CN103903666B - A kind of method that X-ray machine outgoing spectrum is carried out bandpass filtering - Google Patents
A kind of method that X-ray machine outgoing spectrum is carried out bandpass filtering Download PDFInfo
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- CN103903666B CN103903666B CN201410148270.7A CN201410148270A CN103903666B CN 103903666 B CN103903666 B CN 103903666B CN 201410148270 A CN201410148270 A CN 201410148270A CN 103903666 B CN103903666 B CN 103903666B
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- ray machine
- outgoing spectrum
- liquor kalii
- spectrum
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- 238000001228 spectrum Methods 0.000 title claims abstract description 40
- 238000001914 filtration Methods 0.000 title claims abstract description 22
- 238000000034 method Methods 0.000 title claims abstract description 16
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 claims abstract description 30
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims abstract description 16
- 229920005372 Plexiglas® Polymers 0.000 claims abstract description 16
- 208000036626 Mental retardation Diseases 0.000 claims abstract description 14
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 claims description 17
- FVAUCKIRQBBSSJ-UHFFFAOYSA-M sodium iodide Chemical compound [Na+].[I-] FVAUCKIRQBBSSJ-UHFFFAOYSA-M 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 239000006096 absorbing agent Substances 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 8
- 229920003229 poly(methyl methacrylate) Polymers 0.000 claims description 4
- 239000004926 polymethyl methacrylate Substances 0.000 claims description 4
- 235000009518 sodium iodide Nutrition 0.000 claims description 3
- 238000006073 displacement reaction Methods 0.000 abstract description 13
- 238000003384 imaging method Methods 0.000 abstract description 13
- 230000005855 radiation Effects 0.000 abstract description 7
- 230000035945 sensitivity Effects 0.000 abstract description 5
- 241000216843 Ursus arctos horribilis Species 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 4
- 229910052740 iodine Inorganic materials 0.000 description 4
- 239000011630 iodine Substances 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- WTCBONOLBHEDIL-UHFFFAOYSA-M Sodium iodate Chemical compound [Na+].[O-]I(=O)=O WTCBONOLBHEDIL-UHFFFAOYSA-M 0.000 description 1
- 238000002083 X-ray spectrum Methods 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- JLKDVMWYMMLWTI-UHFFFAOYSA-M potassium iodate Chemical compound [K+].[O-]I(=O)=O JLKDVMWYMMLWTI-UHFFFAOYSA-M 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000003325 tomography Methods 0.000 description 1
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- Apparatus For Radiation Diagnosis (AREA)
Abstract
The present invention relates to X-ray phase contrast imaging technical field, disclose a kind of method that X-ray machine outgoing spectrum is carried out bandpass filtering, the method is to be directed at X-ray machine anode exit facet by the plexiglass box filling with liquor kalii iodide or IodineSodium Solution, make the liquor kalii iodide in plexiglass box or IodineSodium Solution that cone-beam X-ray that X-ray machine anode send can be completely covered, utilize liquor kalii iodide or the IodineSodium Solution diversity to different-energy section X-ray attenuation ability, filter the energetic portions in X-ray machine outgoing spectrum and mental retardation part.Filter the energetic portions in X-ray machine outgoing spectrum, improve the displacement curve contrast of conventional X-ray source raster phase contrast imaging, add sensitivity and accuracy that phase information is extracted.Filter the mental retardation part of X-ray machine emergent ray, reduce the radiation damage of sample, eliminate reconstruction artifact, add the image quality of X-ray raster phase contrast system.
Description
Technical field
The present invention relates to X-ray phase contrast imaging technical field, especially one X-ray machine is gone out
Penetrate the method that spectrum carries out bandpass filtering.
Background technology
In the raster phase contrast imaging of conventional X-ray source, the grizzly bar of grating is typically made of gold, permissible
Play the effect absorbing X-ray.Ideally, the X-ray being radiated at grizzly bar part can be complete
Entirely absorbed, but the grating that in a practical situation, grizzly bar is thicker, the cycle is less is often difficult to development adds
Work.
The ray that X-ray machine sends is the continuous X-ray spectrum that wavelength does not waits, and uses the grizzly bar of grating in test
The middle mental retardation part of spectrum can be fully absorbed, but the most micro-to the attenuation of energetic portions ray
Weak.These, through the high-energy ray of grating grizzly bar, can be substantially reduced the displacement curve contrast of imaging system
Degree, and displacement curve contrast be in the test of conventional X-ray source raster phase contrast imaging very
Important parameter, it directly determines sensitivity and the accuracy of refraction information retrieval[1,2].Therefore, X
The energetic portions of ray machine outgoing spectrum can have a strong impact on the performance of raster phase contrast imaging system.
