CN103341231B - The doser of visual intraluminal tissue and method thereof - Google Patents
The doser of visual intraluminal tissue and method thereof Download PDFInfo
- Publication number
- CN103341231B CN103341231B CN201310300707.XA CN201310300707A CN103341231B CN 103341231 B CN103341231 B CN 103341231B CN 201310300707 A CN201310300707 A CN 201310300707A CN 103341231 B CN103341231 B CN 103341231B
- Authority
- CN
- China
- Prior art keywords
- sacculus
- micropin
- pipe
- topping
- doser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Abstract
The present invention relates to a kind of doser of visual intraluminal tissue, it comprises syringe pump, sacculus topping up pipe, monitoring air bag, micropin sacculus, micropin, photographic head, display device, foley's tube and seal wire guiding tube; The outbound port of syringe pump is provided with current meter; Sacculus topping up pipe is connected to the side of the syringe pump port of export, and its entrance point is provided with effusion meter and drawing liquid joint; Monitoring air bag is electrically connected with display device; Micropin sacculus is connected to the port of export of sacculus topping up pipe; Micropin is located on micropin sacculus; Photographic head is electrically connected with display device.Medication comprises pathological tissues location successively, pathological tissues enters, to pathological tissues loading and disengaging pathological tissues four step.Doser of the present invention not only structural design is simple, reasonable, and simple to operate, and cost is low.Medication step of the present invention is simple, can not only realize the accurate location to pathological tissues, and whole administration process is simple, easy and efficiency is high.
Description
Technical field
The present invention relates to field of medical technology, particularly relate to a kind of doser and method thereof of visual intraluminal tissue.
Background technology
The existing technology of intraluminal tissue top layer administration of giving mainly contains following three kinds:
1, micropin medicine-feeding technology
Mainly use entry needle conventionally by percutaneous drug delivery, but this method brings misery to patient, there is larger infection risk because wound is comparatively large simultaneously, and long-time continuous administration can not be realized.Although percutaneous plaster solves problem above, due to the obstruction of the human body natural cover for defense, the bioavailability of medicine is reduced.
Some diseases in body cavity, the atherosclerosis of such as Endovascular, hemangioma, the myocardial infarction of the chambers of the heart, gastral digestive tract ulcer, ulcerative colitis, Crohn ' sdisease etc., Formulations for systemic administration is difficult to ensure at the drug level of affected area, and whole body side reaction is more, improve affected area drug level by topical, reasonable therapeutic effect can be obtained.Current endoceliac topical mainly TAI(transcatheterarterialinfusion) and the interventional technique such as chamber mirror technology realize.The intracavity topical modes of main application clinically has following several at present: 1. by special foley's tube topical, as dual balloon catheter, permeate conduit, foley's tube with holes, way film foley's tube etc.; 2. by intervention support topical, it mainly adopts certain methods to be coated on support by medicine, and after putting into support, medicine is had an effect by method slow releasing such as simple diffusion or chemical actions; 3. ionize infiltration administration, conduit is put into diseased region as a motor to the effect that according to the principle of ionization therapy, and is formed certain electrical gradient by it, and the medicine of sacculus release permeates along certain electrical gradient to chamber wall; 4. by special carrier administration, take these special carriers to diseased region by intervention measures such as foley's tubes, make medicine and pathological changes tube wall specific bond, thus strengthen the picked-up of tube wall to medicine or the Local Residence Time of prolong drug; 5. the subsidiary catheter perfusion medicine of chamber mirror is passed through.But in the mode of above-mentioned topical, medicine is all to be confined to the mucosa of tube chamber or the intimal surface of blood vessel, still exists by the absorption problem compared with depths focus.
At present, a kind of Epidermal administration method that can break through keratodermatitis---skin micropin medication has been had both at home and abroad.Number be in the patent of invention of US2007/7226439B2 in invention, inventors herein propose the injection device that a kind of micropin adds elasticity medicament storage, micropin improves the permeability of skin to transdermal drug by pricking small hole on the horny layer of skin.Number be CN1562402A in invention, inventors herein propose the method for metal micro-needle sequence in epiderm skin administration and the manufacture method of micropin.The treatment that current micropin technology has been applied to some dermatosis uses, if MicroneedleTherapySystem is in skin wrinkle removal, scar of dispelling, comedo, the application in alopecia etc.; But this micropin can only be used in percutaneous drug delivery field, namely can only external, can not realize effective administration in body cavity, the suitability is limited.
