CN103656738A - Novel vitreous body filler and preparation method thereof - Google Patents
Novel vitreous body filler and preparation method thereof Download PDFInfo
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- CN103656738A CN103656738A CN201310678097.7A CN201310678097A CN103656738A CN 103656738 A CN103656738 A CN 103656738A CN 201310678097 A CN201310678097 A CN 201310678097A CN 103656738 A CN103656738 A CN 103656738A
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- vitreous body
- body filler
- preparation
- novel
- novel vitreous
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Abstract
The invention discloses novel vitreous body filler and a preparation method thereof. The novel vitreous body filler is flowable viscous liquid and comprises liquid paraffin and glycerin. The preparation method comprises the following steps: mixing 10-20ml of liquid paraffin and 20-30ml of glycerin, and carrying out autoclaved sterilization, thus obtaining the novel vitreous body filler. The novel vitreous body filler has the beneficial effects that the novel vitreous body filler has a retina restoration effect, stable inertia, optical transparency and small biological compatibility and can be directly injected in the operation.
Description
technical field:
The present invention relates to a kind of preparation field of vitreous body implant, relate in particular to a kind of ophthalmology vitreous body implant preparation field.
technical background:
Vitreous body implant implantation is used for the treatment of the reattachment of retina after the vitreous body enucleation of complicated retinal detachment.Vitreous chamber implant is the indispensable material for the treatment of complicated retinal detachment, and choosing packing material is the key of successful surgery, also the impact great on having of prognosis, complication.
From reported first in 1911, at vitreous chamber, inject air repairing retina and depart from so far, people find desirable vitreous substitute always constantly.Think that at present desirable vitreous substitute should have following characteristic: 1. water white transparency, avirulence, no antigen; 2. surface tension is large, can push up and press irregular surface; 3. proportion is low, can push up the side's of pressing retinal hole, or proportion is greater than water, ceasma that can the side of depressing, gravity top; 4. there is not emulsifying or dispersion; 5. viscosity is suitable, is convenient to inject or sucking-off.
Since within 1962, using silicone oil treatment detachment of retina, silicone oil approaches vitreous body with refractive index, has the advantages such as good optical transparence, toxicity are low, long action time, becomes the vitreous chamber implant of at present conventional complicated retinal detachment.Though many complicated retinal detachment persons' vision has been saved in the application of silicone oil, the postoperative complication of silicone oil has also affected the recovery of Postoperative visual acuity to a certain extent, has limited the application of silicone oil.Other also have gas filler etc., but also due to operation inconvenience, and fail extensively to promote.
summary of the invention:
Goal of the invention: design a kind of novel glass body implant, have reattachment of retina biocompatibility little, physicochemical property is stable, the feature of fluent material.
Technical scheme:
The invention provides a kind of novel glass body implant and preparation method thereof.Technical scheme is that liquid paraffin 10-20ml and glycerol 20-30ml are mixed, and autoclaving, obtains.
Accompanying drawing explanation
Accompanying drawing 1 vitreous body implant injection model figure.1. vitreous body implant ascending pipe; 2. gently manage; 3. vitreous body.
useful benefit:
Vitreous body implant prepared by the present invention, has reattachment of retina effect, stable inertia, optical transparence, and biocompatibility is little, the feature that operation can directly be injected.
the specific embodiment:
embodiment 1:liquid paraffin 10ml and glycerol 30ml are mixed, and autoclaving, obtains.
embodiment 2:liquid paraffin 20ml and glycerol 20ml are mixed, and autoclaving, obtains.
Claims (3)
1. a novel glass body implant, is characterized in that: be the thick liquid of the shape that flows.
2. a novel glass body implant, is characterized in that: liquid paraffin and glycerol, consist of.
3. novel glass body implant preparation method: it is characterized in that: liquid paraffin 10-20ml and glycerol 20-30ml are mixed, and autoclaving, obtains.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310678097.7A CN103656738A (en) | 2013-12-13 | 2013-12-13 | Novel vitreous body filler and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310678097.7A CN103656738A (en) | 2013-12-13 | 2013-12-13 | Novel vitreous body filler and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103656738A true CN103656738A (en) | 2014-03-26 |
Family
ID=50296291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310678097.7A Pending CN103656738A (en) | 2013-12-13 | 2013-12-13 | Novel vitreous body filler and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103656738A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001070132A2 (en) * | 2000-03-20 | 2001-09-27 | Biosphere Medical, Inc. | Injectable and swellable microspheres for dermal augmentation |
| CN201734718U (en) * | 2010-08-10 | 2011-02-09 | 王宁利 | Body position monitor after silicone oil injection surgery |
| CN103202742A (en) * | 2012-01-14 | 2013-07-17 | 上海市第一人民医院 | Hand held type silicone oil pumping kit |
-
2013
- 2013-12-13 CN CN201310678097.7A patent/CN103656738A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001070132A2 (en) * | 2000-03-20 | 2001-09-27 | Biosphere Medical, Inc. | Injectable and swellable microspheres for dermal augmentation |
| CN201734718U (en) * | 2010-08-10 | 2011-02-09 | 王宁利 | Body position monitor after silicone oil injection surgery |
| CN103202742A (en) * | 2012-01-14 | 2013-07-17 | 上海市第一人民医院 | Hand held type silicone oil pumping kit |
Non-Patent Citations (1)
| Title |
|---|
| 段聪 等: "硅油在玻璃体视网膜手术中的应用进展", 《医学综述》 * |
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Application publication date: 20140326 |