Meanwhile, the mental retardation part of X-ray machine outgoing spectrum also can reduce the performance of system.At conventional X-ray
In the raster phase contrast imaging of source, owing to the penetration capacity of low energy ray is more weak, major part low energy ray
Can remain in sample, this considerably increases the radiation damage of experimental subject.Carrying out 3-D view weight
When building, the bunch hardening phenomenon that low energy ray causes can cause obvious artifact, and artifact can obscure tomography
Image, cause the loss of information[3].At present in scientific research and commercial Application, X-ray machine emergent light
Low energy ray in spectrum is mainly filtered by copper sheet, aluminium flake[4]。
Incorporated by reference document:
[1] Wang Zhentian, " conventional X-ray source grating image correlation technique and technical research ", Tsing-Hua University
Doctor of engineering academic dissertation, the 37-41 page, in April, 2010.
[2] A.Sarapata, J.Stayman, M.Finkenthal, J.Siewerdsen, F.Pfeiffer, and
D.Stutman, " High energy X-ray phase contrast CT using glancing-angle
Grating interferometers, " Medical Physics, vo1.41, p.021904,2014.
[3] V Revol, C.Kottler, R.Kaufmann, U.Straumann, and C.Urban,
”Noise analysis of grating-based X-ray differential phase contrast imaging,”
Review of Scientific Instruments, vo1.81, p.073709,2010.
[4] Zhang Jun, Li Lei, Zhang Feng, Lu Lizhong, Yan Bin, " X ray CT beam hardening correction side
Method is summarized, " CT theory and application research, vol.1, p.033,2013.
Summary of the invention
(1) to solve the technical problem that
In view of this, present invention is primarily targeted at offer one X-ray machine outgoing spectrum is carried
The method of pass filter, to filter the energetic portions of X-ray machine outgoing spectrum, improves conventional X-ray source light
The displacement curve contrast of grid phase contrast imaging, increases sensitivity and accuracy that phase information is extracted,
And filter the mental retardation part of X-ray machine emergent ray, reduce the radiation damage of sample, remove and rebuild artifact,
Increase the image quality of X-ray raster phase contrast system.
(2) technical scheme
For reaching above-mentioned purpose, the invention provides one and X-ray machine outgoing spectrum is carried out bandpass filtering
Method, the method is to fill with plexiglass box and the X-ray of liquor kalii iodide or IodineSodium Solution
Machine anode exit facet is directed at, and makes the liquor kalii iodide in plexiglass box or IodineSodium Solution energy completely
Cover the cone-beam X-ray that X-ray machine anode sends, utilize liquor kalii iodide or IodineSodium Solution to not
The diversity of co-energy section of X-ray attenuation ability, filters the high energy portion in X-ray machine outgoing spectrum
Divide and mental retardation part.
In such scheme, the tube voltage of described X-ray machine is 50KV, the scope of X-ray machine outgoing spectrum
It is 10~50KeV.In described X-ray machine outgoing spectrum, energetic portions is 33.16~50KeV, mental retardation
Part is 0~25KeV.
In such scheme, described plexiglass box be the poly (methyl methacrylate) plate by 0.2 millimeters thick bonding and
Becoming, inside dimension is 10 cm x 10 cm x 0.1 centimetre.
In such scheme, described liquor kalii iodide is to be dissolved in 20 milliliters by 20 grams of white potassium iodide powder
Water is prepared from, and liquor kalii iodide is 0.1 centimetre to the decay absorber thickness of X-ray.
In such scheme, described IodineSodium Solution is to be dissolved in 20 milliliters of water systems by 30 grams of sodium iodide powder
For forming, IodineSodium Solution is 0.1 centimetre to the decay absorber thickness of X-ray.
(3) beneficial effect
The when that X-ray machine voltage being 50KV, the X-ray that X-ray machine anode sends is molten through potassium iodide
Liquid or the bandpass filtering of IodineSodium Solution, in raster phase contrast imaging is tested, mainly have following two
Individual advantage.
1, the high energy of outgoing spectrum is significantly absorbed due to the iodine in liquor kalii iodide or IodineSodium Solution
Partly (33.16~50KeV), and this part of high-energy ray has had a strong impact on displacement curve contrast just.
Grating grizzly bar thickness is 50um when, the displacement curve contrast that test records is by 10% (mistake
Before filter) rise to 25% (after filtration).The raising of displacement curve contrast can dramatically increase phase place letter
The sensitivity of breath extraction and accuracy.In the case of identical image quality requires, if displacement curve
Contrast is higher, then can use less phase stepping step number and time of exposure in test, thus
The radiation dose that test sample accepts can be reduced.
