CN103705200A - Gastrointestinal tract precancerous lesion non-invasive detection system based on wireless energy supply - Google Patents
Gastrointestinal tract precancerous lesion non-invasive detection system based on wireless energy supply Download PDFInfo
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Abstract
The invention provides a gastrointestinal tract non-invasive detection system based on wireless energy supply, and relates to the field of endoscopes. The gastrointestinal tract non-invasive detection system comprises a detection video capsule system, an extracorporeal wireless energy supply device and an extracorporeal image processing device. The detection video capsule system comprises a shell, an optical system, a double-circuit lighting system, a poor light video image sensor, a master control system, an image wireless sending device, a rectifying device and a wireless energy receiving three-dimensional coil, wherein the optical system, the double-circuit lighting system, the poor light video image sensor, the master control system, the image wireless sending device, the rectifying device and the wireless energy receiving three-dimensional coil are arranged in the shell. According to the system, the whole digestive tract can be accurately detected.
Description
Technical field
What the present invention relates to is the system in a kind of endoscope field, specifically a kind of gastrointestinal tract precancerous lesion noinvasive detection system based on wireless energy supply.
Background technology
Because work rhythm quickening, diet are uneven, cause the M & M of digestive tract disease increasingly to raise, digestive tract disease becomes the common a kind of disease that affects modern's health.Analyze to find according to statistics, digestive tract disease to becoming younger, hiddenization future development.The early discovery of digestive tract disease, early diagnosis and early treatment have very important effect to reduction cancer morbidity, mortality rate.
The visual detection of the digestive tract disease of implementing clinically mainly contains two kinds: gastroscope, intestinal mirror and the large class of white light capsule endoscope two.Gastroscope or intestinal mirror insert the detection of enforcement digestive tract disease from oral cavity and anus respectively, but owing to being subject to the restriction of gastroscope and intestinal mirror length, gastroscope can only detect the digestive tract disease at stomach and duodenum position, intestinal mirror can only detect the digestive tract disease below colon, therefore gastroscope and intestinal mirror cannot detect the disease at small intestinal position, in gastroscope, intestinal mirror testing process, may there is the risk that causes stomach wound, intestinal wound simultaneously, in testing process, can bring huge misery to patient.White light capsule endoscope detects and belongs to noinvasive detection method, after patient's oral capsule endoscope, can implement the detection of digestive tract disease, can not bring discomfort or painful sensation to patient, the power supply mode of existing capsule more and more adopts the mode of wireless energy power supply, can meet the demand that improves medical diagnosis on disease accuracy rate and detect all-digestive tract image.But being converted into malignant cell, alimentary canal mucous membrane normal cell to experience a plurality of steps, precancerous lesion is the incubation period of cancer, reach five, six years its incubation period, precancerous lesion patient is not cancer patient, because the exhausted major part of their lesions position is heterocyst, so be easy to cure, and it is the same to return to Healthy People.It is no matter the detection mode of traditional gastroscope, intestinal mirror or white light capsule endoscope, the video image that all can only diagnose out pernicious canceration to occur, diagnosis is less than the abnormal image of Precancerous Lesion, cannot fundamentally realize early discovery and the early treatment of digestive tract disease, thereby reduce the M & M of digestive tract disease.
Through the retrieval of prior art is found, Chinese patent literature CN1493250, open day 2004-05-05, recorded a kind of device of using endoscope to diagnose precancer affection, comprise light source, light path system, endoscope and Circuits System, light source comprises exciting light and cold light source, wherein in light path system, cold light source and exciting light enter respectively the port of endoscope's light guide bundles by a fibre bundle, be irradiated to tested biological tissue, after the low light level CCD reception signal that the tested White-light image signal of tested biological tissue reflection is closely connected with port with tested primary fluorescence picture signal Jing Yu endoscope, by holding wire, be connected to Circuits System and carry out image demonstration, the tested hypofluorescence signal of tested biological tissue reflection is spread out of to Circuits System and carries out spectrum demonstration from the hypofluorescence fibre bundle of going out in the pincers hole of endoscope by a branch of.But the prior art is compared its shortcomings and deficiencies and is to adopt this technology to adopt the structure of dragging line formula with the present invention, be subject to the restriction of length, can not meet the demand of clinical all-digestive tract medical diagnosis on disease
Chinese patent literature CN102160774, open day 2011-08-24, recorded a kind of video image capsule system of wireless energy supply of technical field of medical instruments, comprise: capsule system, external wireless energy supply device and external image processing apparatus, capsule system is positioned at digestive tract and gathers digestive tract environment information, external image processing apparatus is connected with wireless mode with capsule system and transmits capsule video information and export with graphics mode, and external wireless energy supply device provides energy to capsule system in alternating magnetic field mode.But the prior art is compared its shortcomings and deficiencies and is that this technology only adopts white light cold light source with the present invention, can not realize the detection of precancerous lesion, thus the M & M of reduction digestive tract disease.
