CN103550624A - Traditional Chinese medicine preparation for treating atherosclerosis and coronary heart disease - Google Patents
Traditional Chinese medicine preparation for treating atherosclerosis and coronary heart disease Download PDFInfo
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- CN103550624A CN103550624A CN201310524895.4A CN201310524895A CN103550624A CN 103550624 A CN103550624 A CN 103550624A CN 201310524895 A CN201310524895 A CN 201310524895A CN 103550624 A CN103550624 A CN 103550624A
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Abstract
The invention relates to a traditional Chinese medicine preparation for treating atherosclerosis and coronary heart disease. The traditional Chinese medicine preparation contains the following main raw materials in parts by weight: 30 parts of angelica, 15 parts of rhizoma Chuanxiong, 18 parts of white peony roots, 30 parts of malt, 12 parts of safflower, 12 parts of laminaria, 10 parts of peppermint, 30 parts of oxtongue and 30 parts of reed rhizomes. The traditional Chinese medicine preparation for treating atherosclerosis and coronary heart disease and a preparation method thereof, provided by the invention, have the aim that the traditional Chinese medicine preparation has good prevention and treatment effects on diseases, of which the usual manifestations can show symptoms, such as mental and physical deterioration, aortic atherosclerosis and coronary atherosclerosis and the like. The traditional Chinese medicine preparation provided by the invention can be prepared into any conventional oral-administration preparation, such as pills, powder, tablets, capsules and oral solutions, by adopting the conventional traditional Chinese medicine preparation methods.
Description
Technical field
The present invention relates to treat the Chinese medicine preparation of atherosclerosis and coronary heart disease, be specifically related to the Chinese medicine preparation of being made by several raw material of Chinese medicine compatibilities.
Background technology
In prior art, atherosclerosis is one group and is called in arteriosclerotic angiopathy the most common, most important a kind of.Be characterized in that ductus arteriosus wall thickens hardening, follows the string and tube chamber dwindles, because the lipid outward appearance of gathering is yellow medicated porridge sample, be therefore called atherosclerosis on endarterium.Mainly involve big-and-middle-sized tremulous pulse, its clinical manifestation mainly be take and is got involved the symptom of organ as main.Therapy (one) Drug therapy 1. is adjusted the patient of hypolipidemic medicine dyslipidemia, through above-mentioned dietary adjustments and attention, carry out physical exertion after 3 months, the horizontal person of miss the mark, should select and take that Statins reduces TC and LDL-C is main fat regulation medicine, other classes as special in shellfish, nicotinic acid class, placed separately dose of cholic acid, unsaturated fatty acid etc.2. the medicine that antiplatelet drug antiplatelet sticks and assembles, can prevent thrombosis, may contribute to prevent that angiemphraxis sexually transmitted disease (STD) from becoming PD, for preventing coronary artery and cerebral artery thrombosis thromboembolism.The most frequently used person is aspirin.3. thrombus dissolving and anticoagulant cause luminal stenosis or obstructor to intra-arterial formation thrombosis, and available thrombus preparation, uses anticoagulation 4. for the corresponding treatment of ischemia symptom then, applies vasodilation and beta-blocker etc. during as angina pectoris.(2) advantages such as Chinese medicine Chinese medicine primary disease has many targeting, integrally-regulated, and side effect is little, by balance the body yang blood and qi and function, Chinese medicine can delay course advancement and improve patient's symptom and sign.Different doctors have and stress for the pathogenesis viewpoint of primary disease, so but the basic pathogenesis of all approving primary disease in function loss, phlegm and blood stasis, simulataneous insufficiency and excessive.During treatment, according to state of an illness regulating functions of ZANG FU-organs, phlegm reduction of blood circulation promoting, can play good curative effect conventionally.Modern pharmacological research also shows, some have the merit of invigorating blood circulation and QI invigorating can medicines can play protection tunica intima, antiatherogenic effect, as Radix Salviae Miltiorrhizae, the Radix Astragali, Fructus Ligustri Lucidi, the Cortex Eucommiae etc.
Summary of the invention
The object of the present invention is to provide the Chinese medicine preparation with treatment atherosclerosis and coronary heart disease, to general performance, may occur that the symptoms such as mental and flag, atherosclerosis of aorta, coronary atherosclerosis have good preventive and therapeutic action.
The technical solution used in the present invention is: the Chinese medicine preparation of described treatment atherosclerosis and coronary heart disease, its primary raw material and weight portion respectively, 30 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiong, 18 parts of the Radix Paeoniae Albas, 30 parts, Fructus Hordei Germinatus, 12 parts, Flos Carthami, 12 parts of Thallus Laminariae (Thallus Eckloniae)s, 10 parts of Herba Menthaes, 30 parts of Folium Fumicis Dentatis, 30 parts of Rhizoma Phragmitiss.
The present invention selects Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Fructus Hordei Germinatus, Flos Carthami, Thallus Laminariae (Thallus Eckloniae), Herba Menthae, Folium Fumicis Dentati, Rhizoma Phragmitis to combine, by these drug regimens, thus make that each efficacy of drugs produces synergism strengthening medicine to functions such as flag, atherosclerosiss of aorta, can effectively treat atherosclerosis and coronary heart disease.
