CN103784165A - Ultrasonic diagnosis device - Google Patents

Ultrasonic diagnosis device Download PDF

Info

Publication number
CN103784165A
CN103784165A CN201310532739.2A CN201310532739A CN103784165A CN 103784165 A CN103784165 A CN 103784165A CN 201310532739 A CN201310532739 A CN 201310532739A CN 103784165 A CN103784165 A CN 103784165A
Authority
CN
China
Prior art keywords
detector
light
ultrasonic transmission
optical detection
abnormal position
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201310532739.2A
Other languages
Chinese (zh)
Inventor
高山晓
浦野妙子
中西务
中村健二
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toshiba Corp
Original Assignee
Toshiba Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2013140968A external-priority patent/JP6144131B2/en
Application filed by Toshiba Corp filed Critical Toshiba Corp
Publication of CN103784165A publication Critical patent/CN103784165A/en
Pending legal-status Critical Current

Links

Images

Landscapes

  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

The invention is used for improving position guide of an ultrasonic detector in ultrasonic image photography by utilizing organism optical calculating. The embodiment relates to an ultrasonic diagnosis device comprising an ultrasonic detector, an optical detector, an image generating unit, a calculating unit, an assist information generating unit and an output unit. The optical detector includes a light irradiating portion and multiple light detecting portions. The light irradiating portion is configured, around an ultrasonic wave receiving and sending surface of the ultrasonic detector, on the central axis of the surface in the long edge direction, and irradiates light into a detected body from at least one position. Around the ultrasonic wave receiving and sending surface, the light detecting portions are configured in different positions with the central axis in the long edge direction of the ultrasonic wave receiving and sending surface being a symmetric axis. The calculating unit calculates, based on the light intensity detected by each light detecting portion, the position and size of an abnormal part, showing a prescribed optical absorption coefficient, in the detected body. The display unit displays an ultrasonic wave image showing the position and size of the abnormal part.

