CN103585718B - A kind of all solid state collapsible intracavity and frequency yellow orange laser intravascular disease therapeutic equipment - Google Patents
A kind of all solid state collapsible intracavity and frequency yellow orange laser intravascular disease therapeutic equipment Download PDFInfo
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Abstract
The invention discloses a kind of all solid state collapsible intracavity and frequency yellow orange laser intravascular disease therapeutic equipment, including the first pump light source and the second pump light source, described first pump light source is connected with described first Transmission Fibers, described first Transmission Fibers is connected with the first optical coupling part, the side of described first optical coupling part is disposed with the first input cavity mirror, first gain medium and the first double-colored catadioptric mirror, one end of described first double-colored catadioptric mirror is and frequency crystal, the other end is the second double-colored catadioptric mirror, described and frequency crystal side is the chamber mirror that is all-trans, described second pump light source is connected with the second Transmission Fibers, it is disposed with the second optical coupling part between described second Transmission Fibers and described second double-colored catadioptric mirror, second input cavity mirror and the second gain medium.Use technical solution of the present invention, have that volume is little, lightweight, compact conformation, all solidstate are air-cooled, power consumptive province and a feature such as be easy to carry；Improve pump power, decrease side effect.
Description
Technical field
The present invention relates to semiconductor laser pumping all-solid state laser technology, laserresonator designing technique, intracavity and frequency technology, skin dynamic cooling technology and laser medical beauty treatment technology, be specifically related to a kind of all solid state collapsible intracavity and frequency yellow orange laser intravascular disease therapeutic equipment.
Background technology
Cutaneous vacular lesion includes vascular malformation and the big class of hemangioma two, common have nevus flammeus, strawberry hemangioma, telangiectasis, rosacea, varicose veins of the lower extremity etc., each position of whole body body surface can be betided, in addition to causing cosmetic defect to patient, it is also possible to cause corresponding dysfunction.Traditional Therapeutic Method has Drug therapy, liquid nitrogen cryotherapy, injection sclerosants, blood vessel ligation treatment and surgical operation etc., the invasive treatment of these non-selectivities is relatively big to normal dermal tissue insult, is often difficult to the complication accepted with the patient such as cicatrix, pigment alteration.
Along with laser technology provides effective means in the application of medical domain, the treatment for vascular disease of the skin.The laser of specific wavelength is pyrolyzed principle by selective light, act on the hemoglobin in lesion vessels, lesion vessels is made to be pyrolyzed, absorb, disappear, reach to treat vascular lesion and do not damage around tissue and skin and without the purpose of cicatrization, be to treat that vascular lesions is maximally efficient at present and the method that has no side effect.
Along with the development of semiconductor laser, all solid state laser of this laser pump (ing) also begins to be applied to the treatment of cutaneous vacular lesion.As wavelength is in the laser of the 532nm all solid state laser of green light band can be by hemoglobin good absorption, the setting of the treatment time width of continuous laser can thermal relaxation time dermovascular with adult close, these features make this laser become treatment vascular lesions first-selected therapeutic equipment.Although the absorptance of the HbO2 Oxyhemoglobin of 532nm wavelength is higher, melanic absorptance is the highest, the green laser of so 532nm is only applicable to the treatment of the thinner blood vessel in skin superficial face, is also more suitable for the treatment of the skin surface vascular conditions of the less white race of dermal melanin.In order to increase the treatment degree of depth of veins beneath the skin, generally use the semiconductor laser therapeutic of the infrared band of longer wavelengths of 808nm, 940nm, 980nm and 1064nm, but the absorptance of the hemoglobin of this wave band is relatively low, for thinner blood vessel, the light major part of this wave band passes through, and by the skin absorption of surrounding.
The yellow orange optical band of wavelength 577nm is an absworption peak of oxygen and hemoglobin, as the yellow orange light of 585nm and the green glow of 532nm have identical hemoglobin absorption coefficient, but melanic absorption is only the half of 532nm green glow, therefore it is more suitable for non-white race and is positioned under skin the treatment of the thin vascular conditions of some deeply.The laser therapeutic apparatus of yellow orange optical band mainly uses 585nm and the 595nm pulsed dye laser therapeutic instrument of flash lamp pumping at present.But dye laser have poor stability, dye degradation and toxic, energy expenditure is high, poor stability etc. so that the design of dye laser is extremely complex, bulky.Simultaneously because the peak power of pulse laser is the highest, this laser therapy vascular disease of the skin is used to be easy to cause the side effect such as purpura.
