CN103142210B - Peripheral refraction measuring method based on OCT technology - Google Patents
Peripheral refraction measuring method based on OCT technology Download PDFInfo
- Publication number
- CN103142210B CN103142210B CN201310059943.7A CN201310059943A CN103142210B CN 103142210 B CN103142210 B CN 103142210B CN 201310059943 A CN201310059943 A CN 201310059943A CN 103142210 B CN103142210 B CN 103142210B
- Authority
- CN
- China
- Prior art keywords
- oct
- image
- peripheral refraction
- measuring method
- method based
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention relates to a peripheral refraction measuring method based on OCT (optical coherence tomography) technology. The peripheral refraction measuring method based on OCT technology comprises the following steps: an OCT system is used for one-time imaging to refraction medium and retina inside an bulbus oculi so as to obtain OCT image; image processing software is used for analyzing OCT image so as to obtain forms and range information of all refraction interfaces and retina; an optical path tracing method is used for obtaining center refractive power in the visual axis direction and peripheral refraction force forming any angle with a visual axis; and the difference value of the peripheral refraction force at any angle and the center refraction force is calculated so as to obtain the peripheral refraction force value. According to the method, all that is needed is to acquire full-eye OCT image in one step through a full-eye imaging high resolution OCT system, ongoing implementation can be processed through software, and the method is quick and accurate in measuring.
Description
Technical field
The present invention relates to medical science and optoelectronic areas, be specifically related to a kind of peripheral refraction measuring method based on OCT technology.
Background technology
The concept of peripheral refraction is equaled to propose for 1931 by Ferree at first, and peripheral refraction power refers to the refractive power in the peripheral visual field that forms an angle with the optical axis, the retrobulbar focus state of the light namely formed an angle with the optical axis.According to focus and the amphiblestroid relative position of incident ray, the state such as myopia, relative hypermetropia relatively also can be divided into.Central authorities and peripheral refraction power are the main indexs of intactly appraiser's refraction of eye state.More toward periphery, the numerical value of peripheral refraction power and the difference of central refractive power larger, and there will be astigmatism and the higher order aberratons such as spherical aberration, coma.
Peripheral refraction power is having great importance in clinical ophthalmology and scientific research, has become myopia studies and the common test item of pediatric ophthalmology at present.(1) peripheral refraction power is the key factor affecting mypia progression.Study verified: myopia peripheral refractive state is different with emmetropia, shows as periphery relative hypermetropia, the stimulation of this periphery out of focus can cause axis oculi to increase, thus causes mypia progression; Although make c gl make the light focusing of boresight direction at macula lutea, because periphery is still in relative hypermetropia state, still myopia development can be caused.(2) peripheral refraction is the key factor of regulation and control human eye emmetropization process.Zoopery shows, the size of peripheral refraction power and character, plays an important role in the growth course of regulation and control eyeball.
The method of current measurement peripheral refraction power is the infrared eye refractometer utilizing the open visual field, is guided the rotation of eye position or head position, the optical axis of eyeball and apparatus measures light are formed an angle, thus measures the peripheral refraction number of degrees of this angle by a set of fixation object.There is obvious defect in these methods: when (1) eye position is rotated, because extraocular muscles contraction can affect Posterior pole eyeball shape; (2) by existing measuring method, subject's head is fixed on instrument bracket, and below is placed on jaw holder, forehead is close to E Tuo, watching sighting target attentively and be fixed on instrument front, but there is individual variation relative to the position of forehead due to forehead, eyeball, there is certain error in taking measurement of an angle of peripheral refraction.(3) Measuring Time is long, and by existing routine, the peripheral refraction power measuring 7 angles at least needs 40 minutes, if count the time of mydriasis in, needs 1.5 hours; And measured mostly is the child of more than 10 years old, the reduction of fitness directly affects measurement result.(4) due to the reason of (2), sighting target can only be set in some fixing angles, therefore, peripheral refraction at any angle cannot be measured.(5) watch sighting target attentively to be generally arranged at the moment, the nearly perception of experimenter can be caused to regulate, affect result.
Summary of the invention
According to the deficiencies in the prior art, the invention provides a kind of peripheral refraction measuring method based on OCT technology, the method measures fast accurate.
