CN103784765A - Pharmaceutical composition for treating pains - Google Patents
Pharmaceutical composition for treating pains Download PDFInfo
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- CN103784765A CN103784765A CN201410022482.0A CN201410022482A CN103784765A CN 103784765 A CN103784765 A CN 103784765A CN 201410022482 A CN201410022482 A CN 201410022482A CN 103784765 A CN103784765 A CN 103784765A
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Abstract
The invention discloses a pharmaceutical composition for treating pains. The composition is prepared from the following 45 raw material medicines such as medicinal cyathula roots, lycopodium clavatum, caulis Spatholobi, rhizoma dioscoreae nipponicae, liquidambar formosana hance, frankincense, myrrh, resina draconis, radix rehmanniae preparata, astragalus membranaceus, herba epimedii, radix aconiti preparata, prepared kusnezoff monkshood roots, aconitine, cortex periplocae and the like. The pharmaceutical composition disclosed by the invention is prepared into clinically accepted troches, capsules, granules, pills, oral liquids, pastes, ointments, sprays, liniments or tinctures by adding conventional auxiliary materials according to a conventional process. The pharmaceutical composition disclosed by the invention has the functions of promoting blood circulation to remove blood stasis, dispelling wind and removing obstruction in the meridians, resisting inflammation and relieving pains as well as an immunosuppressive action, has a remarkable treatment effect to pains caused by rheumatism, rheumatoid arthritis, osteoproliferation, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, lumbar disc herniation, traumatic injury, strains of lumbar muscles and sciatica, and is free from toxic and side effects.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition for the treatment of pain.
Background technology
" pain " of Chinese refers to remaining pain; " bitterly " nocuity that refers to patient body inside is felt.The so-called pain of modern medicine, is a kind of Physiological Psychology activity of complexity, is one of modal symptom clinically.It comprises that noxious stimulation acts on the caused pain of body and feels, and the pain reaction (somatic movement reaction and internal organs vegetative reaction, be often attended by strong emotion color) of body to noxious stimulation.The pain sensation can be used as the one warning that body comes to harm, and causes the protective reaction of body series of defence.But then, pain also has its limitation (while attending pain as cancer etc., late) as reporting to the police.And some long-term having an intense pain has become a kind of insufferable torment to body.Therefore, analgesia is the vital task that medical personnel faces.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition for the treatment of pain.
The present invention is achieved through the following technical solutions:
The crude drug of pharmaceutical composition of the present invention consists of:
The crude drug composition of pharmaceutical composition of the present invention is preferably:
The crude drug composition of pharmaceutical composition of the present invention is preferably:
The crude drug composition of pharmaceutical composition of the present invention is preferably:
Pharmaceutical composition of the present invention adds conventional adjuvant to make the tablet of clinical acceptance, capsule, granule, pill, oral liquid, emplastrum, ointment, spray, liniment or tincture according to common process.
Pharmaceutical composition of the present invention has blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral, antiinflammatory, analgesia, immunosuppressive action, to treating: the pain effects such as rheumatism, rheumatoid arthritis, hyperosteogeny, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, traumatic injury, lumbar muscle strain, sciatic nerve are remarkable, have no side effect.
Experimental example is used for further illustrating the present invention below, but is not limited to the present invention.
One, experimental example
1, clinical observation
Pain patients 100 examples such as treatment group anthology invention capsule (according to embodiment 1 method preparation) treatment rheumatism, rheumatoid arthritis, hyperosteogeny, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, traumatic injury, lumbar muscle strain, sciatic nerve, wherein male's 50 examples, women's 50 examples.
2, medicament selection
Treatment group: capsule of the present invention (according to embodiment 1 method preparation), treat three courses for the treatment of (9 days courses for the treatment of), every day 3 times, each 2.
3, diagnostic criteria
1.. rest pain, pain has become a part for life.
2.. when much activity more even bends over lost article found, sneeze, just fall ill, hurt like hell, function limitation.
3.. overcast and rainy or wind-engaging is caught a cold and can be caused the recurrence of pain or increase the weight of.
4, criterion of therapeutical effect
" in cure the desease Standardization of diagnosis and curative effect " of implementing with reference to State Administration of Traditional Chinese Medicine 1994 drafted as follows:
Recovery from illness: tcm clinical practice symptom, sign disappear or substantially disappear;
Effective: tcm clinical practice symptom, sign obviously change;
Effective: tcm clinical practice symptom, sign all take a favorable turn;
Invalid: tcm clinical practice symptom, sign are all not improved;
5, therapeutic outcome
Table 1 is treated pain Comparison of therapeutic
| Group | Treatment number | Recovery from illness | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 100 | 60 | 25 | 13 | 2 | 98％ |
6, conclusion
Three courses for the treatment of of pain patients (9 days each courses for the treatment of) such as treatment group treatment rheumatism of the present invention, rheumatoid arthritis, hyperosteogeny, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, traumatic injury, lumbar muscle strain, sciatic nerve, therapeutic outcome shows total effective rate 98%.
