CN103826539B - Image processing system, radiographic apparatus and image processing method - Google Patents

Image processing system, radiographic apparatus and image processing method Download PDF

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Publication number
CN103826539B
CN103826539B CN201380001786.2A CN201380001786A CN103826539B CN 103826539 B CN103826539 B CN 103826539B CN 201380001786 A CN201380001786 A CN 201380001786A CN 103826539 B CN103826539 B CN 103826539B
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China
Prior art keywords
mentioned
image data
data
dimensional
position alignment
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CN201380001786.2A
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Chinese (zh)
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CN103826539A (en
Inventor
桥本新
桥本新一
大内启之
坂口卓弥
渊上航
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Canon Medical Systems Corp
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Toshiba Medical Systems Corp
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/02—Devices for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computerised tomographs
    • A61B6/032—Transmission computed tomography [CT]
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
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    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/12—Devices for detecting or locating foreign bodies
    • A—HUMAN NECESSITIES
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    • A61B6/44—Constructional features of apparatus for radiation diagnosis
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    • A61B6/46—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment with special arrangements for interfacing with the operator or the patient
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    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5238—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
    • A61B8/5246—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from the same or different imaging techniques, e.g. color Doppler and B-mode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5238—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image
    • A61B8/5261—Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for combining image data of patient, e.g. merging several images from different acquisition modes into one image combining images from different diagnostic modalities, e.g. ultrasound and X-ray
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
    • A61B2034/2046—Tracking techniques
    • A61B2034/2048—Tracking techniques using an accelerometer or inertia sensor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/44—Constructional features of apparatus for radiation diagnosis
    • A61B6/4429—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units
    • A61B6/4435—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure
    • A61B6/4441—Constructional features of apparatus for radiation diagnosis related to the mounting of source units and detector units the source unit and the detector unit being coupled by a rigid structure the rigid structure being a C-arm or U-arm
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10004—Still image; Photographic image
    • G06T2207/10012—Stereo images
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    • G06T2207/10072—Tomographic images
    • G06T2207/10081—Computed x-ray tomography [CT]
    • G—PHYSICS
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    • G06T2207/10—Image acquisition modality
    • G06T2207/10116—X-ray image
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    • G06T2207/10116—X-ray image
    • G06T2207/10121—Fluoroscopy
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    • G06T2207/10132—Ultrasound image
    • G06T2207/10136—3D ultrasound image
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
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    • G06T2207/30004—Biomedical image processing
    • G06T2207/30048—Heart; Cardiac

Abstract

The image processing system of embodiment possesses the 1st position alignment portion, output unit, the 2nd position alignment portion and display part.1st position alignment portion carries out the position alignment between the 1st three-dimensional medical image data and the 2nd three-dimensional medical image data.Output unit above-mentioned 1st three-dimensional medical image data and the above-mentioned 2nd three-dimensional medical image data will be addition of position alignment information after data or generated data after the 1st three-dimensional medical image data and the 2nd three-dimensional medical image data position are directed at and synthesize export as output data.2nd position alignment portion receives above-mentioned output data, carries out the position alignment between the above-mentioned 2nd three-dimensional medical image data and 1 or multiple X-ray image data.Display part shows the above-mentioned 1st three-dimensional medical image data position alignment in the view data of X-ray image data according to position alignment result.

Description

Image processing system, radiographic apparatus and image processing method
Technical field
Embodiments of the present invention relate to image processing system, radiographic apparatus and image Processing method.
Background technology
In the past, as one of heart failure therapy method it is known that have cardiac resynchronization therapy (CRT: Cardiac Resynchronization Therapy).CRT is by electricity thorn in heart The propagation swashed there occurs the position (hereinafter referred to as " delay position ") of delay, indwelling heart The electrode (pacing lead) of pacemaker, thus improve the asynchronous of cardiac motion, make the heart Dirty pumps out the functional rehabilitation therapy to normal condition.In a crt, doctor is with reference to logical Cross the radioscopic image that radiographic apparatus perspective photography obtains, at range delay position Nearest venous indwelling electrode.
Postpone position in the past such as according to EP(Electrophysiology) information diagnose, Mapped by EP in recent years and diagnose.The most in recent years it is known that postpone position and may be able to pass through The analysis of the Noninvasive employing diagnostic ultrasound equipment diagnoses.I.e., in recent years, logical Cross method that heart wall motion is analyzed by ultrasonic cardiography quantitatively just practical, In this analysis method, it is possible to show at the endomyocardial of ultrasonography or endomyocardial with outer Between film, the index (such as, strain etc.) of the heart wall motion of local is with the tone corresponding with value The analysis image mapped.Heart is the group that cardiac muscle moves due to mechanical vibration based on electricity irritation Knit, therefore, postpone position and can show which as the nonsynchronous position of heart wall motion in analyzing image (asynchronous position).But, CRT treatment is carried out under radioscopy, only by inciting somebody to action Above-mentioned analysis image is passed on as the priori information giving doctor when planned treatment, real On border, do not realize under the radioscopy carrying out CRT treatment, doctor being illustrated and staying Put the position of above-mentioned pacing lead.On the other hand, although achieve to radioscopy Under image on the overlapping technology showing other images, but owing to being difficult to differentiate the interior adventitia of heart wall Face, therefore, it is difficult to carry out radioscopic image and the position alignment analyzed between image, be i.e. difficult to into Position alignment between row radioscopic image and ultrasonography.
Prior art literature
Patent documentation
Patent documentation 1: Japanese Unexamined Patent Publication 2009-039429 publication
Summary of the invention
The problem to be solved in the present invention is, it is provided that one can differentiate logical under radioscopy Cross the image processing system at the position that ultrasonic diagnosis is determined, radiographic apparatus and figure As processing method.
The image processing system of embodiment possesses: the 1st position alignment portion, output unit, the 2nd Position alignment portion and display part.1st position alignment portion carries out the regulation tissue forceps to subject Position between the 1st three-dimensional medical image data and the 2nd three-dimensional medical image data that shadow obtains Alignment.Output unit will be three-dimensional medical to the above-mentioned 1st three-dimensional medical image data and the above-mentioned 2nd View data addition of the data of position alignment information or to the 1st three-dimensional medical image data The generated data carrying out position alignment with the 2nd three-dimensional medical image data and synthesize is as output Data export.2nd position alignment portion receives above-mentioned output data, carries out the above-mentioned 2nd three-dimensional Medical image data and by the above-mentioned regulation tissue of above-mentioned subject from 1 or multiple photography side Between 1 corresponding with photography direction or the multiple X-ray image data that obtain to photography Position alignment.Display part is according to above-mentioned 1st position alignment portion and above-mentioned 2nd position alignment portion Position alignment result, show above-mentioned 1st three-dimensional medical image data and above-mentioned regulation group View data after the X-ray image data position alignment knitted.At image according to above-mentioned composition Reason system, it is possible to differentiate the position determined by ultrasonic diagnosis under radioscopy.
Accompanying drawing explanation
Fig. 1 is the figure of the structure example representing the image processing system involved by the 1st embodiment.
Fig. 2 is the frame of the structure example representing the diagnostic ultrasound equipment involved by the 1st embodiment Figure.
Fig. 3 is the figure (1) for the analysis portion involved by the 1st embodiment is described.
Fig. 4 is the figure (2) for the analysis portion involved by the 1st embodiment is described.
Fig. 5 is the figure (3) for the analysis portion involved by the 1st embodiment is described.
Fig. 6 is the figure (4) for the analysis portion involved by the 1st embodiment is described.
Fig. 7 is the figure for the position alignment portion involved by the 1st embodiment is described.
Fig. 8 is the frame of the structure example representing the radiographic apparatus involved by the 1st embodiment Figure.
Fig. 9 is to represent to perform the image that the image processing system involved by the 1st embodiment is carried out The figure in the process portion of processing method.
Figure 10 is the place carried out for the diagnostic ultrasound equipment illustrated involved by the 1st embodiment The figure (1) of one example of reason.
Figure 11 is the place carried out for the diagnostic ultrasound equipment illustrated involved by the 1st embodiment The figure (2) of one example of reason.
Figure 12 is the place carried out for the radiographic apparatus illustrated involved by the 1st embodiment The figure (1) of one example of reason.
Figure 13 is the place carried out for the radiographic apparatus illustrated involved by the 1st embodiment The figure (2) of one example of reason.
Figure 14 is to represent the figure of an example of the view data of display in the 1st embodiment.
Figure 15 is the place carried out for the diagnostic ultrasound equipment illustrated involved by the 1st embodiment The flow chart of one example of reason.
Figure 16 is the place carried out for the radiographic apparatus illustrated involved by the 1st embodiment The flow chart of one example of reason.
Figure 17 is the figure for the 2nd embodiment is described.
Figure 18 is the place carried out for the radiographic apparatus illustrated involved by the 2nd embodiment The flow chart of one example of reason.
Detailed description of the invention
Hereinafter, referring to the drawings, the embodiment of image processing system is described in detail.
(the 1st embodiment)
First, the structure example for the image processing system involved by the 1st embodiment is said Bright.Fig. 1 is the figure of the structure example representing the image processing system involved by the 1st embodiment.
As it is shown in figure 1, the image processing system 1 involved by the 1st embodiment has ultrasound wave The diagnostic equipment 100, radiographic apparatus 200, X ray CT (Computed Tomography) Device 300, image archive apparatus 400 and image processing apparatus 500.Each exemplified by Fig. 1 Device is in such as by being arranged at LAN(Local Area Network in the hospital in hospital) 600, it is possible to the state being directly or indirectly in communication with each other.Such as, when medical imaging is examined Disconnected system introducing PACS(Picture Archiving and Communication System) Time, each device is according to DICOM(Digital Imaging and Communications in Medicine) standard, mutually sends and receives medical imaging etc..
Each device exemplified by Fig. 1 can receive the data of dicom standard by transmission, thus Read by this device or show the data received from other devices.It addition, it is if able to logical Cross this device to process the data received from other devices, then present embodiment can also Send and receive the data deferring to arbitrary standards.
Diagnostic ultrasound equipment 100 carries out the super of the two-dimensional scan of ultrasound wave by operator's adjustment The position of sonic probe, generates the ultrasound image data of arbitrary section.It addition, ultrasound wave The diagnostic equipment 100, by using machinery 4D to pop one's head in or 2D array probe, carries out ultrasound wave 3-D scanning, generates three-dimensional ultrasonic view data.It addition, radiographic apparatus 200 leads to Cross and enter when securing the position of C-arm of supporting X-ray tube and X-ray detector Row photography, generates two-dimensional x-ray images data.It addition, for involved by the 1st embodiment And diagnostic ultrasound equipment 100 and radiographic apparatus 200, describe in detail afterwards.
It addition, X ray CT device 300 has saturating to the X-ray tube of X-ray irradiation and detection The X-ray detector of the X-ray having crossed subject is supported on opposed position and can rotate Swivel mount.X ray CT device 300 is by while from X-ray tube X-ray irradiation while making rotation Pivoted frame rotates, thus covers collection in all directions and receive the X-ray passing through, absorbing, decay Data, rebuild X ray CT view data according to the data collected.X ray CT figure As data become the layer image in the X-ray tube surfaces of revolution (axial face) with X-ray detector. Here, in X-ray detector, as the x-ray detection device arranged in channel direction The body direction of principal axis that detecting element arranges along subject arranges multiple row.Such as, there is arrangement 16 row inspection Survey the X ray CT device 300 of X-ray detector of element row according to swivel mount rotation 1 time The data for projection collected, rebuilds along subject body axial multiple (such as 16) X Ray CT view data.
