CN103263682B - A kind of portable room vaporization hydrogen peroxide sterilization system - Google Patents
A kind of portable room vaporization hydrogen peroxide sterilization system Download PDFInfo
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Abstract
Description
技术领域technical field
本发明涉及一种移动式房间汽化过氧化氢灭菌系统。The invention relates to a mobile room vaporized hydrogen peroxide sterilization system.
背景技术Background technique
目前,中国国内药厂洁净厂房的灭菌方式主要以甲醛熏蒸这种传统方式为主,不仅灭菌效果差,还存在对人体具有伤害甚至致癌的风险。这种传统的灭菌方式已经不能满足新版GMP的要求。At present, the traditional method of formaldehyde fumigation is the main method of sterilization for the clean workshops of domestic pharmaceutical factories in China, which not only has poor sterilization effect, but also has the risk of harming the human body and even causing cancer. This traditional sterilization method can no longer meet the requirements of the new GMP.
研究发现,过氧化氢蒸汽具有极强的灭菌能力。过氧化氢蒸汽在灭菌空间内形成微冷凝后将细胞包裹,通过释放的氢氧基对细胞进行多面攻击,包括细胞膜、细胞质以及DNA和RNA,促使微生物彻底失活,从而达到高水平的灭菌,并且对细菌、孢子、真菌、霉菌和病毒都广谱有效。过氧化氢蒸汽具有良好的材料兼容性,对于药厂洁净厂房内绝大多数材料都不会产生影响或腐蚀。同时,过氧化氢蒸汽还具有无残留的特性,通过催化极易分解成水和氧气,使灭菌后的洁净厂房恢复初始状态。因此,合理、有效地控制过氧化氢蒸汽对药厂洁净厂房进行灭菌不仅极大地提高了灭菌能力和效率,而且还起到了对人员和环境的保护。Studies have found that hydrogen peroxide vapor has an extremely strong sterilizing ability. The hydrogen peroxide vapor forms micro-condensation in the sterilization space and wraps the cells, and the released hydroxyl groups attack the cells on multiple sides, including the cell membrane, cytoplasm, DNA and RNA, and promote the complete inactivation of microorganisms, thereby achieving a high level of inactivation. Bacteria and is broad-spectrum effective against bacteria, spores, fungi, molds and viruses. Hydrogen peroxide vapor has good material compatibility, and it will not affect or corrode most of the materials in the clean workshop of the pharmaceutical factory. At the same time, hydrogen peroxide vapor also has the characteristics of no residue, and can be easily decomposed into water and oxygen through catalysis, so that the sterilized clean workshop can be restored to its original state. Therefore, reasonable and effective control of hydrogen peroxide vapor to sterilize the clean workshop of pharmaceutical factories not only greatly improves the sterilization ability and efficiency, but also protects personnel and the environment.
发明内容Contents of the invention
本发明要解决的技术问题是提供一种移动式房间汽化过氧化氢灭菌系统,能够安全可靠地产生过氧化氢蒸汽以进行药厂洁净厂房灭菌,该移动式房间汽化过氧化氢灭菌系统移动灵活、操作简单、运行可靠、灭菌速度快,并且能够实现广谱杀菌。The technical problem to be solved by the present invention is to provide a mobile room vaporized hydrogen peroxide sterilization system, which can safely and reliably generate hydrogen peroxide vapor to sterilize the clean workshop of a pharmaceutical factory. The system is flexible in movement, simple in operation, reliable in operation, fast in sterilization speed, and can realize broad-spectrum sterilization.
