CN103721305A - Blood leukocyte filtering monitoring system and method - Google Patents

Blood leukocyte filtering monitoring system and method Download PDF

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Publication number
CN103721305A
CN103721305A CN201410002137.0A CN201410002137A CN103721305A CN 103721305 A CN103721305 A CN 103721305A CN 201410002137 A CN201410002137 A CN 201410002137A CN 103721305 A CN103721305 A CN 103721305A
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blood
time
measuring device
column
monitoring system
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CN201410002137.0A
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CN103721305B (en
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赵利明
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Shenzhen Meister Biomedical Engineering Co.,Ltd.
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SHENZHEN PONTED BIO-MED Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Veterinary Medicine (AREA)
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Abstract

The invention discloses a blood leukocyte filtering monitoring system which comprises a filtering device, a weight measuring device, a time measuring device and a storing device. The weight measuring device is used for collecting blood weight parameters before filtering during a filtering process in real time. The time measuring device is used for measuring time during the filtering process. The weight measuring device and the time measuring device are electrically connected. The time measuring device and the storing device are electrically connected. The weight measuring device and the time measuring device collect data of the filtering process in real time. The collected data are sent to the storing device which stores the parameters. Corresponding data are measured through a weight sensor and the time measuring device, the measured data are stored in a magnetic disk, accordingly, the objective real-time data about the influence on blood quality of the filtering process are obtained, the most primitive data are provided for blood quality researching after filtering, and the research on blood quality after filtering is promoted.

