CN103505324B - Intelligent medical adhesive tape - Google Patents

Intelligent medical adhesive tape Download PDF

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Publication number
CN103505324B
CN103505324B CN201210211680.2A CN201210211680A CN103505324B CN 103505324 B CN103505324 B CN 103505324B CN 201210211680 A CN201210211680 A CN 201210211680A CN 103505324 B CN103505324 B CN 103505324B
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China
Prior art keywords
adhesive tape
intelligent medical
medical adhesive
release
tape according
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Application number
CN201210211680.2A
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Chinese (zh)
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CN103505324A (en
Inventor
胡军
赵晓芳
赵静
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Jianerkang Medical Technology Co ltd
Jiangsu jianerkang Medical Technology Co.,Ltd.
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Individual
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Priority to CN201210211680.2A priority Critical patent/CN103505324B/en
Publication of CN103505324A publication Critical patent/CN103505324A/en
Application granted granted Critical
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/023Adhesive plasters or dressings wound covering film layers without a fluid handling layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive plasters or dressings
    • A61F13/0276Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F13/0289Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of adhesive dressings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Manufacturing & Machinery (AREA)
  • Adhesive Tapes (AREA)
  • Medicinal Preparation (AREA)
  • Adhesives Or Adhesive Processes (AREA)

Abstract

The invention discloses time response type intelligent medical adhesive tape and a manufacturing method thereof. The intelligent medical adhesive tape comprises mounting materials, a slow-release layer, a medical pressure sensitive adhesive layer and product release paper. The time response type intelligent medical adhesive tape is characterized in that the slow-release layer can release the lubricating agent regularly, the adhesive tape can lose viscidity in the set time and fall off automatically, and regular fixation is achieved. The intelligent medical adhesive tape has the advantages of being non-poisonous, free from extraneous odour, free of stimulation, light, thin, soft, good in breathability and the like, and has broad market prospects.

