CN103566011B - Traditional Chinese medicine composition for treating thromboangiitis obliterans and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating thromboangiitis obliterans and preparation method thereof Download PDFInfo
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- CN103566011B CN103566011B CN201210268129.1A CN201210268129A CN103566011B CN 103566011 B CN103566011 B CN 103566011B CN 201210268129 A CN201210268129 A CN 201210268129A CN 103566011 B CN103566011 B CN 103566011B
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Abstract
The invention discloses a traditional Chinese medicine composition for treating thromboangiitis obliterans, which comprises the following traditional Chinese medicine raw materials by weight: 5-10 parts of rhizoma atractylodis, 8-12 parts of pubescent holly roots, 3-10 parts of leech, 6-16 parts of wingystem veronicastrum herbs, 3-8 parts of cinnamon, 5-15 parts of gentrin knotweed, 6-12 parts of dandelion, 4-12 parts of ciliate desert-grass, 5-12 parts of arborvitae seeds, 6-15 parts of fructus cannabis, 4-12 parts of rhizoma corydalis, 4-12 parts of plantago, 4-12 parts of white peony roots, 4-12 parts of medicated leaven, 4-8 parts of haws, 5-12 parts of parasitic loranthus, 6-12 parts of salvia, 6-12 parts of angelica, 5-12 parts of caulis spatholobi, 6-12 parts of radix astragali, and 2-6 parts of licorice. The traditional Chinese medicine composition for treating thromboangiitis obliterans of the invention has the effects of regulating blood, washing blood, cleaning blood, discharging contaminates, removing stasis, expelling toxin, and relieving spasm, thus can recover blood vessel functions, enhance capabilities of elastic dilation and contraction, and reaches the purpose of treating vasculitis.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of thromboangiitis obliterans, and particularly a kind of take vegetable Chinese herbal medicine as the medicine of the treatment thromboangiitis obliterans that raw material is made.
Background technology
Thromboangiitis obliterans mainly invades limbs, from the Chinese point of view: the reason of primary disease is invasion cold-damp, and pyretic toxicity inside fire attack, battalion defends imbalance, malnutrition, and vigour is poor, and clear sun can not walk logical extremity, coagulation of QI-blood, caused by meridians obstruct is obstructed.Again because primary disease and cigarette (nicotine) drinks, medicine, wound are cold, spirit, endocrine disturbance are relevant, and vasculitic pathological change is that blood vessel produces spasm and causes angiodystrophia, vascellum tunica interna incrassation, muddy, finally cause blood to fasten formation, lumen of vessels is inaccessible, its symptom, and suffering limb is ice-cold, acid account, redness, shortness of breath and fatigue, cardiopalmus, dizzy, spirit is burnt tired; red urine; constipation due to dry stool, amyotrophy, toes variable color; water of suppurating during twinge; corrupt, wound is not healed, serious local necrosis; general malaise, causes amputation to disable.
Must to boil rear drinkable for the Chinese medicine of prior art treatment thromboangiitis obliterans, takes inconvenience and composition is unstable.
Summary of the invention
The object of the invention is to the above-mentioned deficiency overcoming prior art, provide a kind of and conveniently take and the Chinese medicine composition of the treatment thromboangiitis obliterans of stable components.
Treat a Chinese medicine composition for thromboangiitis obliterans, formula comprises the following raw material of Chinese medicine counted by weight:
Rhizoma Atractylodis 5-10 part, Radix Ilicis Pubescentis 8-12 part, Hirudo 3-10 part, Herba Veronicastri caulopteri 6-16 part, Cortex Cinnamomi 3-8 part, Rhizoma Polygoni Cuspidati 5-15 part, Herba Taraxaci 6-12 part, Herba pteridis vittatae 4-12 part, Semen Platycladi 5-12 part, Fructus Cannabis 6-15 part, Rhizoma Corydalis 4-12 part, Herba Plantaginis 4-12 part, Radix Paeoniae Alba 4-12 part, Massa Medicata Fermentata 4-12 part, Fructus Crataegi 4-8 part, Herba Taxilli 5-12 part, Radix Salviae Miltiorrhizae 6-12 part, Radix Angelicae Sinensis 6-12 part, Caulis Spatholobi 5-12 part, Radix Astragali 6-12 part, Radix Glycyrrhizae 2-6 part.