Description

Blood leucocyte filters monitoring system and method
Technical field
The present invention relates to blood leucocyte and filter monitoring field, relate in particular to blood leucocyte and filter monitoring system and method.
Background technology
Blood leucocyte is the main factor that clinical blood transfusion causes transfusion reaction, therefore, the leukocyte of removing in blood constituent before blood transfusion has become the routine operation in blood collecting and supplying activity, main method is to utilize the leucocyte filter being connected between blood collection bags and collecting bag, whole blood or blood constituent pass through filter under self gravitation effect, erythrocyte passes through smoothly because of small volume, and leukocyte, because volume is compared with being retained in filter greatly, reaches and filters leukocytic object.But the white device of current filter cannot carry out Real-Time Monitoring to filter process, can not provide the objective real time data of filter process on blood quality impact.
Foregoing only, for auxiliary understanding technical scheme of the present invention, does not represent and admits that foregoing is prior art.
Summary of the invention
Main purpose of the present invention is to provide a kind of blood leucocyte filter process monitoring system and method with identical inventive concept, is intended to leukoreduction filter process carry out Real-Time Monitoring and record monitoring result record, and the foundation of assessment blood filter white matter amount is provided.
For achieving the above object, a kind of blood leucocyte filter process monitoring system provided by the invention, comprise for the leukocytic defecator of filtering blood, described blood leucocyte filter process monitoring system also comprises: for the Weight-measuring device of blood weight parameter before the filtration of Real-time Collection filter process, for filter process being carried out to the time measurement device of measure of time, and for storing the storage device of described Weight-measuring device and data that described time measurement device is surveyed; Described Weight-measuring device is electrically connected with described storage device, and described time measurement device is electrically connected with described storage device;
Described Weight-measuring device and described time measurement device are real-time must carry out data acquisition to filter process, and the data that collect are sent to described storage device, and described storage device is stored this parameter.
Preferably, described blood leucocyte filter process monitoring system also comprise for place be equipped with filter before blood the first container the first fixture, for placing the second fixture and the frame in order to the second container of blood after accommodating filtration, wherein, described frame comprises top board, base plate, side plate and column, the upper end of described side plate is fixedly connected with described top board, and lower end is fixedly connected with described base plate; The upper end of described column is arranged on described top board, and lower end is arranged on described base plate, and described column can be to cross its type heart and to rotate as axle perpendicular to the straight line of described top board; Described measuring device is connected with described the first fixture, and described the first fixture is arranged at described column upper end, and described the second fixture is arranged at described column lower end.
Preferably, some described the first fixtures evenly arrange around described column, and some described the second fixtures evenly arrange around described column.
Preferably, described blood leucocyte filter process monitoring system also comprises the heat sealing head for described second container being carried out to sterile sealing, and wherein, described heat sealing head is arranged on described column.
Preferably, on described column, be also arranged with the rotation disc for rotating column.
Preferably, described blood leucocyte filter process monitoring system also comprises the evaluator for identifying described the first container and second container, and described evaluator is arranged on described column, and described evaluator is electrically connected with described control device.
Preferably, described blood leucocyte filter process monitoring system also comprises the information processor that described Weight-measuring device and data that described time measurement device is surveyed are carried out to computing, and described measurement data can obtain the flow velocity of blood in filter process through described information processor processing.
Preferably, described blood leucocyte filter process monitoring system also comprises showing the display screen of the rear information of described information processor processing, and described display screen is electrically connected with described information processor.
By gravity sensor and time measurement device, measure corresponding data, and measured data are stored in disk, thereby obtain the objective real time data of filter process on blood quality impact, for the blood quality after research filtration provides the most original data, be conducive to the research to filtering rear blood quality.
Accompanying drawing explanation
Fig. 1 is the structural representation that blood leucocyte of the present invention filters monitoring system;
Fig. 2 is the structure for amplifying schematic diagram at A place in Fig. 1;
Fig. 3 is the structural representation at B place in Fig. 1;
Fig. 4 is the plan structure schematic diagram of Fig. 3;
Fig. 5 is the axle geodesic structure schematic diagram of Fig. 3;
Fig. 6 is the structure for amplifying schematic diagram at C place in Fig. 5;
Fig. 7 is the structure for amplifying schematic diagram at D place in Fig. 5;
Fig. 8 is the structural representation that blood leucocyte of the present invention filters monitoring system the second fixture;
Fig. 9 is the schematic flow sheet that blood leucocyte of the present invention filters monitoring method the first embodiment;
Figure 10 is the schematic flow sheet that blood leucocyte of the present invention filters monitoring method the second embodiment.
Realization, functional characteristics and the advantage of the object of the invention, in connection with embodiment, are described further with reference to accompanying drawing.
The specific embodiment
Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
The invention provides the monitoring system that a kind of blood leucocyte filters, referring to figs. 1 through Fig. 5, Fig. 1 is the structural representation that blood leucocyte of the present invention filters monitoring system; Fig. 2 is the structure for amplifying schematic diagram at A place in Fig. 1; Fig. 3 is the structural representation at B place in Fig. 1; Fig. 4 is the plan structure schematic diagram of Fig. 3; Fig. 5 is the axle geodesic structure schematic diagram of Fig. 3.