Summary of the invention
For overcoming deficiency of the prior art, the present invention provides a kind of all solid state collapsible intracavity and frequency yellow orange laser intravascular disease therapeutic equipment.
For realizing above-mentioned technical purpose, reaching above-mentioned technique effect, the present invention is achieved through the following technical solutions:
A kind of all solid state collapsible intracavity and frequency yellow orange laser intravascular disease therapeutic equipment, including the first pump light source and the second pump light source, described first pump light source is connected with described first Transmission Fibers, described first Transmission Fibers is connected with the first optical coupling part, the side of described first optical coupling part is disposed with the first input cavity mirror, first gain medium and the first double-colored catadioptric mirror, one end of described first double-colored catadioptric mirror is and frequency crystal, the other end is the second double-colored catadioptric mirror, described and frequency crystal side is the chamber mirror that is all-trans, described second pump light source is connected with the second Transmission Fibers, it is disposed with the second optical coupling part between described second Transmission Fibers and described second double-colored catadioptric mirror, second input cavity mirror and the second gain medium.
Further, described second double-colored catadioptric mirror is also connected with fibre-coupled mirrors, described fibre-coupled mirrors is connected with the 3rd Transmission Fibers, described 3rd Transmission Fibers and optical beam transformation camera lens are connected with treatment handle, described optical beam transformation camera lens has human skin with the front for the treatment of handle, the side of described human skin is provided with skin cooling system, is connected by synchronous control system between described first pump light source and described second pump light source.
Further, described first pump light source, described first Transmission Fibers, described first optical coupling part, described first input cavity mirror, described first gain medium, described first double-colored catadioptric mirror, described and frequency crystal and the described chamber mirror that is all-trans constitute the first semiconductor laser pumping system and the first folded resonator, and described first semiconductor laser pumping system and the first folded resonator can produce wavelength X1。
Further, described second pump light source, described second Transmission Fibers, described second optical coupling part, described second input cavity mirror, described second gain medium, described second double-colored catadioptric mirror, described and frequency crystal and the described chamber mirror that is all-trans constitute the second semiconductor laser pumping system and the second folded resonator, and described second semiconductor laser pumping system and the second folded resonator can produce wavelength X2。
Further, described and frequency crystal is placed on the intersection of combined type resonator cavity, and described combined type resonator cavity is made up of described first folded resonator and the second folded resonator, when wavelength is λ1Light beam and wavelength be λ2Light beam carried out Synchronization Control by described synchronous control system, by described and frequency crystal time, generation wavelength is λ3Yellowish orange and frequency laser, wavelength is λ3And frequency laser export outside described combined type resonator cavity by described second double-colored catadioptric mirror, described wavelength is λ3And frequency laser by described fibre-coupled mirrors, described 3rd Transmission Fibers and described optical beam transformation camera lens with treat handle, incide in the lesion vessels under described human skin.
Further, described fibre-coupled mirrors, described 3rd Transmission Fibers, described optical beam transformation camera lens and treatment handle, described skin cooling system and described synchronous control system constitute laser therapy and synchronous control system.
Further, it is λ at wavelength3And before and after frequency laser incides in the lesion vessels under described human skin, by described skin cooling system, described human skin is cooled down.
Compared with prior art, the method have the advantages that
Technical solution of the present invention, propose the collapsible intracavity of continuous output all-solid-state and the frequency yellow orange laser skin treating vascular diseases instrument using semiconductor laser technique, have that volume is little, lightweight, compact conformation, all solidstate are air-cooled, power consumptive province and a feature such as be easy to carry.Use intracavity and the frequency laser structure of composite construction, improve the pump power of laser instrument.Participate in two fundamental frequency light with frequency and use the collapsible laserresonator of different double-colored catadioptric mirrors, improve the conversion efficiency of laser instrument, under identical treatment area, the energy density close with flash lamp pumping pulsed dye laser treatment instrument can be obtained.Output time by modulation continuous laser is identical with the relaxation time of skin, it is thus achieved that the preferably therapeutic effect of vascular disease of the skin.