It addition, X ray CT device 300 is by making swivel mount rotate while making mounting tested The helical scanning that the top board of body moves, such as, can will cover 500 X-ray of heart entirety CT view data is rebuild as 3 D X-ray CT view data.Or, such as, have In the X ray CT device 300 of the X-ray detector arranging 320 row detecting element row, it is possible to Only by the conventional sweep carrying out making swivel mount to rotate 1 time, just rebuild that to cover heart overall 3 D X-ray CT view data.It addition, X ray CT device 300 can be by entering continuously Row helical scanning or conventional sweep, enter along time series 3 D X-ray CT view data Row photography.
In the 1st embodiment, use 3 D X-ray CT view data, carry out by ultrasound wave The ultrasound image data that the diagnostic equipment 100 photography obtains is taken the photograph with by radiographic apparatus 200 Position alignment between the X-ray image data that shadow obtains.To this, illustrating that the 1st implements Diagnostic ultrasound equipment 100 involved by mode and the overall knot of radiographic apparatus 200 After structure, it is described in detail.
Image archive apparatus 400 is the data base of keeping medical image data.Specifically, figure As storage appts 400 will be from diagnostic ultrasound equipment 100, radiographic apparatus 200 or X Ray CT apparatus 300 sends the medical image data come and is stored in the storage part of this device, goes forward side by side Row keeping.The medical image data that image archive apparatus 400 is taken care of such as with patient ID, inspection Look into the incidental informations such as ID, device ID, serial ID to take care of accordingly.
Doctor that image processing apparatus 500 e.g. works in hospital or laboratory technician are medical The work station reading to use in shadow of image or PC(Personal Computer) etc..At image The operator of reason device 500 can by carry out employing patient ID, check ID, device ID, The retrieval of serial ID etc., obtains required medical image data from image archive apparatus 400. Or, image processing apparatus 500 can also be from diagnostic ultrasound equipment 100, radiodiagnosis dress Put 200 or X ray CT device 300 directly receive view data.It addition, image procossing dress Put 500 in addition to showing medical imaging to read shadow, additionally it is possible to medical image data is entered The various image procossing of row.
Hereinafter, for diagnostic ultrasound equipment 100 and radiographic apparatus 200 phase cooperation The situation that ground performs with the image processing method involved by present embodiment illustrates.Wherein, The various places that diagnostic ultrasound equipment 100 described later and radiographic apparatus 200 are carried out Part or all of reason can also be by X ray CT device 300 or image processing apparatus 500 Perform.
It addition, image processing system 1 is not limited to be applicable to be imported with the situation of PACS.Example As, image processing system 1 can be applicable to be imported with the addition of medical image data equally The situation of the electronic medical record system that electronic health record is managed.Now, image archive apparatus 400 It is the data base of keeping electronic health record.It addition, such as image processing system 1 is equally applicable to lead Enter to have HIS(Hospital Information System), RIS(Radiology Information System) situation.
Then, for the structure example of the diagnostic ultrasound equipment 100 shown in Fig. 1, Fig. 2 is used Illustrate.Fig. 2 is the structure representing the diagnostic ultrasound equipment involved by the 1st embodiment The block diagram of example.Ultrasonic diagnosis as shown in Figure 1 as example, involved by the 1st embodiment Device 100 has: ultrasound probe 110, display 120, input unit 130, electrocardiogram are swept Retouch instrument 140, apparatus main body 150, position sensor 160 and emitter 161.
Ultrasound probe 110 carries out the transmission of ultrasound wave and receives.Such as, ultrasound probe 110 Having multiple piezoelectric vibrator, these multiple piezoelectric vibrators are according to from apparatus main body 150 institute described later The driving signal of transmission and reception unit 151 supply having is to produce ultrasound wave.It addition, ultrasound wave Probe 110 reception from the echo of subject P and is converted into the signal of telecommunication.It addition, ultrasound wave Probe 110 has the matching layer being arranged at piezoelectric vibrator and prevents ultrasound wave from piezoelectric vibrator backward The back lining materials etc. that side propagates.It addition, ultrasound probe 110 is freely torn open with apparatus main body 150 Link with unloading.
If subject P being sent ultrasound wave from ultrasound probe 110, then sent is ultrasonic Ripple is reflected successively by the discontinuity surface of the acoustic impedance in the in-vivo tissue of subject P, by ultrasound wave Multiple piezoelectric vibrators that probe 110 is had are received as reflection wave signal.The echo received The amplitude of signal depends on the difference of the acoustic impedance in the discontinuity surface of reflectance ultrasound ripple.It addition, institute Reflection during the surface reflection of the blood flow that moved of ultrasonic pulse sent or heart wall etc. Ripple signal due to Doppler effect, and can depend on moving body relative to ultrasound wave sending direction Velocity component, and accept frequency displacement.
Here, the ultrasound probe 110 involved by the 1st embodiment is to pass through ultrasound wave Two-dimensionally subject P is scanned, can dimensionally subject P be scanned simultaneously Ultrasound probe.Specifically, the ultrasound probe 110 involved by the 1st embodiment is logical Cross the multiple piezoelectric vibrators being configured to string, two-dimensionally subject P is scanned, leads to simultaneously Cross and make multiple piezoelectric vibrator swing with predetermined angular (pendulum angle), come dimensionally to subject The mechanical 4D probe that P is scanned.Or, the ultrasound probe involved by the 1st embodiment 110 is can be by being configured to rectangular by multiple piezoelectric vibrators, thus dimensionally to subject P Carry out the 2D array probe of ultrasonic scanning.It addition, 2D array probe can also be by assembling And send ultrasound wave, thus two-dimensionally subject P is scanned.
Input unit 130 has mouse, keyboard, button, panel-switch, touch instruction screen, foot Step on switch, trace ball, action bars etc., accept the operator from diagnostic ultrasound equipment 100 Various setting requirements, and apparatus main body 150 is transmitted the various setting requirements that accepted.
Display 120 display uses input unit for the operator of diagnostic ultrasound equipment 100 130 inputs are various sets the GUI(Graphical User Interface required), or The ultrasound image data etc. that display generates in apparatus main body 150.
As the signal of organism of subject P, ecg scanning instrument 140 obtains subject P's Electrocardiogram (ECG:Electrocardiogram).Ecg scanning instrument 140 is by acquired Electrocardiogram sends to apparatus main body 150.
Position sensor 160 and emitter 161 are the positions for obtaining ultrasound probe 110 The device of confidence breath.Such as, position sensor 160 is mounted to the magnetic of ultrasound probe 110 Sensor.It addition, such as, emitter 161 is configured in optional position, is to be with this device The device in formation magnetic field, centrally directed outside.
Position sensor 160 detects the three-dimensional magnetic field formed by emitter 161.Further, position Put the sensor 160 information according to the magnetic field detected, calculate with emitter 161 as initial point The position (coordinate and angle) of this device in space, and by the position that calculates to device Main body 150 sends.Here, position sensor 160 three-dimensional coordinate that this device is positioned at And angle is as the three dimensional local information of ultrasound probe 110, sends to apparatus main body 150.
It addition, present embodiment can also be applicable to by employ position sensor 160 and System beyond the position detecting system of emitter 161, obtains the position of ultrasound probe 110 The situation of information.Such as, present embodiment can also use gyro sensor or acceleration to pass Sensors etc., obtain the positional information of ultrasound probe 110.
Apparatus main body 150 is that the reflection wave signal received according to ultrasound probe 110 generates The device of ultrasound image data.Apparatus main body 150 shown in Fig. 1 is can be according to ultrasound wave The two-dimentional reflected waveform data that probe 110 receives is to generate the dress of two-dimensional ultrasonic view data Put.It addition, the apparatus main body 150 shown in Fig. 1 is can to receive according to ultrasound probe 110 To three-dimensional reflection wave datum generate the device of three-dimensional ultrasonic view data.
Apparatus main body 150 is as it is shown in figure 1, have transmission and reception unit 151, B-mode process portion 152, at doppler processing portion 153, image production part 154, image storage 155, image Reason portion 156, control portion 157, storage inside portion 158 and interface portion 159.
Transmission and reception unit 151 has pulse generator, sends delay portion, pulse generator etc., Signal is driven to ultrasound probe 110 supply.Pulse generator is with the rate frequency of regulation, instead Reproduce raw for forming the rate pulse sending ultrasound wave.It addition, send delay portion, pulse is produced Each rate pulse produced by raw device gives to be assembled the ultrasound wave produced by ultrasound probe 110 Fasciculation, and determine the time delay sending each piezoelectric vibrator needed for directivity.It addition, Pulse generator, with timing based on rate pulse, applies to drive signal to ultrasound probe 110 (driving pulse).That is, when sending delay portion by making the delay given for each rate pulse Between change, at random adjust the sending direction of ultrasound wave sent from piezoelectric vibrator face.
It addition, transmission and reception unit 151 is for the instruction according to control portion 157 described later, perform The scanning sequence of regulation, has the merit that can change transmission frequency moment, send driving voltage etc. Energy.Especially, the change of driving voltage is sent by the linear amplification that can switch its value moment The transtation mission circuit of type or TURP change the mechanism of multiple power subsystem and realize.
It addition, transmission and reception unit 151 has preamplifier, A/D(Analog/Digital) Transducer, reception delay portion and adder etc., anti-to received by ultrasound probe 110 Ejected wave signal carries out various process and generates reflected waveform data.Reflection wave signal is existed by preamplifier Each passage (channel) amplifies.Reflection wave signal after amplifying is carried out by A/D converter A/D changes.Receive delay portion and give the time delay determined needed for reception directivity.Adder Addition process is carried out to generate echo number to by the reflection wave signal after receiving the process of delay portion According to.By the addition process of adder, emphasize from the reception directivity pair with reflection wave signal The reflecting component in the direction answered, forms ultrasound wave send out according to reception directivity and transmission directivity Send the comprehensive wave beam of reception.
When subject P is carried out two-dimensional scan, transmission and reception unit 151 is from ultrasound probe 110 Send two-dimensional ultrasound wave beam.Further, transmission and reception unit 151 receives according to ultrasound probe 110 To two-dimentional reflection wave signal generate two dimension reflected waveform data.It addition, when subject P is entered During row 3-D scanning, transmission and reception unit 151 sends three-D ultrasonic wave beam from ultrasound probe 110. Further, transmission and reception unit 151 is according to the three-dimensional reflection ripple letter received by ultrasound probe 110 Number generate three-dimensional reflection wave datum.
It addition, the form from the output signal of transmission and reception unit 151 can select to be known as RF(Radio Frequency) at the signal comprising phase information of signal or envelope detection The various forms such as the situation of the amplitude information after reason.
B pattern process portion 152 receives reflected waveform data from transmission and reception unit 151, carries out logarithm Amplification, envelope detection process etc., generate the data (B that signal intensity is showed by the light and shade of brightness Pattern data).
Doppler processing portion 153 is according to the reflected waveform data pair received from transmission and reception unit 151 Velocity information carries out frequency analysis, extracts blood flow based on Doppler effect, tissue or contrast agent Echo component, generate extract for multiple spot speed, variance, the number of idempotent mobile unit information According to (doppler data).
