CN103110837B - Preparation method of traditional Chinese medicine for treating internal heat toxicity type parenchymatous keratitis - Google Patents

Preparation method of traditional Chinese medicine for treating internal heat toxicity type parenchymatous keratitis Download PDF

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CN103110837B
CN103110837B CN201310050329.4A CN201310050329A CN103110837B CN 103110837 B CN103110837 B CN 103110837B CN 201310050329 A CN201310050329 A CN 201310050329A CN 103110837 B CN103110837 B CN 103110837B
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张翠芳
王爱华
张霞
张其红
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Zhang Cuifang
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Abstract

The invention provides a preparation method of a traditional Chinese medicine for treating internal heat toxicity type parenchymatous keratitis, and belongs to the technical field of preparation methods of traditional Chinese medicines. Currently, sulfonamides and antibiotics are generally adopted to treat internal heat toxicity type parenchymatous keratitis, but has the defect of easily causing adverse reactions to a patient. The preparation method is characterized by comprising the following steps of immersing the following traditional Chinese medicines in water, namely iron holly bark, starwort root, creeping oxalis, buckthorn, veronicastrum herb, daghestan sweet clover herb, coffee senna seed, common alstonia bark leaf, lophatherum gracile, mungbean, dandelion, red-spotted stonecrop, shortstalk slimptop meadowrue root, breynia fruticosa, small-leaved desmodium, wintercherry, fresh golden thread, uniflower swisscentaury root, olive, taenitis carnosa mett, creeping rostellularia herb, gamboge, potentilla discolor, selfheal, feather cockscomb seed, butterflybush flower, pipewort, scouring rush, chrysanthemum, mint, cicada slough, bat faece, polygonum orientale and liquorice; decocting with slow fire; and filtering and removing slag to obtain decoction, which is the traditional Chinese medicine for treating internal heat toxicity type parenchymatous keratitis. The traditional Chinese medicine has the advantages of short course of treatment and high cure rate. Monarch, minister, assistant and guide medicines are compatible.

Description

A kind of Chinese medicinal preparation method of accumulateing type parenchymatous keratitis in pyretic toxicity for the treatment of
Technical field
The present invention relates to Chinese medicinal preparation method technical field, more specifically a kind of Chinese medicinal preparation method of accumulateing type parenchymatous keratitis in pyretic toxicity for the treatment of.
Background technology
In treatment pyretic toxicity, accumulate type parenchymatous keratitis at present, generally adopt sulfonamides and antibiotics.1. adopt sulfamethoxazole patient to cause gastrointestinal reaction, crystalluria, hematuria, erythra, medicine heat and leukopenia.2. carbenicillin: can occur various types of allergy.After heavy dose of administration, can cause neural poison reaction, pulmonary edema; During medication, can occur that transience ammonia enzyme raises and granulocytopenia.3. apply kanamycin: all toxic to acoustic nerve and kidney, the former shows as tinnitus, auditory dysesthesia, even permanent deafness, the latter shows as albuminuria, cylinderuria etc.4. adopt penicillin: with before must do skin test, positive forbidding.Because allergy, particularly anaphylactic shock easily occur penicillin, (the most dangerous anaphylactic shock, can occur in and do tuerculoderma at that time, only a few can occur in the process of continuous use, the latter claims tardy raw anaphylactic shock), as rescued not in time, can threat to life.
Summary of the invention
For overcoming above-mentioned shortcoming, the object of the invention is to invent a kind of Chinese medicinal preparation method of accumulateing type parenchymatous keratitis in pyretic toxicity for the treatment of.
Parenchymatous keratitis is a kind of chronic wind wheel illness, and motherland's medical science is called interstitial keratitis.This disease state of an illness is comparatively complicated, recovers extremely slow, often pass through the several months, or the more time just can alleviate, general adult two orders of suffering from more, the course of disease is longer, child suffers from an order more, recovers comparatively fast, to be with the passing of time easy to leave over white macula, vision is subject to obstacle.
Etiology and pathogenesis: primary disease is owing to usually having a liking for the hot savoury of food, and heat is accumulate in interior, attacks in order on " heat very fire ", " fire very malicious ", pyretic toxicity, and the strongly fragrant resistance of meridians is stopped up stagnant obstructedly, forms this card.
