CN103301326A - Medicament for treating rheumatism, rheumatoid and pain or rheumatism in lower extremities and waist - Google Patents
Medicament for treating rheumatism, rheumatoid and pain or rheumatism in lower extremities and waist Download PDFInfo
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- CN103301326A CN103301326A CN2013102333122A CN201310233312A CN103301326A CN 103301326 A CN103301326 A CN 103301326A CN 2013102333122 A CN2013102333122 A CN 2013102333122A CN 201310233312 A CN201310233312 A CN 201310233312A CN 103301326 A CN103301326 A CN 103301326A
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Abstract
The invention relates to a medicament for treating rheumatism, rheumatoid and pain or rheumatism in lower extremities and waist. The medicament comprises the following substances: ginseng, cornua cervi pantotrichum, ginkgo leaf, lucid ganoderma, placenta hominis, notopterygium root, radix angelicae pubescentis, loranthus parasiticus, eucommia ulmoides, teasel root, rhizoma cibotii, large-leaved gentian, achyranthes bidentata, pawpaw, Chinese parsnip root, root of common peony, Chinese angelica, ligusticum wallichii, pseudo-ginseng, long-noded pit viper, gastrodia elata, nux vomica, saffron crocus, keel, oyster, leech, obscured homalomena rhizome, schizophragma integrifolium, garden balsam stem, ant, fructus psoraleae, radix ophiopogonis, dried rehamnnia root, white atractylodes rhizome, poria cocos, white paeony root, radix bupleuri, liquorice, hawthorn and gizzard pepsin. The medicament for treating rheumatism, rheumatoid and pain or rheumatism in lower extremities and waist has the characteristics of being low in cost, easy to prepare, small in toxic and side effect and remarkable in curative effect.
Description
Technical field
The present invention relates to tcm field, specifically, relate to a kind of medicament for the treatment of rheumatism, rheumatoid and waist lower limb arthralgia pain.
Background technology
The rheumatism cause of disease is the human body yin and yang qi and blood disorder, affection of exogenous wind-cold, and pathogen is invaded meridians, the abnormality of healthy energy antagonism pathogen.Pathological changes makes joint swelling deformation, the synovial membrane muscle different pathological changes of extent of injury simultaneously, as untimely treatment, can form chronic destruction of joint, even invades internal organs and bring out other serious diseases, as rheumatic heart disease.
The orthopaedics disease has 5 percent to be because overworked or sprain and cause, with invigorate blood circulation, the method treatment of blood stasis dispelling, pain relieving.But it will be argued that 95 percent is disorder of pectoral QI (doctor trained in Western medicine is called genetic factor and degenerates), the Liver and kidney deficiency of vital energy, stagnation of QI blood stagnation, pathogenic wind-dampness intrusion meridians waist kidney.Symptom has lumbago and skelalgia, numb flaccidity syndrome and arthralgia syndrome, difficulty in walking etc.The doctor trained in Western medicine X-ray is called intervertebral disk hernia, hyperosteogeny, osteoporosis, arthritis etc. after the CT examination, need to use differential diagnosis in tcm to execute and control.Because of prolonged illness must be empty, should nurse one's health pectoral qi, the temperature compensation Liver and kidney, blood circulation promoting and blood stasis dispelling, wind-damp dispelling, the meridian dredging, pain relieving is painful, reinforcement and elimination in combination.
Summary of the invention
The purpose of this invention is to provide a kind of medicament for the treatment of rheumatism, rheumatoid and waist lower limb arthralgia pain.