Summary of the invention
The present invention is directed to prior art above shortcomings, a kind of gastrointestinal tract precancerous lesion noinvasive detection system based on wireless energy supply is provided, thereby realizes all-digestive tract precancerous lesion Accurate Diagnosis, reduce the M & M of carninomatosis.
The present invention is achieved by the following technical solutions, the present invention includes: precancerous lesion detects video capsule system, external wireless energy supply device and external image processing apparatus, wherein:
Described precancerous lesion detects video capsule system and comprises: shell and be arranged at optical system wherein, two-way illuminator, low light level video image sensors, master control system, image wireless dispensing device, fairing and wireless energy receive three dimensional coils, wherein: wireless energy receives three dimensional coils and receives the alternating magnetic field being sent by external wireless energy supply device, and be translated into AC electromotive force, fairing is converted into DC voltage by this AC electromotive force, and be respectively low light level video image sensors, two-way illuminator, optical system, master control system and image wireless dispensing device provide DC source, optical system is arranged at the end of shell and controls for low light level video image sensors provides optics to regulate, two-way illuminator provides white light source and exciting light sources for low light level video image sensors, low light level video image sensors obtains respectively White-light image and the fluoroscopic image of detected digestive tract wall from white light source and exciting light sources, this White-light image and fluoroscopic image are sent to external image processing apparatus by image wireless dispensing device respectively, master control system is connected with two-way illuminator and controls alternately changing of white light source and exciting light sources, be connected with low light level video image sensors and control the adjusting of its imaging parameters.
Described two-way illuminator comprises: be arranged at the some equally distributed near purple light excited radiant that optical system is unified the some equally distributed cold light source of side and is arranged at optical system opposite side, wherein: the position of each nearly purple light excited radiant and cold light source is alternate layout accordingly, the white light source that cold light source sends is irradiated to tested biological tissue, the tested White-light image of tested biological tissue reflection, and the exciting light sources that nearly purple light excited radiant sends is irradiated to tested biological tissue, the tested primary fluorescence image of tested biological tissue reflection is obtained by low light level video image sensors respectively, white light cold light source adopts the paster white light LEDs of 4 0402 encapsulation, near ultraviolet light source adopts the 365nm near ultraviolet LED of 4 3020 encapsulation, the intensity of light source meets the requirement of low light image sensor to luminous power.Make illuminator especially near ultraviolet light source to dragging the demand of linear light cable.…
Described optical system comprises: optics bulb, varifocal optical lens, and wherein optics bulb is placed in the end of shell, guarantees that the light of the measured object in positive and negative 90 ° of the place ahead is not obstructed; Varifocal optical lens is placed in the place ahead of the photosurface of low light image sensor, guarantees that low light image sensor has the angle of visual field of 120 °, before assembling, regulates zoom aperture, makes low light image sensor have the optics depth of field of 3-40mm.
Described master control system comprises: light source replaces control part, video imaging control part, wherein: light source replaces control part and is connected with the analog switch of nearly purple light excited radiant break-make with control cold light source by data wire, realizes time and the dutycycle of the conversion of two kinds of light sources by the state of software control analog switch; Video imaging control part is connected with low light level video image sensors by SCCB bus protocol, adjust the parameter of the different depositors in low light image sensor, complete configuration and the control of low light level video image sensors, the image color that low light level video image sensors is collected under different illumination conditions is normal.
Described external wireless energy supply device comprises: external wireless energy transmitting coil and power-supply controller of electric, wherein: power-supply controller of electric becomes control signal by power source transition and is sent to external wireless energy transmitting coil, external wireless energy transmitting coil is transformed into alternating electromagnetic field by electric energy, wireless energy receives three dimensional coils and receives this alternating electromagnetic field, and alternating electromagnetic field is converted into alternating electromotive force again.
Described external image processing apparatus comprises: the real-time receiver module of external portable image and computer workstation, wherein: the real-time receiver module of external portable image and computer workstation receive respectively by image wireless dispensing device and send to external video signal, and video signal is converted into data image signal, and shows or store.
Technique effect
Compared with prior art, lesion detecting system can be broken away near ultraviolet light source because the reason of light intensity is to dragging the dependence of linear light fibre before gastrointestinal cancer of the present invention; Pass through software adjustment, control time and the dutycycle of white light cold light source and near ultraviolet light source, rapid scanning and detect precancerous lesion and early-stage cancer pathological changes, thus the transition process that optimum mutation changes pernicious canceration into cut off, reduce the M & M of carninomatosis.
Accompanying drawing explanation
Fig. 1 is operation principle schematic diagram of the present invention;
Fig. 2 is that precancerous lesion detects video capsule system structure schematic diagram;
Fig. 3 is the structural representation of master control system;
Fig. 4 is the diagnosis schematic diagram of precancerous lesion;
Fig. 5 is external wireless energy supply device structural representation;
Fig. 6 is external image processing apparatus schematic diagram.
The specific embodiment
Below embodiments of the invention are elaborated, the present embodiment is implemented take technical solution of the present invention under prerequisite, provided detailed embodiment and concrete operating process, but protection scope of the present invention is not limited to following embodiment.
As shown in Figure 1, the present embodiment comprises: the precancerous lesion that patient can swallow detects video image capsule system 13, external wireless energy supply device 14 and external image processing apparatus 15.Wherein, precancerous lesion detects white light and the fluoroscopic image of video image capsule system 13 Real-time Collection digestive tract inwalls, this picture signal belongs to video signal, by wireless communication mode, video signal transmitting is sent to outside patient body, external image processing apparatus 15 receives white light and the fluoroscopic image of digestive tract inwall, this video signal is converted into data image signal, directly be presented on the real-time receiver module of Portable external image, and can be kept on the real-time receiver module of Portable external image; Also can directly be received by computer workstation, this video signal is converted into data image signal, show and be kept on computer workstation.Computer workstation also can read and is kept at the image on the real-time receiver module of Portable external image.
As shown in Figure 2, the precancerous lesion of the present embodiment detection video image capsule system 13 comprises: optical system 1, two-way illuminator 2, low light level video image sensors 3, master control system 4, image wireless dispensing device 5, fairing 6, wireless energy receive three dimensional coils 7 and shell 8.
Shell 8 described in the present embodiment is cylindric, for ease of swallowing, shell 8 two ends are as far as possible close to hemispherical, smooth surface, and shell 8 requires to have good water resistance, guarantee that in digestive tract, liquid can not leak out to shell 8 inside, two-way illuminator 2 provides white light cold light source and nearly purple light excited radiant for low light level video image sensors 3, guarantee that capsule can photographic images in digestive tract, optical system 1 provides suitable optical imagery distance for low light level video image sensors 3, optical system 1, two-way illuminator 2 and low light level video image sensors 3 are arranged on capsule end, master control system 4 is connected in low light level video image sensors 3 by data wire, master control system can by data wire realize to white light cold light source and nearly purple light excited radiant alternately and configuration and the control of low light level video image sensors 3, the adjusting of realization to low light level video image sensors 3 imaging parameters, the video output of low light level video image sensors 3 is directly sent on image wireless dispensing device 5, the white light of the digestive tract inwall that image wireless dispensing device 5 can be exported video and the electromagnetic wave that fluoroscopic image changes certain frequency into are also sent to external.Wireless energy receives three dimensional coils 7 and receives the alternating magnetic field by external wireless energy transmitting coil transmitting, portion generates alternating electromotive force in coil, this alternating electromotive force is carried out filter rectification by fairing 6 and is generated DC source, and this DC source provides power supply for image wireless dispensing device 5, master control system 4, low light level video image sensors 3 and two-way illuminator 2.Optical system 1, two-way illuminator 2, low light level video image sensors 3, master control system 4, image wireless dispensing device 5, fairing 6 and wireless energy receive three dimensional coils 7 and are arranged in housing 8.
Described two-way illuminator 2 comprises: be arranged at the some equally distributed near purple light excited radiant that optical system is unified the some equally distributed cold light source of side and is arranged at optical system opposite side, wherein: the position of each nearly purple light excited radiant and cold light source is alternate layout accordingly, the white light source that cold light source sends is irradiated to tested biological tissue, the tested White-light image of tested biological tissue reflection, and the exciting light sources that nearly purple light excited radiant sends is irradiated to tested biological tissue, the tested primary fluorescence image of tested biological tissue reflection is obtained by low light level video image sensors respectively, white light cold light source adopts the paster white light LEDs of 4 0402 encapsulation, near ultraviolet light source adopts the 365nm near ultraviolet LED of 4 3020 encapsulation, the intensity of light source meets the requirement of low light image sensor to luminous power.Make illuminator especially near ultraviolet light source to dragging the demand of linear light cable.
In the present embodiment, cold light source is 4 White LEDs, and nearly purple light excited radiant is 4, layout alternate with white light LEDs.
Described optical system 1 comprises: ... optics bulb, varifocal optical lens, wherein optics bulb is placed in the end of shell, guarantees that the light of the measured object in positive and negative 90 ° of the place ahead is not obstructed; Varifocal optical lens is placed in the place ahead of the photosurface of low light image sensor, guarantees that low light image sensor has the angle of visual field of 120 °, before assembling, regulates zoom aperture, makes low light image sensor have the optics depth of field of 3-40mm.
As shown in Figure 3, described master control system 4 comprises: light source replaces control part, video imaging control part, wherein: light source replaces control part and is connected with the analog switch of nearly purple light excited radiant break-make with control cold light source by data wire, realizes time and the dutycycle of the conversion of two kinds of light sources by the state of software control analog switch; Video imaging control part is connected with low light level video image sensors by SCCB bus protocol, adjust the parameter of the different depositors in low light image sensor, complete configuration and the control of low light level video image sensors, the image color that low light level video image sensors is collected under different illumination conditions is normal.
As shown in Figure 4, the diagnostic method of the precancerous lesion of the present embodiment, from Fluorescence Mechanism, the generation of fluorescence is that in molecular structure, the variation of quantum state causes, different molecular structures produces different wavelength of fluorescence.As long as extraneous exciting light deexcitation cancerous tissue and the normal structure that has enough energy, the corresponding light quantum that oneself can absorb of their each self-absorptions, because light quantum is different, the energy discharging is also different, corresponding image color is also different thus, thereby just can differentiate normal structure and cancerous tissue accordingly.
As shown in Figure 5, external wireless energy supply device 14 comprises external wireless energy transmitting coil 10 and power-supply controller of electric 9, power-supply controller of electric 9 changes DC source the control signal of certain frequency into and is sent to external wireless energy transmitting coil 10, and external wireless energy transmitting coil 10 changes electric energy in the alternating magnetic field of certain frequency.
As shown in Figure 6, external image processing apparatus 15 comprises the real-time receiver module 11 of Portable external image and computer workstation 12, the real-time receiver module of Portable external image can receive white light and the fluoroscopic image information of the digestive tract inwall of wireless transmit in body in real time, and be presented on the display screen of the real-time receiver module 11 of Portable external image, also can be kept in the storage device of the real-time receiver module 11 of Portable external image, computer workstation 12 also has white light and the fluoroscopic image information of the digestive tract inwall of wireless transmit in real-time reception body, be presented on the screen of computer workstation, also can be kept on computer workstation.The function that the data that computer workstation 12 also can be preserved the real-time receiver module 11 of Portable external image are carried out playback.
Below in conjunction with accompanying drawing, the operation principle of this system is carried out to detailed description.Patient detects video image capsule system 13 by the precancerous lesion of swallowing, external wireless energy supply device 14 is started working, power-supply controller of electric 9 changes DC source the alternating signal of certain frequency into and is sent to external wireless energy transmitting coil 10, external wireless energy transmitting coil 10 changes electric energy in the alternating magnetic field of certain frequency, in this alternating magnetic field body, precancerous lesion detects wireless energy reception three dimensional coils 7 receptions of 13 li of video image capsule systems, portion produces alternating electromotive force in coil, this alternating electromotive force is rectified device 6 and carries out generating DC source after filter rectification, this DC source is to two-way illuminator 2, low light level video image sensors 3, master control system 4 and image wireless discharger 5.After master control system 4 powers on, realize replacing and low light level video image sensors 3 being configured to control of white light cold light source and nearly purple light excited light source, complete after configuration control, low light level video image sensors 3 starts normal work.After two-way illuminator 2 powers on and starts working, the precancerous lesion that has optical system one end is detected to video image capsule front end to be illuminated, the white light of digestive tract wall and fluoroscopic image are imaged in low light level video image sensors 3 by optical system 2, low light level video image sensors 3 generates the video signal of digestive tract wall white light and fluoroscopic image, this video signal is directly sent on image wireless discharger 5, by image wireless discharger 5, video signal is converted into the electromagnetic wave of certain frequency and is sent to outside patient body.Sending to external video signal is received by external image processing apparatus 15, there are two kinds of receive modes: when using the real-time receiver module 11 of Portable external image, the real-time receiver module 11 of Portable external image can be by the video signal receiving, video signal is converted into data image signal, be presented on screen, be kept on the storage device of itself simultaneously; When using computer workstation 12, computer workstation 12 is the video signal receiving, and this video signal is converted into data image signal, is presented in real time on computer screen, is stored on computer screen simultaneously.Computer workstation 12 also possesses and reads and the data image signal of the real-time receiver module of playback Portable external image 11 storages.
Claims (6)
1. the gastrointestinal tract noinvasive detection system based on wireless energy supply, it is characterized in that, comprise: detect video capsule system, external wireless energy supply device and external image processing apparatus, wherein: described detection video capsule system comprises: shell and be arranged at optical system wherein, two-way illuminator, low light level video image sensors, master control system, image wireless dispensing device, fairing and wireless energy receive three dimensional coils, wherein: wireless energy receives three dimensional coils and receives the alternating magnetic field being sent by external wireless energy supply device, and be translated into AC electromotive force, fairing is converted into DC voltage by this AC electromotive force, and be respectively low light level video image sensors, two-way illuminator, optical system, master control system and image wireless dispensing device provide DC source, optical system is arranged at the end of shell and controls for low light level video image sensors provides optics to regulate, two-way illuminator provides white light source and exciting light sources for low light level video image sensors, low light level video image sensors obtains respectively White-light image and the fluoroscopic image of detected digestive tract wall from white light source and exciting light sources, this White-light image and fluoroscopic image are sent to external image processing apparatus by image wireless dispensing device respectively, master control system is connected with two-way illuminator and controls alternately changing of white light source and exciting light sources, be connected with low light level video image sensors and control the adjusting of its imaging parameters.
2. system according to claim 1, it is characterized in that, described two-way illuminator comprises: be arranged at the some equally distributed near purple light excited radiant that optical system is unified the some equally distributed cold light source of side and is arranged at optical system opposite side, wherein: the position of each nearly purple light excited radiant and cold light source is alternate layout accordingly, the white light source that cold light source sends is irradiated to tested biological tissue, the tested White-light image of tested biological tissue reflection, and the exciting light sources that nearly purple light excited radiant sends is irradiated to tested biological tissue, the tested primary fluorescence image of tested biological tissue reflection is obtained by low light level video image sensors respectively, white light cold light source adopts the paster white light LEDs of 4 0402 encapsulation, near ultraviolet light source adopts the 365nm near ultraviolet LED of 4 3020 encapsulation, the intensity of light source meets the requirement of low light image sensor to luminous power.
3. system according to claim 1 and 2, is characterized in that, described optical system comprises: optics bulb, varifocal optical lens, and wherein optics bulb is placed in the end of shell, guarantees that the light of the measured object in positive and negative 90 ° of the place ahead is not obstructed; Varifocal optical lens is placed in the place ahead of the photosurface of low light image sensor, guarantees that low light image sensor has the angle of visual field of 120 °, before assembling, regulates zoom aperture, makes low light image sensor have the optics depth of field of 3-40mm.
4. system according to claim 3, it is characterized in that, described master control system comprises: light source replaces control part, video imaging control part, wherein: light source replaces control part and is connected with the analog switch of nearly purple light excited radiant break-make with control cold light source by data wire, realizes time and the dutycycle of the conversion of two kinds of light sources by the state of software control analog switch; Video imaging control part is connected with low light level video image sensors by SCCB bus protocol, adjust the parameter of the different depositors in low light image sensor, complete configuration and the control of low light level video image sensors, the image color that low light level video image sensors is collected under different illumination conditions is normal.
5. system according to claim 3, it is characterized in that, described external wireless energy supply device comprises: external wireless energy transmitting coil and power-supply controller of electric, wherein: power-supply controller of electric becomes control signal by power source transition and is sent to external wireless energy transmitting coil, external wireless energy transmitting coil is transformed into alternating electromagnetic field by electric energy, wireless energy receives three dimensional coils and receives this alternating electromagnetic field, and alternating electromagnetic field is converted into alternating electromotive force again.
6. according to the system described in claim 4 or 5, it is characterized in that, described external image processing apparatus comprises: the real-time receiver module of external portable image and computer workstation, wherein: the real-time receiver module of external portable image and computer workstation receive respectively by image wireless dispensing device and send to external video signal, and video signal is converted into data image signal, and shows or store.
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| CN104382547A (en) * | 2014-11-18 | 2015-03-04 | 上海交通大学 | Wearable wireless energy transmission equipment for capsule endoscope |
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