为了达到上述目的,本发明的技术方案是提供了一种移动式房间汽化过氧化氢灭菌系统,其特征在于,包括发生器,所述的发生器包括外壳,外壳上设有出风口和进风口,外壳内部经由隔板分为两个部分,第一个部分与出风口相连通,第二个部分与进风口相连通,第一个部分中设有高效过滤器,第二个部分中设有催化分解过滤器、蒸发器和循环风机,循环风机连接风机出风管,风机出风管的出口连接高效过滤器,蒸发器连接过氧化氢吸管的一端,过氧化氢吸管的另一端设于过氧化氢盛放桶内。In order to achieve the above object, the technical solution of the present invention is to provide a mobile room vaporized hydrogen peroxide sterilization system, which is characterized in that it includes a generator, and the generator includes a shell, and the shell is provided with an air outlet and an air inlet. The inside of the shell is divided into two parts through the partition, the first part communicates with the air outlet, the second part communicates with the air inlet, the first part is equipped with a high-efficiency filter, and the second part is equipped with There are catalytic decomposition filter, evaporator and circulation fan, the circulation fan is connected to the fan outlet pipe, the outlet of the fan outlet pipe is connected to the high-efficiency filter, the evaporator is connected to one end of the hydrogen peroxide straw, and the other end of the hydrogen peroxide straw is located on Hydrogen peroxide is stored in barrels.
优选地,所述的外壳内的第二个部分中还设有分解室、汽化室以及可移动到气化侧位置和分解侧位置的功能切换挡板,蒸发器设于汽化室中,所述的进风口共有两个,分别是分解进风口和汽化进风口,汽化进风口与汽化室连通,催化分解过滤器设于分解室内,分解进风口与分解室连通,汽化室侧壁上设有汽化侧位置检测装置,分解室侧壁上设有分解侧位置检测装置,功能切换挡板的一端连接发生器框架,另一端连接电动推杆,电动推杆的另一端连接发生器框架,所述的外壳上还设有过氧化氢浓度传感器和过氧化氢放置室,过氧化氢盛放桶设于电子称上,过氧化氢盛放桶和电子称设于过氧化氢放置室内,过氧化氢吸管与蒸发器之间的管路上设有蠕动泵。Preferably, a decomposition chamber, a vaporization chamber, and a function switching baffle that can move to the gasification side position and the decomposition side position are also provided in the second part of the housing, and the evaporator is arranged in the vaporization chamber. There are two air inlets, namely the decomposition air inlet and the vaporization air inlet. The vaporization air inlet is connected to the vaporization chamber. The catalytic decomposition filter is installed in the decomposition chamber. The decomposition air inlet is connected to the decomposition chamber. Side position detection device, the side wall of the decomposition chamber is equipped with a decomposition side position detection device, one end of the function switching baffle is connected to the generator frame, the other end is connected to the electric push rod, and the other end of the electric push rod is connected to the generator frame. The shell is also equipped with a hydrogen peroxide concentration sensor and a hydrogen peroxide storage room, the hydrogen peroxide storage barrel is set on the electronic scale, the hydrogen peroxide storage bucket and the electronic scale are located in the hydrogen peroxide storage room, and the hydrogen peroxide straw A peristaltic pump is provided on the pipeline between the evaporator and the evaporator.
更优选地,所述的外壳包括发生器框架以及分别设于发生器框架前侧、后侧、左侧和右侧的前盖板、后盖板、左盖板和右盖板,分解进风口设于前盖板上,汽化进风口设于后盖板上,过氧化氢浓度传感器设于左盖板上,过氧化氢放置室设于右盖板上,发生器框架的下侧设有发生器脚轮,所述的左盖板上还设有电源、发生器数据线接口以及网口,所述的前盖板上还设有发生器把手,所述的左盖板上还设有打印室门合页,打印室门合页连接打印室门,打印室门上设有发生器门锁。More preferably, the housing includes a generator frame and a front cover, a rear cover, a left cover and a right cover respectively arranged on the front side, the rear side, the left side and the right side of the generator frame, and the air inlet is decomposed It is set on the front cover, the vaporization air inlet is set on the rear cover, the hydrogen peroxide concentration sensor is set on the left cover, the hydrogen peroxide storage chamber is set on the right cover, and the generator frame is installed under the generator frame. generator casters, the left cover is also provided with power supply, generator data line interface and network port, the front cover is also provided with a generator handle, and the left cover is also provided with a printing room The door hinge, the printing chamber door hinge is connected to the printing chamber door, and the generator door lock is arranged on the printing chamber door.
更优选地,所述的高效过滤器设于高效过滤器支架上。More preferably, the high-efficiency filter is arranged on the high-efficiency filter bracket.
