CN103788330B - A kind of flexible hydrophilic contact lens makes formula - Google Patents
A kind of flexible hydrophilic contact lens makes formula Download PDFInfo
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- CN103788330B CN103788330B CN201410010857.1A CN201410010857A CN103788330B CN 103788330 B CN103788330 B CN 103788330B CN 201410010857 A CN201410010857 A CN 201410010857A CN 103788330 B CN103788330 B CN 103788330B
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- contact lens
- flexible hydrophilic
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- evaporimeter
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
- C08G18/72—Polyisocyanates or polyisothiocyanates
- C08G18/73—Polyisocyanates or polyisothiocyanates acyclic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
- C08F220/28—Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/62—Polymers of compounds having carbon-to-carbon double bonds
- C08G18/6216—Polymers of alpha-beta ethylenically unsaturated carboxylic acids or of derivatives thereof
- C08G18/625—Polymers of alpha-beta ethylenically unsaturated carboxylic acids; hydrolyzed polymers of esters of these acids
- C08G18/6254—Polymers of alpha-beta ethylenically unsaturated carboxylic acids and of esters of these acids containing hydroxy groups
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
- G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
-
- G—PHYSICS
- G02—OPTICS
- G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
- G02C7/00—Optical parts
- G02C7/02—Lenses; Lens systems ; Methods of designing lenses
- G02C7/04—Contact lenses for the eyes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/26—Esters containing oxygen in addition to the carboxy oxygen
- C08F220/28—Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety
- C08F220/281—Esters containing oxygen in addition to the carboxy oxygen containing no aromatic rings in the alcohol moiety and containing only one oxygen, e.g. furfuryl (meth)acrylate or 2-methoxyethyl (meth)acrylate
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- General Health & Medical Sciences (AREA)
- Eyeglasses (AREA)
Abstract
The invention discloses a kind of flexible hydrophilic contact lens and make formula, relate to contact lens and manufacture field, mainly include following components: ethylene glycol: 500 grams, methyl methacrylate: 25 grams, methacrylic acid: 20, gram styrene: 20 grams, butyl acetate: 800 grams, second one mercaptoethanol: 10 grams, propyleneglycoles: 100 grams, hydroxyethyl methylacrylate: 1000 grams, hexamethylene diisocyanate: 5 grams.The flexibility of flexible hydrophilic corneal contact lens out made by the present invention is good, elastic good, is difficult to fade, more stable when being shaped and paint, and the flexible hydrophilic corneal contact lens after making is worn and the most comfortable do not had strong impulse effect.
Description
Technical field:
The present invention relates to contact lens and manufacture field, be specifically related to a kind of flexible hydrophilic corneal contact lens
Sheet makes formula.
Background technology:
Contact lens, or corneal contact lens, be that one is worn on cornea, in order to correct defects of vision or to protect
The eyeglass of eye protection eyeball.It includes rigid and soft two kinds, contact lens not only from appearance with convenience side
Face brings the biggest improvement to the ametropia patient such as myopia, hypermetropia, astigmatism, and the visual field is broad,
True to nature depending on thing, this external control adolescent myopia, astigmatism develop, and treat the aspects such as special oculopathy and also send out
Wave special effect.But what great majority used at present is all soft contact lens, because of the hardness of material
Difference, so being easier to split and be scraped off.The user having part often reflects that the edge of eyeglass goes out
Existing slight crack and breach.By analysis, it is common that fingernail scratch eyeglass, too bend eyeglass, eyeglass adhesion,
Dehydration becomes fragile and protein to accumulate be too much the reason of lens breakage.
For first contact lens wear or the friend of colorful contact lens, can not feel like oneself, one of which
Possible reason is just because: cornea anoxia.Under normal circumstances, our cornea needs " breathing ",
The oxygen transmission rate of contact lens is important indicator, therefore a lens materials of assessment contact lens material quality
Having higher oxygen transmission rate is to select one critically important factor of eyeglass.
Cornea long term hypoxia is easily caused the related complication of cornea, the chronicest corneal edema, cornea rebirth blood
Pipes etc., contact lens especially colorful contact lens meets the demand of numerous people seeking beauty, but must
Test by the program of specification and join oneself contact lens products applicable, and carry out daily in strict accordance with care program
Nursing.It is specifically intended that the oxygen transmission rate of the eyeglass of unlike material has the biggest difference, can wear time
Between the most just have the biggest difference.The most well avoid the cornea caused because of long-time contact lens wear
Oxygen deficit problem, can wear continuously with ultra-long time, meets the demand of nap simultaneously.And contact lens
Human eye also can be impacted by hydrophilic and oxygen permeability to a great extent.
Summary of the invention:
The technical problem to be solved is to provide a kind of flexibility good, elastic good, is difficult to fade
Flexible hydrophilic contact lens make formula.