It addition, the B pattern process portion 152 involved by the 1st embodiment and doppler processing Portion 153 can for two dimension reflected waveform data and three-dimensional reflection wave datum both sides at Reason.That is, B pattern process portion 152 generates two dimension B pattern number according to two dimension reflected waveform data According to, generate three-dimensional B pattern data according to three-dimensional reflection wave datum.It addition, doppler processing Portion 153 generates two-dimensional Doppler data, according to three-dimensional reflection ripple according to two dimension reflected waveform data Data generate three-dimensional Doppler data.
Image production part 154 is according to by B pattern process portion 152 and doppler processing portion 153 The data generated generate ultrasound image data.That is, image production part 154 is schemed according to by B The two-dimentional B pattern data that case process portion 152 generates generate and are represented reflection wave strength by brightness Two dimension B pattern view data.It addition, image production part 154 is according to by doppler processing portion 153 The two-dimensional Doppler data generated generate the two-dimensional Doppler picture number representing mobile unit information According to.Two-dimensional Doppler view data is velocity image, variance image, power image or is combined with These image.
Here, image production part 154 is typically by the scanning-line signal of ultrasonic scanning Row conversion (scan conversion) become the scanning-line signal row of the representative video formats such as TV, raw Become the ultrasound image data of display.Specifically, image production part 154 is according to ultrasound wave The scan mode of the ultrasound wave of probe 110 carries out Coordinate Conversion, thus generates the super of display Sound wave view data.It addition, image production part 154 is in addition to scan conversion, as various Image procossing, such as, use the multiple picture frames after scan conversion, carries out regenerating brightness and puts down The image procossing (smoothing techniques) of average image or use differential filter in image Image procossing (edge enhancement process) etc..It addition, image production part 154 is to ultrasonography Data, synthesize the Word message of various parameter, scale, body mark etc..
That is, B pattern data and doppler data is scan conversion ultrasonography before treatment Data, the data that image production part 154 is generated are the super of the display after scan conversion processes Sound wave view data.It addition, B pattern data and doppler data are also known as initial data (Raw Data).
It addition, image production part 154 is by the three-dimensional B generated by B pattern process portion 152 Pattern data carries out Coordinate Conversion, generates three-dimensional B pattern view data.It addition, image is raw One-tenth portion 154 carries out coordinate by the three-dimensional Doppler data being generated doppler processing portion 153 Conversion, generates three-dimensional Doppler view data.That is, image production part 154 will " three-dimensional B Pictorial image data or three-dimensional Doppler view data " conduct " three-dimensional ultrasonic view data " Generate.
It addition, image production part 154 is in order to generate for by three-dimensional ultrasonic view data (body Data) it is shown in the various two-dimensional image datas of display 120, volume data is carried out at drafting Reason.The drawing modification carried out as image production part 154, exist the profile Reconstruction method that carries out (MPR: Multi Planar Reconstruction) according to volume data generate MPR view data place Reason.It addition, the drawing modification carried out as image production part 154, exist and volume data is carried out The process of " Curved MPR " or volume data is carried out " Maximum Intensity Projection " process.It addition, the drawing modification carried out as image production part 154, There is the volume drawing (VR:Volume of the two-dimensional image data generating reflection three-dimensional information Rendering) process.
Image storage 155 is the picture number of the display that storage image production part 154 is generated According to memorizer.It addition, image storage 155 can also store B pattern process portion 152 or The data that doppler processing portion 153 is generated.The B pattern number that image storage 155 is stored According to or doppler data such as diagnosis after can be recalled by operator, via image production part 154 ultrasound image data becoming display.It addition, image production part 154 is by ultrasound wave View data and time of ultrasonic scanning of carrying out to generate this ultrasound image data with The electrocardiogram foundation sent from ecg scanning instrument 140 is stored in image storage 155 accordingly. Analysis portion 156a described later or control portion 157 can be by referring to being stored in image storage 155 Data, thus obtain carry out to generate ultrasound image data ultrasonic scanning time Heart phase.
Storage inside portion 158 storage is used for carrying out ultrasound wave and sends reception, image procossing and show Show the control program of process, diagnostic message (such as, the suggestion etc. of patient ID, doctor), examine The disconnected various data such as agreement or various body marks.It addition, storage inside portion 158 is as required, It is additionally operable to the keeping etc. of the view data that image storage 155 is stored.It addition, storage inside The data that portion 158 is stored can be via interface portion 159 described later, to outside device transmission. It addition, the data that external device (ED) is stored can also be via interface portion 159 described later, internally Storage part 158 transmits.It addition, the external device (ED) e.g. radiographic apparatus shown in Fig. 1 200, X ray CT device 300, image archive apparatus 400 or image processing apparatus 500 etc..
Image processing part 156 is in order to carry out computer-aided diagnosis (Computer-Aided Diagnosis:CAD) apparatus main body 150 it is arranged at.Image processing part 156 obtains preservation In the ultrasound image data of image storage 155, carry out image analysis processing.Further, figure As analysis result is stored in image storage 155 or storage inside portion 158 by process portion 156.
Image processing part 156 is as it is shown in figure 1, have analysis portion 156a and position alignment portion 156b. Analysis portion 156a to generate by subject P is carried out three-dimensional ultrasonic scanning along the time The three-dimensional ultrasonic image data set of sequence is analyzed, and generates and the local specified in tissue The three dimensional analysis view data that motion is relevant.
Here, regulation tissue is heart, analysis portion 156a generates the motion in each region with heart wall Relevant information.Further, analysis portion 156a generate ultrasound image data endomyocardial, Or the analysis view data after heart wall motion information is mapped between heart muscle inner membrance and adventitia.1st Analysis portion 156a involved by embodiment uses three-dimensional ultrasonic image data set, generates three-dimensional The time series data of heart wall motion information.
Hereinafter, the analyzing and processing carried out for analysis portion 156a involved by the 1st embodiment, Fig. 3～Fig. 6 is used to illustrate.Fig. 3～Fig. 6 is for illustrating involved by the 1st embodiment The figure of analysis portion.
First, use can the ultrasound probe 110 of 3-D scanning, operator such as passes through the heart Point path period more than 1 heart beating, system is felt concerned about on the left side of the heart of subject P and carries out three Dimension scanning.Thus, image production part 154 generates the time of the period more than 1 heart beating Multiple three-dimensional ultrasonic view data of sequence, are stored in image storage 155.Image stores Multiple three-dimensional ultrasonic view data that device 155 is preserved are by by including at least left ventricle The three-dimensional ultrasonic image that heart period more than 1 heart beating carries out ultrasonic scanning and generates Data set.It addition, above-mentioned three-dimensional ultrasonic image data set is three-dimensional B pattern view data Group.
Further, as analysis portion 156a example as shown in Figure 3, it is taken along more than 1 heart beating Seasonal effect in time series multiple three-dimensional ultrasonic view data.In each three-dimensional ultrasonic view data, Include the left ventricle of subject P.
Further, analysis portion 156a, according to three-dimensional ultrasonic image data set, calculates in left ventricle The time series data of heart wall motion information.Specifically, analysis portion 156a uses by comprising The result that the process of the pattern match between view data is followed the trail of above-mentioned tracking point and obtained, is carried out The calculating of heart wall motion information processes.More specifically, analysis portion 156a uses for by three-dimensional The three-dimensional dynamic images data that echocardiography obtains carry out three-dimensional speckle tracking (3D Speckle Tracking, hereinafter referred to as " 3DT ") result, calculate heart wall motion information. Speckle tracking method be process with pattern match together with, such as by and with optical flow method or various time Space interpolation processing, thus the method that presumption is movable accurately.It addition, in speckle tracking method, Also comprise and do not carry out pattern match process, and the method for presumption activity.
Such as, input unit 130 accepts the 1st of three-dimensional ultrasonic image data set at operator The display requirement of frame (the 1st volume).The control portion 157 transferring display requirement deposits from image Reservoir 155 reads the three-dimensional ultrasonic view data of the 1st frame, is shown in display 120.Example As, the section that control portion 157 makes image production part 154 generate in multiple directions cuts off the 1st frame Three-dimensional ultrasonic view data and multiple MPR view data of obtaining, and be shown in display 120.Such as, display 120 as shown in Figure 4, shows multiple MPR view data.
In shown in Fig. 4 a example, display 120 is at the MPR in region A display A face View data.It addition, in shown in Fig. 4 a example, display 120 shows at region B Show the MPR view data in B face.It addition, in shown in Fig. 4 a example, display 120 MPR view data in the C face of the near C3 grade of region C3 display distance apex.It addition, In shown in Fig. 4 a example, display 120 is near at region C3 display distance heart base portion The MPR view data in the C face of C7 grade.It addition, in shown in Fig. 4 a example, aobvious Show that device 120 shows the C face being positioned at apex with the C5 grade of the centre of heart base portion at region C5 MPR view data.In shown in Fig. 4 a example, in the viewing area in left side, From upper beginning successively configuring area C3, region C5, region C7, at region C3 and region C5 Right side configuring area A, at the right side configuring area B of region A.
It addition, in shown in Fig. 4 a example, display 120 is in the district of lower right side Territory, the volume rendered images of the three-dimensional ultrasonic view data of display the 1st frame and electrocardiogram.
Further, operator, with reference to the multiple MPR view data shown by display 120, sets Multiple tracking points carrying out 3DT.Example is given one example, operator in each MPR view data, Traced for left ventricular endocardium or the position of heart muscle adventitia, it is intended that inner membrance profile and epicardium contours.Point Analysis portion 156a constitutes three-dimensional inner membrance profile according to specified inner membrance profile and epicardium contours And three-dimensional epicardium contours.Further, as analysis portion 156a example as shown in Figure 5, will constitute The each point of the three-dimensional inner membrance profile of the 1st frame is set as tracking point.Although it addition, do not illustrate, But each point constituting the three-dimensional epicardium contours of the 1st frame is set as tracking point by analysis portion 156a.And And, analysis portion 156a, respectively to the multiple tracking points set with the 1st frame, sets template data. Template data is made up of the multiple voxels centered by tracking point.
Further, analysis portion 156a by exploring speckle pattern with template data 2 interframe Consistent region, thus follow the trail of which position template data moves at next frame.Thus, divide Analysis portion 156a is as it is shown in figure 5, who of n-th frame each tracking point of tracking the 1st frame move to Put.It addition, the 1st can also be detected by analysis portion 156a for setting the grid of tracking point Endocardial surface or the epicardial surface of the left ventricle that frame is comprised set.
Analysis portion 156a is by overall for left ventricle (such as, the endocardium of left ventricle and left ventricle Visceral pericardium) as object, carry out the 3DT for three-dimensional ultrasonic image data set.Further, Analysis portion 156a is according to the result of the 3DT for three-dimensional ultrasonic image data set, in each tracking Point, generates the time series data of heart wall motion information.Such as, analysis portion 156a is according to intracardiac Film and the result of epicardial 3DT, calculate strain (Strain) as heart wall motion information. Analysis portion 156a calculates the strain (LS) in major axis (Longitudinal) direction, circumference (Circumferential) strain (CS) in direction or answering of wall thickness (Radial) direction Become (RS).