Preferably, the formula of the Chinese medicine composition of this treatment thromboangiitis obliterans comprises the following raw material of Chinese medicine counted by weight:
Rhizoma Atractylodis 5-8 part, Radix Ilicis Pubescentis 8-10 part, Hirudo 3-6 part, Herba Veronicastri caulopteri 6-10 part, Cortex Cinnamomi 3-4 part, Rhizoma Polygoni Cuspidati 5-8 part, Herba Taraxaci 6-10 part, Herba pteridis vittatae 4-8 part, Semen Platycladi 5-10 part, Fructus Cannabis 6-10 part, Rhizoma Corydalis 4-6 part, Herba Plantaginis 4-6 part, Radix Paeoniae Alba 4-6 part, Massa Medicata Fermentata 4-8 part, Fructus Crataegi 4-6 part, Herba Taxilli 5-8 part, Radix Salviae Miltiorrhizae 6-8 part, Radix Angelicae Sinensis 6-8 part, Caulis Spatholobi 5-6 part, Radix Astragali 6-10 part, Radix Glycyrrhizae 2-4 part.
More excellent, the Chinese medicine composition of this treatment thromboangiitis obliterans is made up of the following raw material of Chinese medicine counted by weight:
Rhizoma Atractylodis 5 parts, Radix Ilicis Pubescentis 8 parts, Hirudo 3 parts, Herba Veronicastri caulopteri 6 parts, Cortex Cinnamomi 3 parts, Rhizoma Polygoni Cuspidati 5 parts, Herba Taraxaci 6 parts, Herba pteridis vittatae 4 parts, Semen Platycladi 5 parts, Fructus Cannabis 6 parts, Rhizoma Corydalis 4 parts, Herba Plantaginis 4 parts, the Radix Paeoniae Alba 4 parts, Massa Medicata Fermentata 4 parts, Fructus Crataegi 4 parts, Herba Taxilli 5 parts, Radix Salviae Miltiorrhizae 6 parts, Radix Angelicae Sinensis 6 parts, Caulis Spatholobi 5 parts, Radix Astragali 6 parts, 2 parts, Radix Glycyrrhizae.
For producing the Chinese medicine composition of this treatment thromboangiitis obliterans, the present invention also comprises following production technology:
The preparation method of the Chinese medicine composition for the treatment of thromboangiitis obliterans of the present invention, comprises the following steps: add water all raw material of Chinese medicine steaming and decocting, and amount of water is 8-20 times of raw material of Chinese medicine weight, and decocting time is 2-5 hour, obtains fluid extract.
By the dry cream that fluid extract drying is less than 2% for the weight content of moisture, by broken for gained dried cream powder be 100 order dry powder, dry powder is incapsulated.
The dry cream that the weight content being moisture by fluid extract drying is less than 2%, is broken to 100 order dry powder, dry powder is pressed into lamellar by gained dried cream powder.
Compared with prior art, the present invention achieves following superior technique effect: act on treating blood disorders, wash blood, purify the blood, blowdown, blood stasis dispelling, toxin expelling, spasmolytic, makes blood vessel restore funcitons, strengthens elastic dilatation, contractility, reaches the vasculitic object for the treatment of.