Description

Diagnostic ultrasound equipment
Technical field
Embodiments of the present invention relate to diagnostic ultrasound equipment.
Background technology
The technology that organism inside is measured on non-intrusion type ground has various maneuvers.Photometry measuring tool as one of them has the following advantages: do not exist by the problem of radiation, and can be by selecting wavelength to select the compound as instrumentation object.With regard to general organism light measuring device, illumination part is overlayed on organism skin surface, percutaneously irradiate the light that instrumentation transmission or reflection come transmission skin and to the light after in vitro outgoing, calculate various Biont informations based on it again to organism inside.As survey to judge that portion exists the basic of abnormal structure in vivo by photometry, there are the different this point of absorptance of comparing light from normal structure.That is, the absorptance of abnormal structure of portion is different in vivo, therefore, can produce with the difference of absorbtivity and detect accordingly the poor of light quantity.In other words, solve if be used as Reverse Problem according to detection light quantity, can obtain the absorptance of abnormal structure, can distinguish according to the absorptance of obtaining the character of abnormal structure.In addition, by the light measuring, instrumentation position, the degree of depth are resolved.This parsing maneuver comprises: the maneuver (spatial decomposition method) of adjusting the distance of illumination part (later economizing slightly light source) and detector; The time dependent light source of working strength, the difference of time arriving according to light obtain the maneuver (time decomposition method) of depth information; And combine method of above-mentioned maneuver etc.By these analytic methods, realize the organism light measuring device of the signal that can obtain high-quality.But, the low problem of Existential Space resolution in the image conversion of the information of carrying out at the light by organism.And, in order to obtain correct positional information and need to carry out computing to mass data with complicated algorithm according to catoptrical testing result, and cannot judge in real time.
In organism photometry is surveyed, as realizing the application that probability is high, can list breast carcinoma inspection.But in the situation that carrying out photometry survey separately as described above, resolution and parsing time existing problems, therefore preferably with other treatment equipment (modality) and be used for improving inspection performance.So, the mode of utilizing the shape information of ultrasonic echo to compensate the low spatial resolution of light has been proposed in this application.By which, expect compared with the pastly can pick out morphological characteristic in bio-tissue and the component distributing of morphological characteristic part is distinguished with shorter time, but in the instant leeway being still improved in judging.
But breast carcinoma is one of major causes of death of women.The examination of breast carcinoma and early diagnosis have very great value for the expense that reduces mortality rate, inhibition health control.In present method, carry out breast tissue touch diagnosis and for finding out the X-ray of suspicious metaplasia.If there is suspicious position in X-ray photographs, carries out ultrasound wave photography, and then carry out the tissue examination of surgery.This series of inspection needs to spend considerable time till reaching final conclusion.In addition, the young layer mammary gland before amenorrhea is a lot, also has and in X-ray, is difficult to obtain highly sensitive problem.Therefore,, particularly for young layer, the meaning of the examination under ultrasound wave photography is very large.
Generally speaking, in ultrasound wave photography, obtain ultrasound wave rest image by obtaining the operator who assert, read sheet person's (being multiple sometimes) makes a determination according to the shape information on image by special.In view of existing due to operator's fatigue in diagnosis and concentration power is low and the examination of being undertaken by an operator is defined as maximum 50 of every day by the danger of over sight (OS) checking.
In the photography of ultrasonography, while obtaining the rest image that has captured morphological characteristic, operator's knowledge and experience is very important.Carry out accurately and examination rapidly, also require proficiency.For example each person under inspection's review time study plot says to be 5 to assign to 10 points, but sometimes needs to spend the more time because of operator's technical ability difference., present photographing by ultrasound wave in the examination of carrying out, according to operator's proficiency difference and the accuracy of Image Acquisition may have deviation.And, in the time obtaining image, both needed always watching attentively image, need again to rely on the independent judgement of operator, therefore, even if skilled operator, the burden of spiritual aspect is also very large.Also there is the mode of obtaining all images information with dynamic image, but in this situation also, it is large that the burden of the person's side of readding sheet becomes.
Draw the problem under layer diagnosis in order to solve such ultrasound wave, the metabolic information that proposed the organism by being recorded by organism photometry guides in face direction locating of ultrasonic detector, thereby alleviates the mode of technician's burden.By such mode, in ultrasonography photography, can be compared with the past with shorter time and more easily abnormal position is detected, distinguished.
Look-ahead technique document
Patent documentation
Patent documentation 1: JP 2004-073559 communique
Patent documentation 2: JP 2009-247683 communique
Patent documentation 3: JP 2000-237196 communique
Patent documentation 4: JP 2005-331292 communique
Patent documentation 5: JP 2007-020735 communique
Patent documentation 6: JP 2009-077931 communique
But, utilize organism photometry to survey the ultrasonic detector location guide of the ultrasonography photography of carrying out, still there is room for improvement.
Summary of the invention
The related diagnostic ultrasound equipment of present embodiment has ultrasonic detector, photo-detector, image generation unit, computing unit, computing unit, display unit.Ultrasonic detector sends ultrasound wave from ultrasonic transmission/reception towards subject, is received in via ultrasonic transmission/reception face the ultrasound wave being reflected in subject.Photo-detector has: illumination part, around ultrasonic transmission/reception face, is configured on the central shaft of long side direction of ultrasonic transmission/reception face, from least one position to subject internal radiation light; With multiple optical detection parts, around ultrasonic transmission/reception face, take the central shaft of the long side direction of ultrasonic transmission/reception face as axis of symmetry is configured in diverse location, detect the light intensity being reflected in subject.Image generation unit uses the ultrasound wave being received by ultrasonic detector to generate ultrasonography.The light intensity that computing unit detects based on each optical detection part, calculating illustrates abnormal portion bit position and the size of the absorption coefficient of light of regulation in subject.Display unit shows the ultrasonography that abnormal portion bit position and size are expressed.
Accompanying drawing explanation
Fig. 1 is the figure that represents the mount structure figure of the related diagnostic ultrasound equipment of the first embodiment 1.
Fig. 2 is the mount structure figure that is surveyed the organism light measuring device 4 that processing unit 42 forms by photo-detector 40, photometry.
Fig. 3 is illumination part 400 and the optical detection part 401a～d figure with respect to the configuration example of ultrasonic detector 12.
Fig. 4 (a) and (b), (c) are the figure for the mensuration processing that uses the degree of being close to that the configuration example of Fig. 3 carries out is described.
Fig. 5 (a) and (b), (c) are the figure for the three-dimensional orientation at specification exception position and the mensuration processing of distance.
Fig. 6 is the figure that is illustrated in the configuration example of illumination part 400 that the three-dimensional orientation at abnormal position and the mensuration of distance uses in processing and optical detection part 401a～d.
Fig. 7 is an example of having measured in breast carcinoma inspection to being presented at the support information on monitor 14 the three-dimensional orientation at the degree of being close to of breast, abnormal position and distance.
Fig. 8 is the variation of the support information of demonstration on monitor 14.
Fig. 9 is the figure representing for abnormal position being configured in to an example of the support information that the one-step boot in ultrasonic scanning region is object.
Figure 10 is for moving the figure of an example of the support information that to make from the maximized secondary boot of semaphore of the light at abnormal position after ultrasonic detector 12 be object according to one-step boot.
Figure 11 be using the signal intensity of the detection light based on each optical detection part 401 absorption signal intensity that calculate, each optical detection part 401 (or deamplification intensity) as support information, the embodiment showing with level instrument.
Figure 12 (a) and (b) are the figure that represent an example of the support information of exporting as audible signal.
Figure 13 is the variation of the configuration shown in Fig. 6.
Figure 14 is other variation of the configuration shown in Fig. 6.
Figure 15 is other variation of the configuration shown in Fig. 6.
Figure 16 is other variation of the configuration shown in Fig. 6.
Figure 17 is other variation of the configuration shown in Fig. 6.
Figure 18 is other variation of the configuration shown in Fig. 6.
Figure 19 is the mount structure figure of the organism light measuring device 4 that has of the related diagnostic ultrasound equipment of the second embodiment 1.
Figure 20 is the mount structure figure of the organism light measuring device 4 that has of the related diagnostic ultrasound equipment 1 of the 3rd embodiment.
Figure 21 has represented to use degree of being close to that the organism light measuring device 4 shown in Figure 20 carries out to judge and the figure of an example of the order that the orientation at abnormal position determines.
Figure 22 is the mount structure figure of the organism light measuring device 4 that has of the related diagnostic ultrasound equipment 1 of the 4th embodiment.
Figure 23 is the figure that observes the detector of the related diagnostic ultrasound equipment 1 of the 5th present embodiment from subject contact surface side.
Figure 24 is schematically illustrated in abnormal position to be approximately in the situation of spheroid, the figure of detector P and the abnormal portion bit position of determining on ultrasonic scanning cross section and size.
Figure 25 is the figure that represents the ultrasonography corresponding with ultrasonic scanning cross section.
Figure 26 is the figure of the demonstration form for the abnormal position of having determined position and size on ultrasonography is described.
Figure 27 is the figure that represents the variation 1 of configuration detector, illumination part 400 and optical detection part 401 of the related diagnostic ultrasound equipment 1 of the 5th embodiment.
Figure 28 is the figure that represents the variation 2 of configuration detector, illumination part 400 and optical detection part 401 of the related diagnostic ultrasound equipment 1 of the 5th embodiment.
Figure 29 is the figure that represents the variation 3 of configuration detector, illumination part 400 and optical detection part 401 of the related diagnostic ultrasound equipment 1 of the 5th embodiment.
Figure 30 represents to be surveyed the abnormal position determined and the state that approaches of detector by organism photometry, the figure of the form such as, representing as the lightness (variation) of the part (icon etc.) of the picture of ultrasonography.
Figure 31 (a)～(d) is that example is along with detector and the abnormal position of determining approach and the figure of the sample state that the lightness of icon changes.
Figure 32 (a)～(d) is example along with detector and the abnormal position of determining approach and the figure of the sample state that the color of icon etc. change.
Figure 33 (a)～(d) is that example is along with detector and the abnormal position of determining approach and the figure of the sample state that the display area of icon changes.
Figure 34 (a)～(d) is that example is along with detector and the abnormal position of determining approach and the figure of the sample state that the display position of icon changes.
Figure 35 (a)～(d) is example along with detector and the abnormal position of determining approach and the figure of the sample state of the amplitude variations of the swing of icon.
Figure 36 (a)～(d) is example along with detector and the abnormal position of determining approach and the figure of the sample state of the change of shape of icon.
The explanation of Reference numeral
1 ... diagnostic ultrasound equipment, 11 ... apparatus main body, 12 ... ultrasonic detector, 13 ... input equipment, 14 ... monitor, 21 ... ultrasound wave transmitting element, 22 ... ultrasound wave receiving element, 23 ... B mode treatment unit, 24 ... doppler processing unit, 25 ... RAW data storage, 26 ... volume data generation unit, 28 ... graphics processing unit, 30 ... display processing unit, 31 ... control processor (CPU), 32 ... memory element, 33 ... interface unit, 40 ... photo-detector, 42 ... photometry is surveyed processing unit, 44 ... support information generating unit, 400 ... illumination part, 401 ... optical detection part, 420 ... light source 420, 422 ... optical signal control part, 424 ... light analysis unit, 426 ... computing circuit
The specific embodiment
Below, with reference to the accompanying drawings each embodiment is described.In addition, in the following description, give same reference numerals to the element with roughly the same function and structure, repeat specification is only just carried out in the case of necessary.
(the first embodiment)
Fig. 1 shows the mount structure figure of the related diagnostic ultrasound equipment of present embodiment 1.Diagnostic ultrasound equipment 1 shown in this figure possesses: ultrasonic detector 12, input equipment 13, monitor 14, ultrasound wave transmitting element 21, ultrasound wave receiving element 22, B mode treatment unit 23, doppler processing unit 24, RAW data storage 25, volume data generation unit 26, graphics processing unit 28, display processing unit 30, control processor (CPU) 31, memory element 32, interface unit 33.In addition, the related diagnostic ultrasound equipment 1 of present embodiment also possesses: survey processing unit 42 for photo-detector 40 and the photometry of realizing organism light measuring device 4; And generation is used for the support information generating unit 44 of the support information that the configuration operation of ultrasonic detector 12 is supported.
In addition, in present embodiment, as shown in Figure 1, the diagnostic ultrasound equipment 1 that is built-in with organism light measuring device (with the integral structure of organism light measuring device) is described as an example.But, be not limited to this example, also organism light measuring device and diagnostic ultrasound equipment can be made as to split structure.
Ultrasonic detector 12 is that the subject take organism as typical case is sent to ultrasound wave, and receive ultrasound wave based on this transmission and from the equipment (probe) of the echo of subject reflection, have at its front end: be arranged with multiple piezoelectric vibrators, matching layer, cushion member etc.The driving signal of piezoelectric vibrator based on from ultrasound wave transmitting element 21, the required direction in scanning area sends ultrasound wave, and the echo from this subject is transformed to the signal of telecommunication.Matching layer is arranged at this piezoelectric vibrator, is the intermediate layer for ultrasonic energy is propagated efficiently.Cushion member prevents that ultrasound wave from rearward propagating from this piezoelectric vibrator.If send ultrasound wave from this ultrasonic detector 12 to subject, this transmission ultrasound wave is constantly reflected by the discontinuity surface of the acoustic impedance of in-vivo tissue, is received by ultrasonic detector 12 as echo-signal.The amplitude of this echo-signal depends on acoustic impedance poor of the discontinuity surface that has carried out reflection.In addition, the echo in the situation of the blood flow reflection during the ultrasonic pulse sending is moved, according to Doppler effect, depends on the speed composition of the ultrasonic transmission/reception sense of moving body, is subject to frequency shift (FS).