Description

A kind of Intelligent medical adhesive tape
Technical field
The present invention relates to a kind of medical adhesive tape, particularly relate to a kind of Intelligent medical adhesive tape at energy self falling of specific time (as 24h).
Background technology
Polyvinyl alcohol (Polyvinyl alcohol is called for short PVA) is the water-soluble polymer obtained through alkali catalyzed alcoholysis by polyvinyl acetate.A kind of purposes of PVA is quite extensive, in spinning sizing agent, coating, adhesive, emulsifying agent, paper conversion auxiliary agent, thin film, packaging for foodstuff, building materials, medicine etc., have application.In recent years, along with polymer material science and medicine and pharmacology development and interpenetrate, greatly facilitate macromolecular material and combine with medical, the purposes of PVA in slow-releasing system becomes the popular direction of research.PVA has excellent film property, and safety non-toxic, good biocompatibility.In medicine film, PVA is mainly used as the filmogen of membrane, as the permanent carrier of medicine, and make various medicaments uniformity be dispersed in wherein, in certain release environment, along with the interaction of hydrophilic PVA and water, form the gel layer of thickness on membrane surface and progressively dissolve, the medicine of the inside is spread lentamente by gel layer, discharges, thus optimization drug release rate, improve drug effect and reduce toxic and side effects.The water solublity of PVA depends primarily on degree of hydrolysis and average degree of polymerization, therefore also by regulating the rate of dissolution of these two kinds of controlling factors PVA, and then reaches the object of regulating drug rate of release.If add inorganic nano material in the material and obtained composite, this will significantly improve raw-material rigidity, toughness, intensity, heat stability, wearability etc.
Along with the development of traditional Chinese medicine technology, plaster is more and more applied to cures some commonly encountered diseases aspects, as rheumatic arthritis, hyperosteogeny, lumbago and skelalgia etc.Plaster because it is easy to use, curative effect is fast, need not operate on, need not take medicine, do not affect the advantages such as routine work life and be widely used.But after a lot of people sticks plaster, be easy to sometimes forget, and after somebody sticks, just do not know when this peels, the even subsides couple of days had.In fact, the efficacy of a drug of plaster has certain timeliness, and cream the effective elements of the medicine has absorbed and has been over by skin, if time delay is not torn, will increase the weight of the burden of skin, hinder the penetrating of pore, blocks perspiration and discharges, even there will be atopic dermatitis etc.If invention is a kind of with " memory chip " medical adhesive tape, when bringing into use, " timer " starts timing, arrives the regular hour, medical adhesive tape self falling, and just can solve plaster can not the problem of timed drug administrations.Therefore PVA material is implanted medical adhesive tape by us, by reaching the object controlling the adhesive tape sticking time to the slow release of water.
Summary of the invention
The technical problem to be solved in the present invention, modest viscosity when being to provide a kind of use, fixing reliable, in the Intelligent medical adhesive tape of specific time Automatic-falling.
The present invention adopts following technical scheme:
In order to achieve the above object, the medical adhesive tape at specific time Automatic-falling involved in the present invention, is characterized in that being made up of mount material 1, first medical pressure-sensing glue-line 2, slow release layer 3, second medical pressure-sensing glue-line 4 and product release paper 5.
Described material of mounting is selected from non-woven fabrics or mulberry paper, and material of preferably mounting is non-woven fabrics.
Described slow release layer 3 is made up of the first release paper 6, water-bearing layer 7, second release paper 8 and release membranes 9, wherein the first release paper 6 and the second release paper 8 are PE tectorial paper or silicone oil paper, thickness is between 0.01 millimeter to 0.1 millimeter, preferred release paper is silicone oil paper, and preferred thickness is 0.02 millimeter to 0.05 millimeter.
Described water-bearing layer 7 is made up of non-woven fabrics and deionized water, and the moisture content of non-woven fabrics is 10% ~ 80%, and preferred non-woven fabrics moisture content is 20% ~ 50%.
Described release membranes 9 is selected from the one in polyvinyl alcohol or polyvinyl alcohol/inorganic nanometer particle composite material, preferred release membranes material is polyvinyl alcohol/inorganic nanometer particle composite material, and described polyvinyl alcohol/inorganic nanometer composite is prepared through sol-gel process by vinylacetate (A), inorganic nano-particle (B) and partial solvent (C).It consists of mark meter by weight, and vinylacetate (1 ~ 90 part), inorganic nano-particle (1 ~ 90 part) and solvent (1 ~ 10 part), preferred vinyl acetate content is 30 ~ 70 parts, and inorganic nano-particle can be selected from SiO 2, TiO 2, WO 3, CdS, Ag 2one or more in S, preferred inorganic nano-particle is nanosized SiO_2, preferred content is 30 ~ 60 parts, and solvent can be selected from one or more in methanol, acetone, toluene, and preferred solvent is methanol, preferred content is 4 ~ 8 parts, the molecular weight of composite is 500 ~ 20, and between 000, preferred composite molecular weight is 1,000 ~ 1, between 0000.
Aforesaid time response type Intelligent medical adhesive tape production method, its production stage is as follows:
A, material 1 of mounting carry out sided corona treatment,
B, application coating process are coated with medical pressure-sensitive adhesive 2 in the one side of material 1 through sided corona treatment of mounting,
C, polyvinyl alcohol/inorganic nanometer composite is coated in the middle of two-layer release paper, obtained slow release layer 3, and cutting forming,
D, by the slow release layer 3 of good for cross cutting shape and the Material cladding of mounting scribbling medical pressure-sensitive adhesive,
E, be coated with medical pressure-sensitive adhesive 4 on slow release layer 3 surface, and enclose product release paper 5,
F, finishing die are cut into net shape.
Wherein the production stage of slow release layer 3 is as follows, and first sealed in water-bearing layer 7 with the first release paper 6 and the second release paper 88, polyvinyl alcohol or polyvinyl alcohol/inorganic nanometer composite are prepared into release membranes.
When using Intelligent medical adhesive tape, the second release paper 8 is extracted out, and product release paper 5 is opened, be affixed on the position of needs.
Beneficial effect: time response of the present invention type Intelligent medical adhesive tape, by slow release layer, slow release is carried out to the deionized water in water-bearing layer, the medical pressure-sensitive adhesive contacting skin after the regular hour loses viscosity Automatic-falling because of the effect of water, reach and control the object that medical adhesive tape pastes the time.
Accompanying drawing explanation
Fig. 1 is the front view of type Intelligent medical adhesive tape time response.
Fig. 2 is the top view of type Intelligent medical adhesive tape time response.
Fig. 3 is the front view of slow release layer (3).
Wherein 1, material 2, first medical pressure-sensing glue-line 3 of mounting, slow release layer 4, second medical pressure-sensing glue-line 5, product release paper 6, first release paper 7, water-bearing layer 8, second release paper 9, release membranes
Detailed description of the invention
Below in conjunction with drawings and Examples, the invention will be further described.Following content is in conjunction with concrete preferred implementation further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For person skilled in the art of the present invention, without departing from the inventive concept of the premise, its framework form can be flexible and changeable, can derive series of products.Just make some simple deduction or replace, all should be considered as belonging to the scope of patent protection that claims that the present invention submits to are determined.
Embodiment 1: one type Intelligent medical adhesive tape time response, as shown in Figure 1, it is made up of mount material 1, first medical pressure-sensing glue-line 2, slow release layer 3 second medical pressure-sensing glue-line 4 and product release paper 5.
As shown in Figure 3, in this embodiment, slow release layer 3 is made up of the first release paper 6, water-bearing layer 7, second release paper 8 and release membranes 9.Water-bearing layer 7 is wrapped in wherein by the first release paper 6 and the second release paper 8, and the first release paper 6 and the second release paper 8 are silicone oil paper, and thickness is 0.02 millimeter, and the length of the second release paper 8 extension is 1 centimetre, so that extract out; The non-woven fabrics that water-bearing layer 7 is 80% by moisture content forms; The polyvinyl alcohol/inorganic nanometer composite (molecular weight is 2000) selected in release membranes 9 is by (by mass fraction) vinylacetate 60 parts, SiO 280 parts, methanol 10 parts, through sol-gel process preparation, uses casting method to be coated in by polyvinyl alcohol/inorganic nanometer composite on the second release paper 8, obtained slow release layer 3, and cutting forming.
Non-woven fabrics selected by described material 1 of mounting, and first carries out sided corona treatment to it, then applies coating process and is coated with medical pressure-sensitive adhesive 2 at non-woven fabrics through the one side of sided corona treatment; By the slow release layer 3 of good for cross cutting shape and the Material cladding of mounting scribbling medical pressure-sensitive adhesive, be coated with medical pressure-sensitive adhesive 4 on slow release layer 3 surface, and enclose product release paper 5, finishing die is cut into net shape.
Wherein the production stage of slow release layer 3 is as follows, and first sealed in water-bearing layer 7 with the first release paper 6 and the second release paper 8, polyvinyl alcohol or polyvinyl alcohol/inorganic nanometer composite are prepared into release membranes.
When using Intelligent medical adhesive tape, the second release paper 8 is extracted out, and product release paper 5 is opened, be affixed on the position of needs.

