CN103107060A - Ionic migration spectrum with radio frequency confinement function - Google Patents
Ionic migration spectrum with radio frequency confinement function Download PDFInfo
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- CN103107060A CN103107060A CN2013100192327A CN201310019232A CN103107060A CN 103107060 A CN103107060 A CN 103107060A CN 2013100192327 A CN2013100192327 A CN 2013100192327A CN 201310019232 A CN201310019232 A CN 201310019232A CN 103107060 A CN103107060 A CN 103107060A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/622—Ion mobility spectrometry
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Abstract
An ionic migration spectrum with a radio frequency confinement function comprises ion sources (1), a drift tube (2), radio-frequency electrodes (3) and a detector (4). Radio-frequency voltage opposite in phase is applied onto adjacent electrodes on the drift tube of the ionic migration spectrum, the collision probability of ions at the positions, close to the electrodes, is increased through the radio-frequency voltage, the migration path of the ions is confined in a central line of the drift tube, and therefore the sensitivity and the resolution ratio of the ionic migration spectrum are improved.
Description
Technical field
The present invention relates to the ionic migration spectrometer technical field, be specifically related to a kind of ion mobility spectrometry that possesses the radio frequency confinement function.
Background technology
Ion mobility spectrometry (ion mobility spectrometry, IMS) also claims ion mobility spectrometry, is a kind of new gas phase separation and the detection technique that occurs at 20 century 70s.The separation that it carries out ion with the difference of ion drift time is qualitative, and is highly sensitive because it is simple in structure, can use under atmospheric pressure and normal temperature and the trace that is widely used in some VOCs is surveyed.
IMS usually amplifies collection by transference tube, air-channel system, sampling and sampling system, ion gate control system, high voltage power supply, temperature heating control circuit, signal and data handling system seven parts form.Brought into the ionization reaction district by carrier gas when sample after, a series of ionization reaction and ion-molecule reaction occur in carrier gas molecules and sample molecule under ionogenic effect, form various product ions.Under the ordering about of electric field, the ion gate that these ions are opened by periodicity enters the drift region.In the process that the neutral elegant gas molecule with adverse current constantly collides, migration rate is different separately in electric field due to these ions, makes different ions be separated, and successively arrives collector detected.
But when ion flew in the migration area, ion disperseed gradually along with the prolongation of flight time, a lot of ions can be diffused on migration area electrode on every side, and, due to the dispersion of ion, make also disunity of time that ion arrives detector, reduced greatly sensitivity and the resolution of instrument.
Summary of the invention
The defective that exists in order to overcome prior art the purpose of this invention is to provide a kind of ion mobility spectrometry that possesses the radio frequency confinement function, and it utilizes rf electric field to retrain Ion paths in ion mobility spectrometry, reaches the purpose that improves sensitivity and resolution.
The invention provides a kind of ion mobility spectrometry that possesses the radio frequency confinement function, comprise ion source, drift tube, radio-frequency power supply and detector.Apply the radio-frequency voltage of single spin-echo on the adjacent electrode on the drift tube of ion mobility spectrometry, by radio-frequency voltage, ion is strengthened in the position collision probability near electrode, the migration path of ion is constrained on the center line of drift tube, realizes improving the purpose of sensitivity and resolution.
The ion mobility spectrometry that possesses the radio frequency confinement function provided by the invention, the described radio-frequency (RF) field frequency that applies the radio frequency electrode of radio-frequency voltage are that hundreds of KHz arrives some MHz, the voltage (V of interchange or pulse signal
pp) be 0-300V.The described mode that applies that applies radio-frequency voltage is adjacent electrode single spin-echo, and the electrode phase place at interval is identical.
The invention has the beneficial effects as follows: the present invention can utilize rf electric field that the migration path of ion is constrained on the center line of migration tube, reduces because ion is diffused on electrode or arrives the caused sensitivity of detector time disunity and decrease resolution.
Description of drawings
Fig. 1 is a kind of structural representation that possesses the ion mobility spectrometry of radio frequency confinement function of the present invention; (1) be ion source, (2) are drift tube, and (3) are radio frequency electrode, and (4) are detector;
Fig. 2 be computer simulation there is no the radio frequency confinement field time (a) and the difference of (b) ion traveling locus when the radio frequency confinement field is arranged.
Embodiment
Below in conjunction with accompanying drawing, the present invention is described in further details.
As shown in Figure 1, a kind of ion mobility spectrometry that possesses the radio frequency confinement function of the present invention is made of drift tube electrode, detector, ion source and radio-frequency power supply.Ion enters the drift region by electronic gate after being produced by ion source, due to the constraint that is subject to rf electric field, migration path is concentrated on the center line of drift tube, finally arrives detector and detects.The frequency of radiofrequency field is that hundreds of KHz is to some MHz, V
ppBe 0 ~ 300V.The mode that applies of radio-frequency power supply is adjacent electrode single spin-echo, and the spaced electrode phase place is identical.