The present invention, compared with the pulsed dye laser treatment instrument of current existing 585nm and 595nm, will not produce that purpura that high impulse peak power causes and the poor stability of laser therapeutic apparatus, energy expenditure be high, poor stability and dyestuff are easily degenerated and have the problems such as toxicity.Meanwhile, compared with the present invention green laser therapeutic apparatus all solid state with current existing 532nm, the melanic absorption of human body skin is low, and penetrating of skin is deep, can treat deeper blood vessel and the vascular conditions of dark skin ethnic group under skin.
Described above is only the general introduction of technical solution of the present invention, in order to better understand the technological means of the present invention, and can be practiced according to the content of description, below with presently preferred embodiments of the present invention and coordinate accompanying drawing describe in detail as after.The detailed description of the invention of the present invention is shown in detail in by following example and accompanying drawing thereof.
Accompanying drawing explanation
Accompanying drawing described herein is used for providing a further understanding of the present invention, constitutes the part of the application, and the schematic description and description of the present invention is used for explaining the present invention, is not intended that inappropriate limitation of the present invention.In the accompanying drawings:
Fig. 1 is the internal structure schematic diagram of the present invention.
Label declaration in figure: 101, first pump light source, 122, first Transmission Fibers, 103, first optical coupling part, 104, first input cavity mirror, 105, first gain medium, 106, first double-colored catadioptric mirror, 107, with frequency crystal, 108, be all-trans chamber mirror, 201, second pump light source, 202, second Transmission Fibers, 203, second optical coupling part, 204, second input cavity mirror, 305, second gain medium, 206, second double-colored catadioptric mirror, 301, fibre-coupled mirrors, 302, 3rd Transmission Fibers, 303, optical beam transformation camera lens and treatment hands handle, 304, skin cooling system, 305, human skin, 306, synchronous control system.
Detailed description of the invention
Below with reference to the accompanying drawings and in conjunction with the embodiments, the present invention is described in detail.
nullWith reference to shown in Fig. 1，A kind of all solid state collapsible intracavity and frequency yellow orange laser intravascular disease therapeutic equipment，Including the first pump light source 101 and the second pump light source 201，Described first pump light source 101 is connected with described first Transmission Fibers 102，Described first Transmission Fibers 102 is connected with the first optical coupling part 103，The side of described first optical coupling part 103 is disposed with the first input cavity mirror 104，First gain medium 105 and the first double-colored catadioptric mirror 106，One end of described first double-colored catadioptric mirror 106 is and frequency crystal 107，The other end is the second double-colored catadioptric mirror 206，Described and frequency crystal 107 side is the chamber mirror 108 that is all-trans，Described second pump light source 201 is connected with the second Transmission Fibers 202，It is disposed with the second optical coupling part 203 between described second Transmission Fibers 202 and described second double-colored catadioptric mirror 206，Second input cavity mirror 204 and the second gain medium 205.
Further, described second double-colored catadioptric mirror 206 is also connected with fibre-coupled mirrors 301, described fibre-coupled mirrors 301 is connected with the 3rd Transmission Fibers 302, described 3rd Transmission Fibers 302 and optical beam transformation camera lens are connected with treatment handle 303, described optical beam transformation camera lens is provided with human skin 305 with the front for the treatment of handle 303, there is skin cooling system 304 on the side of described human skin 305, is connected by synchronous control system 306 between described first pump light source 101 and described second pump light source 201.
Further, described first pump light source 101, described first Transmission Fibers 102, described first optical coupling part 103, described first input cavity mirror 104, described first gain medium 105, described first double-colored catadioptric mirror 106, described and frequency crystal 107 and the described chamber mirror 108 that is all-trans constitute the first semiconductor laser pumping system and the first folded resonator, and described first semiconductor laser pumping system and the first folded resonator can produce wavelength X1。
Further, described second pump light source 201, described second Transmission Fibers 202, described second optical coupling part 203, described second input cavity mirror 204, described second gain medium 205, described second double-colored catadioptric mirror 206, described and frequency crystal 107 and the described chamber mirror 108 that is all-trans constitute the second semiconductor laser pumping system and the second folded resonator, and described second semiconductor laser pumping system and the second folded resonator can produce wavelength X2。
Further, described and frequency crystal 107 is placed on the intersection of combined type resonator cavity, and described combined type resonator cavity is made up of described first folded resonator and the second folded resonator, when wavelength is λ1Light beam and wavelength be λ2Light beam carried out Synchronization Control by described synchronous control system 306, by described and frequency crystal 107 time, generation wavelength is λ3Yellowish orange and frequency laser, wavelength is λ3And frequency laser arrived outside described combined type resonator cavity by described second double-colored catadioptric mirror 206 output, described wavelength is λ3And frequency laser by described fibre-coupled mirrors 301, described 3rd Transmission Fibers 302 and described optical beam transformation camera lens with treat handle 303, incide in the lesion vessels under described human skin 305.
