CN103190624A - Dendrobium officinale and composition of extract thereof - Google Patents
Dendrobium officinale and composition of extract thereof Download PDFInfo
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Abstract
The invention discloses dendrobium officinale and a composition of extracts of the dendrobium officinale. The composition is characterized by comprising the following components in percentage by weight of each unit package: 15-75% of dendrobium officinale, 80-10% of the dendrobium officinale extract, and 5-15% of auxiliary materials. Not only can the effective ingredients of the dendrobium officinale be extracted and combined, but also the effective ingredients are accurately measured, and moreover the polysaccharide content of the extract of the composition is greater than 30%; and the composition not only ensures the goodness and the completeness of the effective ingredients and the amino acid in the dendrobium officinale, but also is convenient to take when being made into tablet sugar (any one of solid beverage, powder, granule, capsule, tablet, uncoated tablet, coated tablet, dispersible tablet, buccal tablet and the like), thereby being sanitary, comfortable in taste, thorough in absorption, free of waste, convenient to carry over and store, and remarkable in effect.
Description
Technical field
The present invention relates to food or functional food field, be specifically related to food or functional food composition that a kind of composition that contains the iron sheet stem of noble dendrobium and extract thereof is made.
Background technology
The stem of noble dendrobium has long medicinal history in China, and Shennong's Herbal is put down in writing its " in main wound, except thin thin, the reinforcing yin essence of numbness, the therapeutic method to keep the adverse qi flowing downward, tonifying five zang organs consumptive disease, for a long time obey thick stomach "; Compendium of Material Medica thinks that it can " reinforcing yin essence benefit be smart, and thick stomach is never sufficient in the benefit, flat stomach Qi, longue meat, intelligence development is made light of one's life by commiting suicide and prolonged life except frightened ", unique effect is arranged aspect keeping fit treating disease.
Supplementary Amplifications of the Compendium of Materia Medica (clear Zhao Xuemin) record: the stem of noble dendrobium " clearing stomach is promoted the production of body fluid except abnormal heat, strain, with for tea, Appetizing spleen-tonifying, wind is treated in arresting convulsion, can press down saliva phlegm, relieving summer-heat, sweet fragrant sending down abnormally ascending ".
One one of the version Pharmacopoeia of the People's Republic of China recorded in 2010: " [nature and flavor with return through] hardship is slightly cold the stem of noble dendrobium.Return stomach, kidney channel.[function with cure mainly] reinforcing stomach reg fluid is nourishing Yin and clearing heat.Be used for the moon and hinder body fluid deficiency, the dry polydipsia, food is few retches, abnormal heat after being ill, order is secretly not clear.”
Modern study shows, the main medicinal ingredient of dendrobium candidum has: dendrobium polysaccharide, dendrobine, amino acid, luxuriant and rich with fragrance class and 100 plurality of active ingredients such as bibenzyl compound, trace element and to human body beneficial's active component, have the immunity of enhancing, anti-oxidant (delaying senility), clearing protect throat, liver-nourishing and eyesight-improving, alleviating physical fatigue, invigorating the spleen benefit lung, auxiliary hyperglycemic, auxiliary antilipemic, beautifying face and moistering lotion, antitumor, promote to digest, relax bowel, effects such as hemangiectasis, strengthening the muscles and bones, nourishing kidney yin.
Along with social progress and economic development, human healthy growing interest to self.Since the nineties in 20th century, global resident's healthy consumption is soaring year by year, and is very vigorous to the demand of nutrient and healthcare products.In the 15 class internationalization industries of dividing by international standard, medicines and health protection is one of fastest-rising five industries of world commerce, and sales volume every year of health food is with 13% speed increment.And from the Chinese health products trade of the eighties in 20th century starting, theoretical and have on the basis of edible health care product traditional habit in the health of " tonic diseases prevention, conditioning after being ill ", in short time more than ten years, developed the industry that becomes a uniqueness rapidly.Why flourish the health products industry is, and main cause is that living standards of the people obviously improve; Secondly, the change of people's lives mode is the important opportunity of health products industry development; Multi-level social life needs, for the development of health products industry provides the broad space.
According to open statistics, from July, 2003 so far, the about kind more than 5000 of State Food and Drug Administration (SFDA) the homemade health food of approval, import health food kind more than 200.It wherein is the about kind more than 60 of functional food that primary raw material is made with the stem of noble dendrobium.
