CN103903666B - A kind of method that X-ray machine outgoing spectrum is carried out bandpass filtering - Google Patents

A kind of method that X-ray machine outgoing spectrum is carried out bandpass filtering Download PDF

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Publication number
CN103903666B
CN103903666B CN201410148270.7A CN201410148270A CN103903666B CN 103903666 B CN103903666 B CN 103903666B CN 201410148270 A CN201410148270 A CN 201410148270A CN 103903666 B CN103903666 B CN 103903666B
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ray
ray machine
outgoing spectrum
liquor kalii
spectrum
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CN103903666A (en
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吴自玉
王圣浩
韩华杰
张灿
杨蒙
王志立
高昆
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University of Science and Technology of China USTC
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University of Science and Technology of China USTC
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Abstract

The present invention relates to X-ray phase contrast imaging technical field, disclose a kind of method that X-ray machine outgoing spectrum is carried out bandpass filtering, the method is to be directed at X-ray machine anode exit facet by the plexiglass box filling with liquor kalii iodide or IodineSodium Solution, make the liquor kalii iodide in plexiglass box or IodineSodium Solution that cone-beam X-ray that X-ray machine anode send can be completely covered, utilize liquor kalii iodide or the IodineSodium Solution diversity to different-energy section X-ray attenuation ability, filter the energetic portions in X-ray machine outgoing spectrum and mental retardation part.Filter the energetic portions in X-ray machine outgoing spectrum, improve the displacement curve contrast of conventional X-ray source raster phase contrast imaging, add sensitivity and accuracy that phase information is extracted.Filter the mental retardation part of X-ray machine emergent ray, reduce the radiation damage of sample, eliminate reconstruction artifact, add the image quality of X-ray raster phase contrast system.