2, diagnosis and treatment visualization technique
At present, electronic gastroscope, intestinal mirror and branchofiberoscope have been widely used in the diagnosis of digestive tract and respiratory tract disease.Medical electronic endoscope, referred to as electronic gastroscope, primarily of three part compositions: scope, video processor and TV monitor.Also be equipped with some auxiliary device, as videocorder, photographing unit, suction pump and being used for inputs the keyboard of various information and diagnoses and treatment various treatment apparatus etc. used.Lead and be made up of CCD and cable as system, its imaging depends on the miniature image sensor of shank head end equipment.The image-forming principle of fujinon electronic video endoscope is the light utilizing the light source of TV information center equipment to send, optical fibers in scope imports light into acceptor intracavity, ccd image sensor receives the light that in body cavity, mucosal surface reflection comes, convert this light to the signal of telecommunication, by wire, signal is transported to TV information center again, through TV information center, these signals of telecommunication are passed through storage and process again, be finally transferred in TV monitor the colored mucosa image demonstrated on screen by inspection internal organs.Produce the Ya Lun (WelchAllyn) of the more famous company of video image dendoscope by the U.S. and the Olympus (Olympas) etc. of Japan in the world.Intestinal mirror is similar to its principle with bronchoscope.The technical development of video image dendoscope extends our eyes, and let us sees real focus.But, adopt separately scope can only be find focus, can not effectively solve problems such as focus administrations.
3, foley's tube technology
Conduit is the main tool of interventional therapy, and foley's tube is linked together at conduit and inflatable sacculus, thus can reach blood vessel dilating wall, struts the effects such as intervention support.Independent employing sacculus can only play the effect of expansion tract, but can not use the treatment meanss such as administration to the focus in tract, function is relatively single, economical and practical not.
But because above-mentioned three kinds of technical functionalitys are relatively single, the suitability is limited, and therapeutic effect is not good enough.Due on the market at present also not by the situation that above-mentioned three kinds of combine with technique utilize together, therefore, be badly in need of design complete function, the method for the visual intraluminal tissue administration that therapeutic effect is good and economical and practical and device thereof.
Summary of the invention
The present invention is to solve existing, poor effect low to the technology therapeutic efficiency of intraluminal tissue top layer administration and the high problem for the treatment of cost and propose one and can not only realize the administration of visual intracavity lesion tissue positioned accurately and efficiently, the doser of the visual intraluminal tissue that therapeutic effect is good and economical and practical and method thereof.
The present invention is achieved by the following technical solutions:
The doser of above-mentioned visual intraluminal tissue, described doser comprises syringe pump, sacculus topping up pipe, monitoring air bag, micropin sacculus, micropin, photographic head, display device, foley's tube and seal wire guiding tube; The outbound port of described syringe pump is provided with current meter; Described sacculus topping up pipe is connected to the side of the described syringe pump port of export by described foley's tube, its entrance point is also provided with effusion meter and drawing liquid joint; Described monitoring air bag to be located on described sacculus topping up pipe and to be electrically connected with described display device; Described micropin sacculus is connected to the port of export of described sacculus topping up pipe; Described micropin is located on described micropin sacculus, and it is porose microneedle configuration and endoporus communicates with the inner chamber of described micropin sacculus; Described photographic head is positioned at described micropin sacculus side and is electrically connected with described display device by described seal wire guiding tube.
The doser of described visual intraluminal tissue, wherein: described monitoring air bag and described sacculus topping up pipe are the integrative-structure of moulding by casting; Described monitoring air bag communicates with described sacculus topping up pipe inside and side is also provided with pressure transducer; The inner chamber of described monitoring air bag is pierced in described pressure transducer one end, and the other end is electrically connected with described display device by described seal wire guiding tube.
