CN103446288A - Health food for prevention and treatment of diabetes - Google Patents
Health food for prevention and treatment of diabetes Download PDFInfo
- Publication number
- CN103446288A CN103446288A CN2012101768692A CN201210176869A CN103446288A CN 103446288 A CN103446288 A CN 103446288A CN 2012101768692 A CN2012101768692 A CN 2012101768692A CN 201210176869 A CN201210176869 A CN 201210176869A CN 103446288 A CN103446288 A CN 103446288A
- Authority
- CN
- China
- Prior art keywords
- parts
- health food
- weight portion
- content
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a health food for prevention and treatment of diabetes. The health food comprises main components of epimeddium, ginkgo biloba, Radix Astragali, licorice, honeysuckle flower, cape jasmine, mulberry leaf and root of kudzu vine. The dosage forms of the health food comprise a capsule, a tablet, a particulate agent, an oral liquid, a powder and a tea bag. The health food has good preventing and therapeutic effects on various types of diabetes.
Description
Technical field
The present invention relates to a kind of health food for prevention and treatment diabetes.Take specifically the health food that Herba Epimedii, Folium Ginkgo, the Radix Astragali, Radix Glycyrrhizae, Flos Lonicerae, Fructus Gardeniae, Folium Mori, raw pueraria powder be component.
Background technology
Diabetes (diabetes) are to act on body by various virulence factors such as inherited genetic factors, immunologic function disorder, infected by microbes and toxin thereof, free radical toxin, Nervous and Mental Factors to cause hypoinsulinism, insulin resistant (Insulin Resistance, and a series of metabolism disorder syndromes such as the sugar caused, protein, fat, power and water Xie Zhi IR) etc., take hyperglycemia clinically as main feature, the performance such as polyuria, polydipsia, polyphagia can appear in model case, become thin, i.e. " three-many-one-little " symptom.
In recent years, the research of relevant natural materials hypoglycemic activity deepens continuously, and has found multiple curative effect really from natural materials and significant active component, for preventing and treating diabetes and verify new direction.
Summary of the invention
It is primary raw material that Herba Epimedii, Folium Ginkgo, the Radix Astragali, Radix Glycyrrhizae, Flos Lonicerae, Fructus Gardeniae, Folium Mori, Radix Puerariae are take in the present invention, try hard to from the angle of health care, provide a kind of health food that blood sugar lowering is intended to prevention and treatment diabetes that has, the raw material components that health food of the present invention contains following weight parts:
The optimum ratio of health food of the present invention is the raw material that contains following weight parts:
Above-mentioned raw materials is used as medicine with former powder, and former powder can adopt commercially available product, or buys medical material and pulverized, sieve and obtain.
Above-mentioned raw materials except adopting former powder, one or more or all can substitute with extract separately the commercially available extract of above-mentioned raw materials for example.When Herba Epimedii is used extract, weight portion is 0.2-2, wherein Icariin content >=20%; When Folium Ginkgo is used extract, weight portion is 0.2-2, wherein Ginkgo total flavones content >=20%; When the Radix Astragali is used extract, weight portion is 0.5-4, wherein astragalus polysaccharides content >=20%; When Radix Glycyrrhizae is used extract, weight portion is 0.5-3, wherein glycyrrhizic acid content >=2%; When Flos Lonicerae is used extract, weight portion is 0.5-3, its Content of Chlorogenic Acid >=1.5%; When Fructus Gardeniae is used extract, weight portion is 1-3, wherein Determination of Gardenoside Content >=3%; When Folium Mori are used extract, weight portion is 1-3, wherein flavones in mulberry leaves content >=1%; When Radix Puerariae is used extract, weight portion is 0.1-1, wherein Radix Puerariae flavone content >=30%.
In the health food of the invention described above, can also contain edible or pharmaceutic adjuvant.
The above-mentioned edible or pharmaceutic adjuvant that can add comprises: diluent, suspending agent, antioxidant, emulsifying agent, disintegrating agent, adhesive and antiseptic.
