CN103372262B - Two passage electrical stimulation devices - Google Patents

Two passage electrical stimulation devices Download PDF

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Publication number
CN103372262B
CN103372262B CN201210107368.9A CN201210107368A CN103372262B CN 103372262 B CN103372262 B CN 103372262B CN 201210107368 A CN201210107368 A CN 201210107368A CN 103372262 B CN103372262 B CN 103372262B
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pain
electrode
conductive surface
signal
electro photoluminescence
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CN103372262A (en
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浠诲旦
任嵩
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ANHUI RYZUR AXIOM MEDICAL EQUIPMENT CO LTD
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Beijing Ryzur & Axiom Medical Investment Co Ltd
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Abstract

The present invention relates to a kind of two passage electrical stimulation devices.The electro photoluminescence that its transmission two separates;Wherein: include the electrode for electric nerve retardance, wherein: described electrode be shaped as triangle, and include two conductive surfaces receiving the identical signal of telecommunication and the 3rd conductive surface receiving another signal of telecommunication;Carrier only transmits between conductive surface and the 3rd conductive surface, and electro photoluminescence is transmitted in the triangle that two conductive surfaces and the 3rd conductive surface are formed;Conductive surface and the 3rd conductive surface contact with patient skin;Attenuated signal marches to brain, gates effect at this together with the pain at related neural root and makes signal weaken further.The pain signal weakened is processed by brain so that patients' feeling to pain weaken, and make the painful response signal being transferred to pain position weaken.By new nerve block, pain numbness position can accept to process further, such as simple operation.