Because the distinguished health-care efficacy of dendrobium candidum, industry is consistent thinks that extraordinary development prospect is arranged.But because the stem of noble dendrobium is in situation in imminent danger for a long time in the past, for the most Chinese people, a lot of people also are not familiar with and understand dendrobium candidum, do not know its effect, do not understand instructions of taking.Below be the certain situation of present stem of noble dendrobium product:
1, Tiepi Fengdou, be with the stem of dendrobium candidum through overbaking, the spherical or helical form dry product that curls and make, also be traditional dendrobium candidum medicinal material product.Characteristics are traditional converted products, weighing easily; Shortcoming is in the rolled state, and being not easy to recognize is real dendrobium candidum; Simultaneously, adding man-hour because baking is uneven, the nexine part mildews easily, often needs when taking to untie, and its active ingredient is to be difficult to absorb, boil for a long time, endure, etc.; Chewing if directly be contained in the mouth, also can be a kind of instructions of taking originally, but bradymassesis often has the worry of aspects such as sanitation and hygiene.
2, dendrobium tea is to be that raw material is pulverized the tea in bag that processes a little with the disconnected paragraph joint that produces in the stem of noble dendrobium processing maple bucket process, or not have the dendrobium tea that packs; Characteristics are to have utilized pipe nipple, disconnected joint, and puff tea comes convenient, can be quantitative to raw material.The tea in bag based on the stem of noble dendrobium that is added with other Chinese medicine or health products is also arranged, as " natural blood-sugar reducing tea, the tea made from the stem of noble dendrobium, radix polygonati officinalis, the tuber of dwarf lilyturf, radix glehniae, sweet tea, white tea that also has produce dendrobium flowers to do; Weak point is the stem of noble dendrobium slag that has often added other, as Dendrobium aphyllum (Roxb.) C. E. Fisch, dendrobium loddigesii Rolfe, purple dendrobium etc.; Main problem be the polysaccharide of dendrobium candidum in the process of simple bubble, often polysaccharide is difficult for stripping or stripping is less, can not obtain more effectively utilizing.
3, to have single be that raw material is made with the stem of noble dendrobium to dendrobium wine, and it is that raw material is made that the stem of noble dendrobium with other kind is arranged, and also has the stem of noble dendrobium and other medicinal material compatibility to make, and the number of degrees of most wine are not high, used seasonings such as sugar, honey.Characteristics are taking conveniences, catered to hobby drink, wish again can health the people; Dendrobium wine has been owing to dissolved in pure dissolubility, the water-soluble substances in the stem of noble dendrobium, headache not after often drinking, and the side effect after liquor-saturated is alleviated, and pure dissolubility, water-soluble substances can access utilization; Weak point is that what to be added is the stem of noble dendrobium of what kind, and the consumer is bad to be determined.If what add is dendrobium candidum, polysaccharide component is difficult to be utilized preferably.
4, dendrobium candidum powder and micropowders can be processed with the disconnected joint of the stem of noble dendrobium in the processing maple bucket, and also the Tiepi Fengdou that can make good use of is processed.General owing to expensive, adopt big box, inner wrapping more.Characteristics are quantitative convenience, take more convenient, the suitable gift box of doing; Shortcoming is that the consumer is difficult to determine whether the stem of noble dendrobium powder of the inside is simply processed by the dendrobium candidum raw material entirely.Be that quantity is few in addition, add exquisite packing, particularly micropowders, price is more expensive; The powder immediate access feels bad, and it is serious to stick to one's teeth.
5, the dendrobium candidum capsule is the raw material dress with the dendrobium candidum powder, and the zero capsules of maximum that adopt are packed more, and the smart powder 0.45-0.47 gram of the stem of noble dendrobium of can packing in general every capsules is sold in pack into then bottle or the box.The capsule with dendrobium stem that compound is also arranged.The dendrobium candidum capsule also is the major product of external dendrobium candidum.Characteristics; Can be meticulousr quantitatively, be easy to carry taking convenience; Shortcoming; The enterprise that prestige generally need be arranged, what allow the trustworthy real packing of people is the dendrobium candidum powder, dose is big.
6, the application of the bright product of dendrobium candidum, advantage are to be convenient to recognize, are not easy to be pretended to be by other kind, do not have the loss of the vitamin aspect that causes in the process, and be fresh etc.; Shortcoming is that fresh-keeping expense is expensive, is not easy to carry, and takes inconvenience;
7, the brief introduction of stem of noble dendrobium medicine and analysis:
Stem of noble dendrobium cream (compound), the stem of noble dendrobium, selfheal, radix scrophulariae, Herba Ecliptae, blood clam, Asian puccoon, indigo naturalis.
The stem of noble dendrobium loose the stem of noble dendrobium (removing root) HERBA EPIMEDII (file) each 30 the gram rhizoma atractylodis (rice a swill soak, cut, the roasting) 15 the gram.
28 flavor medicinal materials such as stem of noble dendrobium sheet [main component] stem of noble dendrobium, genseng, antelope's horn, the fruit of Chinese magnoliavine, the fruit of Chinese wolfberry, Ligusticum wallichii, Chinese yam, glutinous rehmannia, Radix Angelicae Sinensis (steeping in wine).
Can see that the medicine that the stem of noble dendrobium is made is compound preparation entirely! Though improved curative effect, the compound medicine will just can be taken through doctor's advice.
Fresh dendrobium candidum plant is difficult for storage, the dendrobium candidum raw material that baking is made through low baking temperature-maple bucket, and after processing, amino acid whose composition being damaged in various degree.People in the process of the edible bright product stem of noble dendrobium and Tiepi Fengdou with the aquatic foods product stewed chicken duck flesh of fish, bright product squeeze the juice, maple struggles against and is ground into powder and directly gulps down powder and eat or be ground into powder and be pressed into tablets, these all rest in the raw-material application, not only unhygienic when edible, the mouthfeel of swallowing is poor, the more important thing is that its active ingredient can not effectively absorb, cause the wasting of resources, and eat the cost costliness every day.According to dendrobium candidum the human nutrition demand is calculated, human body must just can reach health or result for the treatment of by edible 10-15g every day.At present, the price of 1g Tiepi Fengdou is at 28-30 unit/g on the market, and by minimum food sanitation standard and calculation of price, one day expense is at 280 yuan.
At present, the cream of invading of some single extracts is arranged also on the market, and single edible a certain composition, will lose the amino acid of rich multiple health, medicinal ingredient and needed by human of dendrobium candidum, not obvious on the health effect.
Invention disclosed patent: " a kind of compound Herba Dendrobii extract composition that delays senility ", CN 103007052 A, the applying date: on December 14th, 2012, a kind of traditional Chinese medicine extraction compositions is provided, dendrobium candidum extract 20-25%, American ginseng extract 20-25%, Fructus lycii P.E 31-35% forms.
In sum, the stem of noble dendrobium Related product weak point of list marketing is to exist to take inconvenience, formulation is simple, the main active ingredient of dendrobium candidum (dendrobium polysaccharide, dendrobine, amino acid, luxuriant and rich with fragrance class and bibenzyl compound etc.) can not obtain more effectively utilizing, and active ingredient is difficulty or directly take problems such as the raw material dose is big quantitatively.Except above-mentioned ubiquitous weak point, main problem is the bad control of dose, eats to cause absorbing not exclusively just to excrete waste more; Eat and do not reach effect less.
So, needing a kind of invention be the raw material combination thing with dendrobium candidum and extract thereof, and food prepared therefrom or functional food again are as compressing tablet sugar, solid beverage based food, or food or functional food such as powder, granule, capsule, tablet, plain sheet, coating tablet, dispersing tablet, buccal tablet.The user is easy to carry in order to product, taking convenience, more be conducive to product day dose and reach human body optimal absorption effect, both economical, safety again.
Summary of the invention
The composition of a kind of dendrobium candidum and extract thereof is characterized in that: component and the weight quota thereof of per unit packing are:
Dendrobium candidum: 15-75%
Dendrobium candidum extract: 80-10%
Auxiliary material: 5-15%.
Component and the weight quota preferred version thereof of described per unit packing are:
Dendrobium candidum: 65%
Dendrobium candidum extract: 25%
Auxiliary material: 10%.
Described dendrobium candidum refers to weak foot dendrobium candidum and hard pin dendrobium candidum.
Described dendrobium candidum extract refers to comprise dendrobium polysaccharide, dendrobine, luxuriant and rich with fragrance class and bibenzyl compound etc.
The dendrobium polysaccharide composition of the composition of described dendrobium candidum and extract thereof is greater than 30%.
Described auxiliary material refers to comprise dolomol, starch, superfine silica gel powder, PVP.
The preferred version of described auxiliary material is:
Dolomol 1%
Starch 4%
Superfine silica gel powder 3%
PVP 2%.
The per unit packing of the described composition that contains the iron sheet stem of noble dendrobium and extract thereof refers among the compressing tablet sugar, solid beverage, powder, granule, capsule, tablet, plain sheet, coating tablet, dispersing tablet, buccal tablet of unit packaging any one.
The preparation of compositions method step of described dendrobium candidum and extract thereof is as follows:
(1) be raw material with the dendrobium candidum, choose, clean, dry, pulverize, obtain the former powder of dendrobium candidum;
(2) be raw material with the dendrobium candidum, flooding is used in coarse crushing, extract simmer down to liquid extract; Add precipitation with alcohol, supernatant reclaims ethanol, and drying precipitate, fine powder are broken, namely get dendrobium candidum extract powder.
Described dendrobium candidum powder, the dendrobium candidum extract adds auxiliary material, is mixed into the composition of dendrobium candidum and extract thereof.
The reprocessing of described composition is made in compressing tablet sugar, solid beverage based food, powder, granule, capsule, tablet, plain sheet, coating tablet, dispersing tablet, the buccal tablet any one.
In described preparation method's step (1), selection is that non-dendrobium candidum class material is removed; Cleaning is that silt is removed in the stem of noble dendrobium cleaning after will choosing with running water; Drying is will clean the back stem of noble dendrobium at 80 ℃ to be dried to and to contain moisture＜8%; Pulverizing is that dendrobium candidum after the drying is pulverized to behind the granularity 80 purpose powder, and oversize is removed in screening, and it is the former powder of dendrobium candidum under 200 mesh sieves that screenings is crushed to granularity again.
In described preparation method's step (2), coarse crushing refers to that with the dendrobium candidum coarse crushing be 1～3cm dendrobium candidum extract meal.
Add the pure water lixiviate 3 times in described preparation method's step (2), each 60 minutes, first, second and third time amount of water was respectively 4 times of amounts of stem of noble dendrobium weight, 3 times of amounts, 3 times of amounts, and extraction temperature is 95～100 ℃.
The thickening temperature of extract is 95～100 ℃ in described preparation method's step (2), and it is 1.2～1.25 that 40 ℃ of heat of liquid extract are surveyed proportion.
Add the ethanol that precipitation with alcohol refers to add 5 times of weight of liquid extract in described preparation method's step (2), stirred 20 minutes, precipitation left standstill 24 hours; Carry out 2 times.
Precipitation with alcohol thing baking temperature is 60～65 ℃ in described preparation method's step (2), vacuum-0.04～-0.06Mp; Fine powder broken iron Herba Dendrobii extract is granularity 200 purpose dendrobium candidum extract powder.
Ethanol is 95% food grade ethanol in described preparation method's step (2).
The composition tablet curative effect table of dendrobium candidum and extract thereof:
Dendrobium candidum of the present invention (Latin formal name used at school: Dendrobium officinale Kimura et Migo), be the perennial herbaceous plant that grows nonparasitically upon another plant of the orchid family (Orchidaceae) Dendrobium (Dendrobium Sw.).
The marked improvement of the composition of a kind of dendrobium candidum of the present invention and extract thereof is: the composition of dendrobium candidum and extract thereof, not only with each extracts active ingredients of dendrobium candidum, combination, and each active ingredient accurate measurement, and the dendrobium polysaccharide content of the composition of dendrobium candidum and extract thereof is greater than 30%, composition has not only guaranteed each active ingredient of dendrobium candidum and amino acid whose intact and complete, and take convenient, healthy, comfortable taste, absorb thoroughly, can not waste, be easy to carry, store, its effect brilliance.Simultaneously, dendrobium candidum composition amount every day seldom, taking convenience, more be conducive to product day dose and reach human body optimal absorption effect, both economical, safety again.
The price of dendrobium candidum composition is only directly eating raw-material 50%.According to dendrobium candidum the human nutrition demand is calculated, human body must just can reach health or result for the treatment of by edible 10-15g every day.At present, the price of 1g Tiepi Fengdou is at 28-30 unit/g on the market, and by minimum food sanitation standard and calculation of price, one day expense is at 280 yuan.
The specific embodiment
Embodiment 1
The tablet that the composition of a kind of dendrobium candidum and extract thereof is made, component and the weight quota thereof of per unit packing are:
Dendrobium candidum: 15%
Dendrobium candidum extract: 80%
Auxiliary material: 5%.
Wherein the weight quota of auxiliary material is:
Dolomol 1%
Starch 2%
Superfine silica gel powder 1%
PVP 1%.
Preparation method's step of the tablet that the composition of described dendrobium candidum and extract thereof is made is as follows:
(1) be raw material with the dendrobium candidum, choose, clean, dry, pulverize, obtain the former powder of dendrobium candidum;
(2) be raw material with the dendrobium candidum, flooding is used in coarse crushing, extract simmer down to liquid extract; Add precipitation with alcohol, supernatant reclaims ethanol, and drying precipitate, fine powder are broken, namely get dendrobium candidum extract powder.
The former powder of described dendrobium candidum, the dendrobium candidum extract adds auxiliary material, is mixed into the composition of dendrobium candidum and extract thereof.
In described preparation method's step (1), selection is that non-dendrobium candidum class material is removed; Cleaning is that silt is removed in the dendrobium candidum cleaning after will choosing with running water; Drying is will clean the back stem of noble dendrobium at 80 ℃ to be dried to and to contain moisture＜8%; Pulverizing is that dendrobium candidum after the drying is pulverized to behind the granularity 80 purpose powder, and oversize is removed in screening, and it is the former powder of dendrobium candidum under 200 mesh sieves that screenings is crushed to granularity again.
In described preparation method's step (2), coarse crushing refers to that with the dendrobium candidum coarse crushing be 1～3cm dendrobium candidum extract meal.
Add the pure water lixiviate 3 times in described preparation method's step (2), each 60 minutes, first, second and third time amount of water was respectively 4 times of amounts of dendrobium candidum weight, 3 times of amounts, 3 times of amounts, and extraction temperature is 95～100 ℃.
The thickening temperature of extract is 95～100 ℃ in described preparation method's step (2), and it is 1.2～1.25 that 40 ℃ of heat of liquid extract are surveyed proportion.
Add the ethanol that precipitation with alcohol refers to add 5 times of weight of liquid extract in described preparation method's step (2), stirred 20 minutes, precipitation left standstill 24 hours; Carry out 2 times.
Precipitation with alcohol thing baking temperature is 60～65 ℃ in described preparation method's step (2), vacuum-0.04～-0.06Mp; Fine powder broken iron Herba Dendrobii extract is granularity 200 purpose dendrobium candidum extract powder.
Ethanol is 95% food grade ethanol in described preparation method's step (2).
According to said components and weight quota thereof, reprocessing tablet.
Embodiment 2
The tablet that the composition of a kind of dendrobium candidum and extract thereof is made, component and the weight quota thereof of per unit packing are:
Dendrobium candidum: 65%
Dendrobium candidum extract: 25%
Auxiliary material: 10%.
Wherein the weight quota of auxiliary material is:
Dolomol 1%
Starch 4%
Superfine silica gel powder 3%
PVP 2%.
Preparation method's step of the tablet that the composition of described dendrobium candidum and extract thereof is made repeats no more with embodiment 1.
Embodiment 3
The tablet that the composition of a kind of dendrobium candidum and extract thereof is made, component and the weight quota thereof of per unit packing are:
Dendrobium candidum: 75%
Dendrobium candidum extract: 10%
Auxiliary material: 15%.
Wherein the weight quota of auxiliary material is:
Dolomol 3%
Starch 5%
Superfine silica gel powder 4%
PVP 3%.
Preparation method's step of the tablet that the composition of described dendrobium candidum and extract thereof is made repeats no more with embodiment 1.