According to the deficiencies in the prior art, technical scheme provided by the invention is: a kind of peripheral refraction measuring method based on OCT technology, and described method comprises:
Utilize OCT system to carry out one-time imaging to intraocular refracting media and retina, obtain OCT image;
Image processing software is utilized to analyze described OCT image, to obtain each refractive interface and amphiblestroid form and range information;
Utilize optical path-tracing method, obtain the central optical power of boresight direction and become the peripheral refraction power of unspecified angle with the described optical axis;
Calculate the described peripheral refraction power of described unspecified angle and the difference of described central optical power, obtain peripheral refraction value thus.
Described OCT system is the high-resolution depth scan OCT system of full eye imaging.
Described optical path-tracing method is realized by ZEMAX optical path-tracing simulation softward.
Described OCT system is made up of anterior ocular segment depth scan OCT and oculi posterior segment OCT, described anterior ocular segment depth scan OCT can corneal and whole crystalline lens imaging, described oculi posterior segment OCT can to retina image-forming, by the OCT image of synchronous scanning, sample eye more complete in double focusing probe, image acquisition and image integration technical limit spacing.
Described OCT image is two dimensional image or 3-D view, described OCT image each refractive interface of clear display and retina.
Described refracting media comprises cornea, anterior chamber and crystalline lens.
The described peripheral refraction measuring method based on OCT technology, wherein the method for image procossing comprises:
First noise reduction process is carried out to image;
Adopt boundary extraction algorithm, the border of each organizational interface is extracted, if 3-D view, on the basis of Boundary Extraction, also needs to carry out image registration and three-dimensional reconstruction;
Form and the range information at each interface is obtained according to the boundary information extracted.
The invention has the beneficial effects as follows: the method only needs the OCT image of the full eye of the disposable acquisition of high-resolution OCT system by full eye imaging, and follow-up realization can pass through software processes, the method measures fast accurate.
Accompanying drawing explanation
Accompanying drawing 1 is the schematic diagram of the high-resolution OCT system of full eye imaging.
Accompanying drawing 2 is the schematic diagram of the OCT two dimensional image of full eye.
Accompanying drawing 3 is each refractive interface and amphiblestroid form schematic diagram.
Detailed description of the invention
As shown in Figure 1, Figure 2 and Figure 3: a kind of peripheral refraction measuring method based on OCT technology, described method comprises:
Utilize the high-resolution depth scan OCT system of full eye imaging, this OCT system is made up of anterior ocular segment depth scan OCT and oculi posterior segment OCT, anterior ocular segment depth scan OCT can corneal and whole crystalline lens imaging, oculi posterior segment OCT can to retina image-forming, by synchronous scanning, sample than double focusing probe, image acquisition and image integration technology, one-time imaging is carried out to intraocular refracting media (comprising cornea, anterior chamber and crystalline lens) and retina, obtain OCT two dimension or the 3-D view of full eye, OCT image each refractive interface of clear display and retina.
Utilize image processing software to analyze described OCT image, first noise reduction process is carried out to image; Adopt boundary extraction algorithm again, the border of each organizational interface is extracted, if three-dimensional volumetric image, on the basis of Boundary Extraction, also need to carry out image registration and three-dimensional reconstruction;
Each refractive interface and amphiblestroid form and range information is obtained according to the boundary information extracted.Comprise the curvature of anterior surface of cornea 1, the curvature of posterior surface of cornea 2, the curvature of anterior surface of lens 3, the curvature of crystalline lens rear surface 4, corneal central thickness, anterior chamber depth, lens thickness and vitreous chamber thickness.
Then utilize optical path-tracing method, as ZEMAX optical path-tracing simulation softward, obtain the route 6 of the central optical power of boresight direction and become the peripheral refraction power route 7 of unspecified angle with the described optical axis.
Calculate the described peripheral refraction power of described unspecified angle and the difference of described central optical power, obtain peripheral refraction value thus.
In order to obtain the imaging of larger pupil scope, can imaging after mydriasis to experimenter, do not affect the measurement of peripheral refraction.The method only needs the OCT image of the full eye of the disposable acquisition of high-resolution OCT system by full eye imaging, and follow-up realization can pass through software processes, the shortcomings such as the measurement point avoiding existing peripheral refraction measuring method is many, speed slow, location inaccuracy.
Claims (6)
1., based on a peripheral refraction measuring method for OCT technology, described method comprises:
Utilize OCT system to carry out one-time imaging to intraocular refracting media and retina, obtain OCT image;
Image processing software is utilized to analyze described OCT image, to obtain each refractive interface and amphiblestroid form and range information;
Utilize optical path-tracing method, obtain the central optical power of boresight direction and become the peripheral refraction power of unspecified angle with the described optical axis;
Calculate the described peripheral refraction power of described unspecified angle and the difference of described central optical power, obtain peripheral refraction value thus,
Described OCT system is made up of anterior ocular segment depth scan OCT and oculi posterior segment OCT, described anterior ocular segment depth scan OCT can corneal and whole crystalline lens imaging, described oculi posterior segment OCT can to retina image-forming, by the OCT image of synchronous scanning, sample eye more complete in double focusing probe, image acquisition and image integration technical limit spacing.
2., according to the peripheral refraction measuring method based on OCT technology described in claim 1, wherein said OCT system is the high-resolution depth scan OCT system of full eye imaging.
3., according to the peripheral refraction measuring method based on OCT technology described in claim 1, wherein said optical path-tracing method is realized by ZEMAX optical path-tracing simulation softward.
4. according to the peripheral refraction measuring method based on OCT technology described in claim 1, described OCT image is two dimensional image or 3-D view, described OCT image each refractive interface of clear display and retina.
5. the peripheral refraction measuring method based on OCT technology according to claim 1, described refracting media comprises cornea, anterior chamber and crystalline lens.
6. the peripheral refraction measuring method based on OCT technology according to any one of claim 1,2,3,4 or 5, wherein the method for image procossing comprises: first carry out noise reduction process to image; Adopt boundary extraction algorithm, the border of each organizational interface is extracted, if 3-D view, on the basis of Boundary Extraction, also needs to carry out image registration and three-dimensional reconstruction; Form and the range information at each interface is obtained according to the boundary information extracted.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310059943.7A CN103142210B (en) | 2013-02-26 | 2013-02-26 | Peripheral refraction measuring method based on OCT technology |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310059943.7A CN103142210B (en) | 2013-02-26 | 2013-02-26 | Peripheral refraction measuring method based on OCT technology |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103142210A CN103142210A (en) | 2013-06-12 |
| CN103142210B true CN103142210B (en) | 2015-03-18 |
Family
ID=48540762
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310059943.7A Active CN103142210B (en) | 2013-02-26 | 2013-02-26 | Peripheral refraction measuring method based on OCT technology |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103142210B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103519781B (en) * | 2013-09-26 | 2015-06-17 | 澳门科技大学 | Method and device for eliminating reflected light at cornea center of anterior segment optical coherence tomographic image |
| CN104050664A (en) * | 2014-06-09 | 2014-09-17 | 杭州电子科技大学 | Method for classifying eye anterior chamber angle opening degrees in multi-feature mode based on OCT image |
| CN104688178B (en) * | 2015-03-05 | 2017-01-25 | 温州医科大学 | Keratectasia measurement method based on optical CT |
| CN104905763B (en) | 2015-06-18 | 2017-12-19 | 苏州四海通仪器有限公司 | The optometry equipment of measurable other center defocus |
| JP6699956B1 (en) * | 2019-01-16 | 2020-05-27 | 株式会社トプコン | Ophthalmic device |
| CN112120666A (en) * | 2020-10-14 | 2020-12-25 | 上海爱尔眼科医院有限公司 | Lens refractive power measuring and calculating method, device, equipment and storage medium |
| CN115553714A (en) * | 2021-07-02 | 2023-01-03 | 深圳盛达同泽科技有限公司 | Optometry equipment |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101019759A (en) * | 2007-03-14 | 2007-08-22 | 温州医学院 | Method of measuring eye axis length and live tissue structure thickness of animal |