The selected raw material of the present invention, its property of medicine and effect respectively:
Radix Angelicae Sinensis: [chemical composition] contains basic lactone, n-butene acyl lactone, ferulic acid, nicotinic acid, sucrose and several amino acids, and sesquiterpenoids etc.[meridian distribution of property and flavor] is warm in nature, hides sweet, pungent.Return liver, the heart, spleen channel.[function cures mainly] enriched blood and invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.[function with cure mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for pacifying nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
The Radix Paeoniae Alba: (formal name used at school: Paeonia sterniana Fletcher in Journ.) also claiming Paeonia sterniana Fletcher in Journ., is Ranunculaceae Paeonia plant.Root is used as medicine.Root is containing paeoniflorin, paeonol, paeoniflorin, benzoic acid approximately 1.07%, volatile oil, fatty oil, resin, tannin, sugar, starch, phlegmatic temperament, protein, cupreol and triterpenes.Staphylococcus aureus is had to inhibitory action.The Radix Paeoniae Alba is cool in nature, and bitter in the mouth acid, is slightly cold, and has the easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing is received the effects such as antiperspirant, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction anxious, dysentery stomachache, spontaneous sweating, metrorrhagia, is with inferior disease.That paeoniflorin has is antibiotic, analgesic, antiinflammatory, increase coronary flow, improve the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjusting blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.Mainly antibiotic pain relieving, can depressed liver-energy dispersing and QI regulating, easing the affected liver nourishes blood, slow in pain relieving, suppressing the hyperactive liver yin fluid astringing, be usually used in distending pain in the chest and hypochondrium, epigastric pain due to incoordination between the liver and stomach, menoxenia, abdominal pain during menstruation, metrorrhagia, and spontaneous perspiration, night sweat, headache, the disease such as dizzy.
Fructus Hordei Germinatus: the mature fruit of grass Fructus Hordei Vulgaris Hordeum vulgare L. obtains through germinateing dry.Promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back newborn relieving distension.For food stagnation, do not disappear, abdominal distention, insufficiency of the spleen lack of appetite, newborn antiperspirant smoulders, distending pain of the breast, women's ablactation, Fructus Hordei Germinatus invigorating the spleen and regulating the stomach lactogenesis.For insufficiency of the spleen lack of appetite, newborn antiperspirant smoulders.The galactopoiesis of Fructus Hordei Germinatus (parched) promote qi circulation digestion promoting.For food stagnation, do not disappear, women's ablactation.Fructus Hordei Germinatus (parched to brown) relieving dyspepsia.For food stagnation, do not disappear, abdominal distention.Main warming the middle warmer and descending qi, appetite promoting and the spleen strengthening, expedites the emergence of lower tire, changes dyspepsia, and except distension, emesis is contrary, broken note of the ancient Chinese, expectorant painful abdominal mass.Digestion-aid effect: this product is containing α and beta amylase.And starch is the mixture of amylose and amylopectin.The glucose molecule that forms amylose is connected with α-Isosorbide-5-Nitrae glycoside key, and is straight chain arrangement.Amylopectin is by several short straight chain polyglucose cross arrangements.In amylopectin molecule, except α-Isosorbide-5-Nitrae glycoside key, also have α-1,6 glycoside keys.α and beta amylase hydrolyzable α-Isosorbide-5-Nitrae glycoside key, to α-1,6 glycoside keys are without effect.Beta amylase can become maltose by amylose complete hydrolysis, and alpha amylase makes it to resolve into short straight key polyglucose (being dextrin), and the latter can be again for beta amylase be hydrolyzed into maltose.Therefore starch can resolve into maltose and dextrin under the effect of α and beta amylase.Fructus Hordei Germinatus decoct seemingly has slight facilitation to gastric acid and pepsic secretion.
Flos Carthami: [chemical composition] is containing carthamin, neocarthamin, Flos Carthami quinone glycoside, Flos Carthami polysaccharide, Palmic acid, cinnamic acid, lauric acid.[nature and flavor] are warm in nature, acrid in the mouth.[function cures mainly] promoting blood circulation to restore menstrual flow, scattered silt pain relieving, for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Thallus Laminariae (Thallus Eckloniae): Thallus Laminariae (Thallus Eckloniae) is thallus or the Alariaceae plant of Laminariaceae plant Thallus Laminariae (Thallus Eckloniae) Laminaria japonica Arsch., dry rear pitchy.Chemical composition is containing algin element (algin), mannitol (mannitol), galactan (galactan), laminine (laminine), Thallus Laminariae (Thallus Eckloniae) polysaccharide (laminarin), glutamic acid, aspartic acid, proline, vitamin B1, C, P and iodine, potassium etc.[effect and effect]: eliminating phlegm and softening indurated mass; Diuretic detumescent.Main scrofula; Goiter; Dysphagic; (Epileptic is ruined) hernia beriberi edema.For goiter, scrofula, painful and swollen testis, phlegm retention edema.