Experimental example two, model case
Case 1: grandson, man, 48 years old.Existing 4 years of left sufficient and left macLean-Maxwell disease.Pain degree is tired relevant with work, and there is pain history in the past, now fully recover, but left foot outside and calcaneus pain does not disappear all the time, and has dermal sensation outside shank to go down, and fails to respond to any medical treatment, and mental pressure is very large.Check: waist is without deformity, activity still can, but before while bending over, left lower extremity discomfort, after bend over normal.It is positive that straight lower limb is raised experiment, feels to go down in left foot outside, and calcaneus is without button pain or tenderness.Knee joint heel-tap reflex exists.X-ray photo shows degenerative lumbar, and left calcaneus is without extremely.CT scan is shown waist 5 sacrum 1 intervertebral disk hernia 7.5MM, outstanding to rear left.Diagnosis: prolapse of lumbar intervertebral disc; By taking capsule of the present invention (according to embodiment 1 method preparation) treatment two courses for the treatment of (take each 29 days each courses for the treatment of every day three times), patient's movable function of bending over obviously improves, shank sensory recovery.Continual cure recovers normal a course for the treatment of on inspection substantially.
Case 2: Liu, man, 54 years old.Main suit's head and neck rear portion, left side migraine more than 1 year.Wake up each morning and feel that left thumb fiber crops bitterly.Two upper limb are praised movable normal, but head turns to chronognosis left neck root in right side to have sense of dragging.Often there are at ordinary times the outbreaks such as dizzy, left ear tinnitus, blurred vision.Dare not by bike, once fall down because of dizzy.Weather seemingly has symptom to increase the weight of while transformation.Check: x-ray cervical vertebra photo shows that neck physiology lordosis disappears, 4-6 hyperosteogeny of cervical vertebra, neck 5-6 intervertebral is narrow, uncovertebral joint hyperosteogeny.Diagnosis: cervical spondylosis (vertebral artery type); By taking tablet of the present invention (according to embodiment 2 method preparations) treatment two courses for the treatment of (take each 29 days each courses for the treatment of every day three times), patient's migraine is obviously alleviated.Take again a course for the treatment of, patient recovers normal substantially on inspection.
Case 3: marquis, man, 32 years old, workman.Lumbago 3 years.Before 3 years in the time of aggravating activities lumbar strain, massage pain relief through doctor, after this recur lumbago because praising weight again.This time feel that waist is tired, ache because of fatigue, can not lie on the back, while bending over to bend, waist has fracture sense.Examine and see red tongue, thin fur, stringy pulse, psoas muscle anxiety, can touch pain spot, and x-ray film making checks no abnormal.Diagnosis: lumbar muscle strain; By taking (take each 1 bag 9 days each courses for the treatment of every day three times) remission after two courses for the treatment of of granule of the present invention (according to embodiment 3 methods preparations) treatment, readme has not affected work, continues to take 1 recovery from illness course for the treatment of.Follow up a case by regular visits to and do not recur again for 2 years.
Case 4: Lee so-and-so, female, 25 years old.Sprain left ankle joint because of rope skipping, swell and ache, night fever, erythrocyte sedimentation rate 35 millis m/h, to the eight at night aggravation of swelling and ache, extremities joint swells and ache, limitation of activity.Anemophobia is afraid of cold.Red tongue yellow and thin fur, stringy and thready pulse.Diagnosis: acute rheumatic arthritis; Method for the treatment of: clearing away heat and nourishing YIN, reducing swelling and alleviating pain, dispelling wind and removing obstruction in the collateral.Use emplastrum of the present invention (according to embodiment 4 method preparations), treat (9 days courses for the treatment of) after 2 courses for the treatment of.Pain subtracts greatly, can fall asleep, and swells and ache and only disappears, and body temperature is normal.Continue to use and consolidate curative effect 1 course for the treatment of.Observe not recurrence for many years.
Case 5: Zhang, female, 50 years old.There is the nearly articulations digitorum manus swelling of the right hand the 3rd, pain in the spring in 2008 without obvious inducement in patient, movable unfavorable, companion's deadlock in morning phenomenon, and next year is involved left knee joint, diagnosis and treatment in time.09 year spring, left knee joint symptom increased the weight of, and medical local special outpatient clinic, is diagnosed as " rheumatoid arthritis ", gives Radix Tripterygii Wilfordii medicated wine and Chinese herbal medicine etc., poor effect.Examine again in the People's Hospital of Beijing, take Caulis Fibraureae wine, Caulis Fibraureae sheet nearly half a year, the state of an illness is alleviated substantially.Afterwards because there is facial pigmentation, hyperhidrosis and the drug withdrawal of gastrointestinal upset symptom.Within 10 years, rise and gradually involve the closely extremity such as finger, metacarpophalangeal joints and two wrist, two ankle and right knee joint size joint of both hands, successively apply various medicines 2 years, the state of an illness not effectively control.Patient's active rheumatism aggravation, extremity size arthralgia, morning, stiff phenomenon was obvious, and appetite disappears simultaneously, skeletonize (body weight is down to only 30 kilograms by nearly 45 kilograms), so that bed, through multi-treatment, body constitution is recovered to some extent, but joint symptom does not subtract.Take the each joint of both hands, duplex, both shoulders joint etc., swollen hot pain is as outstanding, movable unfavorable, and spirit is poor, emaciated physique, and the flesh bone that withering, shortness of breath and fatigue, indigestion and loss of appetite lack of appetite, sleeps generally night, and two is just as usual.Analyze: arthromyodynia, damp and hot resistance network, QI and blood deficiency of both the liver and kidney.Treatment: wholistic therapy, take a tonic or nourishing food to build up one's health bone strengthening, soothing the channels and quicking the network vessels, YIN nourishing Liver and kidney, blood-activating analgetic.The application of the invention ointment (according to embodiment 5 method preparations) treatment two courses for the treatment of (9 days each courses for the treatment of), the each joint of both hands, duplex, the hot pain of both shoulders swollen joint are clearly better, and knee joint function obviously improves.Continue to use a course for the treatment of, patient can normally walk.Substantially, recover on inspection normal.