The technical problem to be solved uses following technical scheme to realize:
A kind of flexible hydrophilic contact lens makes formula and includes following components:
Ethylene glycol: 500 grams
Methyl methacrylate: 25 grams
Methacrylic acid: 20 grams
Styrene: 20 grams
Butyl acetate: 800 grams
Second one mercaptoethanol: 10 grams
Propyleneglycoles: 100 grams
Hydroxyethyl methylacrylate: 1000 grams
Hexamethylene diisocyanate: 5 grams
Making step according to the corneal contact lens made by flexible hydrophilic corneal contact lens making formula
For:
1, by preprepared ethylene glycol, methyl methacrylate, methacrylic acid, styrene,
Butyl acetate, second one mercaptoethanol, propyleneglycoles, hydroxyethyl methylacrylate are sequentially placed into rotation
Evaporimeter mixes；
2, the revolution of Rotary Evaporators is arranged on 450 revs/min, the most slowly Rotary Evaporators is carried out
Heat；
Stopping when 3, temperature adds to 70 DEG C heating, the rotating speed rotation 2 continuing to keep 450 revs/min is little
Time；
4, after 2 hours, hexamethylene diisocyanate is joined rotation by the rotation of the evaporimeter that stops the rotation
Turn in evaporimeter, then make it naturally cool to room temperature, rear placement 30 points naturally under normal temperature condition to be achieved
Clock；
5, the Rotary Evaporators after cooling down is put into and is carried out cold preservation in 0-5 ° of cold room 12 hours, then
Taking out, the now raw material configuration work of flexible hydrophilic corneal contact lens completes.
The hydrophilic using the flexible hydrophilic corneal contact lens of above method and formula making typically can reach
30%-80%, hydrophilic and high oxygen permeability are preferable, the most normally wear and the most also human eye will not be caused stimulation
Impact, extends wear time and improves the protection to human eye, and elastomeric effect also makes wearer
More comfortable, extend the service life of glasses.
The invention has the beneficial effects as follows: connect according to the flexible hydrophilic cornea that this formula and method are made
The flexibility touching mirror is good, elastic good, is difficult to fade, more stable when being shaped and paint, and makes
After flexible hydrophilic corneal contact lens wear and the most comfortable do not have strong impulse effect.
Detailed description of the invention:
For the technological means making the present invention realize, creation characteristic, reach purpose and effect and be readily apparent from
Solve, below in conjunction with concrete example, the present invention is expanded on further.
A kind of flexible hydrophilic contact lens makes formula and includes following components:
Ethylene glycol: 500 grams
Methyl methacrylate: 25 grams
Methacrylic acid: 20 grams
Styrene: 20 grams
Butyl acetate: 800 grams
Second one mercaptoethanol: 10 grams
Propyleneglycoles: 100 grams
Hydroxyethyl methylacrylate: 1000 grams
Hexamethylene diisocyanate: 5 grams
Making step according to the corneal contact lens made by flexible hydrophilic corneal contact lens making formula
For:
6, by preprepared ethylene glycol, methyl methacrylate, methacrylic acid, styrene,
Butyl acetate, second one mercaptoethanol, propyleneglycoles, hydroxyethyl methylacrylate are sequentially placed into rotation
Evaporimeter mixes；
7, the revolution of Rotary Evaporators is arranged on 450 revs/min, the most slowly Rotary Evaporators is carried out
Heat；
Stopping when 8, temperature adds to 70 DEG C heating, the rotating speed rotation 2 continuing to keep 450 revs/min is little
Time；
9, after 2 hours, hexamethylene diisocyanate is joined rotation by the rotation of the evaporimeter that stops the rotation
Turn in evaporimeter, then make it naturally cool to room temperature, rear placement 30 points naturally under normal temperature condition to be achieved
Clock；
10, the Rotary Evaporators after cooling down is put into and is carried out cold preservation in 0-5 ° of cold room 12 hours, then
Taking out, the now raw material configuration work of flexible hydrophilic corneal contact lens completes.
The ultimate principle of the present invention and principal character and advantages of the present invention have more than been shown and described.One's own profession
Skilled person will appreciate that of industry, the present invention is not restricted to the described embodiments, above-described embodiment and explanation
The principle that the present invention is simply described described in book, without departing from the spirit and scope of the present invention,
The present invention also has various changes and modifications, and these changes and improvements both fall within claimed invention model
In enclosing.Claimed scope is defined by appending claims and equivalent thereof.