Claims (11)

1. time response a type Intelligent medical adhesive tape, it is characterized in that: described Intelligent medical adhesive tape is made up of material of mounting (1), the first medical pressure-sensing glue-line (2), slow release layer (3), the second medical pressure-sensing glue-line (4) and product release paper (5); Described slow release layer (3) is made up of the first release paper (6), water-bearing layer (7), the second release paper (8) and release membranes (9).
2. Intelligent medical adhesive tape according to claim 1, is characterized in that: described material of mounting (1) is non-woven fabrics, any one in mulberry paper.
3. Intelligent medical adhesive tape according to claim 2, is characterized in that: described the first release paper (6) and the second release paper (8) are PE tectorial paper or silicone oil paper, and thickness is between 0.01 millimeter to 0.1 millimeter.
4. Intelligent medical adhesive tape according to claim 2, is characterized in that: described water-bearing layer (7) is that 10% ~ 80% non-woven fabrics and deionized water form by moisture content.
5. Intelligent medical adhesive tape according to claim 2, is characterized in that: described release membranes (9) is formed by polyvinyl alcohol or polyvinyl alcohol/inorganic nanometer composite processing.
6. Intelligent medical adhesive tape according to claim 5, is characterized in that: described polyvinyl alcohol/inorganic nanometer composite is prepared through sol-gel process by vinylacetate (A), inorganic nano-particle (B) and partial solvent (C).
7. Intelligent medical adhesive tape according to claim 6, is characterized in that: described polyvinyl alcohol/inorganic nanometer composite, and in mass fraction, its composition comprises:
(A) vinylacetate 1 ~ 90 part
(B) inorganic nano-particle 1 ~ 90 part
(C) solvent 1 ~ 10 part.
8. Intelligent medical adhesive tape according to claim 6, is characterized in that: described inorganic nano-particle (B) is selected from Nano-meter SiO_2 2, TiO 2, WO 3, CdS, Ag 2one or more in S.
9. Intelligent medical adhesive tape according to claim 6, is characterized in that: described solvent (C) is selected from one or more in methanol, acetone, toluene.
10. a production method for Intelligent medical adhesive tape as claimed in claim 1, is characterized in that: production stage is as follows:
A, application coating process are coated with medical pressure-sensitive adhesive (2) in the one side of material of mounting (1),
B, interpolation slow release layer (3),
C, enclose product release paper (5) at the upper medical pressure-sensitive adhesive (4) of slow release layer (3),
D, finishing die are cut into final shape.
The production method of 11. Intelligent medical adhesive tape according to claim 10, is characterized in that: the production stage of slow release layer (3) is as follows:
A, with release paper, the non-woven fabrics containing deionized water to be sealed,
B, with casting method, polyvinyl alcohol or polyvinyl alcohol/inorganic nanometer composite are prepared into release membranes.
CN201210211680.2A 2012-06-26 2012-06-26 Intelligent medical adhesive tape Active CN103505324B (en)