Further, described fibre-coupled mirrors 301, described 3rd Transmission Fibers 302, described optical beam transformation camera lens and treatment handle 303, described skin cooling system 304 and described synchronous control system 306 constitute laser therapy and synchronous control system.
Further, it is λ at wavelength3And before and after frequency laser incides in the lesion vessels under described human skin 305, by described skin cooling system 304, described human skin 305 is cooled down.
The principle of the present invention:
First continuous output semiconductor laser pump (ing) system and the second continuous output semiconductor laser pump (ing) system are simultaneously emitted by pump light under the Pulse Width Control of synchronous control system 306, the first gain medium 105 in pumping the first folded resonator and the second gain medium 205 in the second folded resonator respectively, it is λ that the first gain medium 105 and the second gain medium 205 produce wavelength the most simultaneously1It is λ with wavelength2Fundamental frequency light；Described wavelength is λ1It is λ with wavelength2Fundamental frequency light simultaneously by the non-linear of the intersection of the first folded resonator and the second folded resonator and frequency crystal 107 time, produce that to meet the wavelength of preservation of energy condition be λ3And frequency laser；Described wavelength is λ3And the wavelength of frequency laser between the yellow orange optical band of 560nm to 600nm；Described wavelength is λ3Yellow orange laser by inciding the Ink vessel transfusing under treated human body skin after the beam Propagation of laser therapeutic system and conversion, by endovascular hemoglobin absorption, reach to treat the purpose of vascular disease of the skin；Described yellow orange laser by the spot diameter after the beam Propagation of laser therapeutic system and conversion between 0.3mm to 10mm；The Pulse Width Control time of described synchronous control system 306 is close with the hot relaxation of human body skin, works continuously between 0.5ms to 1s；Described laser therapeutic system includes a dynamic cooling system i.e. skin cooling system 304；Described dynamic cooling system is controlled by synchronous control system 306, cooling liquid is sent with after laser therapy impulse ejection before laser therapy impulse ejection, when cooling liquid gasifies, absorb the heat of treated skin surface, it is to avoid infringement to human body skin during treatment.
Embodiment one:
Similar with Fig. 1: wherein the first pump light source 101 uses the fiber coupled laser diode array that wavelength is 880nm of output continuously, peak power output 60W；The core diameter of the first Transmission Fibers 102 is 400 microns, has the optical fiber interface of SMA905；First pump light source 101 carries out temperature control by semiconductor cooler, uses fin and fan cooling；First optical coupling part 103 is two planoconvex lens, focal length 20mm, and convex surface is staggered relatively, prepares the anti-reflection film of 880nm at its logical bright finish；The pump beam incidence surface of the first input cavity mirror 104 prepares the antireflective film of 880nm, and another side preparation is high thoroughly and the high anti-multilayer dielectric film of 1342nm to 880nm anti-reflection, 1064nm；Gain medium 105 is YVO4+Nd:YVO4Ionic bond and laser crystal, use Nd:YVO4Crystal4 F 3/2Arrive4 I 13/2The 1342nm spectral line of transition, 1342nm antireflective film is prepared at the two ends of gain medium 105；First double-colored catadioptric mirror 106 uses plane mirror, and its 1342nm fundamental frequency light plane of incidence prepares 45oIncident lower 1342nm is high anti-, the high saturating multilayer dielectric film of 1064nm and 593.5nm, and another side prepares the high saturating multilayer dielectric film of 1064nm and 593.5nm；Using lbo crystal with frequency crystal 107, produce the yellow orange light cutting of 593.5nm by 1064nm Yu 1342nm and frequency, cutting angle is θ=90o, φ=2.6o, two logical bright finish of lbo crystal prepare the anti-reflection film of 1064nm, 1342nm and 593.5nm；The chamber mirror 108 that is all-trans uses plano-concave mirror, and concave surface prepares the high-reflecting film of 1064nm, 1342nm and 593.5nm；Second pump light source 201 uses the fiber coupled laser diode array that wavelength is 808nm of output continuously, output 60W；The core diameter of the second Transmission Fibers 202 is 400 microns, has the optical fiber interface of SMA905；Second pump light source 201 carries out temperature control by semiconductor cooler, uses fin and fan cooling；Second optical coupling part 203 is two planoconvex lens, focal length 20mm, and convex surface is staggered relatively, prepares the anti-reflection film of 808nm at its logical bright finish；The pump beam incidence surface of the