Claims (2)
1. a flexible hydrophilic contact lens makes formula, it is characterised in that: flexible hydrophilic angle
Film adherent lens makes formula and is made up of following components:
Ethylene glycol: 500 grams
Methyl methacrylate: 25 grams
Methacrylic acid: 20 grams
Styrene: 20 grams
Butyl acetate: 800 grams
2 mercapto ethanol: 10 grams
Propyleneglycoles: 100 grams
Hydroxyethyl methylacrylate: 1000 grams
Hexamethylene diisocyanate: 5 grams.
2. the flexible hydrophilic contact lens that a kind utilizes described in claim 1 makes made by formula
The manufacture method of flexible hydrophilic contact lens be:
(1) by preprepared ethylene glycol, methyl methacrylate, methacrylic acid, benzene second
Alkene, butyl acetate, 2 mercapto ethanol, propyleneglycoles, hydroxyethyl methylacrylate are sequentially placed into rotation
Turn in evaporimeter and mix；
(2) revolution of Rotary Evaporators is arranged on 450 revs/min, the most slowly Rotary Evaporators is entered
Row is heated；
(3) stopping when temperature adds to 70 DEG C heating, the rotating speed rotation 2 continuing to keep 450 revs/min is little
Time；
After (4) 2 hours, hexamethylene diisocyanate is joined rotation by the rotation of the evaporimeter that stops the rotation
Turn in evaporimeter, then make it naturally cool to room temperature, rear placement 30 points naturally under normal temperature condition to be achieved
Clock；
(5) Rotary Evaporators after cooling down is put into and is carried out cold preservation in 0-5 ° of cold room 12 hours, then
Taking out, the now raw material configuration work of flexible hydrophilic corneal contact lens completes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410010857.1A CN103788330B (en) | 2014-01-09 | 2014-01-09 | A kind of flexible hydrophilic contact lens makes formula |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410010857.1A CN103788330B (en) | 2014-01-09 | 2014-01-09 | A kind of flexible hydrophilic contact lens makes formula |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103788330A CN103788330A (en) | 2014-05-14 |
| CN103788330B true CN103788330B (en) | 2016-08-17 |
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ID=50664414
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410010857.1A Active CN103788330B (en) | 2014-01-09 | 2014-01-09 | A kind of flexible hydrophilic contact lens makes formula |
Country Status (1)
| Country | Link |
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| CN (1) | CN103788330B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104194235B (en) * | 2014-08-25 | 2016-06-01 | 陶如意 | A kind of PMMA ophthalmic lens and its preparation method |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86100756A (en) * | 1985-01-04 | 1986-09-17 | 先灵公司 | Coloured contact lenses and manufacture method thereof |
| CN1035183A (en) * | 1987-11-24 | 1989-08-30 | 先灵公司 | Hydrophilic colored contact lenses |
| CN101017209A (en) * | 2007-02-15 | 2007-08-15 | 黄则煌 | Strong resistance to heat and hard wearing propylene diglycol carbonate resinous flat screening glass and preparation method there for |
| CN101296963A (en) * | 2005-09-07 | 2008-10-29 | 光学转变公司 | Optical elements that include curable film-forming compositions containing blocked isocyanate adhesion promoters |
| CN101508875A (en) * | 2008-02-15 | 2009-08-19 | 日东电工株式会社 | Pressure-sensitive adhesive composition for optical films, pressure-sensitive adhesive optical film and image display |
-
2014
- 2014-01-09 CN CN201410010857.1A patent/CN103788330B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN86100756A (en) * | 1985-01-04 | 1986-09-17 | 先灵公司 | Coloured contact lenses and manufacture method thereof |
| CN1035183A (en) * | 1987-11-24 | 1989-08-30 | 先灵公司 | Hydrophilic colored contact lenses |
| CN101296963A (en) * | 2005-09-07 | 2008-10-29 | 光学转变公司 | Optical elements that include curable film-forming compositions containing blocked isocyanate adhesion promoters |
| CN101017209A (en) * | 2007-02-15 | 2007-08-15 | 黄则煌 | Strong resistance to heat and hard wearing propylene diglycol carbonate resinous flat screening glass and preparation method there for |
| CN101508875A (en) * | 2008-02-15 | 2009-08-19 | 日东电工株式会社 | Pressure-sensitive adhesive composition for optical films, pressure-sensitive adhesive optical film and image display |
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| Publication number | Publication date |
|---|---|
| CN103788330A (en) | 2014-05-14 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CB03 | Change of inventor or designer information |
Inventor after: Chen Wenhe Inventor before: Li Xiufeng |
|
| CB03 | Change of inventor or designer information | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170613 Address after: 519000 Guangdong city of Zhuhai province Jinwan District Gimhae Middle Road Patentee after: Zhuhai three lions optics Co., Ltd. Address before: 242100 Lang Guanglu, town, Langxi County, Xuancheng, Anhui Patentee before: Anhui Province Langxi County Hanxing Glasses Co., Ltd. |
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| TR01 | Transfer of patent right |