更优选地,所述的蒸发器内设有温度探头。More preferably, a temperature probe is provided inside the evaporator.
更优选地,所述的外壳内还设有小型减速机,小型减速机通过联轴器与转轴连接,转轴连接出风口定位挡块,出风口定位挡块设于出风口定位轴上,出风口定位轴固定在出风口上。More preferably, a small speed reducer is also provided in the housing, the small speed reducer is connected to the rotating shaft through a coupling, the rotating shaft is connected to the air outlet positioning stopper, the air outlet positioning stopper is arranged on the air outlet positioning shaft, and the air outlet The positioning shaft is fixed on the air outlet.
更优选地,所述的移动式房间汽化过氧化氢灭菌系统还包括控制器,所述的控制器包括控制器框架,控制器框架内设有控制器,控制器框架上设有触摸屏、急停按钮和控制器数据线接口,触摸屏、急停按钮和控制器数据线接口连接控制器,数据线的一端连接控制器数据线接口,数据线的另一端连接发生器数据线接口,发生器数据线接口设于发生器框架的侧面的盖板上,控制器经由所述的数据线连接电动推杆、过氧化氢浓度传感器、蠕动泵、蒸发器和循环风机。More preferably, the mobile room vaporized hydrogen peroxide sterilization system also includes a controller, the controller includes a controller frame, a controller is arranged in the controller frame, a touch screen, emergency The stop button and the controller data line interface, the touch screen, the emergency stop button and the controller data line interface are connected to the controller, one end of the data line is connected to the controller data line interface, the other end of the data line is connected to the generator data line interface, the generator data The line interface is arranged on the cover plate at the side of the generator frame, and the controller is connected with the electric push rod, the hydrogen peroxide concentration sensor, the peristaltic pump, the evaporator and the circulating fan through the data line.
更优选地,所述的控制器框架上侧设有控制器把手,控制器框架下侧设有控制器脚轮,控制器框架前侧设有控制器合页,控制器合页连接控制器维修门,控制器维修门上设有控制器门锁。More preferably, a controller handle is provided on the upper side of the controller frame, controller casters are provided on the lower side of the controller frame, and a controller hinge is provided on the front side of the controller frame, and the controller hinge is connected to the controller maintenance door. , There is a controller door lock on the controller maintenance door.
本发明的移动式房间汽化过氧化氢灭菌系统,与现有药厂洁净厂房灭菌方式相比具有如下有益效果:本发明采用双循环控制方式,整个灭菌过程可监控,移动灵活,操作合理、简单,运行可靠、成本低,灭菌速度快,并且能够实现广谱杀菌,极大地提高了灭菌能力和效率,而且还起到了对人员和环境的保护。The mobile room vaporized hydrogen peroxide sterilization system of the present invention has the following beneficial effects compared with the existing pharmaceutical factory clean room sterilization methods: the present invention adopts a double-cycle control method, the entire sterilization process can be monitored, the movement is flexible, and the operation It is reasonable, simple, reliable in operation, low in cost, fast in sterilization speed, and can achieve broad-spectrum sterilization, which greatly improves the sterilization ability and efficiency, and also protects personnel and the environment.
附图说明Description of drawings
图1A为本发明实施例发生器外观结构正面布局示意图;Figure 1A is a schematic diagram of the front layout of the appearance structure of the generator according to the embodiment of the present invention;
图1B为本发明实施例发生器外观结构后面布局示意图;Fig. 1B is a schematic diagram of the rear layout of the appearance structure of the generator according to the embodiment of the present invention;
图1C为本发明实施例发生器外观结构左侧布局示意图;Figure 1C is a schematic diagram of the layout on the left side of the appearance structure of the generator according to the embodiment of the present invention;
图1D为本发明实施例发生器外观结构右侧布局示意图;Figure 1D is a schematic diagram of the layout on the right side of the appearance structure of the generator according to the embodiment of the present invention;
图2为本发明实施例发生器内部结构布局示意图;Fig. 2 is a schematic diagram of the internal structure layout of the generator according to the embodiment of the present invention;
图3A为本发明实施例控制器外观结构正面布局示意图;Fig. 3A is a schematic diagram of the front layout of the appearance structure of the controller according to the embodiment of the present invention;
图3B为本发明实施例控制器外观结构侧面布局示意图;Fig. 3B is a schematic diagram of the side layout of the appearance structure of the controller according to the embodiment of the present invention;
图4为本发明实施例各组成单元连接示意图。Fig. 4 is a schematic diagram of connection of each component unit in the embodiment of the present invention.
