CN103503909A - Insecticidal composition containing 1-((6-chloropyridine-3-yl) methyl)-5-propoxy-7-methyl-8-nitryl-1,2,3,5,6,7-hexahydroimidazo[1,2-alpha] pyridine) and cypermethrin - Google Patents

Abstract

The invention relates to an insecticidal composition containing 1-((6-chloropyridine-3-yl) methyl)-5-propoxy-7-methyl-8-nitryl-1,2,3,5,6,7-hexahydroimidazo[1,2-alpha] pyridine) and cypermethrin, and the insecticidal composition is highly effective for preventing animal pests. The insecticidal composition comprises the active ingredients the 1-((6-chloropyridine-3-yl) methyl)-5-propoxy-7-methyl-8-nitryl-1,2,3,5,6,7-hexahydroimidazo[1,2-alpha] pyridine) and the cypermethrin, wherein the weight ratio of the 1-((6-chloropyridine-3-yl) methyl)-5-propoxy-7-methyl-8-nitryl-1,2,3,5,6,7-hexahydroimidazo[1,2-alpha] pyridine) to the cypermethrin is (1:25)-(25:1), and the percentage composition of the 1-((6-chloropyridine-3-yl) methyl)-5-propoxy-7-methyl-8-nitryl-1,2,3,5,6,7-hexahydroimidazo[1,2-alpha] pyridine) and the cypermethrin in total is 1%-80%. According to the invention, the binary combination is performed on the 1-((6-chloropyridine-3-yl) methyl)-5-propoxy-7-methyl-8-nitryl-1,2,3,5,6,7-hexahydroimidazo[1,2-alpha] pyridine) and the cypermethrin so as to achieve a synergic effect on the insecticidal efficacy, the control effects on preventing lepidoptera, homoptera and arachnoidea pests on wheat, rice and vegetables are remarkable, and particularly, the insecticidal composition has remarkable effects on preventing froghoppers, leafhoppers, treehoppers, fulgoras, plant hoppers, phylloxeras, whiteflies, aphids, scale insects, cotton bollworms, leaf mites, thrips and stinkbugs.

Description

A kind of Pesticidal combination containing paichongding and cypermethrin

Technical field

The present invention relates to a kind of Pesticidal combination containing paichongding and cypermethrin, described Pesticidal combination is effective to preventing and treating animal pest height.

Background technology

Chemical prevention is agriculturally or public health prevents and controls an important means for insect.However, currently used medicament is still not enough satisfied with to the effect of some insects；Also, because long-time uses insecticide, many insects have generated the resistance to common insecticide.Many suckings pest are the main causes of polytype cereal and the worldwide pest and disease damage in vegetables production, such as wherein representational insect comes from Heteroptera and Homoptera, particularly Delphacidae (Delphacidae) insect, frequent species has brown paddy plant hopper（Nilaparvata lugens）, white backed planthopper (Sogatella furcifera), small brown rice planthopper (Laodelphax striatellus, planthopper（Rice planthopper).Preventing and treating these insects has greatly economic worth.And carry out prevention and control using conventional dose and just becoming increasingly difficult.Therefore, in the urgent need to be developed for control these insects new method and medicine.In addition, also being improved constantly currently for requirement of the insecticide on environment and economic aspect, such as action spectrum, toxicity, selectivity, rate of application, residues of pesticides and favourable preparation ability.In addition, also as the problem of resistance may be produced for known activity compound, exploitation it is new at least at some or some aspects relative to the advantageous newtype drug of existing medicine just into a permanent task.

Paichongding, its chemical name is：1- ((6- chloropyridine -3- bases）Methyl）- 5- propoxyl group -7- methyl -8- nitros -1,2,3,5,6,7- hexahydro imidazo [1,2-a] pyridines, its structural formula is：

Paichongding belongs to new and effective, wide spectrum, the nicotinic insecticide of low toxicity, and the mechanism of action is the axle synaptic receptor for acting on insect nerve, block nerves conduction；Acting on has obvious Antifeedant Effects after gi system, pests；The lancet of sucking pest is acted on, it is not taken food.Paichongding is mainly used in preventing and treating homoptera pest, there is good prevention effect to insects such as planthoppers.Although paichongding has the new mechanism of action, but because it belongs to new nicotinic insecticide, there are still the risk that resistance is produced for long-term single use.

Cypermethrin, its structural formula is：

Its chemical formula is 2,2- dimethyl -3- (2,2- dichloroethylene) cyclopropane-carboxylic acid-alpha-cyano-(3- phenoxy groups) benzyl ester, cypermethrin, also known as Mie Baike, Xing Mianbao, An Lvbao, Sai Bokai, Fendona, is conventional insecticide.Cypermethrin is often presented with yellow to amber thick liquid, although difficulty is dissolved in water, but can be dissolved in organic solvent, such as alcohols, chlorinated hydrocarbon, ketone, hexamethylene, benzene, dimethylbenzene etc..Although it is easily decomposed on soil and plant, a kind of quick-acting neurotoxins.It, which has, tags and stomach poison function, photo-thermal is all stablized, drug effect is higher than Permethrin, it is adaptable to defending insect and killing, the insect such as flies, mosquito class and Simulium.

At present, it is not related to the report by paichongding and cypermethrin combination application also.

The content of the invention

The present invention seeks to solve at least one above-mentioned problem or its at least one aspect, control insect especially for effective, screened through a large amount of biological tests, inventors have surprisingly discovered that paichongding can be combined with cypermethrin for effectively preventing or controlling insect.The effect of this combination is especially good.

Therefore, contain paichongding and cypermethrin insecticide composition and application thereof it is an object of the present invention to provide one kind, be a kind of Pesticidal combination for including paichongding and cypermethrin as active component.

A kind of Pesticidal combination containing paichongding and cypermethrin of the present invention is to take following technical scheme to realize：

One kind contains paichongding and cypermethrin insecticide composition, it is characterised in that containing active component paichongding and cypermethrin, the wherein weight ratio of paichongding and cypermethrin is 1:25-25:1.

One kind contains paichongding and cypermethrin insecticide composition, it is characterised in that containing active component paichongding and cypermethrin, the wherein weight ratio of paichongding and cypermethrin is 1:10-10:1, preferably 1:5-5:1. 

One kind contains paichongding and cypermethrin insecticide composition, and the weight percentage that wherein paichongding accounts for composition altogether with cypermethrin is 1%-80%, more preferably preferably 5%-60%, 10%-50%.

Described one kind contains paichongding and cypermethrin insecticide composition, also comprising carrier, surfactant or other annexing ingredients.

Described one kind contains paichongding and cypermethrin insecticide composition, and formulation is：Suspending agent, microcapsules, missible oil, suspending agent, water dispersible granules, wettable powder, suspension emulsion, aqueous emulsion, suspension seed-coating agent, granule, dashing agent, drops, microemulsion, microcapsule suspension-suspendinagent agent.

Described one kind contains paichongding and cypermethrin insecticide composition, wherein the composition also includes one or more other active components.

A kind of described paichongding and the Pesticidal combination of cypermethrin are used for the purposes for preventing or controlling animal pest.

In another aspect, paichongding and cypermethrin insecticide composition, the purposes for preventing or controlling insect are contained present invention also offers described one kind.The Pesticidal combination of the present invention is applied to the animal pest that preventing and treating is found in terms of agricultural, animal health, forest, garden and Relexing device, the protection of Stored Product and health.

A kind of method for preventing or controlling animal pest, it is characterised in that one kind is acted on into animal pest and/or its environment containing paichongding and cypermethrin insecticide composition.

A kind of described method for preventing or controlling animal pest, it is characterised in that：By a kind of animal pest for acting on and being prevented and treated in terms of agricultural, animal health, forest, garden and Relexing device, the protection of Stored Product and health containing paichongding and cypermethrin insecticide composition.

It is a further object to provide a kind of kit for being used to preventing or controlling insect, it includes paichongding and cypermethrin.

It is of the invention a kind of containing paichongding and cypermethrin insecticide composition and application thereof; it is a kind of Pesticidal combination for including paichongding and cypermethrin as active component; by paichongding and cypermethrin compounded; with synergistic function, it is adaptable to the animal pest that preventing and treating is found in terms of agricultural, animal health, forest, garden and Relexing device, the protection of Stored Product and health.

Embodiment

Preferably to describe the present invention, there is provided following exemplary embodiment.

The present inventor unexpected has found：Paichongding is combined with cypermethrin can not only bring the additive property raising for insecticidal spectrum, and importantly, can realize amazing synergy.

Term " synergy " used herein refers to activating agent combination of the present invention or the insecticidal effect of composition is more than each activating agent effect sum, and in other words, its effect is superadditivity.In addition, referring also to " Isoboles, a graphic representation of synergism in pesticides ", Netherlands Journal of the Plant Pathology of effect defined in Tammes methods, 70 (1964), pages 73-80.

The invention provides a kind of Pesticidal combination for including paichongding and cypermethrin as active component.

The invention provides a kind of Pesticidal combination for including paichongding and cypermethrin as active component, the wherein weight ratio of paichongding and cypermethrin is 1:25 to 25:1, preferably 1:10 to 10:1, more preferably 1:5 to 5:1.

The total amount of active compound component can be selected according to material elements in Pesticidal combination of the present invention, and to realize desired effect, the factor is such as formulation, object to be administered, application process.In one embodiment, paichongding and cypermethrin account for the composition 1%-80% by weight, more preferably preferably 5%-60%, 10%-50% altogether.

The Pesticidal combination of the present invention optionally includes agronomically acceptable carrier, surfactant or other annexing ingredients.

According to the present invention, term " carrier ", which refers to, can be combined with reactive compound or combines to make it easier for being administered to object（Such as plant, crop or careless class）Natural or synthetic organic or inorganic compound.Therefore, the carrier is preferably inert, at least should be agronomically acceptable.The carrier can be solid or liquid.Suitable carrier can for it is following those：

Such as ammonium salt and natural rock powder, such as kaolin, clay, talcum, chalk, quartz, attapulgite, montmorillonite or diatomite, synroc powder such as finely divided silica, aluminum oxide and silicate, oily wax, solid fertilizer, water, the preferred butanol of alcohol, organic solvent, mineral and vegetable oil and its derivative.

The suitable solid carrier for particle is：For example, natural rock such as calcite, marble, float stone, sepiolite, the dolomite crushing and be classified, and the inorganic particle with organic dust synthesis particle, and organic substance such as paper, sawdust, coconut husk, corncob and tobacco stem；

Liquid gaseous diluent or carrier mean to be at ambient temperature and pressure gaseous liquid, for example, aerosol propellant, such as halogenated hydrocarbons and butane, propane, nitrogen and carbon dioxide.

Adhesive such as carboxymethyl cellulose, natural and synthesis powder, particle or latex shaped polymer such as gum arabic, polyvinyl alcohol, polyvinyl acetate and natural phospholipid can be used in the preparation（Such as cephalin and lecithin）And synthetic phospholipid.Other additives can be the mineral or vegetable oil and wax being optionally modified.

Suitable liquid-carrier is, for example, water, polarity and nonpolar organic chemistry liquid, such as aromatic hydrocarbons and non-aromatic hydro carbons（Such as paraffin, alkylbenzene, alkylnaphthalene, chlorobenzene）, alcohol and polyalcohol（If appropriate, its can also be substitution, etherificate and/or esterification）, ketone（Such as acetone, cyclohexanone）, esters（Including fat and oil）With polyethers, unsubstituted and substituted amine, amide-type, lactams（Such as N- alkyl pyrrolidones）With lactone, sulfone class and sulfoxide type（Such as dimethyl sulfoxide (DMSO)）.

If liquid-carrier used is water, such as organic solvent is it is also possible to use as cosolvent.Suitable liquid flux mainly has：Aromatic hydrocarbons such as dimethylbenzene, toluene or alkylnaphthalene；Chlorinated aromatic hydrocarbons and chlorinated aliphatic hydrocarbon, such as chlorobenzene, vinyl chloride or dichloromethane；Aliphatic hydrocarbon, such as hexamethylene or paraffin such as petroleum distillate；Mineral and vegetable oil；Alcohol such as butanol or ethylene glycol, and their ether and ester；Ketone such as acetone, methyl ethyl ketone, methyl iso-butyl ketone (MIBK) or cyclohexanone；Intensive polar solvent such as dimethyl sulfoxide (DMSO)；And water.

The Pesticidal combination of the present invention can also include surfactant.The surfactant can for ion or nonionic emulsifying agent, dispersant or wetting agent, or these surfactants mixture.It can be mentioned that, for example, the condensation polymer of polyacrylate, lignosulphonates, benzene sulfonate or naphthalene sulfonate, oxirane and fatty alcohol or aliphatic acid or fatty amine, fortified phenol（Particularly alkylphenol or aryl phenol）, the salt of esters of sulfosuccinic acids, taurine derivatives（Particularly alkyltaurate）, polyoxyethylene alcohol or the phosphate of phenol, the fatty acid ester of polyalcohol and the compounds of this invention containing sulfate radical, sulfonate radical or phosphonate functional group derivative, such as alkylaryl polyglycol ether, alkylsulfonate, alkyl sulfate, arylsulphonate, protein hydrolysate and methylcellulose.

Suitable emulsifying agent and/or dispersant are：For example, nonionic or anion emulsifier, such as polyoxyethylene fatty acid ester, polyoxyethylene aliphatic alcohol ether；Suitable dispersant is nonionic and/or ionic species, is selected from alcohol POE and/or POP ether, acid and/or POP or POE esters, alkyl-aryl-group and/or POP or POE ethers, fat and/or POP-POE adducts, POE and/or POP polyol derivatives, POE and/or POP/ sorbitans or sugared adduct, alkyl or aryl sulfate, sulfonate and phosphate or corresponding PO ethers adduct.In addition, suitable oligomer or polymer, for example based on single vinyl monomer, acrylic acid, EO and/or PO or its with for example（It is polynary）Alcohol or（It is polynary）The combination of amine.Lignin and its sulfonic acid can also be used, common and modified cellulose, aromatic series and/or aliphatic sulfonic and their adducts with formaldehyde.Suitable dispersant such as methylcellulose and lignin sulfite waste liquor.

Optionally, other annexing ingredients, such as protecting colloid, adhesive, thickener, thixotropic agent, bleeding agent, stabilizer, screening agent can also be included.More commonly, reactive compound of the invention can be combined with any solid or liquid additive, and this meets conventional formulating techniques.

The combination or composition of the present invention can be used directly, used using dosage form or as type of service prepared therefrom, such as aerosol, suspending agent, microcapsulated granule, granula subtilis, flowable concentrate, ready to use solution agent, pulvis, missible oil, aqueous emulsion, oil emu, big granula, fine granule, oil dispersed pulvis, the miscible mobility concentrate of oil, oily miscible liquids, foaming agent, paste, suspending concentrate, suspension emulsion, solubility concentrate, soluble powder, granule, water-soluble granular and/or tablet, water solube powder, wettable powder, the natural or synthetic material impregnated through reactive compound, microcapsules and water-dispersible granule in polymeric material.In preferred embodiments, the agrochemical composition is missible oil, suspending agent, water dispersible granules, wettable powder, suspension emulsion and/or microcapsule suspending agent.

The reactive compound can be mixed and prepared by the preparation of the present invention by known way with conventional additives.For example conventional extender of the conventional additives and solvent or diluent, emulsifying agent, dispersant, and/or adhesive or fixative, wetting agent, waterproofing agent, if desired, can also include drier and colouring agent, stabilizer, pigment, defoamer, preservative, thickener, water and other processing aids.

These compositions not only include that pending object can be applied to immediately by suitable equipment such as spraying or dusting equipment, and are additionally included in the concentration commercial composition for needing to be diluted before being applied to object.

The preparation suitable for applying can be made in the composition of the present invention in the form of the composition of its active compound component, can also be applied in the form of the combination of the commercial preparation of its suitable dosage.It can also be administered in combination with other activating agents, other agents such as insecticide, attractant, bactericidal agent, bactericide, acaricide, nematicide, fungicide, growth regulator, herbicide, safener, fertilizer or semiochemical etc..

The Pesticidal combination of the present invention is applied to the animal pest that preventing and treating is found in terms of agricultural, animal health, forest, garden and Relexing device, the protection of Stored Product and health, while display tolerance, hypotoxicity to warm blooded species and the good Environmental compatibility good to plant.Kind to normal sensitive and resistance is active, active to all or special stage of development.Above-mentioned insect includes：

From Isopoda, such as damp worm（Oniscus aselluse）, pillworm（Armadillidium vulgare）, and spot pillworm（Porcellio scaber）.

From Diplopoda, such as Blaniuus guttulatus.

From chilopoda, such as centipede（Geophilus carpophagus）With common house centipede dragonfly（Scutigera spp.）.

From Symphyla, such as clean symphilid（Scutigerella immaculate）.

From Thysanoptera, such as silverfiss（Lepisma saccharina）.

From Collembola, such as Onychiurus arcticus（Onychiurus armatus）.

From Orthoptera, such as house cricket found in a kitchen（Acheta domesticus）, Gryllotalpa spp（Gryllotalpa spp.）, tropical migratory locusts（Locusta migratoria migratorioides）, the negative locust category of long volume（Melanoplus spp.）, and desert locust（Schistocerca gregaria）.

From Blattaria, such as oriental cockroach（Blatta orientalis）, American cockroach（ Periplaneta Americana）, leucophaea maderae（Leucophaea maderae）, Groton bug（Blattella germanica）.

From Dermaptera, such as European earwig（Forficula auricularia）.

From Isoptera, such as Reticulitermes.

From Anoplura, such as body louse（Pediculus humanus corporis）, blind pediculus, and long volume Pediculus, Trichodectes, Damalinia.

From Thysanoptera, such as greenhouse Hercinothrips spp（Hercinothrips femoralis）, cotton thrips（Thrips tabaci）, Thrips palmi and Frankliniella accidentalis.

From Heteroptera, such as Eurygasterspp belongs to, middle red cotton bug（ Dysdercus intermedius）, beet plan lace bug（ Piesma quadrata）, the smelly stinkbug in temperate zone（ Cimex lectularius）, red abdomen hunts stinkbug（ Rhodnius prolixus）And Triatoma. 

From Homoptera, such as wild cabbage aleyrodid（ Aleurodes brassicae）, Bemisia tabaci（Bemisia tabaci）, Trialeurodes vaporariorum Westwood（ Trialeurodes vaporariorum）, cotten aphid（ Aphis gossypii）, brevicoryne brassicae（ Brevicoryne brassicae）, the hidden knurl volume aphid of tea deer（ Cryptomyzus ribis）, black bean aphid（Brevicoryne brassicae）, apple aphid（Aphispomi）, apple aphid（ Eriosoma lanigerum）, mealy plum aphid（Hyalopterus arundinis）, grape phylloxera（Phylloxera vastatrix）, , Pemphigus, grain aphid (Macrosiphum avenae), knurl volume Aphis, hops knurl volume aphid (Phorodon humuli), grain Rhopalosiphum spp (Rhopalosiphum padi), leafhopper belongs to, Euscelisbilobatus, rice green leafhopper (Nephotettix cincticeps), brown apricot scale (Lecaniumcorni), olive helmet (Saissetia oleae), rice small brown rice planthopper (Laodelphaxstriatellus), brown back rice plant hopper (Nilaparvata lugens), California red scale (Aonidiel1a aurantii), oleander circle a red-spotted lizard (Aspidiotus hederae), mealybug belongs to and Psylla spp.

From Lepidoptera, such as pink bollworm (Pectinophora gossypiella), loose looper (Bupalus piniarius), winter geometrid moth (Chemimatobia brumata), Lithoclletis blancardela, cherry ermine moth（Hyponomeuta padella）,Diamondback moth (Plutella xylostel1a),Tent caterpillar (Malacosoma neustria),Pornography and drug moth (Euproctis chrysorrhoea),Euproctis,Cotton shot hole of leaf lyonetid (Bucculatrix thurberiella),Tangerine leaf miner (Phyllocnis tiscitrella),Agrotis,Cutworm belongs to,Brown Noctua,Earias insulana (Eariasinsulana),Noctua,Lopper worm (Mamestra brassicae),Small noctuid (Panolis flammea),Noctua,Cabbage looper (Trichoplusiani),The slow-witted moth-eaten moth (Carpocapsa pomonella) of apple,Pier,Snout moth's larva belongs to Pyrausta nubilalis,Anagasta kuehniella (Ephestia kuehniella),Rheum officinale snout moth's larva (Galleriamellonel1a),Bag casemaking clothes moth (Tineola bisselliella),Etting moth (Tineapell ionel1a),Brown oecophorid (Hofmannophilapseudospretella),Yellow tail leaf roller (Cacoecia podana), Capua reticulana ,Choristoneura fumigerana (Choristoneura fumiferana),The slow-witted moth-eaten moth (Clysia ambiguel1a) of grape,Tea yellow leaf curl moth (Homona magnanima),The green leaf roller of oak (Tortrix viridana),Roll up snout moth's larva category,Oulema oryzae (Oulema oryzae).

From coleoptera, such as furniture death watch beetle (Anobium punctatum), lesser grain borer (Rhizopertha dominica), Bruchidius obtectus, bean weevil (Acanthoscelides obtectus), house longhorn beetle (Hylotrupes bajulus), alder purple flea beetle (Agelastica alni), colorado potato bug (Leptinotarsadecemlineata), horseradish ape is chrysomelid (Phaedon cochleariae), chrysomelid category, rape orchid flea beetle (Psylliodes chrysocephala), mexican bean ladybird (Epi1achna varivestis), hidden wing first category, saw chest ostomatid (Oryzaephilus surinamensis), weevil belongs to, Sitophilus, vine black ear is as (Otiorrhynchus sulcatus), banana spider base weevil (Cosmopolites sordidus), wild cabbage English weevil (Ceuthorrhynchusassimilis), alfalfa weevil (Hypera postica), khapra beetle belongs to, spot khapra beetle belongs to, Anthrenus, the moth-eaten category of hair, powder moth category, pollen beetle (Meligethes aeneus), spider

First belongs to, golden yellow ptinid (Niptus hololeucus), wheat ptinid (Gibbiumpsylloides), Tribolium, Cabot's Tragopan (Tenebrio molitor), click beetle belongs to, acupuncture needle Eimeria, angle cockchafer (Melolontha melolontha), chafer in June (Amphimallon solstitialis), brown New Zealand's rib wing gill cockchafer (Costelytrazealandica) and Lissorhoptrusoryzophilus (Lissorhoptrus oryzophilus).

From Hymenoptera, such as Neodiprion spp belongs to, tenthredinidae, field ant category, MonomoriumMayr (Monomorium pharaonis) and Vespa.

From Diptera, such as Aedes, spot Anopheles, Culex, drosophila yellow gorilla (Drosophilamelanogaster), Musca, male servant fly belongs to, calliphora erythrocephala (Calliphoraerythrocephala), lucilia sericata belongs to, Carysomyia, cuterbrid belongs to, Gasterophilus, Hippobosca, chela fly belongs to, nose fly belongs to, Hypoderma, Pituophis, Tannia belongs to, Bibio hortulanus, Sweden's straw rope (Oscinella frit), wheat fly belongs to, beet fly (Pegomyiahyoscyami), Mediterranean fruitfly (Ceratitis capitata), dacus oleae (Dacusoleae) and European daddy-longlegs (Tipula paludosa), Hylemyia, and Hippelates.

From Siphonaptera, the holy mouse of such as Xenopsyllacheopis (Xenopsylla cheopis) and angle leaf.

From Arachnoidea, such as scorpion (Scorpio maurus), black widow (Latrodectus mactans), Acarus siro (Acarus siro), hidden category, blunt port category, Dermanyssus gallinae (Dermanyssys gallinae), tea deer goitre mite (Eriophyesribis), citrus rust mite (Phyllocoptruta oleivora), Boophilus, carrapato belongs to, Amblyomma, Hyalommaspp, Isodesspp, Acarus tritici belongs to, ginger mite belongs to, Sarcoptesspp, the compacted category of line, Bryobia praetiosa (Bryobia praetiosa), red spider belongs to, the compacted category of red autumnal leaves, sharp tenthredinidae, short whisker Acarapis.

Parasitic plant nematode includes such as Pratylenchus, Radopholus similis Throne (Radopholus similis), fuller's teasel Ditylenchus dipsaci (Ditylenchus dipsaci), Tylenchulus Semipenetrans (Tylenchulus semipenetrans), Heterodera, ball Heterodera, Meloidogyne, Aphelenchoides, minute hand Turbatrix, Xiphinema, and burr Turbatrix, remote spring dragonfly category.

A kind of Pesticidal combination containing paichongding and cypermethrin of the present invention is particularly suitable for use in preventing and treating " biting " insect, and these insects specifically include following insect：

From Lepidoptera,Such as pink bollworm (Pectinophora gossypiella),Loose looper (Bupalus piniarius),Winter geometrid moth (Cheimatobia brumata),Lithocolletis blancardel1a ,Cherry ermine moth (Hyponomeuta padella),Diamondback moth (Plutella xylostella),Tent caterpillar (Malacosoma neustria),Pornography and drug moth (Euproctis chrysorrhoea),Euproctis,Cotton shot hole of leaf lyonetid (Bucculatrix thurberlella),Tangerine leaf miner (Phyllocnistiscitrella),Agrotis,Cutworm belongs to,Brown Noctua,Egyptian complete just brill (Eariasinsulana),Noctua,Lopper worm (Mamestra brassicae),Small noctuid (Panolisflammea),Noctua,Powder pattern moth (Trichoplusiani),Carpocapsa pononella (Carpocapsa pomonella),Pier,Snout moth's larva belongs to, Pyrausta nubilalis ,Anagasta kuehniella (Ephestia kuehniella),Rheum officinale snout moth's larva (Gal1eriamellonella),Bag casemaking clothes moth (Tineola bisselliella),Etting moth (Tineapellionella),Brown oecophorid (Hofmannophila pseudospretella),Yellow tail leaf roller (Cacoecia podana), Capua reticulana ,Choristoneura fumigerana (Choristoneura fumiferana),The slow-witted moth-eaten moth (Clysia ambiguella) of grape,Tea yellow leaf curl moth (Homona magnanima),The green leaf roller of oak (Tortrix viridana),Roll up snout moth's larva category,Oulema oryzae (Oulema oryzae).

From coleoptera,Such as furniture death watch beetle (Anobium punctatum),Lesser grain borer (Rhizopertha dominica), Bruchidius obtectus ,Bean weevil (Acanthoscelides obtectus),House longhorn beetle (Hylotrupes bajulus),Alder purple flea beetle (Agelastica alni),Colorado potato bug (Leptinotarsa decemlineata),Horseradish ape is chrysomelid (Phaedon cochleariae),Chrysomelid category,Rape orchid flea beetle (Psylliodes chrysocephala),Mexican bean ladybird (Epilachnavarivestis),Hidden wing first category,Saw chest ostomatid (Oryzaephilus surinamensis),Weevil belongs to,Sitophilus,During vine black ear beak (Otiorrhynchus sulcatus),Banana spider base weevil (Cosmopolites sordidus),Wild cabbage English weevil (Ceuthorrhynchus assimilis),Alfalfa weevil (Hypera postica),Khapra beetle belongs to,Spot khapra beetle belongs to,Anthrenus,The moth-eaten category of hair,Powder moth category,Pollen beetle (Meligethes aeneus),Ptinus,Golden yellow ptinid (Niptus hololeucus),Wheat ptinid (Gibbium psylloides),Tribolium,Cabot's Tragopan (Tenebrio molitor),Click beetle belongs to,Acupuncture needle Eimeria,Angle cockchafer (Melolontha melolontha),Chafer in June (Amphimallon solstitialis),Brown New Zealand's rib wing gill cockchafer,Angle cockchafer (Costelytra zealandica) and Lissorhoptrusoryzophilus (Lissorhoptrus oryzophilus).

A kind of Pesticidal combination containing paichongding and cypermethrin of the present invention is particularly suitable for use in preventing and treating " sucking " insect, and these insects specifically include following insect：

From Homoptera,Such as wild cabbage aleyrodid (Aleurodes brassicae),Bemisia tabaci (Bemisia tabaci),Trialeurodes vaporariorum Westwood (Trialeurodes vaporariorum),Cotten aphid (Aphis gossypii),Brevicoryne brassicae (Brevicoryne brassicae),The hidden knurl volume aphid of tea deer (Cryptomyzus ribis),Black bean aphid (Aphis fabae),Apple aphid (Aphispomi),Apple aphid (Eriosoma lanigerum),Mealy plum aphid (Hyalopterusarundinis),Grape phylloxera (Phylloxera vastatrix),Goitre cotten aphid belongs to,Grain aphid (Macrosiphum avenae),Knurl volume Aphis,Hops knurl volume aphid (Phorodonhumuli),Grain Rhopalosiphum spp (Rhopalosiphum padi),Leafhopper belongs to, Euscelisbilobatus ,Rice green leafhopper (Nephotettix cincticeps),Brown apricot scale (Lecaniumcorni),Olive helmet (Saissetia oleae),Rice small brown rice planthopper (Laodel phaxstriatellus),Brown back rice plant hopper (Nilaparvata lugens),California red scale (Aonidiella aurantii),Oleander circle a red-spotted lizard (Aspidiotus hederae),Mealybug belongs to and Psylla spp.

As a further improvement on the present invention, described insecticides are particularly suitable for preventing and treating homoptera pest, lepidoptera pest and arachnoide pest.Application particularly in froghopper, leafhopper, horned frog, plant hopper, plant hopper, wood louse, aleyrodid, aphid, coccid, bollworm, tetranychid, thrips, stinkbug silk worm.

It can directly be carried out, or be carried out by acting on its environment, habitat or storage areas by usual processing method, the usual processing method is such as by pouring（Dipping）, drip irrigation, spraying, evaporation, be atomized, broadcast sowing, dusting, foaming, the mode such as coating；Or it is used as the solvable pulvis handled for seed or rice shoot, liquid agent, slurry；And pass through dry-cure, slurry processing, liquid handling.Also the compound can be applied by ultra-low volume method, or the compound or composition are injected in soil in itself.

The method of the present invention is additionally provided to separate, sequentially or simultaneously the reactive compound is administered in combination in mode.In one embodiment, paichongding and cypermethrin is administered simultaneously.In another embodiment, successively using paichongding and cypermethrin.In still another embodiment, separate administration paichongding and cypermethrin.

It is common and favourable that composition or the activating agent combination of the present invention is generally applied with following dosage：

- for leaf portion processing：0.1-10000 g/ha, preferably 10-1000g/ha, more preferably 50-300g/ha；For impregnating or instiling and apply, the dosage even can also be reduced, particularly when applying inert base such as asbestos or perlite；

- for Seed Treatment：2-200 g/100kg seeds, preferably 3-150g/100kg seeds；

- for soil treatment：0.1-10000g/ha, preferably 1-5000g/ha.

Above-mentioned dosage is only general exemplary dose, and those skilled in the art can adjust rate of application according to actual conditions and needs especially in accordance with the property and insect pest situation of pending plant or crop during actual administration.

The activating agent of the present invention has good plant compatibility, and suitable for control insect, particularly insect, acarid, nematode, and fungi, rodent, microorganism etc., it preferably acts as the composition for leaf processing, soil treatment and seed, rice shoot processing.

According to the present invention it is possible to handle each several part of all plant and plant.Plant is understood to mean that all plant and plant population as desired and undesirable wild plant or crop (crop for including spontaneous growth) herein.Crop can be the plant obtained by conventional breeding and optimum seeking method; or the plant of the combination acquisition by biotechnology and genetic engineering method or these methods, including genetically modified plants and the Plant cultivars including that can or can not be protected by plant breeder's certificate.Plant parts are understood to mean that all part and plant organ such as seedling, leaf, Hua Hegen above and below the ground, and the example that can be mentioned that is leaf, pin, stem, dry, flower, fructification, fruit and seed and root, stem tuber and rhizome.The part of plant also includes the plant after harvest and vegetative propagation and case of propagation material, such as seedling, stem tuber, rhizome, transplants and seed.

As described above, all plants and its part can be handled according to the present invention.In preferred embodiments, handled wild plant species and Plant cultivars or by standard biologic breeding method as hybridization or protoplast fusion obtain plant variety and its part.In a more preferred embodiment, handled by genetic engineering (genetically modified plants obtained if necessary with reference to conventional method (Genetically Modified Organisms) and Plant cultivars and its part.

According to the present invention, the plant for the Plant cultivars being commercially available in all cases or in use is particularly preferably handled.

It is emphasized that the Pesticidal combination of the present invention is used for effect particularly advantageous during such as following plant：Cereal such as wheat,Oat,Barley,Spelt (spelt),Triticale and rye,And corn,Jowar and chestnut,Rice,Sugarcane,Soybean,Sunflower,Potato,Cotton,Rape (oil seed rape),Canola (canola),Tobacco,Beet,Fodder beet,Asparagus,Hops and fruit bearing plant (including the operatic circle such as apple and pears,Drupe such as peach,Honey peach,Cherry,Plum,Apricot,Cedra fruits such as orange,Grape cypress,Bitter orange,Twist Lu,Cumquat,Citrus and Sa Mo tangerines,Nut such as pistachio,Almond,Walnut and pecan,Tropical fruit (tree) such as mango,Papaya,Pineapple,Nipa palm and banana,And grape) and vegetables (including leaf vegetables such as lettuce,Corn salad,Fennel,Leaf lettuce,Celery lettuce,Swiss chard,Spinach and salad use witloof,Wild cabbage such as cauliflower,Broccoli,Chinese leaf,Brassica oleracea (L.) convar. acephalavar. sabellicaL. (savoys,Collard),Kohlrabi,Brussels sprout,Red cabbage,White cabbage and savoy,Fruit vegetables such as eggplant,Cucumber,Capsicum,Edible squash,Tomato,Bush pumpkin and corn,Root vegetables such as celeriac,Rape,Carrot includes yellow cultivars,Wild radish class includes Raphanus sativus var. niger and Raphanus sativus var.radicula,Beet,Celery,Legume such as pea and soybean,And allium vegetables such as leek and onion).

According to plant variety or Plant cultivars, its position and growth conditions (soil, weather, growth period, food), it can also produce super according to the processing of the present invention plus be acted on (" collaboration ").So, for example reduction consumption and/or widen activity profile and/or increase according to active, the more preferable plant growth of material workable for the present invention and composition, enhancing the tolerance of high temperature or low temperature, enhancing are bloomed to the tolerance of dry early, water or soil salt content, increase performance, be easier to harvest, hasting of maturity, higher harvest yield, better quality and/or harvest the machinability of higher nutritive value, more preferable storage stability and/or harvest product of product and be all possibly realized, that is out the effect of actual desired.

The Pesticidal combination of the present invention not only to plant insect, sanitary insect pest and store pest effectively, it is and also effective to parazoon (vermin) such as hard tick, soft ticks, itch mite, pyemotes ventricosus, fly (Ci Shi and lick formula), parasitic fly larvae, lice, head louse, bird lice and flea in terms of animal doctor.These parasites include：

Anoplura, such as Haematopinus, Linognathusspp, Pediculus, Phtirus category, pipe Pediculus；

Mallophaga and Amblycera and thin angle suborder, such as filoplume Pediculus, Menopon category, huge Linognathus, Trichodectes, Werneckiella category, Lepikentron category, Damalinia, Trichodectes, Felicola；

Diptera and Nematocera and Brachycera, such as Aedes, Anopheles, Culex, Simulium, Eusimulium, owl midge, Lutzomyia category, Bitting midge, Chrysops, knurl Gadfly, Atylotus, Gadfly, Chrysozona, Philipomyia category, honeybee Hippobosca, Musca, Hydrotaea, chela fly belongs to, Haematobiaspp, and fly does not belong to, Fannia, Glossina, Calliphora, Lucilia, Carysomyia, Wohlfahrtia, Sarcophaga, Oestrus, Hypoderma, Gasterophilus, Hippobosca, Lipoptena category, Melophagus；

Anoplura, such as Pediculus, first flea category, Xanthopsyllacheopis mouse, Ceratophyllus；

Heteroptera, such as Cimex, Triatomaspp, red abdomen hunt Toona, wholecircle Toona；

Blattaria, such as oriental cockroach, American cockroach, Groton bug, blattaria category；

Acarina and rear valve suborder and Mesostigmata, such as sharp port category, Ornithodoros, residual beak tick category, Isodesspp, Amblyomma, Boophilus, Dermacentor, Haemophysalis category, Hyalomma, Rh, Dermanyssus, the sharp mite category of thorn, Pneumonyssus, Sternostoma, Varroa；

Spoke mite suborder (preceding valve suborder) and flour mite mesh (Astigmata), such as honeybee Tarsonemus, Cheyletiella, fowl chela li mite category, Myobia, Psorergates, Demodex, Trombidium, yak mite belongs to, Tyroglyphus, Tyrophagus, Caloglyphus, mite belongs under neck, wing mite category, Psoroptesspp, Psoroptes, Notoedres, Sarcoptesspp, scab mite category, lump mite belongs to, Cytoleichus, epithelium mite category.

The active compound composition of the present invention applies also for the arthropod of preventing and treating invasion and attack agricultural animals such as ox, sheep, goat, horse, pig, donkey, camel, buffalo, rabbit, chicken, turkey, duck, goose, honeybee, other domestic animals such as dog, cat, cage bird, sight, reward fish and so-called experimental animal such as hamster, cavy, rat and mouse.By preventing and treating these arthropods, when should be able to reduce dead and reducing of the productivity (for meat, milk, wool, animal skin, egg, honey etc.), so more economical and simple animal husbandry can be obtained by using the Pesticidal combination of the present invention.

In terms of the Insecticidal combinations material of the present invention is used for animal doctor in known manner, pass through the enteral administration in the form of such as tablet, capsule, potus, draught, granule, paste, bolus, feeding method, suppository, for example, by injecting (intramuscular, subcutaneous, intravenous, intraperitoneal etc.), implant Parenteral administration, nose administration, for example to impregnate or soak, spray, pour, spot printing, washing, percutaneous dosing in the form of dusting, and pass through the mechanograph containing reactive compound such as necklace, ear tag, tail tag, limb girdle, halter rope, printer etc..

When for ox, poultry, family's richness etc., Pesticidal combination can contain 1-80wt% reactive compounds as preparation (such as pulvis, emulsion, flowable), directly or after 100-10000 times of dilution apply, or can be used as chemical immersion.

Moreover, it has been discovered that the effective insecticidal action of insect of the Pesticidal combination of the present invention to destruction industrial materials.

Propose as example and preferably following insect, but not limited to this：

Coleoptera such as North America house longhorn beetle (Hyloptrupes bajulus), green brave longicorn (Chlorophorus pilosis), furniture death watch beetle, dead material death watch beetle is reported (during Xestobiumrufovillosu, class wing death watch beetle (Ptilinus pecticornis), Dendrobium pertinex, loose bud branch death watch beetle (Ernobius mol1is), loose product death watch beetle (Priobiumcarpini), Lyctus brunneus Stephens (Lyctus brunneus), powder moth (Lyctus africanus), southern powder is moth-eaten (Lyctus planicollis), quercitron moth (Lyctus linearis), powder moth (Lyctus pubescens), chest powder moth (Trogoxylon aequale), minthea rugicollis (Minthesr ugicollis), material bark beetle belongs to, wood strip bark beetle belongs to, coffee is black long moth-eaten (Apa temonachus), Bostrychus capucins, brown different long wing is moth-eaten (Heterobostrychusbrunneus), spine length moth category, bamboo pole powder length moth (Dinoderus minutus).

Dermaptera, such as blue black wood wasp (Sirex juvencus), the big wood wasp of dragon spruce (Urocerusgigas), Urocerus gigas toiganus (Urocerus gigas taignus), big wood wasp (Urocerus augur).

Termite, such as kalotermitid (Kalotermes flavicollis), numb head heap sand termite (Cryptotermes brevis), the Indian-Pakistani different termite of structural wood (Heterotermes indicola), American-European reticulitermes flavipe (Reticulitermes flavipes), reticulitermes flavipe (Reticulitermes santonensis), reticulitermes flavipe (Reticuli termeslucifugus), Mastotermes darwiniensis (Mastotermes darwiniensis), Nevada Gu termite (Zootermopsis nevadensis), Workers of Coptotermes formosanus Shiraki (Coptotermesformosanus).

Thread tail mesh, such as Lepisma saccarina (Lepisma saccharina).

Industrial materials herein are understood to mean that non-living material such as preferred polymers, adhesive, glue, paper and plate, leather, timber, timber-work and coating.The particularly preferred timber of material and woodworking article of insect infestations to be protected it from.

Can with Pesticidal combination of the present invention or the mixture containing said composition protection timber and woodworking article be understood to mean that for example：

Construction timber, wooden frame, railroad tie, bridge member, breakwater, wooden vehicles, box, pallet, container, phone mast, timber partition, wooden window and door, glued board create card, joinery, or be generally used for building construction or the joiner's timber-work of building.

Pesticidal combination can be used as former state, in the form of concentrate or conventional formulation such as pulvis, granule, solution, suspending agent, emulsion or paste.

Above-mentioned preparation can be prepared in a way known, for example by by reactive compound and at least one solvent or diluent, emulsifying agent, dispersant and/or adhesive or fixative, waterproofing agent, need when drier and UV stabilizer and colouring agent and pigment and other processing aids when needing mix.

Pesticidal combination or concentrate for protecting timber and timber-work contain the reactive compound of the invention that concentration is 0.0001-95wt%, particularly 0.01-60wt%.

The consumption of composition or concentrate depends on the kind and quantity and medium of insect.Optimum amount in all cases can be determined by dispenser campaign, but be generally sufficient according to the reactive compound for the materials'use 0.0001-20wt%, preferably 0.001-10wt% to be protected.

The Pesticidal combination of the present invention is also applied for preventing and treating the animal pest of closing space, particularly insect, spider and acarid, the closing space such as house, factory floor, office, cabin etc..They can be used in domestic insecticide products preventing and treating these insects, and they are to sensitive and resistance kind and to all stages of development active.These insects include：

Scorpionida, such as pincers exhaust (Buthus occitanus).

Acarina, such as adobe tick, stick up edge sharp-edged tick, Bryobia, Dermanyssus gallinae, family and eat sweet mite, tampan tick, brown dog tick, trombiculid (Trombicula alfreddugesi), Neutrombicula autumnalis, dermatophagoides pteronyssinus, dust mite.

Araneida, such as cockle spider section, Yuan Zhu sections.

Opiliones, for example, intend scorpion class (Pseudoscorpiones chelifer), Pseudoscorpiones cheiridium, Opiliones phalangium.

Isopoda, such as damp worm, pillworm.

Times sufficient mesh, for example, have a zebra land, mountain cricket Eimeria.

Lip foot mesh, such as Scolopendra.

Zygentoma mesh, such as comb silverfish category, Lepisma saccarina, Lepismodes inquilinus.

Blattaria, such as oriental cockroach, Groton bug, Blatella (Bl a t t el1a asahinai), leucophaea maderae, angle abdomen Lian category, wood Lian category, Australian cockroach, American cockroach, Periplanetabrunnea, Peroplaneta fluligginosa, long hair blattaria.

Saltatoria, such as family Shuai.            

Dermaptera, such as European earwig.

Isoptera, such as kalotermitid category, Reticulitermes.

Worm mesh, such as Lepinatus category, powder breathe heavily Eimeria.

Coleoptera, such as Anthrenus, fur moth category, khapra beetle category, long head lesser grain borer, hidden instep cuckoo Eimeria, Ptinus, lesser grain borer, grain weevil, rice weevil, sitophilus zea-mais, Stegobium paniceum.

Diptera, such as Aedes aegypti, aedes albopictus, Aedes taeniorhynchus, Anopheles, calliphora erythrocephala, great number sarcophagid, Culex quinquefasciatus, northern house, Culex tarsalis, stay fly category, Fannia canicularis, housefly, Bai Ling category, sarcophagid (Sarcophaga carnaria), Simulium, male servant chela fly, daddy-longlegs (Tipula paludosa).

Lepidoptera, such as lesser wax-moth, galleria mellonella waxmoth, India Gu phycitid, rain moth, bag rain moth, Tineolabisselliella.

Siphonaptera, such as dog comb head lices, Ctenocephalides felis felis, humanlice, chigo, Xanthopsyllacheopis.

Hymenoptera, for example, blazon hunchbacked ant, bright hair ant, black wool ant, Lasius umbratus, MonomoriumMayr, Paravespula category, Pavement Ant.

Anoplura, such as head louse, body louse, crab louse.

Heteroptera, such as cimex hemipterus, bed bug, phodnius prolixus invade and harass vertebra and hunt stinkbug.

The Pesticidal combination of the present invention can be used as aerosol, without pressure spray product such as pump spraying and atomizer spray, automatic mist formation system, aerosol producer, foam, gel, evaporator product, liquid evaporator, gel and the film evaporator of the evaporating plate being made with cellulose or polymer, the evaporator of propeller driving, do not consume energy or passive type vapo(u)rization system, catch baby worm paper, catch moth bag and insect-catching glue, agent or pulvis are drawn as, in the bait formulation of sprinkling or bait formulation position.

A kind of good desinsection and mite killing worm effect containing paichongding and cypermethrin insecticide composition of the present invention is found in the following example.Although single reactive compound shows shortcoming in its effect, composition exhibits more than the effect of the simple plus sum of each effect.When the effect of active compound combinations exceedes the summation of the effect when each reactive compound is administered alone, there is the desinsection and acaricidal action of collaboration.So-called " Colby formula " can be used (referring to S.R. Colby in the predictive role of the particular combination of two kinds of reactive compounds, " Calculating Synergistic and Antagonistic Responses of Herbicide Combinations ", Weeds 1967,15,20-22) it is calculated as below:If

X is, when the use of consumption being mg/ha or kill rate during reactive compound A that concentration is mppm, to be expressed as accounting for the percentage of untreated control,

Y is, when the use of consumption being ng/ha or kill rate during reactive compound B that concentration is nppm, to be expressed as accounting for the percentage of untreated control,

E is, when the use of consumption being m and n g/ha or kill rate during reactive compound A and B that concentration is m and n ppm, to be expressed as accounting for the percentage of untreated control,

So

If actual desinsection fatal rate exceedes calculated value, the lethal effect of composition is super plus sum, that is, there is synergy.In this case, the kill rate actually observed must be over the value of the expection kill rate value (E) calculated using above-mentioned formula.

Example of formulations

Embodiment 1：The cypermethrin suspending agent of 2% paichongding+10%

Paichongding 2%

Cypermethrin 10%

Methyl naphthalene sulfonate formaldehyde condensate 10%

Xanthans 1%

Bentonite 1%

Glycerine 5%

Water complements to 100%

The each components such as active component, dispersant, wetting agent and water are well mixed according to the ratio of formula, the cypermethrin suspending agent of 2% paichongding+10% is obtained after ground and/or high speed shear.

 

The cypermethrin wettable powder of 2 20% paichongding of embodiment+4%

Paichongding 20%

Cypermethrin 4%

Lauryl sodium sulfate 2%

Sodium lignin sulfonate 5%

White carbon 10%

Kaolin complements to 100%

Active component, various auxiliary agents and filler etc. are mixed by the proportional components of formula, after ultra-fine pulverizer disintegrating, that is, the cypermethrin wettable powder of 20% paichongding+4% is obtained.

 

The aqueous emulsion of cypermethrin of 3 20% paichongding of embodiment+2%

Paichongding 20%

Cypermethrin 2%

1-METHYLPYRROLIDONE 15%

Calcium dodecyl benzene sulfonate 5%

Agriculture breast 600# 5%

Water complements to 100%

Active compound, solvent, emulsifying agent are added together, make to be dissolved into homogeneous oil phase；Water-soluble component and water are mixed to prepare aqueous phase；Under high velocity agitation, it is oil phase is mixed with water, the aqueous emulsion of cypermethrin of 20% paichongding+2% is made.

 

The cypermethrin water dispersible granules of 4 3.5% paichongding of embodiment+1.5%

Paichongding 3.5%

Cypermethrin 1.5%

Sodium lignin sulfonate 4%

Lauryl sodium sulfate 5%

Urea 5%

Kaolin complements to 100%

Active component, dispersant, wetting agent, disintegrant and filler are well mixed in the ratio of formula, by air-flow crushing into wettable powder, a certain amount of water mixing extruding is added and makes material.The cypermethrin water dispersible granules of 3.5% paichongding+1.5% are obtained after drying screening.

 

The cypermethrin suspending agent of 5 2% paichongding of embodiment+20%

Paichongding 2%

Cypermethrin 20%

Methyl naphthalene sulfonate formaldehyde condensate 10%

Xanthans 1%

Bentonite 1%

Glycerine 5%

Water complements to 100%

The each components such as active component, dispersant, wetting agent and water are well mixed in the ratio of formula, the cypermethrin suspending agent of 2% paichongding+20% is obtained after ground and/or high speed shear.

  

The cypermethrin suspending agent of 6 7.5% paichongding of embodiment+2.5%

Paichongding 7.5%

Cypermethrin 2.5%

Methyl naphthalene sulfonate formaldehyde condensate 5%

Xanthans 1%

Bentonite 1%

Glycerine 5%

Water complements to 100%

The each components such as active component, dispersant, wetting agent and water are well mixed in the ratio of formula, the cypermethrin suspending agent of 7.5% paichongding+2.5% is obtained after ground and/or high speed shear.

 

The cypermethrin wettable powder of 7 1% paichongding of embodiment+10%

Paichongding 1%

Cypermethrin 10%

Lauryl sodium sulfate 10%

Sodium lignin sulfonate 5%

White carbon 10%

Kaolin complements to 100%

Said components are mixed in proportion, and grinds, crush, wettable powder is prepared into.

 

The cypermethrin suspending agent of 8 25% paichongding of embodiment+1%

Paichongding 25%

Cypermethrin 1%

AEO sulfosuccinic acid monoesters disodium 10%

MODIFIED LIGNOSULPHONATE 5%

Xanthans 1%

Bentonite 1%

Glycerine 5%

Water complements to 100%

Above-mentioned each component is mixed in proportion, and through being sanded, is prepared into suspending agent.

 

The aqueous emulsion of cypermethrin of 9 30% paichongding of embodiment+20%

Oil phase：

Paichongding 30%

Cypermethrin 20%

Methyl oleate 38%

Polystyrene 3.7%

Aqueous phase：

Xanthans 0.07%

The sodium salt 1% of naphthalene sulfonic acids-formaldehyde condensation products of sulfonation

Bactericide 0.2%

Water complements to 100%

Paichongding and cypermethrin are dissolved in methyl oleate, polystyrene is added and obtains oil phase；Aqueous phase is obtained according to the component in formula is well mixed；Oil phase addition aqueous phase is obtained into aqueous emulsion under agitation.

 

The cypermethrin wettable powder of 10 20% paichongding of embodiment+1%

Paichongding 20%

Cypermethrin 1%

Sodium lignin sulfonate 4%

NaLS 2%

The silicic acid 1% of high degree of dispersion

Kaolin complements to 100%

Said components are mixed in proportion, and grinds, crush, wettable powder is prepared into.

 

The cypermethrin coated granule of 11 1% paichongding of embodiment+20%

Paichongding 1%

Cypermethrin 20%

Polyethylene glycol 3%

The silicic acid 1% of high degree of dispersion

Calcium carbonate complements to 100%

In a mixer, by levigate active component even spread to the carrier soaked by polyethylene glycol.Dust-free coated granules agent can be obtained in this way.

 

The cypermethrin wettable powder of 12 60% paichongding of embodiment+20%

Paichongding 60%

Cypermethrin 20%

Lauryl sodium sulfate 3%

Sodium lignin sulfonate 3%

White carbon 5%

Kaolin complements to 100%

Said components are mixed in proportion, and grinds, crush, wettable powder is prepared into.

 

The cypermethrin of 13 20% paichongding of embodiment+40% extrudes granule

Paichongding 20%

Cypermethrin 40%

Sodium lignin sulfonate 4%

Carboxymethyl cellulose 2%

Kaolin complements to 100%

Active component is mixed and ground with auxiliary agent, mixture is soaked with water.The mixture is extruded, then dried in the air stream.

 

The cypermethrin suspending agent of 14 1% paichongding of embodiment+25%

Paichongding 1%

Cypermethrin 25%

AEO sulfosuccinic acid monoesters disodium 10%

MODIFIED LIGNOSULPHONATE 5%

Xanthans 1%

Bentonite 1%

Glycerine 5%

Water complements to 100%

Above-mentioned each component is mixed in proportion, and through being sanded, is prepared into suspending agent.

 

The cypermethrin ZC of 15 10% paichongding of embodiment+2.5%

Atlox 4913                                        4%

Citric acid 0.05%

Catalyst 0.1%

Water 13%

Paichongding 10%

PAPI                                            1.35%

Solvesso 200                                     10%

Atlox4913                                        16%

Dispersant LFH 0.3%

Defoamer 0.16%

Urea 8.4%

Cypermethrin 2.5%

Water complements to 100%

By PAPI, the oil phase of cypermethrin and the formation of Solvesso 100 is added in the aqueous solution containing Atlox4913, forms emulsion.Then heat and be incubated 50^oCatalyst reaction is added under C 2 hours.The microcapsules of cypermethrin is obtained after cooling.

Atlox 4913, dispersant LFH, defoamer, urea, paichongding and water are mixed in proportion, and through being sanded, are prepared into suspending agent.

In the aqueous suspension agent that the microcapsules of obtained cypermethrin is added to paichongding, the cypermethrin ZC of 10% paichongding+2.5% is uniformly mixing to obtain.

 

The cypermethrin suspended emulsion of 16 5% paichongding of embodiment+2.5%

Paichongding 5%

Cypermethrin 2.5%

Solvesso 200                                        30%

Ethoxylated castor oil 4%

AEO sulfosuccinic acid monoesters disodium 10%

MODIFIED LIGNOSULPHONATE 5%

Xanthans 1%

Bentonite 1%

Glycerine 5%

Water complements to 100%

Cypermethrin is dissolved in Solvesso 200, ethoxylated castor oil is added, obtains the missible oil of cypermethrin；

By paichongding, AEO sulfosuccinic acid monoesters disodium, above-mentioned each component is mixed in proportion, and through being sanded, is prepared into suspending agent.

Oil phase containing cypermethrin is added in the suspending agent containing paichongding, suspended emulsion is obtained.

The permethrin milk oil of 17 2.5% paichongding of embodiment+2.5%

Paichongding 2.5%

Cypermethrin 2.5%

Ethoxylated castor oil 5%

Calcium dodecyl benzene sulfonate 3%

Solvesso100 complements to 100%

Above-mentioned each component is mixed, stirring is to obtaining transparent homogeneous phase.

 

The cypermethrin dashing agent of 18 0.5% paichongding of embodiment+0.5%

Biphenyl polyester 0.5%

Cypermethrin 0.5%

1-METHYLPYRROLIDONE complements to 100%

Above-mentioned each component is mixed, stirring is to obtaining transparent homogeneous phase.

 

The cypermethrin drops of 19 1% paichongding of embodiment+1%

Biphenyl polyester 1%

Cypermethrin 1%

Solvesso 100 complements to 100%

Above-mentioned each component is mixed, stirring is to obtaining transparent homogeneous phase.

 

The cypermethrin suspension seed-coating agent of 20 5% paichongding of embodiment+5%

Paichongding 5%

Cypermethrin 5%

AEO sulfosuccinic acid monoesters disodium 10%

MODIFIED LIGNOSULPHONATE 5%

Xanthans 1%

Bentonite 1%

Glycerine 5%

PVP-K30                                       1%

Water complements to 100%

Above-mentioned each component is mixed in proportion, and through being sanded, is prepared into suspension seed-coating agent.

The cypermethrin of 21 60% paichongding of embodiment+40%

Paichongding 60%

Cypermethrin 40%

Paichongding and cypermethrin are proportionally well mixed. 

Biological test example

After the pestsides synthesis of different cultivars, three kinds of type of action are typically exhibited：Summation action, synergistic effect and antagonism.But it is specially which kind of effect, it is impossible to predict, only just can know that by many experiments.Compound synergic is formulated well, due to significantly improving actual prevention effect, reduces the usage amount of agricultural chemicals, is the important means of integrated control disease so as to greatly delay the drug-fast generation speed of harmful organism.

 

Virulence test

Experiment 1

Subjects：Planthopper

Test method：Planthopper（Brown paddy plant hopper Nilaparvata lugens）Test method is referred to《Magnificent people's republic's agricultural industry criteria NY/T1154.7-2006》.Test worm is to pick up from the planthopper in field（Brown paddy plant hopper）Pupa, warm indoor rice seedlings raised for 3 generations, selected four age nymphs of uniformity, were pressed into storing rice seedling（Handled with cotton ball moisturizing）Diameter 12cm culture dish, connect per ware and anaesthetized nymph 30, often processing connects 4 culture dishes, sprayed with potter spray towers under 50PSI pressure, every time one ware of spray, per ware spraying liquid 3ml, after insect revives, treated culture dish is put into 12H/12H illumination boxs and cultivated, dead borer population is checked within 72 hours, the death rate is calculated.Equivalent clear water is sprayed in blank control, and statistical analysis is carried out with DPS data processors software, calculates the LC50 values of each medicament, activity of the reagent agent to test worm is evaluated with this.

The co-toxicity coefficient of compound drug（CTC values）Calculated by following equation：

In formula：ATI --- mixture surveys toxicity index；

S --- standard pesticide agent LC50, unit for milligrams per liter（mg/L）；

The LC50 of M --- mixture, unit for milligrams per liter（mg/L）；

TTI=TIA×PA+ TIB×PB

In formula：

TTI --- mixture theoretical toxicity index；

TIA --- A medicament toxicity index；

PA --- percentage composition of the A medicaments in mixture, unit is percentage（%）；

TIB --- B medicament toxicity index；

PB --- percentage composition of the B medicaments in mixture, unit is percentage（%）；

In formula：CTC --- co-toxicity coefficient；

ATI --- mixture surveys toxicity index；

TTI --- mixture theoretical toxicity index；

Table 1 is the toxicity test result of compound drug of the present invention and single medicament to planthopper

The proportioning of paichongding and cypermethrin is can be seen that 1 from form above:25~25:When in 1 scope, its co-toxicity coefficient to planthopper is all higher than 120, illustrates that both show as gain effect at mixture in the range of this, especially when both ratios are 5:When in 1, gain effect is especially prominent.

 

Experiment 2： 

Subjects：Eggplant aphid

Test method：Eggplant aphid.Test method is referred to《People's Republic of China (PRC) agricultural industry criteria NY/T1154.6-2006》.Test worm is to pick up from the aphid in eggplant field, the aphid of age uniformity is selected in laboratory, aphid is immersed into 5S in ready decoction, unnecessary decoction is drawn with filter paper, aphid is transferred under normal condition and raised, 4 repetitions are often handled, leaching worm 30 is often repeated, dead borer population is checked within 24 hours, the death rate is calculated.

Table 2 is the toxicity test result of compound drug of the present invention and single medicament to aphid

The proportioning of paichongding and cypermethrin is can be seen that 1 from form above:25~25：When in 1 scope, its co-toxicity coefficient to eggplant aphid is all higher than 120, illustrates that both show as gain effect at mixture in the range of this, especially when both ratios are 5：When 1, gain effect is especially prominent.

 

Experiment 3：

Subjects：Cabbage pieris

Test method：Test worm is to pick up from the cabbage caterpillar in wild cabbage field, the larva of uniformity is selected in laboratory, is put into blade-carrying culture dish, per the cephalont of ware 40, often handle 4 culture dishes, it is repeated 3 times, is sprayed with potter spray towers under 50PSI pressure, every time one ware of spray, per ware spraying liquid 3ml, then treated culture dish is put into 12H/12H illumination boxs and cultivated, check within 48 hours dead borer population, calculate the death rate.Equivalent clear water is sprayed in blank control.Statistical analysis is carried out with DPS data processors software, the LC50 values of each medicament is calculated, activity of the reagent agent to test worm is evaluated with this.

 

Table 3 is the toxicity test result of compound drug of the present invention and single medicament to cabbage pieris

The proportioning of paichongding and cypermethrin is can be seen that 1 from form above:25~25：When in 1 scope, its co-toxicity coefficient to cabbage pieris is all higher than 120, illustrates that both show as gain effect at mixture in the range of this, especially when both ratios are 1:When 5, gain effect is especially prominent.

 

Experiment 4：

Subjects：Tomato trialeurodes vaporariorum

Test method：Test worm is to pick up from the trialeurodes vaporariorum in tomato field, the larva of uniformity is selected in laboratory, is put into blade-carrying culture dish, per the cephalont of ware 40, often handle 4 culture dishes, it is repeated 3 times, is sprayed with potter spray towers under 50PSI pressure, every time one ware of spray, per ware spraying liquid 3ml, then treated culture dish is put into 12H/12H illumination boxs and cultivated, check within 48 hours dead borer population, calculate the death rate.Equivalent clear water is sprayed in blank control.Statistical analysis is carried out with DPS data processors software, the LC50 values of each medicament is calculated, activity of the reagent agent to test worm is evaluated with this.

 

Table 4 is the toxicity test result of compound drug of the present invention and single medicament to tomato trialeurodes vaporariorum

The proportioning of paichongding and cypermethrin is can be seen that 1 from form above:25~25：When in 1 scope, its co-toxicity coefficient to tomato trialeurodes vaporariorum is all higher than 120, illustrates that both show as gain effect at mixture in the range of this, especially when both ratios are 1:When 1, gain effect is especially prominent.

 

Experiment 5：

Subjects：Cucumber thrips

Test method：Test worm is to pick up from the thrips in cucumber field, the larva of uniformity is selected in laboratory, is put into blade-carrying culture dish, per the cephalont of ware 40, often handle 4 culture dishes, it is repeated 3 times, is sprayed with potter spray towers under 50PSI pressure, every time one ware of spray, per ware spraying liquid 3ml, then treated culture dish is put into 12H/12H illumination boxs and cultivated, check within 48 hours dead borer population, calculate the death rate.Equivalent clear water is sprayed in blank control.Statistical analysis is carried out with DPS data processors software, the LC50 values of each medicament is calculated, activity of the reagent agent to test worm is evaluated with this.