second input cavity mirror 204 prepares the antireflective film of 808nm, another side preparation anti-multilayer dielectric film high to 808nm anti-reflection and 1064nm；Second gain medium 205 is YVO4+Nd:YVO4Ionic bond and laser crystal, use Nd:YVO4Crystal4 F 3/2Arrive4 I 11/2The 1064nm spectral line of transition, 1064nm antireflective film is prepared at crystal two ends；Second double-colored catadioptric mirror 206 uses plane mirror, and a face prepares 45oThe multilayer dielectric film that incident lower 1064nm is high anti-and 593.5nm height is saturating, another side prepares the high saturating multilayer dielectric film of 593.5nm；Fibre-coupled mirrors 301 uses monolithic plano-convex mirror, logical optical surface to prepare 593.5nm anti-reflection film；3rd Transmission Fibers 302 uses the optical fiber of core diameter 400 microns, a length of 1.5m；In optical beam transformation camera lens and treatment handle 303, optical beam transformation camera lens uses two panels lens, and lens lead to bright finish prepares 593.5nm anti-reflection film, and the front end face for the treatment of handle has spike, contacts with the treated human skin 305 that contacts；Synchronous control system 306 is made up of a piece of single-chip microcomputer, two D/A digital to analog converters, a RS232 serial line interface, two analog-modulated interfaces and two impulse modulation interfaces and other peripheral circuit and Software in Single Chip Microcomputer Control etc., two of which analog-modulated interface and two impulse modulation interfaces are connected with the driving power supply of the first pump light source 1-1 and the second pump light source 2-1 respectively, and RS232 serial line interface is connected with display screen or the control computer of therapeutic instrument.When after display screen or the parameter of other computer input treatment and instruction, by the parameter needed for the input treatment of RS232 serial line interface to single-chip microcomputer, single-chip microcomputer controls the first pump light source 101 and pump power of the second pump light source 201 respectively by two D/A digital to analog converters and analog-modulated interface, controls the first pump light source 101 and pulse working time of the second pump light source 201 by impulse modulation interface simultaneously.nullFirst pump light source 101 and the second pump light source 201 are according to the pump power set and pulse working time synchronous pump the first gain medium 105 and the second gain medium 205，Produce the fundamental frequency light of 1342nm and 1064nm respectively，And the 1064nm collapsible laser resonance intracavity vibration formed with the chamber mirror 108 that is all-trans at the collapsible laserresonator of 1342nm being made up of input cavity mirror 104 and the chamber mirror 108 that is all-trans and input cavity mirror 204 respectively，When 1342nm fundamental frequency light and 1064nm fundamental frequency light simultaneously by and during crystal LBO frequently，Produce 593.5nm and frequency yellow orange laser，After being exported by the second double-colored catadioptric mirror 206，By in the 3rd Transmission Fibers 302 that fibre-coupled mirrors 301 focuses on，The 593.5nm yellow orange laser exported by the 3rd Transmission Fibers 302 is converted to treat required spot size with treatment handle 303 by optical beam transformation lens，Ink vessel transfusing under the human body skin 305 at the spike center focusing on treatment handle，By the hemoglobin absorption in lesion vessels，Lesion vessels is made to be pyrolyzed、Absorb、Disappear，Reach to treat the purpose of vascular lesion.Before the treatment starts, by Single-chip Controlling skin cooling system 304, treated skin is sprayed 30ms, the pump power that wavelength is 880nm and 808nm that single-chip microcomputer is sent by simulation control Interface Controller pump light source 101 and 201 is 60W, it is 20W by the yellow orange light of the 593.5nm of the second double-colored catadioptric mirror output, it is 40ms by Pulse Width Control Interface Controller pulse laser continuous launch time, the energy inciding skin surface is 0.8J, inciding the spot diameter on skin after optical beam transformation by optical beam transformation camera lens and treatment handle is 4mm, the energy density being applied in skin heart is 6.3J/cm2, spot size pulse width and incident energy density when treating with usual 595nm pulsed dye laser treatment instrument are similar.It is to export continuously in 40ms owing to the laser of the present invention exports, rather than generally 4 pulses of pulsed dye therapeutic instrument or 8 pulses, there is no high peak power, purpura will not be produced, also there is no the problems such as the poor stability of pulsed dye laser therapeutic instrument, dye degradation toxic, energy expenditure is high, poor stability.