Description

A kind of method that X-ray machine outgoing spectrum is carried out bandpass filtering
Technical field
The present invention relates to X-ray phase contrast imaging technical field, especially one X-ray machine is gone out Penetrate the method that spectrum carries out bandpass filtering.
Background technology
In the raster phase contrast imaging of conventional X-ray source, the grizzly bar of grating is typically made of gold, permissible Play the effect absorbing X-ray.Ideally, the X-ray being radiated at grizzly bar part can be complete Entirely absorbed, but the grating that in a practical situation, grizzly bar is thicker, the cycle is less is often difficult to development adds Work.
The ray that X-ray machine sends is the continuous X-ray spectrum that wavelength does not waits, and uses the grizzly bar of grating in test The middle mental retardation part of spectrum can be fully absorbed, but the most micro-to the attenuation of energetic portions ray Weak.These, through the high-energy ray of grating grizzly bar, can be substantially reduced the displacement curve contrast of imaging system Degree, and displacement curve contrast be in the test of conventional X-ray source raster phase contrast imaging very Important parameter, it directly determines sensitivity and the accuracy of refraction information retrieval[1,2].Therefore, X The energetic portions of ray machine outgoing spectrum can have a strong impact on the performance of raster phase contrast imaging system.
Meanwhile, the mental retardation part of X-ray machine outgoing spectrum also can reduce the performance of system.At conventional X-ray In the raster phase contrast imaging of source, owing to the penetration capacity of low energy ray is more weak, major part low energy ray Can remain in sample, this considerably increases the radiation damage of experimental subject.Carrying out 3-D view weight When building, the bunch hardening phenomenon that low energy ray causes can cause obvious artifact, and artifact can obscure tomography Image, cause the loss of information[3].At present in scientific research and commercial Application, X-ray machine emergent light Low energy ray in spectrum is mainly filtered by copper sheet, aluminium flake[4]
Incorporated by reference document:
[1] Wang Zhentian, " conventional X-ray source grating image correlation technique and technical research ", Tsing-Hua University Doctor of engineering academic dissertation, the 37-41 page, in April, 2010.
[2] A.Sarapata, J.Stayman, M.Finkenthal, J.Siewerdsen, F.Pfeiffer, and D.Stutman, " High energy X-ray phase contrast CT using glancing-angle Grating interferometers, " Medical Physics, vo1.41, p.021904,2014.
[3] V Revol, C.Kottler, R.Kaufmann, U.Straumann, and C.Urban, ”Noise analysis of grating-based X-ray differential phase contrast imaging,” Review of Scientific Instruments, vo1.81, p.073709,2010.
[4] Zhang Jun, Li Lei, Zhang Feng, Lu Lizhong, Yan Bin, " X ray CT beam hardening correction side Method is summarized, " CT theory and application research, vol.1, p.033,2013.
Summary of the invention
(1) to solve the technical problem that
In view of this, present invention is primarily targeted at offer one X-ray machine outgoing spectrum is carried The method of pass filter, to filter the energetic portions of X-ray machine outgoing spectrum, improves conventional X-ray source light The displacement curve contrast of grid phase contrast imaging, increases sensitivity and accuracy that phase information is extracted, And filter the mental retardation part of X-ray machine emergent ray, reduce the radiation damage of sample, remove and rebuild artifact, Increase the image quality of X-ray raster phase contrast system.
(2) technical scheme
For reaching above-mentioned purpose, the invention provides one and X-ray machine outgoing spectrum is carried out bandpass filtering Method, the method is to fill with plexiglass box and the X-ray of liquor kalii iodide or IodineSodium Solution Machine anode exit facet is directed at, and makes the liquor kalii iodide in plexiglass box or IodineSodium Solution energy completely Cover the cone-beam X-ray that X-ray machine anode sends, utilize liquor kalii iodide or IodineSodium Solution to not The diversity of co-energy section of X-ray attenuation ability, filters the high energy portion in X-ray machine outgoing spectrum Divide and mental retardation part.
In such scheme, the tube voltage of described X-ray machine is 50KV, the scope of X-ray machine outgoing spectrum It is 10~50KeV.In described X-ray machine outgoing spectrum, energetic portions is 33.16~50KeV, mental retardation Part is 0~25KeV.
In such scheme, described plexiglass box be the poly (methyl methacrylate) plate by 0.2 millimeters thick bonding and Becoming, inside dimension is 10 cm x 10 cm x 0.1 centimetre.
In such scheme, described liquor kalii iodide is to be dissolved in 20 milliliters by 20 grams of white potassium iodide powder Water is prepared from, and liquor kalii iodide is 0.1 centimetre to the decay absorber thickness of X-ray.
In such scheme, described IodineSodium Solution is to be dissolved in 20 milliliters of water systems by 30 grams of sodium iodide powder For forming, IodineSodium Solution is 0.1 centimetre to the decay absorber thickness of X-ray.
(3) beneficial effect
The when that X-ray machine voltage being 50KV, the X-ray that X-ray machine anode sends is molten through potassium iodide Liquid or the bandpass filtering of IodineSodium Solution, in raster phase contrast imaging is tested, mainly have following two Individual advantage.
1, the high energy of outgoing spectrum is significantly absorbed due to the iodine in liquor kalii iodide or IodineSodium Solution Partly (33.16~50KeV), and this part of high-energy ray has had a strong impact on displacement curve contrast just. Grating grizzly bar thickness is 50um when, the displacement curve contrast that test records is by 10% (mistake Before filter) rise to 25% (after filtration).The raising of displacement curve contrast can dramatically increase phase place letter The sensitivity of breath extraction and accuracy.In the case of identical image quality requires, if displacement curve Contrast is higher, then can use less phase stepping step number and time of exposure in test, thus The radiation dose that test sample accepts can be reduced.
2, X-ray machine outgoing spectrum can substantially be filtered due to the iodine in liquor kalii iodide or IodineSodium Solution In mental retardation partial x-ray (0~25KeV), in experiment, the X-ray after filtration is almost without residual In sample, therefore, the radiation damage of sample is controlled effectively.Meanwhile, bunch hardening Phenomenon there's almost no, and during later image three-dimensional reconstruction, ring artifact is basically eliminated.
3, the method that X-ray machine outgoing spectrum is carried out bandpass filtering that the present invention provides, filters X-ray Energetic portions in machine outgoing spectrum, the displacement that improve conventional X-ray source raster phase contrast imaging is bent Line contrast, adds sensitivity and accuracy that phase information is extracted;Filter X-ray machine emergent ray Mental retardation part, reduce the radiation damage of sample, eliminate reconstruction artifact, add X-ray light The image quality of grid phase contrast system.