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Application Number Priority Date Filing Date Title
CN201210211680.2A CN103505324B (en) 2012-06-26 2012-06-26 Intelligent medical adhesive tape

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CN103505324A CN103505324A (en) 2014-01-15
CN103505324B true CN103505324B (en) 2015-07-08

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013371583B2 (en) * 2013-01-02 2018-02-01 3M Innovative Properties Company A flexible, adherent, and non-polyurethane film wound drape cover
CN112691230A (en) * 2020-12-23 2021-04-23 上海弘生医疗科技有限公司 Silica gel dressing adhesive tape and preparation process thereof
CN113425502A (en) * 2021-06-22 2021-09-24 王春秋 Multifunctional vaccine application
CN113577367A (en) * 2021-08-13 2021-11-02 东莞市金保利卫生用品有限公司 Sanitary towel for recuperating and detoxifying and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2315934Y (en) * 1998-02-05 1999-04-28 喇万英 Medical relief air peameable adhesive plaster
CN101147744A (en) * 2006-09-21 2008-03-26 郭威岩 Chitin water soluble aerosol and wound applied block composite medicine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110218472A1 (en) * 2010-03-02 2011-09-08 Iran Polymer And Petrochemical Institute (Ippi) Non drug based wound dressing polymer film and a method of producing the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2315934Y (en) * 1998-02-05 1999-04-28 喇万英 Medical relief air peameable adhesive plaster
CN101147744A (en) * 2006-09-21 2008-03-26 郭威岩 Chitin water soluble aerosol and wound applied block composite medicine

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Effective date of registration: 20200717

Address after: 213200 Jiangsu city of Changzhou province Jintan District Town Industrial Zone jianerkang Road No. 1

Patentee after: JIANGSU PROVINCE JIANERKANG MADICAL DRESSING CO.,LTD.

Address before: 215000, Jiangsu Suzhou Industrial Park, sun star garden, phase 9, 1901

Patentee before: Zhao Jing

TR01 Transfer of patent right
CP01 Change in the name or title of a patent holder

Address after: No.1 jianerkang Road, Zhixi Town, Jintan District, Changzhou City, Jiangsu Province

Patentee after: Jianerkang Medical Technology Co.,Ltd.

Address before: No.1 jianerkang Road, Zhixi Town, Jintan District, Changzhou City, Jiangsu Province

Patentee before: Jiangsu jianerkang Medical Technology Co.,Ltd.

Address after: No.1 jianerkang Road, Zhixi Town, Jintan District, Changzhou City, Jiangsu Province

Patentee after: Jiangsu jianerkang Medical Technology Co.,Ltd.

Address before: No.1 jianerkang Road, Zhixi Town, Jintan District, Changzhou City, Jiangsu Province

Patentee before: JIANGSU PROVINCE JIANERKANG MADICAL DRESSING CO.,LTD.

CP01 Change in the name or title of a patent holder