具体实施方式detailed description
为使本发明更明显易懂,兹以优选实施例,并配合附图作详细说明如下。In order to make the present invention more comprehensible, preferred embodiments are described in detail below with accompanying drawings.
实施例Example
本发明的移动式房间汽化过氧化氢灭菌系统包括发生器和控制器,所述的发生器包括外壳,所述的外壳包括发生器框架12以及分别安装于发生器框架12前侧、后侧、左侧和右侧的前盖板28、后盖板30、左盖板29和右盖板31,发生器框架12上侧安装出风口11,发生器框架12下侧安装发生器脚轮15,如图1A所示,前盖板28上设有分解进风口16和发生器把手17,如图1B所示,后盖板30上设有汽化进风口23,如图1C所示,左盖板29上安装过氧化氢浓度传感器10、电源22、发生器数据线接口14、网口21以及打印室门合页19,打印室门合页19连接打印室门20,打印室门20上安装有发生器门锁13,如图1D所示,右盖板31上设有过氧化氢放置室24,过氧化氢盛放桶26设于电子称27上,过氧化氢盛放桶26和电子称27设于过氧化氢放置室24内,蒸发器49连接过氧化氢吸管25的一端,过氧化氢吸管25的另一端设于过氧化氢盛放桶26内,过氧化氢吸管25与蒸发器49之间的管路上设有蠕动泵50。蒸发器49内设有温度探头51。The mobile room vaporized hydrogen peroxide sterilization system of the present invention includes a generator and a controller, the generator includes a housing, and the housing includes a generator frame 12 and is installed on the front side and the rear side of the generator frame 12 respectively. , front cover plate 28, rear cover plate 30, left cover plate 29 and right cover plate 31 on the left and right sides, air outlet 11 is installed on the generator frame 12 upper side, generator caster 15 is installed on the generator frame 12 lower side, As shown in Figure 1A, the front cover 28 is provided with a decomposition air inlet 16 and a generator handle 17, as shown in Figure 1B, the rear cover 30 is provided with a vaporization air inlet 23, as shown in Figure 1C, the left cover Hydrogen peroxide concentration sensor 10, power supply 22, generator data line interface 14, network port 21 and printing chamber door hinge 19 are installed on 29, and printing chamber door hinge 19 connects printing chamber door 20, and printing chamber door 20 is installed with Generator door lock 13, as shown in Figure 1D, is provided with hydrogen peroxide placement chamber 24 on the right cover plate 31, and hydrogen peroxide holding barrel 26 is located on electronic scale 27, and hydrogen peroxide holding barrel 26 and electronic scale 27 is located in the hydrogen peroxide placement chamber 24, the evaporator 49 connects one end of the hydrogen peroxide suction pipe 25, and the other end of the hydrogen peroxide suction pipe 25 is located in the hydrogen peroxide holding barrel 26, and the hydrogen peroxide suction pipe 25 and the evaporator The pipeline between 49 is provided with peristaltic pump 50. The evaporator 49 is provided with a temperature probe 51 .