The doser of described visual intraluminal tissue, wherein: be drawn by described display device for connecting the seal wire guiding tube of described photographic head, then wears described sacculus topping up pipe and micropin sacculus and right-hand member to described micropin sacculus stretches out successively; Described photographic head is connected to the end of that section of seal wire guiding tube stretched out to described micropin sacculus right-hand member.
The doser of described visual intraluminal tissue, wherein: described seal wire guiding tube wears with described sacculus topping up pipe and micropin sacculus the position connected and all adopts moulding by casting.
A kind of medication of doser of visual intraluminal tissue, it is characterized in that, comprise the following steps: (1) pathological tissues is located: at first related for micropin sacculus micropin one is slowly inserted pathological tissues intracavity, and then by the display on display device, micropin sacculus is accurately delivered to pathological tissues together with micropin; (2) pathological tissues is entered: after above-mentioned steps (1) completes, in sacculus topping up pipe, injecting liquid by syringe pump makes micropin sacculus fill, then micropin tip is affixed towards pathological tissues with pathological tissues surface by the change of monitoring air bag monitoring pressure outside pathological tissues chamber, then strengthening syringe pump air pressure makes micropin tip insert pathological tissues top layer, when in monitoring air bag, pressure reaches a certain scope and comparatively stablizes, micropin has entered pathological tissues top layer and has completed; (3) to pathological tissues loading: after above-mentioned steps (2) completes, open effusion meter, accelerate the injection speed of syringe pump, make the medicine of doses be transported in pathological tissues by the inner passage of micropin sacculus and micropin; (4) pathological tissues is departed from: after above-mentioned steps (3) completes, namely after reaching injection measurement, the medicine in micropin sacculus is extracted out by drawing liquid joint, micropin sacculus is diminished, micropin and pathological tissues surface are departed from, finally under the guiding of seal wire guiding tube, sacculus topping up pipe is extracted out outside pathological tissues chamber.
Beneficial effect:
The doser structural design of the visual intraluminal tissue of the present invention is simple, rationally, the doser that it is foley's tube technology, micropin technology and fujinon electronic video endoscope technology combine; Especially, combine to use by sacculus and micropin to make medicine can not only enter into the mucosa of tube chamber or the intimal surface of blood vessel comprehensively, and makes to be significantly improved compared with the drug absorption efficiency of depths focus; By photographic head and display device with the use of pathological tissues can be located accurately and efficiently, ensure that the safety of whole administration process; Moreover, effectively can ensure safety that whole doser operates in administration process, reliability by the design of current meter, effusion meter and monitoring air bag.Meanwhile, seal wire guiding tube can play the effect guiding micropin sacculus to enter pathological tissues intracavity.Whole doser is not only simple to operate, and can efficiently, accurately realize the administration of visual intracavity lesion tissue positioned, and therapeutic efficiency is high, effective, economical and practical, is suitable for propagation and employment.
The medication of the doser of the visual intraluminal tissue of the present invention, step is simple, effectively can not only realize the location accurately and efficiently of organizing visual intracavity lesion, and the safety of whole administration process, reliability are higher, and therapeutic effect is good.
Accompanying drawing explanation
Fig. 1 is the structural representation of the doser of the visual intraluminal tissue of the present invention.
Detailed description of the invention
The "left", "right" related in the present invention, " on " and " interior " description scheme the noun of locality all with the structure of the doser of visual intraluminal tissue in accompanying drawing 1 towards consistent.
The doser of the visual intraluminal tissue of the present invention, comprises syringe pump 1, sacculus topping up pipe 2, monitoring air bag 3, micropin sacculus 4, micropin 5, photographic head 6, display device 7, foley's tube 8 and seal wire guiding tube 9.
Syringe pump 1 is the high order end of whole doser, it is combined by the pump housing 11 and piston 12, the port of export of this syringe pump 1 is also provided with current meter 13, this current meter 13 detects flow velocity during syringe pump 1 injecting fluid in good time, to avoid syringe pump 1 flow velocity excessive or too smallly bring impact to whole administration process.
Sacculus topping up pipe 2 is connected to the side of syringe pump 1 port of export by foley's tube 8, the entrance point of this sacculus topping up pipe 2 is also provided with effusion meter 21 and drawing liquid joint 22, wherein, in the present embodiment, this effusion meter 21 is specifically connected on the foley's tube 8 of sacculus topping up pipe 2 side; When monitoring pressure stability in air bag 3, namely micropin 5 starts as opening after top layer undertissue injectable drug, and this effusion meter 21 can monitor injection volume.
Monitoring air bag 3 is located at sacculus topping up pipe 2 side and is the integrative-structure of moulding by casting with sacculus topping up pipe 2, the inner chamber of this monitoring air bag 3 communicates with sacculus topping up pipe 2 inside and is also provided with pressure transducer 31, wherein, this pressure transducer 31 is electrically connected with display device 7 by seal wire guiding tube 9, can the pressure signal in monitoring air bag 3 be passed to display device 7 and show in good time.
Micropin sacculus 4 is positioned at the port of export of sacculus topping up pipe 2 and is connected as a single entity with sacculus topping up pipe 2; The length of this micropin sacculus 4 can be selected according to different tracts, and its suitableeest full diameter can become according to different tract diameters.
Micropin 5 is in array-like arrangement and is arranged on micropin sacculus 4, and it is the porose microneedle configuration of metal and endoporus communicates with the inner chamber of described micropin sacculus 4; The array size of this micropin 5 can be determined according to different pathological changes sizes.Wherein, this micropin 5 can be positioned at the side of micropin sacculus 4, also can be positioned at the tip of micropin sacculus 4, and in the present embodiment, this micropin 5 is positioned at the side of micropin sacculus 4; The tip diameter of micropin 5 is 10nm ~ 10 μm, and base diameter is 20-300 μm, highly depending on different tissues skin depth.
Photographic head 6 is positioned at the right-hand member of micropin sacculus 4, it is electrically connected with display device 7 by seal wire guiding tube 9, wherein, this seal wire guiding tube 9 being used for connecting photographic head 6 is drawn by display device 7, and then wearing sacculus topping up pipe 2 and micropin sacculus 4 successively and right-hand member to micropin sacculus 4 stretches out, namely this photographic head 6 is located at the end of that section of seal wire guiding tube 9 stretched out to micropin sacculus 4 right-hand member; Wherein, the position that seal wire guiding tube 9 connects with capsule topping up pipe 2 and micropin sacculus 4 is all moulding by casting.
The medication of the doser of the visual intraluminal tissue of the present invention, comprises the following steps:
1, pathological tissues location
At first related for micropin sacculus 4 micropin 5 one is slowly inserted pathological tissues intracavity, and then by the display on display device 7, micropin sacculus 4 is accurately delivered to pathological tissues together with micropin 5;
2, pathological tissues is entered
After above-mentioned steps (1) completes, micropin sacculus 4 is filled by syringe pump 1 to injection of medicine in sacculus topping up pipe 2, now by the monitoring air bag 3 monitoring pressure change outside pathological tissues chamber, micropin 5 tip is affixed towards pathological tissues with pathological tissues surface, then strengthening syringe pump 1 air pressure makes micropin 5 tip insert pathological tissues top layer, when monitoring pressure in air bag 3 and reaching a certain scope (different tissue surface pressure limits is different) and comparatively stablize, micropin 5 enters pathological tissues top layer and completes;
3, to pathological tissues loading
After above-mentioned steps (2) completes, open effusion meter 21, accelerate the injection speed of syringe pump 1, make the medicine of doses be transported in pathological tissues by the inner passage of micropin sacculus 4 and micropin 5;
4, pathological tissues is departed from
After above-mentioned steps (3) completes, namely after reaching injection measurement, extract the medicine in micropin sacculus 4 out by drawing liquid joint 22, micropin sacculus 4 is diminished, micropin 5 and pathological tissues surface are departed from, finally under the guiding of seal wire guiding tube 9, sacculus topping up pipe 2 is extracted out outside pathological tissues chamber.
The apparatus structure simplicity of design of the visual intraluminal tissue administration of the present invention, rationally, the doser that it is foley's tube, micropin technology and fujinon electronic video endoscope technology combine, not only simple to operate, and the administration of visual intracavity lesion tissue positioned can be realized efficiently, accurately, therapeutic efficiency is high, effective, economical and practical, be suitable for propagation and employment.
The present invention's visual intraluminal tissue medication is the device in conjunction with visual intraluminal tissue administration, and step is simple, can not only realize the accurate location to pathological tissues, and whole administration process is simple, easy and efficiency is high.
Claims (3)
1. a doser for visual intraluminal tissue, is characterized in that: described doser comprises syringe pump, sacculus topping up pipe, monitoring air bag, micropin sacculus, micropin, photographic head, display device, foley's tube and seal wire guiding tube;
The outbound port of described syringe pump is provided with current meter;
Described sacculus topping up pipe is connected to the side of the described syringe pump port of export by described foley's tube, its entrance point is also provided with effusion meter and drawing liquid joint;
Described monitoring air bag to be located on described sacculus topping up pipe and to be electrically connected with described display device; Described monitoring air bag and described sacculus topping up pipe are the integrative-structure of moulding by casting;
Described monitoring air bag communicates with described sacculus topping up pipe inside and side is also provided with pressure transducer; The inner chamber of described monitoring air bag is pierced in described pressure transducer one end, and the other end is electrically connected with described display device by described seal wire guiding tube;
Described micropin sacculus is connected to the port of export of described sacculus topping up pipe;
Described micropin is located on described micropin sacculus, and it is porose microneedle configuration and endoporus communicates with the inner chamber of described micropin sacculus;
Described photographic head is positioned at described micropin sacculus side and is electrically connected with described display device by described seal wire guiding tube.
2. the doser of visual intraluminal tissue as claimed in claim 1, it is characterized in that: be drawn by described display device for connecting the seal wire guiding tube of described photographic head, then wear described sacculus topping up pipe and micropin sacculus successively and right-hand member to described micropin sacculus stretches out;
Described photographic head is connected to the end of that section of seal wire guiding tube stretched out to described micropin sacculus right-hand member.
3. the doser of visual intraluminal tissue as claimed in claim 2, is characterized in that: described seal wire guiding tube wears with described sacculus topping up pipe and micropin sacculus the position connected and all adopts moulding by casting.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310300707.XA CN103341231B (en) | 2013-07-17 | 2013-07-17 | The doser of visual intraluminal tissue and method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310300707.XA CN103341231B (en) | 2013-07-17 | 2013-07-17 | The doser of visual intraluminal tissue and method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103341231A CN103341231A (en) | 2013-10-09 |
| CN103341231B true CN103341231B (en) | 2016-04-06 |
Family
ID=49276088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310300707.XA Expired - Fee Related CN103341231B (en) | 2013-07-17 | 2013-07-17 | The doser of visual intraluminal tissue and method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103341231B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106426729A (en) * | 2016-11-09 | 2017-02-22 | 江苏信息职业技术学院 | Semiconductor microneedle assembly based on gene therapy, manufacturing method and manufacturing mold |
| CN106386780A (en) * | 2016-12-09 | 2017-02-15 | 无锡丹卡科技有限公司 | Visual multi-functional anticorrosion injection and pumping device |
| CN209790103U (en) * | 2018-04-21 | 2019-12-17 | 李皇德 | Drug release device for blood vessel saccule and saccule support |
| CN109009588A (en) * | 2018-07-27 | 2018-12-18 | 王才阳 | A kind of Cardiological intravascular stent system and application method |
| CN110811524A (en) * | 2019-11-08 | 2020-02-21 | 武汉佑康科技有限公司 | Visual thermotherapy device |
| CN113018660A (en) * | 2021-03-16 | 2021-06-25 | 中国科学技术大学 | Microneedle balloon for interventional drug delivery |
| CN114569868A (en) * | 2022-03-01 | 2022-06-03 | 中国人民解放军西部战区总医院 | Novel double-layer medicine balloon |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101051232A (en) * | 2006-06-09 | 2007-10-10 | 四川大学华西医院 | Automatic regulating and control instrument in conduit pipe sacculus |
| CN101420913A (en) * | 2006-02-24 | 2009-04-29 | 高尔韦爱尔兰国立大学 | Minimally invasive intravascular treatment device |
| CN201847995U (en) * | 2010-10-15 | 2011-06-01 | 张金宇 | Visual tracheal cannula guide wire |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8532734B2 (en) * | 2008-04-18 | 2013-09-10 | Regents Of The University Of Minnesota | Method and apparatus for mapping a structure |
| IL286546B (en) * | 2011-03-07 | 2022-09-01 | Smart Medical Systems Ltd | Balloon-equipped endoscopic devices and methods thereof |
-
2013
- 2013-07-17 CN CN201310300707.XA patent/CN103341231B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101420913A (en) * | 2006-02-24 | 2009-04-29 | 高尔韦爱尔兰国立大学 | Minimally invasive intravascular treatment device |
| CN101051232A (en) * | 2006-06-09 | 2007-10-10 | 四川大学华西医院 | Automatic regulating and control instrument in conduit pipe sacculus |
| CN201847995U (en) * | 2010-10-15 | 2011-06-01 | 张金宇 | Visual tracheal cannula guide wire |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103341231A (en) | 2013-10-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103341231B (en) | The doser of visual intraluminal tissue and method thereof | |
| US20050038319A1 (en) | Gastrointestinal tool over guidewire | |
| Obstein et al. | Advanced endoscopic technologies for colorectal cancer screening | |
| CN106922123A (en) | Pericardium enters device | |
| JPH11500021A (en) | Method and apparatus for administering or aspirating a substance along the entire gastrointestinal tract | |
| US20140206940A1 (en) | Method of tissue separation using fluidic pulses to minimize tissue trauma during catheter insertion | |
| US20140088457A1 (en) | Bleeding containment device | |
| CN107583172A (en) | The dual lumen nasogastric tube Nasal cavity intestinal tube composite conduit that a kind of ultrasonic guidance intranasal is inserted | |
| CN201422864Y (en) | Visual optical fiber and catheter interventional treatment instrument for tooth root periodontitis | |
| CN203059650U (en) | Visible urethra probe used for indwelling catheter | |
| JP6753655B2 (en) | Medical equipment | |
| CN105079945B (en) | A kind of alimentary canal double-layer seal formula balloon tube | |
| CN104783775B (en) | A kind of ureter with real-time pressure detection and adsorption capacity imports sheath | |
| CN206355382U (en) | A kind of visible enema apparatus for treating ulcerative colitis | |
| CN215608679U (en) | Biliary tract three-cavity balloon photography catheter system | |
| CN201755226U (en) | Left and right atrium combined piezometer tube | |
| JP2011087859A (en) | Endoscope and blood vessel endoscope system using the same | |
| CN210019557U (en) | Visual chest and abdomen water injection and suction device and auxiliary device thereof | |
| CN204601362U (en) | New disposable endoscope entry needle | |
| CN206867206U (en) | Electronics angioscope | |
| CN209984184U (en) | Bronchoscope outer sleeve balloon | |
| CN212756824U (en) | Disposable heart catheter panoramic endoscopic and drug administration device | |
| JP6358594B2 (en) | Blood flow maintenance type angioscope system | |
| CN206166894U (en) | Bronchoscope nasal cavity sheath | |
| CN216963282U (en) | Series double-balloon drug delivery system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Yu Kun Inventor before: Yu Kun Inventor before: Di Yonghui Inventor before: Xiao Linlin Inventor before: Song Rui |
|
| COR | Change of bibliographic data | ||
| GR01 | Patent grant | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160315 Address after: 610000, No. 3, building 3, No. 1480, No. 9, No. 1, Tianfu Road, Chengdu hi tech Development Zone, Sichuan Applicant after: Chengdu Gencelltech Biotechnology Co., Ltd. Address before: West high tech Zone Fucheng Road in Chengdu city of Sichuan province 610000 399 No. 5 Building 1 unit 13 floor No. 13 Applicant before: Chengdu Gencelltech Biotechnology Co., Ltd. |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160406 Termination date: 20210717 |