Description

Two passage electrical stimulation devices
Technical field
The embodiment of the present invention is chiefly directed on health utilize known electro photoluminescence effect to include " office Portion's opium effect " and the two passage electrical stimulation devices of " pain gate effect ".In order to realize this New invention, introduces new electrode and electrode is arranged and the specified scheme of electrical stimulation waveforms.This Bright describing in detail realizes electric nerve retardance and adds and/or collaborative pain position or treatment position Method.
Background technology
Electro photoluminescence is already with TENS/Tens (Transcutaneous Electrical Nerve Stimulation-TENS) mode is utilizing.TENS relates to relatively low energy, and typical case Ground relates to the energy of the transmission between two surface electrodes being applied on skin.This energy with The beat frequency of 0.1Hz to 200Hz carries out amplitude modulation(PAM), sometimes carries out frequency modulation(PFM).Existing clinical literary composition Offer the biological cell effect demonstrating these frequencies on health, including contraction of muscle and lax, Vessel retraction and vasodilation and pain weaken.TENS treatment is limited to the energy that can apply Amount size is when higher energy, that energy level may become pain and non-treatment, even It is harmful.TENS treatment is bigger on textura epidermoidea's impact, and does not touch deeper tissue.
Electro photoluminescence has evolved to include, utilizes higher frequency (typically at more than 4000Hz) As " carrier wave " frequency.At higher frequencies, the resistance of health is less, thus allows higher Energy transmit in-between the electrodes without produce reaction.At higher frequencies, carrier waveform Can deeper advance in bodily tissue.
The newer beat frequency between electric stimulation 0.1Hz to 200Hz carrys out amplitude modulation(PAM) two The carrier frequency waveform of transmission between individual electrode.So, biology can be correlated with by the system of renewal Beat frequency is transferred to deeper organize.Waveform penetration depth is come really by carrier frequency is increased or decreased Fixed.For Elbow injury, possible 4000Hz is the most suitable.But, by carrier frequency is increased To about 8000Hz, treatment beat frequency deeper can be transferred to tissue.Reach in use And the carrier frequency more than 20,000Hz.This amplitude modulation(PAM) (sometimes for frequency modulation(PFM)) The carrier frequency electro photoluminescence transmitted between two electrodes is referred to as " two pole " electro photoluminescence.
Recently, four electrode electro photoluminescence are had been devised by.In this approach, electrode is typically arranged Rectangular pattern.One carrier frequency is transmitted between two corner electrodes.Second carrier frequency Transmit between contrary corner electrode.In the place that carrier frequency intersects, carrier frequency experience phase Disappear interference and constructive interference.The difference of carrier frequency produces the synthetic waveform of equivalence.Such as, if 4000Hz carrier frequency " intersects " with 4200Hz carrier frequency, then frequency synthesis is 200Hz Beat frequency (4200Hz subtracts 4000Hz=200Hz).Beat frequency occurs in and each of penetrating body The depth of the degree of depth equivalence of carrier frequency.The treatment of this form is referred to as " quadrupole " electro photoluminescence.
Two polar stimulations act directly on the tissue of base part, and will down to carrier frequency The depth penetrated.At waveform, crossing and deeper into tissue depth starts in four polar stimulations.
Have shown that carrier only frequency also can ease the pain.This is widely known by the people in medical circle.
" locally opium effect " is described as the increase of pain position natural opiate concentration.Ah Sheet is natural " anodyne ", is the method that eases the pain of health self.
" pain gate effect " is described as alleviating the pain letter marching to brain and sending from brain Number." door " relates to coming from the pain signal of pain position and marches to the passage of brain.Greatly Signal is explained by brain, and signal returns to pain position.The pain of brain is explained Determining patient's perception level to pain, this perception level is varied from according to different patients. Return to a lot of behavior of signal deciding of pain position, including inflammation.In many situations, Inflammation strengthens and the pain signal returning to brain will be caused to further enhance.This be likely to become pernicious The reponse system of circulation.Pain medicine relates to the interruption of this feedback cycle.
Summary of the invention
The present invention relates to cause local opium effect and pain gate effect to realize additional and/or association Same therapeutic value.
One embodiment of the invention relates to the use of electrical stimulation device, and described electrical stimulation device can The electronic stimulation that transmission two separates simultaneously.Typically, each of electrical stimulation device is controlled Treat output and be referred to as " passage ".By a passage, any one ordinary electrode is utilized to include suction Electrode, is applied to pain position by TENS, two pole electro photoluminescence or quadrupole electro photoluminescence.Second leads to Road is applied and is being connected at the nerve root of backbone pain position.New electrode is used at nerve root, To shroud area for treatment completely, pain gate effect causes region, carrier only frequency wave regions. Two passages transmit treatment simultaneously, although being not necessarily this situation.
TENS, two pole electro photoluminescence or quadrupole electro photoluminescence is applied in pain position, thus to known Pain relief approach produce impact.Utilizing two polar stimulations or the position of four polar stimulations, simultaneously Obtain local opium effect and pain gate effect.In the position relating to TENS, only obtain Local, top layer opium effect.In either case, locally opium frequency shows as causing pain The beat frequency scope of relieving effect is typically 50Hz to 200Hz.In this case, it is necessary to note The energy that meaning power concentrates on being transferred to pain position limits, so that contraction of muscle is limited Or do not exist.
One embodiment of the present of invention utilizes new three electrode structures and a kind of two to lead at nerve root Road electrical stimulation device.