Above-mentioned diluent comprises vegetable oil, molecular weight polyethylene glycol 200-6000, the third two liquor-saturated, glycerol, sorbitol, D-xylitol, calcium glycerophosphate, polyvinylpolypyrrolidone, inositol, maltose alcohol, lactobionic acid, cyclodextrin, lactose, calcium oxide, cellulose, glucose, carboxymethyl cellulose, polyvinyl butyral resin etc., and one or more in mineral oil.
Above-mentioned antioxidant comprises one or more in dibenzylatiooluene (BHT), butylated hydroxyarisol (BHA), propyl gallate, tert-butyl hydroquinone (TBHQ), malic acid, glutathion, D-xylose, glycine, a-tocopherol, a-tocopheryl acetate, sodium sulfite, inositol, ascorbic acid, phytic acid, sodium ascorbate, lecithin, hydroquinone, xylitol, succinic acid, tea polyphenols.
Above-mentioned suspending agent comprises one or more in Cera Flava, xanthan gum, arabic gum, casein, methylcellulose, Carboxymethyl cellulose sodium, carbomer, polyvinyl alcohol, hydroxyethyl-cellulose, sodium alginate, chitin, chitose, hydroxypropyl emthylcellulose, ethyl cellulose, agar, hydroxyethylmethyl-cellulose, hyprolose.
Mentioned emulsifier comprises one or more in ethylhydroxyethylcellulose, methylcellulose, glyceryl monostearate, hydroxylated lecithin, the single glycerol vinegar of acetylation, orthoformic acid, casein, ethylene glycol monostearate, diacetyl monoglyceride, acetic acid-fatty acid glycerine vinegar, Emulsifier LM-102, propylene glycol alginate.
Above-mentioned binding agent comprises methylcellulose (MC), polyvinylpyrrolidone (PVP), hydroxypropyl cellulose (HPC), hydroxypropyl emthylcellulose (HPMC), polyvinyl alcohol (PVA), Cellulose Acetate Phthalate (CAP), PVP K30, ethyl cellulose (EC), microcrystalline Cellulose (CC), acrylic resin, Semen Maydis unit, Resina persicae, maltose alcohol, poloxamer; A kind of or youngster's kind in sodium alginate, liquid glucose, Nulomoline, the acid of sucrose mono laurate.
Above-mentioned disintegrating agent comprises one or more in silica sol, Magnesiumaluminumsilicate, magnesium stearate, pregelatinized starch, cross-linking sodium carboxymethyl cellulose.
Foregoing preservatives comprises one or more in sorbic acid, Sodium Methyl Hydroxybenzoate, benzoic acid, sorbic acid methyl ester, methyl parahydroxybenzoate, P-hydroxybenzoic acid phenyl ester, butyl p-hydroxybenzoate calcium, Oleum Caryophylli, benzyl alcohol, P-hydroxybenzoic acid the third phenol sodium.
The health food of prevention of the present invention and treatment diabetes, upper on the basis of mentioned component, the former powder of raw material or extract directly or are again added to suitable edible or pharmaceutic adjuvant, and prepare according to conventional preparation technique, can make capsule, tablet, granule, oral liquid, powder, teabag etc.
The specific embodiment
The preparation of embodiment 1. tablets
Get Herba Epimedii extract (containing Icariin 20%) 5g, Folium Ginkgo 16g, Radix Astragali 320g, Radix Glycyrrhizae 120g, Flos Lonicerae 200g, Fructus Gardeniae 160g, Folium Mori 140g, Radix Puerariae 240g, lactose 100g, sorbitol 80g, microcrystalline Cellulose 10g, polyvidone 10g, Magnesiumaluminumsilicate 1g, make 1000.
The preparation of embodiment 2. powders
Get Herba Epimedii 180g, Folium Ginkgo 16g, Radix Astragali 320g, Radix Glycyrrhizae 120g, Flos Lonicerae 200g, Fructus Gardeniae 160g, Folium Mori 140g, Radix Puerariae 240g, pulverize, and crosses 100 mesh sieves, is packed as 250 bags, obtains.
