CN103768997A - Atorvastatin calcium and midbody production process system - Google Patents
Atorvastatin calcium and midbody production process system Download PDFInfo
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- CN103768997A CN103768997A CN201410048559.1A CN201410048559A CN103768997A CN 103768997 A CN103768997 A CN 103768997A CN 201410048559 A CN201410048559 A CN 201410048559A CN 103768997 A CN103768997 A CN 103768997A
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- atorvastatin calcium
- control device
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Abstract
The invention relates to an atorvastatin calcium and midbody production process system. The atorvastatin calcium and midbody production process system comprises a reaction kettle, a discharge valve, a vacuum tank, a buffer tank, a vacuum pump and a centrifugal machine which are sequentially connected to one another through pipelines. The atorvastatin calcium and midbody production process system also comprises a refrigeration circulating water pipe, a pressure control device and a temperature control device which are respectively connected to a reaction kettle, wherein a pressure relief control valve is arranged at the lower part of the pressure control device and is connected to a pressure relief pipe; and the lower part of the temperature control device is connected to the refrigeration circulating water pipe through a refrigeration circulating water control valve. The atorvastatin calcium and midbody production process system is suitable for crystallization process in chemical engineering industries and pharmaceutical industries.
Description
Technical field
The present invention relates to chemical industry equipment field.
Background technology
Preparing in Atorvastatin calcium and intermediate process, in crystallization process, due to persistently overheating, temperature in the kettle, pressure are higher, if pressure, temperature exceed higher limit, operating personnel operate not in time, and in still, material may decompose, the too high material accident of rushing that causes of still internal pressure, causes damage to personnel and equipment.
Summary of the invention
Goal of the invention: in order to overcome above-mentioned defect, the invention provides a kind of safe process unit.
The technical solution used in the present invention: a kind of Atorvastatin calcium and intermediate production technology system, comprise pipeline connects successively reactor, baiting valve, vacuum pond, surge tank, vavuum pump, centrifuge, also comprise that freeze cycle water pipe, pressure control device, temperature control equipment are connected with described reactor respectively, pressure release control valve is installed in the downstream of described pressure control device, and this pressure release control valve is connected with relief tube; The downstream of described temperature control equipment is connected with described freeze cycle water pipe by freeze cycle water control valve.
As preferably, described pressure control device comprises pressure sensor, pressure display unit, pressure alarm, pressure release linkage.
As preferably, described temperature control equipment comprises temperature sensor, temperature indicator, temperature alarm, freeze cycle linkage.
Useful effect: adopt pressure control device, when the pressure value of overstepping the extreme limit, pressure alarm is reported to the police, and pressure release linkage is opened pressure release control valve, and pressure can discharge by relief tube in time, avoids hypertonia, rushes material accident; Adopt temperature control equipment, when temperature in the kettle is higher than higher limit, temperature alarm is reported to the police, and freeze cycle linkage is opened freezing recirculated water control valve, and freeze cycle water reduces temperature in the kettle, avoids occurring material and decomposes and fire incident.
Accompanying drawing explanation
Fig. 1 is schematic diagram of the present invention.
The specific embodiment
Below in conjunction with accompanying drawing explanation and the specific embodiment, the invention will be further described, but protection scope of the present invention is not limited to the following examples.
As shown in Figure 1, a kind of Atorvastatin calcium and intermediate production technology system, comprise pipeline connects successively reactor 1, baiting valve 6, vacuum pond 2, surge tank 3, vavuum pump 4, centrifuge 5, also comprise that freeze cycle water pipe 11, pressure control device 7, temperature control equipment 8 are connected with described reactor 1 respectively, pressure release control valve 10 is installed in the downstream of described pressure control device 7, and this pressure release control valve 10 is connected with relief tube 12; The downstream of described temperature control equipment 7 is connected with described freeze cycle water pipe 11 by freeze cycle water control valve 9.
Described pressure control device 7 comprises pressure sensor, pressure display unit, pressure alarm, pressure release linkage.Described temperature control equipment 8 comprises temperature sensor, temperature indicator, temperature alarm, freeze cycle linkage.
Adopt pressure control device 7, when the pressure value of overstepping the extreme limit, pressure alarm is reported to the police, and pressure release linkage is opened pressure release control valve, and pressure can discharge by relief tube in time, avoids hypertonia, rushes material accident; Adopt temperature control equipment 8, when temperature in the kettle is higher than higher limit, temperature alarm is reported to the police, and freeze cycle linkage is opened freezing recirculated water control valve, and freeze cycle water reduces temperature in the kettle, avoids occurring material and decomposes and fire incident.
Claims (3)
1. an Atorvastatin calcium and intermediate production technology system, comprise the reactor (1) that pipeline connects successively, baiting valve (6), vacuum pond (2), surge tank (3), vavuum pump (4), centrifuge (5), it is characterized in that: also comprise freeze cycle water pipe (11), pressure control device (7), temperature control equipment (8) is connected with described reactor (1) respectively, pressure release control valve (10) is installed in the downstream of described pressure control device (7), this pressure release control valve (10) is connected with relief tube (12), the downstream of described temperature control equipment (7) is connected with described freeze cycle water pipe (11) by freeze cycle water control valve (9).
2. Atorvastatin calcium according to claim 1 and intermediate production technology system, is characterized in that: described pressure control device (7) comprises pressure sensor, pressure display unit, pressure alarm, pressure release linkage.
3. Atorvastatin calcium according to claim 1 and intermediate production technology system, is characterized in that: described temperature control equipment (8) comprises temperature sensor, temperature indicator, temperature alarm, freeze cycle linkage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410048559.1A CN103768997A (en) | 2014-02-11 | 2014-02-11 | Atorvastatin calcium and midbody production process system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410048559.1A CN103768997A (en) | 2014-02-11 | 2014-02-11 | Atorvastatin calcium and midbody production process system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103768997A true CN103768997A (en) | 2014-05-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410048559.1A Pending CN103768997A (en) | 2014-02-11 | 2014-02-11 | Atorvastatin calcium and midbody production process system |
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| Country | Link |
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| CN (1) | CN103768997A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN202482243U (en) * | 2012-03-06 | 2012-10-10 | 广西桂平市巴帝食品有限责任公司 | Reaction system for producing caramel pigment |
| CN202778472U (en) * | 2012-07-16 | 2013-03-13 | 东北石油大学 | Chemical synthesis device |
| CN103007852A (en) * | 2011-09-20 | 2013-04-03 | 刘顺兆 | Reaction kettle pressure regulation apparatus |
| CN203209025U (en) * | 2013-03-20 | 2013-09-25 | 岳阳市中顺化工有限责任公司 | Vacuum system for producing trioctyl phosphate |
-
2014
- 2014-02-11 CN CN201410048559.1A patent/CN103768997A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103007852A (en) * | 2011-09-20 | 2013-04-03 | 刘顺兆 | Reaction kettle pressure regulation apparatus |
| CN202482243U (en) * | 2012-03-06 | 2012-10-10 | 广西桂平市巴帝食品有限责任公司 | Reaction system for producing caramel pigment |
| CN202778472U (en) * | 2012-07-16 | 2013-03-13 | 东北石油大学 | Chemical synthesis device |
| CN203209025U (en) * | 2013-03-20 | 2013-09-25 | 岳阳市中顺化工有限责任公司 | Vacuum system for producing trioctyl phosphate |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent of invention or patent application | ||
| CB02 | Change of applicant information |
Address after: 226200 No. 338, Shanghai Road, Binjiang fine chemical industry zone, Qidong, Jiangsu Applicant after: The sincere pharmaceutcal corporation, Ltd in Jiangsu Address before: 226200 No. 338, Shanghai Road, Binjiang fine chemical industry zone, Qidong, Jiangsu Applicant before: Jiangsu Chengxin Pharmaceutical Co., Ltd. |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20140507 |