In an embodiment of the present invention, comprise for the leukocytic defecator of filtering blood, also comprise: for the Weight-measuring device 110 of blood weight parameter before the filtration of Real-time Collection filter process, for filter process being carried out to the time measurement device of measure of time, and for storing the storage device of Weight-measuring device 110 and data that time measurement device is surveyed; Weight-measuring device 110 is electrically connected with storage device, and time measurement device is electrically connected with storage device;
Weight-measuring device 110 and time measurement device are real-time must carry out data acquisition to filter process, and the data that collect are sent to storage device, and storage device is stored this parameter.
Particularly, as shown in Figures 1 to 5, in the present embodiment, the first container is female blood bag or female blood bottle, the first fixture is hook 203, and second container is sub-blood bag or sub-blood bottle, and the second fixture 30 is containing cavity 301, female blood bag hangs on hook 203, by the road for transmitting blood, manages and for the leukocytic filter of filtering blood, blood is transported to from top to bottom the sub-blood bag that is placed on containing cavity 301.Weight-measuring device 110 is gravity sensor 110 or other device that can measure gravity, and time measurement device is the timer associated with Weight-measuring device 110.Storage device is disk or hard disk.Before filtration that gravity sensor 110 records in real time, the weight parameter of blood is real-time is stored into disk.The time measurement device corresponding with gravity sensor 110 is by the disk that the is stored into real-time time parameter recording.
In the present embodiment, by gravity sensor 110 and time measurement device, measure corresponding data, and measured data are stored in disk, thereby obtain the objective real time data of filter process on blood quality impact, for the blood quality after research filtration provides the most original data, be conducive to the research to filtering rear blood quality.
Further, blood leucocyte filter monitoring system also comprise for place be equipped with filter before blood the first container the first fixture, for placing the second fixture 30 and the frame 10 in order to the second container of blood after accommodating filtration, wherein, frame 10 comprises top board 101, base plate 102, side plate 103 and column 104, the upper end of side plate 103 is fixedly connected with top board 101, and lower end is fixedly connected with base plate 102; The upper end of column 104 is arranged on top board 101, and lower end is arranged on base plate 102, and column 104 can be to cross its type heart and to rotate as axle perpendicular to the straight line of top board 101; Measuring device is connected with the first fixture, and the first fixture is arranged at column 104 upper ends, and the second fixture 30 is arranged at column 104 lower ends.
Particularly, with reference to Fig. 1,204 upper ends, two side are all fixedly connected with top board 101, and lower end is all fixedly connected with base plate 102, form a rectangular frame.The upper end of column 104 is connected with top board 101, and lower end is connected with base plate 102, for hanging the hook 203 of female blood bag, is arranged on column 104 upper ends, is arranged on the lower end of column 104 for placing the containing cavity 301 of sub-blood bag, and hook 203 and containing cavity are corresponding Shang Xia 301.As shown in Figure 7, on gravity sensor 110, be fixedly installed a spring leaf 120, on spring leaf 120, be provided with screwed hole, the end of hook 203 is used screw 130 to be threaded by screwed hole with spring leaf 120, and hook 203 gravity that bear can be delivered on gravity sensor 110 by spring leaf 120.Certainly, this is a kind of connected mode of gravity sensor 110 and hook 203, and in other embodiment, the two also can be by connecting as connected modes such as engaging, fastenings.
In the present embodiment, by column 104, female blood bag is arranged to the top of sub-blood bag, makes the blood in female blood bag under the effect of deadweight, flow into sub-blood bag, the pollution of having avoided other optional equipments such as working pressure pump to bring.In addition, between hook 203 and gravity sensor 110, be threaded connection, reliable and stable, convenient disassembly, is conducive to the maintenance to fixture.
Further, some the first fixtures evenly arrange around column 104, and some the second fixtures 30 evenly arrange around column 104.
Particularly, as shown in Fig. 3, Fig. 4, Fig. 5 and Fig. 8, in the present embodiment, the monitoring system that blood leucocyte filters includes extension dish 20, and extension dish 20 comprises fixed base plate 201, sidewall 204 and hook 203, wherein, fixed base plate 201 is cylinder, column 104 is parallel and run through the central axis of fixed base plate 201, on fixed base plate 201, take its center of circle, bottom surface, evenly offers multiple installing holes 202 on the circumference in the center of circle, and hook 203 is arranged on fixed base plate 201 through installing hole 202.Sidewall 204 is fixedly mounted on the circumference of fixed base plate 201.Multiple containing cavities 301 are evenly arranged at around column 104 around column 104, and are fixed on column 104.Certainly, in other embodiments, hook 203 and containing cavity 301 can be with other shapes beyond circle, as regular polygon is centered around around column 104.
In the present embodiment, by arranging, multiplely for hanging the hook 203 of blood bag and the containing cavity 301 for accommodating blood bag, can to the filter process of multiple blood bags, monitor simultaneously, be conducive to improve the work efficiency of monitoring system.
Further, the monitoring system that blood leucocyte filters also comprises the heat sealing head 80 for second container being carried out to sterile sealing, and wherein, heat sealing head 80 is arranged on column 104.
Particularly, in the present embodiment, the monitoring system that blood leucocyte filters comprises a function panel 60, and function panel 60 is set on column 104, and heat sealing head 80 is fixedly mounted on function panel 60.After the blood filtration in blood bag, the road pipe of transportation blood is put into heat sealing head 80, make the road seal of tube, reach the object of the sub-blood bag of sealing.
In the present embodiment, by heat sealing head 80 is arranged on control panel, after filter process completes, the pipe that just can directly satisfy the need carries out sterile sealing, without transferring to other position, seal, be conducive to completing of seal process, make the sealing of sub-blood bag become aspect quick.
Further, column 104 can rotate with respect to base plate 102 and top board 101, is also arranged with the rotation disc 90 for rotating column 104 on column 104.
Particularly, as shown in Fig. 3, Fig. 6 and Fig. 8, in the present embodiment, column 104 is that two ends diameter is little, the multidiameter that mid diameter is large, on the correspondence position of top board 101 and base plate 102, be all provided with installing hole, bearing 140 is installed in installing hole, and the part that column 104 diameters are little is arranged in bearing 140, and column 104 is vertically arranged, bearing 140 and installing hole interference fit, column 104 and bearing 140 interference fit.The mounting base 102 of extension dish 20 is fixedly mounted on column 104, and accommodating appearance is fixedly mounted on column 104.Rotation disc 90 fixed covers are located on column 104, and when rotating rotation disc 90, column 104 can rotate with rotation disc 90, thereby band moving hanging disk 20 and containing cavity 301 rotate.
