Background technology
Electro photoluminescence is already with TENS/Tens (Transcutaneous Electrical Nerve
Stimulation-TENS) mode is utilizing.TENS relates to relatively low energy, and typical case
Ground relates to the energy of the transmission between two surface electrodes being applied on skin.This energy with
The beat frequency of 0.1Hz to 200Hz carries out amplitude modulation(PAM), sometimes carries out frequency modulation(PFM).Existing clinical literary composition
Offer the biological cell effect demonstrating these frequencies on health, including contraction of muscle and lax,
Vessel retraction and vasodilation and pain weaken.TENS treatment is limited to the energy that can apply
Amount size is when higher energy, that energy level may become pain and non-treatment, even
It is harmful.TENS treatment is bigger on textura epidermoidea's impact, and does not touch deeper tissue.
Electro photoluminescence has evolved to include, utilizes higher frequency (typically at more than 4000Hz)
As " carrier wave " frequency.At higher frequencies, the resistance of health is less, thus allows higher
Energy transmit in-between the electrodes without produce reaction.At higher frequencies, carrier waveform
Can deeper advance in bodily tissue.
The newer beat frequency between electric stimulation 0.1Hz to 200Hz carrys out amplitude modulation(PAM) two
The carrier frequency waveform of transmission between individual electrode.So, biology can be correlated with by the system of renewal
Beat frequency is transferred to deeper organize.Waveform penetration depth is come really by carrier frequency is increased or decreased
Fixed.For Elbow injury, possible 4000Hz is the most suitable.But, by carrier frequency is increased
To about 8000Hz, treatment beat frequency deeper can be transferred to tissue.Reach in use
And the carrier frequency more than 20,000Hz.This amplitude modulation(PAM) (sometimes for frequency modulation(PFM))
The carrier frequency electro photoluminescence transmitted between two electrodes is referred to as " two pole " electro photoluminescence.
Recently, four electrode electro photoluminescence are had been devised by.In this approach, electrode is typically arranged
Rectangular pattern.One carrier frequency is transmitted between two corner electrodes.Second carrier frequency
Transmit between contrary corner electrode.In the place that carrier frequency intersects, carrier frequency experience phase
Disappear interference and constructive interference.The difference of carrier frequency produces the synthetic waveform of equivalence.Such as, if
4000Hz carrier frequency " intersects " with 4200Hz carrier frequency, then frequency synthesis is 200Hz
Beat frequency (4200Hz subtracts 4000Hz=200Hz).Beat frequency occurs in and each of penetrating body
The depth of the degree of depth equivalence of carrier frequency.The treatment of this form is referred to as " quadrupole " electro photoluminescence.
Two polar stimulations act directly on the tissue of base part, and will down to carrier frequency
The depth penetrated.At waveform, crossing and deeper into tissue depth starts in four polar stimulations.
Have shown that carrier only frequency also can ease the pain.This is widely known by the people in medical circle.
" locally opium effect " is described as the increase of pain position natural opiate concentration.Ah
Sheet is natural " anodyne ", is the method that eases the pain of health self.
" pain gate effect " is described as alleviating the pain letter marching to brain and sending from brain
Number." door " relates to coming from the pain signal of pain position and marches to the passage of brain.Greatly
Signal is explained by brain, and signal returns to pain position.The pain of brain is explained
Determining patient's perception level to pain, this perception level is varied from according to different patients.
Return to a lot of behavior of signal deciding of pain position, including inflammation.In many situations,
Inflammation strengthens and the pain signal returning to brain will be caused to further enhance.This be likely to become pernicious
The reponse system of circulation.Pain medicine relates to the interruption of this feedback cycle.
Summary of the invention
The present invention relates to cause local opium effect and pain gate effect to realize additional and/or association
Same therapeutic value.
One embodiment of the invention relates to the use of electrical stimulation device, and described electrical stimulation device can
The electronic stimulation that transmission two separates simultaneously.Typically, each of electrical stimulation device is controlled
Treat output and be referred to as " passage ".By a passage, any one ordinary electrode is utilized to include suction
Electrode, is applied to pain position by TENS, two pole electro photoluminescence or quadrupole electro photoluminescence.Second leads to
Road is applied and is being connected at the nerve root of backbone pain position.New electrode is used at nerve root,
To shroud area for treatment completely, pain gate effect causes region, carrier only frequency wave regions.
Two passages transmit treatment simultaneously, although being not necessarily this situation.