Detailed description of the invention
Content of the present invention is described in detail below in conjunction with specific embodiment:
The formula of the Chinese medicine composition for the treatment of thromboangiitis obliterans of the present invention has multiple:
embodiment 1:
The Chinese medicine composition of the treatment thromboangiitis obliterans of the present embodiment is made up of the following raw material of Chinese medicine counted by weight:
Rhizoma Atractylodis 5 parts, Radix Ilicis Pubescentis 8 parts, Hirudo 3 parts, Herba Veronicastri caulopteri 6 parts, Cortex Cinnamomi 3 parts, Rhizoma Polygoni Cuspidati 5 parts, Herba Taraxaci 6 parts, Herba pteridis vittatae 4 parts, Semen Platycladi 5 parts, Fructus Cannabis 6 parts, Rhizoma Corydalis 4 parts, Herba Plantaginis 4 parts, the Radix Paeoniae Alba 4 parts, Massa Medicata Fermentata 4 parts, Fructus Crataegi 4 parts, Herba Taxilli 5 parts, Radix Salviae Miltiorrhizae 6 parts, Radix Angelicae Sinensis 6 parts, Caulis Spatholobi 5 parts, Radix Astragali 6 parts, 2 parts, Radix Glycyrrhizae.
embodiment 2:
Rhizoma Atractylodis 8 parts, Radix Ilicis Pubescentis 10 parts, Hirudo 6 parts, Herba Veronicastri caulopteri 10 parts, Cortex Cinnamomi 4 parts, Rhizoma Polygoni Cuspidati 8 parts, Herba Taraxaci 10 parts, Herba pteridis vittatae 8 parts, Semen Platycladi 10 parts, Fructus Cannabis 10 parts, Rhizoma Corydalis 6 parts, Herba Plantaginis 6 parts, the Radix Paeoniae Alba 6 parts, Massa Medicata Fermentata 8 parts, Fructus Crataegi 6 parts, Herba Taxilli 8 parts, Radix Salviae Miltiorrhizae 8 parts, Radix Angelicae Sinensis 8 parts, Caulis Spatholobi 6 parts, Radix Astragali 10 parts, 4 parts, Radix Glycyrrhizae.
embodiment 3:
Rhizoma Atractylodis 10 parts, Radix Ilicis Pubescentis 12 parts, Hirudo 10 parts, Herba Veronicastri caulopteri 16 parts, Cortex Cinnamomi 8 parts, Rhizoma Polygoni Cuspidati 15 parts, Herba Taraxaci 12 parts, Herba pteridis vittatae 12 parts, Semen Platycladi 12 parts, Fructus Cannabis 15 parts, Rhizoma Corydalis 12 parts, Herba Plantaginis 12 parts, the Radix Paeoniae Alba 12 parts, Massa Medicata Fermentata 12 parts, Fructus Crataegi 8 parts, Herba Taxilli 12 parts, Radix Salviae Miltiorrhizae 12 parts, Radix Angelicae Sinensis 12 parts, Caulis Spatholobi 12 parts, Radix Astragali 12 parts, 6 parts, Radix Glycyrrhizae.
The Chinese medicine composition for the treatment of thromboangiitis obliterans of the present invention adopts water extraction to carry out effective component extracting: add water all raw material of Chinese medicine steaming and decocting, and amount of water is 8-20 times of raw material of Chinese medicine weight, and decocting time is 2-5 hour, obtains fluid extract.
After obtaining fluid extract, then according to sell need be made as capsule, tablet or liquor:
If be made as capsule, comprise the following steps: the dry cream that the weight content being moisture by fluid extract drying is less than 2%; By broken for gained dried cream powder be 100 order dry powder, incapsulated by dry powder, every capsules weight is 0.25 gram.
If be made as tablet, comprise the following steps: the dry cream that the weight content being moisture by fluid extract drying is less than 2%; By broken for gained dried cream powder be 100 order dry powder, dry powder is pressed into lamellar, and every sheet weight is 0.25 gram.
If be made as liquor, then after only fluid extract drying need being concentrated, the liquor of joining for debita spissitudo loads in the bottle of 100cc.
When preparing the Chinese medicine composition for the treatment of thromboangiitis obliterans of the present invention, the drying means of employing can be the drying under reduced pressure of prior art, oven dry or spraying dry.
The usage of the Chinese medicine composition for the treatment of thromboangiitis obliterans of the present invention: every day 3 times, each 3, warm water is taken.
Traditional Chinese medicine composition for treating case 886 example for the treatment of thromboangiitis obliterans of the present invention, cure rate reaches 91.2%, and remaining symptom alleviates, and takes a turn for the better gradually.
Model case:
Patient: Li Meizhen, female, 55 years old, yiyang, hunan people, in August, 2004 suffered from vasculitis, once looks for several provincial hospitals to be diagnosed as vasculitis, need cut out limb.Household asks me to treat, and disease is seen, affected part, right lower limb lower limb thumb location is purplish red, edema of lower limbs, cold and hot all pains, has blood stasis speckle, fidgety, spirit is poor, on foot inconvenience, bed, deep-thready pulse, deep red tongue, with traditional Chinese medical science viewpoint, dialectical is blood stasis vasculitis.
By three courses for the treatment of, 10 days each courses for the treatment of, treat three courses for the treatment of continuously, check after three courses for the treatment of, local inflammation disappears, and pallial siphuncle disappears, and without any subjective symptoms, cures and within several years, no longer happens suddenly.
In medicine Radix Ilicis Pubescentis of the present invention, Fructus Crataegi, Herba Taxilli etc., green herbal medicine can amass with damp eliminating, the clear old poison of Ink vessel transfusing dirt, can to purify the blood, to wash blood.First bitter rear sweet when Compendium of Material Medica " Chinese medicine voluminous dictionary " " Radix Ilicis Pubescentis " all on the books eyesight-improving intelligence-developing, refreshment, steadily (falling) hypertension drink, delicate fragrance turbidity removal has a distinctive style, men and women, old and young often drink energy building body, health, convenience, nothing dirt, fully natural green removing toxic substances, toxin expelling are except malicious contamination thing, make blood peace and quiet, improve blood circulation and reach treatment vasculitis and the various cardiovascular and cerebrovascular disease of prevention.
Rhizoma Atractylodis have the effect of dirty dampness of dispelling; Radix Ilicis Pubescentis, Hirudo, Herba Veronicastri caulopteri can be removed all old poison and be amassed, scrubbing, removing toxic substances, toxin expelling, wash blood, purify the blood the effect making blood flow unimpeded, is the treasured of preventing and treating diseases health care; Cortex Cinnamomi warming YANG holds up the moon, makes negative and positive long mutually, balance; Hu Zhang, Herba Taraxaci, Herba pteridis vittatae energy anti inflammation and heat resolution, blood stasis dispelling, makes the red and swollen regressive effect in affected part, can also reach analgesic effect; Semen Platycladi, Fructus Cannabis can remove intestinal dryness accumulated in the stomach and intestine, bowel relieving intestine moistening, and noxious dampness is discharged from stool; Herba Plantaginis energy waterway, makes damp and hotly to discharge from urine; Rhizoma Corydalis has warm human body, dredging blood vessel analgesic efficacy; The Radix Paeoniae Alba, Massa Medicata Fermentata have suppressing the hyperactive liver spleen invigorating intercommunication effect, see the disease of liver, knowing the liver disease will be transmitted into the spleen, in the ban tonifying the spleen, can be soothing the liver, and spleen invigorating running improves, and improves microcirculation; Fructus Crataegi, Herba Taxilli purify the blood fat, blood fat reducing, cholesterol reducing effect; Radix Salviae Miltiorrhizae blood vessel dilating, promotes blood circulation and protects the heart; Caulis Spatholobi, Radix Angelicae Sinensis, Radix Astragali energy QI invigorating, to enrich blood, gas promoting the circulation of blood then row, blood is the important substance of nutrition human body, flow round without stopping follow row in arteries and veins, irrigate the vital organs of the human body, nourish extremity bones of the body collectively, impel blood to live and row stagnant, consolidate the righting effect of getting rid of evils.Radix Glycyrrhizae and middle priming reach affected part, reach and play the drug effect effect of curing the disease.
Above-mentioned embodiment understands protection scope of the present invention for helping, and is not intended to limit the scope of the invention.
Claims (4)
1. treat a Chinese medicine composition for thromboangiitis obliterans, it is characterized in that the Chinese medicine composition of this treatment thromboangiitis obliterans is made up of the following raw material of Chinese medicine counted by weight:
Rhizoma Atractylodis 5 parts, Radix Ilicis Pubescentis 8 parts, Hirudo 3 parts, Herba Veronicastri caulopteri 6 parts, Cortex Cinnamomi 3 parts, Rhizoma Polygoni Cuspidati 5 parts, Herba Taraxaci 6 parts, Herba pteridis vittatae 4 parts, Semen Platycladi 5 parts, Fructus Cannabis 6 parts, Rhizoma Corydalis 4 parts, Herba Plantaginis 4 parts, the Radix Paeoniae Alba 4 parts, Massa Medicata Fermentata 4 parts, Fructus Crataegi 4 parts, Herba Taxilli 5 parts, Radix Salviae Miltiorrhizae 6 parts, Radix Angelicae Sinensis 6 parts, Caulis Spatholobi 5 parts, Radix Astragali 6 parts, 2 parts, Radix Glycyrrhizae.
2. the preparation method of the Chinese medicine composition for the treatment of thromboangiitis obliterans according to claim 1, it is characterized in that comprising the following steps: add water all raw material of Chinese medicine steaming and decocting, amount of water is 8-20 times of raw material of Chinese medicine weight, and decocting time is 2-5 hour, obtains fluid extract.
3. the preparation method of the Chinese medicine composition for the treatment of thromboangiitis obliterans according to claim 2, characterized by further comprising following steps: the dry cream that the weight content being moisture by fluid extract drying is less than 2%, by broken for gained dried cream powder be 100 order dry powder, dry powder is incapsulated.
4. the preparation method of the Chinese medicine composition for the treatment of thromboangiitis obliterans according to claim 2, characterized by further comprising following steps: the dry cream that the weight content being moisture by fluid extract drying is less than 2%, gained dried cream powder is broken to 100 order dry powder, dry powder is pressed into lamellar.
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| CN201210268129.1A CN103566011B (en) | 2012-07-31 | 2012-07-31 | Traditional Chinese medicine composition for treating thromboangiitis obliterans and preparation method thereof |
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| CN103566011B true CN103566011B (en) | 2015-04-08 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105497654A (en) * | 2016-01-29 | 2016-04-20 | 丁云龙 | Traditional Chinese medicine for treating thromboangiitis obliterans |
| KR102040763B1 (en) * | 2017-10-27 | 2019-11-05 | 한약진흥재단 | Anti-thrombus agent comprising extract of Polygonum cuspidatum Sieb. et Zucc. and Cinnamomum cassia Blume |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1331989A (en) * | 2001-05-23 | 2002-01-23 | 郑国芃 | Chinese medicine for treating thromboangitis obliterans |
| CN101199657A (en) * | 2007-12-17 | 2008-06-18 | 郑海波 | Medicament for treating vasculitis |
| US20090196941A1 (en) * | 2005-11-10 | 2009-08-06 | Jose Angel Olalde Rangel | Synergistic Phytoceutical Compositions |
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2012
- 2012-07-31 CN CN201210268129.1A patent/CN103566011B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1331989A (en) * | 2001-05-23 | 2002-01-23 | 郑国芃 | Chinese medicine for treating thromboangitis obliterans |
| US20090196941A1 (en) * | 2005-11-10 | 2009-08-06 | Jose Angel Olalde Rangel | Synergistic Phytoceutical Compositions |
| CN101199657A (en) * | 2007-12-17 | 2008-06-18 | 郑海波 | Medicament for treating vasculitis |
Non-Patent Citations (3)
| Title |
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| 中医药治疗脱疽研究进展;高小明;《实用中医内科杂志》;20100131;第24卷(第1期);第44-45页 * |
| 中药复方治疗血栓闭塞性脉管炎用药分析;孙皎月;《海峡药学》;20101231;第22卷(第12期);第222-224页 尤其是第223页左栏表1、第1段、右栏第1段 * |
| 治疗三期Ⅱ级血栓闭塞性脉管炎33例报告;李廷来;《中医杂志》;19801231(第1期);第42-43页 尤其是第42页右栏第8-9段 * |
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