Intactly say, system cause in pain position minimum local opium effect, and Pain is caused to gate effect by pain signal transmission to the nerve root of brain.Two kinds of effects have Add and/or synergy.Pain is reduced by the opium concentration increase of pain position.Subtract Weak signal rows proceeds to brain, gates effect at this together with the pain at related neural root and makes letter Number further weakened.Weakened pain signal is processed by brain, so that patient's sense The pain being subject to weakens, and makes the painful response signal being transferred to pain position weaken. Typically after being shorter than the period of 1 hour (60 minutes), effect reaches maximum.Additionally, By this new nerve block, pain " numb " position can accept to process further, as simply Operation.By this, there is medication analgesic structure and system realizes total consumption Reduce.
Accompanying drawing explanation
Fig. 1: show the back of patient, brain, backbone and rumpbone and spinal cord.
Fig. 2: show nerve root and extend between bone vertebra and the god that extends from rumpbone Warp, it is connected with body parts.
Fig. 3: show the nerve root leaving backbone and being connected with the elbow of patient to a certain extent Example.
Fig. 4: show the pure high_frequency sine wave being used in modern electro photoluminescence.
Fig. 5: show beat frequency may for 0.1Hz to 200Hz for cause local opium effect A pure low-frequency sine (relative to the sine wave shown in Fig. 4).
Fig. 6: show the sine wave of amplitude modulation(PAM) (AM).AM sine wave is the load of Fig. 4 The combination of the beat frequency of ripple frequency and Fig. 5.
Fig. 7: show and typically can use again or disposable electronic pads.Protruding connector includes Hole or the terminal for the treatment of waveform is inserted and then transmitted to power supply pin.
Fig. 8 A and Fig. 8 B: show typical reusable Venturi tube electrode.Electrode includes making With screw-type or the buckling connector of the pipe of electrical connection.Pipe transmission compressed air, described compression Air enters from entrance, through being opened in the aperture on inside sucker, and discharges from outlet.Logical Cross venturi-effect, air is discharged below sucker, thus produces suction, in order to by electrode Hold down on skin.Once suction electrode and skin contact, metal in suction cup carrier or lead Electrical waveform is just carried to skin from pipe by level face.Suction electrode has additional advantage, will Electrolyte takes surface to and then increases the electric conductivity on surface, and provides nutrition for body fluid.
Fig. 9: show in the way of making TENS or two pole electro photoluminescence transmit between two electrodes Two electrodes arranged.
Figure 10: show so that two different carrier frequencies are between two electrode groups separated Transmission and four electrodes arranged for the mode transmitting four polar stimulations that intersect at middle part.
Figure 11: show one embodiment of the present of invention.Show three electrodes.One electrode Receive the side of carrier only frequency.Two other electrode receives the opposite side of carrier only frequency.Three Space in dihedral is coated with carrier only frequency.
Figure 12 A and Figure 12 B: show one embodiment of the present of invention.The electrode of the present embodiment Including three electrode surfaces being incorporated in an electrode body.Three terminals allow three electricity pins to control Treat electrical stimulation signal and be carried to pad, and enter in patient body in the way of Figure 11 structure.
Figure 13 A and Figure 13 B: show one embodiment of the present of invention.The electrode of the present embodiment Including three suction electrodes including an electrode body in.Three terminals allow three pipes of charged pin Carry treatment electro photoluminescence and compressed air (or other gas), and in the way of Figure 11 structure Enter in patient body.
Figure 14: again illustrate and leave backbone and be connected with the elbow of patient to a certain extent The example of nerve root.This diagram is convenient reference for last diagram.
Figure 15: show patient body, leaves backbone and the nerve root being connected with the elbow of patient. In this example of one embodiment of the invention, the elbow pain of patient, it may be possible to " tennis elbow " Situation.Around facies cubitalis posterior, layout quadrupole electrode is arranged, thus transmits beat frequency at 0.1Hz And the quadrupole electro photoluminescence between 200Hz.New three plate electrodes of the present invention are placed on and leave ridge On the nerve root of post, and shrouding in the region of carrier only frequency, nerve root will be from pain The pain signal of position is carried to brain.
Detailed description of the invention
Fig. 1
Patient body (1000) is shown as line drawing profile, and includes brain (1005), spinal cord And backbone (1015) and rumpbone (1020) (1010).
Fig. 2
The nerve root (2005) leaving cervical vertebra, thoracic vertebrae, lumbar vertebrae and sacral is shown as covering at Fig. 1 On Suo Shi.
Fig. 3
Neural circuit (3010) is shown as dotted line, nerve root in position (3015) place from Open backbone and be connected to the pain position supposed, being elbow (3020) in this case.
Fig. 4
Show sine wave (4005), in embodiments of the present invention this sine wave (4005) table Reveal the carrier frequency of at least 4000Hz.When this sine wave is transferred to patient body, have zero Net charge, as shown in the waveform walked between a positive electrode and a negative electrode, in zero volt up and down (4010).
Fig. 5
Show sine wave (5005), in embodiments of the present invention this sine wave (5005) table Show the beat frequency between 0.1Hz and 200Hz.When this sine wave is transferred to patient body, tool There is zero net electric charge, as shown in the waveform walked between a positive electrode and a negative electrode, upper and lower in zero volt (5010).This can be the synthesis beat frequency that TENS waveform maybe can represent four polar stimulations.
Fig. 6
Show sine wave (6010), in embodiments of the present invention this sine wave (6010) table Reveal after carrying out amplitude modulation(PAM) with beat frequency sine wave (6015) between 0.1Hz and 200Hz The carrier frequency of at least 4000Hz.This is the example of two polar stimulations.When this sine wave is transferred to During patient body, there is zero net electric charge, as from shown in the waveform walked between positive pole and negative pole, In zero volt up and down (6005).
Fig. 7