Accompanying drawing explanation
Fig. 1 is the schematic diagram that X-ray machine outgoing spectrum carries out bandpass filtering according to the embodiment of the present invention, Wherein, black curve is the linear of KI solution (density is 1.8g/ml) X-ray short to different-energy Absorptance, the curve that solid circles symbol represents is the outgoing spectrum (tube voltage is 50KV) of X-ray machine, The curve that filled squares symbol represents is the spectrum after bandpass filtering.
Fig. 2 is the device that X-ray machine outgoing spectrum carries out bandpass filtering according to the embodiment of the present invention Structural representation, wherein, 1 is optical table, 2 and 6 three-dimensional optical precision displacement table, and 3 is X Ray machine, 4 is potassium iodide or IodineSodium Solution, and 5 is plexiglass box.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearer, below in conjunction with concrete real Execute example, and referring to the drawings, the present invention is described in more detail.
As depicted in figs. 1 and 2, what the present invention provided carries out bandpass filtering to X-ray machine outgoing spectrum Method, is to be gone out with X-ray machine anode by the plexiglass box filling with liquor kalii iodide or IodineSodium Solution Penetrate in the face of accurate, make the liquor kalii iodide in plexiglass box or IodineSodium Solution that X-ray can be completely covered The cone-beam X-ray that machine anode sends, utilizes liquor kalii iodide or IodineSodium Solution to different-energy section X The diversity of ray attenuation ability, filters the energetic portions in X-ray machine outgoing spectrum and mental retardation part.
Wherein, the tube voltage of X-ray machine is 50KV, X-ray machine outgoing spectrum in the range of 10~50KeV, Wherein energetic portions is 33.16~50KeV, and mental retardation part is 0~25KeV.Plexiglass box be by The poly (methyl methacrylate) plate of 0.2 millimeters thick is bonding to be formed, and inside dimension is 10 cm x 10 cm x 0.1 li Rice.Liquor kalii iodide is to be dissolved in 20 milliliters of water by 20 grams of white potassium iodide powder to be prepared from, iodate Potassium solution is 0.1 centimetre to the decay absorber thickness of X-ray.IodineSodium Solution is by 30 grams of iodate Sodium powder is dissolved in 20 milliliters of water and is prepared from, and the decay absorber thickness of X-ray is by IodineSodium Solution 0.1 centimetre.
When the x-ray photon energy of the liquor kalii iodide being incident in plexiglass box is positioned at The when of 0~33.16KeV scope, along with the rising of photon energy, liquor kalii iodide is to X-ray Linear absorption coefficient is more and more less.When x-ray photon energy reaches 33.16KeV, (K of iodine absorbs Limit) when, the absorption of X-ray is steeply risen by liquor kalii iodide.Then, continuing along with energy Continuous raising, the absorbability of X-ray is weakened by liquor kalii iodide the most gradually.
It is 50KV at X-ray machine voltage, the when that tube current being 22.5mA, the emergent light of X-ray machine Spectral limit is about 10~50KeV, and the average energy of outgoing spectrum is about 30KeV, such as the reality in Fig. 1 Shown in the curve that heart circle signs represents.Black curve in Fig. 1 is that (density is liquor kalii iodide 1.8g/ml) the linear absorption coefficient to different-energy section X-ray, the song that filled squares symbol represents Line is the spectrum after bandpass filtering.Can be seen that the bandpass filtering through liquor kalii iodide, X-ray machine goes out Energetic portions (33.16~50KeV) and the mental retardation part (10~25KeV) of penetrating spectrum have obtained obvious mistake Filter.Spectrum after bandpass filtering, provides superior ray for raster phase contrast imaging below.
Referring again to Fig. 2, wherein 1 is optical table, and 2 and 6 is that the three-dimensional optical that two sets assemble is accurate Displacement platform, can realize linear motion in tri-directions of X, Y and Z respectively, pass through step motor control Device carries out motor control to them.Utilize special mechanical part, X-ray machine and plexiglass box Being separately fixed on 2 and 6, X-ray machine is by circulating water.Plexiglass box is by 0.2 millimeter Thick poly (methyl methacrylate) plate is bonding to be formed, and inside dimension is 10 cm x 10 cm x 0.1 centimetre, organic Glass container fills with liquor kalii iodide or IodineSodium Solution.Liquor kalii iodide is by 20 grams of white iodine Change potassium powder is dissolved in 20 milliliters of water and is prepared from, the liquor kalii iodide decay absorber thickness to X-ray It it is 0.1 centimetre.IodineSodium Solution is to be dissolved in 20 milliliters of water by 30 grams of sodium iodide powder to be prepared from, IodineSodium Solution is 0.1 centimetre to the decay absorber thickness of X-ray.
Optical table, controllor for step-by-step motor are respectively positioned in radiation protection lead room, the controller of X-ray machine It is positioned at outside lead room.X-ray machine can be beaten with the motion of Non-follow control optical displacement platform, ray the when of closedown After opening, remotely can be controlled by computer.Through fine setting, make plexiglass box and X-ray machine anode exit facet is directed at, and so can ensure that liquor kalii iodide can be completely covered X-ray machine and send Cone-beam x-ray.
The tube voltage setting X-ray machine is 22.5mA as 50KV, tube current, now the going out of X-ray machine Penetrating spectral region and be about 10~50KeV, the average energy of ray is about 30KeV, such as the reality in Fig. 1 Shown in the curve that heart circle signs represents.Black curve in Fig. 1 is KI solution (density is 1.8g/m1) Linear absorption coefficient to different-energy section X-ray, the curve that filled squares symbol represents is that band is logical Filtered spectrum.Can be seen that the energetic portions (33.16~50KeV) of X-ray machine outgoing spectrum and low Part (10~25KeV) obvious filtration can be obtained.Through the X-ray of liquor kalii iodide bandpass filtering, Carrying out raster phase contrast imaging test, displacement curve contrast is improved, and bunch hardening phenomenon obtains Solving to basic, the image quality of conventional X-ray source raster phase contrast system is improved.
Particular embodiments described above, is carried out the purpose of the present invention, technical scheme and beneficial effect Further describe, be it should be understood that the foregoing is only the present invention specific embodiment and , be not limited to the present invention, all within the spirit and principles in the present invention, that is done any repaiies Change, equivalent, improvement etc., should be included within the scope of the present invention.

