CN103784220B - Multipurpose adsorbable artificial vertebral plate - Google Patents
Multipurpose adsorbable artificial vertebral plate Download PDFInfo
- Publication number
- CN103784220B CN103784220B CN201410011501.XA CN201410011501A CN103784220B CN 103784220 B CN103784220 B CN 103784220B CN 201410011501 A CN201410011501 A CN 201410011501A CN 103784220 B CN103784220 B CN 103784220B
- Authority
- CN
- China
- Prior art keywords
- vertebral plate
- matrix
- plate body
- stator
- lower edge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Prostheses (AREA)
Abstract
The invention discloses a kind of multipurpose adsorbable artificial vertebral plate, comprise vertebral plate body, described vertebral plate body is by having the matrix of domes and being located at the outside stator of matrix both sides and inner side stator is formed, implantable autologous osteomiosis block above described matrix, the two ends of described matrix are respectively arranged with upper limb and lower edge, described upper limb and lower edge are respectively arc-shaped protrusions, the lower surface of described upper limb and the upper surface of described lower edge offer the first arc groove and the second arc groove respectively, second arc groove of the lower edge upper surface of lastblock vertebral plate body can be seamless spliced with the first arc groove of the upper limb lower surface of next block vertebral plate body, the side of the close matrix on described outside stator and inner side stator is symmetrically arranged with several sewing holes for sewing up respectively.Physical property of the present invention, mechanical strength are suitable, can be widely used on rear side of cervical vertebra, thoracic vertebra, lumbar vertebra, sacrum and coccyx, the reparation of the various Structural Faults of rear outside and outside.
Description
Technical field
The present invention relates to a kind of multipurpose adsorbable artificial vertebral plate.
Background technology
Laminectomy is the modus operandi that spinal surgery is relatively commonly used, and is often referred to by Via Posterior Spinal Approach cut-out or whole vertebral plate, exposes canalis spinalis and also clear up intraspinal pathological changes.But after vertebrae plate resection, the spinal column posterior column structure because of surgical disruption, cause corresponding spinal instability, and form scar tissue hypertrophy in Lamina defect district, with dura mater and adhesion of nerver root, involve, pressuring nerve vascular tissue etc., postsurgery symptoms is recurred, causes the postoperative failed syndrome (FBSS) of vertebra, have a strong impact on the long-term effect of spinal operation, how preventing the generation of this complication, is field of spinal surgery problem urgently to be resolved hurrily.
Artificial neural plate (artificiallamina, AL) be in human spine's vertebral plate, rear or posterolateral stucture excision or when to cause disappearance as reasons such as pathological changes because of other, can be used as to this excision or deleted areas carry out implanting repair time Shi ー kind artificial implant.Artificial neural plate is to postoperative the caused secondary scar adhesion of vertebrae plate resection, cause oppressing dural sac and nerve root and the unstable spine that causes has preventive effect, effectively dura mater and musculus sacrospinalis matsurface can be kept apart, can prevent opisthogenesis fibrous tissue from growing to intraspinal tube, scar tissue also can be prevented simultaneously to the compressing of dural sac and spinal cord.
Desirable artificial neural plate should meet the physiology and appearance 26S Proteasome Structure and Function anatomical features of human body vertebral plate, also should possess to functional bone directed differentiation alive and can for the benefit of area of new bone cell deposition and grow the ability provided support, the defect can repairing vertebral plate completely, Ginseng and surround canalis spinalis, protect dural sac from oppressing, avoiding adhesion, stabilizing spine, prevent the feature such as generation of the complication such as postoperative restenosis.