Or, such as, analysis portion 156a, according to the result of the 3DT of inner membrance, calculates left room intracardiac The area change rate (Area Change ratio:AC) of face is as heart wall motion information.Or Person, such as analysis portion 156a can also come according to endocardium or the result of epicardial 3DT Calculate displacement (Displacement).When using displacement as heart wall motion information, analyze Portion 156a can calculate the displacement (LD) of long axis direction or the displacement (RD) in wall thickness direction.Or Person, analysis portion 156a can also calculate relative to the tracking at benchmark phase (such as, R ripple) Displacement (the Absolute of the position of point, phase beyond reference phase tracking point Displacement:AD).It addition, analysis portion 156a is in order to capture the asynchronous of cardiomotility Property, it is also possible to calculate and Strain value become the analysis that certain above time maps tie Really or to Strain value reach the analysis result that the time of maximum maps.
Here, analysis portion 156a can generate the time sequence of heart wall motion information to each tracking point Column data, it is also possible to the time series data to the Area generation heart wall motion information of each local. Such as, analysis portion 156a uses ultrasoundcardiogram association of the U.S. or American Heart Association to be recommended 16 or 17 cut zone divided, calculate the heart wall motion information of local.Such as, as U.S. The division that ultrasoundcardiogram association of state etc. is recommended, it is possible to enumerate in antetheca every (ant-sept.), Antetheca (ant.), sidewall (lat.), rear wall (post.), lower wall (inf.), in every (sept.) etc..
Further, such as analysis portion 156a is as shown in Figure 6, generates the heart that will be obtained by each tracking point The value of wall movable information is converted into colour, and be mapped to the iso-surface patch image of three-dimensional inner membrance profile Three dimensional analysis view data.Operator can pass through moving view point position, thus passes through display 120 observe the three dimensional analysis view data exemplified by Fig. 6 from all directions.Or, such as, Analysis portion 156a generates and the value of the heart wall motion information obtained by each tracking point is converted into colour, And it is mapped to the three dimensional analysis view data of the Polar-map of 16 divisions.
Return to Fig. 2, position alignment portion 156b and carry out ultrasound image data and other kinds of Position alignment between three-dimensional medical image data processes.The so-called medical figure of other kinds of three-dimensional The 3 D X-ray CT view data e.g. received from X ray CT device 300 as data. Or, so-called other kinds of three-dimensional medical image data refers to from the magnetic resonance that Fig. 1 is not shown The three-dimensional MRI that imaging (MRI:Magnetic Resonance Imaging) device receives View data.Diagnostic ultrasound equipment 100 involved by 1st embodiment can pass through position Sensor 160 and the process of position alignment portion 156b, make image production part 154 generate with for The section of the two-dimensional ultrasonic scanning generating two-dimensional ultrasonic view data and carry out is the most same The medical image data of section, and it is shown in display 120.
Such as, operator is at the ultrasoundcardiogram using ultrasound probe 110 to carry out subject P Before inspection, the 3 D X-ray CT image that carrying out photographs to the heart of subject P obtains The transmission requirement of data.It addition, operator via input unit 130 MPR is processed transversal The position in face is adjusted, so that being penetrated by the two-dimentional X of the check point depicting subject P Line CT view data is shown in display 120.
Further, by the control of position alignment portion 156b, image production part 154 generates by operating Cross section (hereinafter referred to as " initial profile ") after person's regulation has cut off 3 D X-ray CT The two-dimensional x-ray CT view data of view data, display 120 shows image production part 154 The two-dimensional x-ray CT view data generated.Operator operate ultrasound probe 110 carry out with The ultrasonic scanning of the X ray CT view data same profile shown by display 120.Further, When the two-dimensional x-ray CT view data being judged as shown by display 120 and two-dimensional ultrasonic figure As data be substantially same profile time, such as operator specifies correspondence in the view data of both sides 3 points.Or, operator such as specify in the view data of both sides correspondence 1 with On point and axle (line).Further, operator presses the confirming button of input unit 130.Position Aligned portions 156b by press moment of confirming button from position sensor 160 obtain ultrasonic The three dimensional local information of ripple probe 110 is set as initial position message.Or, position alignment portion 156b, by establishing point or the line of corresponding relation, carries out the seat of two-dimensional ultrasonic view data The position alignment of the coordinate system of mark system and 3 D X-ray CT view data.Fig. 7 is for illustrating The figure in the position alignment portion involved by the 1st embodiment.
Afterwards, position alignment portion 156b is constituted from by position sensor 160 and emitter 161 Position detecting system, obtain two-dimensional ultrasonic view data B shown in Fig. 7 generate time The three dimensional local information of ultrasound probe 110.Further, position alignment portion 156b is by obtaining institute The three dimensional local information obtained and the mobile message of initial position message according to acquired movement The position of information change initial profile, resets the cross section of MPR.Further, pass through The control of position alignment portion 156b, image production part 154 is by position alignment portion 156b again The cross section set, generates two dimension according to 3 D X-ray CT view data A shown in Fig. 7 X ray CT view data C.Further, by the control of position alignment portion 156b, display 120 as it is shown in fig. 7, show two-dimensional x-ray CT view data C and two-dimensional ultrasonic figure side by side As data B.It addition, in above-mentioned, carry out position alignment for using position sensor 160 Situation be illustrated.But, three-dimensional ultrasonic view data and 3 D X-ray CT image The position alignment of data (or, three-dimensional MRI image data) have collected three-dimensional ultrasonic figure As after data, if setting more than 3 common characteristic points in the view data of both sides, Even if then non-use position sensor 160 can be carried out too.Such as, if showing both sides MPR view data, set common characteristic point independently, when set more than 3 when Make image synchronization, then can be carried out by interfaces such as mouses and use position sensor 160 phase Show while Tong.
Shown function by this, operator such as can observe ultrasonography simultaneously and cut open simultaneously The X ray CT image that face is roughly the same with this ultrasonography.It addition, can be entered by use The ultrasound probe 110 of row 3-D scanning carries out two-dimensional scan, obtains initial position message in advance With establish point or the positional information of line of corresponding relation, thus position alignment portion 156b can be 3 D X-ray CT view data is identified big with the 3D region dimensionally carrying out ultrasonic scanning Cause identical 3D region.It addition, position alignment portion 156b can carry out constituting three-dimensional ultrasonic The position pair of each voxel of each voxel of view data and composition 3 D X-ray CT view data Accurate.
That is, position alignment portion 156b can carry out three-dimensional ultrasonic view data and 3 D X-ray The position alignment of CT view data or three-dimensional ultrasonic view data and three-dimensional MRI image data Position alignment.It addition, position alignment portion 156b can use three-dimensional ultrasonic view data with The position alignment information of 3 D X-ray CT view data, carries out three dimensional analysis view data and three The position alignment of dimension X ray CT view data, similarly, it is possible to use three-dimensional ultrasonic image The position alignment information of data and three-dimensional MRI image data, carry out three dimensional analysis view data with The position alignment of three-dimensional MRI image data.It addition, when 3 D X-ray CT view data or three Dimension MRI image data be radiography photography obtain three-dimensional image data time, it is possible to carry out from The three-dimensional Contrast Area numeric field data being partitioned in three-dimensional image data and three dimensional analysis view data Position alignment.
Returning to Fig. 2, the process that control portion 157 controls diagnostic ultrasound equipment 100 is overall. Specifically, control portion 157 is according to the various settings inputted via input unit 130 by operator The various control programs required or read in from storage inside portion 158 and various data, control to send out Send acceptance division 151, B pattern process portion 152, doppler processing portion 153, image production part 154 And the process of analysis portion 156a.It addition, control portion 157 is controlled, so that display The display ultrasonogram that 120 display image memory 155 or storage inside portion 158 are stored As data.It addition, control portion 157 is controlled, so that display 120 shows analysis portion The result of 156a.
It addition, control portion 157 by result of analysis portion 156a etc. via interface portion described later 159 export to external device (ED).The external device (ED) e.g. radiographic apparatus 200 shown in Fig. 1, X ray CT device 300, image archive apparatus 400 or image processing apparatus 500 etc..1st Control portion 157 involved by embodiment is as the while of for carrying out the output process exporting data Control the process portion of the data form of output data, there is output unit 157a shown in Fig. 1.Separately Outward, the process carried out for output unit 157a, describe in detail afterwards.
Interface portion 159 is for LAN600, radiographic apparatus in input unit 130, hospital 200, X ray CT device 300, image archive apparatus 400 and image processing apparatus 500 Interface.Such as, input unit 130 is accepted various set informations from operator and Various instructions, by interface portion 159, transmit to control portion 157.It addition, such as output unit 157a The output data exported pass through interface portion 159, via LAN600 in hospital to radiodiagnosis Device 200 sends.It addition, such as X ray CT device 300 or image archive apparatus 400 The data such as the three-dimensional medical image data sent, via interface portion 159, are stored in storage inside Portion 158.
Then, for the structure example of the radiographic apparatus 200 shown in Fig. 1, Fig. 8 is used Illustrate.Fig. 8 is the structure representing the radiographic apparatus involved by the 1st embodiment The block diagram of example.Radiodiagnosis as shown in Figure 8 as example, involved by the 1st embodiment Device 200 possesses X-ray high voltage device 211, X-ray tube 212, x-ray diAN_SNhragm device 213, top board 214, C-arm 215, X-ray detector 216.It addition, the 1st embodiment Involved radiographic apparatus 200 possesses C-arm rotation/travel mechanism 217, top board moves Motivation structure 218, C-arm/top panel mechanism control portion 219, diaphragm control portion 220, system control Portion 221, input unit 222 and display part 223.It addition, the X involved by the 1st embodiment Ray diagnostic device 200 possess image data generating section 224, image data storing section 225 with And image processing part 226.
X-ray high voltage device 211, according to the control of systems control division 221, produces high voltage, And supply produced high voltage to X-ray tube 212.X-ray tube 212 uses from X-ray The high voltage of high voltage device 211 supply, produces X-ray.
X-ray diAN_SNhragm device 213 according to the control in diaphragm control portion 220 by X-ray tube 212 Produced X-ray is converged to optionally irradiate the Region Of Interest of subject P.Such as, X Ray aperture device 213 has 4 blades of diaphragm that can slide.X-ray diAN_SNhragm device 213 By making these blades of diaphragm slide according to the control in diaphragm control portion 220, thus assemble X and penetrate X-ray produced by spool 212 is irradiated to subject P.Top board 214 is mounting subject P Bed, be configured on not shown examination platform.
X-ray detector 216 detection has passed through the X-ray of subject P.Such as, X-ray inspection Survey device 216 and there is the detecting element of rectangular arrangement.Each detecting element will transmit through subject P X-ray be converted into the signal of telecommunication and accumulate, by the signal of telecommunication accumulated to image data generating section 224 send.
C-arm 215 keeps X-ray tube 212, x-ray diAN_SNhragm device 213 and X-ray inspection Survey device 216.X-ray tube 212 and x-ray diAN_SNhragm device 213 and X-ray detector 216 It is configured to by C-arm 215 opposed across subject P.
C-arm rotation/travel mechanism 217 is for making C-arm 215 rotate and the machine of movement Structure, top board travel mechanism 218 is the mechanism for making top board 214 move.C-arm/top board machine Structure control portion 219, by the control according to systems control division 221, controls C-arm and rotates/move Mechanism 217 and top board travel mechanism 218, thus to the rotation of C-arm 215 or movement, Top board 214 move into Row sum-equal matrix.Diaphragm control portion 220 is by according to systems control division 221 Control, the aperture of the blade of diaphragm that x-ray diAN_SNhragm device 213 is had is adjusted, Thus control the range of exposures to the X-ray that subject P irradiates.