Claims (8)
1. the composition of a dendrobium candidum and extract thereof, it is characterized in that: component and the weight quota thereof of per unit packing are:
Dendrobium candidum: 15-75%
Dendrobium candidum extract: 80-10%
Auxiliary material: 5-15%.
2. the composition of a kind of dendrobium candidum according to claim 1 and extract thereof, it is characterized in that: the component of described per unit and weight quota preferred version thereof are:
Dendrobium candidum: 65%
Dendrobium candidum extract: 25%
Auxiliary material: 10%.
3. the composition of a kind of dendrobium candidum according to claim 1 and extract thereof is characterized in that: described dendrobium candidum refers to weak foot dendrobium candidum and hard pin dendrobium candidum.
4. the composition of a kind of dendrobium candidum according to claim 1 and extract thereof, it is characterized in that: described dendrobium candidum extract refers to comprise dendrobium polysaccharide, dendrobine, luxuriant and rich with fragrance class and bibenzyl compound etc.
5. the composition of a kind of dendrobium candidum according to claim 4 and extract thereof, it is characterized in that: the dendrobium polysaccharide composition of the composition of described dendrobium candidum and extract thereof is greater than 30%.
6. the composition of a kind of dendrobium candidum according to claim 1 and extract thereof, it is characterized in that: described auxiliary material refers to comprise dolomol, starch, superfine silica gel powder, PVP.
7. the composition of a kind of dendrobium candidum according to claim 6 and extract thereof, it is characterized in that: the preferred version of described auxiliary material is:
Dolomol 1%
Starch 4%
Superfine silica gel powder 3%
PVP 2%.
8. the composition of a kind of dendrobium candidum according to claim 1 and extract thereof is characterized in that: the composition of described dendrobium candidum and extract thereof refers to any one among compressing tablet sugar, solid beverage, powder, granule, capsule, tablet, plain sheet, coating tablet, dispersing tablet, the buccal tablet.
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| CN103445190A (en) * | 2013-09-12 | 2013-12-18 | 江门市浩伦生态农业有限公司 | Method for extracting dietary fibers from dendrobium officinale |
| CN104069366A (en) * | 2014-06-23 | 2014-10-01 | 广西圣保堂药业有限公司 | Stock dendrobium officinale preparation and preparation method thereof |
| CN104642702A (en) * | 2015-03-19 | 2015-05-27 | 郝燕 | Preparation method of noble dendrobium stem preserved fruits |
| CN105614889A (en) * | 2016-01-27 | 2016-06-01 | 霍山鑫隆农林科技有限公司 | Dendrobium huoshanense flower essence tablet and preparation method thereof |
| CN106138748A (en) * | 2016-07-27 | 2016-11-23 | 浙江省磐安县外贸药业有限公司 | A kind of Herba Dendrobii Capsulae Radix Panacis Quinquefolii and preparation method thereof |
| CN106579437A (en) * | 2016-12-15 | 2017-04-26 | 湖南利诺生物药业有限公司 | Rhizoma polygonati odorati health-care product with fatigue alleviating and anti-oxidization functions and preparation method thereof |
| CN109380725A (en) * | 2018-12-13 | 2019-02-26 | 浙江兰溪锦荣生物科技股份有限公司 | A kind of dendrobium nobile chewable tablets and preparation method thereof containing dendrobium nobile soluble dietary fiber |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103445190A (en) * | 2013-09-12 | 2013-12-18 | 江门市浩伦生态农业有限公司 | Method for extracting dietary fibers from dendrobium officinale |
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| CN104642702A (en) * | 2015-03-19 | 2015-05-27 | 郝燕 | Preparation method of noble dendrobium stem preserved fruits |
| CN105614889A (en) * | 2016-01-27 | 2016-06-01 | 霍山鑫隆农林科技有限公司 | Dendrobium huoshanense flower essence tablet and preparation method thereof |
| CN106138748A (en) * | 2016-07-27 | 2016-11-23 | 浙江省磐安县外贸药业有限公司 | A kind of Herba Dendrobii Capsulae Radix Panacis Quinquefolii and preparation method thereof |
| CN106579437A (en) * | 2016-12-15 | 2017-04-26 | 湖南利诺生物药业有限公司 | Rhizoma polygonati odorati health-care product with fatigue alleviating and anti-oxidization functions and preparation method thereof |
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Application publication date: 20130710 |