Mainly there is following shortcoming in the artificial neural plate adopted in prior art:
1, configuration is comparatively simple, can not provide good depositing support, be unfavorable for the growth of area of new bone for area of new bone cell.As Chinese invention patent ZL02275837.2 (authorized announcement date: 2003.6.25) Pi Lu ー kind artificial neural plate, this vertebral plate Shi ー cross section is arc curve form and has the matrix of axial length simultaneously, the cross section of the indent side at least in its arc curve form cross section is circular arc, the matrix of this artificial neural plate lacks support on each side, be unfavorable for the deposition of area of new bone cell, Post operation hematocele can not be made to discharge in time.Further, this artificial neural plate can not be used for repairing the little defect of canalis spinalis fenestration that causes of Minimally Invasive Surgery, can not be used for repairing the irregular defect of the spinal column sheet that the major operation such as severe trauma, tumor of spine causes.
2, to be divided into the ability of bone system cell poor for the artificial neural plate inducing target cell of prior art, is unfavorable for the growth of inducing new bone.
Summary of the invention
In order to the mechanical strength overcoming the existence of existing artificial neural plate is uncontrollable, be unfavorable for the shortcoming of inducing new bone growth etc., the invention provides a kind of mechanical strength suitable, be beneficial to the multipurpose adsorbable artificial vertebral plate of induction new bone proliferation, fusion.
The technical solution used in the present invention is:
Multipurpose adsorbable artificial vertebral plate, comprise vertebral plate body, it is characterized in that: described vertebral plate body is by having the matrix of domes and being located at the outside stator of matrix both sides and inner side stator is formed, implantable autologous osteomiosis block above described matrix, the two ends of described matrix are respectively arranged with upper limb and lower edge, described upper limb and lower edge are respectively arc-shaped protrusions, the lower surface of described upper limb and the upper surface of described lower edge offer the first arc groove and the second arc groove respectively, second arc groove of the upper surface of lastblock vertebral plate body lower edge can be seamless spliced with the first arc groove of the lower surface of next block vertebral plate body upper limb, the side of the close matrix on described inner side stator and outside stator is symmetrically arranged with several sewing holes for sewing up respectively.
Further, the inner surface of described inner side stator is provided with the first inclined-plane, the gradient on the first described inclined-plane and the shape of spinous process basilar part fixed connection place suitable.
Further, the outer surface of described outside stator is provided with the second inclined-plane, and the first inclined-plane on the gradient on the second described inclined-plane and the inner side stator of another block vertebral plate body is used in combination, and the side direction realizing two pieces of vertebral plate bodies by sewing hole connects.
Further, the diameter of described sewing hole is 1 ~ 1.5mm.
The monolithic of multipurpose adsorbable artificial vertebral plate of the present invention or polylith various combination, be widely used in the repairing of canalis spinalis wall defect in local after the various Wicresofts fenestration operation of approach or posterolateral approach on rear side of cervical vertebra, thoracic vertebra, lumbar vertebra, sacrum and coccyx, or do the postoperative repairing that vertebral plate cuts art (bilateral lamina and spinous process all excise) entirely in posterior approach operation, be even applicable to filling up of posterior cervical single open-door art, double door art or " Z " the shape postoperative local enabling side canalis spinalis wall of vertebral canal plastic operation.Can various irregular defective region be covered, rebuild the air-tight state of canalis spinalis, and keep the normal sagittal diameter of canalis spinalis and transverse diameter.
The front view of the matrix of artificial neural plate of the present invention can be rectangle or square, and its size can be:
Foursquare size:
10*10mm, 15*15mm, 20*20mm, 25*25mm, 30*30mm, 35*35mm, 40*40mm, by that analogy;
Rectangular size:
10*15mm, 10*20mm, 10*25mm, by that analogy;
15*20mm, 15*25mm, 15*30mm, by that analogy;
20*25mm, 20*30mm, 20*35mm, by that analogy;
25*30mm, 25*35mm, 25*40mm, by that analogy;
35*40mm, 35*45mm, 35*50mm, by that analogy.