Image data generating section 224 uses to be changed out from X-ray by X-ray detector 216 The signal of telecommunication generate X-ray image data, and the X-ray image data generated is stored in Image data storing section 225.Such as, image data generating section 224 is to by X-ray detector 216 signals of telecommunication received, carry out current/voltage-converted, A(Analog)/D(Digital) Conversion or parallel/series conversion, generate X-ray image data.
Image data storing section 225 stores the view data generated by image data generating section 224. The view data that image data storing section 225 is stored by image processing part 226 carries out various figure As processing.Describe in detail for after the image procossing that image processing part 226 is carried out.
Input unit 222 is at the operators such as the doctor operating radiographic apparatus 200 or technician Accept various instruction.Such as, input unit 222 have mouse, keyboard, button, trace ball, Action bars etc..Input unit 222 by the instruction that receives at operator to systems control division 221 Transmit.
Display part 223 display is for accepting the GUI(Graphical User of the instruction of operator Or the display view data etc. that stored of image data storing section 225 Interface).Such as, Display part 223 has display.It addition, display part 223 can also have multiple display.
Systems control division 221 controls the action of radiographic apparatus 200 entirety.Such as, it is System control portion 221 is by indicating control X-ray according to the operator come from input unit 222 transmission High voltage device 211, and adjust the voltage to X-ray tube 212 supply, thus control quilt Amount of x-ray or the ON/OFF(of x-ray bombardment that corpse or other object for laboratory examination and chemical testing P irradiates open or close). It addition, such as, systems control division 221 controls C-arm/top panel mechanism according to the instruction of operator Control portion 219, to the rotation of C-arm 215 or movement, top board 214 move into Row sum-equal matrix. It addition, such as, systems control division 221 controls diaphragm control portion by the instruction according to operator 220, the aperture of the blade of diaphragm that x-ray diAN_SNhragm device 213 is had is adjusted, thus Control the range of exposures to the X-ray that subject P irradiates.
It addition, systems control division 221 is according to the instruction of operator, control based on view data raw The view data generation in one-tenth portion 224 processes or image procossing etc. based on image processing part 226. It addition, systems control division 221 is controlled, so that the display display of display part 223 is used In the view data etc. that the GUI or image data storing section 225 that accept operator's instruction are stored.
Here, systems control division 221 receives from diagnostic ultrasound equipment 100 to use Output data carry out various process, as it is shown on figure 3, have obtaining section 221a.Obtaining section 221a It is by the process portion of position alignment process described later etc..That is, if image processing system 1 will Above-mentioned position alignment portion 156b as the 1st position alignment portion, then has as the 2nd position pair Obtaining section 221a in quasi-portion.It addition, describe in detail after the process carried out for obtaining section 221a.
Interface portion 227 is for LAN600, radiographic apparatus 200, X-ray in hospital CT device 300, image archive apparatus 400 and the interface of image processing apparatus 500.Such as, It is defeated that interface portion 227 involved by present embodiment receives that diagnostic ultrasound equipment 100 exported Go out data, and the obtaining section output data received being had to systems control division 221 221a transmits.
Above, the overall structure for the image processing system 1 involved by the 1st embodiment is entered Row explanation.In the structure shown here, in the image processing system 1 involved by the 1st embodiment, By using the ultrasound investigation of diagnostic ultrasound equipment 100, determine the position needing treatment. Specifically, at cardiac resynchronization therapy method (CRT:Cardiac Resynchronization Therapy), in, the asynchronous position of the electrode of indwelling cardiac pacemaker is according to analysis portion 156a The three dimensional analysis view data generated determines.Here, in a crt, doctor's reference The radioscopic image obtained by radiographic apparatus 200 perspective photography, is stayed electrode Put at the vein nearest apart from asynchronous position.But, under radioscopy, it is difficult to differentiate The inside and outside face of heart wall, accordingly, it is difficult to carry out X-ray image data and analyze view data Position alignment, is i.e. difficult to the position alignment of X-ray image data and ultrasound image data.
Therefore, in the 1st embodiment, pass through ultrasound wave to differentiate under radioscopy The position that diagnosis determines, each portion shown in Fig. 9 carries out following process.Fig. 9 is to represent execution The process portion of the image processing method that the image processing system involved by the 1st embodiment is carried out Figure.
In the 1st embodiment, the 1st first had as diagnostic ultrasound equipment 100 The position alignment portion 156b in position alignment portion carries out what the photography of the regulation tissue to subject P obtained 1st three-dimensional medical image data and the position alignment of the 2nd three-dimensional medical image data.Here, The three-dimensional medical image data in above-mentioned the 1st is three can be analyzed the motion of regulation tissue Dimension medical image data.Specifically, the 1st three-dimensional medical image data is three-dimensional ultrasonic figure As data.It addition, the 2nd above-mentioned three-dimensional medical image data is according to X-ray image data The three-dimensional medical image data that particular organization's mappedization that can differentiate obtains.That is, as The position alignment portion 156b in 1 position alignment portion carries out photographing the regulation tissue of subject P The three-dimensional ultrasonic view data obtained with the regulation tissue of subject P carried out photography obtain , can according to X-ray image data differentiate particular organization's mappedization obtain and three The position alignment of the 2nd three-dimensional medical image data that dimension ultrasound image data is different.Here, So-called regulation tissue refers to heart.It addition, specifically, the three-dimensional medical imaging in above-mentioned the 2nd Data are 3 D X-ray CT view data or three-dimensional MRI image data.Above-mentioned the 2nd Three-dimensional medical image data is three-dimensional image data as an example, is to coronary artery The three-dimensional that (coronary artery) or Coronary vein (coronary vein) radiography obtain X ray CT view data or the three-dimensional MRI image that coronary artery or Coronary venography are obtained Data.Above-mentioned particular organization is the tissue being capable of identify that according to X-ray image data.Specifically For, above-mentioned particular organization is to photograph according to the heart as regulation tissue is carried out radiography To the tissue that is capable of identify that of x-ray imaging view data.Such as, above-mentioned particular organization is Coronary artery or Coronary vein.It addition, the 2nd three-dimensional that particular organization's mappedization obtains is medical View data in addition to three-dimensional image data, such as, can also be to be photographed by non-radiography The three-dimensional MRI image data that blood flow labelling is obtained.Hereinafter, for the 2nd three-dimensional medical imaging Data are that the situation of three-dimensional image data illustrates.
Here, owing to dye shadow degree coronarius is higher than the dye shadow degree of Coronary vein, therefore, three Dimension image data is preferably used the 3 D X-ray CT picture number obtaining coronarography According to or three-dimensional MRI image data that coronarography is obtained.Hereinafter, for will be as spy The 3 D X-ray CT view data that the coronarography of fixed tissue obtains is three-dimensional as the 2nd The situation of the three-dimensional image data of medical image data illustrates.
Further, output unit 157a that diagnostic ultrasound equipment 100 is had will be to the 1st three-dimensional doctor With the three-dimensional medical image data (three of view data (three-dimensional ultrasonic view data) and the 2nd Dimension image data) addition of the data of position alignment information and export as output data. Or, output unit 157a will be to the 1st three-dimensional medical image data (three-dimensional ultrasonic view data) Carry out position alignment with the 2nd three-dimensional medical image data (three-dimensional image data) and synthesize Generated data as output data export.
Further, the acquirement as the 2nd position alignment portion that radiographic apparatus 200 is had Portion 221a receives output data, carries out the 2nd three-dimensional medical image data and the rule to subject P The multiple radioscopic images corresponding with photography direction that fixed tissue obtains from the photography of multiple photography directions The position alignment of data.Or, obtaining section 221a as the 2nd position alignment portion carries out the 2nd Three-dimensional medical image data obtains with photographing the regulation tissue of subject P from 1 photography direction The position alignment of 1 corresponding with photography direction X-ray image data.Further, X-ray The display part 223 that the diagnostic equipment 200 is had is according to the position pair as the 1st position alignment portion The position alignment result of quasi-portion 156b and obtaining section 221a as the 2nd position alignment portion Position alignment result, show the 1st three-dimensional medical image data position alignment in regulation tissue The view data of X-ray image data.
Specifically, obtaining section 221a is according to the 2nd three-dimensional medical image data and multiple X-ray The position alignment result of view data, obtains the 3-D photography space Zhong Te of X-ray image data The three dimensional local information of fixed tissue.Or, obtaining section 221a is according to the 2nd three-dimensional medical imaging number According to the position alignment result with 1 X-ray image data, obtain the three of X-ray image data The three dimensional local information of particular organization in dimension photographing space.
More specifically, by the control of obtaining section 221a, when by the 2nd three-dimensional medical imaging number According to when being configured at the 3-D photography space of radiographic apparatus 200, display part 223 shows spy Fixed tissue is projected to the projection image after multiple X-ray image data.Further, obtaining section 221a According to reference to display part 223 operator in above-mentioned multiple X-ray image data with spy Surely organize corresponding position that the position of projection image is set up corresponding operation, obtain three-dimensional position Information.Or, by the control of obtaining section 221a, when the 2nd three-dimensional medical image data is joined When being placed in the 3-D photography space of radiographic apparatus 200, display part 223 shows specific group Knit the projection image after being projected to 1 X-ray image data.Further, obtaining section 221a according to With reference to the operator of display part 223 in above-mentioned 1 X-ray image data with particular organization Corresponding operation is set up in the position of projection image by corresponding position, obtains three dimensional local information.
That is, the position alignment that obtaining section 221a is carried out processes by by " two-dimensional x-ray images The two-dimentional particular organization that data are depicted " and " the 2nd three-dimensional medical image data is described It is special that the three-dimensional particular organization gone out projects the two dimension obtained to the photography direction of this X-ray image data Fixed tissue " carry out 3 correspondences established above.Accordingly, as the 2nd position alignment portion Obtaining section 221a can use 1 X-ray image data obtained from 1 photography direction photography, Carry out position alignment process.
Further, display part 223 shows the three dimensional local information according to particular organization and the 1st three Dimension medical image data and the relative position relation of the 2nd three-dimensional medical image data, by the 1st three Tie up medical image data or generate by the 1st three-dimensional medical image data is analyzed Analyze the image data location view data in alignment with the X-ray image data of regulation tissue.
Here, obtaining section 221a as the 2nd position alignment portion carries out " the 1 of position alignment process Individual or multiple X-ray image data " be " particular organization is carried out radiography photograph obtain 1 Individual or multiple x-ray imaging view data ".Or, as taking of the 2nd position alignment portion Portion 221a to carry out " 1 or multiple X-ray image data " of position alignment process be " right The particular organization being inserted into utensil carries out photograph 1 obtained or multiple radioscopic image number According to ".Above-mentioned utensil e.g. inserts the seal wire (guide of coronary artery or Coronary vein Wire).Owing to seal wire is X-ray impermeability, therefore when inserting seal wire In the X-ray image data that photography obtains, contrast agent need not be injected and the most clearly depict and be preced with Shape tremulous pulse or region corresponding to Coronary vein.
