back-moving spring.
Wherein, this SPE equipment also comprises control device, and described control device is connected with described sampling device, sample rotating disk, extraction column rotating disk, liquid-adding device, pressue device and extract rotating disk respectively.
(3) beneficial effect
Automatic SPE equipment provided by the invention can disposablely complete the mask work of many group samples, and the disposable mask work that completes multiple samples reduces labour intensity, improves separating rate.This equipment does not need artificial liquid feeding, reduces contacting of artificial and chemical substance, raising working environment.Use the sampling of control device Quality control, liquid feeding etc., liquid feeding precision is high, and measured data are accurate.
Brief description of the drawings
Fig. 1 is the overall perspective view of embodiments of the invention 1;
Fig. 2 is the front view of the sampling device of embodiments of the invention 1;
Fig. 3 is the right view of the sampling device of embodiments of the invention 1;
Fig. 4 is the front view of the part-structure of sample rotating disk, extraction column rotating disk, the extract rotating disk of embodiments of the invention 1;
Fig. 5 is the top view of the part-structure of sample rotating disk, extraction column rotating disk, the extract rotating disk of embodiments of the invention 1;
Fig. 6 is the top view of the part-structure of liquid-adding device, the pressue device of embodiments of the invention 1;
Fig. 7 is the front view of the part-structure of liquid-adding device, the pressue device of embodiments of the invention 1;
Fig. 8 is the enlarged drawing of A part in Fig. 7;
Fig. 9 is the drawer of the embodiment of the present invention 5 and the top view of drawer-lock (duty);
Figure 10 is the drawer of the embodiment of the present invention 5 and the top view of drawer-lock (off working state).
In figure, 1: sampling device; 2: sample rotating disk; 3: extraction column rotating disk; 4: extract rotating disk; 5: pressue device; 6: liquid-adding device; 7: swinging mounting; 8: coupon; 9: solid-phase extraction column; 10: frame; 11: liquid extraction pipe; 101: sample introduction installing plate; 102: elevating bracket; 103: syringe; 104: stepper motor; 105: synchronizing wheel; 106: ram seat; 107: Timing Belt; 108: sampling motor; 109: sampling guide rail; 201: probe tube prop hole; 202: fluid injection through hole; 203: sewer pipe prop hole; 204: cleaning fluid conduit saddle hole; 301: extraction column prop hole; 401: liquid extraction pipe prop hole; 501: source of the gas; 502: inflating valve; 503: lifting arm; 504: lifting slider; 505: leading screw; 506: riser guide; 507: spindle motor; 601: fluid supplier; 602: swinging guide rails; 603: swing slide block; 604: bracing wire; 605: swing arm; 606: return springs; 607: gantry pillars; 608: liquid feeding head; 20: housing; 30: drawer; 31: drawer body; 32: drawer sliding rail; 40: drawer-lock; 41: lock bolt; 42: snap; 43: push rod; 44: back-moving spring; 45: button; 46: guide pin bushing.
Detailed description of the invention
Below in conjunction with drawings and Examples, the specific embodiment of the present invention is described in further detail.Following instance is used for illustrating the present invention, but is not used for limiting the scope of the invention.
Embodiment 1
As shown in Fig. 1 to 8, automatic SPE equipment of the present invention, comprising: frame 10, sampling device 1, sample rotating disk 2, extraction column rotating disk 3, liquid-adding device 6, pressue device 5, extract rotating disk 4 and control device (scheming not shown).
Frame 10 selects alloy material to be welded.Sample rotating disk 2, extraction column rotating disk 3 and extract rotating disk 4 spread configuration from high to low successively, and respectively by being arranged in frame 10 on swinging mounting 7, sample rotating disk 2, extraction column rotating disk 3 and extract rotating disk 4 all can be horizontally rotated.The circumference of extraction column rotating disk 3 outers is provided with multiple extraction column prop holes 301, for support solid-phase extraction column 9, solid-phase extraction column 9 is prior art, is placed in extraction column prop hole 301, the upper edge of solid-phase extraction column 9 is placed on extraction column rotating disk 3, and lower through-hole stretches out extraction column rotating disk 3.The circumference of sample rotating disk 2 outers is provided with multiple sample prop holes 201 and a fluid injection through hole 202, and sample prop hole 201 is for support coupon 8.On sample rotating disk 2, be also provided with sewer pipe prop hole 203 and cleaning fluid conduit saddle hole 204, sewer pipe prop hole 203 is for support sewer pipe, and cleaning fluid conduit saddle hole 204 is for support cleaning fluid pipe.The circumference of extract rotating disk 4 outers is provided with multiple extraction conduit saddles 401, for support liquid extraction pipe 11.Coupon 8 and liquid extraction pipe 11 are the test tube of port with radial flange, and the material of test tube is not limit.
Sample rotating disk 2 partially overlaps with the outer of extraction column rotating disk 3, and intersection extraction column prop hole 301 be positioned at fluid injection through hole 202 below; Extraction column rotating disk 3 partially overlaps with the outer of extract rotating disk 4, and intersection extraction column prop hole 301 be positioned at liquid extraction pipe prop hole 401 above.Sampling device 1 is fixedly mounted on the top of sample rotating disk 2 and extraction column rotating disk 3 intersection, extracts sample, and inject sample by fluid injection through hole 202 to solid-phase extraction column 9 for the coupon 8 from being placed on sample prop hole 201; Pressue device 5 is arranged on the top of extraction column rotating disk 3 and extract rotating disk 4 intersection, for injecting compressed gas to solid-phase extraction column 9; Liquid-adding device 6 is arranged in frame, for adding solvent to the solid-phase extraction column 9 being placed in extraction column prop hole 301.
Control device is connected with sampling device 1, sample rotating disk 2, extraction column rotating disk 3, liquid-adding device 6, pressue device 5 and extract rotating disk 4 respectively, for controlling the work of sampling device 1, sample rotating disk 2, extraction column rotating disk 3, liquid-adding device 6, pressue device 5 and extract rotating disk 4.Control device comprises interconnective guidance panel and main frame, stores multiple control programs in main frame, and multiple control programs comprise the separation control method that is applicable to plurality of liquid, and each separation control method includes the separation control instruction of multiple sets of numbers.Main frame is connected with sampling device 1, sample rotating disk 2, extraction column rotating disk 3, liquid-adding device 6, pressue device 5 and extract rotating disk 4 respectively, user of service selects corresponding control instruction by guidance panel, main frame sending controling instruction is to unit such as sampling device 1, sample rotating disk 2, extraction column rotating disk 3, liquid-adding device 6, pressue device 5 and extract rotating disks 4, make unit carry out work according to control instruction, separate with solid phase thereby realize sample introduction.
In the present embodiment, liquid-adding device 6 comprises liquid feeding mechanism and travel mechanism, and liquid feeding mechanism comprises fluid supplier 601 and liquid feeding head 608, and liquid feeding head 608 is fixedly mounted in travel mechanism; Fluid supplier 601 is communicated with liquid feeding head 608 by pipeline.Fluid supplier 601 comprises multiple fluid reservoirs and is located at respectively the liquid meter unit of the fluid reservoir port of export, the liquid measure of getting that liquid meter unit is set according to control program measures the liquid in fluid reservoir, and be transported to liquid feeding head 608 by pipeline, inject solid-phase extraction column 9 from liquid feeding head 608.Travel mechanism is arranged on the side top of extraction column pallet 3, for liquid feeding head 608 being moved to the top of solid-phase extraction column 9.In the present embodiment, travel mechanism is included as wobble component, and wobble component comprises swinging mounting 607, bracing wire 604, swinging guide rails 602, swings slide block 603, swing arm 605 and return springs 606, and swinging mounting 607 is fixed in frame 10; Swinging guide rails 602 is fixed on swinging mounting 607; Swinging slide block 603 is slidably mounted in swinging guide rails 602.The middle part of swing arm 605 is hingedly mounted on swinging mounting 607, and swing arm is divided into driving section and wobble segment along hinged position.Drive section and swing slide block 603 to be hinged; Preferably, driving section to be provided with chute, swinging slide block 603 and be provided with a sliding axle matching with chute, swinging slide block 603 and be hinged by sliding axle and chute with driving section; Or driving section to be provided with sliding axle, on swing slide block 603, a chute matching with sliding axle is being set, swinging slide block 603 and drive section by being hinged sliding axle and coordinating of chute.Liquid feeding head 608 is arranged on the end of wobble segment; Return springs 606 is connected between wobble segment and swinging mounting 607, or return springs 606 is connected between swing component and frame 10.Preferably return springs 606 is extension spring.Swinging slide block 603 is connected with wobble drive source by bracing wire 604.Preferably, be provided with multiple through holes in swing arm 605 inside, multiple through holes are communicated with liquid feeding head 608 respectively, and fluid supplier 601 is connected with through hole by pipeline, solvent in fluid supplier 601 flows through pipeline successively, through hole flows to liquid feeding head 608, is filled in solid-phase extraction column 9 by liquid feeding head.
In the present embodiment, pressue device 5 comprises pressurizer and elevating mechanism, and pressurizer comprises source of the gas 501 and inflating valve 502, and source of the gas 501 is selected high-pressure pump, and compressed gas is provided; Inflating valve 502 is arranged on elevating mechanism, and is positioned at solid-phase extraction column 9 tops; Source of the gas 501 is connected with inflating valve 502 by pipeline; Elevating mechanism drives inflating valve 502 to be connected or separation with solid-phase extraction column 9.Elevating mechanism comprises: lifting drive source, lifting arm 503, lifting slider 504 and riser guide 506, and riser guide 506 is vertically fixed in frame 10; Lifting slider 504 is slidably mounted on riser guide 506; Lifting arm 503 is fixed on lifting slider 504; Inflating valve 502 is arranged on lifting arm 503; Lifting arm 503 is connected with lifting drive source, and lifting drive source drives lifting arm to move up and down along riser guide, and inflating valve 502 moves up and down, and is connected or separation with the solid-phase extraction column 9 being placed on extraction column rotating disk 3.Lifting drive source comprises spindle motor 507 and leading screw 505, spindle motor 507 is fixedly mounted in frame, the screw mandrel of leading screw 505 is connected with spindle motor 507, and vertically install, the nut of leading screw 505 and lifting arm 503 fix, when spindle motor 507 moves, screw mandrel rotates, and the lifting arm 503 being connected with nut moves along screw mandrel.Preferably, lifting drive source, simultaneously as wobble drive source, swings slide block 603 and is connected with lifting arm 503 by bracing wire 604.The one end that is bracing wire 604 is connected with swing slide block 603, and the other end is connected with lifting arm 503; Or one end of bracing wire 604 is connected with swing slide block 603, and the other end is connected with the nut of leading screw.In the time that spindle motor 507 drives lifting arm 503 to rise, lifting arm 503 pulls bracing wire, and the swing arm 605 of swing mechanism is swung, and liquid feeding head 608 is swung to the top of solid-phase extraction column 9, and solution is injected solid-phase extraction column by fluid supplier 601.In the time that spindle motor 507 drives lifting arm 503 to decline, swing arm 605 resets under the effect of return springs, and inflating valve 502 declines and is connected with solid-phase extraction column 9, and source of the gas 601 feeds compressed gas to solid-phase extraction column 9.
In the present embodiment, when lifting arm 503 rises, inflating valve 502 rises, wobble component swings to liquid feeding head 608 lower position of inflating valve 502, in the time that lifting arm 503 declines, inflating valve 502 moves down, and the swing arm of wobble component resets, liquid feeding head 608 shifts out, and inflating valve 502 is connected with solid-phase extraction column phase 9.Liquid-adding device and pressue device form a link gear, the mechanism of not only having simplified equipment, and can avoid liquid feeding head and inflating valve mutually to interfere, Accident prevention occurs.Link gear can make inflating valve be connected with solid-phase extraction column rapidly, prevents solvent evaporates.
Further, in the present embodiment, sampling device comprises sampling installing plate 101, syringe 103, sampling guide rail 109, elevating bracket 102, ram seat 106, sampling motor 108, stepper motor 104, synchronizing wheel 105 and Timing Belt 107, and sampling installing plate 101 is vertically fixed in frame 10; Sampling guide rail 109 is arranged on sampling installing plate 101.Elevating bracket 102 and ram seat 106 are slidably mounted on sampling guide rail 109 by slide block respectively; Syringe 103 comprises syringe, push rod and syringe needle, and the syringe of syringe 103 is fixed on elevating bracket 102, and the push rod of syringe 103 is fixed in ram seat 106.Stepper motor 104 is also fixedly mounted on elevating bracket 102; Synchronizing wheel 105 is arranged on the motor shaft of stepper motor 104; Timing Belt 107 is arranged in ram seat 106; Synchronizing wheel 105 is meshed with Timing Belt 107; Sampling motor 108 is arranged on sampling installing plate 101, and by the lifting moving of belt drives elevating bracket 10.Sampling installing plate 101 arranges a sampling rotating shaft, and sampling rotating shaft parallels with sampling motor 108, and belt bridges between sampling motor 108 and sampling rotating shaft, and elevating bracket 102 is connected with belt, moves with belt simultaneously.
When work, diesel oil sample is contained in coupon 8, is placed in coupon prop hole 201, in the extraction column prop hole 301 of extraction column rotating disk 3, place solid-phase extraction column 9, in the liquid extraction pipe prop hole 401 of extract rotating disk 4, place liquid extraction pipe 11, then start automatic SPE equipment.
Sampling:
(1) sample rotating disk 2 rotates, and makes coupon 8 be positioned at the below of sampling device 1; Sampling device 1 starts, and elevating bracket 103 moves down, and the syringe needle of syringe 103 stretches in coupon 8, and ram seat 106 moves up, and syringe 103 extracts sample; Elevating bracket 102 moves up and drives syringe 103 upwards to shift out coupon 8.(2) sample rotating disk 2 rotates, until the position of fluid injection through hole 202 is positioned at the below of sampling device 1; Extraction column 3 dial rotation, make extraction column prop hole 301 be positioned at the below of fluid injection through hole 202; Lifting motor 108 drives elevating bracket 102 to move down, and the syringe needle of syringe 103 is stretched in fluid injection through hole 202, and ram seat 106 moves down, and the sample in syringe 103 is injected in solid-phase extraction column 9 according to set amount.Repeat above-mentioned steps, make to be all injected in the solid-phase extraction column on extraction column pallet sample.
Extraction:
(1) rotate extraction column pallet 3, make solid-phase extraction column 9 be positioned at the below of the inflating valve 502 of pressue device 5.(2) spindle motor 507 drives lifting arm 503 to move up, lifting arm 503 drives swing arm 605 to swing by bracing wire 604, make to be arranged on the top that liquid feeding head 608 in swing arm 605 swings to solid-phase extraction column 9, start fluid supplier 601 and add solvent in solid-phase extraction column 9; Extract rotating disk 4 rotates, the below that liquid extraction pipe 11 is forwarded be positioned to the extraction column prop hole 301 of inflating valve below, spindle motor 507 drives lifting arm 503 to decline, under the effect of return springs 606, swing arm 605 resets, liquid feeding head 608 swings to be removed, and inflating valve 502 moves down, and is connected with solid-phase extraction column 9, source of the gas 501 provides compressed gas to inflating valve 502, saturated hydrocarbons in SPE extraction separates, then repeating step (2), completes the separation of aromatic hydrocarbons.Repeatedly repeating step (1) and (2), complete the mask work of batch of multiple samples.
Embodiment 2
The present embodiment is substantially the same manner as Example 1, and institute's difference is, the travel mechanism of liquid-adding device also can be not limited to wobble component, can be for liquid feeding head being moved to arbitrarily to the mechanism of solid-phase extraction column top position.
Embodiment 3
The present embodiment is substantially the same manner as Example 1, and institute's difference is, the liquid-adding device of the present embodiment comprises fluid supplier, liquid feeding head and detent mechanism, and fluid supplier is connected with liquid feeding head by pipeline, and liquid feeding head is arranged on the top of extraction column prop hole by detent mechanism.When work, extraction column dial rotation, turns to liquid feeding head below by solid-phase extraction column, fluid supplier injects solvent by liquid feeding head in solid-phase extraction column, continues solid-phase extraction column to inflating valve below, and inflating valve moves down, source of the gas injects compressed gas in solid-phase extraction column, completes extraction.
Embodiment 4
The present embodiment is substantially the same manner as Example 1, and institute's difference is, the lifting drive source of the present embodiment is linear cylinder, being arranged in frame of linear cylinder; The axis of the piston of linear cylinder is connected with lifting arm.Linear cylinder can be cylinder or hydraulic cylinder, and cylinder or hydraulic cylinder can be chosen as required, do not repeat them here.
Embodiment 5
The present embodiment and embodiment 1 to 4 are basic identical, institute's difference is, as shown in Figures 9 and 10, the automatic SPE equipment of the present embodiment also comprises drawer 30, drawer comprises drawer body 31 and drawer sliding rail 32, and extraction column rotating disk 3 and extract rotating disk 4 are fixed on drawer body 31; Drawer sliding rail 32 is arranged in frame 10; Drawer body 31 is slidably mounted on drawer sliding rail 32.Preferably drawer sliding rail 32 is two, and two drawer sliding rails 32 be arranged in parallel, and drawer body 31 is slidably mounted on drawer sliding rail 32 by slide block, adopts two drawer sliding rails 32, and drawer body 31 is extracted out with the stability pushing better.As shown in Figure 9, under the state advancing at drawer body 31, extraction column rotating disk 3 and extract rotating disk 4 are positioned at the lower position of liquid-adding device, and automatically SPE equipment is in can duty; As shown in figure 10, under the state that drawer body 31 is extracted out, equipment, in inoperative shape, is convenient to user and places and fetch solid-phase extraction column 9 and liquid extraction pipe 11 to extraction column rotating disk 3 and extract rotating disk 4.Simultaneously, further in frame 10 surroundings, housing 20 is set, by the inner space of extraction equipment and space outerpace isolation, the pollutant such as dust on the equipment that prevents falls in the time not using, extracts extraction column rotating disk 3 and extract rotating disk 4 out housing 20 outsides by drawer and places and fetch solid-phase extraction column 9 and liquid extraction pipe 11.
Further, when under drawer body 31 advanced state, in order to ensure that drawer body 31 is not moved in the equipment course of work, guarantee the normal extraction of equipment, automatic SPE equipment of the present invention also comprises drawer-lock 40, and drawer-lock 40 is arranged in frame 10, for locking drawer 30.Drawer-lock 40 comprises lock bolt 41, snap 42, guide pin bushing 46, push rod 43, button 45 and back-moving spring 44, and guide pin bushing 46 is arranged in frame 10; Lock bolt 41 is slidably mounted in guide pin bushing 46; The front end of lock bolt 41 snaps in drawer body 31, and snap 42 is arranged on the rear end of lock bolt 41; Push rod 43 is located in frame 10 slidably; The front end of push rod 43 is provided with push rod lozenges, and lock bolt 41 is provided with the boss of unblanking, and push rod 43 is perpendicular with lock bolt 41, and push rod lozenges is corresponding with the boss of unblanking.Button 45 is fixed on the rear end of push rod 43, and back-moving spring 44 is sleeved on push rod 43, and the two ends of back-moving spring 44 top pressure rack 10 and button 15 respectively.In the time that needs are extracted drawer body 31 out, press button 45, push rod 43 is promoted forward, push rod lozenges and the boss relative sliding of unblanking, the rear end compression snap 42 of lock bolt 41, the fore-end that snaps in drawer body 31 is extracted out, and drawer body 31 slides and extracts out along drawer sliding rail 32, decontrol after button, back-moving spring 44 resets push rod 43.Avoid in the process of extraction equipment work, inoperative personnel extract drawer to have an accident out.
Use automatic SPE equipment of the present invention can disposablely complete the mask work of many group samples, the disposable mask work that completes multiple samples, reduces operating personnel's labour intensity, improves separating rate.This equipment does not need artificial liquid feeding, reduces manually and the contacting of chemical substance, and improves operating personnel's working environment, ensures to greatest extent operating personnel's safety.Use the sampling of control device Quality control, liquid feeding etc., sampling and liquid feeding taken amount precision are high, and measured data are more accurate.The error of repeatedly measuring is less, improves repeatability, the stability repeatedly measured, improves the accuracy of data.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (14)
1. an automatic SPE equipment, is characterized in that, comprising: frame, sampling device, sample rotating disk, extraction column rotating disk, liquid-adding device, pressue device and extract rotating disk;
Described sample rotating disk, extraction column rotating disk and extract rotating disk are successively from high to low and can horizontally rotate and be arranged in described frame; The circumference of described extraction column rotating disk outer is provided with multiple extraction column prop holes, for support solid-phase extraction column; The circumference of described sample rotating disk outer is provided with multiple sample prop holes and a fluid injection through hole, and described sample prop hole is for support coupon; The circumference of described extract rotating disk outer is provided with multiple liquid extraction pipe prop holes, for support liquid extraction pipe;
The outer of described sample rotating disk and described extraction column rotating disk partially overlaps, and described extraction column prop hole is positioned at the below of described fluid injection through hole; The outer of described extraction column rotating disk and described extract rotating disk partially overlaps, and described extraction column prop hole is positioned at the top of described liquid extraction pipe prop hole; Described sampling device is fixedly mounted on the top of described sample rotating disk and described extraction column rotating disk intersection, for extracting sample from described coupon, and injects sample by described fluid injection through hole to described solid-phase extraction column; Described pressue device is arranged on the top of described extraction column rotating disk and described extract rotating disk intersection, for injecting compressed gas to described solid-phase extraction column; Described liquid-adding device is arranged in described frame, for adding solvent to described solid-phase extraction column.
2. automatic SPE equipment as claimed in claim 1, is characterized in that, described liquid-adding device comprises liquid feeding mechanism and travel mechanism, and described liquid feeding mechanism comprises fluid supplier and liquid feeding head, and described liquid feeding head is fixed in described travel mechanism; Described fluid supplier is communicated with described liquid feeding head by pipeline; Described travel mechanism is arranged on the side top of described extraction column pallet, for described liquid feeding head being moved to the top of described solid-phase extraction column.
3. automatic SPE equipment as claimed in claim 2, it is characterized in that, described travel mechanism is wobble component, described wobble component comprises swinging mounting, bracing wire, swinging guide rails, swing slide block, swing arm, return springs and wobble drive source, and described swinging mounting is fixed in described frame; Described swinging guide rails is fixed on described swinging mounting; Described swing slide block is slidably mounted in described swinging guide rails; The stage casing of described swing arm is hingedly mounted on described swinging mounting, and described swing arm is divided into driving section and wobble segment; Described driving section is hinged with described swing slide block; Described liquid feeding head is arranged on the end of described wobble segment; Described return springs is connected between described wobble segment and described swinging mounting; Described swing slide block is connected with wobble drive source by described bracing wire.
4. automatic SPE equipment as claimed in claim 3, it is characterized in that, described pressue device comprises pressurizer and elevating mechanism, and described pressurizer comprises source of the gas and inflating valve, described inflating valve is arranged on elevating mechanism, and is positioned at described solid-phase extraction column top; Described source of the gas is connected with described inflating valve by pipeline; Described elevating mechanism drives described inflating valve lifting moving.
5. automatic SPE equipment as claimed in claim 4, is characterized in that, described elevating mechanism comprises: lifting drive source, lifting arm, lifting slider and riser guide, and described riser guide is vertically fixed in described frame; Described lifting slider is slidably mounted on described riser guide; Described lifting arm is fixed on described lifting slider; Described inflating valve is arranged on described lifting arm; Described lifting arm is connected with described lifting drive source.
6. automatic SPE equipment as claimed in claim 5, is characterized in that, described lifting drive source is linear cylinder, being arranged in described frame of described linear cylinder; The axis of the piston of described linear cylinder is connected with described lifting arm.
7. automatic SPE equipment as claimed in claim 5, is characterized in that, described lifting drive source comprises: spindle motor and leading screw, and described spindle motor is fixedly mounted in described frame; The screw mandrel of described leading screw is connected with described spindle motor, and the nut of described leading screw and described lifting arm fix.
8. automatic SPE equipment as claimed in claim 7, is characterized in that, described swing slide block is connected with described lifting arm by described bracing wire.
9. automatic SPE equipment as claimed in claim 1, it is characterized in that, described sampling device comprises: sampling installing plate, syringe, sampling guide rail, elevating bracket, ram seat, sampling motor, stepper motor, synchronizing wheel and Timing Belt, and described sampling installing plate is vertically fixed in described frame; Described sampling guide rails assembling is on described sampling installing plate; Described elevating bracket and ram seat are slidably mounted in respectively on described sampling guide rail; The syringe of described syringe is fixed on described elevating bracket, and the push rod of described syringe is fixed in described ram seat; Described stepper motor is arranged on described elevating bracket; Described synchronizing wheel is arranged on the motor shaft of described stepper motor; Described Timing Belt is arranged in described ram seat; Described synchronizing wheel is meshed with Timing Belt; Described sampling motor is arranged on described sampling installing plate, and by elevating bracket described in belt drives.