Polylith artificial neural plate of the present invention is superimposed with each other splicing up and down, is applicable to the vertebral column canal wall defect of repairing various length.Both ensure that the seal of canalis spinalis, the autologous osteomiosis block preventing top from implanting falls into canalis spinalis, effectively stops that scar tissue climbs into canalis spinalis; Simultaneously when physical activity, the activities such as entirety can stretch along with vertebral body, rotation, simulate human body physiological state; And in motor process, upper lower edge is made rail mounted and is rotated in arc groove, makes to remain good covering state between upper and lower vertebral plate, ensure that the sealing state of canalis spinalis.
The side direction of two pieces of artificial neural plates connects, and outside intermediate portion, stator and the superimposed of inner side stator play intermediate transverse girder effect, not easily cave in after implanting autologous osteomiosis block up.The side direction of artificial neural plate connects the repairing of irregular defect while of being applicable to various vertebral column canal rear structure, posterolateral stucture or outside structure.
The present invention is after the osteomiosis block hypertrophy above vertebral plate, fusion, and the canalis spinalis form of reconstruction, effective sagittal diameter and transverse diameter, Effective spinal canal volume etc. are all close to normal physiological condition.
Artificial neural plate of the present invention makes area of new bone can grow fast according to both shaped of artificial neural plate; Simultaneously due to artificial neural plate material non-toxic, there is good biocompatibility, and the ability that this material inducing target cell is divided into bone system cell is comparatively strong, therefore is more beneficial to the growth of new bone.The artificial neural plate most Final of ， that in use degraded gradually is degradable and be absorbed by the body when new bone formation, has very high safety.
Beneficial effect of the present invention is embodied in:
1, physical property, mechanical strength, histocompatibility, the interior soak time completely of body etc. are all more satisfactory, do not have immunoreactivity, have antibacterial or viral communication risk;
2, the autologous broken bone block that artificial neural plate makes patient make full use of to obtain when reducing pressure in art after using carries out bone grafting process, rebuilds integrity and the stability of spinal column rear structure;
3, before mutually not merging at plant bone mass, forming new vertebral plate, artificial neural plate can provide enough large bracing force, does not allow plant bone mass subside, and prevents cicatrix from climbing into; And mutually merge at plant bone mass, after forming new, enough strong vertebral plate, oneself can dissolve, thoroughly absorb, do not stay foreign body, without any side effects to surrounding tissue cells;
4, enough mechanical strengths can be provided, ensure autologous bone graft fragment hypertrophy, fusion above it, again form complete bone canalis spinalis;
5, the outer scar hyperplasia of canalis spinalis, compressing, adhesion dural sac and nerve root can effectively be stopped;
6, after implanting, artificial neural plate can maintain completely effective mechanical strength 2-3 individual month, for the hypertrophy of autologous bone graft fragment, fusion provide time enough;
7, artificial neural plate finally can thoroughly absorb in vivo, and foreign remains;
8, artificial neural plate is splendid with the compatibility of adjacent tissue, cell in vivo, and without any side effects etc.
Accompanying drawing explanation
Fig. 1 is overall structure schematic diagram of the present invention.
Fig. 2 is side direction structural representation of the present invention.
Fig. 3 is B-B ' place of the present invention schematic cross-section.
Fig. 4 is A-A ' place of the present invention schematic cross-section.
Fig. 5 a is the upper and lower superimposed splicing schematic diagrams of the present invention's two pieces of artificial neural plates.
Fig. 5 b is the side view of the upper and lower superimposed splicing of the present invention's two pieces of artificial neural plates.
Fig. 6 is the using state schematic diagram of the present invention local fenestration operation.
Fig. 7 is the present invention's two pieces of vertebral plate side direction connection diagrams.
Fig. 8 is after the fenestration operation of local, and vertebral plate, rear structure segmental defect, artificial neural plate implants schematic diagram (the autologous osteomiosis block Hui Zhi cut in operation is above artificial neural plate).
Fig. 9 is the complete collyriculums such as laminectomy Post operation, bilateral lamina, spinous process, rear structure, and artificial neural plate implants schematic diagram (the autologous osteomiosis block Hui Zhi cut in operation is above artificial neural plate).
