CN103400528A - Teaching aid of insulin structure model - Google Patents

Teaching aid of insulin structure model Download PDF

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Publication number
CN103400528A
CN103400528A CN2013103342082A CN201310334208A CN103400528A CN 103400528 A CN103400528 A CN 103400528A CN 2013103342082 A CN2013103342082 A CN 2013103342082A CN 201310334208 A CN201310334208 A CN 201310334208A CN 103400528 A CN103400528 A CN 103400528A
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CN
China
Prior art keywords
pearl
string
beading
connecting portion
pearl string
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Pending
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CN2013103342082A
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Chinese (zh)
Inventor
郑小坚
朱越雄
贡成良
曹广力
薛仁宇
潘中华
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Suzhou University
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Suzhou University
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Publication date
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Priority to CN2013103342082A priority Critical patent/CN103400528A/en
Publication of CN103400528A publication Critical patent/CN103400528A/en
Pending legal-status Critical Current

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention discloses a teaching aid of an insulin structure model. The teaching aid of the insulin structure model comprises a first bead string, a second bead string and a third bead string, wherein the second bead string and the third bead string are connected with the first bead string through a connecting part respectively; and connecting strings are arranged between the second bead string and the third bead string. The teaching aid of the insulin structure model is simple in structure and is of a detachable structure; and therefore, not only can the structure characteristics of insulin be displayed vividly, but also the memory of a user can be deepened, which is beneficial to teaching.

Description

A kind of insulin structure model teaching aid
Technical field
The present invention relates to the teaching aid field, relate in particular to a kind of insulin structure model teaching aid.
Background technology
Insulin (Insulin) is to be subjected to the stimulation of endogenous or exogenous material (as glucose, lactose, ribose, arginine, hyperglycemic factor etc.) and a kind of proteohormone of secreting by pancreas islet B cell.
Insulin can promote picked-up and the utilization of body tissue's cell to glucose, and suppresses decomposition and the gluconeogenesis of glycogen, and therefore, pancreas islet have the effect that reduces blood sugar.Insulin can promote the synthetic of fat and store, and the blood free fatty acid is reduced, and suppresses simultaneously the decomposition oxidation of fat.Insulin deficit can cause fat metabolic disturbance, and depot fat reduces, and decomposes and strengthens, and blood fat raises, and of a specified duration can cause artery sclerosis, and then causes the serious illness of cardiovascular and cerebrovascular; Meanwhile, insulin deficit can cause body fat to decompose reinforcement, generates a large amount of ketoboidies, ketoacidosis occurs.Insulin promotes synthetic to amino acid whose picked-up and protein of cell on the one hand, the decomposition of Profilin matter on the one hand, thereby be conducive to growth.The protein stimulatory matter synthesis of adenohypophysis growth hormone, must have the existence of insulin just can show.Therefore, for growth, insulin is also one of indispensable hormone.Insulin can promote potassium ion and magnesium ion to pass cell membrane to enter in cell; Can promote the synthetic of DNA (deoxyribonucleic acid) (DNA), RNA (ribonucleic acid) (RNA) and atriphos (ATP).
Therefore, the research of insulin is particularly important with utilization.Because insulin belongs to the molecule rank, need to use electron microscope observation, bring inconvenience in teaching field, teacher generally uses picture when explanation insulin, yet picture lacks vividness, can not well cause student's interest, can not effectively deepen student's memory.
Summary of the invention
The insulin structure model teaching aid that the purpose of this invention is to provide a kind of simple in structure, removable 3-D solid structure.
to achieve the above object of the invention, the technical solution used in the present invention is: a kind of insulin structure model teaching aid, comprise the first pearl string, the second pearl string, the 3rd pearl string, described the second pearl string, the 3rd pearl ganged up connecting portion and described the first pearl series winding connects, be provided with 31 beading on described the first pearl string, be provided with 21 beading on described the second pearl string, be provided with 30 beading on described the 3rd pearl string, be provided with and be connected string between the 6th beading of an end counting that described the second pearl series winding connects connecting portion and the 11st beading, be provided with and be connected string between the end that the 7th beading of an end counting that described the second pearl series winding connects connecting portion and the 3rd pearl series winding connect connecting portion is counted the 24th, be provided with and be connected string between the end that the 20th beading of an end counting that described the second pearl series winding connects connecting portion and the 3rd pearl series winding connect connecting portion is counted the 12nd.
In technique scheme, the first pearl string, the second pearl string, the 3rd pearl string are all that magnetic material is made, and each pearl string has certain pliability, arbitrarily bending.
Preferred technical scheme, described connecting portion is composed of a fixed connection by two beading.
Further technical scheme, described connecting portion two ends are provided with jack.
Further technical scheme, described connecting portion two ends are provided with magnet.
Preferred technical scheme, described connection string comprise center-pole and are located in two beading on described center-pole.
Further technical scheme, described center-pole two ends are provided with magnet.
Further technical scheme, described the second pearl series winding connect on the 12nd, the 24th beading of the 6th, the 7th, the 11st, the 20th beading of an end counting of connecting portion and the end counting that the 3rd pearl series winding connects connecting portion and are provided with the connecting hole that matches with described center-pole.
Because technique scheme is used, the present invention compared with prior art has following advantages:
The present invention is 3-D solid structure, can show very visually the structural form of insulin, and is disassembly and assembly structure, can improve student's manipulative ability and can also deepen the memory of student to insulin.
Description of drawings
Fig. 1 is structural representation of the present invention;
Fig. 2 is embodiment one broken away view.
Wherein: 1, the first pearl string; 2, the second pearl string; 3, the 3rd pearl string; 4, connecting portion; 5, connect string.
Embodiment
The invention will be further described below in conjunction with drawings and Examples:
Embodiment one:
as shown in Figure 1-2, a kind of insulin structure model teaching aid, it comprises the first pearl string 1, the second pearl string 2, the 3rd pearl string 3, the second pearl string 2, the 3rd pearl string 3 is connected with the first pearl string 1 by connecting portion 4, be provided with 31 beading on the first pearl string 1, be provided with 21 beading on the second pearl string 2, be provided with 30 beading on the 3rd pearl string 3, be provided with to be connected between the 6th beading of an end counting that the second pearl string 2 connects connecting portions 4 and the 11st beading and go here and there 5, the 7th beading of an end counting that the second pearl string 2 connects connecting portions 4 are connected with the 3rd pearl string 3 and are provided with connection between the 24th of the end counting of connecting portion 4 and go here and there 5, the 20th beading of an end counting that the second pearl string 2 connects connecting portions 4 are connected with the 3rd pearl string 3 and are provided with connection between the 12nd of the end counting of connecting portion 4 and go here and there 5.
Connecting portion 4 is composed of a fixed connection by two beading.
Connecting portion 4 two ends are provided with jack.
Connecting string 5 comprises again center-pole and is located in two beading on center-pole.
The second pearl string 2 connects on the 12nd, the 24th beading of the 6th, the 7th, the 11st, the 20th beading of an end counting of connecting portions 4 and the end counting that the 3rd pearl string 3 connects connecting portions 4 and is provided with the connecting hole that matches with center-pole.
In use, the first pearl string 1 represents the C peptide in proinsulin; The second pearl string 2 represents the A chain; The 3rd pearl string 3 represents the B chain; Connecting portion 4 represents proinsulin hydrolytic cleavage part, is respectively amino acid K, R and amino acid R, R; Connect string 5 and represent disulfide bond.With above-mentioned all component combinations together, represent 86 peptide proinsulin; The second pearl string 2, the 3rd pearl string 3, connection string 5 are fitted together the insulin that representative has physiological function.
It is well-regulated arranging due to the amino acid of insulin, can stick the amino acid title on each parts.Stick K, R on the first pearl string 1 and connecting portion 4 that the second pearl string 2 is connected; The first pearl string 1 starts to stick successively Q, L, S, G, E, L, A, L, P, Q, L, S, G, A, G, P, G, G, G, L, E, V, Q, G, V, Q, L, D, E, A, E from Fig. 1 left side connecting portion 4; The second pearl string 2 starts to stick successively G, I, V, E, Q, C, C, T, S, I, C, S, L, Y, Q, L, E, N, Y, C, N from connecting portion 4; Stick R, R on the first pearl string 1 and connecting portion 4 that the 3rd pearl string 3 is connected; The 3rd pearl string 3 starts to stick successively T, K, P, T, Y, F, F, G, R, E, G, C, V, L, Y, L, A, E, V, L, H, S, G, C, L, H, Q, N, V, F from connecting portion 4; Connect on string 5 can stick S, S represents sulphur.
Embodiment two:
as shown in Figure 1, a kind of insulin structure model teaching aid, it comprises the first pearl string 1, the second pearl string 2, the 3rd pearl string 3, the second pearl string 2, the 3rd pearl string 3 is connected with the first pearl string 1 by connecting portion 4, be provided with 31 beading on the first pearl string 1, be provided with 21 beading on the second pearl string 2, be provided with 30 beading on the 3rd pearl string 3, be provided with to be connected between the 6th beading of an end counting that the second pearl string 2 connects connecting portions 4 and the 11st beading and go here and there 5, the 7th beading of an end counting that the second pearl string 2 connects connecting portions 4 are connected with the 3rd pearl string 3 and are provided with connection between the 24th of the end counting of connecting portion 4 and go here and there 5, the 20th beading of an end counting that the second pearl string 2 connects connecting portions 4 are connected with the 3rd pearl string 3 and are provided with connection between the 12nd of the end counting of connecting portion 4 and go here and there 5.
The first pearl string 1, the second pearl string 2, the 3rd pearl string 3 are all that magnetic material is made, and each pearl string has certain pliability, arbitrarily bending.
Connecting portion 4 is composed of a fixed connection by two beading.
Connecting portion 4 two ends are provided with magnet.
Connecting string 5 comprises again center-pole and is located in two beading on center-pole.
The center-pole two ends are provided with magnet.
In use, the first pearl string 1 represents the C peptide in proinsulin; The second pearl string 2 represents the A chain; The 3rd pearl string 3 represents the B chain; Connecting portion 4 represents proinsulin hydrolytic cleavage part, is respectively amino acid K, R and amino acid R, R; Connect string 5 and represent disulfide bond.With above-mentioned all component combinations together, represent 86 peptide proinsulin; The second pearl string 2, the 3rd pearl string 3, connection string 5 are fitted together the insulin that representative has physiological function.
It is well-regulated arranging due to the amino acid of insulin, can stick the amino acid title on each parts.Stick K, R on the first pearl string 1 and connecting portion 4 that the second pearl string 2 is connected; The first pearl string 1 starts to stick successively Q, L, S, G, E, L, A, L, P, Q, L, S, G, A, G, P, G, G, G, L, E, V, Q, G, V, Q, L, D, E, A, E from Fig. 1 left side connecting portion 4; The second pearl string 2 starts to stick successively G, I, V, E, Q, C, C, T, S, I, C, S, L, Y, Q, L, E, N, Y, C, N from connecting portion 4; Stick R, R on the first pearl string 1 and connecting portion 4 that the 3rd pearl string 3 is connected; The 3rd pearl string 3 starts to stick successively T, K, P, T, Y, F, F, G, R, E, G, C, V, L, Y, L, A, E, V, L, H, S, G, C, L, H, Q, N, V, F from connecting portion 4; Connect on string 5 can stick S, S represents sulphur.

Claims (7)

1. insulin structure model teaching aid, it is characterized in that: it comprises the first pearl string, the second pearl string, the 3rd pearl string, described the second pearl string, the 3rd pearl ganged up connecting portion and described the first pearl series winding connects, be provided with 31 beading on described the first pearl string, be provided with 21 beading on described the second pearl string, be provided with 30 beading on described the 3rd pearl string, be provided with and be connected string between the 6th beading of an end counting that described the second pearl series winding connects connecting portion and the 11st beading, be provided with and be connected string between the end that the 7th beading of an end counting that described the second pearl series winding connects connecting portion and the 3rd pearl series winding connect connecting portion is counted the 24th, be provided with and be connected string between the end that the 20th beading of an end counting that described the second pearl series winding connects connecting portion and the 3rd pearl series winding connect connecting portion is counted the 12nd.
2. a kind of insulin structure model teaching aid according to claim 1, it is characterized in that: described connecting portion is composed of a fixed connection by two beading.
3. a kind of insulin structure model teaching aid according to claim 1 is characterized in that: described connection string comprises again center-pole and is located in two beading on described center-pole.
4. a kind of insulin structure model teaching aid according to claim 2, it is characterized in that: described connecting portion two ends are provided with jack.
5. a kind of insulin structure model teaching aid according to claim 2, it is characterized in that: described connecting portion two ends are provided with magnet.
6. according to claim 1 or 3 described a kind of insulin structure model teaching aids is characterized in that: described the second pearl series winding connects on the 12nd, the 24th beading of the 6th, the 7th, the 11st, the 20th beading of an end counting of connecting portion and the end counting that the 3rd pearl series winding connects connecting portion and is provided with connecting hole.
7. a kind of insulin structure model teaching aid according to claim 3, it is characterized in that: described center-pole two ends are provided with magnet.
CN2013103342082A 2013-08-02 2013-08-02 Teaching aid of insulin structure model Pending CN103400528A (en)

Priority Applications (1)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2044091U (en) * 1989-01-17 1989-09-06 马泽红 Body blood circulating system dynamics teaching aid
RU2144698C1 (en) * 1996-03-14 2000-01-20 Крашенюк Альберт Иванович Method of modelling medicinal leech effect on stimulation of nervous fiver growth in cultured tissue
CN201845489U (en) * 2010-11-18 2011-05-25 王肇颖 Universal structure model teaching aid for biochemistry
CN103198744A (en) * 2013-04-28 2013-07-10 苏州大学 Gram positive bacteria cell wall model teaching aid
CN203456002U (en) * 2013-08-02 2014-02-26 苏州大学 Insulin composition model teaching tool

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2044091U (en) * 1989-01-17 1989-09-06 马泽红 Body blood circulating system dynamics teaching aid
RU2144698C1 (en) * 1996-03-14 2000-01-20 Крашенюк Альберт Иванович Method of modelling medicinal leech effect on stimulation of nervous fiver growth in cultured tissue
CN201845489U (en) * 2010-11-18 2011-05-25 王肇颖 Universal structure model teaching aid for biochemistry
CN103198744A (en) * 2013-04-28 2013-07-10 苏州大学 Gram positive bacteria cell wall model teaching aid
CN203456002U (en) * 2013-08-02 2014-02-26 苏州大学 Insulin composition model teaching tool

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
项坤三: "《特殊类型糖尿病》", 30 April 2011 *

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Application publication date: 20131120