Embodiment two:
Similar with Fig. 1: wherein the first pump light source 101 uses the fiber coupled laser diode array that wavelength is 880nm of output continuously, output 80W；The core diameter of the first Transmission Fibers 102 is 400 microns, has the optical fiber interface of SMA905；First pump light source 101 carries out temperature control by semiconductor cooler, uses fin and fan cooling；First optical coupling part 103 is two planoconvex lens, focal length 20mm, and convex surface is staggered relatively, prepares the anti-reflection film of 880nm at its logical bright finish；The pump beam incidence surface of the first input cavity mirror 104 prepares the antireflective film of 880nm, and another side preparation is high thoroughly and the high anti-multilayer dielectric film of 1319nm to 880nm anti-reflection, 1064nm；Gain medium 105 is Nd:YAG laser crystal, uses4 F 3/2Arrive4 I 13/2The 1319nm spectral line of transition, 1319nm antireflective film is prepared at the two ends of gain medium 105；First double-colored catadioptric mirror 106 uses plane mirror, and its 1319nm fundamental frequency light plane of incidence prepares 45oIncident lower 1319nm is high anti-, the high saturating multilayer dielectric film of 1064nm and 589nm, and another side prepares the high saturating multilayer dielectricity film preparation of 1064nm and 589nm；Using lbo crystal with frequency crystal 107, produce the yellow orange light cutting of 589nm by 1064nm Yu 1319nm and frequency, cutting angle is θ=90o, φ=3.4o, two logical bright finish of lbo crystal 107 prepare the anti-reflection film of 1064nm, 1319nm and 589nm；The chamber mirror 108 that is all-trans uses plano-concave mirror, and concave surface prepares the high-reflecting film of 1064nm, 1319nm and 589nm；Second pump light source 201 uses the fiber coupled laser diode array that wavelength is 808nm of output continuously, output 60W；The core diameter of the second Transmission Fibers 202 is 400 microns, has the optical fiber interface of SMA905；Second pump light source 201 carries out temperature control by semiconductor cooler, uses fin and fan cooling；Second optical coupling part 203 is two planoconvex lens, focal length 20mm, and convex surface is staggered relatively, prepares the anti-reflection film of 808nm at its logical bright finish；The pump beam incidence surface of the second input cavity mirror 204 prepares the antireflective film of 808nm, another side preparation anti-multilayer dielectric film high to 808nm anti-reflection and 1064nm；Gain medium 205 is YVO4+Nd:YVO4Ionic bond and laser crystal, use Nd:YVO4Crystal4 F 3/2Arrive4 I 11/2The 1064nm spectral line of transition, 1064nm antireflective film is prepared at the two ends of gain medium 205；Second double-colored catadioptric mirror 206 uses plane mirror, and a face all prepares 45oThe multilayer dielectric film that incident lower 1064nm is high anti-and 589nm height is saturating, another side prepares the high saturating multilayer dielectric film of 589nm；Fibre-coupled mirrors 301 uses monolithic plano-convex mirror, logical optical surface to prepare 589nm anti-reflection film；3rd Transmission Fibers 302 uses the optical fiber of core diameter 400 microns, a length of 1.5m；In optical beam transformation camera lens and treatment handle 303, optical beam transformation camera lens uses two panels lens, and lens lead to bright finish prepares 589nm anti-reflection film, and the front end face for the treatment of handle has spike, contacts with the treated human skin 305 that contacts；Synchronous control system 306 is made up of a piece of single-chip microcomputer, two D/A digital to analog converters, a RS232 serial line interface, two analog-modulated interfaces and two impulse modulation interfaces and other peripheral circuit and Software in Single Chip Microcomputer Control etc., two of which analog-modulated interface and two impulse modulation interfaces driving power supply with the first pump light source 1-1 and the second pump light source 201 respectively is connected, and RS232 serial line interface is connected with display screen or other computer of therapeutic instrument.When after display screen or the parameter of other computer input treatment and instruction, by the parameter needed for the input treatment of RS232 serial line interface to single-chip microcomputer, single-chip microcomputer is by D/A digital to analog converter and analog-modulated Interface Controller the first pump light source 101 and the pump power of the second pump light source 201, by impulse modulation Interface Controller the first pump