Figure 10 be on rear side of spinal column and outboard structure simultaneously irregular defect time, monolithic artificial neural plate repairs schematic diagram.
Figure 11 be on rear side of spinal column and outboard structure simultaneously irregular defect time, schematic diagram is repaired in the splicing of polylith artificial neural plate side.
Detailed description of the invention
Referring to figs. 1 through Fig. 9, artificial neural plate, comprise vertebral plate body, described vertebral plate body is by having the matrix 1 of domes and being located at the outside stator 2 of matrix 1 both sides and inner side stator 3 is formed, implantable autologous osteomiosis block above described matrix 1, the two ends of described matrix 1 are respectively arranged with upper limb and lower edge, described upper limb and lower edge are respectively arc-shaped protrusions 4, the lower surface of described upper limb and the upper surface of described lower edge offer the first arc groove 5 and the second arc groove 6 respectively, second arc groove 6 of the upper surface of lastblock vertebral plate body lower edge can be seamless spliced with the first arc groove 5 of the lower surface of next block vertebral plate body upper limb, the side of the close matrix 1 on described outside stator and inner side stator is symmetrically arranged with several sewing holes 7 for sewing up respectively.
Further, the inner surface of described inner side stator 3 is provided with the first inclined-plane 31, the gradient on the first described inclined-plane 31 and the shape of spinous process basilar part fixed connection place suitable.
Further, the outer surface of described outside stator 2 is provided with the second inclined-plane 21, the first inclined-plane 31 on the gradient on the second described inclined-plane 21 and the inner side stator 3 of another block vertebral plate body is used in combination, and the side direction realizing two pieces of vertebral plate bodies by sewing hole 7 connects.
Further, the diameter of described sewing hole 7 is 1 ~ 1.5mm.
The various combination of multipurpose adsorbable artificial vertebral plate monolithic of the present invention or polylith, be widely used in the repairing of local canalis spinalis wall defect after approach on rear side of cervical vertebra, thoracic vertebra, lumbar vertebra, sacrum and coccyx or posterolateral approach Wicresoft fenestration operation, or do the postoperative repairing that vertebral plate cuts art (bilateral lamina and spinous process all excise) entirely in posterior approach operation, be even applicable to filling up of posterior cervical single open-door art, double door art or " Z " the shape postoperative local enabling side canalis spinalis wall of vertebral canal plastic operation.Can various irregular defective region be covered, rebuild the air-tight state of canalis spinalis, and keep the normal sagittal diameter of canalis spinalis and transverse diameter.
Posterior lumbar spinal surgery as shown in Figure 8: after the fenestration operation of local, vertebral plate, rear structure segmental defect, carry out artificial neural plate implantation, repairing, and by the autologous osteomiosis block Hui Zhi that cuts in art above artificial neural plate.
Posterior lumbar spinal surgery as of fig. 9 shown: lumbar vertebra laminectomy Post operation, the complete collyriculums such as bilateral lamina, spinous process, rear structure, carry out artificial neural plate implantation, repairing, and by the autologous osteomiosis block Hui Zhi that cuts in art above artificial neural plate.
As shown in Figure 10, on rear side of spinal column and outboard structure simultaneously irregular defect, when defect is less, can directly repair with artificial neural plate monolithic, then in the bone grafting process of the autologous osteomiosis block of artificial neural plate outer row, the integrity of reconstruction vertebral column canal and sealing.
As shown in Figure 11, on rear side of spinal column and outboard structure simultaneously irregular defect, when defect is larger, the splicing of available artificial neural plate polylith side is repaired, then in the bone grafting process of the autologous osteomiosis block of artificial neural plate outer row, rebuilds integrity and the sealing of vertebral column canal.
In the present embodiment, the making material of artificial neural plate is Medical absorbable material, main employing natural biologic material and synthetic material two class.The former mainly uses the preparations such as collagen fiber, chitin (chitosan), oxidized cellulose.The latter mainly comprises polylactic acid, politef, silicone rubber etc.