In addition, in present embodiment, being made as ultrasonic detector 12 is the one-dimensional array detectors that are arranged with multiple ultrasonic oscillators along the direction of regulation.But, be not limited to this example, ultrasonic detector 12 is as the structure that can obtain volume data, can be also two-dimensional array detector (multiple ultrasonic oscillators are arranged in the detector of two-dimensional-matrix-like) or mechanical type 4D detector (when can making ultrasonic oscillator be listed in mechanically to strafe in the direction orthogonal with its orientation, carrying out the detector of ultrasonic scanning).
Input equipment 13 is connected with apparatus main body 11, such as has, by the various switches in the capture apparatus main bodys 11 such as the setting indication in the various indications from operator, condition and care region (ROI), various image quality condition setting indication, button, tracking ball, mouse, keyboard etc.In addition, input equipment 13 has the button etc. of indicating the timing of the paracentesis information of obtaining the tip position that comprises puncture needle for support function in paracentesis described later.
The video signal of monitor 14 based on from display processing unit 30, is shown as image by the morphologic information in organism or blood flow information.
Ultrasound wave transmitting element 21 has not shown triggering for generating circuit, delay circuit and impulse circuit etc.In triggering for generating circuit, with the speed frequency f rHz(cycle stipulating; 1/fr second) repeatedly produce to be used to form and send hyperacoustic trigger impulse.In addition, in delay circuit, each trigger impulse is given for ultrasound wave boundling fasciculation and decision being sent to directivity and the time delay of needs according to each channel.Impulse circuit, in the timing based on this trigger impulse, applies driving pulse to detector 12.
Ultrasound wave receiving element 22 has not shown amplifying circuit, A/D changer, delay circuit, adder etc.In amplifying circuit, the echo-signal of obtaining via detector 12 is amplified according to each channel.In A/D changer, the echo-signal of the simulation after amplifying is transformed to digital echo signal.In delay circuit, echo-signal after digital conversion is determined to receive directivity, and give and will receive dynamic focusing needed time delay, then in adder, carry out addition process.By this addition, make to be emphasized from the reflex components of the direction corresponding with the reception directivity of echo-signal, by receiving directivity and send directivity the comprehensive bundle that forms ultrasonic transmission/reception signal.
Echo-signal is accepted from receiving element 22 in B mode treatment unit 23, implements logarithmic amplification, envelope detection processing etc., generates the data that show signal intensity with the lightness of brightness.
Doppler processing unit 24 extracts blood flow signal from the echo-signal receiving from receiving element 22, generates blood flow data.The extraction of blood flow is conventionally by CFM(Color Flow Mapping: color blood-stream) carry out.In this situation, blood flow signal is resolved, as blood flow data, obtain the blood flow informations such as average speed, dispersion, energy for multiple points.
RAW data storage 25 uses the multiple B mode datas that receive from B mode treatment unit 23, the B pattern RAW data as B mode data on the ultrasonic scanning line of generating three-dimensional.In addition, RAW data storage 25 uses the multiple blood flow data that receive from doppler processing unit 24, the blood flow RAW data as blood flow data on the ultrasonic scanning line of generating three-dimensional.In addition, in order to realize the reinforcement of noise decrease and image relatedness, also can after RAW data storage 25, insert three-dimensional wave filter, carry out the smoothing processing in space.
The RAW-voxel conversion that volume data generation unit 26 comprises by execution the interpolation processing that the positional information in space is taken into account, generates B pattern volume data, blood flow volume data.
Graphics processing unit 28, to the volume data of accepting from volume data generation unit 26, carries out the image processing of the regulations such as volume drawing, multi-section conversion demonstration (MPR:multi planar reconstruction), maximum Projection Display (MIP:Maximum intensity projection).In addition, in order to realize the increase of relatedness of noise decrease and image, also can after graphics processing unit 28, insert two-dimentional wave filter, carry out the smoothing processing in space.
Display processing unit 30, to generation, various view data after treatment in graphics processing unit 28, is carried out the various processing such as dynamic range, brightness (brightness), contrast, gamma curve correction, RGB conversion.
Control processor 31 has the function as information processor (computer), controls the action of each element.In addition, control processor 31 is carried out the processing that is dependent on ultrasonic detector operation assisting function described later.
Memory element 32 keepings are useful on and realize the dedicated program of ultrasonic detector operation assisting function described later, volume data, diagnostic message (patient ID, doctor's opinion etc.), diagnosing protocol, receiving and transmitting signal condition, other data groups that photography is arrived.In addition, as required, be also used to the keeping of the image in not shown image storage etc.The data of memory element 32 also can be via interface unit 33 by external peripheral device transmission.
Interface unit 33 is interfaces relevant with input equipment 13, network, new external memory (not shown).In addition, can also, via interface unit 33, incite somebody to action, the organism light measuring device of peripheral hardware is connected in this diagnostic ultrasound equipment main body 11.Can by data or the analysis results etc. such as the ultrasonography being obtained by this device by interface unit 33 via network to other device transmit.
Fig. 2 is the mount structure figure that is surveyed the organism light measuring device 4 that processing unit 42 forms by photo-detector 40, photometry.
Photo-detector 40 has at least one illumination part 400 and multiple optical detection part 401.The light (near infrared light) that illumination part 400 produces light source 420 irradiates towards subject.Optical detection part 401 has the detection faces being for example made up of the end of optical fiber, by forming via the multiple detecting elements that carry out light-to-current inversion from the reflected light in subject of optical guided wave portion input from this detection faces.As detecting element, except such as can adopting the photo detector such as photodiode, phototransistor, can also adopt CCD, APD, photomultipliers etc.Also can light matching layer be set at the contact surface contacting with subject of illumination part 400 and each optical detection part 401.
Fig. 3 represents illumination part 400 and the optical detection part 401a～d figure with respect to the configuration example of ultrasonic detector 12.Near the central authorities of the ultrasonic transmission/reception face 120 at ultrasonic detector 12 shown in this figure, configure illumination part 400, and, on the circumference centered by illumination part 400, with the contact surface that ultrasonic transmission/reception face 120(is contacted with subject) mode in being enclosed in, the example that optical detection part 401a～d is uniformly-spaced configured.The contact surface with subject contact of illumination part 400 and each optical detection part 401a～d is for example set the height level identical with ultrasonic transmission/reception face 120 for, is configured to the state contacting directly or indirectly with subject surface in the time of instrumentation.In addition, illumination part 400 and optical detection part 401 are not limited to the example shown in Fig. 3 with respect to the configuration of ultrasonic detector 12.About the application examples of configuration, wait until below and describe in detail.
Photometry is surveyed processing unit 42 and is had light source 420, optical signal control part 422, light analysis unit 424, computing circuit 426.Light source 420 is the light-emitting components such as semiconductor laser, light emitting diode, solid state laser, gas laser etc. that produce following light, this light is: (for example in organism, absorb the light of little wavelength, being known as near the wavelength band of window of organism is the light of 600nm～1800nm scope), the light of the specific wavelength that increases in abnormal position absorbtivity (for example, being called as the light of the wave-length coverage of 750～850nm that the hemoglobin within the scope of the wavelength band of window of organism and in blood absorbs).The optical guided wave portion (or direct propagation via space) that the light producing in light source 420 forms via optical fiber or by film light guided wave road, is supplied with to illumination part 400.In addition, light source 420 also can form integratedly with illumination part 400.
Optical signal control part 422 dynamically or is statically controlled organism light measuring device 4.For example, optical signal control part 422, under the control of the control processor 31 of diagnostic ultrasound equipment 1, is controlled light source 420, and the timing that makes to stipulate, frequency, intensity, intensity variable cycle T, from illumination part 400 light irradiations.In addition, optical signal control part 422 is controlled light analysis unit 424, makes to carry out light dissection process in the timing of regulation.
Light analysis unit 424 is transformed to digital signal the analogue signal of inputting from optical detection part 401 is amplified.And light analysis unit 424 changes and resolves the detection light intensity of 401 of optical detection parts.
The detection light intensity of computing circuit 426 based on 401 of optical detection parts changes, three-dimensional position and the distance at the abnormal position of calculating optical detection part 401 and the degree of being close on subject surface, for example, such as, be benchmark with the abnormal position (, absorbing more the position of specific wavelength than normal structure) of the absorption coefficient of light and the surface degree of depth apart of subject, the position of regulation (illumination part 400, ultrasonic transmission/reception Mian120 center etc.) that regulation is shown in subject.Result of calculation in computing circuit 426 is sent to supports information generating unit 44.
(ultrasonic detector operation assisting function)
Next the ultrasonic detector operation assisting function, this diagnostic ultrasound equipment being had describes.This function refers to, at least one party in three-dimensional orientation and the distance (nearness) at the abnormal position in degree of being close to and the subject on calculating ultrasonic detector 12 and subject surface, based on its result, generate and export for guide better the position of ultrasonic detector 12, support information towards, posture, pressurization degree etc. with respect to subject and diagnosis object position, to ultrasonic detector, operation is supported thus.
(the mensuration processing of degree of being close to)
First, optical detection part 401 and the mensuration processing of the degree of being close on subject surface are described.At this, what is called degree of being close to is about the thickness of the air layer existing in the gap between optical detection part 401 and organism surface and occupies the amount of the sectional area ratio of light path.What ideal was talked about is there is no air layer, or thickness is for detection light wavelength is following and coverage rate is below 0.1%.
Fig. 4 (a) and (b), (c) are the figure for the mensuration processing that uses the degree of being close to that the configuration example of Fig. 3 carries out is described.In addition, Fig. 4 (a) and (b), (c) separately in, at the A-A of epimere presentation graphs 3 sectional view, represent that at hypomere each detection faces of shadow surface, optical detection part 401 of illumination part 400 is to the projection of subject surface projection.
As shown in Figure 4 (a), first, detector P is being configured under the lip-deep state of subject, from illumination part 400 towards subject internal radiation near infrared light.Now, be assumed to following situation: optical detection part 401b～d(corresponds respectively to ch2～4) detection faces contact well with subject surface, and at optical detection part 401a(corresponding to ch1) detection faces and subject surface between Existential Space (gap).In this case, in the optical detection part 401a leaving with respect to subject surface, due to the difference of refractive index, and make the detected face reflection of a catoptrical part of emitting from subject.As its result, to the incident intensity of optical detection part 401a than the incident illumination to optical detection part 401b～d a little less than.The variation of the light intensity that such optical detection part is 401 in light analysis unit 424 resolved out.Computing circuit 426 is by the signal level of the light intensity in optical detection part 401a, and the numerical value calculating with named peril minus exception rate with the signal level of predefined light intensity or according to the signal level of the light intensity in optical detection part 401b～d, compares.As its result, the signal level of the light intensity in optical detection part 401a is less, computing circuit 426 is judged to be optical detection part 401a and leaves (the low state of degree of being close to) with respect to subject surface.In the time that whole optical detection part 401 is judged as suitable degree of being close to, it is proper range that the degree of being close to of the ultrasonic detector 12 being surrounded by optical detection part 401 is also judged as.
Support result of determination and the result of calculation of information generating unit 44 based on computing circuit 42, generate position to ultrasonic detector 12, posture, towards etc. the support information indicating, guide, to ultrasonic transmission/reception face 120 and subject are close to.The support information generating form with regulation on monitor 14 is shown.In addition, about the concrete example of the information of support, wait until below and describe in detail.
Operator operates ultrasonic detector 12 according to the guiding of shown support information, and degree of being close to is measured again.As its result, fall into the moment in appropriate scope being judged to be degree of being close to, start ultrasonography photography.
(the abnormal three-dimensional orientation at position and the mensuration processing of distance)
Next, the mensuration processing of the three-dimensional orientation to abnormal position and distance describes.Fig. 5 (a) and (b), (c) are the figure for the three-dimensional orientation at specification exception position and the mensuration processing of distance.Fig. 6 is the figure that is illustrated in the configuration example of illumination part 400 that the three-dimensional orientation at abnormal position and the mensuration of distance uses in processing and optical detection part 401a～d.In addition, Fig. 5 (a) and (b), (c) separately in, using abnormal position as absorber, and show respectively the A-A sectional view of Fig. 6 at epimere, show each detection faces of illumination part 400, optical detection part 401 to the projection on subject surface at hypomere.
First, in order to calculate three-dimensional orientation and the distance at abnormal position, detector P is being configured under the lip-deep state of subject to the light of the specific wavelength that can increase in abnormal position absorbtivity towards subject internal radiation from illumination part 400.Optical detection part 401a '～401d ' in locating with illumination part 400 closer locations (approximated position) as shown in Fig. 5 (a) and the light that detects respectively this irradiation in the optical detection part 401a～401d locating compared with distant positions (circumferential position) with illumination part 400 as shown in Fig. 5 (b) are from the reflected light in subject.