In the present embodiment, can rotate relative to top board 101 and base plate 102 by column 104 is set to, make to connect female blood bag and Zi Xuedai road pipe can be adjusted at any time, avoid road pipe to be wound around or knotting, be conducive to the normal filtration of blood middle leukocytes.In addition, when the blood bag filtration at heat sealing head 80 sides and the back side completes, can pass through Rotary cloumn 104, make the blood bag having filtered towards heat sealing head 80, be conducive to the heat seal sealing of road pipe.The setting of rotation disc 90, makes the rotation of column 104 become convenient and swift.
Further, with reference to Fig. 2, the monitoring system that blood leucocyte filters also comprises the evaluator 70 for identifying the first container and second container, and evaluator 70 is arranged on column 104, and evaluator 70 is electrically connected with control device 100.
Particularly, as shown in Figure 2, in the present embodiment, evaluator 70 is scanner 70, and scanner 70 is fixedly mounted on function panel 60.On female blood bag and sub-blood bag, post corresponding bar code.Before filtration, need by scanner 70, the bar code on blood bag to be scanned, with the information to blood, confirm, guarantee the corresponding one by one of female blood bag and sub-blood bag simultaneously.On the sidewall 204 of extension dish 20, be provided with display lamp 150, display lamp 150 is electrically connected with single-chip microcomputer 100.Display lamp 150 is for display scanner 70 scanning results and filter process state, when scanning result meets, filters while requiring, and display lamp 150 be green, when not meeting, filters while requiring scanning result, display lamp 150 is red, and when filter process completes, display lamp 150 glimmers.
In the present embodiment, by scanner 70 is set, can conveniently confirm the parameter such as blood group, blood volume of blood in blood bag, can also guarantee female blood bag simultaneously and sub-blood bag is corresponding places, avoid obscuring the generation of blood bag.The setting of display lamp 150, effectively prevents the blood filtration under error condition, has reduced owing to filtering the improper blood waste causing.
Further, the monitoring system that blood leucocyte filters, also comprise the information processor that Weight-measuring device 110 and data that time measurement device is surveyed are carried out to computing, through information processor, processing can obtain the flow velocity of blood in filter process to measurement data.
Particularly, in the present embodiment, information processing apparatus is set to main frame 50, computer carries out correlation computations by gravity sensor 110 by the weight parameter of blood before the filtration recording and time parameter that time measurement device records, obtain the parameters such as the flow velocity of blood flow in blood filtration process, thereby obtain intuitively assessing the parameter of filter process.
Further, the monitoring system that blood leucocyte filters, also comprises the display screen of processing rear information in order to display information processor, and display screen is electrically connected with information processor.
Particularly, in the present embodiment, display screen is computer screen.Display screen is electrically connected with main frame 50, and main frame 50 is the data that receive in real time single-chip microcomputer 100 and import into, and processes data into the pattern that we need, as the flowing velocity curve of blood in filter process etc.The pattern curve negotiating display screen obtaining shows operator, and operator can clearly see in filter process in female blood bag the quality of blood over time and the process changing.
In the present embodiment, by display screen, by the mass change of blood in leukoreduction filter process and real-time being illustrated on display screen of correlated characteristic, operator can be known intuitively whole filter process is monitored in real time.Take some ultimate principles of blood filtration and experience as foundation, the curve of contrast real-time exhibition, can find to go wrong in filter process timely, and makes associative operation and solve, thereby is conducive to the control of operator to filter process.
The monitoring method that the invention provides a kind of blood leucocyte filtration of monitoring system of filtering based on blood leucocyte, with reference to Fig. 9, Fig. 9 is the schematic flow sheet that blood leucocyte of the present invention filters the first embodiment of monitoring method, comprises the following steps:
S10: Weight-measuring device measures mass parameter in real time to filtering front blood, time measurement device carries out measure of time to filter process and obtains time parameter;
The quality that front blood is filtered in the real-time measurement of gravity sensor, time measurement device carries out record to the sampled measurements time of gravity sensor.
S20: information processor calculates the flow velocity of blood in filter process according to mass parameter and corresponding time parameter;
According to the quality measuring and time parameter, carry out correlation computations, can obtain the flow velocity of blood in filter process, velocity of blood flow more can react the impact of filter process on blood intuitively.
S30: the velocity of blood flow calculating is stored to storage device;
Velocity of blood flow is stored to disk, during convenient use later, call.
This enforcement provides a kind of blood leucocyte to filter monitoring method, by the enforcement of above-mentioned steps, can obtain react the relevant parameter such as velocity of blood flow that filters blood quality afterwards, thereby obtain the objective real time data that filter process affects blood quality.
With reference to Figure 10, Figure 10 is the schematic flow sheet that blood leucocyte of the present invention filters the second embodiment of monitoring method, on the basis of above-described embodiment, after S30 step, also comprises:
S40: show the velocity of blood flow calculating by display screen.
By the isoparametric real-time change of velocity of blood flow in the real-time demonstration blood filtration process of display device.Be conducive to real-time filter process is monitored of staff, be conducive to adjust timely filter plant to reduce because filtering the improper blood waste causing.
These are only the preferred embodiments of the present invention; not thereby limit the scope of the claims of the present invention; every equivalent structure or conversion of equivalent flow process that utilizes description of the present invention and accompanying drawing content to do; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present invention.

Claims (10)

1. the monitoring system that blood leucocyte filters, comprise for the leukocytic defecator of filtering blood, it is characterized in that, also comprise: for the Weight-measuring device of blood weight parameter before the filtration of Real-time Collection filter process, for filter process being carried out to the time measurement device of measure of time, and for storing the storage device of described Weight-measuring device and data that described time measurement device is surveyed; Described Weight-measuring device is electrically connected with described storage device, and described time measurement device is electrically connected with described storage device;
Described Weight-measuring device and described time measurement device are real-time must carry out data acquisition to filter process, and the data that collect are sent to described storage device, and described storage device is stored this parameter.
2. the monitoring system that blood leucocyte as claimed in claim 1 filters, it is characterized in that, also comprise for place be equipped with filter before blood the first container the first fixture, for placing the second fixture and the frame in order to the second container of blood after accommodating filtration, wherein
Described frame comprises top board, base plate, side plate and column, and the upper end of described side plate is fixedly connected with described top board, and lower end is fixedly connected with described base plate;
The upper end of described column is arranged on described top board, and lower end is arranged on described base plate, and described column can be to cross its type heart and to rotate as axle perpendicular to the straight line of described top board;
Described measuring device is connected with described the first fixture, and described the first fixture is arranged at described column upper end, and described the second fixture is arranged at described column lower end.
3. the monitoring system that blood leucocyte as claimed in claim 2 filters, is characterized in that, some described the first fixtures evenly arrange around described column, and some described the second fixtures evenly arrange around described column.
4. the monitoring system that blood leucocyte as claimed in claim 3 filters, is characterized in that, also comprise the heat sealing head for described second container being carried out to sterile sealing, wherein, described heat sealing head is arranged on described column.
5. the monitoring system that blood leucocyte as claimed in claim 4 filters, is characterized in that, is also arranged with the rotation disc for rotating column on described column.
6. the monitoring system that blood leucocyte as claimed in claim 5 filters, is characterized in that, also comprise the evaluator for identifying described the first container and second container, described evaluator is arranged on described column, and described evaluator is electrically connected with described control device.
7. the monitoring system that blood leucocyte as claimed in claim 6 filters, it is characterized in that, also comprise the information processor that described Weight-measuring device and data that described time measurement device is surveyed are carried out to computing, described measurement data can obtain the flow velocity of blood in filter process through described information processor processing.
8. the monitoring system that blood leucocyte filters as claimed in any of claims 1 to 7 in one of claims, is characterized in that, also comprises showing the display screen of the rear information of described information processor processing, and described display screen is electrically connected with described information processor.
9. the monitoring method that the blood leucocyte of the monitoring system of filtering based on blood leucocyte claimed in claim 1 filters, is characterized in that, comprises the following steps:
Weight-measuring device measures mass parameter in real time to filtering front blood, and time measurement device carries out measure of time to filter process and obtains time parameter;
Information processor calculates the flow velocity of blood in filter process according to described mass parameter and corresponding time parameter;
The described velocity of blood flow calculating is stored to storage device.
10. blood leucocyte as claimed in claim 9 filters monitoring method, described, also comprises after the described velocity of blood flow calculating is stored to storage device step:
By display screen, show the described velocity of blood flow calculating.
CN201410002137.0A 2014-01-02 2014-01-02 Blood leucocyte filters monitoring system and method Active CN103721305B (en)

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Cited By (6)

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Publication number Priority date Publication date Assignee Title
CN106620911A (en) * 2017-01-22 2017-05-10 武汉佰美斯医疗科技有限公司 Leukocyte-filtering working table
CN106730076A (en) * 2017-01-22 2017-05-31 武汉佰美斯医疗科技有限公司 A kind of leukoreduction filter monitoring device
CN106890373A (en) * 2017-02-10 2017-06-27 广州上诺生物技术有限公司 A kind of method and system for digital management plasmapheresis leucocyte
CN108042860A (en) * 2017-12-29 2018-05-18 武汉佰美斯医疗科技有限公司 A kind of suspension arrangement with reciprocally swinging pallet
CN108325021A (en) * 2018-03-15 2018-07-27 广州上诺生物技术有限公司 System for filtering away white blood-cell from blood
CN114366840A (en) * 2022-01-12 2022-04-19 山东中保康医疗器具有限公司 Virus inactivation device based on blood bag management

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CN106620911A (en) * 2017-01-22 2017-05-10 武汉佰美斯医疗科技有限公司 Leukocyte-filtering working table
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CN108325021A (en) * 2018-03-15 2018-07-27 广州上诺生物技术有限公司 System for filtering away white blood-cell from blood
CN114366840A (en) * 2022-01-12 2022-04-19 山东中保康医疗器具有限公司 Virus inactivation device based on blood bag management

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