CN103863984A - Sterile filling infusion system with automatic liquid feeding control - Google Patents
Sterile filling infusion system with automatic liquid feeding control Download PDFInfo
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- CN103863984A CN103863984A CN201210540852.0A CN201210540852A CN103863984A CN 103863984 A CN103863984 A CN 103863984A CN 201210540852 A CN201210540852 A CN 201210540852A CN 103863984 A CN103863984 A CN 103863984A
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Abstract
The invention relates to a sterile filling infusion system with automatic liquid feeding control. The sterile filling infusion system comprises: a peristaltic pump, a terminal filter, a bench scale, an air filter, an infusion tube, a filling pump and a liquid storage tank, wherein the liquid storage tank comprises an upper cover and a tank body, the liquid inlet of the liquid storage tank is positioned on the upper end of the tank body, and is connected with the outlet of the terminal filter, the liquid outlet of the liquid storage tank is positioned on the lowest end of the tank body, and is connected with the filling pump through the infusion tube, the upper cover of the liquid storage tank is connected with the air filter, and the liquid storage tank is placed on the bench scale. With the agent filling infusion system of the present invention, the liquid feeding can be automatically controlled, the staff operation can be saved, the pollution during the sterile operation process can be reduced, and the product quality can be ensured.
Description
Technical field
The present invention relates to a kind of filling transfusion system, be specifically related to a kind of filling transfusion system that not only can automatically control feed liquor but also can reduce the quality of pollution in sterile working process, assurance product.
Background technology
Traditional liquid medicine filling transfusion system is mainly made up of peristaltic pump, inline final filter, bottle,suction, platform balance, air filter, hydraulic pipe, knockout and filling pump.The outlet of inline final filter is connected with bottle,suction inlet through hydraulic pipe, peristaltic pump is got liquid after starting and after inline final filter, is injected in bottle,suction, the connection air filter suitable for reading of bottle,suction, the liquid outlet of bottle,suction is connected with knockout with hydraulic pipe, knockout divides multiple little liquid outlets, one of them liquid outlet is used for carrying out exhaust bubble use, and remaining is connected with filling pump through primary infusion pipe, and filling pump liquid outlet has been connected all bulking systems through hydraulic pipe with filling syringe needle.There is in actual use following shortcoming in traditional liquid medicine filling transfusion system:
(1) bottle,suction liquid in-out bottleneck is easily broken, if there is especially little cut to find not in time, is easy to the little glass fragment producing to bring in product;
(2) for the opacus product of needs, bottle,suction in use also needs to increase a gobo, and gobo must carry out washing and sterilizing and could use;
(3) interface of knockout is more, and clean time dead angle more, the installation before sterilizing to pay special attention to install tightness, if there is leakage situation, returns and re-start washing and sterilizing, consume the time of at least 2 hours;
(4) be filled to final stage, in bottle,suction, remaining liquid will someone have been held, and will control height and angle, approximately wants the time of 10 minutes, filling on one side, on one side by clean the liquid control of the inside.
Summary of the invention
For above-mentioned defect, the object of the present invention is to provide a kind of not only can automatically control feed liquor and also can saving personnel operation, reduce in sterile working process the filling transfusion system that pollutes, guarantees product design.
For solving the problems of the technologies described above, the present invention is by the following technical solutions: a kind of sterile filling transfusion system of automatic control feed liquor, comprise peristaltic pump, inline final filter, platform balance, air filter, hydraulic pipe and filling pump, it is characterized by and further comprise fluid reservoir, fluid reservoir is made up of upper cover and tank body, fluid reservoir inlet is positioned at tank body upper end, be connected with the outlet of inline final filter through hydraulic pipe, the liquid outlet of fluid reservoir is positioned at tank body bottom, be connected with filling pump through hydraulic pipe, the upper cover of fluid reservoir is connected with air filter, and fluid reservoir is placed on platform balance.
Fluid reservoir adopts corrosion-resistant steel to make, and has not only avoided traditional bottle,suction liquid in-out mouth easily broken, may bring little glass fragment into problem in product, and avoid using gobo, has guaranteed to have the quality of opacus condition product.