Claims (4)

1. the method that X-ray machine outgoing spectrum is carried out bandpass filtering, it is characterised in that the party Method is to fill with plexiglass box and the X-ray machine anode outgoing of liquor kalii iodide or IodineSodium Solution In the face of accurate, make the liquor kalii iodide in plexiglass box or IodineSodium Solution that X-ray machine can be completely covered The cone-beam X-ray that anode sends, utilizes liquor kalii iodide or IodineSodium Solution to different-energy section X The diversity of ray attenuation ability, filters the energetic portions in X-ray machine outgoing spectrum and mental retardation part;
Wherein, described liquor kalii iodide is to be dissolved in 20 milliliters of water by 20 grams of white potassium iodide powder to prepare Forming, liquor kalii iodide is 0.1 centimetre to the decay absorber thickness of X-ray;Described IodineSodium Solution Being to be dissolved in 20 milliliters of water by 30 grams of sodium iodide powder to be prepared from, X-ray is declined by IodineSodium Solution Subtracting absorber thickness is 0.1 centimetre.
The method that X-ray machine outgoing spectrum is carried out bandpass filtering the most according to claim 1, It is characterized in that, the tube voltage of described X-ray machine is 50KV, X-ray machine outgoing spectrum in the range of 10~50KeV.
The method that X-ray machine outgoing spectrum is carried out bandpass filtering the most according to claim 2, It is characterized in that, in described X-ray machine outgoing spectrum, energetic portions is 33.16~50KeV, mental retardation portion Dividing is 10~25KeV.
The method that X-ray machine outgoing spectrum is carried out bandpass filtering the most according to claim 1, It is characterized in that, described plexiglass box is that the poly (methyl methacrylate) plate by 0.2 millimeters thick is bonding to be formed, Inside dimension is 10 cm x 10 cm x 0.1 centimetre.
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