Following embodiment all can realize the effect of above-mentioned experimental example.
Specific implementation method
Embodiment 1 capsule
Add conventional adjuvant to make capsule according to common process said medicine, every day 3 times, each 2.
Embodiment 2 tablets
Add conventional adjuvant to make tablet according to common process said medicine.Every day 3 times, each 2.
Embodiment 3 granules
Said medicine is added to the agent of conventional adjuvant granulation according to common process.Every day 3 times, each 1 bag.
Embodiment 4 emplastrumes
Add conventional adjuvant to make emplastrum according to common process said medicine.
Embodiment 5 ointments
Add conventional adjuvant to make ointment according to common process said medicine.
Embodiment 6 sprays
Add conventional adjuvant to make spray according to common process said medicine.
Claims (7)
1. a pharmaceutical composition for the treatment of pain, is characterized in that, the crude drug of said composition consists of:
2. pharmaceutical composition as claimed in claim 1, is characterized in that, the crude drug of this pharmaceutical composition consists of:
3. pharmaceutical composition as claimed in claim 1, is characterized in that, the crude drug of this pharmaceutical composition consists of:
4. pharmaceutical composition as claimed in claim 1, is characterized in that, the crude drug of this pharmaceutical composition consists of:
5. the pharmaceutical composition as described in one of claim 1-4, is characterized in that this pharmaceutical composition adds conventional adjuvant to make the tablet of clinical acceptance, capsule, granule, pill, oral liquid, emplastrum, ointment, spray, liniment or tincture according to common process.
6. the application of the pharmaceutical composition as described in one of claim 1-4 in the medicine of preparation treatment pain.
7. the application of pharmaceutical composition as claimed in claim 6 in the medicine of preparation treatment pain, its feature refers in described pain the pain that rheumatism, rheumatoid arthritis, hyperosteogeny, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis, prolapse of lumbar intervertebral disc, traumatic injury, lumbar muscle strain, sciatic nerve etc. cause.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410022482.0A CN103784765A (en) | 2014-01-15 | 2014-01-15 | Pharmaceutical composition for treating pains |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410022482.0A CN103784765A (en) | 2014-01-15 | 2014-01-15 | Pharmaceutical composition for treating pains |
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| CN103784765A true CN103784765A (en) | 2014-05-14 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104069246A (en) * | 2014-07-16 | 2014-10-01 | 张湛 | Traditional Chinese medicine composition for treating ischialgia |
| CN104491492A (en) * | 2014-12-23 | 2015-04-08 | 李爱志 | Plaster for treating bone rheumatism and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1076120A (en) * | 1993-01-19 | 1993-09-15 | 王来运 | Medical liquid for relaxing tendons and joints |
| CN1250664A (en) * | 1999-09-07 | 2000-04-19 | 陶金山 | Chinese medicine for treating gout |
| CN1634517A (en) * | 2004-12-13 | 2005-07-06 | 张兴仕 | Medicine composition for treating lumbago, leg and arm pain and generalized pain, and preparation method thereof |
-
2014
- 2014-01-15 CN CN201410022482.0A patent/CN103784765A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1076120A (en) * | 1993-01-19 | 1993-09-15 | 王来运 | Medical liquid for relaxing tendons and joints |
| CN1250664A (en) * | 1999-09-07 | 2000-04-19 | 陶金山 | Chinese medicine for treating gout |
| CN1634517A (en) * | 2004-12-13 | 2005-07-06 | 张兴仕 | Medicine composition for treating lumbago, leg and arm pain and generalized pain, and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 姚血明等: "类风湿关节炎的中医药治疗进展", 《辽宁中医药大学学报》, vol. 11, no. 10, 31 October 2009 (2009-10-31), pages 191 - 193 * |
| 楚利涛: "骨痹内治方药组方用药规律的文献研究", 《中国优秀硕士学位论文全文数据库 医药卫生科技辑》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104069246A (en) * | 2014-07-16 | 2014-10-01 | 张湛 | Traditional Chinese medicine composition for treating ischialgia |
| CN104491492A (en) * | 2014-12-23 | 2015-04-08 | 李爱志 | Plaster for treating bone rheumatism and preparation method thereof |
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Application publication date: 20140514 |
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| RJ01 | Rejection of invention patent application after publication |