Circular electrode (7005) is conventional design, and the most a diameter of 1.25 inches, There is the terminal (7010) connected for electricity pin (in this example for the pin of 2mm diameter), Wherein terminal and electricity pin are the most typical.Electrode (7005) can be by a lot of materials Material is made.In some cases, electrode (7005) is non-conductive, and with wire by terminal (7010) It is connected to the conductive surface on the bottom of electrode (7005).Under other circumstances, electrode (7005) Top conductive, and the lower section of electrode (7005) has the conducting resinl adhering to skin.At it Under its situation, such as doped with the silicon rubber of a large amount of carbon blacks when, whole electrode (7005) Conduction.With band or other device, pad is fixed to skin.In some cases, conducting resinl is used Or even non-distilled water is formed and the electrically connecting completely of skin.
Fig. 8 A and Fig. 8 B
Circular magnetic chuck (8005) is shown as on top having and comprises threaded metallic rod (8010) Terminal.Compressed air and the signal of telecommunication (8920) are sent into terminal by the pipe of electrical connection.The signal of telecommunication (8920) conductive plane (8015) it is transferred to.Compressed air enters threaded metallic rod (8010), entered in sucker (8005) by the hole on conductive plane (8015), and Discharge from the other end of bar as compressed air stream (8930).By in sucker (8005) Air is discharged in sucker (8005) by the compressed air that hole enters, and when being applied to such as During the surface of skin, attracted downwards sucker (8005) by suction.This suction passes through Wen Tube effect produces.When conductive plane (8015) is attracted to skin contact, by electro photoluminescence It is transferred to patient.
Sucker (8005) is typically by flexible but fluid-resistant and be biological inert non-conducting material Make, such as silicon rubber.Threaded shank is as conductive plane (8015), typically by gold Belong to structure.
Fig. 9
Show two electrodes (9005) and (9010) being configured at TENS or two polar stimulations. Electro photoluminescence (9015) is transmitted between two electrodes (9005) and (9010).Can be assumed that, Electrode (9005) contacts with patient skin with (9010).
Figure 10
Showing two electrodes (10,005), the carrier only being illustrated by the broken lines (10,030) is two Transmit between individual electrode (10,005).Show two extra electrodes (10,010), by reality The carrier only (10,020) that line represents transmits between two electrodes (10,010).Can be assumed that, Electrode contacts with patient skin.In the structure shown here, two carrier waves (10,020) and (10,030) In the local interaction that they intersect, and formed not by constructive interference and destructive interference Same waveform.In this case, four polar stimulations are transmitted in electrode (10,005) and (10,010).
Figure 11
Show and receive two electrodes (11,005) of an identical electrical connection and receive electrical connection The 3rd electrode (11,010) of opposite side.Carrier only frequency (11,020) is in electrode (11,005) And transmit between electrode (11,010).Stimulate and directly do not transmit as shown in arrow, and It is to occur in triangle.It can be assumed that electrode (11,005) and (11,010) and patient's skin Skin contacts.
Figure 12 A and Figure 12 B
Show the electrode (12,005) of one embodiment of the invention.Electrode (12,005) comprises There are three terminals (12,010) for the 2mm hole of electricity pin (common in the art) connection (12,015).The conductive pad included below (12,020) of electrode (12,005) and (12,030). Two conductive pads (12,020) receive an identical electrical connection, and the 3rd conductive pad (12,030) Receive the opposite side of electrical connection.Carrier only frequency is at two conductive pads (12,020) and conductive pad (12,030) transmit between.Stimulate and formed by conductive pad (12,020) and (12,030) Transmission in triangle.It can be assumed that conductive pad (12,020) and (12,030) and patient skin Contact.
Figure 13 A and Figure 13 B
Show the electrode (13,005) of one embodiment of the invention.Electrode (13,005) comprises Allow three threaded metal terminals that transmission electro photoluminescence and compressed-air actuated pipe are attached And (13,015) (13,010).Electrode (13,005) lower section comprises suction electrode (13,020) (13,030).Two suction electrodes (13,020) receive an identical electrical connection, and 3rd suction electrode (13,030) receives the opposite side of electrical connection.Carrier only frequency is two suctions Transmit between electrode (13,020) and suction electrode (13,030).Stimulate by suction electrode And transmission in (13,030) triangle of being formed (13,020).It can be assumed that suction electrode (13,020) and (13,030) contact with patient skin, and when suction electrode (13,020) When (13,030) are compressed because of the gravitation of venturi-effect, suction electrode (13,020) and (13,030) conductive plane (8015) is attracted to downwards skin.
Figure 14
Neural circuit (14,010) is shown as dotted line, nerve root in position (14,015) place Leave backbone, and be connected to the pain position supposed, be elbow (14,020) in this case. This diagram is consistent with Fig. 3, and is to illustrate for the ease of last diagram reference.
Figure 15
Show one embodiment of the present of invention.Patient body be shown as having brain (15,020) and Spinal cord and nerve (15,010), nerve is expressed as dotted line and by the pain position on elbow (15,005) spinal cord with suitable backbone position (15,015) is connected.
As embodiments of the invention, bag is placed in the position leaving backbone in neural (15,010) Triangular-shaped electrodes (15,030) containing three conductive pads or three suction electrodes.
Put around pain position (15,005) (situation being likely to occur in such as " tennis elbow ") Put four common electrodes or suction electrode (15,025).
The triangular-shaped electrodes (15,030) of one embodiment of the invention is shrouded by carrier only frequency stimulation The nerve root of nerve (15,010), thus cause pain to gate effect.Quadrupole around elbow Electrode structure (15,025) transmission quadrupole electro photoluminescence, thus cause local opium effect.
Two kinds of effects have additional and/or synergy.By increasing pain position (15,005) The opium concentration at place reduces pain.The signal rows weakened proceeds to brain (15,020), at this together with Pain at related neural root gates effect and makes signal the most weakened.Brain (15,020) is right Weakened pain signal processes so that patients' feeling to pain weaken, and The painful response signal being transferred to pain position (15,005) place is made to weaken.Typically it is being shorter than 1 After the period of hour (60 minutes), effect reaches maximum.Additionally, by this new neural resistance Stagnant, pain " numb " position can accept to process further, such as simple operation.Logical Cross this structure showing medication analgesic effect and system to realize the reduction of total consumption.

