CN103709008A - Method for separating and purifying erythritol by membrane crystallization - Google Patents
Method for separating and purifying erythritol by membrane crystallization Download PDFInfo
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- CN103709008A CN103709008A CN201310694042.5A CN201310694042A CN103709008A CN 103709008 A CN103709008 A CN 103709008A CN 201310694042 A CN201310694042 A CN 201310694042A CN 103709008 A CN103709008 A CN 103709008A
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- erythritol
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
- C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
- C07C29/78—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by condensation or crystallisation
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention relates to a method for separating and purifying erythritol by membrane crystallization. The technical scheme is as follows: the method comprises the following steps: an erythritol crystallization mother solution is sent into a membrane component; water in the mother solution is subjected to membrane distillation, penetrates through the membrane in the form of steam and is condensed into liquid water on the other side of the membrane; the crystallization mother solution away from the membrane component is concentrated to an oversaturated state and sent into a crystallizer; erythritol crystals grow in the circulating crystallization mother solution in a fluidized suspension mode; the crystallization mother solution on the upper layer of the crystallizer is pumped into the membrane component to be subjected to internal circulation; and the erythritol crystallization product is led out via the lower part of the crystallizer, subjected to solid-liquid separation, and dried to obtain the erythritol crystals. The erythritol crystallization mother solution is evaporated and concentrated by membrane distillation to achieve the oversaturated state, and the crystals grow in the fluidized bed crystallizer, thereby providing favorable conditions for crystal growth; and the fluidized bed crystallizer has a size grading action, so that the particle size of the erythritol crystal product is large and uniform. The method can effectively lower the production cost for refining the erythritol crystals.
Description
Technical field
The invention belongs to multi-sugar alcohol production technical field, be specifically related to a kind of method of membrane crystallization separation and purification erythritol.
Background technology
Erythritol is a kind of natural saccharic and function sweeting agent, is widely used in developing the crowds' such as the uncomfortable disease of protective foods low in calories, diabetes and glucose functional food or beverage, the children special-purpose articles for use etc. that clean the teeth, and market outlook are very good.
Erythritol industrial production mainly adopts fermentation method, and fermented liquid is first evaporation concentration after purifying treatment, then crystallisation by cooling makes erythritol crystal.Because fermented liquid mesoerythrit concentration is lower, when atmospheric evaporation is concentrated, service temperature is higher, and water evaporation quantity is larger, and energy consumption is higher; Though and adopt decompression or multiple-effect evaporation to save energy and reduce the cost, but can increase the complicacy of equipment and process.
Membrane crystallization is the distillation of a kind of coupled film and the novel separating and purifying technology of crystallization, and its principle of operation is that application film distillation technology is removed the solvent in crystalline mother solution, makes it to reach hypersaturated state and makes solute crystallization.Compared to crystallisation by cooling process after conventional fermented erythritol liquor evaporative crystallization or first evaporation concentration, membrane crystallization is without fermented liquid is heated to boiling, only need maintain the suitable temperature head in film both sides, just can make water in fermented liquid see through fenestra with the form of water vapour, thereby realize the concentrated and oversaturated object of fermented liquid.There is the temperature difference in the crystalline mother solution surface of evaporation and crystal process and mother liquor body region (or in crystallisation by cooling process heat-transfer surface and mother liquor body region), this makes to have thermograde in evaporative crystallization (or crystallisation by cooling) process mother liquor, degree of supersaturation heterogeneity, the crystal size heterogeneity of growth.And the crystallization of membrane crystallization process and solvent concentrated be to complete at different device, there is not the inhomogenous problem of mother liquor degree of supersaturation.
Summary of the invention
The present invention is intended to overcome prior art defect, and object is to provide a kind of method of membrane crystallization separation and purification erythritol.
For achieving the above object, the concrete steps of the technical solution used in the present invention are: erythritol crystalline mother solution is sent in membrane module, water in mother liquor opposite side at film after membrane distillation sees through film with the form of water vapor is condensed into liquid water, the crystalline mother solution that leaves membrane module is sent into crystallizer after being concentrated and reaching supersaturation, erythritol crystal is fluidized suspension growth in circulation crystallization mother liquor, the crystalline mother solution on crystallizer upper strata carries out internal recycle through being pumped into membrane module, erythritol crystalline product is drawn by crystallizer bottom, solid-liquid separation, be drying to obtain erythritol crystal.
Described erythritol crystalline mother solution refers to fermented erythritol liquor after pre-treatment (thalline separation, ion-exchange, membrane filtration and decolouring) or the solution after the water-soluble rear elimination solid insoluble of erythritol crude product.
Described membrane module is hydrophobic hollow fiber membrane module.
Described crystallizer is fluidized-bed crystallizer.
Owing to adopting technique scheme, the present invention compared with prior art has following positively effect:
(1) method of membrane crystallization separation and purification erythritol involved in the present invention, adopt the concentrated erythritol crystalline mother solution of hollow fiber film assembly, without crystalline mother solution being heated to boiling, just can make water in mother liquor see through fenestra and reach hypersaturated state with the form of water vapour, effectively reduce erythritol evaporative crystallization or cooling and crystallizing process operation energy consumption.
(2) method of membrane crystallization separation and purification erythritol involved in the present invention, the degree of supersaturation of crystallization operation produces in membrane module, and crystal growth is positioned at fluidized-bed crystallizer, crystal is fluidized suspension in circulation crystallization mother liquor, for crystal growth provides good condition, and the existing size classification effect of fluidized-bed crystallizer has avoided again adding seeding, can grow granularity crystal greatly and uniformly.
Embodiment
Below in conjunction with embodiment, the invention will be further described, not the restriction to its protection domain.
embodiment 1
A kind of method of membrane crystallization separation and purification erythritol, its concrete steps are: the erythritol crystalline mother solution of 40 ~ 80 ℃ is sent in membrane module, water in mother liquor opposite side at film after membrane distillation sees through film with the form of water vapor is condensed into liquid water, the crystalline mother solution that leaves membrane module is sent into crystallizer after being concentrated and reaching supersaturation, erythritol crystal is fluidized suspension growth in circulation crystallization mother liquor, the crystalline mother solution on crystallizer upper strata carries out internal recycle through being pumped into membrane module, erythritol crystalline product is drawn by crystallizer bottom, solid-liquid separation, be drying to obtain erythritol crystal.
Described erythritol crystalline mother solution refers to the fermented erythritol liquor after pre-treatment (thalline separation, ion-exchange, membrane filtration and decolouring).
Described membrane module is hydrophobic hollow fiber membrane module.
Described crystallizer is fluidized-bed crystallizer.
embodiment 2
A method for membrane crystallization separation and purification erythritol, its concrete steps are:
The present embodiment is except described dissolved agent methyl alcohol, and all the other are with embodiment 1.
Claims (4)
1. the method for a membrane crystallization separation and purification erythritol, it is characterized in that, specifically complete according to the following steps: erythritol crystalline mother solution is sent in membrane module, water in mother liquor opposite side at film after membrane distillation sees through film with the form of water vapor is condensed into liquid water, the crystalline mother solution that leaves membrane module is sent into crystallizer after being concentrated and reaching supersaturation, erythritol crystal is fluidized suspension growth in circulation crystallization mother liquor, the crystalline mother solution on crystallizer upper strata carries out internal recycle through being pumped into membrane module, erythritol crystalline product is drawn by crystallizer bottom, solid-liquid separation, be drying to obtain erythritol crystal.
2. the method for membrane crystallization separation and purification erythritol according to claim 1, it is characterized in that, described erythritol crystalline mother solution refers to fermented erythritol liquor after pre-treatment (thalline separation, ion-exchange, membrane filtration and decolouring) or the solution after the water-soluble rear elimination solid insoluble of erythritol crude product.
3. the method for membrane crystallization separation and purification erythritol according to claim 1, is characterized in that, described membrane module is hydrophobic hollow fiber membrane module.
4. the method for membrane crystallization separation and purification erythritol according to claim 1, is characterized in that, described crystallizer is fluidized-bed crystallizer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310694042.5A CN103709008A (en) | 2013-12-18 | 2013-12-18 | Method for separating and purifying erythritol by membrane crystallization |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201310694042.5A CN103709008A (en) | 2013-12-18 | 2013-12-18 | Method for separating and purifying erythritol by membrane crystallization |
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| CN103709008A true CN103709008A (en) | 2014-04-09 |
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| CN201310694042.5A Pending CN103709008A (en) | 2013-12-18 | 2013-12-18 | Method for separating and purifying erythritol by membrane crystallization |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106748657A (en) * | 2016-11-30 | 2017-05-31 | 山东福田药业有限公司 | A kind of processing method of fermented erythritol liquor |
| CN106831337A (en) * | 2017-04-17 | 2017-06-13 | 武汉科技大学 | A kind of method of the continuous dissolved membrane crystallization of antierythrite |
| CN106946656A (en) * | 2017-04-17 | 2017-07-14 | 武汉科技大学 | A kind of continuous oscillation stream membrane crystallization method of antierythrite |
| CN106946655A (en) * | 2017-04-17 | 2017-07-14 | 武汉科技大学 | A kind of continuous anti-dissolved membrane crystallization method of antierythrite |
| CN111704637A (en) * | 2020-06-28 | 2020-09-25 | 南京工业大学 | Method for refining nucleotide by adopting membrane distillation crystallization |
| CN114685248A (en) * | 2022-03-24 | 2022-07-01 | 吉林中粮生化有限公司 | Method for producing erythritol crystals |
Citations (4)
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|---|---|---|---|---|
| CN101270372A (en) * | 2008-04-15 | 2008-09-24 | 中国石油化工股份有限公司 | Concentration method for sugar liquid in cellulose alcoholic fermentation |
| CN102154383A (en) * | 2010-12-29 | 2011-08-17 | 保龄宝生物股份有限公司 | Method for producing phycite by using corn meal |
| CN102839202A (en) * | 2012-09-26 | 2012-12-26 | 山东福田药业有限公司 | Method for processing erythritol fermentation liquor |
| CN102992957A (en) * | 2012-12-13 | 2013-03-27 | 武汉科技大学 | Solvent-out crystallization method of erythritol |
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2013
- 2013-12-18 CN CN201310694042.5A patent/CN103709008A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101270372A (en) * | 2008-04-15 | 2008-09-24 | 中国石油化工股份有限公司 | Concentration method for sugar liquid in cellulose alcoholic fermentation |
| CN102154383A (en) * | 2010-12-29 | 2011-08-17 | 保龄宝生物股份有限公司 | Method for producing phycite by using corn meal |
| CN102839202A (en) * | 2012-09-26 | 2012-12-26 | 山东福田药业有限公司 | Method for processing erythritol fermentation liquor |
| CN102992957A (en) * | 2012-12-13 | 2013-03-27 | 武汉科技大学 | Solvent-out crystallization method of erythritol |
Non-Patent Citations (1)
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| 贾志谦: "《膜科学与技术基础》", 31 March 2012, article "膜蒸馏" * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106748657A (en) * | 2016-11-30 | 2017-05-31 | 山东福田药业有限公司 | A kind of processing method of fermented erythritol liquor |
| CN106831337A (en) * | 2017-04-17 | 2017-06-13 | 武汉科技大学 | A kind of method of the continuous dissolved membrane crystallization of antierythrite |
| CN106946656A (en) * | 2017-04-17 | 2017-07-14 | 武汉科技大学 | A kind of continuous oscillation stream membrane crystallization method of antierythrite |
| CN106946655A (en) * | 2017-04-17 | 2017-07-14 | 武汉科技大学 | A kind of continuous anti-dissolved membrane crystallization method of antierythrite |
| CN111704637A (en) * | 2020-06-28 | 2020-09-25 | 南京工业大学 | Method for refining nucleotide by adopting membrane distillation crystallization |
| CN114685248A (en) * | 2022-03-24 | 2022-07-01 | 吉林中粮生化有限公司 | Method for producing erythritol crystals |
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Application publication date: 20140409 |