CN103254147B - A kind of preparation method of D-Su-Type-2--(dichloromethyl)-4,5-dihydro-5-[p-(methylsulfonyl) phenyl]-4-oxazole methyl alcohol - Google Patents
A kind of preparation method of D-Su-Type-2--(dichloromethyl)-4,5-dihydro-5-[p-(methylsulfonyl) phenyl]-4-oxazole methyl alcohol Download PDFInfo
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- CN103254147B CN103254147B CN201310137654.4A CN201310137654A CN103254147B CN 103254147 B CN103254147 B CN 103254147B CN 201310137654 A CN201310137654 A CN 201310137654A CN 103254147 B CN103254147 B CN 103254147B
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CN201310137654.4A CN103254147B (en) | 2013-04-19 | 2013-04-19 | A kind of preparation method of D-Su-Type-2--(dichloromethyl)-4,5-dihydro-5-[p-(methylsulfonyl) phenyl]-4-oxazole methyl alcohol |
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CN201310137654.4A CN103254147B (en) | 2013-04-19 | 2013-04-19 | A kind of preparation method of D-Su-Type-2--(dichloromethyl)-4,5-dihydro-5-[p-(methylsulfonyl) phenyl]-4-oxazole methyl alcohol |
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CN103254147A CN103254147A (en) | 2013-08-21 |
CN103254147B true CN103254147B (en) | 2016-04-06 |
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CN103570638A (en) * | 2013-11-07 | 2014-02-12 | 湖北中牧安达药业有限公司 | Synthetic method of florfenicol intermediate cyclic product |
CN106278964B (en) * | 2016-07-31 | 2018-01-16 | 浙江润康药业有限公司 | The preparation method of Florfenicol |
CN108329240B (en) * | 2018-03-27 | 2020-06-26 | 深圳蓝新科技有限公司 | Preparation method of florfenicol intermediate |
CN113402475A (en) * | 2021-06-07 | 2021-09-17 | 山东国邦药业有限公司 | Preparation method of florfenicol intermediate |
CN116041271A (en) * | 2022-12-29 | 2023-05-02 | 山东微研生物科技有限公司 | Preparation method of florfenicol intermediate |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1233244A (en) * | 1996-08-19 | 1999-10-27 | 先灵公司 | Process for preparing intermediates to florfenicol |
CN101812000A (en) * | 2009-11-10 | 2010-08-25 | 张家港市恒盛药用化学有限公司 | Preparation method of thiamphenicol |
CN102131772A (en) * | 2008-07-30 | 2011-07-20 | 英特威国际有限公司 | Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol |
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1233244A (en) * | 1996-08-19 | 1999-10-27 | 先灵公司 | Process for preparing intermediates to florfenicol |
CN102131772A (en) * | 2008-07-30 | 2011-07-20 | 英特威国际有限公司 | Process for preparing oxazoline-protected aminodiol compounds useful as intermediates to florfenicol |
CN101812000A (en) * | 2009-11-10 | 2010-08-25 | 张家港市恒盛药用化学有限公司 | Preparation method of thiamphenicol |
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Inventor after: Li Guoneng Inventor after: Zhang Zhiguo Inventor after: Zhang Weilue Inventor after: Chen Shuai Inventor after: Wang Jiuyan Inventor before: Zhang Zhiguo Inventor before: Zhang Weilue Inventor before: Chen Shuai Inventor before: Wang Jiuyan |
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Effective date of registration: 20180110 Address after: 431800 Jingshan Economic Development Zone, Hubei province people's road, Jingmen Patentee after: Jingshan Ruisheng Pharmaceutical Co., Ltd. Address before: 310023 Hangzhou Province, Zhejiang Province, and road, No. 318 Co-patentee before: Jingshan Ruisheng Pharmaceutical Co., Ltd. Patentee before: Zhejiang University of Science and Technology |