Incident illumination one side in vivo scattering is passed through on one side, if but will be absorbed more by abnormal position.Therefore the detection light that, is configured in the optical detection part (in the example of Fig. 5, Fig. 6 for test section 401a, optical detection part 401a ') of specific range becomes the depth information that includes abnormal position.Light analysis unit 424 is to corresponding respectively to ch1～4 from being configured in each azimuthal optical detection part 401a～401d(), the detection light of optical detection part 401a '～401d ' (corresponding respectively to ch5～8) resolves.Result, for example in Fig. 5 (a) ch2 < ch1 < ch3, ch4, in Fig. 5 (b) ch5,6 < ch7, known 8 in the situation that, at (between ch5 and ch6) between ch2 and ch1 and near ch2(ch5) position of side has abnormal position.In addition,, according to known a little less than the signal intensity of signal intensity ratio ch2, the ch1 of for example ch5, ch6, abnormal position is present in superficial position.
The signal intensity profile of computing circuit 426 to the approximated position parsing and the signal intensity profile of circumferential position compare, as shown in Fig. 5 (c), calculate for example, three-dimensional direction and distance for the reference position (illumination part 400) at existing abnormal position.Specifically, light intensity signal in the normal structure of obtaining utilizing the function of the distance between illumination part 400 and optical detection part 401 is as reference value, so according to the reference value in 1 optical detection part 401 by the reference value standardization of the optical detection part of other positions 401.Coefficient using the reference value after standardization as the light intensity of the position of each optical detection part 401, obtain the light intensity signal of being surveyed out by each optical detection part 401 and the difference of light intensity reference value, calculate the ratio of difference and light intensity reference value and set it as rate of change, calculate the azimuth at abnormal position and approach state according to rate of change and positional information.And, X coordinate and the rate of change of each optical detection part 401 are multiplied each other, the result after multiplying each other is obtained to worthwhile or meansigma methods and be used as directions X composition.Also similarly obtain Y-direction composition, Z direction composition.Obtain the deflection of the direction vector that the each composition obtaining as its result is synthesized into, generate thus the azimuth (azimuth information) at abnormal position.And, by X coordinate, rate of change, the multiplication of each optical detection part 401 and obtain absolute value, these are carried out to the worthwhile X composition that is used as.Similarly obtain Y-direction composition, Z direction composition.Use the value absolute value of all directions being added up to and obtain, calculate the three-dimensional distance take the illumination part 400 at abnormal position as benchmark.
Support information generating unit 44 for abnormal position is configured in ultrasonic scanning region, and three-dimensional orientation based on obtained, three-dimensional distance generate the support information for the movement of ultrasonic detector 12 is indicated, guided.The support information generating form with regulation in monitor 14 is shown.In addition, about the concrete example of the information of support, wait until below and explain.
Operator, according to the guiding of shown support information, moves ultrasonic detector 12, again carries out the three-dimensional orientation at abnormal position and the mensuration of distance.Be judged to be the moment that abnormal position has fallen in appropriate scope (for example, being judged to be abnormal position and having fallen the central authorities in ultrasonic scanning region) as its result, start ultrasonography photography.
(support information)
Fig. 7 is an example of measuring in breast carcinoma inspection to being shown in the support information of monitor 14 the three-dimensional orientation at the degree of being close to of breast, abnormal position and distance.In the example of this figure, with deep or light ultrasonic transmission/reception face 120 degree of being close to breast surface that show of image, for example, in picture, bottom right represent the low region of signal intensity comparatively speaking compared with dark-part.In addition, the supposition Depth display at the abnormal position on this figure right side is that zero position represents, the low reason of intensity is surface.Known according to two demonstrations, enlighten the region lower at signal intensity, detector has floated from organism surface.Operator, according to the guiding of shown support information, in order to make to become the lightness identical with other regions compared with dark-part, and presses the operation of the lower right side of detector strongly.
Fig. 8 is the variation that is shown in the support information of monitor 14, and the detector degree of being close to based on calculating shows detection defective work with cross mark.In the example of this figure, cross mark concentrates on picture bottom right, therefore known, and the detection faces of the optical detection part 401 corresponding with this cross and the degree of being close on subject surface are lower.Operator's visuognosis, to this shown support information, according to its guiding, is pressed the operation of the lower right side of detector, strongly to improve the degree of being close to that detects defective work.
According to the support information shown in Fig. 7 or Fig. 8, ultrasonic detector 12 is operated, after detector 12 and the degree of being close on subject surface have fallen in proper range, provide the azimuth information at abnormal position and for configure more well moving direction, the amount of movement of ultrasonic detector 12 with respect to this abnormal position, as support information.
Fig. 9 is the figure representing for abnormal position being configured in to an example of the support information that the one-step boot in ultrasonic scanning region is object.By ultrasonic detector 12 is moved according to the direction of arrow shown in this figure and distance (length of arrow), operator can be easily configured in abnormal position in ultrasonic scanning region.Figure 10 be represent take make according to one-step boot ultrasonic detector 12 moved after for making the figure of the maximized secondary boot of semaphore from the light at abnormal position (in the case of multiple optical detection parts 401 detect from the light at abnormal position as this semaphore and) as an example of the support information of object.By this secondary boot, ultrasonic detector 12 is moved, to semaphore is maximized by the degree of depth at abnormal position.By carrying out so interim guiding, compared with the past, can obtain more signal from abnormal position.
Figure 11 is absorption signal intensity that calculate, each optical detection part 401 (or deamplification intensity) by the signal intensity of the detection light based on each optical detection part 401, is shown in the embodiment of level instrument (level meter) as support information.In the figure, known according to the balance of signal intensity, abnormal position is present near light source.
Fig. 7～11 example the support information that moving direction and the amount of movement etc. of the degree of being close to detector, ultrasonic detector are represented, situation about exporting by image on monitor 14.On the other hand, also can export support information by audible signal.
Figure 12 (a) and (b) show an example of the support information being output as audible signal.In the example of Figure 12 (a), by optical detection part 401(or ultrasonic transmission/reception face) current degree of being close to, with the periodicity of sound, notice to operator.For example, be judged as the aphonia state for epimere in non-contacting situation at whole optical detection parts 401, be determined at least one optical detection part 40 interrupted tone of exporting stage casing in non-contacting situation, be determined degree of being close to and export suitable in the situation that the continuant of hypomere at whole optical detection parts 401.In addition,, in the example of Figure 12 (b), notify the information that approaches at abnormal position with the height of sound (frequency).For example, along with detector approaches abnormal position, make the continuant exported with the cycle shown in the epimere of Figure 12 (b), low frequency as shown in Figure 12 (b).The support information based on audible signal like this, has advantages of that operator does not observe monitor 14 and can accept scanning guiding yet.In addition, be not limited to this example, for example, also can, by controlling volume, tuning, rhythm, melody, sound etc., support information be exported as audible signal.
(configuration variation)
Next, illumination part 400 and optical detection part 401 variation with respect to the configuration of ultrasonic detector 12 is described.
Figure 13 is the variation of the configuration shown in Fig. 6.In the variation shown in this figure, at the upper configuration of central shaft (axis of symmetry) the illumination part 400(of the long side direction of ultrasonic transmission/reception face 120 light source), by multiple optical detection parts 401, to become radial with respect to light source and to become the mode of line symmetry with respect to the central shaft of ultrasonic detector 120, be configured on double concentric circular.By making like this arrangement axis of symmetry of optical detection part 401 and the central shaft of ultrasonic detector 12 consistent in fact (or the configuration axis of symmetry that makes optical detection part 401 drops in the scope of plant width of ultrasonic detector), can eliminate the relative site error of two kinds of detection systems, so, than Fig. 6, configuration aspect is better.In addition, illumination part 400 is needed as the more than 2 times of the degree of depth measured at abnormal position to the ultimate range of optical detection part 401, so have as detector P entirety the trend that becomes large.But, by illumination part 400 being configured in to the approximated position place on the central shaft of ultrasonic detector 12 as this variation, compared with the example of Fig. 6, can realize the size reduction of detector P entirety.
Figure 14 is other variation of the configuration shown in Fig. 6.In the variation shown in this figure, optical detection part 401 is with mode balanced configuration longer in the axial direction at ultrasonic detector 12.By this configuration, can suppress the width of detector P entirety, so strafing of ultrasonic detector 12 moved easily.
Figure 15 is other variation of the configuration shown in Fig. 6.In the variation shown in this figure, at the multiple illumination parts 400 of both sides of the chest balanced configuration of ultrasonic detector 12.In addition, multiple light is detected and is configured to, become radial and become line symmetry with respect to the central shaft of ultrasonic detector 12 with respect to the center of multiple light sources.By making photometry examining system consistent with the axle of ultrasonic detector 12, can eliminate the relative site error of two kinds of detection systems, so this embodiment is than the example of Fig. 6, configuration is convenient better.In addition, by using multiple illumination parts 400 and the selection of multiple optical detection parts 401 to detect, the distance from light source is in fact increased, there is the location that can detect by single light source abnormal position with broad range.
Figure 16 is other variation of the configuration shown in Fig. 6.In the variation shown in this figure, at the multiple illumination parts 400 of both sides of the chest balanced configuration of ultrasonic detector 12, in addition also on the central shaft of ultrasonic detector 12, configure other illumination part 400.In addition, multiple optical detection parts 401 are configured to become radial and become line symmetry with respect to the central shaft of ultrasonic detector 12 with respect to the center of multiple light sources.This distortion also, makes photometry examining system consistent with the axle of ultrasonic detector 12, thus, can eliminate the relative site error of two kinds of detection systems, so than the embodiment of Fig. 6, configuration aspect is better.In addition,, by using multiple light sources, there is the location of more detecting to broad range abnormal position.In addition, change the structure of the output light wavelength of the other light sources on multiple light sources of detector both sides of the chest and the central shaft of ultrasonic detector 12 by employing, can also obtain more information simultaneously.
Figure 17 is other variation of the configuration shown in Fig. 6.In the variation shown in this figure, by example in multiple ultrasonic detector 12(Figure 17 2) so that the mode arranged in series of central shaft alignment, at least one illumination part 400 of the center configuration of gap betwixt.This distortion also, makes photometry examining system consistent with the axle of ultrasonic detector 12, can eliminate the relative site error of two kinds of detection systems, so than the embodiment of Fig. 6, configuration aspect is good.In addition,, by making illumination part 400 be positioned at the arrangement center of multiple ultrasonic detectors 12, there is the existence exploration territory that can detect to broad range abnormal position.
Figure 18 is other variation of the configuration shown in Fig. 6.In the variation shown in this figure, be configured to make optical detection part 401 intensive in the final guide position vicinity at abnormal position.This distortion also, makes photometry examining system consistent with the axle of ultrasonic detector 12, has eliminated the relative site error of two kinds of detection systems, so than the embodiment of Fig. 6, configuration aspect is better.In addition,, by intensive configuration optical detection part 401 partly, there is the light absorption information that can spatially detect more accurately abnormal position.
In above-described each example, example by multiple optical detection parts 401 situation with the configuration of two concentric circles.But, be not limited to this each example, can be also on plural concentric circular, to arrange optical detection part 401.
The diagnostic ultrasound equipment related according to above-described present embodiment, can realize following effect.
The first, about the effect of the degree of being close on optical detection part and subject surface.,, in organism photometry is surveyed, under the state of not being close to subject at optical detection part, can produce reflection loss in the detection faces (light in part) of optical detection part, the losses that likely can produce 10% grade at most.And the caused difference of absorption at the abnormal position stage such as be % is on the other hand larger thereby above-mentioned optical detection part arranges the difference of bad caused signal.Therefore, can expect, whether the degree of being close to of optical detection part and organism is suitably the information that should confirm before the detection at abnormal position.According to this diagnostic ultrasound equipment, carry out the degree of being close on calculating detector and subject surface with organism photometry brake, generate support information the output for detector being directed to better position based on its result.Operator grasps the current contact condition on detector and subject surface, and is being close in incomplete situation, can be according to supporting the guiding of information, easily and promptly the posture to detector, proofread and correct towards, compression aspect, moving direction etc.
The second, about the effect of effective utilization of the depth information at abnormal position.Compared with the abnormal position that near the abnormal position existing skin surface and the depth at several centimetres (cm) exist, be different from the relative position obtaining between the detector of peak signal.Except the degree of depth at abnormal position is carried out orientation calculating, also should suitably carry out location guide.The diagnostic ultrasound equipment related according to present embodiment, calculate three-dimensional orientation and the distance at the abnormal position in subject with organism photometry brake, based on its result, so that abnormal position is configured in the mode of the good position in ultrasonic scanning region, generate support information output for the position of ultrasonic detector is guided.Operator can grasp current ultrasonic detector and abnormal portion bit position relation intuitively, and, in the situation that abnormal position is not present in ultrasonic scanning region, can be according to the guiding of the information of support, so that abnormal position is comprised in the mode in ultrasonic scanning region, easily and promptly the position to ultrasonic detector, posture, towards etc. proofread and correct.