light source 101 and the pulse working time of the second pump light source 201.nullFirst pump light source 101 and the second pump light source 201 are according to the pump power set and pulse working time synchronous pump the first gain medium 105 and the second gain medium 205，Produce the fundamental frequency light of 1319nm and 1064nm respectively，And the 1064nm laser resonance intracavity vibration formed with the chamber mirror 108 that is all-trans at the 1319nm laserresonator being made up of with the chamber mirror 108 that is all-trans input cavity mirror 104 and input cavity mirror 204 respectively，When 1319nm fundamental frequency light and 1064nm fundamental frequency light simultaneously by and during crystal LBO frequently，Produce 589nm and frequency yellow orange laser，After the yellow orange laser that both direction produces is exported by the second double-colored catadioptric mirror 206，By in the 3rd Transmission Fibers that fibre-coupled mirrors 3-1 focuses on，Be converted to treat required spot size by optical beam transformation lens by the 589nm yellow orange laser of the 3rd Transmission Fibers output，Focus on the Ink vessel transfusing under the human body skin 305 at spike center，By the hemoglobin absorption in lesion vessels，Lesion vessels is made to be pyrolyzed、Absorb、Disappear，Reach to treat the purpose of vascular lesion.Before the treatment starts, by Single-chip Controlling skin cooling system 304, human body skin 305 is sprayed 30ms, make skin temperature at about 0 degree Celsius, the pump power that wavelength is 880nm and 808nm that single-chip microcomputer is sent by simulation control Interface Controller pump light source 101 and 201 is respectively 80W and 60W, it is 20W by the yellow orange light of the 589nm of the second double-colored catadioptric mirror output, it is 40ms by Pulse Width Control Interface Controller pulse laser continuous launch time, the energy inciding skin surface is 0.8J, inciding the spot diameter on skin after optical beam transformation by optical beam transformation camera lens and treatment handle is 4mm, the energy density being applied in skin heart is 6.3J/cm2。
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.All within the spirit and principles in the present invention, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.
Claims (4)
1. an all solid state collapsible intracavity and frequency yellow orange laser intravascular disease
Disease therapeutic apparatus, it is characterised in that include the first pump light source (101) and
Second pump light source (201), described first pump light source (101) and the
One Transmission Fibers (102) connect, described first Transmission Fibers (102) with
First optical coupling part (103) connects, described first optical coupled portion
The side of part (103) is disposed with the first input cavity mirror (104), the
One gain medium (105) and the first double-colored catadioptric mirror (106), institute
The one end stating the first double-colored catadioptric mirror (106) is and frequency crystal (107),
The other end is the second double-colored catadioptric mirror (206), described and frequency crystal (107)
Side be the chamber mirror (108) that is all-trans, described second pump light source (201)
It is connected with the second Transmission Fibers (202), described second Transmission Fibers (202)
And it is disposed with the second light between described second double-colored catadioptric mirror (206)
Learn coupling unit (203), the second input cavity mirror (204) and the second laser
Gain media (205), described second double-colored catadioptric mirror (206) also with light
Fine coupling mirror (301) connects, described fibre-coupled mirrors (301) and the 3rd
Transmission Fibers (302) connects, described 3rd Transmission Fibers (302) and light
Shu Bianhuan camera lens is connected with treatment handle (303), described optical beam transformation mirror
Head has human skin (305) with the front for the treatment of handle (303),
The side of described human skin (305) is provided with skin cooling system
(304), described first pump light source (101) and described second pump light
Connected by synchronous control system (306) between source (201), described the
One pump light source (101), described first Transmission Fibers (102), described
One optical coupling part (103), described first input cavity mirror (104), institute
State the first gain medium (105), described first double-colored catadioptric mirror (106),
Described and frequency crystal (107) and the described chamber mirror (108) that is all-trans constitute the