In order to realize purpose of the present invention, the invention provides a kind of rheumatism for the treatment of, the medicament of rheumatoid and waist lower limb arthralgia pain, it comprises following materials by weight: Radix Ginseng 10-15 part, Cornu Cervi Pantotrichum 2-4 part, Folium Ginkgo 10-15 part, Ganoderma 10-20 part, Placenta Hominis 30-50 part, Rhizoma Et Radix Notopterygii 10-20 part, Radix Angelicae Pubescentis 10-20 part, Herba Taxilli 10-30 part, Cortex Eucommiae 5-20 part, Radix Dipsaci 5-20 part, Rhizoma Cibotii 5-20 part, Radix Gentianae Macrophyllae 10-20 part, Radix Achyranthis Bidentatae 5-20 part, Fructus Chaenomelis 5-20 part, Radix Saposhnikoviae 5-20 part, Radix Paeoniae Rubra 10-20 part, Radix Angelicae Sinensis 5-20 part, Rhizoma Chuanxiong 5-20 part, Radix Notoginseng 1-5 part, Agkistrodon 200-300 part, Rhizoma Gastrodiae 5-20 part, Semen Strychni 1-5 part, Stigma Croci 1-5 part, Os Draconis 20-30 part, Concha Ostreae 20-30 part, Hirudo 30-40 part, Rhizoma Homalomenae 5-20 part, Cortex schizophragmatis integrifolii radicis 5-20 part, Herba speranskiae tuberculatae 5-20 part, Formica fusca 10-20 part, Fructus Psoraleae 1-15 part, Radix Ophiopogonis 10-15 part, Radix Rehmanniae 5-20 part, Rhizoma Atractylodis Macrocephalae 5-20 part, Poria 10-20 part, Radix Paeoniae Alba 5-20 part, Radix Bupleuri 5-20 part, Radix Glycyrrhizae 10-20 part, Fructus Crataegi 5-20 part and Endothelium Corneum Gigeriae Galli 5-20 part.
Preferably, treatment rheumatism of the present invention, the medicament of rheumatoid and waist lower limb arthralgia pain comprises following materials by weight: 10 parts of Radix Ginsengs, 3 parts in Cornu Cervi Pantotrichum, 15 parts of Folium Ginkgos, 15 parts of Ganodermas, 40 parts of Placenta Hominiss, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Radix Angelicae Pubescentiss, 20 parts of Herba Taxillis, 10 parts of the Cortexs Eucommiae, 10 parts of Radix Dipsacis, 10 parts of Rhizoma Cibotii, 15 parts of Radix Gentianae Macrophyllae, 10 parts of Radix Achyranthis Bidentataes, 10 parts of Fructus Chaenomeliss, 10 parts of Radix Saposhnikoviaes, 15 parts of Radix Paeoniae Rubra, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiongs, 3 parts of Radix Notoginseng, 250 parts of Agkistrodons, 10 parts in Rhizoma Gastrodiae, 3 parts of Semen Strychni, 3 parts of Stigma Crocis, 25 parts of Os Draconis, 25 parts of Concha Ostreaes, 35 parts of Hirudos, 10 parts of Rhizoma Homalomenaes, 10 parts of Cortex schizophragmatis integrifolii radicis, 10 parts of Herba speranskiae tuberculataes, 15 parts of Formica fuscas, 10 parts of Fructus Psoraleaes, 10 parts of Radix Ophiopogonis, 10 parts of Radix Rehmanniae, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts in Poria, 10 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 15 parts in Radix Glycyrrhizae, 10 parts of 10 parts of Fructus Crataegis and Endothelium Corneum Gigeriae Galli.
More preferably, the medicament for the treatment of rheumatism of the present invention, rheumatoid and waist lower limb arthralgia pain also comprises following materials by weight: 5 parts of 5 parts of Fructus Broussonetiaes, 6 parts of 3 parts of, Herba Thlaspiss of RADIX PEUCEDANI, 5 parts of Rhizoma Smilacis Chinensiss, 7 parts of Herba Cichoriis, Rhizoma Dioscoreae Septemlobae 46 parts of Fen, Herba Siegesbeckiaes, 3 parts of Herba Gendarussaes, 5 parts of Cortex Syingae Amurensiss, 3 parts of Herba pterocephali, 3 parts of Nodus Nelumbinis Rhizomatis, 7 parts of Medulla Stachyuri (Medulla Helwingiae)s, 4 parts of Flos Bombacis Malabaricis, 5 parts of Concha Arcaes, 3 parts of Caulis Mahoniaes, 6 parts of Folium Sauropis, 7 parts of Semen Lablab Albums, 3 parts of Retinervus Luffae Fructuss, 5 parts of Herba Polygoni cymosis, 3 parts of Semen Celosiae and Fructus Litseae.