The 3rd, the effect about ultrasonic detector with the para-position (aligning) of Systems for optical inspection.In the present embodiment, ultrasonic detector, at least one illumination part, multiple optical detection part are configured to make the axis of symmetry of illumination part, multiple optical detection parts to be positioned at ultrasonic transmission/reception face.As a result, can correct in the optimum position being directed to by the signal resolution of optical system and in the delicate error of observing the generation of picture position place by ultrasonic echo.
As previously discussed, unattended operation person's experience etc. are how, can both be under the state that ultrasonic transmission/reception face and subject surface are close to well, obtain all the time the good ultrasonography at abnormal position, and contribute to improve the quality of ultrasonography diagnosis.
(the second embodiment)
Figure 19 is the mount structure figure of the organism light measuring device 4 that has of the related diagnostic ultrasound equipment of the second embodiment 1.In the related diagnostic ultrasound equipment 1 of present embodiment, light source 420 produces the light of the specific wavelength that abnormal position absorbs, definite by calculating, the three-dimensional orientation at abnormal position etc. of this light degree of being close to.In addition, in computing circuit 426, be taken into ultrasonography from ultrasound wave camera chain, for example, the abnormal portion bit position in ultrasonic scanning area image is inferred in the variation of the brightness value based on ultrasonography, by utilizing this to infer the position, carry out the precision of the raising of positional precision in the survey of organism photometry and the abnormity at position and identify.By like this and with organism photometry examining system and ultrasound wave camera chain, the determining of the three-dimensional orientation at the more correctly calculating of degree of being close to, abnormal position etc.
(the 3rd embodiment)
Figure 20 is the mount structure figure of the organism light measuring device 4 that has of the related diagnostic ultrasound equipment 1 of the 3rd embodiment.Organism light measuring device 4 shown in this figure possesses: these two light sources of light source 420a and light source 420b, and light source 420a produces the absorption at abnormal position compared with the higher wavelength light of transmittance little and subject, and light source 420b produces the special wavelength light that abnormal position absorbs; With optical mixer 421, the light of two light sources is mixed.In this structure, by wavelength that relatively relatively the transmittance of subject is higher and the detection light quantity of specific wavelength, the effect of the absorption that can cause by the degree of being close to because of optical detection part 401 with because of abnormal position separately.And the detection light quantity of the wavelength by utilizing transmission subject is carried out standardization to the detection light quantity of specific wavelength, can reduce the evaluated error causing because of ultrasonic detector 12 and degree of the being close to deviation of subject.
In addition, organism light measuring device 4 shown in Figure 20 has computing circuit 426a, 426b, for example, in the time of guiding ultrasonic detector 12, in computing circuit 426a, carry out the definite Simple Calculation in orientation at degree of being close to, abnormal position, and on the other hand, in the time of abnormal evaluation, in computing circuit 426b, carry out the definite precision in orientation at degree of being close to, abnormal position and calculate.But, have enough computational speed and operational capability at computing circuit 426a or computing circuit 426b, also can guide ultrasonic detector 12 with the computing circuit of any one party.
Figure 21 represents that the degree of being close to carrying out with the organism light measuring device 4 shown in Figure 20 is judged and an example of the order that the orientation at abnormal position determines.As shown in the drawing, emit alternately the specific wavelength that wavelength that the transmittance of subject is higher and abnormal position absorb in from illumination part 400 to organism.As recorded above, the optical detection part 401 leaving from subject surface, a part for the flashlight of emitting from subject due to the difference of refractive index at surface reflection, thereby weaken the incident intensity to detector.
So, as shown in Figure 21 (a), in the case of first use the transmittance of subject compared with high wavelength, with the comparison of predefined light intensity signal level and measured signal intensity less, the optical detection part 401 that is judged to be this position leaves from subject surface.Generate support information showing based on degree of being close to result of determination, carry out thus indication, guiding for detector entirety is exerted pressure to the direction of being close to subject.As its result, as shown in Figure 21 (b), optical detection part 401 is adjusted to the pressurization on subject surface.
Then,, as shown in Figure 21 (c), the specific wavelength absorbing to the abnormal position of incident in organism, detects emitted light by each optical detection part 401.With regard to the rate of change of the detection light quantity that causes because of degree of being close to, the specific wavelength absorbing in the case of the higher wavelength of the transmittance of organism and at abnormal position, be all equal, both difference is very little.The significant difference of the detection light quantity of 2 wavelength results from having or not of abnormal position.Therefore, utilize after the light of the wavelength that the transmittance of organism is higher carries out standardization in the light quantity of the specific wavelength that abnormal position is absorbed, utilize the maneuver identical with the first embodiment, obtain three-dimensional orientation and the distance at the abnormal position in subject, generating direction information and range information.Generate support information and show based on azimuth information and range information, thus, moving direction and the compression aspect of ultrasonic detector 12 entirety being indicated, guided.As a result, be judged to be the moment of measurement detector position in proper range, starting ultrasonography photography.
(the 4th embodiment)
Figure 22 is the mount structure figure of the organism light measuring device 4 that has of the related diagnostic ultrasound equipment 1 of the 4th embodiment.Organism light measuring device 4 shown in this figure, on the basis of the example shown in Figure 20, is taken into the ultrasonography of being obtained by ultrasound wave photography in optical computing as data, can realize the precision of the raising of positional precision and the abnormity at position and identify.In the present embodiment, complete in the following order mensuration: the linking and calculate of the guiding of the detector relevant with degree of being close to, photography to the guiding of the ultrasonic detector 12 at abnormal position, ultrasonography, precision optics mensuration, ultrasonography and optical data, correcting image form.In addition, in the example shown in Figure 22, in the guiding of ultrasonic detector 12, be conventionally used as the computing circuit 426a of Simple Calculation circuit, but in the situation that signal intensity is higher, also can select to calculate the computing circuit 426b with computing circuit as precision.
In above-described each embodiment, illustrate by manual operation and carried out the survey of organism photometry.On the other hand, also can carry out the survey of organism photometry by automatic operation.
(the 5th embodiment)
The related diagnostic ultrasound equipment 1 of the 5th embodiment can more promptly calculate abnormal portion bit position, the size in subject, and can on ultrasonography, show clearly.
Figure 23 is the figure detector of the related diagnostic ultrasound equipment 1 of present embodiment being observed from subject contact surface side, is the figure that represents the configuration example of illumination part 400 and optical detection part 401.As shown in the drawing, illumination part 400, around ultrasonic transmission/reception face 120, is arranged in C on the central shaft of long side direction of this ultrasonic transmission/reception face 120.In the present embodiment, illumination part 400 simultaneously or optionally the light of 2 wavelength is irradiated to subject.Multiple optical detection parts 401, around ultrasonic transmission/reception face 120, are arranged as axis of symmetry radial mode in pairs and centered by illumination part 400 according to the central shaft C of the long side direction of the ultrasonic transmission/reception face take same.In addition, in the example of this figure, multiple optical detection parts 401 are at the radius r 1 centered by illumination part 400, such as r1=15mm of r2, r3(, r2=25mm, r3=35mm etc.) concentric circumference on, become axisymmetric mode to arrange the optical detection part 401 of (3 groups) with respect to C on central shaft with 3.In addition, illumination part 400 and each optical detection part 401 are covered by dark slide 403.
In addition, the arrangement of illumination part 400, multiple optical detection part 401 is not limited to the example of Figure 23, can adopt various forms.; the detector of the related diagnostic ultrasound equipment 1 of present embodiment drops on the structure in the scope of plant width (or width of the short side direction of ultrasonic transmission/reception face 120) of ultrasonic echo detector as long as the configuration axis of symmetry of the consistent in fact structure of axis of symmetry (plane of symmetry) that ultrasonic scanning face is arranged with multiple optical detection parts 401 or optical sensor, can be any.
In addition, the related organism light measuring device 4 of present embodiment also possesses storage for determining abnormal portion bit position in ultrasonic scanning cross section and big or small data base's memory element.This memory element can be both that internal storage can be also external memory storage, but from wanting to accelerate requirement and the needed memory span of processing, the embodiment that the semiconductor memory in use device carrys out keeping is preferred.About other structures, with identical on the content shown in Figure 20,22.Data base is the absorptance (k) according to each optics, and by abnormal portion bit position and size in the ultrasonic scanning face of ultrasonic detector 12, corresponding data base has been set up in each combination of the light intensity detecting with each optical detection part 401 in advance.Computing circuit 426a, 426b carry out, for by the actual light intensity detecting of each optical detection part 401 and the calculating that numerical value pre-stored in data base contrasts, determining abnormal portion bit position and size in ultrasonic scanning face.
The illumination part 400 configuring like that from Figure 23, the light (near for example, the light of 2 wavelength of the absorbing wavelength (900nm) of near the absorbing wavelength of oxygenated haemoglobin (770nm) and deoxyhemoglobin) of two specific wavelengths higher and that increase in abnormal position absorbtivity to detection bodies internal radiation organism absorbance.The light irradiating is propagated on one side in subject inscattering on one side, if absorbed more by abnormal position.Multiple optical detection parts 401 that Figure 23 configures like that detect the light from subject outgoing in position separately.The light that each optical detection part 401 detects includes the depth information at abnormal position.The light that light analysis unit 424 detects each optical detection part 401 is resolved.Computing circuit 426a, the 426b detection light intensity based on 401 of optical detection parts changes, and calculates degree of being close to, the abnormal portion bit position that the absorption coefficient of light of regulation is shown in subject, the size (size) on optical detection part 401 and subject surface.
Computing circuit 426a, 426b are according to the algorithm of having narrated, changing based on the detection light intensity of 401 of optical detection parts, the degree of depth apart of degree of being close to, the abnormal position of the absorption coefficient of light that regulation is shown in subject and the surface of subject of calculating optical detection part 401 and subject surface, is three-dimensional position and the distance at the abnormal position of benchmark take the position that stipulates.Result of calculation in computing circuit 426 is sent to supports in information generating unit 44.Support information generating unit 44 according to the maneuver of having narrated, generate position to ultrasonic detector 12, posture, towards etc. indicate, guide the support information of (navigation).The support information generating form with regulation in monitor 14 is for example shown.Operator, according to shown support information, moves ultrasonic detector 120 so that ultrasonic transmission/reception face 120 come the absorption coefficient of light that regulation is shown abnormal position directly over.In addition, about for make ultrasonic transmission/reception face 120 move to abnormal position directly over the demonstration form of support information, there are all kinds.To this, wait until in the 6th embodiment and explain.
On subject surface so that ultrasonic transmission/reception face 120 come the absorption coefficient of light that regulation is shown abnormal position directly over the mode of (or abnormal position is positioned on the plane of symmetry under the long limit axis of symmetry of ultrasonic detector 12), configure ultrasonic detector 120.If as its result, the position of ultrasonic detector 12 is judged as proper range, by next described such maneuver, execute exception portion bit position and big or small calculating.
Figure 24 is in the situation that abnormal position is approximately to spheroid, the abnormal portion bit position and the big or small figure that schematically represent detector P and determine on ultrasonic scanning cross section.By the center (x of spheroid, y), the level of the absorptance (k) of size (diameter phi), optics is as parameter, using light diffusion equation as direct problem (forward problem) and in the displace analysis light intensity of each photodetector, using making this solution and light absorption information set up corresponding data as data base, pre-stored in the memory element of organism light measuring device 4.In the case of by photo-absorption region with simplification spherical carry out approximate, can solve with the approximate solution of the distortion Bessel function of analytics, still, in the case of more complicated shape, be difficult to analyticity and solve.So, utilize the light diffusion equation simulation with scattering that has used Finite element method, obtain approximation.Data base can suitably select the level of parameter to calculate, and makes form based on this.At this, as the manufacture method of the form of light intensity and example simulation, but, also has following method: make the body mould (phantom) after the level of each parameter is gathered, decide the method for numerical value by practical measurement, and by a part for practical measurement data and analog result compound in conjunction with and make method.Therefore,, the in the situation that of spheric approximation, the unknown number that solve is these 4 of the absorptances (k) of position (x, y) on the picture of the cross section of organism, diameter (φ), optics, 4 actinometry results of minimum needs.In the situation that ellipsoid of revolution is approximate, 5 actinometry results of minimum needs.At this, paired detector is symmetrical on optical model, and light intensity should become equal value, so, will not detect data as independent values.
Computing circuit 426a, 426b contrast pre-recorded numerical value in above-mentioned data base and the light intensity detecting in each optical detection part 401.Means as a comparison, for example, have the system of selection of least square FAXIA.In this situation, the light intensity of each detector location changes according to figure place, so, need to use and utilize the light intensity of the situation that there is no light absorption position to carry out the standardization relative intensity variation after standardization etc., need to spend corresponding time.Data base's numerical value can calculate according to the time below second instantaneously with the contrast of the light intensity detecting.Therefore, can grasp in real time the information of the absorptance (k) of abnormal absorbent portion bit position (x, y), diameter (φ), optics.