| CN101229052A (en) * | 2007-01-23 | 2008-07-30 | 南开大学 | Amendment of wave aberration data in individual visualness-rectifying |
| CN101523270A (en) * | 2006-07-31 | 2009-09-02 | 眼科研究所 | Corneal and epithelial remodelling |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008148517A1 (en) * | 2007-06-04 | 2008-12-11 | Carl Zeiss Meditec Ag | Method for determining the power of an intraocular lens |
| EP2485009A1 (en) * | 2011-02-04 | 2012-08-08 | Haag-Streit Ag | Frequency domain OCT |
-
2013
- 2013-02-26 CN CN201310059943.7A patent/CN103142210B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101523270A (en) * | 2006-07-31 | 2009-09-02 | 眼科研究所 | Corneal and epithelial remodelling |
| CN101229052A (en) * | 2007-01-23 | 2008-07-30 | 南开大学 | Amendment of wave aberration data in individual visualness-rectifying |
| CN101019759A (en) * | 2007-03-14 | 2007-08-22 | 温州医学院 | Method of measuring eye axis length and live tissue structure thickness of animal |
Non-Patent Citations (2)
| Title |
|---|
| Accuracy of the reconstruction of the crystalline lens gradient index with optimization methods from Ray Tracing and Optical Coherence Tomography data;Alberto de Castro et al.;《OPTICS EXPRESS》;20110926;第19卷(第20期);全文 * |
| Small Animal Ocular Biometry using Optical Coherence Tomography;Marco Ruggeri et al.;《Proc. of SPIE》;20100303;第7550卷;第755016-1页第2段，第755016-2页第1段-755016-3页第1段 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103142210A (en) | 2013-06-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103142210B (en) | Peripheral refraction measuring method based on OCT technology | |
| Hernández-Camarena et al. | Repeatability, reproducibility, and agreement between three different Scheimpflug systems in measuring corneal and anterior segment biometry | |
| Nakagawa et al. | Higher-order aberrations due to the posterior corneal surface in patients with keratoconus | |
| US6234631B1 (en) | Combination advanced corneal topography/wave front aberration measurement | |
| CN108814544B (en) | Anterior segment morphology analysis method | |
| Nowakowski et al. | Investigation of the isoplanatic patch and wavefront aberration along the pupillary axis compared to the line of sight in the eye | |
| JP2022526867A (en) | Eye examination | |
| CN111110184A (en) | Peripheral retinal aberration optical measurement system based on Hartmann-Shack wavefront aberration measuring instrument | |
| CN102467612A (en) | Method for constructing individual eye optical model | |
| CN103745257A (en) | Cone-cell density calculation method based on image identification | |
| CN102525402A (en) | Optical system and optometry method of computer optometer | |
| US20040021826A1 (en) | Combination advanced corneal topography/wave front aberration measurement | |
| Li et al. | Research on calculation of the IOL tilt and decentration based on surface fitting | |
| CN207168484U (en) | Binocular fundus camera imaging optical system | |
| CN202568203U (en) | Optical system of computerized subjective refractometer | |
| US9665771B2 (en) | Method and apparatus for measuring aberrations of an ocular optical system | |
| Heilman et al. | Peripheral defocus of the monkey crystalline lens with accommodation in a lens stretcher | |
| CN115336967A (en) | Method for obtaining retinal morphology | |
| CN103767675A (en) | Imaging corneal curvimeter optical system | |
| Jagini et al. | Utility of theoretical Hirschberg ratio for gaze position calibration | |
| Zhang et al. | Comparison of corneal curvature parameters obtained from two different instruments—Pentacam and VX120 | |
| CN108577801A (en) | Portable stereoscopic is imaged fundus camera optical system | |
| CN113331782B (en) | Computer optometry instrument | |
| Williams | Computational Methods to Quantify Human Lens Shape and Optical Properties Using Laser Ray Tracing and Optical Coherence Tomography | |
| Carvalho et al. | Quantitative comparison of different-shaped wavefront sensors and preliminary results for defocus aberrations on a mechanical eye |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Yuan Yimin Inventor after: Lv Fan Inventor after: Shen Meixiao Inventor after: Zhu Dexi Inventor before: Yuan Yiming Inventor before: Lv Fan Inventor before: Shen Meixiao Inventor before: Zhu Dexi |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: YUAN YIMING LV FAN SHEN MEIXIAO ZHU DEXI TO: YUAN YIMIN LV FAN SHEN MEIXIAO ZHU DEXI |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |