Background technology:
Skin ulcer, hinder these two kinds of serious illness and caused greatly injury and painful to the mankind, especially the injury that war brings is larger, the residual life funeral of the thousands of person, with one's family broken up, the mankind do not bow to two serious illness of skin ulcer wound, constantly all defeating by every means it, many active drugs have been there is at all times, for example: ancient prescription Chinese patent medicine: Yuzhen San, Anisodus carniolicoides C.Y.Wu et C.Chen, recuperating depleted YANG Yulong cream, gold are loose, YULU SAN, red medicine wet goods, but the Chinese patent medicine indication of great majority treatment skin ulcer wound is narrow, curative effect is general, and Western medicine antibiotic curative effect is undesirable and side effect is large.The present invention is to " skin ulcer wound " two disease determined curative effects, and instant effect, has the special effect of getting instant result.
The object of the present invention is to provide and a kind ofly there is treatment skin ulcer and hinder two diseases and have following advantage to be: that pain relieving is fast, hemostasis is fast, detumescence is fast, it is fast to draw out the pus, promoting tissue regeneration and ulcer healing closes up is fast, slight wound I degree, II degree do not stay cicatrix, malignant boil, severely injured disease alleviating to dwindle cicatrix, thereby reach, heal the wounded and rescue the dying, alleviate numerous patients' misery, race against time and accelerate good dose of the critical sick and wounded of rescue.
China is damage Standard Key now
One, the damage wound degree of depth is divided into three degree: I degree injures below epidermis, more than corium, injures blood capillary; II degree undermines below corium and connective tissue; III degree injures blood vessel, nerve, muscles and bones, internal organs internal organs official.
The general three degree quarterings that adopt of estimation of the extreme misery burn and scald degree of depth, the different degree of depth has different features.
I degree (erythema) degree of depth reaches horny layer of epidermis, and stratum germinativum exists; Pathology local vascular dilation, hyperemia, ooze out; Clinical manifestation: slightly red, swell and ache, heat, hyperesthesia, dry tack free is without blister; Agglutination is short, after 2-3 days, fully recovers without scar.
II degree (blister) degree of depth reaches high dermis, and part stratum germinativum exists; Pathology blood plasma oozes out, and amasss between epidermis and corium; Clinical manifestation: severe pain, hyperesthesia, have blister, after bubble skin peels off, visible wound surface evenly rubescent, moist, edema is obvious; Agglutination: 1-2 week recovery from illness, does not leave over cicatrix, has pigmentation.
III degree (eschar) degree of depth reaches skin holostrome, sometimes can reach subcutaneous tissue, muscle and skeleton; Pathology cutaneous necrosis, protein coagulation form eschar; Clinical manifestation: cutaneous pain disappears, inelastic, dry, without blister as hide-like, white, the sallow or carbonization of wax, can see the vein branch of subcutaneous thrombus obstruction, pulls off the feather of not bitterly, Rhizoma Imperatae is without normal anatomical structures; Agglutination: 2-4 is after week, the eschar formation granulation wound that comes off, and small size can be creeped and be healed by epithelium around, leaves over cicatrix; The slightly large person of area, needs skin-grafting to heal.
Two, burn surface area computing method: when burn surface area calculates, have concept three-dimensional, volume; Burned part is divided into: ,Yu dead zone, necrotic area, congested district, and three divides a word with a hyphen at the end of a line mutually; Malpractice, stasis of blood dead zone can develop into necrotic area; Otherwise, in time treatment (as blood circulation promoting and blood stasis dispelling etc.), stasis of blood dead zone also can transfer congested district to and fully recover.
1, Chinese rule of Nine: Zhe Shi China is after measured after a large amount of human bodies, the adult's surface area computing method obtaining.Method is: health each several part surface area is divided into 11 9 deciles, and head, face, cervical region are 9%; Two upper limb are 2 * 9%=18%; Before and after trunk, comprise that pudendum is 3 * 9%=27%; Two lower limb comprise that buttocks is 5 * 9%=45%.Pediatric head proportion is larger, and extremity are less, therefore to child's burn surface area, should calculate according to all ages and classes.
Surgical infection diagnostic point
1, furuncle and furunculosis
Furuncle is that the acute festering type of single hair follicle and affiliated sebaceous gland thereof infects, and often expands subcutaneous tissue to; The infection that is confined to hair follicle or sebaceous gland is respectively folliculitis and thylacitis; The two is usually expanded into furuncle; A plurality of and the furuncle that is dispersed in, or simultaneously or successively repeatedly occur in health person everywhere, be called furunculosis.The traditional Chinese medical science is called furuncle, and have furuncle, summer boil, damp and hot furuncle minute.