Compared to above-mentioned bi-material, can adopt especially with recombination human serum albumin is the solid material that raw material is cross-linked synthesis, and recombination human serum albumin material has following advantage: 1. the hypoimmunity of people's source material; 2. virus-free infection risk; 3. controlled degradation speed; 4. adjustable mechanical strength; 5. splendid biocompatibility; 6. catabolite safety and nutritious repair tissue effect.
The making material of artificial neural plate in the present embodiment, also can adopt the biodegradable artificial synthesis bone of energy: nanocrystalline collagen-based bone renovating material especially.Nanocrystalline collagen-based bone renovating material is a kind of Bionics Bone, has good biocompatibility, without immunological rejection and cross infection disease may, and by osteoblast and osteoclast effect, new bone can be formed while degraded.
Content described in this description embodiment is only enumerating the way of realization of inventive concept; protection scope of the present invention should not be regarded as being only limitted to the concrete form that embodiment is stated, protection scope of the present invention also and conceive the equivalent technologies means that can expect according to the present invention in those skilled in the art.
Claims (2)
1. multipurpose adsorbable artificial vertebral plate, comprise vertebral plate body, it is characterized in that: described vertebral plate body is by having the matrix of domes and being located at the outside stator of matrix both sides and inner side stator is formed, implantable autologous osteomiosis block above described matrix, the two ends of described matrix are respectively arranged with upper limb and lower edge, described upper limb and lower edge are respectively arc-shaped protrusions, the lower surface of described upper limb and the upper surface of described lower edge offer the first arc groove and the second arc groove respectively, second arc groove of the upper surface of lastblock vertebral plate body lower edge can be seamless spliced with the first arc groove of the lower surface of next block vertebral plate body upper limb, the side of the close matrix on described inner side stator and outside stator is symmetrically arranged with several sewing holes for sewing up respectively,
The inner surface of described inner side stator is provided with the first inclined-plane, the gradient on the first described inclined-plane and the shape of spinous process basilar part fixed connection place suitable;
The outer surface of described outside stator is provided with the second inclined-plane, and the first inclined-plane on the gradient on the second described inclined-plane and the inner side stator of another block vertebral plate body is used in combination, and the side direction realizing two pieces of vertebral plate bodies by sewing hole connects.
2. artificial neural plate as claimed in claim 1, is characterized in that: the diameter of described sewing hole is 1 ~ 1.5mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410011501.XA CN103784220B (en) | 2014-01-10 | 2014-01-10 | Multipurpose adsorbable artificial vertebral plate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410011501.XA CN103784220B (en) | 2014-01-10 | 2014-01-10 | Multipurpose adsorbable artificial vertebral plate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103784220A CN103784220A (en) | 2014-05-14 |
| CN103784220B true CN103784220B (en) | 2016-04-06 |
Family
ID=50660576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410011501.XA Active CN103784220B (en) | 2014-01-10 | 2014-01-10 | Multipurpose adsorbable artificial vertebral plate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103784220B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107411854A (en) * | 2017-07-12 | 2017-12-01 | 中南大学湘雅医院 | A kind of practical artificial neural plate device |