Claims (3)
1. ion mobility spectrometry that possesses the radio frequency confinement function, comprise ion source, drift tube, radio frequency electrode and detector, it is characterized in that: the radio-frequency voltage that has applied single spin-echo on the adjacent electrode of the drift tube of conventional ion migration spectrum, by radio-frequency voltage, ion is strengthened in the position collision probability near electrode, the migration path of ion is constrained on the center line of drift tube, and then has improved resolution and sensitivity.
2. according to the described ion mobility spectrometry that possesses the radio frequency confinement function of claim 1, it is characterized in that: the described radio-frequency (RF) field frequency that applies the radio frequency electrode of radio-frequency voltage is that hundreds of KHz arrives some MHz, the voltage V of interchange or pulse signal
ppBe 0-300V.
3. according to the described ion mobility spectrometry that possesses the radio frequency confinement function of claim 1, it is characterized in that: the described mode that applies that applies radio-frequency voltage is adjacent electrode single spin-echo, and the electrode phase place at interval is identical.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013100192327A CN103107060A (en) | 2013-01-18 | 2013-01-18 | Ionic migration spectrum with radio frequency confinement function |
| PCT/CN2013/000638 WO2014110698A1 (en) | 2013-01-18 | 2013-05-30 | Ion mobility spectrometer having radio frequency constraint function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013100192327A CN103107060A (en) | 2013-01-18 | 2013-01-18 | Ionic migration spectrum with radio frequency confinement function |
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| CN103107060A true CN103107060A (en) | 2013-05-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2013100192327A Pending CN103107060A (en) | 2013-01-18 | 2013-01-18 | Ionic migration spectrum with radio frequency confinement function |
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| CN (1) | CN103107060A (en) |
| WO (1) | WO2014110698A1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014110698A1 (en) * | 2013-01-18 | 2014-07-24 | 中国科学院大连化学物理研究所 | Ion mobility spectrometer having radio frequency constraint function |
| CN105612422A (en) * | 2013-08-23 | 2016-05-25 | 史密斯探测-沃特福特有限公司 | Ion modification |
| CN112288845A (en) * | 2020-09-18 | 2021-01-29 | 中国电建集团河北省电力勘测设计研究院有限公司 | Rapid three-dimensional modeling method for thermal control instrument |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090057546A1 (en) * | 2005-02-14 | 2009-03-05 | Micromass Uk Limited | Mass spectrometer |
| CN101606220A (en) * | 2006-11-07 | 2009-12-16 | 塞莫费雪科学（不来梅）有限公司 | Ion transfer arrangement |
| CN102592940A (en) * | 2007-12-27 | 2012-07-18 | 同方威视技术股份有限公司 | Ion migration spectrometer and method thereof |
| CN102723254A (en) * | 2012-06-20 | 2012-10-10 | 清华大学 | Focusing device and method of flat high-field asymmetric waveform ion mobility spectrometer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103107060A (en) * | 2013-01-18 | 2013-05-15 | 中国科学院大连化学物理研究所 | Ionic migration spectrum with radio frequency confinement function |
-
2013
- 2013-01-18 CN CN2013100192327A patent/CN103107060A/en active Pending
- 2013-05-30 WO PCT/CN2013/000638 patent/WO2014110698A1/en active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090057546A1 (en) * | 2005-02-14 | 2009-03-05 | Micromass Uk Limited | Mass spectrometer |
| CN101606220A (en) * | 2006-11-07 | 2009-12-16 | 塞莫费雪科学（不来梅）有限公司 | Ion transfer arrangement |
| CN102592940A (en) * | 2007-12-27 | 2012-07-18 | 同方威视技术股份有限公司 | Ion migration spectrometer and method thereof |
| CN102723254A (en) * | 2012-06-20 | 2012-10-10 | 清华大学 | Focusing device and method of flat high-field asymmetric waveform ion mobility spectrometer |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014110698A1 (en) * | 2013-01-18 | 2014-07-24 | 中国科学院大连化学物理研究所 | Ion mobility spectrometer having radio frequency constraint function |
| CN105612422A (en) * | 2013-08-23 | 2016-05-25 | 史密斯探测-沃特福特有限公司 | Ion modification |
| US10453665B2 (en) | 2013-08-23 | 2019-10-22 | Smiths Detection-Watford Limited | Ion modification |
| CN105612422B (en) * | 2013-08-23 | 2020-02-07 | 史密斯探测-沃特福特有限公司 | Ion modification |
| US10910207B2 (en) | 2013-08-23 | 2021-02-02 | Smiths Detection-Watford Limited | Ion modification |
| CN112288845A (en) * | 2020-09-18 | 2021-01-29 | 中国电建集团河北省电力勘测设计研究院有限公司 | Rapid three-dimensional modeling method for thermal control instrument |
| CN112288845B (en) * | 2020-09-18 | 2022-10-21 | 中国电建集团河北省电力勘测设计研究院有限公司 | Rapid three-dimensional modeling method for thermal control instrument |
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| Publication number | Publication date |
|---|---|
| WO2014110698A1 (en) | 2014-07-24 |
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Application publication date: 20130515 |