The pathogenic bacterium of [etiology and pathology] furuncle mostly are staphylococcus aureus and Staphylococcus albus.In the hair follicle of human body and sebaceous gland, conventionally have antibacterial to exist, when whole body and local resistance reduce, can cause infection, malnutrition, dysbolismus (as diabetes), overtired or local skin damage, unclean etc. is all risk factor.
Motherland's Chinese medicine is thought: primary disease exopathogenic factor pyretic toxicity invasion and attack are accumulate in skin, endogenous cause of ill interspaces of skin and muscles being loose, and just not anti-heresy and causing a disease, because pyretic toxicity gesture poly-ly forms red, the lesser tubercle that swells and comes to a head and be more called furuncle slow accumulateing; If occur in summer, extremely hot dry, antiperspirant rushes down not smooth, and because summer-heat must press from both sides wetly, heat-damp in summer resistance and skin, scorchingly hotly slightly contain and be called summer boil again; If usually insufficiency of the spleen, pyretic toxicity and damp are double holds under the arm, damp and hot accumulate poison fight knot touching, this heals that, is called damp and hot furuncle.
2, carbuncle
Carbuncle is that the acute festering type by a plurality of adjacent hair follicles and sebaceous gland infects, or is merged and formed by a plurality of furuncles, belongs to the traditional Chinese medical science " external carbuncle " scope.
[etiology and pathology]
The pathogenic bacterium of carbuncle are mainly staphylococcus aureuses, infect Chang Congyi hair follicle bottom and start, because skin is thick, infection can only spread to subcutaneous tissue along the weak fat columns of resistance, along deep fascia, to surrounding, spread, invade contiguous fatty post, more upwards import follicle group into and form carbuncle.
Motherland's Chinese medicine is thought: primary disease is many because of surfeit greasy and surfeit flavour, so that spleen fortune loses strong, damp and hot interior life, or because of hyperactivity of fire caused by deficiency of YIN again the scorchingly hot damp of diseases caused by exogenous pathogenic factor cause a disease; In > >, says in < <: anxious dysphagia related to QI disorder is angry, liver-fire rebellion thus Rong Wei becomes estranged, stagnation of nutrient QI, contrary in meat reason, be raw " carbuncle.”
Surgical common disease criterion of therapeutical effect
Outside infection: furuncle and furunculosis [healing] union of wounded skin.[improvement] sent out furuncle carbuncle again and reduced, and symptom alleviates.[not healing] furuncle and phyma rises one after another, and can not control.
Carbuncle [healing] the not local lump of suppuration person disappears, and after bursting, wound healing is without General Symptoms.[improvement] General Symptoms disappears, and local symptom alleviates, and lump is stiff to be dwindled.[not healing] part and General Symptoms increase the weight of.
Acute cellulitis's [healing] General Symptoms disappears, local woanded surface healing.[improvement] General Symptoms disappears substantially, and wound is healing completely not.
Erysipelas [healing] part and General Symptoms disappear, and hemogram is normal.[improvement] General Symptoms disappears, and local symptom does not disappear entirely.
Acute abscess [healing] abscess disappears, wound healing, and General Symptoms disappears.After the drain of [improvement] Abscess incision, wound heals substantially, and General Symptoms disappears.[not healing] part and General Symptoms fail to control.
Tetanus [healing] General Symptoms and the disappearance of twitching, without complication.[improvement] General Symptoms takes a turn for the better, and wound is healing completely not.[not healing] General Symptoms has no improvement.
Rabies [healing] symptom and sign disappearance (primary disease is mostly dead).
Traumatic hemothorax [healing] stopped bleeding, clinical symptom disappearance, x-ray checks that thoracic cavity is without hydrops, lung expansion is good.
Transference cure after traumatic asphyxia [healing] treatment, cardio-pulmonary function is normal.