The liquid outlet of fluid reservoir is connected with filling pump with hydraulic pipe, and traditional bottle,suction and knockout are united two into one and make fluid reservoir, and one side personnel have reduced the installation of two interfaces while installation, reduced artificial opportunities for contamination; Traditional knockout interface is more on the other hand, and clean time dead angle more, the installation before sterilizing to pay special attention to install tightness, if there is leakage situation, returns and re-start washing and sterilizing, consume the time of at least 2 hours.After transformation, the tank deck mouth of fluid reservoir is done greatly, tank interior can be cleaned thoroughly.
Platform balance arranges control parameter, and when the liquid in fluid reservoir weighs up while being less than minimum through platform balance, platform balance can send signal and automatically start peristaltic pump, and liquid is injected in fluid reservoir; When the liquid in fluid reservoir weighs up while reaching peak through platform balance, peristaltic pump quits work, and has realized automation mechanized operation and the control of filling transfusion system.
A kind of sterile filling transfusion system of automatic control feed liquor, comprise peristaltic pump, inline final filter, air filter, hydraulic pipe fluid reservoir, platform balance and filling pump, fluid reservoir is placed on platform balance, and the liquid that peristaltic pump is got after starting enters fluid reservoir through inline final filter by the inlet of fluid reservoir tank body upper end.When the liquid in fluid reservoir weighs up while being less than minimum through platform balance, platform balance can send signal and automatically start peristaltic pump, and liquid is injected in fluid reservoir; When the liquid in fluid reservoir weighs up while reaching peak through platform balance, peristaltic pump quits work.Liquid in fluid reservoir is connected with filling pump through hydraulic pipe from tank body liquid outlet bottom, and filling pump liquid outlet has been connected all bulking systems through hydraulic pipe with filling syringe needle.
Compared with traditional liquid medicine filling transfusion system, liquid medicine filling transfusion system provided by the invention not only can automatically control feed liquor and also can saving personnel operation, reduce in sterile working process the quality of polluting, guaranteeing product.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of traditional filling transfusion system.
Fig. 2 is schematic diagram of the present invention.
Fig. 3 is the local enlarged diagram of fluid reservoir of the present invention.
Marginal data: 1, peristaltic pump; 2, hydraulic pipe; 3, inline final filter; 4, platform balance; 5, bottle,suction; 6, air filter; 7, filling pump; 8, knockout; 9, fluid reservoir; 10, inlet; 11, tank body; 12, upper cover; 13, liquid outlet.
The specific embodiment
Below with reference to specific embodiment and Figure of description, the present invention is described in further details.
A sterile filling transfusion system for automatic control feed liquor, comprises peristaltic pump, inline final filter, air filter, hydraulic pipe fluid reservoir, platform balance and filling pump, and fluid reservoir is placed on platform balance.The liquid that peristaltic pump is got after starting enters fluid reservoir through inline final filter by the inlet of fluid reservoir tank body upper end.When the liquid in fluid reservoir weighs up while being less than minimum through platform balance, platform balance can send signal and automatically start peristaltic pump, and liquid is injected in fluid reservoir; When the liquid in fluid reservoir weighs up while reaching peak through platform balance, peristaltic pump quits work.Liquid in fluid reservoir is connected with filling pump through hydraulic pipe from tank body liquid outlet bottom, and filling pump liquid outlet has been connected all bulking systems through hydraulic pipe with filling syringe needle.
Claims (5)
1. a sterile filling transfusion system of automatically controlling feed liquor, comprises peristaltic pump, inline final filter, platform balance, air filter, hydraulic pipe and filling pump, it is characterized by and further comprises fluid reservoir.
2. filling transfusion system according to claim 1, is characterized by fluid reservoir and is made up of upper cover and tank body.
3. filling transfusion system according to claim 1, it is characterized by fluid reservoir inlet and be positioned at tank body upper end, be connected with the outlet of inline final filter through hydraulic pipe, the liquid outlet of fluid reservoir is positioned at tank body bottom, be connected with filling pump through hydraulic pipe, the upper cover of fluid reservoir is connected with air filter.
4. filling transfusion system according to claim 1, is characterized by fluid reservoir and adopts corrosion-resistant steel to make.
5. filling transfusion system according to claim 1, is characterized by fluid reservoir and is placed on platform balance.