10. automatic SPE equipment as claimed in claim 1, is characterized in that, this automatic SPE equipment also comprises drawer, and described drawer comprises drawer body and drawer sliding rail, and described extraction column rotating disk and extract rotating disk are fixed on described drawer body; Described drawer sliding rail is arranged in described frame; Described drawer body is slidably mounted on described drawer sliding rail.
11. automatic SPE equipment as claimed in claim 10, is characterized in that, this automatic SPE equipment also comprises drawer-lock, and described drawer-lock is arranged in described frame, for drawer described in locking.
12. automatic SPE equipment as claimed in claim 11, is characterized in that, described drawer-lock comprises lock bolt, snap, guide pin bushing and push rod, and described guide pin bushing is arranged in described frame; Described lock bolt is slidably mounted in described guide pin bushing; The front end of described lock bolt snaps in described drawer body, and described snap is arranged on the rear end of described lock bolt; Described push rod is located in described frame slidably; The front end of described push rod is provided with push rod lozenges, and described lock bolt is provided with the boss of unblanking, and described push rod and described lock bolt are perpendicular, described push rod lozenges with described in the boss of unblanking corresponding.
13. automatic SPE equipment as claimed in claim 12, it is characterized in that, described drawer-lock also comprises button and back-moving spring, described button is fixed on the rear end of described push rod, described back-moving spring is sleeved on described push rod, and the described frame of pressure and described button are pushed up respectively in the two ends of described back-moving spring.
14. automatic SPE equipment as described in claim 1 to 13 any one, it is characterized in that, this SPE equipment also comprises control device, and described control device is connected with described sampling device, sample rotating disk, extraction column rotating disk, liquid-adding device, pressue device and extract rotating disk respectively.
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| CN201410129635.1A CN103933754B (en) | 2014-04-01 | 2014-04-01 | Automatic SPE equipment |
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| CN201410129635.1A CN103933754B (en) | 2014-04-01 | 2014-04-01 | Automatic SPE equipment |
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| CN106248869A (en) * | 2016-04-28 | 2016-12-21 | 深圳出入境检验检疫局食品检验检疫技术中心 | A kind of liquid infusion shock machine being applied to dispersive liquid-liquid microextraction |
| CN106441975A (en) * | 2016-08-31 | 2017-02-22 | 苏州兴亚净化工程有限公司 | Clean sampling trolley convenient for taking and placing |
| CN106872612A (en) * | 2015-12-11 | 2017-06-20 | 中国科学院大连化学物理研究所 | A kind of Full automatic array solid-phase extraction device |
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| CN106872612A (en) * | 2015-12-11 | 2017-06-20 | 中国科学院大连化学物理研究所 | A kind of Full automatic array solid-phase extraction device |
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| CN112774240A (en) * | 2021-01-19 | 2021-05-11 | 胡艳皇 | Bioengineering is with circulated extraction equipment |
| CN112946133A (en) * | 2021-02-04 | 2021-06-11 | 科诺美(北京)科技有限公司 | Application method of biological sample pretreatment system |
| CN113238009A (en) * | 2021-05-13 | 2021-08-10 | 新疆农垦科学院 | A solid-phase extraction device for food detects |
| CN113552279A (en) * | 2021-07-21 | 2021-10-26 | 常州民生环境检测有限公司 | Quick sample preparation equipment for ion chromatographic analysis test |
| CN113552279B (en) * | 2021-07-21 | 2024-02-06 | 常州民生环境检测有限公司 | Quick sample preparation equipment for ion chromatographic analysis test |
| CN114264618A (en) * | 2021-11-15 | 2022-04-01 | 中国烟草总公司福建省公司 | Method for detecting starch content in tobacco |
| CN114878730A (en) * | 2022-06-16 | 2022-08-09 | 陕西科技大学 | Goat milk adulteration detection device and method integrating solid phase microextraction and in-situ mass spectrometry |
| CN114878730B (en) * | 2022-06-16 | 2023-08-15 | 陕西科技大学 | Sheep milk adulteration detection device and method integrating solid-phase microextraction and in-situ mass spectrum |
| CN115327009A (en) * | 2022-07-27 | 2022-11-11 | 广东电网有限责任公司广州供电局 | Oil and gas injection mechanism and oil and gas injection method |
| CN115327009B (en) * | 2022-07-27 | 2024-03-22 | 广东电网有限责任公司广州供电局 | Oiling and gas injection mechanism and oiling and gas injection method |
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