CN103330923B - A kind ofly treat external-applied ointment of old osteoarthritis and preparation method thereof - Google Patents
A kind ofly treat external-applied ointment of old osteoarthritis and preparation method thereof Download PDFInfo
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- CN103330923B CN103330923B CN201310219607.4A CN201310219607A CN103330923B CN 103330923 B CN103330923 B CN 103330923B CN 201310219607 A CN201310219607 A CN 201310219607A CN 103330923 B CN103330923 B CN 103330923B
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Abstract
The invention discloses a kind of external-applied ointment for the treatment of old osteoarthritis, it is made up of the raw material of following weight parts: Radix Rehmanniae 10-20, Rhizoma Curculiginis 10-20, Ramulus Mori 10-20, Radix Aconiti Kusnezoffii Preparata 10-12, Herba Epimedii 10-15, Radix Stephaniae Tetrandrae 10-12, Scorpio 3-4, Pericarpium Metaplexis 10-12, Folium Artemisiae Argyi 5-7, Rhizoma Kaempferiae 5-7, Resina Ferulae 8-10, Radix Aconiti Preparata 6-8, Caulis Piperis Kadsurae 6-7, Radix Jujubae 4-5, Cortex Cinnamomi 9-10, Radix Saposhnikoviae 10-13, Ramulus Pini 10-12, Pericarpium Citri Reticulatae 7-10, Rhizoma Zingiberis Recens 4-6, Cortex ulmi pumilae 3-5, Rhizoma Et Radix Notopterygii 6-10, Radix Paeoniae Rubra 10-20, Zaocys 10-15; Ointment determined curative effect of the present invention, component are reasonable, and have promoting blood circulation to remove obstruction in the collateral, clearing away damp-heat, except arthralgia pain, improve the effect such as microcirculation, relaxing muscles and tendons regulating menstruation, life-time service is safe and effective, has no side effect.
Description
Technical field
The present invention relates generally to a kind of external-applied ointment for the treatment of old osteoarthritis, belongs to field of medicaments.
Background technology
The medicine of the old osteoarthritis of current treatment comprises several below: anti-inflammatory analgesic medicine: external first-selected acetaminophen, this medicine good analgesic effect, untoward reaction is few, and expense is low.Usual 1 daily amount is no more than 3g, but long-term, high-dose use has the report causing liver or injury of kidney.If this type of medicine analgesic effect is not obvious or with knee joint-effusion, should select other drug.Nonsteroidal antiinflammatory drug (NSAIDs): this kind of medicine has antiinflammatory, pain relieving and refrigeration function treats the most frequently used medicine of osteoarthritis.But the aspirin wherein had, salicylic acid, Phenylbutazone, indomethacin and naproxen etc., have inhibitory action to the synthesis of articular cartilage matrix Dan Baiduotang proteoglycan PG, be unfavorable for osteoarthritis, should not select, at least do not answer life-time service.Other medicines, as diclofenac, meloxicam, nabumetone, etodolac, sulindac and acemetacin etc., have no adverse effects to the synthesis of cartilage matrix protein polysaccharide, even have promotion anabolic effect, be suitable for selecting.And, there is the gastrointestinal safety suitable with specific C OX-2 inhibitor as the meloxicam of selectivity COX-2 (COX-2) inhibitor, etodolac and nabumetone etc., and few to the harmful effect of cardiovascular and kidney.
Summary of the invention
The object of the invention is just to provide a kind of external-applied ointment for the treatment of old osteoarthritis.
The present invention is achieved by the following technical solutions:
Treat an external-applied ointment for old osteoarthritis, it is made up of the raw material of following weight parts:
Radix Rehmanniae 10-20, Rhizoma Curculiginis 10-20, Ramulus Mori 10-20, Radix Aconiti Kusnezoffii Preparata 10-12, Herba Epimedii 10-15, Radix Stephaniae Tetrandrae 10-12, Scorpio 3-4, Pericarpium Metaplexis 10-12, Folium Artemisiae Argyi 5-7, Rhizoma Kaempferiae 5-7, Resina Ferulae 8-10, Radix Aconiti Preparata 6-8, Caulis Piperis Kadsurae 6-7, Radix Jujubae 4-5, Cortex Cinnamomi 9-10, Radix Saposhnikoviae 10-13, Ramulus Pini 10-12, Pericarpium Citri Reticulatae 7-10, Rhizoma Zingiberis Recens 4-6, Cortex ulmi pumilae 3-5, Rhizoma Et Radix Notopterygii 6-10, Radix Paeoniae Rubra 10-20, Zaocys 10-15.
