CN103316321B - Colitis treatment spray - Google Patents

Colitis treatment spray Download PDF

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CN103316321B
CN103316321B CN201310291839.0A CN201310291839A CN103316321B CN 103316321 B CN103316321 B CN 103316321B CN 201310291839 A CN201310291839 A CN 201310291839A CN 103316321 B CN103316321 B CN 103316321B
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parts
spray
colitis
weight
fructus rosae
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CN103316321A (en
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赵彦强
闵建强
赵彦峰
田金玉
赵浩政
赵浩然
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Abstract

A colitis treatment spray comprises 6 parts by weight of dry ginger, 5-7 parts by weight of Semen Euryales, 5-7 parts by weight of Fructus Rosae Laevigatae and 6-8 parts by weight of Agrimonia eupatoria. The spray is convenient to use, can treat the colitis only through spraying the spray on the abdomen, has the advantages of targeted drug delivery, transdermal absorption, external treatment of internal diseases, avoiding of the irradiation to the stomach and the toxic side effects to the liver, no influences on the normal diet habits of patients, no destroy of the digestive juice to the effective components in the spray, avoiding of the effect reduction caused by the first pass effect of the liver, and abdominal distension and abdominal pain mitigation 3-15min after the spraying of the spray on the top of the abdomen, cure after 3-6 months, safety, high efficiency, definite drug effects, and high cure rate, initiates a novel drug application mode, and has the initiativeness.

Description

A kind of spray for the treatment of colitis
Technical field
The invention belongs to Chinese medicine preparation technical field, relate to a kind of spray, particularly a kind of spray for the treatment of colitis.
Background technology
Colitis claims again nonspecific ulcerative colitis, and how slow onset is, and state of an illness weight differs, main clinical manifestation is diarrhoea, abdominal distention, stomachache, Mucous Stool and bloody purulent stool, tenesmus, obstructed stool in constipation, a few days even, time and while diarrhoea and constipation are often weak etc. with becoming thin.Traditional Therapeutic Method is single medication or single antiinflammatory, pain relieving, antidiarrheal, although can respite symptom, but can not prolongedly cure, and oral medication easily produces and stimulates patient's gastrointestinal tract, the first pass effect of liver also can reduce drug effect, and medicine can produce certain toxic and side effects to patient's liver simultaneously.Colitis is shown effect repeatedly, and the diseases such as the easy initiation of obstinate is had blood in stool in a large number, intestinal stenosis, intestinal perforation, toxic dilatation of intestine, colon cancer make patient be absorbed in worry extremely, sorrow, even increase the weight of the state of an illness.
Summary of the invention
Although the object of the invention is for solve the medicine of traditional treatment colitis can respite symptom but can not prolonged healing technical problem, in order to address this problem, we have designed a kind of spray for the treatment of colitis, targeted delivery of drugs, Transdermal absorption, inner disease outer treat, impairment of ZANG FU-organs not, safe and efficient, drug effect is definite, easy to use, can patient's gastrointestinal tract not produced and be stimulated, can not affect patient's dietary habit, effective ingredient in spray can not be subject to the destruction of Digestive system, also can avoid reducing drug effect because of the first pass effect of liver, spray abdominal distention after 3-15 minute, the symptoms such as stomachache alleviate, within 3-6 month, can cure, effective, instant effect, cure rate is high, started a kind of new-type application method, have initiative.
The present invention realizes the concrete technical scheme that goal of the invention adopts to be: a kind of spray for the treatment of colitis, key is: in described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, Semen Euryales 5-7 part, Fructus Rosae Laevigatae 5-7 part, Herba Agrimoniae 6-8 part.
In described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, 5 parts of Semen Euryaless, 5 parts of Fructus Rosae Laevigatae, 6 parts of Herba Agrimoniaes.
In described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, 7 parts of Semen Euryaless, 7 parts of Fructus Rosae Laevigatae, 8 parts of Herba Agrimoniaes.
In described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, 6 parts of Semen Euryaless, 6 parts of Fructus Rosae Laevigatae, 6 parts of Herba Agrimoniaes.
In described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, 7 parts of Semen Euryaless, 5 parts of Fructus Rosae Laevigatae, 7 parts of Herba Agrimoniaes.
In described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, 5 parts of Semen Euryaless, 6 parts of Fructus Rosae Laevigatae, 8 parts of Herba Agrimoniaes.
Described spray is treated colitis by being sprayed on belly.
The invention has the beneficial effects as follows: targeted delivery of drugs, Transdermal absorption, inner disease outer treat, is sprayed on spray on belly after 3-15 minute the symptoms such as abdominal distention, stomachache and alleviates, and within 3-6 month, can cure, and has started a kind of new-type application method, has initiative.Impairment of ZANG FU-organs, not easy to use, can not produce any stimulation to patient's stomach, can not affect patient's dietary habit, the effective ingredient in spray can not be subject to the destruction of Digestive system, can also avoid subtracting effect because of the first pass effect of liver, safe and efficient, drug effect is definite, and cure rate is high.
The property of medicine and the pharmacology of various Chinese medicines of the present invention are respectively:
Rhizoma Zingiberis: acrid in the mouth, hot in nature.Warming spleen and stomach for dispelling cold, recuperating depleted YANG are promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention.
Semen Euryales: sweet in the mouth, property are put down.Nourish strong essence, relieving diarrhea with astringents, calm convergence.
Fructus Rosae Laevigatae: sour in the mouth, sweet, puckery, property are flat.Controlling nocturnal emission with astringent drugs reducing urination, relieving diarrhea with astringents, relieving cough and asthma, anti-inflammation.
Herba Agrimoniae: bitter in the mouth, puckery, property are flat.Hemostasis, anti-inflammation, relieving diarrhea with astringents, parasite killing.
The specific embodiment
A spray for the treatment of colitis, key is: in described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, Semen Euryales 5-7 part, Fructus Rosae Laevigatae 5-7 part, Herba Agrimoniae 6-8 part.
In described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, 5 parts of Semen Euryaless, 5 parts of Fructus Rosae Laevigatae, 6 parts of Herba Agrimoniaes.
In described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, 7 parts of Semen Euryaless, 7 parts of Fructus Rosae Laevigatae, 8 parts of Herba Agrimoniaes.
In described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, 6 parts of Semen Euryaless, 6 parts of Fructus Rosae Laevigatae, 6 parts of Herba Agrimoniaes.
In described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, 7 parts of Semen Euryaless, 5 parts of Fructus Rosae Laevigatae, 7 parts of Herba Agrimoniaes.
In described spray, the part by weight umber of each raw material is: 6 parts of Rhizoma Zingiberiss, 5 parts of Semen Euryaless, 6 parts of Fructus Rosae Laevigatae, 8 parts of Herba Agrimoniaes.
Described spray is treated colitis by being sprayed on belly.
Embodiment 1, Rhizoma Zingiberis 60g, Semen Euryales 50g, Fructus Rosae Laevigatae 50g, Herba Agrimoniae 60g.
Embodiment 2, Rhizoma Zingiberis 60g, Semen Euryales 70g, Fructus Rosae Laevigatae 70g, Herba Agrimoniae 80g.
Embodiment 3, Rhizoma Zingiberis 60g, Semen Euryales 60g, Fructus Rosae Laevigatae 60g, Herba Agrimoniae 60g.
Embodiment 4, Rhizoma Zingiberis 60g, Semen Euryales 70g, Fructus Rosae Laevigatae 50g, Herba Agrimoniae 70g.
Embodiment 5, Rhizoma Zingiberis 60g, Semen Euryales 50g, Fructus Rosae Laevigatae 60g, Herba Agrimoniae 80g.
Preparation method of the present invention is: gets pure water 2500ml, by the weight in above five embodiment, puts into Rhizoma Zingiberis respectively, and Semen Euryales, Fructus Rosae Laevigatae, Herba Agrimoniae, boiled after 10 minutes, poured out medicinal liquid, obtained the first medicinal liquid; Medicinal residues are put into condensing unit cooling rapidly, when medicinal residues reach the freezing point, then pour the first medicinal liquid into, and then boil after 15 minutes, pour out medicinal liquid, obtain the second medicinal liquid; When again medicinal residues being put into condensing unit and being cooled to freezing point rapidly, pour the second medicinal liquid into, then boil after 10 minutes, pour out medicinal liquid, obtain the 3rd medicinal liquid; When the 3rd medicinal liquid is condensed into 1000ml, adds 55 ° from making grain wine 1500ml, then add a small amount of cutaneous permeable agent and get final product.
This spray is sprayed on belly after 3-15 minute the symptoms such as abdominal distention, stomachache and alleviates, and within 3-6 month, can cure.
For showing the therapeutic effect of the present invention to colitis, the inventor suffers from the case of colitis in various degree to 100 examples and carries out clinical observation, male 56 people wherein, women 44 people, age 28-70 year, course of disease 2-14, by spraying spray 3-6 of the present invention month, 90 people cure, and cure rate reaches 90%, 100 people are effective, and effective percentage is 100%.

Claims (7)

1. a spray for the treatment of colitis, is characterized in that: in described spray, the part by weight umber of each raw material of Chinese medicine is: 6 parts of Rhizoma Zingiberiss, Semen Euryales 5-7 part, Fructus Rosae Laevigatae 5-7 part, Herba Agrimoniae 6-8 part.
2. a kind of spray for the treatment of colitis according to claim 1, is characterized in that: in described spray, the part by weight umber of each raw material of Chinese medicine is: 6 parts of Rhizoma Zingiberiss, 5 parts of Semen Euryaless, 5 parts of Fructus Rosae Laevigatae, 6 parts of Herba Agrimoniaes.
3. a kind of spray for the treatment of colitis according to claim 1, is characterized in that: in described spray, the part by weight umber of each raw material of Chinese medicine is: 6 parts of Rhizoma Zingiberiss, 7 parts of Semen Euryaless, 7 parts of Fructus Rosae Laevigatae, 8 parts of Herba Agrimoniaes.
4. a kind of spray for the treatment of colitis according to claim 1, is characterized in that: in described spray, the part by weight umber of each raw material of Chinese medicine is: 6 parts of Rhizoma Zingiberiss, 6 parts of Semen Euryaless, 6 parts of Fructus Rosae Laevigatae, 6 parts of Herba Agrimoniaes.
5. a kind of spray for the treatment of colitis according to claim 1, is characterized in that: in described spray, the part by weight umber of each raw material of Chinese medicine is: 6 parts of Rhizoma Zingiberiss, 7 parts of Semen Euryaless, 5 parts of Fructus Rosae Laevigatae, 7 parts of Herba Agrimoniaes.
6. a kind of spray for the treatment of colitis according to claim 1, is characterized in that: in described spray, the part by weight umber of each raw material of Chinese medicine is: 6 parts of Rhizoma Zingiberiss, 5 parts of Semen Euryaless, 6 parts of Fructus Rosae Laevigatae, 8 parts of Herba Agrimoniaes.
7. according to a kind of spray for the treatment of colitis described in claim 1-6 any one, it is characterized in that: described spray is treated colitis by being sprayed on belly.
CN201310291839.0A 2013-07-12 2013-07-12 Colitis treatment spray Active CN103316321B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101112606A (en) * 2007-07-30 2008-01-30 何伟 Chinese traditional medicine for treating enteritis
CN101703749A (en) * 2009-11-13 2010-05-12 秦中文 Chinese medicament for treating chronic colonitis
CN101829217A (en) * 2010-05-10 2010-09-15 苏开志 Traditional Chinese medicine for treating chronic colitis
CN102302750A (en) * 2011-08-15 2012-01-04 荣成市商贸城卫生所 Traditional Chinese medicine composition for treating chronic enteritis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101112606A (en) * 2007-07-30 2008-01-30 何伟 Chinese traditional medicine for treating enteritis
CN101703749A (en) * 2009-11-13 2010-05-12 秦中文 Chinese medicament for treating chronic colonitis
CN101829217A (en) * 2010-05-10 2010-09-15 苏开志 Traditional Chinese medicine for treating chronic colitis
CN102302750A (en) * 2011-08-15 2012-01-04 荣成市商贸城卫生所 Traditional Chinese medicine composition for treating chronic enteritis

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
中医治疗溃疡性结肠炎研究纂要;韩远茹;《实用中医内科杂志》;20080831;第22卷(第8期);70-72 *
中药保留灌肠治疗溃疡性结肠炎研究进展;彭卓嵛;《河北中医》;20041130;第26卷(第11期);877-879 *
中药肠道给药治疗溃疡性结肠炎的研究进展述评;陈永杰等;《第二届肛肠学术交流会论文集》;20061201;76-88 *
彭卓嵛.中药保留灌肠治疗溃疡性结肠炎研究进展.《河北中医》.2004,第26卷(第11期),877-879.
陈永杰等.中药肠道给药治疗溃疡性结肠炎的研究进展述评.《第二届肛肠学术交流会论文集》.2006,76-88.
韩远茹.中医治疗溃疡性结肠炎研究纂要.《实用中医内科杂志》.2008,第22卷(第8期),70-72.

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