More preferably, described medicament can be tablet, dispersible tablet, oral liquid or capsule.
The medicament for the treatment of rheumatism of the present invention, rheumatoid and waist lower limb arthralgia pain has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect is showing.
The specific embodiment
Embodiment 1:
Take by weighing Radix Ginseng 100 grams, Cornu Cervi Pantotrichum 30 grams, Folium Ginkgo 150 grams, Ganoderma 150 grams, Placenta Hominis 400 grams, Rhizoma Et Radix Notopterygii 150 grams, Radix Angelicae Pubescentis 150 grams, Herba Taxilli 200 grams, the Cortex Eucommiae 100 grams, Radix Dipsaci 100 grams, Rhizoma Cibotii 100 grams, Radix Gentianae Macrophyllae 150 grams, Radix Achyranthis Bidentatae 100 grams, Fructus Chaenomelis 100 grams, Radix Saposhnikoviae 100 grams, Radix Paeoniae Rubra 150 grams, Radix Angelicae Sinensis 100 grams, Rhizoma Chuanxiong 100 grams, Radix Notoginseng 30 grams, Agkistrodon 2500 grams, Rhizoma Gastrodiae 100 grams, Semen Strychni 30 grams, Stigma Croci 30 grams, Os Draconis 250 grams, Concha Ostreae 250 grams, Hirudo 350 grams, Rhizoma Homalomenae 100 grams, Cortex schizophragmatis integrifolii radicis 100 grams, Herba speranskiae tuberculatae 100 grams, Formica fusca 150 grams, Fructus Psoraleae 100 grams, restrain Radix Ophiopogonis 100, Radix Rehmanniae 100 grams, the Rhizoma Atractylodis Macrocephalae 100 grams, Poria 150 grams, the Radix Paeoniae Alba 100 grams, Radix Bupleuri 100 grams, Radix Glycyrrhizae 150 grams, Fructus Crataegi 100 grams and Endothelium Corneum Gigeriae Galli 100 grams, add 10000 ml waters, heated 6 hours down at 80 ℃.Filter, it is 1.06 (60 ℃) that filtrate is concentrated into density, is cooled to room temperature, drying.Pulverize, add microcrystalline Cellulose 240 grams, lactose 150 grams and mannitol 200 grams, mix homogeneously is crossed 80 mesh sieves.Then, in spray water, make soft material, cross 20 mesh sieves granulating, drying, granulate namely gets capsule of the present invention in the 100 seed lac softgel shells of packing into.