; in the present embodiment; not to use the light intensity detecting in each optical detection part 401 to be used as inverse problem (reference the first embodiment etc.) to calculate abnormal portion bit position and size in subject; but use pre-stored data base in memory element and in each optical detection part 401 the actual light intensity detecting, be used as direct problem and calculate abnormal portion bit position and the size in subject.Such calculating maneuver for example, in the situation such as real-time is very important, has practical significance especially.But, be not limited to this example, certainly also can adopt the algorithm as inverse problem illustrating in the first embodiment etc.In addition, as required, can be also to prepare from the light of other wavelength of subject transmission, using this light as carrying out sensing with reference to light and by the mensuration light quantity standardization of other wavelength, reducing thus the evaluated error causing because of various deviations.
The abnormal portion bit position, the size that calculate are shown in real time with the form of regulation on ultrasonography.Figure 25 is the figure that represents the ultrasonography corresponding with ultrasonic scanning cross section, and Figure 26 is the figure of the demonstration form for the abnormal position that on ultrasonography position, size determined is described.On the ultrasonography shown in Figure 25, if calculate abnormal portion bit position, size, for example as shown in Figure 26, by distributing to the color of absorptance (k) of optics, show the circle of determined position (center (x, y)) and size (footpath φ).Thus, observer can grasp in real time and intuitively Position Approximate, the size at abnormal position on ultrasonography.In addition, show the ultrasonography at abnormal position by record, can be carried out diagnostic imaging by the ultrasonography of reflectionization with abnormal position is inevitable.
(variation 1)
Figure 27 is the figure detector of the related diagnostic ultrasound equipment 1 of present embodiment being observed from subject contact surface side, shows the figure of the variation 1 of the configuration of illumination part 400 and optical detection part 401.Illumination part 400 is arranged in C on the central shaft of long side direction of ultrasonic transmission/reception face 120, irradiates the light of (be not two wavelength but) specific wavelength.In addition 4 the optical detection part 401 of (4 groups) is arranged take the central shaft C of the long side direction of ultrasonic transmission/reception face as axis of symmetry.Thus, do not use the light of two wavelength, and can obtain the information of the absorptance (k) of abnormal portion bit position and size, optics.
(variation 2)
Figure 28 is the figure detector of the related diagnostic ultrasound equipment 1 of present embodiment being observed from subject contact surface side, shows the figure of the variation 2 of the configuration of illumination part 400 and optical detection part 401.As shown in the figure, two illumination part 400 diverse location places of C on the central shaft of the long side direction of ultrasonic transmission/reception face 120 are adjacent to configuration.In addition two (two groups) optical detection part 401 is arranged take the central shaft C of the long side direction of ultrasonic transmission/reception face as axis of symmetry.By this variation, do not use the light of two wavelength yet, and can obtain the information of the absorptance (k) of abnormal portion bit position and size, optics.In addition,, compared with the example shown in Figure 23, Figure 25, there is the quantity that can further reduce optical detection part 401.
(variation 3)
Figure 29 is the figure detector of the related diagnostic ultrasound equipment 1 of present embodiment being observed from subject contact surface side, is the figure that represents the variation 3 of the configuration of illumination part 400 and optical detection part 401.As shown in Figure, two illumination parts 400 are on the central shaft of the long side direction of ultrasonic transmission/reception face 120 on C, to configure across the mode of ultrasonic transmission/reception face 120.In addition two (two groups) optical detection part 401 is arranged take the central shaft C of the long side direction of ultrasonic transmission/reception face as axis of symmetry.By this variation, do not use the light of two wavelength yet, and can obtain the information of the absorptance (k) of abnormal portion bit position and size, optics.In addition, identical with variation 2, compared with the example shown in Figure 23, Figure 25, also there is the quantity that can further reduce optical detection part 401.And, by illumination part 400 being configured in to the two ends of ultrasonic detector 12, also have advantages of near the central authorities of C on the central shaft that easily abnormal position is directed to ultrasonic transmission/reception face 120.
According to structure as described above, detector can be guided (navigation) to be comprised under the state in scanning cross-section in this suspect tissue to the top of the suspect tissue of subject inside, implement the obtaining of ultrasonography, organism photometry is surveyed.Therefore, can use the light detecting, by the position of suspect tissue, size, as to the light intensity detecting in each test section with the direct problem that compares of data base generating in advance, easy and promptly calculate, can improve significantly real-time.Executing patient can carry out to observation and the optimum pernicious judgement etc. of plasma metabolism information clearly illustrating on the visual examination on the cross section of the detector configuration directly over the suspect tissue in subject, ultrasonography, this ultrasonography (information such as the absorption position of hemoglobin, size, absorptance) etc. with the high real-time of sequential.As its result, no matter proficiency how, who can correctly, suitably and promptly carry out breast carcinoma inspection judgement (detection, the optimum and pernicious judgement at abnormal position) etc.
In addition, in organism photometry is surveyed, the ultimate range from illumination part to optical detection part is required it is the more than 2 times of the degree of depth measured at abnormal position, so, have as detector entirety the trend that becomes large.In the present embodiment, be configured to the central shaft as the long side direction of ultrasonic transmission/reception face, illumination part and optical detection part are configured in near of ultrasonic detector, therefore, can make the overall dimensions of the detector that ultrasonic detector, photo-detector become one become small compact.
(the 6th embodiment)
In each embodiment of having narrated, the transfer means as detector to the degree of being close to of the guiding at abnormal position or good detector, example the such as explicit representation shown in Fig. 7～Figure 10 or method of transmitting by the audible signal shown in Figure 12 etc. etc.But in the time that reality is photographed, examiner observes ultrasonography while makes detector moving, so, also watch attentively simultaneously Fig. 7 wait shown in the support information of such detector operation, become sometimes very large burden.In addition, the transmission of carrying out based on audible signal has advantages of that examiner need not observe picture and just can accept scanning guiding, and also having but then examinee can become uneasy shortcoming because of abnormal sound.
So, in the present embodiment, following diagnostic ultrasound equipment 1 is described: survey the detector the determined information to the state that approaches at abnormal position by representing by organism photometry, to reduce examiner's the form of watching burden attentively as far as possible, promptly show in observable mode, make detector become easy to the guiding at abnormal position.
Expression detector in present embodiment in the demonstration form of the support information of the information of the state that approaches at abnormal position, detector operation, for example, has two following features.The first, a part for the picture of the ultrasonography of watching attentively as examiner, shows and represents the information of detector to the state that approaches at abnormal position.Thus, examiner does not make sight line back and forth just can obtain information.The second, can not hinder examiner to focus onto the degree of the behavior on ultrasonic diagnosis image, can grasp instantaneously the form of its content, show and represent the information of detector to the state that approaches at abnormal position.
Figure 30 shows and will be surveyed the abnormal position determined and the state that approaches of detector by organism photometry, the figure of the form such as, representing as a part (icon etc.) for the picture of ultrasonography.Figure 31 (a)～(d) has been example along with detector and the abnormal position of determining approach and the figure of the sample state that the lightness of icon changes.
The lightness of the icon A showing in the picture upper right of the ultrasonography shown in Figure 30 is as shown in Figure 31 (a) and (b), along with detector and the abnormal position of determining approach and change, at detector during close to abnormal position (, ultrasonic transmission/reception face 120 be configured in abnormal position directly over time), as shown in Figure 31 (c), the brightest.In addition, at ultrasonic transmission/reception face 120, from having left directly over abnormal position, the change of state of the lightness of icon A from the state of Figure 31 (c) to Figure 31 (d), along with detector leaves from abnormal position and dimmed gradually.
(variation 1)
Figure 32 (a)～(d) has been example along with detector and the abnormal position of determining approach and the figure of the sample state that the color of icon etc. change.
For example, the color of the icon A showing in the picture upper right of the ultrasonography shown in Figure 32 is being surveyed by organism photometry the abnormal position determined and the distance of detector be certain above, as shown in Figure 33 (a), for example, be shown with the form and aspect (green) that stipulate.If according to support information, scan detector, in the distance of abnormal position and detector becomes necessarily, the color of icon A is as shown in Figure 33 (b), be changed to other form and aspect (for example orange),, as shown in Figure 33 (c), for example, shown by redness during close to abnormal position at detector.In addition, at ultrasonic transmission/reception face 120 from having left directly over abnormal position, and the distance between abnormal position and detector accordingly, the lightness of icon A is changed to other colors (being green the example of Figure 33 (d)) from the redness of Figure 33 (c).
(variation 2)
Also can the variation in the light on and off cycle that approaches the part that state representation is the picture of ultrasonography (icon etc.) of the abnormal position determined and detector will be surveyed by organism photometry.For example, the icon A that the picture upper right of ultrasonography shows in the case of is surveyed by organism photometry the abnormal position determined and the distance of detector be certain more than, carry out light on and off with above long period necessarily.According to representing that detector is to the information of the state that approaches at abnormal position, scan detector, along with the distance of abnormal position and detector diminishes, and the light on and off cycle of icon A shortens, and at detector during close to position extremely, icon A carries out light on and off with the short period.In addition, at ultrasonic transmission/reception face 120, from having left directly over abnormal position, the distance between icon A and abnormal position and detector makes accordingly the cycle change while carries out light on and off.
(variation 3)
Figure 33 (a)～(d) has been example along with detector and the abnormal position of determining approach and the figure of the sample state that the display area of icon changes.
For example, the area of the icon A showing in the picture upper right of the ultrasonography shown in Figure 30 is as shown in Figure 33 (a), Figure 33 (b), become near and become large along with surveyed the distance of the abnormal position determined and detector by organism photometry, when close to abnormal position, as shown in Figure 33 (c), become maximum.In addition, at ultrasonic transmission/reception face 120, from having left directly over abnormal position, the area of icon A is as shown in Figure 33 (c), Figure 33 (d), along with detector leaves and diminishes from abnormal position.
(variation 4)
Figure 34 (a)～(d) is that example is along with detector and the abnormal position of determining approach and the figure of the sample state that the display position of icon changes.
For example, shown in for example Figure 34 of icon A (a), the Figure 34 (b) showing in the picture upper right of the ultrasonography shown in Figure 30, in the case of surveyed by organism photometry the abnormal position of determining separated with the distance of detector certain more than, be presented at identical position, when close to abnormal position (distance of abnormal position and detector become in certain limit), as shown in Figure 34 (c), be presented at the position (in the example of figure, display position rises) of regulation.In addition, in the case of ultrasonic transmission/reception face 120 from directly over abnormal position, left certain more than, icon A, as shown in Figure 34 (d), is presented at and Figure 34 (a), position that Figure 34 (b) is identical.
(variation 5)
Figure 35 (a)～(d) is example along with detector and the abnormal position of determining approach and the figure of the sample state of the amplitude variations of the swing of icon.
For example, shown in for example Figure 35 of amplitude (a), Figure 35 (b) of the swing of the icon A showing in the picture upper right of the ultrasonography shown in Figure 30, become near and change along with surveyed the distance of the abnormal position determined and detector by organism photometry, when close to abnormal position, the swing with peak swing as shown in Figure 35 (c) is shown.In addition, at ultrasonic transmission/reception face 120, from having left directly over abnormal position, the amplitude of the swing of icon A is as shown in Figure 35 (d), along with detector leaves and diminishes from abnormal position.
(variation 6)
Figure 36 (a)～(d) is example along with detector and the abnormal position of determining approach and the figure of the sample state of the change of shape of icon.
For example, shown in for example Figure 36 of shape (a), Figure 36 (b) of the icon A showing in the picture upper right of the ultrasonography shown in Figure 30, become near and change (in the example of figure, the number of protuberance increases) along with surveyed the distance of the abnormal position determined and detector by organism photometry, when close to abnormal position, as shown in Figure 36 (c), show with the maximum shape of protuberance.In addition, at ultrasonic transmission/reception face 120, from having left directly over abnormal position, the shape of icon A is as shown in Figure 36 (d), and the mode that protuberance tails off to leave from abnormal position along with detector changes.
Wherein, show the various display cases of the state that approaches for notifying abnormal position and detector.These explicit representations certainly can combination in any.For example, the explicit representation that also can carry out except the color change of the icon based on shown in this variation 1, can also combination of bright degree change, the size etc. that also can make light on and off cycle, display area, shape, swing with approach state and change accordingly simultaneously.Thus, can point out with the higher form of visuognosis the state that approaches of abnormal position and detector.
According to above-described structure, can be by the state that approaches of the detector on the abnormal position in subject and subject surface on the picture that shows ultrasonography, by lightness, color, light on and off cycle, display area, shape, the amplitude of swing or their combination of icon, carry out vision and point out.Thus, examiner do not make sight line back and forth also can visuognosis ultrasonography and detector operation support information.In addition, the detector operation information of supporting is prompted as the variation of the lightness of icon etc.Therefore, can not hinder the attention of examiner to ultrasonic diagnosis image, the detector operation that prompting can be grasped rapidly and is simply supported information.
Several embodiment of the present invention has been described, these embodiment indications are pointed out as an example, and are not intended to limit scope of invention.These new embodiments can be implemented with other various forms, can carry out various omissions, displacement, change in the scope of the main idea that does not depart from invention.These embodiments and distortion thereof are comprised in scope of invention and main idea, and are comprised in the invention that claims record and in the scope being equal to.

Claims (19)

1. a diagnostic ultrasound equipment, wherein, possesses:
Ultrasonic detector, sends ultrasound wave from ultrasonic transmission/reception towards subject, is received in via described ultrasonic transmission/reception face the ultrasound wave being reflected in described subject;
Photo-detector, there is illumination part and multiple optical detection part, this illumination part is around described ultrasonic transmission/reception face, be arranged on the central shaft of long side direction of described ultrasonic transmission/reception face, from at least one position to described subject internal radiation light, the plurality of optical detection part, around described ultrasonic transmission/reception face, take the central shaft of the long side direction of described ultrasonic transmission/reception face as axis of symmetry is configured in diverse location, detects the light intensity being reflected in described subject;
Image generation unit, uses the ultrasound wave being received by described ultrasonic detector, generates ultrasonography;
Computing unit, the light intensity detecting based on described each optical detection part, calculating illustrates abnormal portion bit position and the size of the absorption coefficient of light of regulation in described subject; And
Display unit, shows the described ultrasonography that described abnormal portion bit position and size are expressed.
2. diagnostic ultrasound equipment as claimed in claim 1, wherein,
Also possess:
Memory element, by abnormal portion bit position and size in described subject, according to each combination of the light intensity of the position of described multiple optical detection parts, stores in advance;
Described computing unit, by the combination of light intensity and the combination of the light intensity of storing in described memory element that relatively detect in described each optical detection part, calculates abnormal portion bit position and the size of the absorption coefficient of light that regulation is shown in described subject.
3. diagnostic ultrasound equipment as claimed in claim 1 or 2, wherein,
Described multiple optical detection part is provided with at least four pairs take the central shaft of the long side direction of described ultrasonic transmission/reception face as axis of symmetry.
4. diagnostic ultrasound equipment as claimed in claim 1 or 2, wherein,
Described illumination part is from more than two position light irradiations,
Described multiple optical detection part is provided with at least two pairs take the central shaft of the long side direction of described ultrasonic transmission/reception face as axis of symmetry.
5. diagnostic ultrasound equipment as claimed in claim 1 or 2, wherein,
Described illumination part irradiates the light that comprises at least two kinds of frequencies,
Described multiple optical detection part is provided with at least three pairs take the central shaft of the long side direction of described ultrasonic transmission/reception face as axis of symmetry.
6. the diagnostic ultrasound equipment as described in any one in claim 1 to 5, wherein,
Also possess:
Approach information generating unit, based on described abnormal portion bit position and the size calculating, generate for representing the approach information of described ultrasonic transmission/reception towards the situation that approaches at described abnormal position.
7. diagnostic ultrasound equipment as claimed in claim 6, wherein,
Described display unit shows the described information that approaches together with described ultrasonography.
8. diagnostic ultrasound equipment as claimed in claim 7, wherein,
The described information that approaches is, the lightness of the part by making picture corresponding to the distance between described ultrasonic transmission/reception face and described abnormal position changes, and represents the approach situation of described ultrasonic transmission/reception towards described abnormal position.
9. diagnostic ultrasound equipment as claimed in claim 7, wherein,
The described information that approaches is, by make the area change of a part for picture corresponding to the distance between described ultrasonic transmission/reception face and described abnormal position, to represent the approach situation of described ultrasonic transmission/reception towards described abnormal position.
10. diagnostic ultrasound equipment as claimed in claim 7, wherein,
The described information that approaches is, by make the light on and off frequency change of a part for picture corresponding to the distance between described ultrasonic transmission/reception face and described abnormal position, to represent the approach situation of described ultrasonic transmission/reception towards described abnormal position.
11. diagnostic ultrasound equipments as claimed in claim 7, wherein,
The described information that approaches is, by the amplitude variations that makes the part vibration of picture show corresponding to the distance between described ultrasonic transmission/reception face and described abnormal position, to represent the approach situation of described ultrasonic transmission/reception towards described abnormal position.
12. diagnostic ultrasound equipments as claimed in claim 7, wherein,
The described information that approaches is, by make the foxy of a part for picture corresponding to the distance between described ultrasonic transmission/reception face and described abnormal position, to represent the approach situation of described ultrasonic transmission/reception towards described abnormal position.
13. diagnostic ultrasound equipments as claimed in claim 7, wherein,
The described information that approaches is, by make the change in location of the icon on picture corresponding to the distance between described ultrasonic transmission/reception face and described abnormal position, to represent the approach situation of described ultrasonic transmission/reception towards described abnormal position.
14. diagnostic ultrasound equipments as claimed in claim 7, wherein,
The described information that approaches is, by make the change of shape of a part for picture corresponding to the distance between described ultrasonic transmission/reception face and described abnormal position, to represent the approach situation of described ultrasonic transmission/reception towards described abnormal position.
15. diagnostic ultrasound equipments as described in any one in claim 1 to 14, wherein,
The light intensity of described computing unit based on detecting in described each optical detection part, calculates the degree of being close on described each optical detection part and described subject surface,
This diagnostic ultrasound equipment also possesses:
Support information generating unit, based on the described degree of being close to calculating, generate the support information of the operation for supporting described ultrasonic detector; And
Support information output unit, export described support information.
16. diagnostic ultrasound equipments as claimed in claim 15, wherein,
Described support packets of information is containing the position of described ultrasonic detector, at least one in, posture, pressurization degree.
17. diagnostic ultrasound equipments as claimed in claim 15, wherein,
Described support packets of information is containing for so that the mode of the signal intensity sum maximum from described abnormal position that described multiple optical detection part detects configures the information of described photo-detector and described ultrasonic detector.
18. diagnostic ultrasound equipments as claimed in claim 1, wherein,
The variation of the light intensity of described computing unit based on described ultrasonography and described multiple optical detection part detections, calculates described abnormal portion bit position and size.
19. diagnostic ultrasound equipments as claimed in claim 1, wherein,
Described illumination part irradiation comprises the light as the first wave long component of the absorbing wavelength band at described abnormal position and the second wave length composition except the absorbing wavelength band at described abnormal position,
The detection light intensity that described computing unit comparison is caused by described first wave long component and the detection light intensity being caused by described second wave length composition, calculate described abnormal portion bit position and size.
CN201310532739.2A 2012-10-31 2013-10-31 Ultrasonic diagnosis device Pending CN103784165A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2012-240989 2012-10-31
JP2012240989 2012-10-31
JP2013-140968 2013-07-04
JP2013140968A JP6144131B2 (en) 2012-10-31 2013-07-04 Ultrasonic diagnostic equipment

Publications (1)

Publication Number Publication Date
CN103784165A true CN103784165A (en) 2014-05-14

Family

ID=50660526

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310532739.2A Pending CN103784165A (en) 2012-10-31 2013-10-31 Ultrasonic diagnosis device

Country Status (1)

Country Link
CN (1) CN103784165A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017164054A (en) * 2016-03-14 2017-09-21 株式会社東芝 Ultrasonic diagnosis apparatus and biological examination apparatus
CN108008696A (en) * 2016-10-27 2018-05-08 大隈株式会社 Diagnostic result display methods and diagnostic device in diagnostic device
CN110494087A (en) * 2017-03-30 2019-11-22 京瓷株式会社 Ultrasonic wave irradiation device
CN111194185A (en) * 2017-10-02 2020-05-22 百合医疗科技株式会社 Medical imaging device
CN112367923A (en) * 2018-07-13 2021-02-12 古野电气株式会社 Ultrasonic imaging device, ultrasonic imaging system, ultrasonic imaging method, and ultrasonic imaging program

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1575771A (en) * 2003-06-25 2005-02-09 阿洛卡株式会社 Ultrasound diagnosis apparatus
JP2007020735A (en) * 2005-07-13 2007-02-01 Toshiba Corp Biological light measuring device
US20090082668A1 (en) * 2007-09-21 2009-03-26 Kabushiki Kaisha Toshiba Ultrasonic imaging apparatus and method for generating ultrasonic image
JP2009077931A (en) * 2007-09-26 2009-04-16 Toshiba Corp Biological testing device and biological testing method
WO2009131027A1 (en) * 2008-04-25 2009-10-29 株式会社 日立メディコ Reference deformable body, ultrasonic diagnostic apparatus, and ultrasonic diagnostic method

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1575771A (en) * 2003-06-25 2005-02-09 阿洛卡株式会社 Ultrasound diagnosis apparatus
JP2007020735A (en) * 2005-07-13 2007-02-01 Toshiba Corp Biological light measuring device
US20090082668A1 (en) * 2007-09-21 2009-03-26 Kabushiki Kaisha Toshiba Ultrasonic imaging apparatus and method for generating ultrasonic image
JP2009077931A (en) * 2007-09-26 2009-04-16 Toshiba Corp Biological testing device and biological testing method
WO2009131027A1 (en) * 2008-04-25 2009-10-29 株式会社 日立メディコ Reference deformable body, ultrasonic diagnostic apparatus, and ultrasonic diagnostic method

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017164054A (en) * 2016-03-14 2017-09-21 株式会社東芝 Ultrasonic diagnosis apparatus and biological examination apparatus
CN108008696A (en) * 2016-10-27 2018-05-08 大隈株式会社 Diagnostic result display methods and diagnostic device in diagnostic device
CN110494087A (en) * 2017-03-30 2019-11-22 京瓷株式会社 Ultrasonic wave irradiation device
CN111194185A (en) * 2017-10-02 2020-05-22 百合医疗科技株式会社 Medical imaging device
CN112367923A (en) * 2018-07-13 2021-02-12 古野电气株式会社 Ultrasonic imaging device, ultrasonic imaging system, ultrasonic imaging method, and ultrasonic imaging program
US11948324B2 (en) 2018-07-13 2024-04-02 Furuno Electric Company Limited Ultrasound imaging device, ultrasound imaging system, ultrasound imaging method, and ultrasound imaging program

Similar Documents

Publication Publication Date Title
JP6659766B2 (en) Optical measuring device and ultrasonic diagnostic device
CN109044282B (en) Detection device and detection method integrating touch sensing and optical tomography imaging
JP5836760B2 (en) Acoustic wave acquisition apparatus and acoustic wave acquisition method
CN103784165A (en) Ultrasonic diagnosis device
CN106560160A (en) Object Information Acquiring Apparatus And Control Method Thereof
WO2015107794A1 (en) Photoacoustic measurement apparatus and signal-processing device and signal-processing method used in same
WO2016051734A1 (en) Object-information acquisition apparatus
WO2013103935A1 (en) Near-infrared (nir) optical scanner
JP2016064113A (en) Ultrasonic diagnostic apparatus and biological light measurement device
EP2837333A2 (en) Biological optical measurement apparatus and ultrasound diagnostic apparatus
JP2009077931A (en) Biological testing device and biological testing method
KR102578072B1 (en) Ultrasound diagnositic apparatus and controlling mehtod of the same
JP6358573B2 (en) Operation method of breast measurement apparatus and breast measurement apparatus
CN108601536A (en) Information acquisition device and control method
JP2015123252A (en) Light measurement device for living body, ultrasonic diagnostic device and light measurement method for living body
JP2019165836A (en) Subject information acquisition device, and control method therefor
JPWO2018146929A1 (en) Photoacoustic image generator
US20160270765A1 (en) Ultrasonic diagnostic apparatus and biometric examination apparatus
US10603017B2 (en) Ultrasound diagnostic apparatus and biomedical examination apparatus
JP2014239815A (en) Biological examination apparatus and ultrasound diagnostic apparatus
JP6486733B2 (en) Ultrasonic diagnostic apparatus and biopsy apparatus
US20200100765A1 (en) Acoustic wave diagnostic apparatus and operation method of acoustic wave diagnostic apparatus
JP2015173922A (en) Ultrasonic diagnostic device and ultrasonic diagnostic device controlling method
JP2018102359A (en) Processing device and processing method
JP2017164222A (en) Processing device and processing method

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20140514