| CN112155806B (en) * | 2020-10-23 | 2023-12-19 | 中国人民解放军空军军医大学 | Vertebral column posterior reconstruction device after laminectomy |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2315922Y (en) * | 1997-12-29 | 1999-04-28 | 汤继文 | Artificial bone vertebral lamina |
| CN2331328Y (en) * | 1998-05-26 | 1999-08-04 | 四川华神川大生物材料有限责任公司 | Titanium alloy compound artificial vertebral lamina with coating |
| CN2557104Y (en) * | 2002-07-24 | 2003-06-25 | 四川国纳科技有限公司 | Bionic artificial vertebral lamina |
| CN2880012Y (en) * | 2006-03-14 | 2007-03-21 | 杭州市萧山区中医院 | Artificial vertebral lamina |
| CN200948182Y (en) * | 2006-09-12 | 2007-09-19 | 于天彦 | Moveable manpower neural scute |
| CN202313814U (en) * | 2011-11-11 | 2012-07-11 | 康学文 | Artificial vertebral plate |
| CN203915149U (en) * | 2014-01-10 | 2014-11-05 | 陈哲 | Multipurpose adsorbable artificial vertebral plate |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6592625B2 (en) * | 1999-10-20 | 2003-07-15 | Anulex Technologies, Inc. | Spinal disc annulus reconstruction method and spinal disc annulus stent |
| US9480503B2 (en) * | 2002-01-03 | 2016-11-01 | Rohit Khanna | Universal laminoplasty implant |
-
2014
- 2014-01-10 CN CN201410011501.XA patent/CN103784220B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2315922Y (en) * | 1997-12-29 | 1999-04-28 | 汤继文 | Artificial bone vertebral lamina |
| CN2331328Y (en) * | 1998-05-26 | 1999-08-04 | 四川华神川大生物材料有限责任公司 | Titanium alloy compound artificial vertebral lamina with coating |
| CN2557104Y (en) * | 2002-07-24 | 2003-06-25 | 四川国纳科技有限公司 | Bionic artificial vertebral lamina |
| CN2880012Y (en) * | 2006-03-14 | 2007-03-21 | 杭州市萧山区中医院 | Artificial vertebral lamina |
| CN200948182Y (en) * | 2006-09-12 | 2007-09-19 | 于天彦 | Moveable manpower neural scute |
| CN202313814U (en) * | 2011-11-11 | 2012-07-11 | 康学文 | Artificial vertebral plate |
| CN203915149U (en) * | 2014-01-10 | 2014-11-05 | 陈哲 | Multipurpose adsorbable artificial vertebral plate |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103784220A (en) | 2014-05-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Dougherty et al. | The natural history of alloplastic implants in orbital floor reconstruction: an animal model | |
| Vuyk et al. | Biomaterials in rhinoplasty | |
| US9468521B2 (en) | Surgical methods for breast reconstruction or augmentation | |
| US20110076316A1 (en) | Scalable matrix for the in vivo cultivation of bone and cartilage | |
| JP2002516156A (en) | Implantable tissue repair device | |
| CN109481101B (en) | Anterior cervical self-fixing artificial vertebral body | |
| EP3630214A1 (en) | Resorbable crosslinked form stable membrane | |
| Grecchi et al. | Reconstruction of the zygomatic bone with smartbone®: Case report | |
| EP2726114B1 (en) | Flat self-curling permeable sheet membrane | |
| Ansari et al. | Grafts and implants in rhinoplasty—techniques and long-term results | |
| CN103784220B (en) | Multipurpose adsorbable artificial vertebral plate | |
| CN101999951B (en) | Memory alloy artificial cervical intervertebral disc | |
| CN203915149U (en) | Multipurpose adsorbable artificial vertebral plate | |
| US20120029643A1 (en) | Restorative device | |
| CN110123492A (en) | A kind of induction Bone Ingrowth spinal fusion system | |
| CN101889915B (en) | Artificial vertebral lamina | |
| CN202605057U (en) | Artificial vertebral lamina | |
| CN217548319U (en) | Self-locking artificial vertebral plate device for rear of vertebral body | |
| Yogishwarappa et al. | Customized osteomesh cranioplasty | |
| Hoell et al. | Total dura substitute in the spine: double layer dural substitute made from polylactide layer and bovine pericardium | |
| CN202526289U (en) | Resetting fixing device in single vertebral body of human body | |
| Oripov et al. | Current aspects of surgical repair for orbital wall fractures: a literature review | |
| CN206576988U (en) | A kind of plunger type porous support for eye socket bone defect healing | |
| RU2301642C1 (en) | Implant for resconstruction plasticization of wide defects | |
| Vamanshankar et al. | Reconstruction of skull base defects |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |