CN103495028B

CN103495028B - Chinese medicine preparation for treating prosopalgia

Info

Publication number: CN103495028B
Application number: CN201310468698.5A
Authority: CN
Inventors: 田雅霞; 刘洪菊; 顾连霞
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-09-25
Filing date: 2013-09-25
Publication date: 2015-05-20
Anticipated expiration: 2033-09-25
Also published as: CN103495028A

Abstract

The invention discloses a Chinese medicine preparation for treating prosopalgia. The traditional Chinese medicine believes that the pathogenesis of the prosopalgia disease is divided into two classes of external infection and internal injury, but most of pains caused by any reason relate to fire pathogen. Thus, the traditional Chinese medicines, such as woolyfruit stylophorum herb, akebiaquinata, Chinese sweetleaf root, saruma root, mosla chinensis maxim, saussurea nigrescens, veined inula root, whorledleaf solomonseal rhizome, multijugous pricklyash root, pungent litse branchlet, viola muehldorfii, trifid sopubia herb and ferrosic oxide, with the effects of expelling wind and cold pathogens, tonifying qi, invigorating circulation of blood, clearing heat, relieving exterior syndrome, calming liver wind, and activating meridians to stop pain, are selected to be decocted into decoction by water. The total effective rate can be up to 97.7% and much better than 79.5% of a control group by a clinical test.

Description

One treats prosopalgic Chinese medicine composition

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to one and treat prosopalgic Chinese medicine preparation.

Background technology

Trigeminal neuralgia is one of Neurology Department commonly encountered diseases, is the severe pain of nervi trigeminus areal area repeated relapsing, transience.Pain each sustainable several seconds, outbreak every day is tens of time to hundreds of times, pain as electric shock sample, the sample that lancinates, burn sample or acupuncture sample.Trigeminal neuralgia is the most common person in all neuralgias, and primary disease is mainly in grows up and old people, and the patient Ke Da 70% ~ 80% of more than 40 years old, women is slightly more than male.Western medicine trigeminal neuralgia generally has good analgesic effect, but often because it has comparatively serious side effect, and patient can not be tolerated, cause adhering to treatment, and fall short of success for lack of final effort.

Summary of the invention

The object of this invention is to provide one and treat prosopalgic Chinese medicine preparation.The traditional Chinese medical science thinks that the cause of disease of primary disease can be divided into the large class of diseases caused by exogenous pathogenic factor, internal injury two, but the pain no matter which kind of reason causes is all many relevant with pathogenic fire.Sayed as in " card is controlled accurate strong ", " prosopodynia all belongs to fire and contains ".Diseases caused by exogenous pathogenic factor caused often by ailment said due to cold or exposure hold under the arm cold, hold fire under the arm, to hold expectorant under the arm assorted and cause a disease; Interior the wounded is many caused by Yangming dryness-heat, feelings will internal injury.Treat primary disease with expelling wind and cold, inrigorating qi and promoting blood circulation, clearing away heat and expelling pathogen in the exterior, suppressing the hyperactive liver to relieve the wind syndrome, removing obstruction in the collateral to relieve pain for principle.

The object of the invention is to be achieved through the following technical solutions, the prosopalgic Chinese medicine preparation of this treatment is made up of the Chinese medicine of following weight portion: Herba Stylophori Lasiocapi 5-10 part, Caulis Akebiae 5-10 part, Radix Symplocoris chinensis 10-20 part, Radix Sarumatis henryi 2-5 part, Herba Moslae Chinensis 10-20 part, Herba saussureae nigrescentis 10-15 part, Radix Inulae Nervosae 30-50 part, Rhizoma Polygonati Verticillati 10-15 part, Radix Zanthoxyli multijugi 20-30 part, Caulis Litseae pungentis 5-15 part, Radix violae delavayi 5-10 part, Herba sopubiae Trifidae 10-15 part, pulvis ferri (ferrosic oxide) 15-25 part.

Preferably, Herba Stylophori Lasiocapi 8 parts, Caulis Akebiae 8 parts, Radix Symplocoris chinensis 15 parts, Radix Sarumatis henryi 3 parts, Herba Moslae Chinensis 15 parts, Herba saussureae nigrescentis 125 parts, Radix Inulae Nervosae 40 parts, Rhizoma Polygonati Verticillati 12 parts, Radix Zanthoxyli multijugi 25 parts, Caulis Litseae pungentis 10 parts, Radix violae delavayi 8 parts, Herba sopubiae Trifidae 12 parts, pulvis ferri (ferrosic oxide) 20 parts.

Above-mentioned Chinese medicine decocting is made decoction by preparation method.

Fang Zhong: Herba Stylophori Lasiocapi's circulation of qi promoting dissipating blood stasis, hemostasis and pain-relieving; Caulis Akebiae clearing away heat and promoting diuresis, blood circulation and channel invigorating; Radix Symplocoris chinensis clearing away heat-damp and promoting diuresis, reduce phlegm preventing the attack (or recurrence) of malaria; Radix Sarumatis henryi regulating QI to relieve pain; Herba Moslae Chinensis is regulated the flow of vital energy, invigorate blood circulation, pain relieving; Herba saussureae nigrescentis expelling wind and removing dampness, heat clearing away of invigorating blood circulation; Grass becomes clever cold-dispelling, the meridian dredging; Rhizoma Polygonati Verticillati suppressing the hyperactive liver to relieve the wind syndrome, yin nourishing easing the affected liver; Radix Zanthoxyli multijugi jiao dispelling cold and analgesia; Caulis Litseae pungentis expelling wind and cold, warming middle-JIAO is regulated the flow of vital energy; Radix violae delavayi, Herba sopubiae Trifidae promoting the flow of QI in the collateral by warming the meridian, removing damp and stopping pain; Pulvis ferri (ferrosic oxide) checking hyperfunction of the liver for relieving convulsion.

Clinical data

This group of physical data patient 88 example, is out-patient, by table of random number, case is divided at random treatment group and each 44 examples of matched group.Treatment group man 20 example, female 24 example; 23 ~ 54 years old age, average 37.1 years old, the course of disease 1 ~ 3 year.Matched group man 19 example, female 25 example; Age is 26 ~ 54 years old, average 37.5 years old, the course of disease 1 ~ 3 year.Two groups of patients compare in age, sex, the course of disease, and no significant difference (P>0.05), has comparability.

Diagnostic criteria (1) is in ictal severe pain, and the persistent period is short, general several seconds to 2 ~ 3mi n.(2) pain is confined to, in nervi trigeminus areal area, not surmount trifacial distribution.(3) facial area has trigger point.(4) the no positive finding of intermission neurologic check.

Therapeutic Method treatment group takes Chinese medicine preparation of the present invention, take Herba Stylophori Lasiocapi 8g, Caulis Akebiae 8g, Radix Symplocoris chinensis 15g, Radix Sarumatis henryi 3g, Herba Moslae Chinensis 15g, Herba saussureae nigrescentis 125g, Radix Inulae Nervosae 40g, Rhizoma Polygonati Verticillati 12g, Radix Zanthoxyli multijugi 25g, Caulis Litseae pungentis 10g, Radix violae delavayi 8g, Herba sopubiae Trifidae 12g, pulvis ferri (ferrosic oxide) 20g, decocting becomes decoction, potion, divided and sooner or later took for 2 times every day; Matched group takes carbamazepine 100 ~ 200mg/ day, then increases 100mg every day, and increase to gradually and maintain 400 ~ 800mg/ day, maximum is no more than 1600mg/ day.A course for the treatment of on the seven, two groups all serve on two courses for the treatment of.

Criterion of therapeutical effect is cured: panic attacks disappears; Effective: pain relief when attack times reduces or shows effect; Invalid: symptom has no and takes a turn for the better or increase the weight of.

Therapeutic outcome two groups treats comparitive study after two courses for the treatment of, and treatment group 44 example, wherein cures 22 examples (50%), effective 21 examples (47.7%), invalid 1 example (2.3%), total effective rate 97.7%; Matched group 44 example, wherein cures 15 examples (34%), effective 20 examples (45.5%), no effect 9 (20.5%), total effective rate 79.5%.Two groups are compared, and treatment group cure rate, total effective rate are obviously better than matched group, have comparability (P<0.05).

There is no obvious adverse reaction after treatment group drug administration, after matched group drug administration, have 15 routine patients' existence untoward reaction in various degree, as blurred vision or diplopia, diarrhoea, unrelenting headache, drowsiness, unable etc.

Detailed description of the invention

Embodiment one: take Herba Stylophori Lasiocapi 8g, Caulis Akebiae 8g, Radix Symplocoris chinensis 15g, Radix Sarumatis henryi 3g, Herba Moslae Chinensis 15g, Herba saussureae nigrescentis 125g, Radix Inulae Nervosae 40g, Rhizoma Polygonati Verticillati 12g, Radix Zanthoxyli multijugi 25g, Caulis Litseae pungentis 10g, Radix violae delavayi 8g, Herba sopubiae Trifidae 12g, pulvis ferri (ferrosic oxide) 20g, makes decoction by above-mentioned Chinese medicine decocting.

Embodiment two: take Herba Stylophori Lasiocapi 5g, Caulis Akebiae 10g, Radix Symplocoris chinensis 10g, Radix Sarumatis henryi 5g, Herba Moslae Chinensis 10g, Herba saussureae nigrescentis 15g, Radix Inulae Nervosae 30g, Rhizoma Polygonati Verticillati 15g, Radix Zanthoxyli multijugi 20g, Caulis Litseae pungentis 15g, Radix violae delavayi 5g, Herba sopubiae Trifidae 10g, pulvis ferri (ferrosic oxide) 25g, makes decoction by above-mentioned Chinese medicine decocting.

Embodiment three: take Herba Stylophori Lasiocapi 10g, Caulis Akebiae 5g, Radix Symplocoris chinensis 20g, Radix Sarumatis henryi 2g, Herba Moslae Chinensis 20g, Herba saussureae nigrescentis 10g, Radix Inulae Nervosae 50g, Rhizoma Polygonati Verticillati 10g, Radix Zanthoxyli multijugi 30g, Caulis Litseae pungentis 5g, Radix violae delavayi 10g, Herba sopubiae Trifidae 15g, pulvis ferri (ferrosic oxide) 15g, makes decoction by above-mentioned Chinese medicine decocting.

Claims

1. treat a prosopalgic Chinese medicine composition, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Herba Stylophori Lasiocapi 5-10 part, Caulis Akebiae 5-10 part, Radix Symplocoris chinensis 10-20 part, Radix Sarumatis henryi 2-5 part, Herba Moslae Chinensis 10-20 part, Herba saussureae nigrescentis 10-15 part, Radix Inulae Nervosae 30-50 part, Rhizoma Polygonati Verticillati 10-15 part, Radix Zanthoxyli multijugi 20-30 part, Caulis Litseae pungentis 5-15 part, Radix violae delavayi 5-10 part, Herba sopubiae Trifidae 10-15 part, pulvis ferri (ferrosic oxide) 15-25 part.

2. one according to claim 1 treats prosopalgic Chinese medicine composition, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Herba Stylophori Lasiocapi 8 parts, Caulis Akebiae 8 parts, Radix Symplocoris chinensis 15 parts, Radix Sarumatis henryi 3 parts, Herba Moslae Chinensis 15 parts, Herba saussureae nigrescentis 125 parts, Radix Inulae Nervosae 40 parts, Rhizoma Polygonati Verticillati 12 parts, Radix Zanthoxyli multijugi 25 parts, Caulis Litseae pungentis 10 parts, Radix violae delavayi 8 parts, Herba sopubiae Trifidae 12 parts, pulvis ferri (ferrosic oxide) 20 parts.