CN103104432A - Liquid chromatograph constant flow pump - Google Patents
Liquid chromatograph constant flow pump Download PDFInfo
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- CN103104432A CN103104432A CN2013100645295A CN201310064529A CN103104432A CN 103104432 A CN103104432 A CN 103104432A CN 2013100645295 A CN2013100645295 A CN 2013100645295A CN 201310064529 A CN201310064529 A CN 201310064529A CN 103104432 A CN103104432 A CN 103104432A
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Abstract
The invention relates to a liquid chromatograph, in particular to a liquid chromatograph constant flow pump, is used to liquid transmission in the liquid chromatograph, and belongs to the technical field of the liquid chromatograph. The liquid chromatograph constant flow pump is characterized by comprising an end face cam (15), a pair of paralleled plunger push rods (6), a thrust face of the end face cam (15) is of a smooth curve face shape, a cam curve is a liquid phase curve, opposite to the paralleled plunger push rods (6), and two end points of the cam curve respectively correspond to the pair of the paralleled plunger push rods (6). The end face cam (15) rotates and drives the pair of the paralleled plunger push rods (6) to push forwards in turns, and the pair of the paralleled plunger push rods (6) conducts reset motion driven by a spring (17) in turns. A pump body (17) corresponds to the pair of the paralleled plunger push rods (6) absorbs and pushes liquid in turns, and stable liquid flow is provided.
Description
Technical field
The present invention relates to a kind of liquid chromatograph, relate in particular to a kind of liquid chromatograph constant flow pump, be used for the fluid transport of liquid chromatograph, belong to the liquid chromatograph technical field.
Background technique
Liquid chromatograph is solution example to be carried out the instrument of compartment analysis, can be used for liquid or the solid sample that is dissolved in liquid carries out constant or microanalysis detects, be applicable to the extensively quality supervision Detection ﹠ Controling in industry such as agricultural chemicals, chemical fertilizer, medicine, epidemic prevention, environmental protection, commodity inspection, food, beverage, drinks, feed, petrochemical industry, coal, dyestuff, fine chemistry industry.Be widely used in fields such as organic chemical industry, organic synthesis, analytical chemistry, biochemistry, bioengineering, amino acid analysis, national defence scientific research teaching.
Liquid chromatograph mainly partly is comprised of inlet system, transfusion system, piece-rate system, detection system and data processing system etc., and wherein the capital equipment in transfusion system is high pressure constant flow pump.Liquid chromatograph is exported mobile phase by high pressure constant flow pump, and for example water or other liquid, promote sample solution and separate through chromatographic column, then enter the detection that detector carries out sample composition.High pressure constant flow pump be in liquid chromatograph one of crucial importance, relatively independent constituent element again.When the chromatographic column, stable flowing can reduce the diffusion effect of sample in post when mobile phase, and this is all favourable for the biologically active that improves resolution, sensitivity, detectability, maintenance sample etc.
Liquid chromatograph is all very important instrument for many departments of modern science and technology and national economy.But existing technical barrier of liquid chromatograph long-term existence, namely due to plunger rod motion match difference, the fluctuation of the delivery pressure of high pressure constant flow pump, thus cause flowed fluctuation, affected the analyzing and testing of sample.This technical barrier is long-term existence at home and abroad, has limited development and the application of liquid chromatograph.So obtain a kind of output liquid flow, pressure stability, the little high pressure constant flow pump that fluctuates is indispensable for the performance boost of liquid chromatogram instrument, the technical field that liquid chromatogram is related to has good promoting effect, and is significant for the quality of product that improves many industries.
