CN103211984A - Medicinal composition for treating chronic rhinitis and preparation method thereof - Google Patents

Medicinal composition for treating chronic rhinitis and preparation method thereof Download PDF

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Publication number
CN103211984A
CN103211984A CN2013101604199A CN201310160419A CN103211984A CN 103211984 A CN103211984 A CN 103211984A CN 2013101604199 A CN2013101604199 A CN 2013101604199A CN 201310160419 A CN201310160419 A CN 201310160419A CN 103211984 A CN103211984 A CN 103211984A
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parts
herba
rhizoma
chronic rhinitis
medicine
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陈宁
王淑静
宋冬雪
凌娜
汲晨锋
徐昶儒
宋辉
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Harbin University of Commerce
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Harbin University of Commerce
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Abstract

The invention discloses a medicinal composition for treating chronic rhinitis. The medicinal composition mainly comprises the following components in parts by weight: 5 to 20 parts of gastrodia tuber, 25 to 35 parts of cocklebur fruit, 4 to 16 parts of mint, 5 to 20 parts of stiff silkworm, 4 to 16 parts of agastache rugosus, 4 to 16 parts of magnolia flower, 10 to 30 parts of Shuanggou, 2 to 10 parts of asarum sieboldi mig, 4 to 16 parts of periostracum cicada, 10 to 25 parts of pinellia ternate, 15 to 30 parts of radix angelicae, 12 to 25 parts of ligusticum sinense oliver, 5 to 15 parts of chrysanthemum, 5 to 15 parts of angelica, 1 to 5 parts of polygala root, 15 to 25 parts of Szechuan lovage rhizome, 12 to 25 parts of radix aucklandiae, 10 to 25 parts of Quinoa, 1 to 5 parts of pericarpium citri reticulatae and 10 to 25 parts of magnolia obavata. The medicinal composition can significantly enhance the phenomena of nasal cavity and nasopharynx mucous membrane hyperaemia, edema and the like, reduces purulent secretion, has the advantages of small toxic or side effect, low cost and the like, and can be widely used as a Chinese medicament for treating the chronic rhinitis.

Description

A kind of pharmaceutical composition for the treatment of chronic rhinitis and preparation method thereof
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of chronic rhinitis, relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment chronic rhinitis of crude drug with the Chinese herbal medicine.
Background technology
Chronic rhinitis (comprising chronic simple rhinitis and chronic simple hypertrophic rhinitis) is one of hals,Nasen und Ohrenheilkunde control emphasis, and along with environmental pollution is serious day by day, morbidity crowd quantity also rises year by year.Because the cause of disease that paathogenic factor is a lot of and definite is not bright, so modern medicine treatment primary disease does not still have ideal etiological treatment medicine based on local symptomatic treatment.Operation and hormone medicine are the present therapeutic schemes that more effectively suppresses disease relapse, but its medical expense height, and it is big to take the amcinonide toxic and side effects for a long time, and the patient with operation postoperative had higher recurrent rate in 1 year.
Summary of the invention
Technical problem to be solved by this invention is to overcome above-described defective, and a kind of pharmaceutical composition of evident in efficacy, with low cost, treatment chronic rhinitis that toxic and side effects is little is provided.Technical problem to be solved by this invention realizes by following technological approaches: a kind of pharmaceutical composition for the treatment of chronic rhinitis, mainly form: 5 ~ 20 parts in Rhizoma Gastrodiae by the component of following weight portion, 25 ~ 35 parts of Fructus Xanthii, 4 ~ 16 parts of Herba Menthaes, 5 ~ 20 parts of Bombyx Batryticatus, 4 ~ 16 parts of Herba Pogostemoniss, 4 ~ 16 parts of Flos Magnoliaes, twoly collude 10 ~ 30 parts, 2 ~ 10 parts of Herba Asaris, 4 ~ 16 parts of Periostracum Cicadaes, 10 ~ 25 parts of the Rhizoma Pinelliaes, 15 ~ 30 parts of the Radixs Angelicae Dahuricae, 12 ~ 25 parts of Rhizoma Ligustici, 5 ~ 15 parts of Flos Chrysanthemis, 5 ~ 15 parts of river Qiang, 1 ~ 5 part of Radix Polygalae, 15 ~ 25 parts of Rhizoma Chuanxiongs, 12 ~ 25 parts of the Radix Aucklandiae, 10 ~ 25 parts of ground Herba chenopodiis, 1 ~ 5 part of Pericarpium Citri Reticulatae, 10 ~ 25 parts of Cortex Magnoliae Officinalis.Be preferably: 12 parts in Rhizoma Gastrodiae, 30 parts of Fructus Xanthii, 10 parts of Herba Menthaes, 12 parts of Bombyx Batryticatus, 10 parts of Herba Pogostemoniss, 10 parts of Flos Magnoliaes, two collude 20 parts, 4 parts of Herba Asaris, 10 parts of Periostracum Cicadaes, 18 parts of the Rhizoma Pinelliaes, 20 parts of the Radixs Angelicae Dahuricae, 18 parts of Rhizoma Ligustici, 10 parts of Flos Chrysanthemis, 10 parts of river Qiang, 1 part of Radix Polygalae, 18 parts of Rhizoma Chuanxiongs, 20 parts of the Radix Aucklandiae, 20 parts of Herba chenopodiis, 2 parts of Pericarpium Citri Reticulataes, 18 parts of Cortex Magnoliae Officinalis.