The preparation of embodiment 3. capsules
Get Herba Epimedii 180g, Folium Ginkgo 16g, Radix Astragali 320g, Radix Glycyrrhizae 120g, Flos Lonicerae 200g, Fructus Gardeniae 160g, Folium Mori 140g, Radix Puerariae 240g, pulverize, and crosses 100 mesh sieves, encapsulated, makes 1000, obtains.
Embodiment 4. effect of lowering blood sugar experiments
(1) the diabetic mice model is set up: male ICR kind mice, and after fasting 24h, lumbar injection alloxan normal saline solution, dosage is 180mg/kg.By mice fasting 4h, cut tail after 7d, by blood glucose meter, survey the mice fasting glucose, the mice of choosing blood glucose value 10 ~ 25mmol/L is the hyperglycemia model experimental group, and carries out the stratified random grouping by blood sugar level.
(2) dosage and grouping: establish high, medium and low dosage group and matched group, 10 every group, successive administration 28 days, reduced the fasting glucose experiment.
Table 1 pair alloxan causes the effect that diabetic mice reduces fasting glucose
Compare * P<0.05 with the experiment contrast class value
(3) result and conclusion: relatively, blood glucose has obvious reduction (P<0.05) for high, middle dosage group and experiment contrast group.Show that health food of the present invention has the effect that reduces tissue of experimental diabetic mice blood glucose.
Claims (6)
1. a health food that prevents and treat diabetes, is characterized in that the former powder of the raw material that contains following weight parts: 3～15 parts of Herba Epimedii, 5～10 parts of Folium Ginkgos, 9～30 parts of the Radixs Astragali, 2～9 parts, Radix Glycyrrhizae, 6～15 parts of Flos Loniceraes, 5～10 parts of Fructus Gardeniaes, 5～9 parts, Folium Mori, Radix Puerariae 9～15.
2. the health food of a kind of prevention as claimed in claim 1 and treatment diabetes, is characterized in that being the former powder of the raw material that contains following weight parts: 9 parts of Herba Epimedii, 8 parts of Folium Ginkgos, 16 parts of the Radixs Astragali, 6 parts, Radix Glycyrrhizae, 10 parts of Flos Loniceraes, 8 parts of Fructus Gardeniaes, 7 parts, Folium Mori, 12 parts of Radix Puerariaes.
3. the health food of a kind of prevention as described as claim 1 ~ 2 and treatment diabetes, is characterized in that also containing edible or pharmaceutic adjuvant.
4. the health food of prevention as described as claim 1 ~ 3 and treatment diabetes, is characterized in that one or more in the former powder of raw material of Herba Epimedii, Folium Ginkgo, the Radix Astragali, Radix Glycyrrhizae, Flos Lonicerae, Fructus Gardeniae, Folium Mori, Radix Puerariae or all can substitute with extract separately.
5. the health food of prevention as described as claim 1 ~ 4 and treatment diabetes, is characterized in that weight portion is 0.2-2 when Herba Epimedii is used extract, wherein Icariin content >=20%; When Folium Ginkgo is used extract, weight portion is 0.2-2, wherein Ginkgo total flavones content >=20%; When the Radix Astragali is used extract, weight portion is 0.5-4, wherein astragalus polysaccharides content >=20%; When Radix Glycyrrhizae is used extract, weight portion is 0.5-3, wherein glycyrrhizic acid content >=2%; When Flos Lonicerae is used extract, weight portion is 0.5-3, its Content of Chlorogenic Acid >=1.5%; When Fructus Gardeniae is used extract, weight portion is 1-3, wherein Determination of Gardenoside Content >=3%; When Folium Mori are used extract, weight portion is 1-3, wherein flavones in mulberry leaves content >=1%; When Radix Puerariae is used extract, weight portion is 0.1-1, wherein Radix Puerariae flavone content >=30%.