 

Table 5 is the toxicity test result of compound drug of the present invention and single medicament to cucumber thrips

The proportioning of paichongding and cypermethrin is can be seen that 1 from form above:25~25：When in 1 scope, its co-toxicity coefficient to cucumber thrips is all higher than 120, illustrates that both show as gain effect at mixture in the range of this, especially when both ratios are 1:When 1, gain effect is especially prominent.

 

Experiment 6：

Subjects：Papillosa

Test method：Test worm is to pick up from the stinkbug silk worm in lichee field, the larva of uniformity is selected in laboratory, is put into blade-carrying culture dish, per the cephalont of ware 40, often handle 4 culture dishes, it is repeated 3 times, is sprayed with potter spray towers under 50PSI pressure, every time one ware of spray, per ware spraying liquid 3ml, then treated culture dish is put into 12H/12H illumination boxs and cultivated, check within 48 hours dead borer population, calculate the death rate.Equivalent clear water is sprayed in blank control.Statistical analysis is carried out with DPS data processors software, the LC50 values of each medicament is calculated, activity of the reagent agent to test worm is evaluated with this.

 

Table 6 is the toxicity test result of compound drug of the present invention and single medicament to Papillosa

The proportioning of paichongding and cypermethrin is can be seen that 1 from form above:25~25：When in 1 scope, its co-toxicity coefficient to Papillosa is all higher than 120, illustrates that both show as gain effect at mixture in the range of this, especially when both ratios are 1:When 1, gain effect is especially prominent.

 

Efficiency test

When the effect of active compound combinations exceedes the summation of the effect when each reactive compound is administered alone, there is synergistic function.So-called " Colby formula " can be used (referring to S.R. Colby in the predictive role of the particular combination of two kinds of reactive compounds, " Calculating Synergistic and Antagonistic Responses of Herbicide Combinations ", Weeds 1967,15,20-22) it is calculated as below:If

X is when the use of consumption being mg/ha or activity during reactive compound A that concentration is mppm； 

Y is, when the use of consumption being ng/ha or activity during reactive compound B that concentration is nppm, to be expressed as accounting for the percentage of untreated control；

E be when the use of consumption being m and n g/ha or activity during reactive compound A and B that concentration is m and n ppm,

So

If the activity of actual observation（O）More than expection activity（E）, then said composition it is super plus and, i.e., with synergistic effect. 

Following biological test example is to illustrate the present invention.But, the present invention is not limited to these embodiments.

 

Test the controlling experiment of 6 pairs of planthoppers

Solvent:The dimethylformamide of 7 parts by weight

Emulsifying agent:The alkylaryl polyglycol ether of 2 parts by weight

To prepare suitable active agent preparations, the reactive compound of 1 parts by weight is mixed with the solvent and emulsifying agent of the amount, and the dope is diluted with water to required concentration.

It will be handled by the rice leaf that planthopper is seriously infected by the active agent preparations of concentration needed for immersion.

After required time, it is determined that the death rate in terms of %.100% represents that whole planthoppers are killed；0% represents that no planthopper is killed.The death rate of determination is substituted into Colby formula.

In this experiment, for example, the following active agent combinations of the application are compared with the reactive compound being administered alone, the activity that collaboration is improved is shown：

Planthopper is tested

Test the controlling experiment of 7 pairs of tomato trialeurodes vaporariorums

Solvent:The dimethylformamide of 7 parts by weight

Emulsifying agent:The alkylaryl polyglycol ether of 2 parts by weight

To prepare suitable active agent preparations, the reactive compound of 1 parts by weight is mixed with the solvent and emulsifying agent of the amount, and the dope is diluted with water to required concentration.

It will be handled by the tealeaves that trialeurodes vaporariorum seriously infects by the active agent preparations of concentration needed for immersion.

After required time, it is determined that the death rate in terms of %.100% represents that whole trialeurodes vaporariorums are killed；0% represents that no trialeurodes vaporariorum is killed.The death rate of determination is substituted into Colby formula.

In this experiment, for example, the following active agent combinations of the application are compared with the reactive compound being administered alone, the activity that collaboration is improved is shown：

Trialeurodes vaporariorum is tested

Test the controlling experiment of 8 pairs of eggplant aphids

Solvent:The dimethylformamide of 7 parts by weight

Emulsifying agent:The alkylaryl polyglycol ether of 2 parts by weight

To prepare suitable active agent preparations, the reactive compound of 1 parts by weight is mixed with the solvent and emulsifying agent of the amount, and the dope is diluted with water to required concentration.

It will be handled by the eggplant leaf that aphid is seriously infected by the active agent preparations of concentration needed for immersion.

After required time, it is determined that the death rate in terms of %.100% represents that whole aphids are killed；0% represents that no aphid is killed.The death rate of determination is substituted into Colby formula.

In this experiment, for example, the following active agent combinations of the application are compared with the reactive compound being administered alone, the activity that collaboration is improved is shown：

Eggplant aphid is tested

Test the controlling experiment of 9 pairs of Papillosas

Solvent:The dimethylformamide of 7 parts by weight

Emulsifying agent:The alkylaryl polyglycol ether of 2 parts by weight

To prepare suitable active agent preparations, the reactive compound of 1 parts by weight is mixed with the solvent and emulsifying agent of the amount, and the dope is diluted with water to required concentration.

It will be handled by the lychee leaf that stinkbug silk worm seriously infects by the active agent preparations of concentration needed for immersion.

After required time, it is determined that the death rate in terms of %.100% represents that whole stinkbug silk worms are killed；0% represents that no stinkbug silk worm is killed.The death rate of determination is substituted into Colby formula.

In this experiment, for example, the following active agent combinations of the application are compared with the reactive compound being administered alone, the activity that collaboration is improved is shown：

Papillosa is tested

Test the controlling experiment of 10 pairs of cucumber thrips

Solvent:The dimethylformamide of 7 parts by weight

Emulsifying agent:The alkylaryl polyglycol ether of 2 parts by weight

To prepare suitable active agent preparations, the reactive compound of 1 parts by weight is mixed with the solvent and emulsifying agent of the amount, and the dope is diluted with water to required concentration.

It will be handled by the cucumber leaf that thrips is seriously infected by the active agent preparations of concentration needed for immersion.

After required time, it is determined that the death rate in terms of %.100% represents that whole thrips are killed；0% represents that no thrips is killed.The death rate of determination is substituted into Colby formula.

In this experiment, for example, the following active agent combinations of the application are compared with the reactive compound being administered alone, the activity that collaboration is improved is shown：

Cucumber thrips is tested

It can be seen that the present invention by paichongding and cypermethrin by carrying out binary built from above-mentioned embodiment and experiment, the insecticides of acquisition achieve the effect of cooperative gain on insecticidal effect.

Claims (12)

1. a kind of Pesticidal combination containing paichongding and cypermethrin, it is characterised in that：Contain active component paichongding and cypermethrin.

2. a kind of Pesticidal combination containing paichongding and cypermethrin according to claim 1, it is characterised in that：The paichongding and the weight of cypermethrin ratio are 1:25-25:1.

3. a kind of Pesticidal combination containing paichongding and cypermethrin according to claim 1, it is characterised in that：The paichongding and the weight of cypermethrin ratio are 10:1-1:10.

4. a kind of Pesticidal combination containing paichongding and cypermethrin according to claim 1, it is characterised in that：The paichongding and the weight of cypermethrin ratio are 5:1-1:5.

5. a kind of Pesticidal combination containing paichongding and cypermethrin according to claim 1, it is characterised in that：The weight percentage that the paichongding and cypermethrin account for composition altogether is 1%-80%.

6. a kind of Pesticidal combination containing paichongding and cypermethrin according to claim 1, it is characterised in that：The weight percentage that the paichongding and cypermethrin account for composition altogether is 5%-60%.

7. a kind of Pesticidal combination containing paichongding and cypermethrin according to claim 1, it is characterised in that：The weight percentage that the paichongding and cypermethrin account for composition altogether is 10%-50%.

8. a kind of Pesticidal combination containing paichongding and cypermethrin according to claim 1, it is characterised in that：Also include carrier, surfactant and/or other components.

9. the Pesticidal combination of a kind of paichongding according to claim 1 and cypermethrin, it is characterised in that：The formulation is suspending agent, microcapsules, missible oil, suspending agent, water dispersible granules, wettable powder, suspension emulsion, aqueous emulsion, suspension seed-coating agent, granule, dashing agent, drops, microemulsion, microcapsule suspension-suspendinagent agent.

10. the Pesticidal combination of a kind of paichongding and cypermethrin described in claim 1 is used for the purposes for preventing or controlling animal pest.

11. a kind of method for preventing or controlling animal pest, it is characterised in that：One kind is acted on into animal pest and/or its environment containing paichongding and cypermethrin insecticide composition.

12. a kind of method for preventing or controlling animal pest according to claim 11, it is characterised in that：By a kind of animal pest for acting on and being prevented and treated in terms of agricultural, animal health, forest, garden and Relexing device, the protection of Stored Product and health containing paichongding and cypermethrin insecticide composition.