Aforementioned pharmaceutical compositions of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Pharmaceutical composition of the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese medicine chronic rhinitis, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, filter out the natural plant of awakening consciousness, preventing phlegm from forming and stopping coughing, heat-clearing and toxic substances removing, suppressing the hyperactive liver to relieve the wind syndrome, resolving toxin and disinhibiting the throat, promoting the circulation of QI to relieve pain, according to the theory of Chinese medical science prescription, be prepared from according to certain weight proportion.
The used herbal raw material of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and consumption: dosage of the present invention depends on concrete dosage form, factors such as patient's age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 3~6 every day three times at every turn, every content of dispersion 0.3g, warm water takes.2) tablet: obey 3~6 every day three times at every turn, every content of dispersion 0.3g, warm water takes.3) pill: obey 8g every day three times, warm water takes at every turn.
The present invention is directed to chronic rhinitis patient rhinitis relapse rate height, long characteristics of cycle, filter out and medicablely can reduce relapse rate, the crude drug of mitigation symptoms, very effective in cure to nasal obstruction, syncope due to accumulation of phlegm QI rising in reverse order, chest and diaphragm distension, dizzy sleeplessness, various crude drug are coordinated can farthest bring into play drug effect mutually together, can effectively improve patient's body oneself healing ability, can significantly improve phenomenons such as patient's nasal cavity and the hyperemia of nasopharynx mucosa, edema, reduce purulent secretion, have advantages such as toxic and side effects is little, expense is cheap in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never limit the scope of the invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight: Rhizoma Gastrodiae 12g, Fructus Xanthii 30g, Herba Menthae 10g, Bombyx Batryticatus 12g, Herba Pogostemonis 10g, Flos Magnoliae 10g, two 20g of colluding, Herba Asari 4g, Periostracum Cicadae 10g, Rhizoma Pinelliae 18g, Radix Angelicae Dahuricae 20g, Rhizoma Ligustici 18g, Flos Chrysanthemi 10g, the 10g of river Qiang, Radix Polygalae 1g, Rhizoma Chuanxiong 18g, Radix Aucklandiae 20g, Herba chenopodii 20g, Pericarpium Citri Reticulatae 2g, Cortex Magnoliae Officinalis 18g.Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight: Rhizoma Gastrodiae 12g, Fructus Xanthii 30g, Herba Menthae 10g, Bombyx Batryticatus 12g, Herba Pogostemonis 10g, Flos Magnoliae 10g, two 20g of colluding, Herba Asari 4g, Periostracum Cicadae 10g, Rhizoma Pinelliae 18g, Radix Angelicae Dahuricae 20g, Rhizoma Ligustici 18g, Flos Chrysanthemi 10g, the 10g of river Qiang, Radix Polygalae 1g, Rhizoma Chuanxiong 18g, Radix Aucklandiae 20g, Herba chenopodii 20g, Pericarpium Citri Reticulatae 2g, Cortex Magnoliae Officinalis 18g.Each raw material of above-mentioned weight is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and make filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material by following weight: Rhizoma Gastrodiae 12g, Fructus Xanthii 30g, Herba Menthae 10g, Bombyx Batryticatus 12g, Herba Pogostemonis 10g, Flos Magnoliae 10g, two 20g of colluding, Herba Asari 4g, Periostracum Cicadae 10g, Rhizoma Pinelliae 18g, Radix Angelicae Dahuricae 20g, Rhizoma Ligustici 18g, Flos Chrysanthemi 10g, the 10g of river Qiang, Radix Polygalae 1g, Rhizoma Chuanxiong 18g, Radix Aucklandiae 20g, Herba chenopodii 20g, Pericarpium Citri Reticulatae 2g, Cortex Magnoliae Officinalis 18g.Each raw material of above-mentioned weight is mixed, after grinding into fine powder and crossing 1500 mesh sieves, make granule, and dry compacting in flakes promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material by following weight: Rhizoma Gastrodiae 12g, Fructus Xanthii 30g, Herba Menthae 10g, Bombyx Batryticatus 12g, Herba Pogostemonis 10g, Flos Magnoliae 10g, two 20g of colluding, Herba Asari 4g, Periostracum Cicadae 10g, Rhizoma Pinelliae 18g, Radix Angelicae Dahuricae 20g, Rhizoma Ligustici 18g, Flos Chrysanthemi 10g, the 10g of river Qiang, Radix Polygalae 1g, Rhizoma Chuanxiong 18g, Radix Aucklandiae 20g, Herba chenopodii 20g, Pericarpium Citri Reticulatae 2g, Cortex Magnoliae Officinalis 18g.Each raw material of above-mentioned weight is mixed, after grinding into fine powder and crossing 80~200 mesh sieves, make pill promptly.
The clinical trial example
Medicine composite for curing chronic rhinitis patient's of the present invention clinical observation on the therapeutic effect test.
1. the physical data of subjects: adopt pharmaceutical composition of the present invention to treat 60 routine patients altogether, wherein male 35 examples, women 25 examples; The oldest person 74 years old, age reckling 8 years old.
2. Therapeutic Method:
Usage and consumption: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey every day three times, obey 3~6 at every turn, and every content of dispersion 0.3g, warm water takes.2) tablet: obey every day three times, obey 3~6 at every turn, every content of dispersion 0.3g, warm water takes.3) pill: obey every day three times, obey 8g at every turn, warm water takes.
The course of treatment: 15 days is a course of treatment, treats three courses of treatment altogether.
3. efficacy assessment standard:
Produce effects: Signs is significantly improved, the hyperemia of nasal cavity and mucous membrane of nasopharynx, edema, drying, hemorrhage, vasodilation transference cure; Purulent secretion disappears; Mucous membrane of maxillary sinus transfers pale red to by kermesinus.
Effectively: Signs makes moderate progress, and nasal cavity and congested, the no edema of mucous membrane of nasopharynx trace do not have drying, no hemorrhage, a small amount of vasodilation; The kermesinus of mucous membrane of maxillary sinus is thin out; Purulent secretion disappears, and has only a small amount of secretions.
Invalid: Signs does not have improvement, and nasal cavity and mucous membrane of nasopharynx hyperemia, edema, vasodilation also have neoplasm generation etc.; Mucous membrane of maxillary sinus is kermesinus, and the concha nasalis inferior front end is the Fructus Mori shape sometimes; Produce a large amount of sticking purulent secretions.
4. model case:
1) Zhao Bingli, woman, 61 years old, No. 32, Min Qiao street, Road Inside Area, Harbin.
In the period of the 2007-2008, the gas of having a stuffed up nose continues 2 years, and the sleep quality extreme difference also causes dizzy, headache.Hospital diagnosis is a chronic rhinitis, and deviation of nasal septum begins to take Western medicine, sx behind the clothes Western medicine, but sx after the drug withdrawal.The back Western medicine of stopping using begins to take medicine of the present invention, and it is good entirely to take after 13 days symptom, and mental restoration is normal, gets 30 days dosage of Chinese medicine subsequently again, continues treatment.
2) Wang Lei, the man, 33 years old, the employee of office firmly breathed out in Shijiazhuang Pharma Inc..
Suffered from long-term chronic rhinitis before 2010, cause the sleep quality extreme difference, also cause dizzy, headache, occur the sensation of suffocating often, make the Wang Lei energy wretched insufficiency that works by day, begin to take medicine of the present invention in May, 2010, it is normal to sleep after ten days, and the nasal obstruction situation is clearly better, and is conscious lighter than originally, now all are normal, not recurrence.
3) Liu Changjun, man, 38 years old, the technician of Harbin building enterprise.
In the period of the 2005-2009,, cause transferring chronic rhinitis to, continue to occur symptoms such as larynx is done, nasal obstruction, headache for a long time by acute rhinitis owing to working environment reason and not treatment in time.Remove hospital admission, adopt non-thermal plasma trap that it is treated, symptom is obviously alleviated, but the situation of recurrence occurs.Begin to take medicine of the present invention the end of the year 2009, take Chinese medicine after 20 days subjective symptoms fine, breathe smooth and easy, sleep is good, through the treatment recovery from illness of two courses of treatment, up to the present not recurrence.
4) Wang Hongbin, man 28 years old, the university students of Harbin City colleges and universities.
Came the Harbin City to study in college from southern city in 2008, and because the north of china in winter climate reasons causes it to suffer from chronic rhinitis, treated with Western medicine in hospital, symptom is alleviated to some extent in a short time, but often outbreak repeatedly of the state of an illness has a strong impact on normal learning life.Begin at the beginning of 2010 to take medicine of the present invention, take Chinese medicine after 15 days the chronic rhinitis symptom disappear substantially, adhere to taking 2 two courses of treatment of medicine of the present invention again, in 2010, recurring chronic rhinitis.
5) Wei Ning, woman, 16 years old, the high school student of Harbin City
Go out to suffer from chronic rhinitis from February, 2009 at examination in hospital, occur symptoms such as headache, nasal obstruction, hypopnea, lethargy during morbidity.April 1 began to use Drug therapy of the present invention then, further consultation on May 16 takes medicine that heavy-gravity secretions reduces in the posterula, and it is normal that olfactory sensation recovers, can ortho sleep, and spirit is also fine, normally studying and living.Half a year is after hospital's rhinoscopy shows that the nasal cavity purulent secretion disappears; Mucous membrane of maxillary sinus transfers pale red to by kermesinus.
6) Wu Guangrui, man, 34 years old, the worker of Harbin Utilities Electric Co..
Go out to suffer from chronic rhinitis from May, 2010 at examination in hospital, occur hypopnea, lethargy, nasal obstruction during morbidity, headache causes can not ortho sleep.Once obeyed Western medicine 1 year, symptom is alleviated to some extent, but the chronic rhinitis symptom increases the weight of to some extent after the drug withdrawal.After one month, take medicine of the present invention in drug withdrawal, just took an evident turn for the better after taking medicine ten days since on May 16th, 2011.Nasal obstruction, headache transference cure, spirit is relatively good after 30 days, can ortho sleep and work.
7) Sun Jie, woman, 47 years old, the work of Harbin City's institutional settings.
In the period of the 2006-2009 year, long-term intermittent nasal obstruction appears, with nasal mucosa swelling in various degree, be diagnosed as chronic hypertrophic rhinitis through hospital in May, 2009, by operative treatment, disease is alleviated to some extent, begins and occur the symptom of intermittent nasal obstruction, headache in July, 2010.October 16 began to take medicine of the present invention.Took medicine 10 days, further consultation on October 27, the headache symptom is clearly better, nasal obstruction a bit occasionally, it is fine to adhere to taking 1 month aftersensation spirit of medicine of the present invention again.
8) Fang Ye, woman, 67 years old, Daqing institutional settings retired cadre.
The chronic sinusitis history is arranged, and watery nasal discharge is many.At the beginning of 2008 4 months, intranasal often has the pain of doing, scratchy, normal band blood or blood crusts in the tears.Took Western medicine three months, symptom is alleviated to some extent, symptomatic recurrence after the drug withdrawal.On May 16th, 2009 began to take medicine of the present invention.Took medicine 15 days, various symptoms all alleviate, and continue to use 2 courses of treatment symptom complete obiteration, not recurrence up to now.
9) Wang Ruibo, man, 8 years old, Road Inside Area, Harbin City primary school student.
Not in time treat and then trouble rhinitis because of flu in November, 2011.Have a stuffy nose evening, and morning, time-out had a large amount of stickiness purulence tears, snivel during motion, and the normal distending pain of place between the eyebrows, local hospital diagnosis is the atrophic rhinitis.In the April, 2012 is taken medicine of the present invention, takes medicine continuously 15 days, and the watery nasal discharge symptom is clearly better, and adheres to taking medicine three courses of treatment, and the chronic rhinitis symptom all disappears, and the mental status is fine so far, and it is normal that learning life recovers.
10) Liu Chang, woman, 31 years old, Road Outside Area, Harbin City private owner.
In December, 2008 is suffered from chronic sinusitis, the hyperemia of nasal membrane kermesinus, and two concha nasalis inferior swelling, the visible purulent secretion of middle nasal meatus is not seen obvious neoplasm.Often with symptoms such as sensation of oppression over the chest with shortness of breath.In May, 2009, symptom was clearly better after hospital undergos surgery treatment, and in November, 2010, symptoms such as nasal obstruction headache appearred again in symptomatic recurrence.Begin to take medicine of the present invention in March, 2011, after 3 courses of treatment, various symptoms are obviously improved, and continue to take medicine 3 courses of treatment, and disease disappears, and the work life recovers normal.
11) principality is strong, man, 71 years old, the retired professor of Harbin City.
Because of the work reason often contacts dust, suffer from the chronic rhinitis several years, rose in 2009, headache appears, hypomnesis, symptoms such as rhinorrhea.Take the Western medicine relief of symptoms, but, often cause complication such as cardiovascular and cerebrovascular vessel because of older.Begin to take medicine of the present invention in October, 2009, after 2 courses of treatment, the headache transference cure, the watery nasal discharge symptom also alleviates to some extent.Continue three courses of treatment of medication, breathes smooth and easy, the pain disappearance, quality of life obviously improves.
12) Zhang Bin, man, 8 years old, Harbin City's Xiangfang District primary school student.
The anemofrigid cold malpractice causes chronic sinusitis, ill back nasal obstruction, rhinorrhea, and inappetence, hypomnesis has a strong impact on school grade.Begin to take medicine of the present invention in April, 2012, sx after the course of treatment, the pus tears disappear substantially, and the headache symptom is alleviated to some extent, continuous use 2 months, the nasal obstruction symptom is clearly better, and memory improves, and school grade has also been made significant headway.
13) Zhai Long, man, 32 years old, Road Inside Area, Harbin City private owner.
Suffered from allergic rhinitis in 2010, and showed as repeated cold, catch a cold once about two weeks, pharyngalgia, cough, symptoms such as the heat that occurs together, headache, sneeze, rhinorrhea, nasal cavity is itched, eyes are itched, nasal obstruction, dyspnea, low grade fever, lassitude.Behind the low-temperature plasma operative treatment, symptom takes a turn for the better, in JIUYUE, 2011 disease relapse.The oral medicine of the present invention of coughing in February, 2012, after 5 courses of treatment, all sxs, flu reduces, sneeze, flowing water sample nasal mucus obviously reduces, and the food drink is normal, and the mental status is fine.
14) Luo Jin, man, 12 years old, Harbin City's Nangang District primary school student.
Suffered from chronic rhinitis, and showed as nasal obstruction, watery nasal discharge, sneeze in 2010.Often feel dizziness headache, can not concentrate one's energy on class, fatigue and weakness, inappetence.Took the Western medicine of some treatment rhinitis, effect is also not obvious, worries that taking Western medicine for a long time has side effects.Begin to take medicine of the present invention in April, 2012, and behind the two weeks of taking medicine, sneeze, nasal obstruction situation are alleviated.Continue to take medicine two courses of treatment, the dizziness headache transference cure is breathed smooth and easyly, and diet is normal, and is full of vitality, and all are normal in learning life.
15) Jiang Meiduo, woman, 16 years old, the high student of Harbin City senior middle school.
Suffered from rhinitis in 2010, cause headache, nose one winddorn of suffering from cold swashs, will rhinorrhea, also can drop tears, and it is also ineffective to have eaten a lot of medicines, the treatment of can only suspending schooling.At the beginning of 2011, begin to take medicine of the present invention, after 1 month, the symptom of headache is clearly better, and continues to take medicine 3 months, sees cold wind watery nasal discharge transference cure, breathes smooth and easyly, and memory improves, and achievement also increases, and has been admitted to ideal senior middle school.Drug withdrawal lives that all are normal so far, and the state of an illness is not seen recurrence.
5. therapeutic outcome:
Among the 60 routine patients that treated, through the treatment of 3 courses of treatment, produce effects 34 examples wherein, effective 21 examples, invalid 5 examples, total effective rate reaches 91.7%.The result shows that pharmaceutical composition of the present invention has significant curative effect to the chronic rhinitis patient.

Claims (5)

1. pharmaceutical composition for the treatment of chronic rhinitis is characterized in that: be made up of following bulk drugs: 5 ~ 20 parts in Rhizoma Gastrodiae, 25 ~ 35 parts of Fructus Xanthii, 4 ~ 16 parts of Herba Menthaes, 5 ~ 20 parts of Bombyx Batryticatus, 4 ~ 16 parts of Herba Pogostemoniss, 4 ~ 16 parts of Flos Magnoliaes, two collude 10 ~ 30 parts, 2 ~ 10 parts of Herba Asaris, 4 ~ 16 parts of Periostracum Cicadaes, 10 ~ 25 parts of the Rhizoma Pinelliaes, 15 ~ 30 parts of the Radixs Angelicae Dahuricae, 12 ~ 25 parts of Rhizoma Ligustici, 5 ~ 15 parts of Flos Chrysanthemis, 5 ~ 15 parts of river Qiang, 1 ~ 5 part of Radix Polygalae, 15 ~ 25 parts of Rhizoma Chuanxiongs, 12 ~ 25 parts of the Radix Aucklandiae, 10 ~ 25 parts of Herba chenopodiis, 1 ~ 5 part of Pericarpium Citri Reticulatae, 10 ~ 25 parts of Cortex Magnoliae Officinalis.
2. according to the described pharmaceutical composition of claim 1, it is characterized in that: the weight portion of each crude drug is: 12 parts in Rhizoma Gastrodiae, 30 parts of Fructus Xanthii, 10 parts of Herba Menthaes, 12 parts of Bombyx Batryticatus, 10 parts of Herba Pogostemoniss, 10 parts of Flos Magnoliaes, two collude 20 parts, 4 parts of Herba Asaris, 10 parts of Periostracum Cicadaes, 18 parts of the Rhizoma Pinelliaes, 20 parts of the Radixs Angelicae Dahuricae, 18 parts of Rhizoma Ligustici, 10 parts of Flos Chrysanthemis, 10 parts of river Qiang, 1 part of Radix Polygalae, 18 parts of Rhizoma Chuanxiongs, 20 parts of the Radix Aucklandiae, 20 parts of Herba chenopodiis, 2 parts of Pericarpium Citri Reticulataes, 18 parts of Cortex Magnoliae Officinalis.
3. according to claim 1,2 described any pharmaceutical compositions, it is characterized in that: can method of Chinese medicinal routinely be prepared into any oral formulations commonly used.
4. according to the described pharmaceutical composition of claim 3, it is characterized in that: described oral formulations is pill, capsule, tablet or granule.
5. the application of the described arbitrary pharmaceutical composition of claim 1~4 in preparation treatment chronic rhinitis medicine.
CN2013101604199A 2013-05-05 2013-05-05 Medicinal composition for treating chronic rhinitis and preparation method thereof Pending CN103211984A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103977294A (en) * 2014-06-02 2014-08-13 杨小平 Traditional Chinese medicinal preparation for treating chronic nasopharyngitis and preparation method
CN104666952A (en) * 2015-02-15 2015-06-03 陈红 Traditional Chinese medicine composition for treating chronic rhinitis and preparation method of traditional Chinese medicine composition
CN109224060A (en) * 2018-11-30 2019-01-18 中商国能孵化器集团有限公司 A kind of pharmaceutical composition and the preparation method and application thereof for treating rhinitis

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103977294A (en) * 2014-06-02 2014-08-13 杨小平 Traditional Chinese medicinal preparation for treating chronic nasopharyngitis and preparation method
CN104666952A (en) * 2015-02-15 2015-06-03 陈红 Traditional Chinese medicine composition for treating chronic rhinitis and preparation method of traditional Chinese medicine composition
CN104666952B (en) * 2015-02-15 2016-03-02 侯明月 A kind of Chinese medicine composition for the treatment of chronic rhinitis and preparation method thereof
CN109224060A (en) * 2018-11-30 2019-01-18 中商国能孵化器集团有限公司 A kind of pharmaceutical composition and the preparation method and application thereof for treating rhinitis

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Application publication date: 20130724