Herba Menthae: popular name is " lunar caustic grass ", for labiate " Herba Menthae " belongs to other dry herbs together.The blue or green gas fragrance of Herb.Leaf, to life, is spent little lavender, and lip is spent the dark violet brown granule fruit of rear knot.Herba Menthae is one of Chinese conventional Chinese medicine.It is pungent cool property sweating antipyretic medicine, controls influenza, headache, conjunctival congestion, fever of the body, throat, the dental bed disease such as swell and ache.External can training the mind dysmenorrhoea, skin pruritus, erythra and eczema etc.The Herba Menthae of light friend Greenhouse Fruit Picking is again the fresh vegetable on dining table in the Spring Festival.Clearly good to eat.Usually with Herba Menthae for tea, improving eyesight clears away heart-fire.
Rhizoma Phragmitis: nature and flavor: sweet, cold.Gui Jing: return lung meridian, stomach warp.Function: clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.Cure mainly: for calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.Rhizome contains vitamin B1, B2, C and the protein 5% of volume, fat 1%, carbohydrate 51%, agedoite 0.1%.Contain again aminoacid, fatty acid, sterol, tocopherol, polyhydric phenols is as caffeic acid and gentisic acid.Also containing 2,5-dimethoxy-p-benzoquinone, p-hydroxybenzaldehyde, syringic aldehyde, coniferyl aldehyde, vanillic acid, ferulic acid, p-coumaric acid and dioxane lignin.The latter's oxidative breakdown product is the guaiaci lignum phenolic group of phenylpropyl alcohol alkane, the derivant of Flos Caryophylli phenolic group and 4-hydroxy phenyl.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.For example these crude drug pulverize mix homogeneously powder can be taken after mixing it with water; Can be by these crude drug together decocting, then concentrated decocting liquid is taken, or concentrated decocting liquid is condensed into cream is processed into pill and takes; In order to make each raw material of this medicine bring into play better drug effect, for certain crude drug, carry out special extraction, as ethanol extraction, these can not be for limiting the scope of the invention.Active component of the present invention can add various conventional adjuvant required while preparing different dosage form, as disintegrating agent, lubricant, binding agent etc. are prepared into any conventional peroral dosage form with conventional method of Chinese medicinal, as pill, powder, tablet, capsule, oral liquid etc.
Medicine of the present invention has promoting blood circulation to restore menstrual flow, and scattered silt pain relieving effect, is used for the treatment of atherosclerosis and coronary heart disease.So far, still do not find report and the application of relevant Chinese medicine preparation of the present invention.The inventor, through research repeatedly, and by the checking repeatedly of clinical trial, has finally found the endo-medicine that has better curative effect, thereby has completed the present invention.
The specific embodiment
The technical solution used in the present invention is: the Chinese medicine preparation of described treatment atherosclerosis and coronary heart disease, its primary raw material and weight portion respectively, 30 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiong, 18 parts of the Radix Paeoniae Albas, 30 parts, Fructus Hordei Germinatus, 12 parts, Flos Carthami, 12 parts of Thallus Laminariae (Thallus Eckloniae)s, 10 parts of Herba Menthaes, 30 parts of Folium Fumicis Dentatis, 30 parts of Rhizoma Phragmitiss.
Claims (1)
1. a Chinese medicine preparation for the treatment of atherosclerosis and coronary heart disease, it is characterized in that: its primary raw material and weight portion respectively, 30 parts of Radix Angelicae Sinensis, 15 parts of Rhizoma Chuanxiong, 18 parts of the Radix Paeoniae Albas, 30 parts, Fructus Hordei Germinatus, 12 parts, Flos Carthami, 12 parts of Thallus Laminariae (Thallus Eckloniae)s, 10 parts of Herba Menthaes, 30 parts of Folium Fumicis Dentatis, 30 parts of Rhizoma Phragmitiss.
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| CN201310524895.4A CN103550624A (en) | 2013-10-23 | 2013-10-23 | Traditional Chinese medicine preparation for treating atherosclerosis and coronary heart disease |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104922504A (en) * | 2015-05-29 | 2015-09-23 | 张慧玲 | Vinegar beverage for treating atherosclerosis and preparation method thereof |
| CN109007468A (en) * | 2017-11-03 | 2018-12-18 | 阿卜杜米吉提·阿卜力孜 | The HD Wu Zuer functional beverage of assisting in treating hypertension and hyperlipidemia |
-
2013
- 2013-10-23 CN CN201310524895.4A patent/CN103550624A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104922504A (en) * | 2015-05-29 | 2015-09-23 | 张慧玲 | Vinegar beverage for treating atherosclerosis and preparation method thereof |
| CN109007468A (en) * | 2017-11-03 | 2018-12-18 | 阿卜杜米吉提·阿卜力孜 | The HD Wu Zuer functional beverage of assisting in treating hypertension and hyperlipidemia |
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Application publication date: 20140205 |