Clinical manifestation: white of the eye is micro-red, and corneal opacity is in blocks, develops slowlyer, or evening is light early heavy, flushed complexion, and eye is many not bitterly or hypodynia, deep and forceful pulse.
Its technical scheme is: get Cortex Ilicis Rotundae 9 weight portions, Radix Stellariae 9 weight portions, Herba Oxalidis Corniculatae 6 weight portions, Fructus rhamni (Rhamnus davurica Pall.) 6 weight portions, Herba veronicastri villosuli 6 weight portions, Herba Meliloti Suaveolentis 3 weight portions, Herba cassiae occidentalis 6 weight portions, Cortex Alstoniae scholaris 6 weight portions, Herba Lophatheri 12 weight portions, Semen phaseoli radiati 18 weight portions, Herba Taraxaci 18 weight portions, Herba hylotelephii erythrosticti 3 weight portions, Radix Thalictri brevipedis 6 weight portions, Folium et cacumen Breyniae Fruticosae 9 weight portions, Herba desmodii microphylli 6 weight portions, Calyx seu fructus physalis 3 weight portions, Rhizoma jeffersoniae dubiae 6 weight portions, Radix Rhapontici 9 weight portions, Fructus Canarii albi 9 weight portions, Lemmaphyllum microphullum Presl 6 weight portions, Herba Rostellulariae 9 weight portions, Resina garciniae 6 weight portions, Herba Potentillae Discoloris 12 weight portions, Spica Prunellae 6 weight portions, Semen Celosiae 6 weight portions, Flos Buddlejae 9 weight portions, Flos Eriocauli 3 weight portions, Herba Equiseti Hiemalis 3 weight portions, Flos Chrysanthemi 6 weight portions, Herba Menthae 9 weight portions, Periostracum Cicadae 6 weight portions, Faeces Vespertilionis 3 weight portions, Fructus Polygoni Orientalis 9 weight portions and Radix Glycyrrhizae 9 weight portions, put into 1800 ml waters by above 34 taste Chinese medicines, soaks 35 minutes, then fried 30 minutes of slow fire, filter and remove residue, 360 milliliters of the liquid of boiling medicine altogether, fried medicinal liquid is the Chinese medicine that accumulates type parenchymatous keratitis in treatment pyretic toxicity.
The advantage of this invention is: our 35 taste Chinese medicines, in pharmacy, all can buy, and to make simply, the herb liquid toxic and side effects of making is little, short treating period, cure rate is high.Monarch, just right.In the time of application Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided Western medicine sulphonamides, antibiotics to cause.Cortex Ilicis Rotundae, Radix Stellariae, Herba Oxalidis Corniculatae, Fructus rhamni (Rhamnus davurica Pall.), Herba veronicastri villosuli, Herba Meliloti Suaveolentis, Herba cassiae occidentalis, Cortex Alstoniae scholaris, Herba Lophatheri, Semen phaseoli radiati, Herba Taraxaci, Herba hylotelephii erythrosticti, Radix Thalictri brevipedis, Folium et cacumen Breyniae Fruticosae, Herba desmodii microphylli, Calyx seu fructus physalis, Rhizoma jeffersoniae dubiae, Radix Rhapontici, Fructus Canarii albi, Lemmaphyllum microphullum Presl, Herba Rostellulariae, Resina garciniae, Herba Potentillae Discoloris, above 23 taste medical instruments have the effect of heat clearing and damp drying, eliminating fire and detoxication, cooling blood for hemostasis, reducing swelling and alleviating pain, clearing away heat-damp and promoting diuresis, eliminating stasis to stop pain.In treatment pyretic toxicity, accumulate in the process of type parenchymatous keratitis, play primary treatment effect, therefore be monarch drug.Spica Prunellae, Semen Celosiae, Flos Buddlejae, Flos Eriocauli, Herba Equiseti Hiemalis, Flos Chrysanthemi, Herba Menthae, the above 8 taste medical instruments of Periostracum Cicadae have the effect of the eliminating stagnation of relieving inflammation or internal heat, liver heat removing and eyesight improving nebula removing, blood pressure lowering, heat clearing away nourishing the liver.In treatment pyretic toxicity, accumulate in the process of type parenchymatous keratitis, can assist principal agent performance therapeutical effect, therefore be ministerial drug.Faeces Vespertilionis, Fructus Polygoni Orientalis have the effect of enriching yin and nourishing kidney, liver heat removing and eyesight improving, promoting blood circulation to remove stagnancy, and all medicines of the energy rate focus of going directly, therefore be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate again the toxicity of all medicines, therefore for making medicine.Cortex Ilicis Rotundae, Radix Stellariae, Herba Oxalidis Corniculatae, Fructus rhamni (Rhamnus davurica Pall.), Herba veronicastri villosuli, Herba Meliloti Suaveolentis, Herba cassiae occidentalis, Cortex Alstoniae scholaris, Herba Lophatheri, Semen phaseoli radiati, Herba Taraxaci, Herba hylotelephii erythrosticti, Radix Thalictri brevipedis, Folium et cacumen Breyniae Fruticosae, Herba desmodii microphylli, Calyx seu fructus physalis, Rhizoma jeffersoniae dubiae, Radix Rhapontici, Fructus Canarii albi, Lemmaphyllum microphullum Presl, Herba Rostellulariae, Resina garciniae, Herba Potentillae Discoloris, Spica Prunellae, Semen Celosiae, Flos Buddlejae, Flos Eriocauli, Herba Equiseti Hiemalis, Flos Chrysanthemi, Herba Menthae, Periostracum Cicadae, Faeces Vespertilionis, Fructus Polygoni Orientalis, Radix Glycyrrhizae.This 34 taste medicine compatibility is applied, and jointly plays the effect of heat clearing and damp drying, eliminating fire and detoxication, cooling blood for hemostasis, reducing swelling and alleviating pain, clearing away heat-damp and promoting diuresis, suppressing the hyperactive liver improving eyesight, nebula removing, the improving eyesight of relieving inflammation or internal heat.Monarch, compatibility is proper, is the optimum formula that accumulates type parenchymatous keratitis in treatment pyretic toxicity.Cortex Ilicis Rotundae: hardship, cold.Enter lung, liver, large intestine channel.Heat-clearing and toxic substances removing, heat clearing and damp drying, reducing swelling and alleviating pain.Radix Stellariae: sweet, bitter, be slightly cold.Enter liver, stomach warp.Reducing the asthenic fever, asthenia, clearing heat in indigestion.Herba Oxalidis Corniculatae: sour, micro-puckery, cold.Enter lung, stomach warp.Clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating, cooling blood for hemostasis.Fructus rhamni (Rhamnus davurica Pall.): sweet, bitter, cold.Enter liver,kidney,spleen three warps.Clearing away heat-damp and promoting diuresis, invigorating the spleen for dissipating phlegm.Herba veronicastri villosuli: pungent, bitter, cold.Enter liver, lung, kidney three warps.Heat-clearing and toxic substances removing, the capable water of dampness removing, eliminating stasis to stop pain.Herba Meliloti Suaveolentis: pungent, bitter, cool, nontoxic.Enter liver, spleen, stomach warp.Heat-clearing and toxic substances removing, heat clearing and damp drying, inducing diuresis for treating stranguria syndrome.Herba cassiae occidentalis: hardship, cold.Enter lung, liver, stomach warp.Relieving cough and asthma, liver heat removing and eyesight improving, stomach function regulating help digestion, subduing swelling and detoxicating, inducing diuresis for treating stranguria syndrome, relieving constipation by purgation.Cortex Alstoniae scholaris: bitter, light, cold.Enter lung, Liver Channel.Heat-clearing and toxic substances removing, hemostasia and detumescence.Herba Lophatheri: sweet, light, cold.Enter the heart, stomach, kidney, small intestine meridian.Relieving restlessness, heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, Qinghua heat-phlegm clear away heart-fire.Semen phaseoli radiati: sweet, cold.Enter the heart, spleen, stomach, lung meridian.Heat-clearing and toxic substances removing, relieve heat and thirst, inducing diuresis to remove edema, QI invigorating skin moistening, the thick intestinal of clearing stomach.Herba Taraxaci: bitter, sweet, cold.Enter liver, stomach warp.Heat-clearing and toxic substances removing, clearing away heat-damp and promoting diuresis, tonneau urine.Herba hylotelephii erythrosticti: bitter, sour, cold.Enter the heart, liver, kidney, large intestine channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis.Radix Thalictri brevipedis: hardship, cold, nontoxic.Enter lung, the heart, spleen, large intestine channel.Clearing away damp-heat, heat-clearing and toxic substances removing, lowering the adverse-rising QI to subdue asthma.Folium et cacumen Breyniae Fruticosae: hardship, cold.Enter large intestine, Liver Channel.Heat-clearing and toxic substances removing, removing stasis to stop bleeding.Herba desmodii microphylli: sweet, bitter, cold.Enter spleen, stomach, the heart, kidney channel.Heat-clearing and toxic substances removing, invigorating spleen to remove dampness, clearing away heat-damp and promoting diuresis.Calyx seu fructus physalis: sour, bitter, cold.Enter lung, spleen channel.Clearing heat, eliminating phlegm, relieving cough, heat-clearing and toxic substances removing, treatment edema.Rhizoma jeffersoniae dubiae: hardship, cold.Enter the heart, liver, stomach, large intestine channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis, treatment diarrhea due to damp-heat.Radix Rhapontici: bitter, salty, cold.Enter stomach, large intestine two warps.Heat-clearing and toxic substances removing, detumescence and apocenosis, treatment galactozemia, logical muscle arteries and veins, cooling blood for hemostasis.Fructus Canarii albi: sweet, puckery, sour, flat.Enter lung, stomach two warps.Clearing away lung-heat to relieve cough, heat-clearing and toxic substances removing sore-throat relieving, promoting the production of body fluid to quench thirst, removing toxic substances dysentery relieving, checking hyperfunction of the liver for relieving convulsion, solution Trionyx sinensis Wiegmann poison.Lemmaphyllum microphullum Presl: pungent, sweet, micro-hardship, cool.Enter lung, spleen, stomach, kidney four warps.Heat-clearing and toxic substances removing, cooling blood for hemostasis, nourishing the lung to arrest cough, expelling wind and dampness, clearing away heat-damp and promoting diuresis, treatment lithangiuria, acute toothache, fulminant dysentery.Herba Rostellulariae: salty, micro-pungent, micro-hardship, cold.Enter liver, gallbladder, spleen three warps.Heat-clearing and toxic substances removing, dampness removing stagnant, the promoting blood circulation and stopping pain that disappears.Resina garciniae: sour, puckery, cold.Very toxic.Enter spleen, stomach, large intestine three warps.Removing toxic substances and promoting subsidence of swelling, astringing to arrest bleeding, parasite killing are treated skin ulcer.Herba Potentillae Discoloris: sweet, micro-hardship, flat (cooler).Enter liver, stomach, large intestine three warps.Heat-clearing and toxic substances removing, cooling blood for hemostasis.Spica Prunellae: bitter, acrid, cold.Enter liver, gallbladder meridian.Eliminating stagnation, removing heat from the liver to lower the high blood pressure relieve inflammation or internal heat.Semen Celosiae: hardship, is slightly cold.Enter Liver Channel.Liver heat removing and eyesight improving nebula removing, blood pressure lowering.Flos Buddlejae: sweet, be slightly cold.Enter Liver Channel.Heat clearing away nourishing the liver, improving acuity of vision and removing nebula.Flos Eriocauli: sweet, flat.Enter liver, stomach warp.Removing nebula to improve visual acuity, dispelling wind and heat pathogens.Herba Equiseti Hiemalis: sweet, bitter, flat.Enter lung, liver, gallbladder meridian.Dispelling wind heat, suppressing the hyperactive liver improving eyesight.Flos Chrysanthemi: be slightly cold; Sweet, bitter; Return lung, Liver Channel.Dispelling wind and heat pathogens, suppressing the hyperactive liver improving eyesight.Herba Menthae: cool; Pungent; Return lung, Liver Channel.Dispelling wind-heat, refresh oneself, rash.Periostracum Cicadae: cold; Sweet; Return lung, Liver Channel.Loose wind heat extraction, sore-throat relieving, rash, nebula removing, relieving convulsion.Faeces Vespertilionis: pungent, cold.Enter Liver Channel, liver heat removing and eyesight improving.Fructus Polygoni Orientalis: pungent, bitter, cold.Enter Liver Channel.Liver heat removing and eyesight improving, promoting blood circulation to remove stagnancy.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.
The specific embodiment
Get Cortex Ilicis Rotundae 9g, Radix Stellariae 9g, Herba Oxalidis Corniculatae 6g, Fructus rhamni (Rhamnus davurica Pall.) 6g, Herba veronicastri villosuli 6g, Herba Meliloti Suaveolentis 3g, Herba cassiae occidentalis 6g, Cortex Alstoniae scholaris 6g, Herba Lophatheri 12g, Semen phaseoli radiati 18g, Herba Taraxaci 18g, Herba hylotelephii erythrosticti 3g, Radix Thalictri brevipedis 6g, Folium et cacumen Breyniae Fruticosae 9g, Herba desmodii microphylli 6g, Calyx seu fructus physalis 3g, Rhizoma jeffersoniae dubiae 6g, Radix Rhapontici 9g, Fructus Canarii albi 9g, Lemmaphyllum microphullum Presl 6g, Herba Rostellulariae 9g, Resina garciniae 6g, Herba Potentillae Discoloris 12g, Spica Prunellae 6g, Semen Celosiae 6g, Flos Buddlejae 9g, Flos Eriocauli 3g, Herba Equiseti Hiemalis 3g, Flos Chrysanthemi 6g, Herba Menthae 9g, Periostracum Cicadae 6g, Faeces Vespertilionis 3g, Fructus Polygoni Orientalis 9g and Radix Glycyrrhizae 9g, above 34 taste medicines are put into 1800 ml waters together, soak 35 minutes, then fried 30 minutes of slow fire, filter and remove residue, fried medicinal liquid is the Chinese medicine that accumulates type parenchymatous keratitis in treatment pyretic toxicity.Boil medicine altogether 360 milliliters of liquid, when accumulateing the client need treatment of type parenchymatous keratitis in pyretic toxicity, making fluid temperature is 36 ℃, each 120 milliliters, oral, every day three times, within 2nd, be a course for the treatment of, if symptom is still deposited, then took for second course for the treatment of, so that recovery from illness.
In 299 routine pyretic toxicity, accumulate in type parenchymatous keratitis patient, women's 182 examples, account for 60.87%; Male's 117 examples, account for 39.13%.Women is more than male.
Figure 624905DEST_PATH_IMAGE005
In table four, 299 routine pyretic toxicity, accumulate type parenchymatous keratitis patient treatment front and back information slip
Figure 65376DEST_PATH_IMAGE007

Claims (1)

1. treat the Chinese medicinal preparation method of accumulateing type parenchymatous keratitis in pyretic toxicity for one kind, it is characterized in that: get 9 grams of Cortex Ilicis Rotundaes, 9 grams of Radix Stellariaes, 6 grams of Herba Oxalidis Corniculataes, 6 grams of Fructus rhamni (Rhamnus davurica Pall.)s, 6 grams of Herba veronicastri villosulis, 3 grams of Herba Meliloti Suaveolentiss, 6 grams of Herba cassiae occidentaliss, 6 grams of Cortex Alstoniae scholariss, 12 grams of Herba Lophatheris, 18 grams, Semen phaseoli radiati, 18 grams of Herba Taraxacis, 3 grams of Herba hylotelephii erythrostictis, 6 grams of Radix Thalictri brevipediss, 9 grams of Folium et cacumen Breyniae Fruticosae, 6 grams of Herba desmodii microphyllis, 3 grams of Calyx seu fructus physaliss, 6 grams of Rhizoma jeffersoniae dubiaes, 9 grams of Radix Rhapontici, 9 grams of Fructus Canarii albis, 6 grams of Lemmaphyllum microphullum Presls, 9 grams of Herba Rostellulariaes, 6 grams of Resina garciniaes, 12 grams of Herba Potentillae Discoloris, 6 grams of Spica Prunellaes, 6 grams of Semen Celosiae, 9 grams of Flos Buddlejaes, 3 grams of Flos Eriocaulis, 3 grams of Herba Equiseti Hiemalis, 6 grams of Flos Chrysanthemis, 9 grams of Herba Menthaes, 6 grams of Periostracum Cicadaes, 3 grams of Faeces Vespertilioniss, 9 grams, 9 grams of Fructus Polygoni Orientaliss and Radix Glycyrrhizae, above 34 taste Chinese medicines are put into 1800 ml waters, soak 35 minutes, then fried 30 minutes of slow fire, filter and remove residue, boil medicine altogether 360 milliliters of liquid, fried medicinal liquid is the Chinese medicine that accumulates type parenchymatous keratitis in treatment pyretic toxicity.
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