Hereinafter, for obtaining section 221a as " multiple X-ray image data " use " many Multiple x-ray imaging view data that the photography of individual photography direction radiography obtains ", carry out position pair Accurate situation about processing illustrates.Wherein, the content of following description can also be applicable to " multiple X-ray image data " it is " the multiple X obtained in the photography of multiple photography directions when inserting seal wire Radiographic image data " situation.It addition, the content of following description can also be suitable as " 1 Individual X-ray image data " " 1 X obtained 1 photography direction radiography photography penetrates in use Line image data " situation or " obtain in the photography of 1 photography direction when inserting seal wire 1 X-ray image data " situation.
Such as, obtaining section 221a receives output data, carry out three-dimensional image data with will be by Multiple x-ray imaging view data that the heart of corpse or other object for laboratory examination and chemical testing P obtains from multiple directions photography are respective Position alignment, the particular organization in the 3-D photography space of acquirement x-ray imaging view data Three dimensional local information.
Further, such as, display part 223 is according to the three dimensional local information of particular organization and three-dimensional Ultrasound image data and the relative position relation of three-dimensional image data, show above-mentioned point Analysis view data (three dimensional analysis view data) position alignment is in the radioscopic image of regulation tissue View data after data.
Hereinafter, an example of the process carried out for each portion shown in Fig. 9 illustrates.Figure 10 and Figure 11 is for illustrating that the diagnostic ultrasound equipment involved by the 1st embodiment is carried out The figure of an example of process.
As it has been described above, position alignment portion 156b can use by position sensor 160 and launch The position detecting system that device 161 is constituted, carries out the three-dimensional being partitioned into from three-dimensional image data Contrast Area numeric field data and the position alignment of three dimensional analysis view data.In the present embodiment, make Being an example, position alignment portion 156b is three generated according to three-dimensional ultrasonic image data set Dimension is analyzed in image data set, by ED three dimensional analysis view data (with reference to Fig. 6) Object as position alignment.
It addition, position alignment portion 156b is for 3 D X-ray CT view data (reference Figure 10 Left figure), use for the threshold process of voxel value or region diastole method, will be extracted crown The three-dimensional Contrast Area numeric field data (with reference to the right figure of Figure 10) of tremulous pulse is as the object of position alignment. Here, when as when obtaining along seasonal effect in time series 3 D X-ray CT image data set, position Put aligned portions 156b and will extract coronary artery from ED three dimensional analysis view data And the data obtained that is three-dimensional Contrast Area numeric field data are as the object of position alignment.It addition, this Embodiment such as can also use X ray CT device 300 or image processing apparatus 500 to carry out Dividing processing and the three-dimensional Contrast Area numeric field data that obtains.
Here, in the 1st embodiment, position alignment portion 156b can also non-use position inspection Examining system, and carry out position alignment process.Such as, position alignment portion 156b adjusts three dimensions On position and the angle of 3 axles to regulation phase three-dimensional ultrasonic view data from The projection image that obtains of multiple viewpoint direction projections each other with the 3 D X-ray CT to regulation phase The projection image that view data obtains from the projection of multiple viewpoint direction overlaps each other.Thus, position pair Quasi-portion 156b carries out three-dimensional ultrasonic view data and the 3 D X-ray CT image of same phase The position alignment of data.By this process, position alignment portion 156b can carry out same phase Three dimensional analysis data and the position alignment of three-dimensional Contrast Area numeric field data.
Further, output unit 157a will be to " the analysis result as three-dimensional ultrasonic view data Analyze view data " and " the 2nd three-dimensional medical image data " addition of, and " position alignment is believed Breath " data as output data export.The three-dimensional medical image data in above-mentioned the 2nd also may be used Being to extract " particular organization of mappedization " from the 2nd three-dimensional medical image data and obtain " the three-dimensional map region image data " arrived.Specifically, output unit 157a will be with for the moment The three dimensional analysis data of phase and three-dimensional Contrast Area numeric field data and position alignment information are as output data Send to obtaining section 221a.Obtaining section 221a can use position alignment information, such as Figure 11 Shown in, when by three dimensional analysis data and three-dimensional Contrast Area numeric field data position alignment, join It is placed in three dimensions.
Or, medical image data three-dimensional to analysis view data and the 2nd is entered by output unit 157a The generated data that line position is directed at and synthesizes exports as output data.Above-mentioned the 2nd is three-dimensional Medical image data can also be to extract " mappedization from the 2nd three-dimensional medical image data Particular organization " and the three-dimensional map region image data that obtains.Specifically, output unit 157a will carry out position pair to three dimensional analysis data and the three-dimensional Contrast Area numeric field data of same phase Generated data that is accurate and that synthesize exports as output data.This generated data becomes shown in Figure 11 As data.It addition, when using generated data as output data, output unit 157a It is configured to that there is " the three-dimensional ultrasonic image allowed hand over as the 1st three-dimensional medical image data Data (three dimensional analysis data) " with " the three-dimensional radiography as the 2nd three-dimensional medical image data View data (three-dimensional Contrast Area numeric field data) " display and spy that is non-display and that can separate Determine the data of information.
That is, the three-dimensional image data (three-dimensional Contrast Area numeric field data) of generated data is used for The process of obtaining section 221a, three-dimensional ultrasonic view data (three dimensional analysis data) eventually through Display part 223 shows.Show and non-display therefore, it is intended that these 2 data allow hand over, And can separate.Such as, output unit 157a uses brightness value as customizing messages, three-dimensional is divided Analysis view data is as the data being made up of the brightness value of 511 gray scales in 512 gray scales, by three-dimensional Contrast Area numeric field data as the data being made up of the brightness value of 1 gray scale in 512 gray scales to generate conjunction Become data.
It addition, can also be in the present embodiment, use three-dimensional radiography figure as output data As data, the image processing part 226 that radiographic apparatus 200 is had is from three-dimensional radiography figure As extracting data three-dimensional Contrast Area numeric field data.
Further, obtaining section 221a of radiographic apparatus 200 receives output data.Further, Obtaining section 221a uses output data to perform x-ray imaging view data and ultrasound image data Position alignment.Figure 12 and Figure 13 is for illustrating that the X involved by the 1st embodiment penetrates The figure of one example of the process that ray diagnosis apparatus is carried out.
First, by the control of obtaining section 221a, radiographic apparatus 200 is by subject P Heart from multiple directions radiography photograph, generate multiple x-ray imaging view data.Such as, By the control of obtaining section 221a, X-ray tube 212 as shown in figure 12, from the 1st direction to Subject P X-ray irradiation, X-ray detector 216 has passed through tested at the 1st angle detecting The X-ray of body P.Thus, image data generating section 224 generates the X-ray in the 1st direction and makes Shadow view data.It addition, such as, by the control of obtaining section 221a, X-ray tube 212 is such as Shown in Figure 12, from the 2nd direction to subject P X-ray irradiation, X-ray detector 216 exists 2nd angle detecting has passed through the X-ray of subject P.Thus, image data generating section 224 Generate the x-ray imaging view data in the 2nd direction.
Further, obtaining section 221a uses the x-ray imaging view data and the 2nd in the 1st direction The x-ray imaging view data in direction and output data, obtain the three-dimensional position letter of particular organization Breath.Further, since particular organization is coronary artery, therefore, the x-ray imaging in the 1st direction The x-ray imaging view data in view data and the 2nd direction becomes the X-ray of tremulous pulse phase and makes Shadow view data.Wherein, when particular organization is Coronary vein, the X ray picture in the 1st direction As the X-ray image data of data and the 2nd direction becomes the x-ray imaging image of vein phase Data.
Obtaining section 221a as shown in figure 13, by being extracted by three-dimensional Contrast Area numeric field data The coronary artery that the x-ray imaging view data in coronary artery and 2 directions is depicted respectively is built Vertical correspondence, obtains the three dimensional local information coronarius of three-dimensional Contrast Area numeric field data.This is right The correspondence establishment being to carry out according to traveling path coronarius should be set up, become more than 3 Correspondence establishment.
First, three-dimensional Contrast Area numeric field data is configured at radiographic apparatus by obtaining section 221a The 3-D photography space of 100.Here, the position of configuration three-dimensional Contrast Area numeric field data is such as by grasping Author sets.Or, allocation position position the most set in advance.Further, obtaining section 221a makes image processing part 226 generate (crown dynamic for the particular organization of three-dimensional Contrast Area numeric field data Arteries and veins) respectively to multiple X-ray image data project after projection image.Such as, obtaining section is passed through The control of 221a, image processing part 226 generates and will be configured at the three-dimensional radiography in 3-D photography space Area data is respectively to the 1st direction and the projection image of the 2nd direction projection.
Further, the display part 223 control by obtaining section 221a, display is respectively to multiple X Projection image after the numeric field data of ray contrast view data projection three-dimensional Contrast Area.Further, obtaining section 221a according to reference to the operator of display part 223 respectively in multiple x-ray imaging view data In the position corresponding with particular organization, corresponding operation is set up in the position of projection image, obtain Three dimensional local information.Such as, operator moves operation (correspondence establishment operation), so that Must projection image coronarius be overlapped according to each x-ray imaging view data identification is crown Tremulous pulse.
It addition, operator moves operation, so that projection image and X-ray image data institute The coronary artery depicted is the most overlapping.Obtaining section 221a is according to the amount of movement of projection image and shifting Dynamic direction, carry out being configured at 3-D photography space three-dimensional Contrast Area numeric field data move in parallel or In rotary moving, and using carried out these process after three-dimensional Contrast Area numeric field data position as Three dimensional local information obtains.According to three dimensional local information and three-dimensional Contrast Area numeric field data and three Dimension analyzes the relative position relationship of view data, and three dimensional analysis view data passes through obtaining section 221a, is reconfigured in 3-D photography space.It addition, also sometimes through mobile operation, to throwing Image is amplified, reduces or deforms.Now, three-dimensional Contrast Area numeric field data is at 3-D photography Space is amplified, reduces or deforms.Now, three dimensional analysis view data is by taking Portion 221a, on the basis of being reconfigured in 3-D photography space, be amplified, reduce or Person deforms.
Further, image processing part 226 will be reconfigured in 3-D photography according to three dimensional local information The three dimensional analysis view data in space or be reconfigured in three-dimensional according to three dimensional local information and take the photograph Shadow space also " amplify, reduce or deform " after three dimensional analysis view data to doctor Photograph the x-ray imaging view data of heart of the subject P obtained in real time in desired direction Projection.That is, three after image processing part 226 generates position alignment in 3-D photography space The projection image of dimension analysis view data is overlapped in the picture number of the x-ray imaging view data of heart According to.It addition, so-called direction desired by doctor refer to be suitable for indwelling electrode for X-ray Image data carries out the direction photographed.It addition, the direction desired by doctor can be in operation In at random change, image processing part 226 by three dimensional analysis view data to the side after change To the x-ray imaging view data projection of the heart of the subject P obtained that photographs in real time.
Figure 14 is to represent the figure of an example of the view data of display in the 1st embodiment. Doctor can be while with reference to view data X exemplified by Figure 14, in three dimensional analysis view data Projection image confirms asynchronous position, the intravenous of the position nearest at asynchronous position, Indwelling electrode.It addition, the projection image of three dimensional analysis view data is overlapping image, therefore, Can switch show and non-display according to the requirement of operator.Here, present embodiment is also The projection objects being overlapped in the three dimensional analysis view data of X-ray image data can be only used as Asynchronous position.It addition, the projection image of the three dimensional analysis view data of overlap can be changed to appoint The opacity of meaning.It addition, in 3-D photography space the three dimensional analysis picture number of position alignment According to projection image be not limited to x-ray imaging view data by overlapping X-ray image data. In 3-D photography space, the projection image of the three dimensional analysis view data of position alignment is by overlapping X Radiographic image data can also be when being not injected into contrast agent, desired by doctor Direction carries out the X-ray image data obtained of photographing.