Existing liquid chromatograph constant flow pump, mainly by two kinds of forms, the first form, referring to Fig. 1, Fig. 1 has showed a kind of 180 ° of constant flow pumps that single cam is parallel, comprises that is arranged on the two reciprocal conveying mechanism of cover and two pump heads 1 that cam 4 on camshaft 5,180 ° of symmetries are arranged on cam 4 both sides.Wherein back and forth conveying mechanism comprises two supporting rollers 3, connects plunger 2 and plunger push rod 6 on it.The other end of plunger push rod 6 stretches in the pump chamber of pump head 1, is provided with seal element between plunger push rod 6 and pump head 1.Pump head 1 is provided with inlet opening and the outage that is communicated with pump chamber respectively, and one-way valve is installed in inlet opening and outage separately.Two outages are connected in threeway 7 by pipeline, pump solution and are finally flowed out by the public outlet of threeway 7.On the basic circle excircle of cam 4, cam curve is arranged, supporting roller 3 contacts cooperation with the cam curve of cam 4.When driving mechanism band moving cam 4 rotated, supporting roller 3 rolled along the cam curve of cam 4, thereby the rotational motion of cam 4 was converted into the to-and-fro motion of plunger 2, and the interior volume size of pump chamber of pump head 1 is alternately changed.Advance, under the effect of two one-way valves in outage, plunger often makes a round trip, just extract a certain amount of liquid from inlet opening when the pump chamber volume increases, discharge a certain amount of liquid from outage when volume reduces, thereby complete continual and steady high pressure liquor charging function.Because of pump volume change at every turn all identical, therefore the total discharge that produces is constant.This 180 ° of single cams constant flow pump in parallel, because the two reciprocal conveying mechanism symmetries of cover are launched in the both sides of cam 4, make mechanism itself and matching used other mechanisms, relatively disperse on space layout as feed liquor, discharge opeing and analytical structure, each connecting pipeline etc., shared volume is large, cause the pump overall volume large, need very large containing space; Simultaneously, the fluid passage volume of pump itself is also large, and analysis when making instrument work, clean time and consumption all increase.Therefore its application for liquid chromatograph has significant limitation.
The second form, referring to Fig. 2, Fig. 3, for overcoming the defective of above-mentioned parallel-connected pumps, what the most generally use now is the double-cam parallel-connected pumps, referring to Fig. 2, double-cam parallel high voltage constant flow pump comprises a camshaft 5, be arranged on each cam 4 at this camshaft 5 two ends, and reciprocal conveying mechanism and two pump heads 1 of the two parallel installations of cover.Back and forth conveying mechanism coordinates with two cams 4 respectively.Reciprocal conveying mechanism wherein is identical with reciprocal conveying mechanism in 180 ° of single cam parallel-connected pumps shown in Figure 1, repeats no more.In the double-cam parallel-connected pumps, two cam 4 angles differ 180 °, and when wherein the plunger of a cover in reciprocal conveying mechanism promoted feed flow, the plunger in another set of reciprocal conveying mechanism promoted imbibition, the pump continuous liquid supply has been guaranteed in the two reciprocal conveying mechanism of cover alternations like this.This kind double-cam parallel-connected pumps two parallel homonymies at cam of the reciprocal conveying mechanism of cover launch, and have effectively reduced the space that mechanism itself and matching used other mechanisms occupy, and overall volume reduces, and has effectively overcome the defective of single lobe pump.But the employing of this pump two cams, two cams have an independently cam curve separately, therefore compensation between the two can't realize by Curve Design.Simultaneously, when both when mounted any deviation such as phase angle all can cause not mating of two cover conveying mechanisms motions, liquid output volume is fluctuateed.And this unmatched source is more, can derive from two cams installation, can derive from the installation of supporting roller, also can derive from the inhomogeneous of processing.Therefore the required precision to processing, installation is high, product is installed need to carry out fine adjustment, could obtain good transfusion precision and stability.Simultaneously, cost is high when using, stable differing.
In addition, the drive system of existing liquid chromatograph constant flow pump generally adopts the belt pulley control of slowing down, and the stability of belt pulley is not enough, and can not regulate speed ratio, cause constant flow pump flow velocity in use unstable, affected the testing precision of liquid chromatograph.
