CN103142795A - Traditional Chinese medicinal preparation for treating avascular necrosis of femoral head - Google Patents

Traditional Chinese medicinal preparation for treating avascular necrosis of femoral head Download PDF

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CN103142795A
CN103142795A CN2013101015103A CN201310101510A CN103142795A CN 103142795 A CN103142795 A CN 103142795A CN 2013101015103 A CN2013101015103 A CN 2013101015103A CN 201310101510 A CN201310101510 A CN 201310101510A CN 103142795 A CN103142795 A CN 103142795A
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radix
blood
traditional chinese
chinese medicinal
femoral head
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CN103142795B (en
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赵振德
杜晓燕
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Abstract

The invention discloses a traditional Chinese medicinal preparation for treating avascular necrosis of femoral head. The preparation is prepared from the following Chinese medicinal herbs by weight: 10-20g of radix codonopsis, 30-50g of astragalus, 10-12g of radix rehmanniae preparata, 10-12g of angelica, 10-12g of white peony root, 6-10g of ligusticum wallichii, 10-12g of epimedium, 10g of curculigoside, 10-12g of drynaria, 10-12g of antlers, 10-12g of dogwood, 12-15g of medlar, 12-15g of achyranthes, 10-12g of dipsacus, 10-12g of stir-baked semen persicae, 10-12g of safflower, 10g of resina draconis, 10-12g of eupolyphaga, 10g of licorice, and 6g of stir-fried pangolin. The complete formula can alternate qi and blood, mutually change Yin and Yang, strengthen tendons and bones, promote blood circulation to remove blood stasis, and moderate etiology and pathogenesis to reach the purpose of healing. Through a clinical trial, the traditional Chinese medicine preparation disclosed by the invention has the characteristics of good curative effect, small side effects, low cost and the like, and is convenient to use.

Description

A kind of Chinese drugs agentia for the treatment of ischemic necrosis of femoral head
Technical field:
The present invention is a kind of Chinese drugs agentia for the treatment of ischemic necrosis of femoral head.
Background technology:
Ischemic necrosis of femoral head is to interrupt because wound or other causes of disease cause blood supply of the femoral head the comprehensive disease that causes, is commonly encountered diseases, the frequently-occurring disease in clinical orthopaedics, and very high disability rate is arranged.Except the cause of disease of wound clearly, other causes of disease are understood fully pathogeny not yet fully.In recent years, the femur head necrosis sickness rate constantly increases, and causes the hip arthralgia, limitation of activity, limping, have a strong impact on healthy, disability even.The western medical treatment aspect, 1,2,3 phases gave bone decompression, capsule decompression, and most of effect is undesirable.
Chinese medicine is " osteomyelitis card " take primary disease as " rheumatism involving the bone ", its etiology and pathogenesis is that the resistance of hip wound and hyperamization arthralgia due to blood stasis, QI-blood circulation are not smooth, muscles and bones is lost foster in QI and blood honor or element is had a liking for tobacco and wine, heat is burnt the cloudy liquid of Liver and kidney and caused deficiency of both QI and blood, negative and positive are two loses or permanent long journey, the prolonged walking injuring tendons of bearing a heavy burden, prolonged standing injuring bones causes deficiency of both QI and blood, deficiency of the liver and kindey for a long time, the resistance of blood stasis numbness, muscles and bones mistake is supported and sent out is rheumatism involving the bone.Chinese medicine is thought liver governing tendons, kidney governing bones, and blood stasis due to qi deficiency, the handsome blood of gas use traditional Chinese medical science organic conception, dialectical opinion to control.Method by benefiting QI and nourishing blood, liver and kidney tonifying, promoting blood circulation to remove obstruction in the collateral makes QI and blood and suitable, blood stasis from loose, and reaches the purpose of healing.The specific drug that is used for the treatment of clinically at present femur head necrosis is still rare, and Chinese medicinal formulae is more, and its curative effect is once poor uneven, can't apply clinically.
Summary of the invention:
The purpose of this invention is to provide and a kind of ischemic necrosis of femoral head is had definite curative effect, and Chinese medicinal formulae easy to use, that side effect is little, with low cost---Yiqi Huoxue Decoction.
Ingredients of the present invention by its weight ratio is:
Radix Codonopsis 10-12g, Radix Astragali 30-50g, Radix Rehmanniae Preparata 10-12g, Radix Angelicae Sinensis 10-12g,
Radix Paeoniae Alba 10-12g, Rhizoma Chuanxiong 6-10g, Herba Epimedii 10-12g, Rhizoma Curculiginis 10g,
Rhizoma Drynariae 10-12g, Cornu Cervi 10-12g, Fructus Corni 10-12g, Fructus Lycii 12-15g,
Radix Achyranthis Bidentatae 12-15g, Radix Dipsaci 10-12g, Semen Persicae (parched) 10-12g, Flos Carthami 10-12g,
Sanguis Draxonis 10g, Eupolyphaga Seu Steleophaga 10-12g, Radix Glycyrrhizae 10g, stir-fry Squama Manis 6g.
Said medicine was soaked one hour with water 1500ml, first caused with intense fire to boil, then used slow fire boiling 20-30 minute, leached medicinal liquid, then added water 1200ml slow fire boiling 15-20 minute, leached medicinal liquid; The secondary medicinal liquid is mixed and made into decoction.
Instructions of taking: every day potion, minute sooner or later a secondary is taken, 15 days courses for the treatment of.
The function of each medicine of the present invention cure mainly into:
Radix Codonopsis: sweet, flat, enter spleen, lung meridian, function invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst etc.
The Radix Astragali: sweet, warm, enter lung, spleen channel, the effects such as function benefiting QI for strengthening the superficies, diuretic detumescent, expelling pus and toxin by strengthening QI, granulation promoting.Be used for arthromyodynia deficient qi and blood, stagnate obstructed, due to pain, numbness be called arthralgia due to stagnation of blood person.
Radix Rehmanniae Preparata: sweet, tepor, enter liver, kidney channel, the five internal organs are enriched blood, nourished to function benefiting qi and nourishing yin, life essence-filling, marrow-benefitting, spermatogenesis to control the card of blood deficiency.Be used for all cards of blood deficiency, also can be used for hectic fever hectic fever due to YIN-deficiency, the night sweat of deficiency of kidney yin, the disease such as quench one's thirst.
Radix Angelicae Sinensis: sweet, hot, warm, enter liver, the heart, spleen channel, function nourishes blood and enriches blood, and promoting blood circulation and stopping pain is used for blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
The Radix Paeoniae Alba: picric acid, be slightly cold, enter liver, spleen channel, function enrich blood yin fluid astringing, easing the affected liver to relieve pain, yin fluid astringing is received antiperspirant.Be used for the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency.
Rhizoma Chuanxiong: hot, warm, enter liver, gallbladder, pericardium channel, the function blood-activating and qi-promoting, wind-expelling pain-stopping, blood vessels pass unimpeded.Be used for the treatment of traumatic injury, sore swollen toxin, rheumatic arthralgia, limbs pain, headche due to wind-cold etc.
Herba Epimedii: hot, sweet, warm.Enter liver, kidney channel.The function kidney-replenishing, strengthening the tendons and bones, expelling wind and removing dampness.Be used for the treatment of soreness of the waist and knees, rheumatic arthralgia, hemiplegia, extremity are meciless etc.
Rhizoma Curculiginis: hot, warm, slightly poisonous.Enter kidney, Liver Channel, function has the effect of reinforcing the kidney and supporting YANG, benefiting essence-blood, bone and muscle strengthening and promoting the circulation of blood detumescence, is mainly used in the diseases such as chronic consumptive disease internal injury and bones and muscles pain.
Rhizoma Drynariae: bitter in the mouth, temperature.Enter liver, kidney channel.Function the kidney invigorating bone strengthening continues and hinders pain relieving.Be used for lumbago due to renal deficiency, falling winks frustrates, the muscle fracture wound.
Cornu Cervi Degelatinatum: salty, warm.Enter liver, kidney channel.The function warming the kidney to activate YANG, astringing to arrest bleeding.Be used for the carbuncle sucutaneous nodule, skin infection disunion of a specified duration etc.
Fructus Corni: sour, puckery, tepor.Enter liver, kidney channel.The function liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating, controlling nocturnal emission with astringent drugs reducing urination, hidroschesis.Be used for vertigo and tinnitus, soreness of waist and knee joint, the profuse sweating collapse, interior-heat is quenched one's thirst.
Fructus Lycii: sweet, flat, enter liver, kidney, lung meridian.The function tonification Liver and kidney, treatment is had a dizzy spell due to deficiency of the liver and kindey, visual deterioration, soreness of the waist and knees, the disease such as quench one's thirst.
Radix Cyathulae: sweet, little hardship, flat enters liver, kidney, urinary bladder channel.The function eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.Be used for arthralgia, sufficient health clonic spasm of the muscle, injury from falling down.
Radix Dipsaci: toil tepor.Enter liver, kidney channel.Function invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, continuous folding wound, only metrorrhagia.Be used for aching pain in waist and back, the foot and knee being feeble, traumatic injury, incised wound, the carbuncle skin ulcer is swollen.
Semen Persicae (parched): bitter, sweet flat, enter lung, liver, large intestine channel, the function blood circulation promoting and blood stasis dispelling, moisturize laxation.Yong Yu WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Flos Carthami: hot, warm, enter the heart, Liver Channel, the effect of function promoting blood circulation to remove obstruction in the collateral, stasis-dispelling and pain-killing.Be used for lochia , mass in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Sanguis Draxonis: sweet, flat, enter liver, spleen channel, function promoting blood circulation to remove blood stasis, removing obstruction in the collateral to relieve pain.Being used for controlling blood stasis has a pain.Be used for traumatic injury, congestion detumescence hemostasia and promoting granulation.
Eupolyphaga Seu Steleophaga: salty, cold, slightly poisonous.Enter Liver Channel, function blood-activating analgetic, removing mass collateral dredging, the reason that relieves internal heat wound, reunion of bone are used for the diseases such as traumatic injury, abdominal pain due to blood stasis.
Fry Squama Manis: salty, be slightly cold, enter liver, kidney channel, function detumescence suppurations, scattered silt collateral dredging, invigorating blood circulation analgesia are used for that the carbuncle skin ulcer swells, anemofrigid-damp arthralgia, hemostasis, disease crust gather.
Radix Glycyrrhizae: sweet, flat, enter liver, stomach, lung meridian.With middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.Process use, control weakness of the spleen and stomach, lack of appetite, the loose stool of suffering from abdominal pain, overstrain heating, consumptive lung disease cough, cardiopalmus , Jing Epilepsy; Give birth to use, control laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.
In the side with Radix Codonopsis, Radix Astragali QI invigorating; Radix Rehmanniae Preparata, Radix Angelicae Sinensis, the Radix Paeoniae Alba are enriched blood; Herba Epimedii, Rhizoma Curculiginis, Rhizoma Drynariae, Cornu Cervi Degelatinatum, Fructus Corni, Fructus Lycii, Radix Dipsaci liver and kidney tonifying; Semen Persicae (parched), Flos Carthami, Sanguis Draxonis, Eupolyphaga Seu Steleophaga, stir-fry Squama Manis, Radix Achyranthis Bidentatae blood circulation promoting and blood stasis dispelling collateral dredging; Radix Glycyrrhizae is sweet flat, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Perfect square can make the QI and blood alternate, and negative and positive are changed mutually, bone and muscle strengthening, blood circulation promoting and blood stasis dispelling, the moderate cause of disease, pathogenesis and reach the purpose of healing.
Through clinic trial, total effective rate reaches 96.3%.Therefore the present invention has good effect, and easy to use, side effect is little, the characteristics such as with low cost.
The specific embodiment:
The invention provides and a kind of ischemic necrosis of femoral head is had definite curative effect, and Chinese medicinal formulae easy to use, that side effect is little, with low cost---Yiqi Huoxue Decoction.
Ingredients of the present invention by its weight ratio is:
Radix Codonopsis 10-12g, Radix Astragali 30-50g, Radix Rehmanniae Preparata 10-12g, Radix Angelicae Sinensis 10-12g,
Radix Paeoniae Alba 10-12g, Rhizoma Chuanxiong 6-10g, Herba Epimedii 10-12g, Rhizoma Curculiginis 10g,
Rhizoma Drynariae 10-12g, Cornu Cervi 10-12g, Fructus Corni 10-12g, Fructus Lycii 12-15g,
Radix Achyranthis Bidentatae 12-15g, Radix Dipsaci 10-12g, Semen Persicae (parched) 10-12g, Flos Carthami 10-12g,
Sanguis Draxonis 10g, Eupolyphaga Seu Steleophaga 10-12g, Radix Glycyrrhizae 10g, stir-fry Squama Manis 6g.
Said medicine was soaked one hour with water 1500ml, first caused with intense fire to boil, then used slow fire boiling 20-30 minute, leached medicinal liquid, then added water 1200ml slow fire boiling 15-20 minute, leached medicinal liquid; The secondary medicinal liquid is mixed and made into decoction.
Instructions of taking: every day potion, minute sooner or later a secondary is taken, 15 days courses for the treatment of.
Points for attention: anemia of pregnant woman's forbidding, the hyperpietic is cautious use of.
Clinical observation on the therapeutic effect:
Curative effect determinate standard:
Produce effects: hip joint function takes a turn for the better, and during heavy burden, pain disappears.X line prompting femoral head density, bone trabecula are obviously repaired, and the cryptomere shadow dwindles or disappears, and recovers normal life and heavy burden work.
Effectively: hip joint function takes a turn for the better to some extent, after bearing a heavy burden, slight pain is occasionally arranged, and the X line discloses femur head necrosis reparation, and life can be taken care of oneself, and can be competent at light work.
Invalid: the contrast for the treatment of before and after look, function, symptom, sign takes a turn for the better not obvious, and the X line discloses femur head necrosis without improvement.
Clinical experiment 114 examples, severe patient 4 examples wherein, severe patient 7 people, moderate patient 65 people, patients with mild 38 examples.Average 4 courses for the treatment of, therapeutic effect such as following table:
Classification Classification Produce effects Effectively Invalid
Seriously 4 3 ? 1
Severe 7 4 2 1
Moderate 65 13 51 1
Slightly 38 13 25 0
Add up to (%) 114(100) 37(28.9) 79(68.4) 4(2.6)
Untoward reaction: carry out tracing observation for 86 routine patients in therapeutic process, do not find obvious untoward reaction.
Therefore through clinic trial, the present invention has good effect, and easy to use, side effect is little, the characteristics such as with low cost.
Model case:
Case 1: Feng XX, the man, 46 years old, the builder, when construction traumatic injury before 2 years, the hip arthralgia closely over the past half year, aversion to cold and cold limbs, movable unfavorable, the pale tongue tongue is white, a little less than deep-thready pulse.2 phases of femur head necrosis are shown in the X-ray film inspection.We treat one course for the treatment of of January, treatment transference cure 5 course for the treatment of, and X-ray film shows normal, follows up a case by regular visits to half a year, NERC.
Case 2: king XX, the man, 60 years old, have a liking for tobacco and wine, two hip pain, limitation of activity, two hip fear of cold, purplish tongue, stringy and thready pulse is puckery.X-ray film shows three phases of femur head necrosis, with bone capsule decompression treatment poor effect, need hold up and turn and could walk, add treatment by Chinese herbs April after pain symptom disappear, the X-ray film improvement is walked substantially need not hold up and is turned.Follow up a case by regular visits to after half a year, the state of an illness is without recurrence.
Case 3: Liu, female, 43 years old, right lateral thigh head necrosis, the right side have a pain in the leg bitterly, and be handicapped, once many hospitalizes, took for a long time western medicine, all do not feel any better, begin to take medicine of the present invention in February, 2010, every day potion, one the course for the treatment of pain relief, treat after 3 months, pain disappears, right leg-training energy normal, check the necrotic zone remarkable improvement half a year, after 1 year, functional rehabilitation is normal.

Claims (1)

1. Chinese drugs agentia for the treatment of ischemic necrosis of femoral head, it is characterized in that: its ingredients by its weight ratio is:
Radix Codonopsis 10-12g, Radix Astragali 30-50g, Radix Rehmanniae Preparata 10-12g, Radix Angelicae Sinensis 10-12g,
Radix Paeoniae Alba 10-12g, Rhizoma Chuanxiong 6-10g, Herba Epimedii 10-12g, Rhizoma Curculiginis 10g,
Rhizoma Drynariae 10-12g, Cornu Cervi 10-12g, Fructus Corni 10-12g, Fructus Lycii 12-15g,
Radix Achyranthis Bidentatae 12-15g, Radix Dipsaci 10-12g, Semen Persicae (parched) 10-12g, Flos Carthami 10-12g,
Sanguis Draxonis 10g, Eupolyphaga Seu Steleophaga 10-12g, Radix Glycyrrhizae 10g, stir-fry Squama Manis 6g.
CN201310101510.3A 2013-03-27 2013-03-27 Traditional Chinese medicinal preparation for treating avascular necrosis of femoral head Expired - Fee Related CN103142795B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104069229A (en) * 2014-01-03 2014-10-01 杨忠好 Femoral head necrosis rehabilitation powder
CN106728610A (en) * 2016-12-28 2017-05-31 魏道德 Logical blood bolus for reinforcing bones of human body

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1319414A (en) * 2001-01-19 2001-10-31 刘军 Medicine for treating hecrosis of femoral head
CN1389252A (en) * 2002-07-24 2003-01-08 李如元 Composite medicine for treating femoral head necrosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100357033B1 (en) * 2000-12-14 2002-10-18 삼성전자 주식회사 Mounting structure for panel-type speaker

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1319414A (en) * 2001-01-19 2001-10-31 刘军 Medicine for treating hecrosis of femoral head
CN1389252A (en) * 2002-07-24 2003-01-08 李如元 Composite medicine for treating femoral head necrosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨凯: "股骨头缺血性坏死中医药治疗进展", 《辽宁中医药大学学报》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104069229A (en) * 2014-01-03 2014-10-01 杨忠好 Femoral head necrosis rehabilitation powder
CN106728610A (en) * 2016-12-28 2017-05-31 魏道德 Logical blood bolus for reinforcing bones of human body

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