It addition, the 1st embodiment can also be using the three-dimensional as the 1st three-dimensional medical image data Ultrasound image data is contained in output data and exports.Now, it is overlapped in desired by doctor The view data of X-ray image data that obtains of direction photography become based on three-dimensional ultrasonic figure View data as data.View data based on this three-dimensional ultrasonic view data is e.g. wrapped The ultrasound image data of multiple brchypinacoids of the brchypinacoid containing asynchronous position.
Then, Figure 15 and Figure 16 is used, at the image involved by the 1st embodiment The flow process of the process of reason system 1 illustrates.Figure 15 is for illustrating involved by the 1st embodiment And the flow chart of an example of process that carries out of diagnostic ultrasound equipment, Figure 16 is for saying The stream of one example of the process that the radiographic apparatus involved by bright 1st embodiment is carried out Cheng Tu.It addition, Figure 15 represents one detecting system of use, finishing two-dimensional ultrasonic image One of the process that data are carried out after being directed at the initial position of 3 D X-ray CT view data Example.
Diagnostic ultrasound equipment as shown in figure 15 as example, involved by the 1st embodiment The 100 three-dimensional ultrasonic image data set (step S101) collecting heart.Further, analysis portion 156a generates three dimensional analysis image data set (step S102).Further, position alignment portion 156b Carry out at the three dimensional analysis view data of same phase and the position alignment of three-dimensional Contrast Area numeric field data Reason (step S103).
Further, output unit 157a such as will be to three dimensional analysis view data and three-dimensional radiography number of regions The generated data synthesized according to carrying out position alignment is as output data, output output data (step Rapid S104), end processes.
Further, the radiodiagnosis as shown in figure 16 as example, involved by the 1st embodiment Obtaining section 221a that device 200 is had determines whether to receive from diagnostic ultrasound equipment 100 Output data (step S201).Here, when do not receive output data time (step S201 Negative), obtaining section 221a is standby to receiving output data.
On the other hand, (step S201 is certainly), obtaining section 221a when receiving output data Control each portion of radiographic apparatus 200, generate the x-ray imaging picture number of multiple directions According to (step S202).Specifically, radiographic apparatus 200 from multiple directions to tremulous pulse The heart of the subject P of phase is photographed.
Further, by the control of obtaining section 221a, multiple X-ray are made by display part 223 respectively Shadow view data, three-dimensional Contrast Area numeric field data (step S203) of projection overlap display.Further, Obtaining section 221a determines whether to receive from operator the crown of x-ray imaging view data to be moved Arteries and veins sets up corresponding correspondence establishment operation (step S204) with projection image.Here, ought not connect When being operated by correspondence establishment (step S204 negative), obtaining section 221a is standby to accepting correspondence Set up operation.
On the other hand, (step S204 is certainly), obtaining section when receiving correspondence establishment operation 221a operates according to correspondence establishment, obtains the three-dimensional position coronarius in 3-D photography space Information (step S205).Further, by the control of obtaining section 221a, display part 223 shows Show three dimensional analysis image data location in alignment with the view data after x-ray imaging view data (step S206), and terminate to process.
As it has been described above, in the 1st embodiment, by making three-dimensional ultrasonic view data and two The position alignment of X-ray image data of dimension alternate in 3 D X-ray CT view data (or, Three-dimensional MRI image data) carry out.That is, in the 1st embodiment, by using position The position detecting system of sensor 160, it is possible in 3 D X-ray CT view data differentiate with The region that the scanning area of three-dimensional ultrasonic view data is corresponding, it addition, can be according to these 2 The organizational information that region is depicted respectively, carries out the position alignment between volume data according to voxel grade.
Thus, in the 1st embodiment, it is possible to easily carry out based on ultrasound image data The position alignment of three dimensional analysis view data and three-dimensional Contrast Area numeric field data.Further, since hat Shape tremulous pulse has distinctive form, therefore, it is possible to easily carry out the three-dimensional Contrast Area of tremulous pulse phase The position alignment of numeric field data and the x-ray imaging view data of tremulous pulse phase.That is, implement the 1st In mode, it is possible to carry out ultrasound image data (three dimensional analysis view data) and make with X-ray The position alignment of shadow view data.Thus, in the 1st embodiment, it is possible to saturating in X-ray The position determined by ultrasonic diagnosis depending on lower differentiation.It addition, in the 1st embodiment, doctor Teacher can be while with reference to can the throwing of three dimensional analysis view data of overlapping display by position alignment Image, at asynchronous near sites indwelling electrode.
(the 2nd embodiment)
In the 1st embodiment, obtain three dimensional local information for the operation according to operator Situation is illustrated.In the 2nd embodiment, for not carrying out the operation of operator, and Automatically obtain the situation of three dimensional local information, use Figure 17 to illustrate.Figure 17 be for The figure of the 2nd embodiment is described.
Image processing system 1 involved by 2nd embodiment is real with use Fig. 1 explanation the 1st Execute the image processing system 1 involved by mode to constitute in the same manner.Wherein, as the 2nd embodiment party Obtaining section 221a in the 2nd position alignment portion involved by formula is when according to photographing at multiple photography directions When the multiple X-ray image data obtained carry out position alignment process, pass through 3 d image data Between pattern match carry out the 2nd three-dimensional medical image data and rebuild multiple X-ray image data The position alignment of the three-dimensional X-ray image data obtained processes.Such as, the 2nd embodiment institute Obtaining section 221a related to carries out three-dimensional radiography figure by the pattern match between 3 d image data The 3 D X-ray contrastographic picture number obtained with the multiple x-ray imaging view data of reconstruction as data According to position alignment process.As pattern match process, it is possible to list use be mutually associated or The process of auto-correlation, mutual information amount, standardization mutual information amount, correlation ratio etc..
The data comprised when output data are the three-dimensionals extracted from three-dimensional image data During the numeric field data of Contrast Area, the object of pattern match becomes three-dimensional Contrast Area numeric field data.It addition, example As, by the control of obtaining section 221a, image processing part 226 will be by photographing in multiple directions The x-ray imaging view data obtained, to 3-D photography space back projection, is rebuild three-dimensional X and is penetrated Line image data.Such as, in the 2nd embodiment, 3 D X-ray contrastographic picture number According to according in 2 directions, 3 directions or 50 directions photograph the x-ray imaging obtained View data is rebuild.
Here, in order to alleviate the load that pattern match processes, for example, it is desirable to carry out following place Reason.That is, as obtaining section 221a in the 2nd position alignment portion at the 2nd three-dimensional medical image data Three-dimensional Region Of Interest and the three-dimensional set in three-dimensional X-ray image data of middle setting are concerned about Position alignment process is carried out between region.Such as, obtaining section 221a is in three-dimensional image data The three-dimensional Region Of Interest set in (or, three-dimensional Contrast Area numeric field data) is penetrated with at three-dimensional X Position alignment process is carried out between the three-dimensional Region Of Interest set in line image data.
Such as, operator as shown in figure 17, sets three-dimensional ROI to three-dimensional Contrast Area numeric field data (region Of Interest).Thus, such as image processing part 226 extracts as three-dimensional " volume data E " of the three-dimensional Contrast Area numeric field data of ROI.It addition, operator is as shown in figure 17, By respectively 2 x-ray imaging view data being set two dimension ROI, set three-dimensional ROI. Thus, image processing part 226 rebuilds the 3 D X-ray image data as three-dimensional ROI " volume data F ".It addition, these three-dimensional ROI can also be according to brightness value by obtaining section 221a Automatically set.
Further, obtaining section 221a by volume data E and volume data F are carried out pattern match, from And carry out position alignment process, obtain the three-dimensional position of particular organization's (such as, coronary artery) Information.Above-mentioned process such as can also use multiple when inserting seal wire Multiple X-ray image data that direction photography obtains carry out rebuilding the three-dimensional X-ray image obtained Data are carried out.It addition, its later processing and the process phase of explanation in the 1st embodiment With, therefore omit the description.
Then, Figure 18 is used, for the image processing system 1 involved by the 2nd embodiment The flow process processed illustrates.Figure 18 is for the X-ray involved by the 2nd embodiment is described The flow chart of one example of the process that the diagnostic equipment is carried out.It addition, involved by the 1st embodiment And diagnostic ultrasound equipment 100 carry out process with in the 1st embodiment explanation process Identical, therefore omit the description.
Radiographic apparatus as shown in figure 18 as example, involved by the 2nd embodiment 200 obtaining sections 221a being had determine whether to receive output from diagnostic ultrasound equipment 100 Data (step S301).Here, when being not received by exporting data, (step S301 is no Fixed), obtaining section 221a is standby to receiving output data.
On the other hand, (step S301 is certainly), obtaining section 221a when receiving output data Control each portion of radiographic apparatus 200, generate the x-ray imaging picture number of multiple directions According to (step S302).Specifically, radiographic apparatus 200 from multiple directions to tremulous pulse The heart of the subject P of phase is photographed.
Further, obtaining section 221a accepts the setting (step S303) of three-dimensional ROI.Further, Obtaining section 221a extracts the three-dimensional Contrast Area numeric field data of three-dimensional ROI, according to multiple x-ray imagings View data rebuilds the 3 D X-ray image data (step S304) of three-dimensional ROI.And And, the three-dimensional X of the obtaining section 221a three-dimensional Contrast Area numeric field data at three-dimensional ROI and three-dimensional ROI Pattern match (step S305) is carried out between ray contrast view data.
Further, the three-dimensional position coronarius letter during obtaining section 221a obtains 3-D photography space Breath (step S306).Further, by the control of obtaining section 221a, display part 223 shows By three dimensional analysis image data location in alignment with the view data after x-ray imaging view data (step S307), end processes.
As it has been described above, in the 2nd embodiment, it is possible to automatically carry out the three-dimensional of particular organization Positional information.Thus, in the 2nd embodiment, it is possible to more easily carry out ultrasonography Data (three dimensional analysis view data) and the position alignment of x-ray imaging view data.
It addition, the process in each portion of explanation also may be used in the 1st and the 2nd above-mentioned embodiment To be performed by X ray CT device 300 or image processing apparatus 500.Such as, image is analyzed At the position alignment of the generation process of data, ultrasound image data and X ray CT view data Reason, the output of output data process, the acquirement of the three dimensional local information of particular organization processes one Some or all of can also be performed by X ray CT device 300 or image processing apparatus 500. The overlay chart picture of the analysis view data after position alignment and X-ray image data can also be by X Ray CT apparatus 300 or image processing apparatus 500 generate.That is, the above-mentioned the 1st and In 2 embodiments, the dispersion/comprehensive concrete mode in each process portion of explanation is not limited to figure Show, it is possible to according to various loads or behaviour in service etc., the functional or physics with arbitrary unit Property ground dispersion/comprehensively its all or part constitute.