Damage, burn [healing] 1, superficial burns wound surface (general designation of shallow II degree and the dark partially shallow wound surface of II degree) healing completely; 2, deep burn wound (general designation of the partially dark and deepⅢdegree burns of dark II degree) healing substantially, residue wound surface is dispersed in and not in blocks, can heal and not make skin graft by changing dressings.3, the life of complication [healing] Severe Burn Patients can be taken care of oneself substantially, without severe deformities and dysfunction.[improvement] (1), superficial burns wound surface heal not yet completely, but without General Symptoms, can be outpatient service processor; (2) the most of healing of deep burn wound, without obvious General Symptoms, residue wound surface is little, but still need skin-grafting or other operative treatments; (3) there are severe deformities and dysfunction, can't take care of oneself.
Burn systemic infection [healing] General Symptoms disappears, and blood antibacterial, fungal culture are negative continuously, and traumatic infection is controlled, visceral complications recovery from illness.[improvement] General Symptoms and visceral complications take a turn for the better, and traumatic infection is controlled.
Chilblain [healing] transference cure, wound healing.
Main handbook: 1, < < disease clinical diagnosis and criterion of therapeutical effect > > 2, < < disease of tcm Standardization of diagnosis and curative effect > > 3, < < common disease diagnosis basis and criterion of therapeutical effect > >.
Summary of the invention:
Solution of the present invention is: based on motherland's medical science to skin ulcer, hinder understanding and the Therapeutic Principle of two diseases and complication mechanism, as follows with reference to filtering out natural Chinese medicine function in modern pharmacological research achievement ,Cong motherland medical treasure-house: Olibanum: promoting blood circulation and stopping pain, detumescence and promoting granulation are regulated the flow of vital energy; Myrrha: reducing swelling and alleviating pain, promoting tissue regeneration and ulcer healing, loose blood and dissolving stasis; Radix Ampelopsis: heat-clearing and toxic substances removing, eliminating carbuncle removing obstruction for relieving pain; The Pseudobulbus Bletillae (Rhizoma Bletillae): astringing to arrest bleeding, muscle-growing and detumescence; Catechu: heat clearing and damp drying, expelling pus and promoting granulation; Radix Sanguisorbae: cooling blood for hemostasis, removing toxic substances sore; Sanguis Draxonis: blood-activating analgetic, expelling pus and promoting granulation; Radix Notoginseng: loose blood hemostasis, subduing swelling and relieving pain, kidney invigorating and YANG supporting, raising immunity; Crinis Carbonisatus: hemostasis repercussive, nourishing YIN diuresis; Pyritum: eliminating stasis to stop pain, reunion of fractured tendons and bones; Oleum Sesami: separate all poison; Borneolum Syntheticum: the merit that inducing resuscitation, clearing away heat to improve acuity of vision, treatment skin infection are not held back after swelling and ache, bursting.The present invention by above ten simply natural Chinese medicines material to melt be a stove, make its function stack, networking effect, bring out the best in each other, complementation is coordinated, refinforce each other, thereby reach good dose of the effect of getting twice the result with half the effort.
Its technical characterictic of technical solution of the present invention is that by weight " part " compatibility has following raw materials according combination: 8-24 parts of Radix Sanguisorbaes, 6-26 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 6-20 parts of Radix Notoginseng, 6-20 parts of Sanguis Draxonis, Olibanum 6-20 part, 6-20 parts of Myrrhas, 6-20 parts of Crinis Carbonisatus, 6-20 parts of Pyritums, 6-20 parts of Radix Ampelopsis, 6-20 parts, catechu, Borneolum Syntheticum 0.5-1.5 part, Oleum Sesami (Oleum sesami) are made right amount of auxiliary materials.
Concrete enforcement
Making medicine preferred weight ratio range of the present invention is: 8-20 parts of Radix Sanguisorbaes, Pseudobulbus Bletillae (Rhizoma Bletillae) 6-16 part, 6-16 parts of Radix Notoginseng, 6-16 parts of Sanguis Draxonis, Olibanum 6-16 part, Myrrha 6-16 part, 6-16 parts of Crinis Carbonisatus, 6-16 parts of Pyritums, 6-16 parts of Radix Ampelopsis, catechu 6-16 part, 0.5-1.5 parts of Borneolum Syntheticums, Oleum Sesami (Oleum sesami) are made adjuvant substrate with appropriate.
Clinical drug of the present invention is used result to show following advantage: the pure natural medical that the present invention selects is raw material, and each component meets pharmaceutical control law regulation, utilizes the comprehensive function treatment skin ulcer of each taste Chinese medicine to hinder two diseases nontoxic to human body; For the therapeutic effect of proof medicine of the present invention to " skin ulcer wound ", the present invention is through 100 routine system clinical observations and select similar " skin ulcer wound " patient's 100 examples of the medical history state of an illness, age, sex and former therapeutic scheme: (1) injury by sword or axe I degree: 27 people are with medicated powder of the present invention or the external application of ointment treatment of making, 12 people after seven days wound healing without infection; II degree is hindered 15 people, and 8 people wound healing after treating 12 days is intact, and 7 people infect, fully recover without scar through treating all healing nothings in 14 days-16 days; Operate on operation 50 people, operation is respectively: prostatitis 11 people, ligation sterilization operation 39 people, 12 male, 27 women, above patient with operation, performs the operation and first takes medicated powder of the present invention, every day 2-3 times the previous day, each 10 grams of warm waters of swallowing are sent down, and clothes are left hospital to recovery from illness always.Intact none example of 7 days wound healings of taking out stitches of man's corrective surgery infects; After female's corrective surgery, after 8-9 days, take out stitches, 27 female patients have two patient infections, and other 25 female patients all heal intact; Two female patient infections are treated, with external application of ointment of the present invention after 3 days wound healing intact.
Extreme misery is burnt: I degree is hindered 17 people (10 years old 5 people of child, 8 years old 3 people, adult 9 people) and all fully recovered without scar after 2-3 days through applying ointment of the present invention; Partially shallow 8 people of II degree wound fully recover without scar after one week through chrisma.
Skin infection: fiery furuncle and phyma pain 6 people fully recover after seven days through external application ointment of the present invention.
[method for making] can be prepared into any dosage form on pharmaceutics by prior art by pharmacopeia routine fashion.
Preferred powder: material processing is qualified simply by above ten, weighing is assorted, is dried, powder becomes sieve mix homogeneously and get final product of superfine powder.
Beneficial effect function with cure mainly: heat-clearing and toxic substances removing, antiphlogistic and bactericidal, loose blood blood stasis dispelling, cooling blood for hemostasis, promoting blood circulation and stopping pain, detumescence and promoting granulation, the evacuation of pus of drawing out pus by applying a plaster to the affected part, reunion of fractured tendons and bones, dredging collateral reason wound, sore closing in etc.For incised wound operate on that operation, traumatic injury, traumatic hemorrhage congestion, fracture muscle damage, traumatic injury turn round frustrate swell and ache, do not close up for a long time after ulcer disease, traumatic infection, soft tissue injury, ulcer, the disease such as burn due to hot liquid or fire, the hemorrhoid of having blood in stool, ulcer sores toxic swelling, furuncle and phyma pain, chilblain.
[consumption usage] (1) operates on operation: adult measures every day 2 times, and each 10 grams, oral administration and externally all can.Child takes the circumstances into consideration decrement, warm water delivery service or honey and adjusts cream to take after mixing it with water.(2) burn due to hot liquid or fire: oral administration and externally is worked along both lines, one, two degree slight wound light externals, stick with paste with Oleum Sesami furnishing cream the affected part exposure formula of applying; Dark two degree are scalded Orally taken and externally wholistic therapy; During third degree burn infiltration, spreading medicated powder thin layer, then spray Oleum Sesami (little atomizers spray cleaning sterile), the time replacing as one sees fit of changing dressings in right amount, and dead flesh eschar coordinates surgical removal, and taking orally is that main external application is auxiliary.(3) traumatic injury and unexpected injury be take external as main, take orally as applying and deal with on the merits of each case.Allly outer in order to medicated powder and Oleum Sesami, be in harmonious proportion in right amount uniform stirring and become ointment pasty state in order to external; The appropriate Pressur hemostatic hoop of all wound medication powder spreading wounds encloses the healing of closing up.(4) furuncle toxic swelling be take external and is taken orally as auxiliary as main.(5) the tall and erect effect of chilblain external.(6) incised wound and various hemorrhage, ulcerate disease are splendid with oral administration and externally partner treatment effect.(7) disease such as various negative skin infection and erysipelas has different curative effects, and oral administration and externally all can.
[specification and package storage] powder: with the plastic bag of nontoxic aseptic cleaning, every bag contains ten grams of crude drug amounts, every ten packed cartons sealings (every bag of tolerance rate ± 2%).Leave the shady and cool place of aeration-drying in.
[quality and health] powder will make quality and health all up to standard qualified in strict accordance with pharmaceutical control and administration laws and regulations requirement.