Embodiment 2:
Take by weighing Radix Ginseng 100 grams, Cornu Cervi Pantotrichum 30 grams, Folium Ginkgo 150 grams, Ganoderma 150 grams, Placenta Hominis 400 grams, Rhizoma Et Radix Notopterygii 150 grams, Radix Angelicae Pubescentis 150 grams, Herba Taxilli 200 grams, the Cortex Eucommiae 100 grams, Radix Dipsaci 100 grams, Rhizoma Cibotii 100 grams, Radix Gentianae Macrophyllae 150 grams, Radix Achyranthis Bidentatae 100 grams, Fructus Chaenomelis 100 grams, Radix Saposhnikoviae 100 grams, Radix Paeoniae Rubra 150 grams, Radix Angelicae Sinensis 100 grams, Rhizoma Chuanxiong 100 grams, Radix Notoginseng 30 grams, Agkistrodon 2500 grams, Rhizoma Gastrodiae 100 grams, Semen Strychni 30 grams, Stigma Croci 30 grams, Os Draconis 250 grams, Concha Ostreae 250 grams, Hirudo 350 grams, Rhizoma Homalomenae 100 grams, Cortex schizophragmatis integrifolii radicis 100 grams, Herba speranskiae tuberculatae 100 grams, Formica fusca 150 grams, Fructus Psoraleae 100 grams, restrain Radix Ophiopogonis 100, Radix Rehmanniae 100 grams, the Rhizoma Atractylodis Macrocephalae 100 grams, Poria 150 grams, the Radix Paeoniae Alba 100 grams, Radix Bupleuri 100 grams, Radix Glycyrrhizae 150 grams, Fructus Crataegi 100 grams, Endothelium Corneum Gigeriae Galli 100 grams, Fructus Broussonetiae 50 grams, RADIX PEUCEDANI 30 gram Herba Thlaspiss 60 grams, Rhizoma Smilacis Chinensis 50 grams, Herba Cichorii 70 gram Rhizoma Dioscoreae Septemlobaes 40 gram Herba Siegesbeckiaes 60 grams, Herba Gendarussae 30 grams, Cortex Syingae Amurensis 50 grams, Herba pterocephali 30 grams, Nodus Nelumbinis Rhizomatis 30 grams, Medulla Stachyuri (Medulla Helwingiae) 70 grams, Flos Bombacis Malabarici 40 grams, Concha Arcae 50 grams, Caulis Mahoniae 30 grams, Folium Sauropi 60 grams, Semen Lablab Album 70 grams, Retinervus Luffae Fructus 30 grams, Herba Polygoni cymosi 50 grams, Semen Celosiae 30 grams and Fructus Litseae 50 grams, add 15000 ml waters, heated 6 hours down at 80 ℃.Filter, it is 1.06 (60 ℃) that filtrate is concentrated into density, is cooled to room temperature, drying.Pulverize, add microcrystalline Cellulose 290 grams, lactose 170 grams and mannitol 250 grams, mix homogeneously is crossed 80 mesh sieves.Then, in spray water, make soft material, cross 20 mesh sieves granulating, drying, granulate namely gets capsule of the present invention in the 100 seed lac softgel shells of packing into.
Experimental example
The equal out-patient treatment of 87 routine patients, male's 23 examples wherein, women's 64 examples; 20-40 year 18 examples; 41-50 year 24 examples; 51-60 year 38 examples, 7 examples more than 60 years old.46 years old mean age; The course of disease average April to 10 year; The sick kind: anemofrigid-damp arthralgia 22 examples, rheumatoid arthritis 12 examples, ankylosing spondylitis 6 examples, neck, shoulder, waist and leg arthralgia pain 47 examples; Differentiation of symptoms and signs for classification of syndrome: cold dampness accumulation pattern 33 examples, Qi deficiency blood stasis type 45 examples, phlegm-damp resistance network type 9 examples.The patient is divided into two groups, first group of 44 routine patient, second group of 43 routine patient, two groups of there was no significant differences (P＞0.05) in side such as sex, age, the course of disease, state of an illness scoring and relatively have comparability.
The capsule of first group of oral embodiment 1 preparation of patient, every day three times, each 2, treating 7 days is 1 course for the treatment of.
The capsule of second group of oral embodiment 2 preparation of patient, every day three times, each 2, treating 7 days is 1 course for the treatment of.
Criterion of therapeutical effect
The criterion of therapeutical effect of formulating with reference to the clinical research guideline of the arthromyodynia of Ministry of Public Health issue and Chinese combination of Chinese and Western medicine rheumatism Professional Committee is also drafted in conjunction with clinical.Cure: clinical symptomatology and sign disappear or basic the disappearance through treating, and the functional activity recovery ends normal, and main physical and chemical index is normal or remarkable to descend; Produce effects: cardinal symptom is eliminated substantially, and main function of joint is recovered substantially or be obviously progressive, and can't take care of oneself becomes and can take care of oneself, and main physical and chemical index makes moderate progress; Invalid: compare before treatment and the treatment, clinical symptoms and sign etc. does not all have obvious improvement.
Therapeutic outcome
Among first group of patient, cure 24 examples, produce effects 20 examples; Among second group of patient, cure 37 examples, produce effects 6 examples.
Claims (4)
1. treat rheumatism for one kind, the medicament of rheumatoid and waist lower limb arthralgia pain is characterized in that it comprises following materials by weight: Radix Ginseng 10-15 part, Cornu Cervi Pantotrichum 2-4 part, Folium Ginkgo 10-15 part, Ganoderma 10-20 part, Placenta Hominis 30-50 part, Rhizoma Et Radix Notopterygii 10-20 part, Radix Angelicae Pubescentis 10-20 part, Herba Taxilli 10-30 part, Cortex Eucommiae 5-20 part, Radix Dipsaci 5-20 part, Rhizoma Cibotii 5-20 part, Radix Gentianae Macrophyllae 10-20 part, Radix Achyranthis Bidentatae 5-20 part, Fructus Chaenomelis 5-20 part, Radix Saposhnikoviae 5-20 part, Radix Paeoniae Rubra 10-20 part, Radix Angelicae Sinensis 5-20 part, Rhizoma Chuanxiong 5-20 part, Radix Notoginseng 1-5 part, Agkistrodon 200-300 part, Rhizoma Gastrodiae 5-20 part, Semen Strychni 1-5 part, Stigma Croci 1-5 part, Os Draconis 20-30 part, Concha Ostreae 20-30 part, Hirudo 30-40 part, Rhizoma Homalomenae 5-20 part, Cortex schizophragmatis integrifolii radicis 5-20 part, Herba speranskiae tuberculatae 5-20 part, Formica fusca 10-20 part, Fructus Psoraleae 1-15 part, Radix Ophiopogonis 10-15 part, Radix Rehmanniae 5-20 part, Rhizoma Atractylodis Macrocephalae 5-20 part, Poria 10-20 part, Radix Paeoniae Alba 5-20 part, Radix Bupleuri 5-20 part, Radix Glycyrrhizae 10-20 part, Fructus Crataegi 5-20 part and Endothelium Corneum Gigeriae Galli 5-20 part.
2. treatment rheumatism according to claim 1, the medicament of rheumatoid and waist lower limb arthralgia pain is characterized in that it comprises following materials by weight: 10 parts of Radix Ginsengs, 3 parts in Cornu Cervi Pantotrichum, 15 parts of Folium Ginkgos, 15 parts of Ganodermas, 40 parts of Placenta Hominiss, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Radix Angelicae Pubescentiss, 20 parts of Herba Taxillis, 10 parts of the Cortexs Eucommiae, 10 parts of Radix Dipsacis, 10 parts of Rhizoma Cibotii, 15 parts of Radix Gentianae Macrophyllae, 10 parts of Radix Achyranthis Bidentataes, 10 parts of Fructus Chaenomeliss, 10 parts of Radix Saposhnikoviaes, 15 parts of Radix Paeoniae Rubra, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiongs, 3 parts of Radix Notoginseng, 250 parts of Agkistrodons, 10 parts in Rhizoma Gastrodiae, 3 parts of Semen Strychni, 3 parts of Stigma Crocis, 25 parts of Os Draconis, 25 parts of Concha Ostreaes, 35 parts of Hirudos, 10 parts of Rhizoma Homalomenaes, 10 parts of Cortex schizophragmatis integrifolii radicis, 10 parts of Herba speranskiae tuberculataes, 15 parts of Formica fuscas, 10 parts of Fructus Psoraleaes, 10 parts of Radix Ophiopogonis, 10 parts of Radix Rehmanniae, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts in Poria, 10 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 15 parts in Radix Glycyrrhizae, 10 parts of 10 parts of Fructus Crataegis and Endothelium Corneum Gigeriae Galli.
3. the medicament for the treatment of rheumatism according to claim 1 and 2, rheumatoid and waist lower limb arthralgia pain is characterized in that also comprising following materials by weight: 5 parts of 5 parts of Fructus Broussonetiaes, 6 parts of 3 parts of, Herba Thlaspiss of RADIX PEUCEDANI, 5 parts of Rhizoma Smilacis Chinensiss, 7 parts of Herba Cichoriis, Rhizoma Dioscoreae Septemlobae 46 parts of Fen, Herba Siegesbeckiaes, 3 parts of Herba Gendarussaes, 5 parts of Cortex Syingae Amurensiss, 3 parts of Herba pterocephali, 3 parts of Nodus Nelumbinis Rhizomatis, 7 parts of Medulla Stachyuri (Medulla Helwingiae)s, 4 parts of Flos Bombacis Malabaricis, 5 parts of Concha Arcaes, 3 parts of Caulis Mahoniaes, 6 parts of Folium Sauropis, 7 parts of Semen Lablab Albums, 3 parts of Retinervus Luffae Fructuss, 5 parts of Herba Polygoni cymosis, 3 parts of Semen Celosiae and Fructus Litseae.
4. according to the medicament of each described treatment rheumatism, rheumatoid and waist lower limb arthralgia pain in the claim 1 to 3, it is characterized in that described medicament can be tablet, dispersible tablet, oral liquid or capsule.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310233312.2A CN103301326B (en) | 2013-06-14 | 2013-06-14 | Medicament for treating rheumatism, rheumatoid and pain or rheumatism in lower extremities and waist |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310233312.2A CN103301326B (en) | 2013-06-14 | 2013-06-14 | Medicament for treating rheumatism, rheumatoid and pain or rheumatism in lower extremities and waist |
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| CN103301326A true CN103301326A (en) | 2013-09-18 |
| CN103301326B CN103301326B (en) | 2014-09-03 |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103585536A (en) * | 2013-12-04 | 2014-02-19 | 刘奕平 | Preparation method of medicine for treating puerperal arthralgia |
| CN103877335A (en) * | 2014-04-19 | 2014-06-25 | 王琴华 | Medicine for curing rheumatoid arthritis and preparation method of medicine |
| CN104056041A (en) * | 2014-07-03 | 2014-09-24 | 朱长怀 | Chinese herb preparation for treating sprains |
| CN105726646A (en) * | 2016-03-08 | 2016-07-06 | 青岛市中心医院 | Medicine composition for treating rheumatoid arthritis through immune adjustment and preparation method of medicine composition |
Citations (1)
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| CN1144688A (en) * | 1996-07-13 | 1997-03-12 | 臧运升 | Medicine for treatment of lumbus and leg paralyses pain |
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2013
- 2013-06-14 CN CN201310233312.2A patent/CN103301326B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1144688A (en) * | 1996-07-13 | 1997-03-12 | 臧运升 | Medicine for treatment of lumbus and leg paralyses pain |
Non-Patent Citations (1)
| Title |
|---|
| 李敏: "中药治疗风湿伤痛的研究进展", 《浙江中西医结合杂志》, vol. 15, no. 4, 31 December 2005 (2005-12-31) * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103585536A (en) * | 2013-12-04 | 2014-02-19 | 刘奕平 | Preparation method of medicine for treating puerperal arthralgia |
| CN103877335A (en) * | 2014-04-19 | 2014-06-25 | 王琴华 | Medicine for curing rheumatoid arthritis and preparation method of medicine |
| CN104056041A (en) * | 2014-07-03 | 2014-09-24 | 朱长怀 | Chinese herb preparation for treating sprains |
| CN105726646A (en) * | 2016-03-08 | 2016-07-06 | 青岛市中心医院 | Medicine composition for treating rheumatoid arthritis through immune adjustment and preparation method of medicine composition |
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| CN103301326B (en) | 2014-09-03 |
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