如图2所示,外壳内部经由隔板42分为两个部分,隔板42安装在发生器框架12上,第一个部分与出风口11相连通,第二个部分与进风口相连通,第一个部分中设有高效过滤器32和高效过滤器支架33,高效过滤器支架33安装在隔板42上,高效过滤器32设于高效过滤器支架33上。第二个部分中设有催化分解过滤器38、蒸发器49和循环风机45,循环风机45上固定在发生器框架12上,循环风机45连接风机出风管34,风机出风管34的出口连接高效过滤器32,第二个部分中还设有分解室37、汽化室48以及可移动到气化侧位置和分解侧位置的功能切换挡板46,分解室37、汽化室48安装于发生器框架12上,蒸发器49设于汽化室48中,催化分解过滤器38设于分解室37内,汽化进风口23与汽化室48连通,分解进风口16与分解室37连通,分汽化室48侧壁上设有汽化侧位置检测装置47,分解室37侧壁上设有分解侧位置检测装置36,功能切换挡板46的一端连接发生器框架12,另一端连接电动推杆35,电动推杆35的另一端连接发生器框架12,所述的发生器框架12上安装有小型减速机44,小型减速机44通过联轴器43与转轴41连接,转轴41连接出风口定位挡块40,出风口定位挡块40设于出风口定位轴39上,出风口定位轴39固定在出风口11上。As shown in Figure 2, the inside of the shell is divided into two parts via a partition 42, the partition 42 is installed on the generator frame 12, the first part communicates with the air outlet 11, and the second part communicates with the air inlet, The first part is provided with a high-efficiency filter 32 and a high-efficiency filter support 33 , the high-efficiency filter support 33 is installed on the partition 42 , and the high-efficiency filter 32 is located on the high-efficiency filter support 33 . The second part is provided with a catalytic decomposition filter 38, an evaporator 49 and a circulation fan 45, the circulation fan 45 is fixed on the generator frame 12, the circulation fan 45 is connected to the fan outlet pipe 34, and the outlet of the fan outlet pipe 34 Connect high-efficiency filter 32, also be provided with decomposition chamber 37, vaporization chamber 48 and the function switching damper 46 that can move to gasification side position and decomposition side position in the second part, decomposition chamber 37, vaporization chamber 48 are installed in On the device frame 12, the evaporator 49 is arranged in the vaporization chamber 48, the catalytic decomposition filter 38 is arranged in the decomposition chamber 37, the vaporization air inlet 23 is communicated with the vaporization chamber 48, the decomposition air inlet 16 is communicated with the decomposition chamber 37, and the vaporization chamber 48 side walls are provided with a vaporization side position detection device 47, decomposition chamber 37 side walls are provided with a decomposition side position detection device 36, one end of the function switch baffle 46 is connected to the generator frame 12, and the other end is connected to an electric push rod 35. The other end of the push rod 35 is connected to the generator frame 12, and a small speed reducer 44 is installed on the generator frame 12. The small speed reducer 44 is connected to the rotating shaft 41 through a coupling 43, and the rotating shaft 41 is connected to the air outlet positioning block 40 , The air outlet positioning block 40 is arranged on the air outlet positioning shaft 39, and the air outlet positioning shaft 39 is fixed on the air outlet 11.
如图3A和图3B所示,所述的控制器包括控制器框架7,控制器框架7内设有控制器,控制器框架7上侧安装控制器把手1、急停按钮2和安装触摸屏3,控制器框架7前侧安装控制器合页4,控制器合页4连接控制器维修门5,控制器维修门5上装有控制器门锁8。控制器框架7后侧设有控制器数据线接口9,控制器框架7下侧设有控制器脚轮6,触摸屏3、急停按钮2和控制器数据线接口9连接控制器,数据线的一端连接控制器数据线接口9,数据线的另一端连接发生器数据线接口14,控制器经由所述的数据线连接电动推杆35、过氧化氢浓度传感器10、蠕动泵50、蒸发器49、循环风机45和小型减速机44。As shown in Figure 3A and Figure 3B, described controller comprises controller frame 7, is provided with controller in controller frame 7, controller handle 1, emergency stop button 2 and touch screen 3 are installed on the controller frame 7 upper side , controller frame 7 front side installation controller hinge 4, controller hinge 4 connects controller maintenance door 5, controller door lock 8 is housed on the controller maintenance door 5. Controller frame 7 rear side is provided with controller data line interface 9, controller frame 7 lower side is provided with controller caster 6, touch screen 3, emergency stop button 2 and controller data line interface 9 connect controller, one end of data line Connect the controller data line interface 9, the other end of the data line is connected to the generator data line interface 14, and the controller is connected to the electric push rod 35, hydrogen peroxide concentration sensor 10, peristaltic pump 50, evaporator 49, Circulation fan 45 and small speed reducer 44.