2, X-ray machine outgoing spectrum can substantially be filtered due to the iodine in liquor kalii iodide or IodineSodium Solution
In mental retardation partial x-ray (0~25KeV), in experiment, the X-ray after filtration is almost without residual
In sample, therefore, the radiation damage of sample is controlled effectively.Meanwhile, bunch hardening
Phenomenon there's almost no, and during later image three-dimensional reconstruction, ring artifact is basically eliminated.
3, the method that X-ray machine outgoing spectrum is carried out bandpass filtering that the present invention provides, filters X-ray
Energetic portions in machine outgoing spectrum, the displacement that improve conventional X-ray source raster phase contrast imaging is bent
Line contrast, adds sensitivity and accuracy that phase information is extracted;Filter X-ray machine emergent ray
Mental retardation part, reduce the radiation damage of sample, eliminate reconstruction artifact, add X-ray light
The image quality of grid phase contrast system.
Accompanying drawing explanation
Fig. 1 is the schematic diagram that X-ray machine outgoing spectrum carries out bandpass filtering according to the embodiment of the present invention,
Wherein, black curve is the linear of KI solution (density is 1.8g/ml) X-ray short to different-energy
Absorptance, the curve that solid circles symbol represents is the outgoing spectrum (tube voltage is 50KV) of X-ray machine,
The curve that filled squares symbol represents is the spectrum after bandpass filtering.
Fig. 2 is the device that X-ray machine outgoing spectrum carries out bandpass filtering according to the embodiment of the present invention
Structural representation, wherein, 1 is optical table, 2 and 6 three-dimensional optical precision displacement table, and 3 is X
Ray machine, 4 is potassium iodide or IodineSodium Solution, and 5 is plexiglass box.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearer, below in conjunction with concrete real
Execute example, and referring to the drawings, the present invention is described in more detail.
As depicted in figs. 1 and 2, what the present invention provided carries out bandpass filtering to X-ray machine outgoing spectrum
Method, is to be gone out with X-ray machine anode by the plexiglass box filling with liquor kalii iodide or IodineSodium Solution
Penetrate in the face of accurate, make the liquor kalii iodide in plexiglass box or IodineSodium Solution that X-ray can be completely covered
The cone-beam X-ray that machine anode sends, utilizes liquor kalii iodide or IodineSodium Solution to different-energy section X
The diversity of ray attenuation ability, filters the energetic portions in X-ray machine outgoing spectrum and mental retardation part.
Wherein, the tube voltage of X-ray machine is 50KV, X-ray machine outgoing spectrum in the range of 10~50KeV,
Wherein energetic portions is 33.16~50KeV, and mental retardation part is 0~25KeV.Plexiglass box be by
The poly (methyl methacrylate) plate of 0.2 millimeters thick is bonding to be formed, and inside dimension is 10 cm x 10 cm x 0.1 li
Rice.Liquor kalii iodide is to be dissolved in 20 milliliters of water by 20 grams of white potassium iodide powder to be prepared from, iodate
Potassium solution is 0.1 centimetre to the decay absorber thickness of X-ray.IodineSodium Solution is by 30 grams of iodate
Sodium powder is dissolved in 20 milliliters of water and is prepared from, and the decay absorber thickness of X-ray is by IodineSodium Solution
0.1 centimetre.
When the x-ray photon energy of the liquor kalii iodide being incident in plexiglass box is positioned at
The when of 0~33.16KeV scope, along with the rising of photon energy, liquor kalii iodide is to X-ray
Linear absorption coefficient is more and more less.When x-ray photon energy reaches 33.16KeV, (K of iodine absorbs
Limit) when, the absorption of X-ray is steeply risen by liquor kalii iodide.Then, continuing along with energy
Continuous raising, the absorbability of X-ray is weakened by liquor kalii iodide the most gradually.
It is 50KV at X-ray machine voltage, the when that tube current being 22.5mA, the emergent light of X-ray machine
Spectral limit is about 10~50KeV, and the average energy of outgoing spectrum is about 30KeV, such as the reality in Fig. 1
Shown in the curve that heart circle signs represents.Black curve in Fig. 1 is that (density is liquor kalii iodide
1.8g/ml) the linear absorption coefficient to different-energy section X-ray, the song that filled squares symbol represents
Line is the spectrum after bandpass filtering.Can be seen that the bandpass filtering through liquor kalii iodide, X-ray machine goes out
Energetic portions (33.16~50KeV) and the mental retardation part (10~25KeV) of penetrating spectrum have obtained obvious mistake
Filter.Spectrum after bandpass filtering, provides superior ray for raster phase contrast imaging below.
Referring again to Fig. 2, wherein 1 is optical table, and 2 and 6 is that the three-dimensional optical that two sets assemble is accurate
Displacement platform, can realize linear motion in tri-directions of X, Y and Z respectively, pass through step motor control
Device carries out motor control to them.Utilize special mechanical part, X-ray machine and plexiglass box
Being separately fixed on 2 and 6, X-ray machine is by circulating water.Plexiglass box is by 0.2 millimeter
Thick poly (methyl methacrylate) plate is bonding to be formed, and inside dimension is 10 cm x 10 cm x 0.1 centimetre, organic
Glass container fills with liquor kalii iodide or IodineSodium Solution.Liquor kalii iodide is by 20 grams of white iodine
Change potassium powder is dissolved in 20 milliliters of water and is prepared from, the liquor kalii iodide decay absorber thickness to X-ray
It it is 0.1 centimetre.IodineSodium Solution is to be dissolved in 20 milliliters of water by 30 grams of sodium iodide powder to be prepared from,
IodineSodium Solution is 0.1 centimetre to the decay absorber thickness of X-ray.
Optical table, controllor for step-by-step motor are respectively positioned in radiation protection lead room, the controller of X-ray machine
It is positioned at outside lead room.X-ray machine can be beaten with the motion of Non-follow control optical displacement platform, ray the when of closedown
After opening, remotely can be controlled by computer.Through fine setting, make plexiglass box and
X-ray machine anode exit facet is directed at, and so can ensure that liquor kalii iodide can be completely covered X-ray machine and send
Cone-beam x-ray.
The tube voltage setting X-ray machine is 22.5mA as 50KV, tube current, now the going out of X-ray machine
Penetrating spectral region and be about 10~50KeV, the average energy of ray is about 30KeV, such as the reality in Fig. 1
Shown in the curve that heart circle signs represents.Black curve in Fig. 1 is KI solution (density is 1.8g/m1)
Linear absorption coefficient to different-energy section X-ray, the curve that filled squares symbol represents is that band is logical
Filtered spectrum.Can be seen that the energetic portions (33.16~50KeV) of X-ray machine outgoing spectrum and low
Part (10~25KeV) obvious filtration can be obtained.Through the X-ray of liquor kalii iodide bandpass filtering,
Carrying out raster phase contrast imaging test, displacement curve contrast is improved, and bunch hardening phenomenon obtains
Solving to basic, the image quality of conventional X-ray source raster phase contrast system is improved.
Particular embodiments described above, is carried out the purpose of the present invention, technical scheme and beneficial effect
Further describe, be it should be understood that the foregoing is only the present invention specific embodiment and
, be not limited to the present invention, all within the spirit and principles in the present invention, that is done any repaiies
Change, equivalent, improvement etc., should be included within the scope of the present invention.
Claims (4)
1. the method that X-ray machine outgoing spectrum is carried out bandpass filtering, it is characterised in that the party
Method is to fill with plexiglass box and the X-ray machine anode outgoing of liquor kalii iodide or IodineSodium Solution
In the face of accurate, make the liquor kalii iodide in plexiglass box or IodineSodium Solution that X-ray machine can be completely covered
The cone-beam X-ray that anode sends, utilizes liquor kalii iodide or IodineSodium Solution to different-energy section X
The diversity of ray attenuation ability, filters the energetic portions in X-ray machine outgoing spectrum and mental retardation part;
Wherein, described liquor kalii iodide is to be dissolved in 20 milliliters of water by 20 grams of white potassium iodide powder to prepare
Forming, liquor kalii iodide is 0.1 centimetre to the decay absorber thickness of X-ray;Described IodineSodium Solution
Being to be dissolved in 20 milliliters of water by 30 grams of sodium iodide powder to be prepared from, X-ray is declined by IodineSodium Solution
Subtracting absorber thickness is 0.1 centimetre.
The method that X-ray machine outgoing spectrum is carried out bandpass filtering the most according to claim 1,
It is characterized in that, the tube voltage of described X-ray machine is 50KV, X-ray machine outgoing spectrum in the range of
10~50KeV.
The method that X-ray machine outgoing spectrum is carried out bandpass filtering the most according to claim 2,
It is characterized in that, in described X-ray machine outgoing spectrum, energetic portions is 33.16~50KeV, mental retardation portion
Dividing is 10~25KeV.
The method that X-ray machine outgoing spectrum is carried out bandpass filtering the most according to claim 1,
It is characterized in that, described plexiglass box is that the poly (methyl methacrylate) plate by 0.2 millimeters thick is bonding to be formed,
Inside dimension is 10 cm x 10 cm x 0.1 centimetre.
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