CN103211580A - Method and device by utilizing pharynx voice reflection to detect human body pharynx wall tissue looseness - Google Patents
Method and device by utilizing pharynx voice reflection to detect human body pharynx wall tissue looseness Download PDFInfo
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Abstract
The invention belongs to the medical examination field and discloses a method by utilizing pharynx voice reflection to detect human body pharynx wall tissue looseness and a device by utilizing the pharynx voice reflection to detect the human body pharynx wall tissue looseness. The method by utilizing the pharynx voice reflection to detect the human body pharynx wall tissue looseness comprises the following steps: a single exhale movement is conducted under an appropriate resistance through a pharynx voice reflection detection device to measure phase cavum pharynx volume when a user exhales; a single inhale movement is conducted under appropriate resistance through the pharynx voice reflection detection device to measure phase cavum pharynx volume when the user inhales; and pharynx wall tissue looseness is a ratio acquired by using a difference value of the phase cavum pharynx volume when the user exhales and the phase cavum pharynx volume when the user inhales to divide a sum value of the phase cavum pharynx volume when the user exhales and the phase cavum pharynx volume when the user inhales. The method by utilizing the pharynx voice reflection to detect the human body pharynx wall tissue looseness can detect the human body pharynx wall tissue looseness in a noninvasion mode. The device by utilizing the pharynx voice to detect the human body pharynx wall tissue looseness can effectively detect the human body pharynx wall tissue looseness.
Description
Technical field
The invention belongs to field of medical examination, relate to a kind of method and device that utilizes pharynx sound reflecting human body pharynx wall organizational slack degree.
Background technology
The human body pharyngeal cavity is centered on by neck bone, muscle, trunk and other connective tissues and forms.Soft tissues such as muscle and other connective tissues are under normal circumstances kept certain force of strain, keep pharyngeal cavity enough unobstructed when breathing.Along with age or other factors change, pharyngeal cavity wall soft tissue physiological function changes, and the pharynx wall slackness increases, and pharynx wall is organized anti-tractive ability drop, may bring a series of pathological changes thus and causes disease.Therefore understanding pharynx wall soft tissue relaxation degree can help to judge the upper respiratory tract physiological status.Pharynx wall soft tissue relaxation degree exists than big-difference with race, age, or sex etc. is different, and under normal circumstances, youthful pharynx wall slackness is less, and the old people because connective tissue is lax and muscle tone under degradation may cause the pharynx wall slackness to increase.But under some pathologic conditions, because piling up, pharyngeal fatty tissue cause the pharynx wall slackness to increase such as possibilities such as obesities.At present, the method that does not also have a kind of non-invasive human body pharynx wall soft tissue relaxation degree in the world.
The original design purpose of existing pharynx sound reflecting technology (Acoustic pharyngometry) is to wish to understand person under inspection's pharyngeal cavity (or upper respiratory tract) volume and smallest cross-section area (being possible upper respiratory tract obstruction position and degree) by a kind of non-invasive detection method, for judging that sleep apnea provides a kind of auxiliary information.But because sleep apnea occurs under patient's sleep state mostly, how when clear-headed the asphyxia phenomenon can not take place, and pharynx sound reflecting detection technique need be carried out in that the patient is clear-headed, so testing result can not truly reflect the aeration status of upper respiratory tract when the patient sleeps.
Original pharynx sound reflecting detection method is to detect person under inspection pharyngeal cavity volume and smallest cross-section area when eupnea.Upper respiratory tract obstruction position and degree when as previously mentioned, sleep can not be truly reflected at detected smallest cross-section area absolute value and position during waking state.Detected pharyngeal cavity volume is pointed out in our experimental result, does not have significant difference between young group, person in middle and old age's group, obstructive sleep apnea (OSA) group.Therefore, existing pharynx sound reflecting detection technique clinical value is little.
Summary of the invention
The objective of the invention is provides a kind of method of utilizing pharynx sound reflecting human body pharynx wall organizational slack degree at above-mentioned technical problem.
Another object of the present invention provides a kind of pharynx sound reflecting checkout gear.
The objective of the invention is to realize by following technical measures:
A kind of method of utilizing sound reflecting human body pharynx wall organizational slack degree, this method comprises the following steps:
A. suitably carry out the single exhale action under the resistance by pharynx sound reflecting checkout gear, measuring phase pharyngeal cavity volume when exhaling;
B. suitably carry out the single aspiratory action under the resistance by pharynx sound reflecting checkout gear, measuring phase pharyngeal cavity volume when air-breathing;
When c. exhaling when air-breathing mutually pharyngeal cavity volume difference when exhaling when air-breathing the ratio of phase pharyngeal cavity volume sum gained be pharynx wall organizational slack degree.
Described method is wherein carried out the single exhale action and is meant that exhalation process keeps certain hour under suitable resistance under suitable resistance; Under suitable resistance, carry out the single aspiratory action and be meant that breathing process keeps certain hour under suitable resistance.
Described method, wherein suitably resistance is 7～13 centimeter water columns, preferred 10 centimeter water columns.Certain hour is 7-15 second, preferred 10 seconds.
Described method, wherein exhale action and aspiratory action difference duplicate detection is three times, and the 1st time is benchmark, and three times are detected pharyngeal cavity volume error＜5% is effective testing result.
The pharynx sound reflecting device that is used for human body pharynx wall organizational slack degree, this device are to install a drag devices additional at the open end of the detector tube of existing pharynx sound reflecting checkout gear (interface end offside).
Described device, wherein existing pharynx sound reflecting device is made of following parts: detector tube, acoustical generator, pick up, processor, output device, detector tube is a hollow pipe, one end is open, the other end is an interface end, detector tube one side links to each other with acoustical generator, acoustical generator is preferably placed on the detection tube wall near the open end, acoustical generator communicates with the detector tube hollow space by the hole of tube wall, and pick up is positioned at and detects the arbitrary position of tube wall, is preferably placed at and detects the tube wall centre position, pick up links to each other with processor by holding wire, processor is handled the signal that pick up transmits, and result is exported by output device, and output device is display or printer.
Described device, wherein drag devices can be kept the certain pressure of upper respiratory tract like this for having the resistance gauge of resistance display device (as Pressure gauge) or the Pressure gauge that communicates with the detector tube hollow space when detecting.
Below be specifying of the inventive method:
One, detection method principle:
1, utilizes pharynx sound reflecting technology for detection pharyngeal cavity physiological status;
Malleation rising in the pharyngeal cavity when 2, exhaling, the pharyngeal cavity volume expansion; Pharyngeal cavity is negative pressure state when air-breathing, and the pharyngeal cavity volume dwindles.Can judge the pharynx wall slackness from pharyngeal cavity volume-variation situation.If testing result prompting pharynx wall slackness is little then show that the pharynx wall soft tissue tension is bigger, anti-tractive ability is strong, is not easy to take place the upper respiratory tract locking of subsiding when the pharyngeal cavity bearing certain pressure changes.If the pharynx wall slackness is big, then point out a little less than the anti-tractive ability of pharynx wall soft tissue, the upper respiratory tract locking of subsiding when bearing pressure and change, pharyngeal cavity takes place easily.
Two, detect content:
1, detection method: the person under inspection gets seat, at first detects pharyngeal cavity volume (Fig. 2 A) by the pharynx sound reflecting under the eupnea state.Under certain resistance (10 centimeter water column), make single exhale action (Fig. 2 B) then, be continuously for 10 seconds, detect the pharyngeal cavity volume by pharynx sound reflecting device.The last single aspiratory action (Fig. 2 C) of doing under certain resistance (10 centimeter water column) detects the pharyngeal cavity volume by pharynx sound reflecting device.Exhale action and aspiratory action be duplicate detection three times respectively, with the first time testing result be benchmark, three times are detected error＜5% is effective testing result.
2, the result judges: pharynx sound reflecting testing result is judged: as shown in Figure 3, and pharynx sound reflecting curve when the top is expiration, pharynx sound reflecting curve when the below is air-breathing.In distance front tooth 10-20 cm range, measure the pharyngeal cavity volume.Pharynx wall organizational slack degree (F) when phase pharyngeal cavity volume difference is with expiration during phase/air-breathing when exhaling mutually/ratio of phase pharyngeal cavity volume sum is represented when air-breathing.Computing formula is as follows:
Illustrate: F is a pharynx wall organizational slack degree (Floppiness), phase pharyngeal cavity volume when Vexh is expiration, phase pharyngeal cavity volume when Vinh is air-breathing.
Beneficial effect of the present invention:
The present invention utilizes pharynx sound reflecting technology, adopts specific detection method, and the human body pharynx wall is organized under the certain pressure condition pharynx wall and organizes anti-tractive ability, is the method for a kind of non-invasive human body pharynx wall soft tissue relaxation degree.Checkout gear provided by the invention is human body pharynx wall soft tissue relaxation degree more effectively.
The present invention is by pharynx sound reflecting technology for detection person under inspection pharyngeal cavity wall slackness, though can not be directly used in certain specific disease of clinical diagnosis, can for judgement under sleep state, the trend that pharyngeal cavity subsides whether may occur provides Useful Information.By detecting the pharynx wall slackness, (Continuing Positive Airway Pressure, the prediction patient uses the compliance and the therapeutic effect of this treatment means when CPAP) treating using continuous positive airway pressure device also can to help the clinician in addition.Be that the bigger patient's result of use of pharynx wall slackness is better, and the less patient of pharynx wall slackness often is not easy to tolerate the CPAP treatment.
Description of drawings
Fig. 1, pharynx sound reflecting checkout gear sketch map (A) and the present invention detect sketch map (B).
Fig. 2, common pharynx sound reflecting detection and pharynx wall slackness detection method sketch map.
The pharynx sound reflecting detected when wherein A was for eupnea, B during for exhale action the pharynx sound reflecting detect, the pharynx sound reflecting detected when C was the aspiratory action signal.
Fig. 3, the signal of pharynx sound reflecting testing result.
Wherein: pharyngeal cross-sectional area curve when the top fine rule is expiration, pharyngeal cross-sectional area curve when the below thick line is air-breathing.Article two, be between the dotted line apart from front tooth 10-20cm pharyngeal cavity span.
Fig. 4, pharynx sound reflecting detect exhales-inhales pharyngeal cavity difference in volume result relatively under eupnea pharyngeal cavity volume and the resistive state.
Wherein: exhale under the resistive state between young group and person in middle and old age's group, person in middle and old age's group and the OSA group-when inhaling mutually pharyngeal cavity difference in volume result significant difference (p＜0.05) is more all arranged, young group and person in middle and old age organize, person in middle and old age organize and OSA organize between during eupnea pharyngeal cavity volume testing result more all do not have significant difference (p〉0.05).
Fig. 5, different age people collection OSA patient pharynx wall slackness are relatively
Wherein: young group is organized the pharynx wall slackness with person in middle and old age relatively significant difference (p=0.047), and person in middle and old age's group relatively has significant difference (p＜0.01) with OSA group pharynx wall slackness.
Young group is organized the pharynx wall slackness relatively with person in middle and old age under Fig. 6, the different pressures condition.
Fig. 7, human body incidence CT image sketch map.
The specific embodiment
The invention will be further elaborated by the following examples.
Embodiment 1: apparatus of the present invention
Pharynx sound reflecting checkout gear of the present invention is that (USA) open end of detector tube (interface end offside) installs a drag devices (Fig. 1) additional for Echovision, Sleep Group Solutions at existing pharynx sound reflecting checkout gear.
Existing pharynx sound reflecting device is made of following parts: pharynx sound reflecting detector tube (abbreviation detector tube), acoustical generator, pick up, processor, output device, detector tube is a hollow pipe, one end is open, the other end is an interface end, detector tube one side links to each other with acoustical generator, acoustical generator is preferably placed on the detection tube wall near the open end, acoustical generator communicates with the detector tube hollow space by the hole of tube wall, pick up (can be turnover pickup) is positioned at and detects the arbitrary position of tube wall, be preferably placed at and detect the tube wall centre position, pick up links to each other with processor by holding wire, processor is handled the signal that pick up transmits, and result exported by output device, output device is display or printer.The gauge tap of checkout gear can be arranged on the tube wall of detector tube, also can be arranged on other positions, is principle with convenient the use.
The improvement that the present invention did is that the open end (being that this detector tube is the middle siphunculus of a perforation) at detector tube connects a drag devices, and this drag devices is for to have the resistance gauge of resistance display device (as Pressure gauge) or directly to connect a Pressure gauge that communicates with the detector tube hollow space.Drag devices can exhaled and cause certain malleation or the negative pressure of pharyngeal cavity generation, the concrete pressure limit when Pressure gauge can help the person under inspection to understand actual detected when air-breathing.In addition, a mouthpiece is set, during use mouthpiece is linked to each other with the interface end of detector tube in the interface end of detector tube.One timer or intervalometer can also be set in the optional position of this checkout gear.
The using method of apparatus of the present invention:
The interface end that during use mouthpiece is inserted into detector tube (if do not consider to prevent cross infection, can not adopt mouthpiece, also can realize the present invention.In order to prevent cross infection, when detecting, each person under inspection all uses disposable mouthpiece, this moment, mouthpiece also can claim blow gun), the person under inspection sucks that mouthpiece is exhaled or is air-breathing, exhale or keep suitable dynamics and time that (the great efforts I is observed when air-breathing from the Pressure gauge of the drag devices that links to each other with the detector tube other end, time can be held voluntarily or be observed by timer by the person under inspection, also can adopt intervalometer control, setting-up time one is to promptly cutting off detection signal), open sense switch, this moment drag devices, detector tube, mouthpiece, pharyngeal cavity forms the big cavity of a connection, tone generator sends audio signal, in big cavity, form concussion, thereby produce reflected signal (the pharyngeal cavity wall also can be subjected to concussion to produce reflected signal simultaneously), reflected signal and sonorific signal are obtained by pick up, convert the signal of telecommunication to and reach processor through holding wire, treated reservation pharyngeal cavity wall reflected signal, other signals of elimination, analyzing pharyngeal cavity wall reflected signal draws and exhales or the pharyngeal cavity volume of certain limit (apart from front tooth 10-20cm scope) when air-breathing, calculate pharynx wall organizational slack (F), the result exports by output device, as showing by display or going out relevant information by printer prints.
Embodiment 2: two kinds of different technologies pharyngeal cavities of different crowd volume testing result relatively
1, study population: 64 normal person volunteers, male: 44 people, women: 22 people; Young group 24 people (30.2 ± 6.3 years old mean age), person in middle and old age organize 40 people (50.2 ± 6.1 years old mean age).25 (mean aves: 45.2 ± 9.1) of obstructive sleep apnea (OSA) patient.
2, research method: the person under inspection gets seat, at first detects pharyngeal cavity volume (Fig. 2 A) by the pharynx sound reflecting under the eupnea state.Under certain resistance (10 centimeter water column), make single exhale action (Fig. 2 B) then, be continuously for 10 seconds, detect the pharyngeal cavity volume by pharynx sound reflecting device.The last single aspiratory action (Fig. 2 C) of doing under certain resistance (10 centimeter water column) detects the pharyngeal cavity volume by pharynx sound reflecting device.Exhale action and aspiratory action be duplicate detection three times respectively, with the first time testing result be benchmark, three times are detected error＜5% is effective testing result.
3, the result judges: pharynx sound reflecting testing result is judged: as shown in Figure 3, and pharynx sound reflecting curve when the top is expiration, pharynx sound reflecting curve when the below is air-breathing.In distance front tooth 10-20 cm range, measure the pharyngeal cavity volume.Because the pharyngeal cavity volume does not have difference when air-breathing mutually exhaling during eupnea, gets pharyngeal cavity volume absolute value and compares in three groups of crowds.Pharyngeal cavity volume difference compares in three groups of crowds to adopt after the drag devices testing result to get when exhaling when air-breathing mutually.
The results are shown in Figure 4.The result shows: exhale under the resistive state between young group and person in middle and old age's group, person in middle and old age's group and the OSA group-when inhaling mutually pharyngeal cavity difference in volume result significant difference (p＜0.05) is more all arranged, young group and person in middle and old age organize, person in middle and old age organize and OSA organize between during eupnea pharyngeal cavity volume testing result more all do not have significant difference (p〉0.05).
Embodiment 3: different crowd pharynx wall slackness testing result relatively
1, study population: 64 normal person volunteers, male: 44 people, women: 22 people; Young group 24 people (30.2 ± 6.3 years old mean age), person in middle and old age organize 40 people (50.2 ± 6.1 years old mean age).25 (mean aves: 45.2 ± 9.1) of obstructive sleep apnea (OSA) patient.
2, research method: the person under inspection gets seat, at first makes single exhale action (Fig. 2 A) under certain resistance (10 centimeter water column), is continuously for 10 seconds, detects the pharyngeal cavity volume by pharynx sound reflecting device.Under certain resistance (10 centimeter water column), make single aspiratory action (Fig. 2 B) then, detect the pharyngeal cavity volume by pharynx sound reflecting device.Exhale action and aspiratory action be duplicate detection three times respectively, with the first time testing result be benchmark, three times are detected error＜5% is effective testing result.
3, the result judges: pharynx sound reflecting testing result is judged: as shown in Figure 2, and pharynx sound reflecting curve when the top is expiration, pharynx sound reflecting curve when the below is air-breathing.In distance front tooth 10-20 cm range, measure pharyngeal cavity volume and smallest cross-section area position and absolute value.Pharynx wall organizational slack degree (F) when phase pharyngeal cavity volume difference is with expiration during phase/air-breathing when exhaling mutually/ratio of phase pharyngeal cavity volume sum is represented when air-breathing.
The results are shown in Figure 5.The result shows: young group is organized the pharynx wall slackness with person in middle and old age relatively significant difference (p=0.047), and person in middle and old age's group relatively has significant difference (p＜0.01) with OSA group pharynx wall slackness.
Embodiment 4: the research of suitable detection pressure setting
In theory, the pressure of expiration and air-breathing generation is big more during detection, and the volumetrical difference of pharyngeal cavity is big more between expiratory phase and the inspiratory phase.In order to select suitable detected pressures, we carry out implementing under the different detected pressures conditions to detect the experiment of pharynx wall slackness 10 volunteers (young group 5 people, person in middle and old age organize 5 people).Pharynx wall slackness detection method is with embodiment 2 and embodiment 3.Detected pressures is respectively 5cm water column, 7cm water column, 10cm water column, 13cm water column and 15cm water column.
Testing result: under 5cm water column pressure condition, pharyngeal cavity volume difference does not relatively have significant difference (p〉0.05) when young group and person in middle and old age's group calling-air-breathing; Under 7cm water column condition, relatively there were significant differences (p＜0.05) for pharyngeal cavity volume difference when young group and person in middle and old age's group calling-air-breathing, and person under inspection's comfort level is relatively poor; Under 10cm water column condition, relatively there were significant differences (p＜0.05) for pharyngeal cavity volume difference when young group and person in middle and old age's group calling-air-breathing, and person under inspection's comfort level is moderate; Under 13cm water column condition, relatively there were significant differences (p＜0.05) for pharyngeal cavity volume difference when young group and person in middle and old age's group calling-air-breathing, and person under inspection's comfort level is relatively poor; Under 15cm water column condition, 6 persons under inspection (60%) can't finish detection (Fig. 6).
Embodiment 5: pharyngeal cavity volume detection range defines
Because comprising from front tooth, pharynx sound reflecting testing result begins overall process to trachea.Its central incisor is the oral cavity scope to the soft palate free edge, and it is subjected to the influence of tongue body tissue location, and volume-variation is bigger.Comprising the volumetrical testing result in oral cavity has little significance.We define apart from front tooth 10-20cm scope to swallowing acoustic emission detection pharyngeal cavity volume effective range by to 79 routine human body incidence CT imaging data Measurement and analysis.(Fig. 7, table 1).
Table 1 human body front tooth is to soft palate free edge and glottis range measurements
Through measuring, front tooth apart from soft palate free edge distance at 8-10cm(average 8.81) about, front tooth apart from the glottis distance at 14-18cm(average 15.1) about.
Claims (8)
1. a method of utilizing sound reflecting human body pharynx wall organizational slack degree is characterized in that this method comprises the following steps:
A. suitably carry out the single exhale action under the resistance by pharynx sound reflecting checkout gear, measuring phase pharyngeal cavity volume when exhaling;
B. suitably carry out the single aspiratory action under the resistance by pharynx sound reflecting checkout gear, measuring phase pharyngeal cavity volume when air-breathing;
When c. exhaling when air-breathing mutually pharyngeal cavity volume difference when exhaling when air-breathing the ratio of phase pharyngeal cavity volume sum gained be pharynx wall organizational slack degree.
2. method according to claim 1 is characterized in that carrying out the single exhale action and is meant that exhalation process keeps certain hour under suitable resistance under suitable resistance; Under suitable resistance, carry out the single aspiratory action and be meant that breathing process keeps certain hour under suitable resistance.
3. method according to claim 1 and 2 is characterized in that suitable resistance is 7～13 centimeter water columns.
4. method according to claim 3 is characterized in that suitable resistance is 10 centimeter water columns.
5. method according to claim 1 is characterized in that exhale action and aspiratory action difference duplicate detection three times, and the 1st time is benchmark, and three times are detected pharyngeal cavity volume error＜5% is effective testing result.
6. the pharynx sound reflecting device that is used for human body pharynx wall organizational slack degree is characterized in that installing a drag devices additional in the open end of the detector tube of existing pharynx sound reflecting checkout gear.
7. device according to claim 6, it is characterized in that existing pharynx sound reflecting device is made of following parts: detector tube, acoustical generator, pick up, processor, output device, detector tube is a hollow pipe, one end is open, the other end is an interface end, detector tube one side links to each other with acoustical generator, acoustical generator is preferably placed on the detection tube wall near the open end, acoustical generator communicates with the detector tube hollow space by the hole of tube wall, pick up is positioned at and detects the arbitrary position of tube wall, be preferably placed at and detect the tube wall centre position, pick up links to each other with processor by holding wire, processor is handled the signal that pick up transmits, and result is exported by output device, and output device is display or printer.
8. device according to claim 6 is characterized in that drag devices is to have the resistance gauge of resistance display device or the Pressure gauge that communicates with the detector tube hollow space.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310137201.1A CN103211580B (en) | 2013-04-18 | 2013-04-18 | A kind of method and device utilizing acoustic pharyngealmetry human body pharyngeal wall tissue slackness |
| PCT/CN2013/079727 WO2014169541A1 (en) | 2013-04-18 | 2013-07-19 | Method and apparatus for detecting looseness of pharynx wall tissue of human body by using pharynx voice reflection |
| US14/769,176 US9647550B2 (en) | 2013-04-18 | 2015-05-25 | Negative voltage signal generation circuit |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310137201.1A CN103211580B (en) | 2013-04-18 | 2013-04-18 | A kind of method and device utilizing acoustic pharyngealmetry human body pharyngeal wall tissue slackness |
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| CN103211580A true CN103211580A (en) | 2013-07-24 |
| CN103211580B CN103211580B (en) | 2015-12-23 |
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| CN203458371U (en) * | 2013-04-18 | 2014-03-05 | 镇江市第一人民医院 | Pharynx sound-reflecting detecting tube and device for detecting looseness of pharynx wall tissue therethrough |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK172149B1 (en) * | 1994-11-15 | 1997-12-01 | Rhinometrics A S | Apparatus for examining and measuring constrictions or passages in organic cavities by means of acoustic reflectometry |
| US20050005935A1 (en) * | 2001-09-18 | 2005-01-13 | Gradon Lewis George | Respiratory apparatus and methods of respiratory treatment |
| GB0329884D0 (en) * | 2003-12-23 | 2004-01-28 | Glaxo Group Ltd | Method |
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2013
- 2013-04-18 CN CN201310137201.1A patent/CN103211580B/en not_active Expired - Fee Related
- 2013-07-19 WO PCT/CN2013/079727 patent/WO2014169541A1/en active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6183423B1 (en) * | 1998-05-14 | 2001-02-06 | Respironics, Inc. | Breathing disorder prescreening device and method |
| US6443907B1 (en) * | 2000-10-06 | 2002-09-03 | Biomedical Acoustic Research, Inc. | Acoustic detection of respiratory conditions |
| WO2012052882A1 (en) * | 2010-10-20 | 2012-04-26 | Koninklijke Philips Electronics N.V. | Method and apparatus for diagnosing obstructive sleep apnea with an awake patient |
| CN203458371U (en) * | 2013-04-18 | 2014-03-05 | 镇江市第一人民医院 | Pharynx sound-reflecting detecting tube and device for detecting looseness of pharynx wall tissue therethrough |
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| Publication number | Publication date |
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| CN103211580B (en) | 2015-12-23 |
| WO2014169541A1 (en) | 2014-10-23 |
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