Claims (1)

1. a two passage electrical stimulation device, the electro photoluminescence that its transmission two separates;Wherein: bag Include the electrode for electric nerve retardance, wherein: described electrode be shaped as triangle, and wrap Include two conductive surfaces receiving the identical signal of telecommunication and the 3rd conduction receiving another signal of telecommunication Surface;Carrier only transmits between conductive surface and the 3rd conductive surface, and electro photoluminescence is led at two Transmission in the triangle that ammeter face and the 3rd conductive surface are formed;Conductive surface and the 3rd conductivity meter Face contacts with patient skin;
By this be used for electric nerve retardance electrode be placed on pain position is connected with brain nerve On nerve root, and wherein two or four electrode structure is placed on around pain position;
Wherein said two or four electrode structure passes through TENS, two poles, quadrupole in pain position Place's transmission electro photoluminescence, or transmit frequency or beat frequency stimulation between 0.1Hz and 200Hz.
CN201210107368.9A 2012-04-12 2012-04-12 Two passage electrical stimulation devices Active CN103372262B (en)

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CN103656851B (en) * 2012-09-19 2015-12-02 安徽瑞德医疗设备制造有限公司 Three node electrodes blocked for causing electric nerve and electric nerve retarding system
CN106573139B (en) * 2014-01-17 2019-09-06 心脏起搏器股份公司 System and method for delivering lung treatment
US10413731B2 (en) 2014-01-17 2019-09-17 Cardiac Pacemakers, Inc. Selective nerve stimulation using presynaptic terminal depletion block
CN104888346B (en) * 2014-12-21 2020-10-13 徐志强 Method and device for performing nerve stimulation on coma brain

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US5501703A (en) * 1994-01-24 1996-03-26 Medtronic, Inc. Multichannel apparatus for epidural spinal cord stimulator
US7254444B2 (en) * 2001-10-17 2007-08-07 Encore Medical Asset Corporation Electrical nerve stimulation device
GB2422549A (en) * 2005-02-01 2006-08-02 Wound Solutions Ltd Flexible electrodes comprising a honey-comb mesh and integrated wound stimulation treatment devices
CN2850633Y (en) * 2005-12-02 2006-12-27 内蒙古医学院 Nerve stimulation blocking apparatus
US8612008B2 (en) * 2008-10-23 2013-12-17 Electromedical Products International, Inc. Microcurrent and cranial electrotherapy stimulator for control of anxiety, insomnia, depression and pain

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