Priority Applications (1)
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CN201210540852.0A CN103863984A (en) | 2012-12-14 | 2012-12-14 | Sterile filling infusion system with automatic liquid feeding control |
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CN201210540852.0A CN103863984A (en) | 2012-12-14 | 2012-12-14 | Sterile filling infusion system with automatic liquid feeding control |
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CN103863984A true CN103863984A (en) | 2014-06-18 |
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CN201210540852.0A Pending CN103863984A (en) | 2012-12-14 | 2012-12-14 | Sterile filling infusion system with automatic liquid feeding control |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107840297A (en) * | 2016-09-18 | 2018-03-27 | 武汉中原瑞德生物制品有限责任公司 | Liquid filling system and there is its Soup filling machine |
CN111184636A (en) * | 2018-11-14 | 2020-05-22 | 正大天晴药业集团南京顺欣制药有限公司 | Preparation of pharmaceutical composition containing recombinant protein |
CN112125260A (en) * | 2020-09-22 | 2020-12-25 | 天津中逸安健生物科技有限公司 | Suspension liquid medicine filling pipeline system containing aluminum adjuvant and method using system |
Citations (6)
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NL7806249A (en) * | 1978-06-08 | 1979-07-31 | Gist Brocades Nv | Constant head filling appts. for medicine bottles - has filling needles which can be sterilised in situ |
CN201105985Y (en) * | 2007-08-30 | 2008-08-27 | 泰山集团泰安市普瑞特机械制造有限公司 | Aseptic loading, storing and discharging system for materials like fruit juice |
CN101704495A (en) * | 2009-10-30 | 2010-05-12 | 东莞石龙津威饮料食品有限公司 | Method and equipment for vacuum quantitative filling of filling and sealing machine |
CN201990469U (en) * | 2011-03-25 | 2011-09-28 | 潍坊金瑞生物科技有限公司 | Automatic filling machine for medicinal liquids |
CN202124134U (en) * | 2011-06-14 | 2012-01-25 | 绿雪生物工程(深圳)有限公司 | Automatic yoghourt packaging system |
CN202226634U (en) * | 2011-09-21 | 2012-05-23 | 山东荣邦化工有限公司 | Full-automatic pesticide filling machine |
-
2012
- 2012-12-14 CN CN201210540852.0A patent/CN103863984A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7806249A (en) * | 1978-06-08 | 1979-07-31 | Gist Brocades Nv | Constant head filling appts. for medicine bottles - has filling needles which can be sterilised in situ |
CN201105985Y (en) * | 2007-08-30 | 2008-08-27 | 泰山集团泰安市普瑞特机械制造有限公司 | Aseptic loading, storing and discharging system for materials like fruit juice |
CN101704495A (en) * | 2009-10-30 | 2010-05-12 | 东莞石龙津威饮料食品有限公司 | Method and equipment for vacuum quantitative filling of filling and sealing machine |
CN201990469U (en) * | 2011-03-25 | 2011-09-28 | 潍坊金瑞生物科技有限公司 | Automatic filling machine for medicinal liquids |
CN202124134U (en) * | 2011-06-14 | 2012-01-25 | 绿雪生物工程(深圳)有限公司 | Automatic yoghourt packaging system |
CN202226634U (en) * | 2011-09-21 | 2012-05-23 | 山东荣邦化工有限公司 | Full-automatic pesticide filling machine |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107840297A (en) * | 2016-09-18 | 2018-03-27 | 武汉中原瑞德生物制品有限责任公司 | Liquid filling system and there is its Soup filling machine |
CN107840297B (en) * | 2016-09-18 | 2020-03-24 | 武汉中原瑞德生物制品有限责任公司 | Liquid filling system and liquid medicine filling machine with same |
CN111184636A (en) * | 2018-11-14 | 2020-05-22 | 正大天晴药业集团南京顺欣制药有限公司 | Preparation of pharmaceutical composition containing recombinant protein |
CN112125260A (en) * | 2020-09-22 | 2020-12-25 | 天津中逸安健生物科技有限公司 | Suspension liquid medicine filling pipeline system containing aluminum adjuvant and method using system |
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C53 | Correction of patent of invention or patent application | ||
CB02 | Change of applicant information |
Address after: 264003 Yantai hi tech Zone, Shandong venture Road No. 15 Applicant after: Shandong Luye Pharma Co., Ltd. Address before: 264003 Laishan, Shandong Province Bao Road, No. 9 District, No. Applicant before: Shandong Luye Pharma Co., Ltd. |
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WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140618 |