TENS, two pole electro photoluminescence or quadrupole electro photoluminescence is applied in pain position, thus to known
Pain relief approach produce impact.Utilizing two polar stimulations or the position of four polar stimulations, simultaneously
Obtain local opium effect and pain gate effect.In the position relating to TENS, only obtain
Local, top layer opium effect.In either case, locally opium frequency shows as causing pain
The beat frequency scope of relieving effect is typically 50Hz to 200Hz.In this case, it is necessary to note
The energy that meaning power concentrates on being transferred to pain position limits, so that contraction of muscle is limited
Or do not exist.
One embodiment of the present of invention utilizes new three electrode structures and a kind of two to lead at nerve root
Road electrical stimulation device.
Intactly say, system cause in pain position minimum local opium effect, and
Pain is caused to gate effect by pain signal transmission to the nerve root of brain.Two kinds of effects have
Add and/or synergy.Pain is reduced by the opium concentration increase of pain position.Subtract
Weak signal rows proceeds to brain, gates effect at this together with the pain at related neural root and makes letter
Number further weakened.Weakened pain signal is processed by brain, so that patient's sense
The pain being subject to weakens, and makes the painful response signal being transferred to pain position weaken.
Typically after being shorter than the period of 1 hour (60 minutes), effect reaches maximum.Additionally,
By this new nerve block, pain " numb " position can accept to process further, as simply
Operation.By this, there is medication analgesic structure and system realizes total consumption
Reduce.
Accompanying drawing explanation
Fig. 1: show the back of patient, brain, backbone and rumpbone and spinal cord.
Fig. 2: show nerve root and extend between bone vertebra and the god that extends from rumpbone
Warp, it is connected with body parts.
Fig. 3: show the nerve root leaving backbone and being connected with the elbow of patient to a certain extent
Example.
Fig. 4: show the pure high_frequency sine wave being used in modern electro photoluminescence.
Fig. 5: show beat frequency may for 0.1Hz to 200Hz for cause local opium effect
A pure low-frequency sine (relative to the sine wave shown in Fig. 4).
Fig. 6: show the sine wave of amplitude modulation(PAM) (AM).AM sine wave is the load of Fig. 4
The combination of the beat frequency of ripple frequency and Fig. 5.
Fig. 7: show and typically can use again or disposable electronic pads.Protruding connector includes
Hole or the terminal for the treatment of waveform is inserted and then transmitted to power supply pin.
Fig. 8 A and Fig. 8 B: show typical reusable Venturi tube electrode.Electrode includes making
With screw-type or the buckling connector of the pipe of electrical connection.Pipe transmission compressed air, described compression
Air enters from entrance, through being opened in the aperture on inside sucker, and discharges from outlet.Logical
Cross venturi-effect, air is discharged below sucker, thus produces suction, in order to by electrode
Hold down on skin.Once suction electrode and skin contact, metal in suction cup carrier or lead
Electrical waveform is just carried to skin from pipe by level face.Suction electrode has additional advantage, will
Electrolyte takes surface to and then increases the electric conductivity on surface, and provides nutrition for body fluid.
Fig. 9: show in the way of making TENS or two pole electro photoluminescence transmit between two electrodes
Two electrodes arranged.
Figure 10: show so that two different carrier frequencies are between two electrode groups separated
Transmission and four electrodes arranged for the mode transmitting four polar stimulations that intersect at middle part.
Figure 11: show one embodiment of the present of invention.Show three electrodes.One electrode
Receive the side of carrier only frequency.Two other electrode receives the opposite side of carrier only frequency.Three
Space in dihedral is coated with carrier only frequency.
Figure 12 A and Figure 12 B: show one embodiment of the present of invention.The electrode of the present embodiment
Including three electrode surfaces being incorporated in an electrode body.Three terminals allow three electricity pins to control
Treat electrical stimulation signal and be carried to pad, and enter in patient body in the way of Figure 11 structure.
Figure 13 A and Figure 13 B: show one embodiment of the present of invention.The electrode of the present embodiment
Including three suction electrodes including an electrode body in.Three terminals allow three pipes of charged pin
Carry treatment electro photoluminescence and compressed air (or other gas), and in the way of Figure 11 structure
Enter in patient body.
Figure 14: again illustrate and leave backbone and be connected with the elbow of patient to a certain extent
The example of nerve root.This diagram is convenient reference for last diagram.
Figure 15: show patient body, leaves backbone and the nerve root being connected with the elbow of patient.
In this example of one embodiment of the invention, the elbow pain of patient, it may be possible to " tennis elbow "
Situation.Around facies cubitalis posterior, layout quadrupole electrode is arranged, thus transmits beat frequency at 0.1Hz
And the quadrupole electro photoluminescence between 200Hz.New three plate electrodes of the present invention are placed on and leave ridge
On the nerve root of post, and shrouding in the region of carrier only frequency, nerve root will be from pain
The pain signal of position is carried to brain.
Detailed description of the invention
Fig. 1
Patient body (1000) is shown as line drawing profile, and includes brain (1005), spinal cord
And backbone (1015) and rumpbone (1020) (1010).
Fig. 2
The nerve root (2005) leaving cervical vertebra, thoracic vertebrae, lumbar vertebrae and sacral is shown as covering at Fig. 1
On Suo Shi.
Fig. 3
Neural circuit (3010) is shown as dotted line, nerve root in position (3015) place from
Open backbone and be connected to the pain position supposed, being elbow (3020) in this case.
Fig. 4
Show sine wave (4005), in embodiments of the present invention this sine wave (4005) table
Reveal the carrier frequency of at least 4000Hz.When this sine wave is transferred to patient body, have zero
Net charge, as shown in the waveform walked between a positive electrode and a negative electrode, in zero volt up and down (4010).
Fig. 5
Show sine wave (5005), in embodiments of the present invention this sine wave (5005) table
Show the beat frequency between 0.1Hz and 200Hz.When this sine wave is transferred to patient body, tool
There is zero net electric charge, as shown in the waveform walked between a positive electrode and a negative electrode, upper and lower in zero volt
(5010).This can be the synthesis beat frequency that TENS waveform maybe can represent four polar stimulations.
Fig. 6
Show sine wave (6010), in embodiments of the present invention this sine wave (6010) table
Reveal after carrying out amplitude modulation(PAM) with beat frequency sine wave (6015) between 0.1Hz and 200Hz
The carrier frequency of at least 4000Hz.This is the example of two polar stimulations.When this sine wave is transferred to
During patient body, there is zero net electric charge, as from shown in the waveform walked between positive pole and negative pole,
In zero volt up and down (6005).
Fig. 7
Circular electrode (7005) is conventional design, and the most a diameter of 1.25 inches,
There is the terminal (7010) connected for electricity pin (in this example for the pin of 2mm diameter),
Wherein terminal and electricity pin are the most typical.Electrode (7005) can be by a lot of materials
Material is made.In some cases, electrode (7005) is non-conductive, and with wire by terminal (7010)
It is connected to the conductive surface on the bottom of electrode (7005).Under other circumstances, electrode (7005)
Top conductive, and the lower section of electrode (7005) has the conducting resinl adhering to skin.At it
Under its situation, such as doped with the silicon rubber of a large amount of carbon blacks when, whole electrode (7005)
Conduction.With band or other device, pad is fixed to skin.In some cases, conducting resinl is used
Or even non-distilled water is formed and the electrically connecting completely of skin.
Fig. 8 A and Fig. 8 B
Circular magnetic chuck (8005) is shown as on top having and comprises threaded metallic rod (8010)
Terminal.Compressed air and the signal of telecommunication (8920) are sent into terminal by the pipe of electrical connection.The signal of telecommunication
(8920) conductive plane (8015) it is transferred to.Compressed air enters threaded metallic rod
(8010), entered in sucker (8005) by the hole on conductive plane (8015), and
Discharge from the other end of bar as compressed air stream (8930).By in sucker (8005)
Air is discharged in sucker (8005) by the compressed air that hole enters, and when being applied to such as
During the surface of skin, attracted downwards sucker (8005) by suction.This suction passes through Wen
Tube effect produces.When conductive plane (8015) is attracted to skin contact, by electro photoluminescence
It is transferred to patient.
Sucker (8005) is typically by flexible but fluid-resistant and be biological inert non-conducting material
Make, such as silicon rubber.Threaded shank is as conductive plane (8015), typically by gold
Belong to structure.
Fig. 9
Show two electrodes (9005) and (9010) being configured at TENS or two polar stimulations.
Electro photoluminescence (9015) is transmitted between two electrodes (9005) and (9010).Can be assumed that,
Electrode (9005) contacts with patient skin with (9010).
Figure 10
Showing two electrodes (10,005), the carrier only being illustrated by the broken lines (10,030) is two
Transmit between individual electrode (10,005).Show two extra electrodes (10,010), by reality
The carrier only (10,020) that line represents transmits between two electrodes (10,010).Can be assumed that,
Electrode contacts with patient skin.In the structure shown here, two carrier waves (10,020) and (10,030)
In the local interaction that they intersect, and formed not by constructive interference and destructive interference
Same waveform.In this case, four polar stimulations are transmitted in electrode (10,005) and (10,010).
Figure 11
Show and receive two electrodes (11,005) of an identical electrical connection and receive electrical connection
The 3rd electrode (11,010) of opposite side.Carrier only frequency (11,020) is in electrode (11,005)
And transmit between electrode (11,010).Stimulate and directly do not transmit as shown in arrow, and
It is to occur in triangle.It can be assumed that electrode (11,005) and (11,010) and patient's skin
Skin contacts.
Figure 12 A and Figure 12 B
Show the electrode (12,005) of one embodiment of the invention.Electrode (12,005) comprises
There are three terminals (12,010) for the 2mm hole of electricity pin (common in the art) connection
(12,015).The conductive pad included below (12,020) of electrode (12,005) and (12,030).
Two conductive pads (12,020) receive an identical electrical connection, and the 3rd conductive pad (12,030)
Receive the opposite side of electrical connection.Carrier only frequency is at two conductive pads (12,020) and conductive pad
(12,030) transmit between.Stimulate and formed by conductive pad (12,020) and (12,030)
Transmission in triangle.It can be assumed that conductive pad (12,020) and (12,030) and patient skin
Contact.
Figure 13 A and Figure 13 B
Show the electrode (13,005) of one embodiment of the invention.Electrode (13,005) comprises
Allow three threaded metal terminals that transmission electro photoluminescence and compressed-air actuated pipe are attached
And (13,015) (13,010).Electrode (13,005) lower section comprises suction electrode (13,020)
(13,030).Two suction electrodes (13,020) receive an identical electrical connection, and
3rd suction electrode (13,030) receives the opposite side of electrical connection.Carrier only frequency is two suctions
Transmit between electrode (13,020) and suction electrode (13,030).Stimulate by suction electrode
And transmission in (13,030) triangle of being formed (13,020).It can be assumed that suction electrode
(13,020) and (13,030) contact with patient skin, and when suction electrode (13,020)
When (13,030) are compressed because of the gravitation of venturi-effect, suction electrode (13,020) and
(13,030) conductive plane (8015) is attracted to downwards skin.
Figure 14
Neural circuit (14,010) is shown as dotted line, nerve root in position (14,015) place
Leave backbone, and be connected to the pain position supposed, be elbow (14,020) in this case.
This diagram is consistent with Fig. 3, and is to illustrate for the ease of last diagram reference.
Figure 15
Show one embodiment of the present of invention.Patient body be shown as having brain (15,020) and
Spinal cord and nerve (15,010), nerve is expressed as dotted line and by the pain position on elbow
(15,005) spinal cord with suitable backbone position (15,015) is connected.
As embodiments of the invention, bag is placed in the position leaving backbone in neural (15,010)
Triangular-shaped electrodes (15,030) containing three conductive pads or three suction electrodes.
Put around pain position (15,005) (situation being likely to occur in such as " tennis elbow ")
Put four common electrodes or suction electrode (15,025).
The triangular-shaped electrodes (15,030) of one embodiment of the invention is shrouded by carrier only frequency stimulation
The nerve root of nerve (15,010), thus cause pain to gate effect.Quadrupole around elbow
Electrode structure (15,025) transmission quadrupole electro photoluminescence, thus cause local opium effect.
Two kinds of effects have additional and/or synergy.By increasing pain position (15,005)
The opium concentration at place reduces pain.The signal rows weakened proceeds to brain (15,020), at this together with
Pain at related neural root gates effect and makes signal the most weakened.Brain (15,020) is right
Weakened pain signal processes so that patients' feeling to pain weaken, and
The painful response signal being transferred to pain position (15,005) place is made to weaken.Typically it is being shorter than 1
After the period of hour (60 minutes), effect reaches maximum.Additionally, by this new neural resistance
Stagnant, pain " numb " position can accept to process further, such as simple operation.Logical
Cross this structure showing medication analgesic effect and system to realize the reduction of total consumption.