如图4所示,工作时分为汽化和分解两个过程,①汽化时:控制器控制电动推杆35将功能切换挡板46拉到分解侧位置检测装置36处,分解侧位置检测装置36检测到功能切换挡板46到达指定位置后,电动推杆35停止工作并保持现有位置,同时控制器控制蠕动泵50工作,将过氧化氢盛放桶26内的过氧化氢通过过氧化氢吸管25泵送到蒸发器49,控制器控制蒸发器49加热并且通过温度探头51检测加热温度,电子称27计量过氧化氢盛放桶26内的过氧化氢剩余液体。同时,循环风机45工作,带动气流流动,使房间内的空气从汽化进风口23进入,使过氧化氢蒸汽从出风口11喷出。此时,小型减速机44带动出风口11转动。当过氧化氢浓度传感器10所检测到的过氧化氢浓度超过设定值时,控制器控制蠕动泵50和蒸发器49停止工作。②分解时:控制器控制电动推杆35将功能切换挡板46推到汽化侧位置检测装置47处,汽化侧位置检测装置47检测到功能切换挡板46到达指定位置后,电动推杆35停止工作并保持现有位置,控制器控制蠕动泵50以及蒸发器49停止加热,同时控制器控制循环风机45继续工作,带动气流流动,使房间内的空气从分解进风口16进入,从出风口11喷出。此时,小型减速机44带动出风口11转动。As shown in Figure 4, the work is divided into two processes of vaporization and decomposition. ① During vaporization: the controller controls the electric push rod 35 to pull the function switching baffle 46 to the position detection device 36 on the decomposition side, and the position detection device 36 on the decomposition side detects After the function switching baffle plate 46 reaches the designated position, the electric push rod 35 stops working and keeps the existing position, and the controller controls the peristaltic pump 50 to work at the same time, and the hydrogen peroxide in the hydrogen peroxide storage barrel 26 is passed through the hydrogen peroxide suction pipe 25 is pumped to the evaporator 49, the controller controls the heating of the evaporator 49 and detects the heating temperature through the temperature probe 51, and the electronic scale 27 measures the residual hydrogen peroxide liquid in the hydrogen peroxide storage barrel 26. Simultaneously, the circulating fan 45 works to drive the air flow, so that the air in the room enters from the vaporization air inlet 23, and the hydrogen peroxide vapor is ejected from the air outlet 11. At this time, the small speed reducer 44 drives the air outlet 11 to rotate. When the hydrogen peroxide concentration detected by the hydrogen peroxide concentration sensor 10 exceeds the set value, the controller controls the peristaltic pump 50 and the evaporator 49 to stop working. ②When decomposing: the controller controls the electric push rod 35 to push the function switch baffle 46 to the position detection device 47 on the vaporization side. After the position detection device 47 on the vaporization side detects that the function switch baffle 46 reaches the designated position, the electric push rod 35 stops Work and maintain the current position, the controller controls the peristaltic pump 50 and the evaporator 49 to stop heating, and the controller controls the circulating fan 45 to continue to work, to drive the air flow, so that the air in the room enters from the decomposition air inlet 16 and flows through the air outlet 11 squirt. At this time, the small speed reducer 44 drives the air outlet 11 to rotate.
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| CN103463663A (en) * | 2013-09-25 | 2013-12-25 | 杭州盈天科学仪器有限公司 | Vaporized hydrogen peroxide sterilizer |
| CN106075510B (en) * | 2016-08-02 | 2022-04-01 | 湖北荷普药业股份有限公司 | Gas sterilization equipment |
| CN107185015A (en) * | 2017-06-29 | 2017-09-22 | 唐长林 | A kind of beverage filling room sterilizing unit and its method |
| CN112858565B (en) * | 2020-12-29 | 2023-02-14 | 上海东富龙爱瑞思科技有限公司 | Multifunctional catalytic decomposition test platform |
| EP4397324A1 (en) * | 2023-01-04 | 2024-07-10 | Halton OY | Decontamination system having a modular decontamination unit |
| EP4397325A1 (en) * | 2023-01-04 | 2024-07-10 | Halton OY | Decontamination unit and method for decontaminating a space |
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