It addition, in the 1st and the 2nd above-mentioned embodiment, for the 1st three-dimensional medical figure As data are three-dimensional ultrasonic view data, the 2nd three-dimensional medical image data is by particular organization The 3 D X-ray CT view data of reflectionization or the situation of three-dimensional MRI image data are entered Row explanation.But, if the 1st three-dimensional medical image data is can be to the motion of regulation tissue The three-dimensional medical image data being analyzed, the 2nd three-dimensional medical image data is to particular organization The three-dimensional medical image data that reflectionization obtains, then can be useful in above-mentioned the 1st and the 2nd The content of explanation in embodiment.Such as, in the 1st and the 2nd embodiment in explanation It is to carry out cardiac muscle contaminating the three of the phase of shadow that appearance can also be applicable to the 1st three-dimensional medical image data Dimension MRI image data, the 2nd three-dimensional medical image data is to coronary artery or Coronary vein The situation of the 3 D X-ray CT view data of the phase of dye shadow.Or, such as the 1st and In 2nd embodiment, the content of explanation can also be applicable to the 1st three-dimensional medical image data is right Cardiac muscle carries out contaminating the 3 D X-ray CT view data of the phase of shadow, the 2nd three-dimensional medical imaging number According to being the situation that Coronary vein carries out contaminating the 3 D X-ray CT view data of the phase of shadow.
It addition, the image processing method energy illustrated in the 1st and the 2nd above-mentioned embodiment Enough by the computer such as personal computer or the work station preprepared image processing program of execution Realize.This image processing program can be issued via networks such as the Internets.It addition, this figure As processing routine is recorded in the computer such as hard disk, floppy disk (FD), CD-ROM, MO, DVD can In the record medium read, by being read out execution by computer from record medium.
Above, as described, according to the 1st and the 2nd embodiment, it is possible at X The position determined by ultrasonic diagnosis is differentiated under actinoscopy X.
Although the description of several embodiments of the invention, but these embodiments are as an example And point out, it is not intended to limit the scope of the present invention.These embodiments can each with other Kind of mode is implemented, within a range not departing from the gist of the invention, it is possible to carry out various omission, Displacement, change.These embodiments or its deformation be contained in the scope of invention or purport one Sample, is contained in the invention of claims record and the scope of equalization thereof.

Claims (9)

1. an image processing system, wherein, possesses:
1st position alignment portion, it carries out obtained of photographing the regulation tissue of subject Position alignment between 1 three-dimensional medical image data and the 2nd three-dimensional medical image data；
Output unit, it will be to the above-mentioned 1st three-dimensional medical image data and the above-mentioned 2nd three-dimensional doctor Addition of the data of position alignment information or to the 1st three-dimensional medical imaging number by view data Generated data conduct after synthesizing according to carrying out position alignment with the 2nd three-dimensional medical image data Output data export；
2nd position alignment portion, it receives above-mentioned output data, carries out the above-mentioned 2nd three-dimensional medical View data and the above-mentioned regulation tissue of above-mentioned subject is entered from 1 or multiple photography direction Between 1 corresponding with photography direction or multiple X-ray image data that row is photographed and obtained Position alignment；And
Display part, it is according to above-mentioned 1st position alignment portion and above-mentioned 2nd position alignment portion Position alignment result, shows the above-mentioned 1st three-dimensional medical image data position alignment in above-mentioned The X-ray image data of regulation tissue and the view data that obtains,
Above-mentioned 1st three-dimensional medical image data is that the motion can organized above-mentioned regulation is carried out point The three-dimensional medical image data of analysis, the above-mentioned 2nd three-dimensional medical image data is can to penetrate according to X Three-dimensional medical image data after particular organization's mappedization of line image discriminating data,
Above-mentioned 2nd position alignment portion carry out position alignment process above-mentioned 1 or multiple X penetrates Line image data are above-mentioned regulation tissue to carry out radiography photography obtain 1 or multiple X penetrate Line image data or the above-mentioned particular organization being inserted into utensil is photographed and 1 or the multiple X-ray image data obtained,
Above-mentioned 2nd position alignment portion according to above-mentioned 2nd three-dimensional medical image data with above-mentioned 1 Or the position alignment result between multiple X-ray image data, obtains radioscopic image number According to 3-D photography space in the three dimensional local information of above-mentioned particular organization,
Above-mentioned display part is three-dimensional according to the three dimensional local information of above-mentioned particular organization and the above-mentioned 1st Relative position relation between medical image data and the above-mentioned 2nd three-dimensional medical image data, comes Show by the above-mentioned 1st three-dimensional medical image data or by the above-mentioned 1st three-dimensional medical imaging The analysis image data location that data are analyzed and generate is aligned the X organized in above-mentioned regulation Radiographic image data and the view data that obtains.
Image processing system the most according to claim 1, wherein,
When the above-mentioned 2nd three-dimensional medical image data is configured at above-mentioned 3-D photography space, on State display part to show above-mentioned particular organization projects to above-mentioned 1 or multiple radioscopic image number According to and the projection image that obtains,
Above-mentioned 2nd position alignment portion utilizes above-mentioned 1 according to the operator with reference to above-mentioned display part Or multiple X-ray image data are by the position corresponding with above-mentioned particular organization and above-mentioned projection The operation of corresponding relation is set up in the position of picture, obtains above-mentioned three dimensional local information.
Image processing system the most according to claim 1, wherein,
When carrying out position alignment process according to multiple X-ray image data, above-mentioned 2nd position Aligned portions, by the pattern match between 3 d image data, carries out above-mentioned 2nd three-dimensional medical figure As data and above-mentioned multiple X-ray image data are rebuild the three-dimensional X-ray image obtained Position alignment between data processes.
Image processing system the most according to claim 3, wherein,
The three-dimensional that above-mentioned 2nd position alignment portion sets in the above-mentioned 2nd three-dimensional medical image data Enter between Region Of Interest and the three-dimensional Region Of Interest set in above-mentioned three-dimensional X-ray image data Line position registration process.
Image processing system the most according to claim 1, wherein,
When using above-mentioned generated data as above-mentioned output data, it is configured to that there is above-mentioned output unit Allow hand over the above-mentioned 1st three-dimensional medical image data and the above-mentioned 2nd three-dimensional medical image data Display and non-display and while the data of the customizing messages that can separate.
Image processing system the most according to claim 1, wherein,
Above-mentioned output unit is using dividing the analysis result as the above-mentioned 1st three-dimensional medical image data Analysis view data and the above-mentioned 2nd three-dimensional medical image data addition of the number of position alignment information According to or medical image data three-dimensional to this analysis view data and the 2nd carry out position alignment And the generated data synthesized exports as above-mentioned output data.
Image processing system the most according to claim 1, wherein,
Above-mentioned 1st three-dimensional medical image data is three-dimensional ultrasonic view data, the above-mentioned 2nd three Dimension medical image data is 3 D X-ray CT view data or three-dimensional MRI image data.
8. a radiographic apparatus, wherein, possesses:
2nd position alignment portion, obtains as according to the position alignment result in the 1st position alignment portion Output data, above-mentioned 2nd position alignment portion receives and obtains the regulation tissue photography of subject The 1st three-dimensional medical image data addition of position alignment with the 2nd three-dimensional medical image data and believe The data of breath or by three-dimensional to the 1st three-dimensional medical image data and the 2nd medical image data The generated data carrying out position alignment and synthesize, carry out above-mentioned 2nd three-dimensional medical image data with The above-mentioned regulation tissue of above-mentioned subject is photographed from 1 or multiple photography direction obtain with Position alignment between 1 or multiple X-ray image data that photography direction is corresponding；With
Display part, it is according to above-mentioned 1st position alignment portion and the position of above-mentioned 2nd position alignment Put alignment result, show the above-mentioned 1st three-dimensional medical image data position alignment in above-mentioned rule The X-ray image data of fixed tissue and the view data that obtains,
Above-mentioned 1st three-dimensional medical image data is that the motion can organized above-mentioned regulation is carried out point The three-dimensional medical image data of analysis, the above-mentioned 2nd three-dimensional medical image data is can to penetrate according to X Three-dimensional medical image data after particular organization's mappedization of line image discriminating data,
Above-mentioned 2nd position alignment portion carry out position alignment process above-mentioned 1 or multiple X penetrates Line image data are above-mentioned regulation tissue to carry out radiography photography obtain 1 or multiple X penetrate Line image data or the above-mentioned particular organization being inserted into utensil is photographed and 1 or the multiple X-ray image data obtained,
Above-mentioned 2nd position alignment portion according to above-mentioned 2nd three-dimensional medical image data with above-mentioned 1 Or the position alignment result between multiple X-ray image data, obtains radioscopic image number According to 3-D photography space in the three dimensional local information of above-mentioned particular organization,
Above-mentioned display part is three-dimensional according to the three dimensional local information of above-mentioned particular organization and the above-mentioned 1st Relative position relation between medical image data and the above-mentioned 2nd three-dimensional medical image data, comes Show by the above-mentioned 1st three-dimensional medical image data or by the above-mentioned 1st three-dimensional medical imaging The analysis image data location that data are analyzed and generate is aligned the X organized in above-mentioned regulation Radiographic image data and the view data that obtains.
9. an image processing method, wherein, including:
1st position alignment portion carry out the regulation tissue of subject is photographed and obtain the 1st Position alignment between three-dimensional medical image data and the 2nd three-dimensional medical image data, wherein, Above-mentioned 1st three-dimensional medical image data is can be analyzed the motion that above-mentioned regulation is organized Three-dimensional medical image data, the above-mentioned 2nd three-dimensional medical image data is can be according to X ray picture As the three-dimensional medical image data after particular organization's mappedization of discriminating data,
Output unit will be to the above-mentioned 1st three-dimensional medical image data and above-mentioned 2nd three-dimensional medical figure As data addition of the data after position alignment information or to the 1st three-dimensional medical image data The generated data carrying out position alignment with the 2nd three-dimensional medical image data and synthesize is as output Data export,
2nd position alignment portion receives above-mentioned output data, carries out the above-mentioned 2nd three-dimensional medical imaging Data and the above-mentioned regulation tissue of above-mentioned subject is taken the photograph from 1 or multiple photography direction Position between 1 corresponding with photography direction or multiple X-ray image data that shadow obtains Alignment, according to the above-mentioned 2nd three-dimensional medical image data and above-mentioned 1 or multiple X ray picture As the position alignment result between data, obtain the 3-D photography space of X-ray image data In the three dimensional local information of above-mentioned particular organization,
Display part is medical according to three dimensional local information and above-mentioned 1st three-dimensional of above-mentioned particular organization Relative position relation between view data and the above-mentioned 2nd three-dimensional medical image data, shows By the above-mentioned 1st three-dimensional medical image data or by the above-mentioned 1st three-dimensional medical image data The image data location of analyzing being analyzed and generate is aligned the X-ray organized in above-mentioned regulation View data and the view data that obtains, thus according to above-mentioned 1st position alignment portion and above-mentioned The position alignment result in the 2nd position alignment portion, shows the above-mentioned 1st three-dimensional medical imaging number The X-ray image data organized in above-mentioned regulation according to position alignment and the view data obtained,
Above-mentioned 2nd position alignment portion carry out position alignment process above-mentioned 1 or multiple X penetrates Line image data are above-mentioned regulation tissue to carry out radiography photography obtain 1 or multiple X penetrate Line image data or the above-mentioned particular organization being inserted into utensil is photographed and 1 or the multiple X-ray image data obtained.
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