6. as the preparation method of any one described health food of claim 1 ~ 5, it is characterized in that the former powder of raw material or extract, directly or again add edible or pharmaceutic adjuvant, be prepared into capsule, tablet, granule, oral liquid, powder, teabag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101768692A CN103446288A (en) | 2012-05-31 | 2012-05-31 | Health food for prevention and treatment of diabetes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012101768692A CN103446288A (en) | 2012-05-31 | 2012-05-31 | Health food for prevention and treatment of diabetes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103446288A true CN103446288A (en) | 2013-12-18 |
Family
ID=49729401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012101768692A Pending CN103446288A (en) | 2012-05-31 | 2012-05-31 | Health food for prevention and treatment of diabetes |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103446288A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511476A (en) * | 2016-12-21 | 2017-03-22 | 南阳师范学院 | Blood pressure, lipid and glucose reducing oral liquid for elderly |
| JP7545204B2 (en) | 2019-12-06 | 2024-09-04 | 小林製薬株式会社 | tablet |
-
2012
- 2012-05-31 CN CN2012101768692A patent/CN103446288A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511476A (en) * | 2016-12-21 | 2017-03-22 | 南阳师范学院 | Blood pressure, lipid and glucose reducing oral liquid for elderly |
| JP7545204B2 (en) | 2019-12-06 | 2024-09-04 | 小林製薬株式会社 | tablet |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102273621B (en) | A kind of food of prevention and therapy diabetes or health food | |
| CN103417683A (en) | Health food capable of reducing blood sugar | |
| CN102178753B (en) | Medicinal preparation with effects of clearing heat, purging intense heat, detoxifying, eliminating blood stasis, cooling blood and stopping bleeding | |
| CN102813765A (en) | Method for preparing Zhixinkang preparation | |
| CN104983844A (en) | Edible composition formula with mucous-membrane restoring function and preparation process of preparation thereof | |
| CN103446288A (en) | Health food for prevention and treatment of diabetes | |
| CN107007614A (en) | The medical usage of cycloastragenol | |
| CN101564424B (en) | Common lamiophlomis root chewable tablet and preparation thereof | |
| CN101628053A (en) | Chinese herbal medicament used to treat painful swollen gum caused by intense stomach fire | |
| CN107854671A (en) | A Na series anaesthetic intragastric floating sustained-release preparations and preparation method thereof | |
| CN101683461B (en) | Application of a traditional Chinese medicine composition in preparation of medicament for inhibiting oxidation damage | |
| CN103083622A (en) | Compound preparation | |
| CN1403130A (en) | Cough-relieving bagged tea and its prepn | |
| CN102247515B (en) | Traditional Chinese medicine compound preparation used for treating diabetic nephropathy, and preparation method thereof | |
| CN106943390B (en) | Application of the Strychnos nux-vomica aglycon in preparation prevention or treatment antiarrhythmic medicament | |
| CN106063794A (en) | Phillyrin, its derivant, phillyrin and phillygenol compositions in preparation prevention or/and application in treatment liver injury medicament | |
| CN101491628A (en) | Lycium-rehmannia preparation and preparation method thereof | |
| CN105560984B (en) | Traditional Chinese medicine composition capable of boosting qi and invigorating spleen | |
| CN105288107B (en) | Compound hippophae rhamnoides clearing composition and preparation method thereof | |
| CN115025163B (en) | Double golden camellia traditional Chinese medicine composition and preparation method and application thereof | |
| CN1785248B (en) | Effervescent of compounding medicines | |
| CN108477372A (en) | A kind of Inonotus obliquus pressed candy of energy anticancer reducing pressure and sugar anti-aging tranquilizing effect | |
| CN103099905A (en) | Spleen deficiency and dampness abundance type acne treatment drug | |
| CN102210808A (en) | Method for preparing Chinese medicinal composition for treating infantile pharyngitis | |
| CN103127231A (en) | Chinese medicine for diabetes treatment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20131218 |