CN103550348A

CN103550348A - Traditional Chinese medicine formula for treating chronic erosive gastritis

Info

Publication number: CN103550348A
Application number: CN201310542578.5A
Authority: CN
Inventors: 咸温东
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-11-06
Filing date: 2013-11-06
Publication date: 2014-02-05
Anticipated expiration: 2033-11-06
Also published as: CN103550348B

Abstract

The invention belongs to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine formula for treating chronic erosive gastritis, which is prepared from the following active pharmaceutical ingredients in parts by weight: 30-40 parts of radix astragali, 8-15 parts of Bighead Atractylodes Rhizome, 10-20 parts of tuckahoe, 8-15 parts of radix bupleuri, 10-20 parts of dried orange peel, 8-15 parts of costus root, 8-15 parts of corydalis tuber, 8-15 parts of gardenia, 25-35 parts of taraxacum, 10-25 parts of radix salviae miltiorrhizae, 8-15 parts of red paeonia and 5-10 parts of licorice. The formula has the advantages of reasonable prescription and obvious curative effect.

Description

A kind of Chinese medicinal formulae for the treatment of chronic erosive gastritis

Technical field

The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicinal formulae for the treatment of chronic erosive gastritis.

Background technology

Chronic erosive gastritis, claims again the indigestion symptoms such as general rarely seen glutted, the pantothenic acid after meal of gastritis verrucosa or varioliform gastritis, belch, irregularities stomachache.The cause of disease that causes primary disease can be the reasons such as some drugs, food, microbiological factor, bacteriotoxin, if treatment not in time, the harm that primary disease can cause is to form ulcer, cause gastric perforation, because erosive gastritis is HP(helicobacter pylori) amount reproduction provides good interior environment, stimulate HP to secrete more many cells toxin, also have carcinogenic probability.The current medicine of western medical treatment primary disease is clinically roughly protection gastric mucosa and eliminates the medicine of infringement gastric mucosa, generally have apparent side effect, and curative effect is single, and effective percentage is low, rear easily recurrence.On tcm clinical practice, take the Therapeutic Method of determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, but current medicine obviously exists the course for the treatment of long more, take effect slow, DeGrain and take the shortcomings such as inconvenient.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicinal formulae for the treatment of chronic erosive gastritis, this prescription can reach the effect of chronic erosive gastritis treating both the principal and secondary aspects of a disease.

The present invention is made by the crude drug of following weight proportion:

Radix Astragali 30-40 part, Rhizoma Atractylodis Macrocephalae 8-15 part, Poria 10-20 part, Radix Bupleuri 8-15 part, Pericarpium Citri Reticulatae 10-20 part, Radix Aucklandiae 8-15 part, Rhizoma Corydalis 8-15 part, Fructus Gardeniae 8-15 part, Herba Taraxaci 25-35 part, Radix Salviae Miltiorrhizae 10-25 part, Radix Paeoniae Rubra 8-15 part, Radix Glycyrrhizae 5-10 part.

Its preferred each crude drug weight ratio is: 30 parts of the Radixs Astragali, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts, Poria, 10 parts of Radix Bupleuri, 12 parts of Pericarpium Citri Reticulataes, 10 parts of the Radix Aucklandiae, 10 parts of Rhizoma Corydalis, 10 parts of Fructus Gardeniaes, 30 parts of Herba Taraxacis, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Paeoniae Rubra, 6 parts, Radix Glycyrrhizae.

Instructions of taking of the present invention is: every dose of medicine is decocted juice 300ml, every 150ml that takes, every day 2 times, sub-service sooner or later.

In the present invention, the pharmacological action of each crude drug is as follows:

The Radix Astragali: sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; For chronic nephritis proteinuria, diabetes.

The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.

Poria: sweet, light, flat.GUIXIN, spleen, kidney channel.Promoting diuresis to eliminate damp pathogen, spleen invigorating, calms the nerves.Cure mainly edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.

Radix Bupleuri: hardship, is slightly cold.Return liver, gallbladder meridian.Reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.

Pericarpium Citri Reticulatae: arduous, temperature.Return spleen, lung meridian.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Cure mainly fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.

The Radix Aucklandiae: warm in nature, acrid in the mouth, hardship.Promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.For heavy after breast gastral cavity distending pain, dysentery, food stagnation does not disappear, anorexia.

Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.

Fructus Gardeniae: hardship, cold.GUIXIN, lung, tri-jiao channel.Pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood is told nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.

Herba Taraxaci: bitter, sweet, cold.Return liver, stomach warp.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.

Radix Salviae Miltiorrhizae: hardship, is slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, { note of the ancient Chinese } abdominal mass is gathered, breast ventral spine pain, and pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.

Radix Paeoniae Rubra: hardship, is slightly cold.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea.

Radix Glycyrrhizae: sweet, flat.GUIXIN, lung, spleen, stomach warp.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

Technical problem to be solved by this invention be to provide a kind of quicker than existing curative effect of medication, cure rate is high, be difficult for the Chinese medicinal formulae of the treatment chronic erosive gastritis of recurrence.The Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria invigorating the spleen and benefiting QI in prescription of the present invention; Radix Bupleuri, Pericarpium Citri Reticulatae, the Radix Aucklandiae, Rhizoma Corydalis, Fructus Gardeniae, Herba Taraxaci, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra promoting flow of QI and blood, heat clearing and inflammation relieving pain relieving; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, relieving spasm to stop pain; All medicines share, and play altogether spleen invigorating and regulate the flow of vital energy, the merit of dissipating blood stasis and clearing away heat.Medicine card conforms to, therefore the satisfaction of producing effects.

clinical verification

1. MethodsThe cases enrolled:

The present invention verifies chronic erosive gastritis patient 124 examples, and all patients all meet chronic erosive gastritis diagnostic criteria.After diagnosis is clear and definite, be divided into two groups, treatment group 64 examples, male patient's 34 examples, female patient's 30 examples, age 35-63 year, course of disease 2-4 is not etc.; Matched group 60 examples, male patient's 31 examples, female patient's 29 examples, in age 35-65 year, course of disease 2-4 is not etc.

2. efficacy determination: adopt 4 grade standards.

Cure: chronic erosive gastritis symptom all disappears.

Effective: chronic erosive gastritis symptom obviously alleviates.

Effective: chronic erosive gastritis symptom makes moderate progress.

Invalid: chronic erosive gastritis symptom has no to disappear.

3. clinical effectiveness:

Treatment group: totally 64 examples, cure 57 examples, account for 89.0%; Effective 6 examples, account for 9.4%; Invalid 1 example, accounts for 1.6%; Total effective rate is 98.4%.

Matched group: totally 60 examples, cure 43 examples, account for 71.7%; Effective 4 examples, account for 6.7%; Invalid 13 examples, account for 21.6%; Total effective rate is 78.4%.

Result shows, treatment group and matched group comparison, and difference significance, illustrates that the therapeutic effect for the treatment of group is obviously better than matched group.

The present invention writes out a prescription rationally, evident in efficacy, has no side effect, safe.

The specific embodiment

Below in conjunction with embodiment, the invention will be further described.

embodiment 1:

Take by weight following crude drugs, 30 parts of the Radixs Astragali, 8 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts, Poria, 8 parts of Radix Bupleuri, 10 parts of Pericarpium Citri Reticulataes, 8 parts of the Radix Aucklandiae, 8 parts of Rhizoma Corydalis, 8 parts of Fructus Gardeniaes, 25 parts of Herba Taraxacis, 10 parts of Radix Salviae Miltiorrhizaes, 8 parts of Radix Paeoniae Rubra, 5 parts, Radix Glycyrrhizae.

Above-mentioned 12 taste Chinese herbal medicine are added water to 500mL and soak one hour, intense fire boils, and slow fire decocted to 3 hours, the filtrate 300mL left and right of removing slag to obtain, and instructions of taking is that every dose of medicine is decocted juice 300ml, every 150ml that takes, every day 2 times, sub-service sooner or later.

embodiment 2:

Take by weight following crude drugs, 30 parts of the Radixs Astragali, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts, Poria, 10 parts of Radix Bupleuri, 12 parts of Pericarpium Citri Reticulataes, 10 parts of the Radix Aucklandiae, 10 parts of Rhizoma Corydalis, 10 parts of Fructus Gardeniaes, 30 parts of Herba Taraxacis, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Paeoniae Rubra, 6 parts, Radix Glycyrrhizae.

embodiment 3:

Take by weight following crude drugs, 40 parts of the Radixs Astragali, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts, Poria, 15 parts of Radix Bupleuri, 20 parts of Pericarpium Citri Reticulataes, 15 parts of the Radix Aucklandiae, 15 parts of Rhizoma Corydalis, 15 parts of Fructus Gardeniaes, 35 parts of Herba Taraxacis, 25 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Paeoniae Rubra, 10 parts, Radix Glycyrrhizae.

Claims

1. treat a Chinese medicinal formulae for chronic erosive gastritis, it is characterized in that being made by the crude drug of following weight proportion: Radix Astragali 30-40 part, Rhizoma Atractylodis Macrocephalae 8-15 part, Poria 10-20 part, Radix Bupleuri 8-15 part, Pericarpium Citri Reticulatae 10-20 part, Radix Aucklandiae 8-15 part, Rhizoma Corydalis 8-15 part, Fructus Gardeniae 8-15 part, Herba Taraxaci 25-35 part, Radix Salviae Miltiorrhizae 10-25 part, Radix Paeoniae Rubra 8-15 part, Radix Glycyrrhizae 5-10 part.

2. Chinese medicinal formulae according to claim 1, is characterized in that being made by following raw material medicaments: 30 parts of the Radixs Astragali, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts, Poria, 10 parts of Radix Bupleuri, 12 parts of Pericarpium Citri Reticulataes, 10 parts of the Radix Aucklandiae, 10 parts of Rhizoma Corydalis, 10 parts of Fructus Gardeniaes, 30 parts of Herba Taraxacis, 20 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Paeoniae Rubra, 6 parts, Radix Glycyrrhizae.