Treat a preparation method for the external-applied ointment of old osteoarthritis, comprise the following steps:
(1) add above-mentioned Radix Saposhnikoviae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae by after Mel heated and boiled, low baking temperature infiltrates 10-15 minute, takes out and is placed in food steamer, steam 3-5 minute at 80-90 DEG C, and take out, drying grinds into powder; Be covered with one deck bottom described food steamer in vinegar, soak the Folium Crataegi taken out after 10-20 minute, the consumption of described Mel is the 5-7% of Radix Saposhnikoviae;
(2) after Oryza glutinosa, Fructus Jujubae being added water and boil, filter, obtain Fructus Jujubae Rice & peanut milk, above-mentioned Rhizoma Curculiginis, Folium Artemisiae Argyi are joined in Fructus Jujubae Rice & peanut milk, add a cover, low baking temperature boils in a covered pot over a slow fire 8-10 minute processed, take out, drying grinds into powder, and the weight ratio of described Oryza glutinosa and Fructus Jujubae is 8-10:1, and the amount of reusing of described Fructus Jujubae Rice & peanut milk is the 10-14% of Rhizoma Curculiginis weight;
(3) each for residue raw material is added flooding 3-4 time, filter cleaner, merging filtrate, concentrate drying, grind into powder;
(4) by each powder mixing and stirring obtained above, the external-applied ointment of the old osteoarthritis of described treatment is obtained.
A kind of external-applied ointment for the treatment of old osteoarthritis, this ointment in use, after the glycerol mixing and stirring of the Ovum Gallus domesticus album of its quality 50-60%, 0.1-0.3%, be coated on affected part, thickness is 2-3mm, upper cover one deck gauze, with the sealing of plastic sheeting adhesive plaster, takes off after 1-2 hour and washs affected part with warm water.
Advantage of the present invention is:
Ointment determined curative effect of the present invention, component are reasonable, and have promoting blood circulation to remove obstruction in the collateral, clearing away damp-heat, except arthralgia pain, improve the effect such as microcirculation, relaxing muscles and tendons regulating menstruation, life-time service is safe and effective, has no side effect.
using method
The lighter applies 1-2 time every day, and severe one applies 2-3 time every day, and within one month, be a course for the treatment of, general 3-4 can cure a course for the treatment of.
Detailed description of the invention
Embodiment 1
Treat an external-applied ointment for old osteoarthritis, it is made up of the raw material of following weight parts (kilogram):
The Radix Rehmanniae 20, Rhizoma Curculiginis 20, Ramulus Mori 20, Radix Aconiti Kusnezoffii Preparata 12, Herba Epimedii 15, Radix Stephaniae Tetrandrae 12, Scorpio 4, Pericarpium Metaplexis 12, Folium Artemisiae Argyi 5, Rhizoma Kaempferiae 7, Resina Ferulae 10, Radix Aconiti Preparata 6, Caulis Piperis Kadsurae 7, Radix Jujubae 4, Cortex Cinnamomi 10, Radix Saposhnikoviae 13, Ramulus Pini 12, Pericarpium Citri Reticulatae 10, Rhizoma Zingiberis Recens 6, Cortex ulmi pumilae 5, Rhizoma Et Radix Notopterygii 10, Radix Paeoniae Rubra 20, Zaocys 15.
Treat a preparation method for the external-applied ointment of old osteoarthritis, comprise the following steps:
(1) add above-mentioned Radix Saposhnikoviae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae by after Mel heated and boiled, low baking temperature infiltrates 15 minutes, takes out and is placed in food steamer, steam 5 minutes at 90 DEG C, and take out, drying grinds into powder; Be covered with one deck bottom described food steamer in vinegar, soak the Folium Crataegi taken out after 10 minutes, the consumption of described Mel is 7% of Radix Saposhnikoviae;
(2) after Oryza glutinosa, Fructus Jujubae being added water and boil, filter, obtain Fructus Jujubae Rice & peanut milk, above-mentioned Rhizoma Curculiginis, Folium Artemisiae Argyi are joined in Fructus Jujubae Rice & peanut milk, add a cover, low baking temperature boils in a covered pot over a slow fire system 10 minutes, take out, drying grinds into powder, and the weight ratio of described Oryza glutinosa and Fructus Jujubae is 10:1, and the amount of reusing of described Fructus Jujubae Rice & peanut milk is 14% of Rhizoma Curculiginis weight;
(3) each for residue raw material is added flooding 4 times, filter cleaner, merging filtrate, concentrate drying, grinds into powder;
(4) by each powder mixing and stirring obtained above, the external-applied ointment of the old osteoarthritis of described treatment is obtained.
Treat an external-applied ointment for old osteoarthritis, this ointment in use, with the Ovum Gallus domesticus album of its quality 60%, 0.3% glycerol mixing and stirring after, be coated on affected part, thickness is 3mm, upper cover one deck gauze, with the sealing of plastic sheeting adhesive plaster, take off after 2 hours and wash affected part with warm water.
model case
example one
Liu, female, 63 years old, extremity size joint congestion and swelling pain when examining, inconvenient activity, joint stuffiness, meet cold increasing the weight of, shallow complexion was simple and unadorned, emaciated physique, uses ointment of the present invention, and subsides in a day two, fully recover after 3 courses for the treatment of, visit, have no recurrence after 1 year.
example two
Wang, man, 68 years old is dancer at an early age, must paint joint osteoarthritis more than 3 years, squat down, stair activity hurt like hell, and use ointment of the present invention, subsides in a day two, fully recover after 4 courses for the treatment of, visit, have no recurrence after 1 year.
example three
Chen, female, 70 years old, when examining, right instep, toes congestion and swelling pain, once took anti-inflammatory drug for a long time, though pain is alleviated sometimes to some extent, but to stand for a long time, the pain such as to walk will aggravate, this female is fat, it is impatient that To Be Protected from Heat, use ointment of the present invention, subsides in a day two, fully recovered after 3 courses for the treatment of, visit after 1 year, have no recurrence.
Claims (2)
1. treat an external-applied ointment for old osteoarthritis, it is characterized in that, crude drug is made up of following medical material:
Radix Rehmanniae 10-20, Rhizoma Curculiginis 10-20, Ramulus Mori 10-20, Radix Aconiti Kusnezoffii Preparata 10-12, Herba Epimedii 10-15, Radix Stephaniae Tetrandrae 10-12, Scorpio 3-4, Pericarpium Metaplexis 10-12, Folium Artemisiae Argyi 5-7, Rhizoma Kaempferiae 5-7, Resina Ferulae 8-10, Radix Aconiti Preparata 6-8, Caulis Piperis Kadsurae 6-7, Radix Jujubae 4-5, Cortex Cinnamomi 9-10, Radix Saposhnikoviae 10-13, Ramulus Pini 10-12, Pericarpium Citri Reticulatae 7-10, Rhizoma Zingiberis Recens 4-6, Cortex ulmi pumilae 3-5, Rhizoma Et Radix Notopterygii 6-10, Radix Paeoniae Rubra 10-20, Zaocys 10-15;
The preparation method of the external-applied ointment of the old osteoarthritis of described treatment, comprises the following steps:
(1) add above-mentioned Radix Saposhnikoviae, Rhizoma Zingiberis Recens, Pericarpium Citri Reticulatae by after Mel heated and boiled, low baking temperature infiltrates 10-15 minute, takes out and is placed in food steamer, steam 3-5 minute at 80-90 DEG C, and take out, drying grinds into powder; Be covered with one deck bottom described food steamer in vinegar, soak the Folium Crataegi taken out after 10-20 minute, the consumption of described Mel is the 5-7% of Radix Saposhnikoviae;
(2) after Oryza glutinosa, Fructus Jujubae being added water and boil, filter, obtain Fructus Jujubae Rice & peanut milk, above-mentioned Rhizoma Curculiginis, Folium Artemisiae Argyi are joined in Fructus Jujubae Rice & peanut milk, add a cover, low baking temperature boils in a covered pot over a slow fire 8-10 minute processed, take out, drying grinds into powder, and the weight ratio of described Oryza glutinosa and Fructus Jujubae is 8-10:1, and the consumption of described Fructus Jujubae Rice & peanut milk is the 10-14% of Rhizoma Curculiginis weight;
(3) each for residue raw material is added flooding 3-4 time, filter cleaner, merging filtrate, concentrate drying, grind into powder;
(4) by each powder mixing and stirring obtained above, the external-applied ointment of the old osteoarthritis of described treatment is obtained.
2. a kind of external-applied ointment for the treatment of old osteoarthritis according to claim 1, it is characterized in that, this ointment in use, after the glycerol mixing and stirring of the Ovum Gallus domesticus album of its quality 50-60%, 0.1-0.3%, be coated on affected part, thickness is 2-3mm, upper cover one deck gauze, with the sealing of plastic sheeting adhesive plaster, take off after 1-2 hour and wash affected part with warm water.
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CN105688048B (en) * | 2016-03-05 | 2020-04-28 | 上海中医药大学附属曙光医院 | Traditional Chinese medicine preparation for treating rheumatoid arthritis |
CN109731132B (en) * | 2019-01-30 | 2021-05-11 | 中国人民解放军西部战区总医院 | Liquid bandage containing rhizoma Zingiberis recens extract for relieving arthralgia |
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CN101700395A (en) * | 2009-11-24 | 2010-05-05 | 张套林 | Ointment for curing hyperosteogeny |
CN102188673A (en) * | 2010-03-17 | 2011-09-21 | 赵贵凤 | Plaster for promoting muscles and bones, and preparation and application thereof |
CN102247585A (en) * | 2010-05-20 | 2011-11-23 | 潘治宇 | Chinese medicinal composition for treating rheumatism, preparation thereof and preparation method thereof |
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CN101637345A (en) * | 2009-06-16 | 2010-02-03 | 成进学 | Microelement far infrared nanofibre textile bedding with functions of body building and life prolonging |
CN101700395A (en) * | 2009-11-24 | 2010-05-05 | 张套林 | Ointment for curing hyperosteogeny |
CN102188673A (en) * | 2010-03-17 | 2011-09-21 | 赵贵凤 | Plaster for promoting muscles and bones, and preparation and application thereof |
CN102247585A (en) * | 2010-05-20 | 2011-11-23 | 潘治宇 | Chinese medicinal composition for treating rheumatism, preparation thereof and preparation method thereof |
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