Semiconductor laser pump (ing) system and the first folded resonator, and described
Semiconductor laser pump (ing) system and the first folded resonator can produce ripple
Long λ1, described second pump light source (201), described second Transmission Fibers (202),
Described second optical coupling part (203), described second input cavity mirror (204),
Described second gain medium (205), described second double-colored catadioptric mirror
(206), described and frequency crystal (107) and the described chamber mirror (108) that is all-trans
Constitute the second semiconductor laser pumping system and the second folded resonator,
And described second semiconductor laser pumping system and the second folded resonator
Wavelength X can be produced2。
All solid state collapsible intracavity the most according to claim 1 and frequency are yellow
Orange laser intravascular disease therapeutic equipment, it is characterised in that described and frequency crystal
(107) intersection of combined type resonator cavity it is placed on, and described compound
Formula resonator cavity is collapsible humorous by described first folded resonator and second
Shake chamber composition, when wavelength is λ1Light beam and wavelength be λ2Light beam by institute
State synchronous control system (306) and carry out Synchronization Control, by described and frequency
During crystal (107), generation wavelength is λ3Yellowish orange and frequency laser, wavelength
For λ3And frequency laser by described second double-colored catadioptric mirror (206) output arrive
Outside described combined type resonator cavity, described wavelength is λ3And frequency laser pass through institute
State fibre-coupled mirrors (301), described 3rd Transmission Fibers (302) and institute
State optical beam transformation camera lens and treatment handle (303), incide described human body skin
In lesion vessels under skin surface (305).
All solid state collapsible intracavity the most according to claim 2 and frequency are yellow
Orange laser intravascular disease therapeutic equipment, it is characterised in that described optical fiber couples
Mirror (301), described 3rd Transmission Fibers (302), described optical beam transformation mirror
Head and treatment handle (303), described skin cooling system (304) and institute
State synchronous control system (306) and constitute laser therapy and Synchronization Control system
System.
All solid state collapsible intracavity the most according to claim 2 and frequency are yellow
Orange laser intravascular disease therapeutic equipment, it is characterised in that be λ at wavelength3's
The pathological changes blood under described human skin (305) is incided with frequency laser
Before and after in pipe, by described skin cooling system (304) to institute
State human skin (305) to cool down.
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| CN201310536279.0A CN103585718B (en) | 2013-11-04 | 2013-11-04 | A kind of all solid state collapsible intracavity and frequency yellow orange laser intravascular disease therapeutic equipment |
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| CN105552697A (en) * | 2016-02-04 | 2016-05-04 | 长春光机医疗仪器有限公司 | Sum frequency laser and laser therapeutic instrument |
| CN110537925B (en) * | 2019-08-27 | 2021-05-28 | 河南大学 | Optical fiber leading-in type oxygen saturation detection device and method |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101820132A (en) * | 2010-04-13 | 2010-09-01 | 苏州生物医学工程技术研究所 | All solid-state medical double resonance intracavity sum frequency yellow light laser |
| CN102044838A (en) * | 2010-11-18 | 2011-05-04 | 苏州生物医学工程技术研究所 | Stimulated Raman sum frequency laser wavelength conversion device |
| CN203777519U (en) * | 2013-11-04 | 2014-08-20 | 中国科学院苏州生物医学工程技术研究所 | All-solid folding-type intracavity sum-frequency yellow-orange laser therapeutic instrument for vascular diseases |
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| JP4202730B2 (en) * | 2002-11-19 | 2008-12-24 | 株式会社トプコン | Solid state laser equipment |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101820132A (en) * | 2010-04-13 | 2010-09-01 | 苏州生物医学工程技术研究所 | All solid-state medical double resonance intracavity sum frequency yellow light laser |
| CN102044838A (en) * | 2010-11-18 | 2011-05-04 | 苏州生物医学工程技术研究所 | Stimulated Raman sum frequency laser wavelength conversion device |
| CN203777519U (en) * | 2013-11-04 | 2014-08-20 | 中国科学院苏州生物医学工程技术研究所 | All-solid folding-type intracavity sum-frequency yellow-orange laser therapeutic instrument for vascular diseases |
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