Summary of the invention
The technical issues that need to address of the present invention are: existing liquid chromatograph constant flow pump, or overall volume is excessive, needs very large containing space, thus cause the narrow limitation of application; Or need double-cam structure, can't carry out the track compensation by the design of cam curve again between double-cam, simultaneously, the design of double-cam structure, processing, assembling, debugging etc. all needs very high precision, and in actual the use, difficulty is higher, and stability is not good enough.In addition, the stability of belt pulley is not enough, and can not regulate speed ratio, causes constant flow pump flow velocity in use unstable, has affected the testing precision of liquid chromatograph.
The present invention is by the following technical solutions:
A kind of liquid chromatograph constant flow pump, comprise end cam 15, the plunger push rod 6 of pair of parallel, the thrust face of described end cam 15 are level and smooth curved surface shape, its cam curve is method phase surface curve with respect to described plunger push rod 6, and the two-end-point of cam curve is corresponding with a pair of plunger push rod 6 respectively; End cam 15 rotates, and drives a pair of plunger push rod 6 and promotes forward in turn, and a pair of plunger push rod 6 flows to the horizontal reset action at the drive lower whorl of spring 17; The pump housing 17 in turn imbibition corresponding with described a pair of plunger push rod 6, push away liquid, stable fluid flow is provided.
Further, also comprise supporting worm screw 11, worm gear 12, described worm screw 11 is driven by belt pulley 9 and rotates, and worm gear 12 rotates under the drive of worm screw 11, and described worm gear 12 is connected with worm-wheel shaft 14, and described worm-wheel shaft 14 is connected with the axle center of described end cam 15.
Further, described worm-wheel shaft 14 is provided with corresponding with it pair of bearings 13.
Further, described belt pulley 9 is connected with the output shaft of motor 8, and is rotated described motor 8 by motor 8 its drives.
Further, described motor 8 is stepper motors.
Characteristics of the present invention are: used normal plane simple curve end cam to drive high pressure constant flow pump, adopt a cam at the live axle end face, this cam has single cam curve on normal plane, therefore can realize the matched well in two sites on curve, there is not the installation poor location, two plungers of cam promotion can carry out the to-and-fro motion of matched well thus, have reduced the output fluctuation of constant flow pump, have realized that the liquid of regime flow is carried.
Beneficial effect of the present invention is:
1, the fluid pressure of output is stable, fluctuation is little;
2, the constant flow pump volume is little, I﹠ M is easy;
3, work is carried out continuously automatically, and is simple to operate;
4, component are few, not only reduced by a cam, can also save supporting roller, reduced cost of material.
5, simple in structure, assembling is simple, and low to the assembly precision requirement, operation stability is high, and maintenance cost is low.
6, the parts machining required precision reduces, and has reduced processing cost.
Description of drawings
Fig. 1 is the structural representation of liquid chromatograph constant flow pump of single cammingly of prior art.
Fig. 2 is the main TV structure schematic diagram of liquid chromatograph constant flow pump of the double cam-type of prior art.
Fig. 3 is the schematic top plan view of Fig. 2.
Fig. 4 is the structural representation of liquid chromatograph constant flow pump of the present invention.
Wherein, 1, pump head, 2, plunger, 3, supporting roller, 4, cam, 5, camshaft, 6, the plunger push rod, 7, threeway, 8, motor, 9, belt pulley, 10, drivign belt, 11, worm screw, 12, worm gear, 13, bearing, 14, worm-wheel shaft, 15, end cam, 16, the feed liquor one-way valve, 17, the pump housing, 18, spring, 19, the fluid one-way valve.
Embodiment
The present invention is further described below in conjunction with specific embodiment.
Referring to Fig. 4, a kind of high-pressure constant flow pump for single lobe of liquid chromatograph is comprised of stepper motor 8, drivign belt 10, bearing 13, worm screw 11, worm gear 12, worm-wheel shaft 14, end cam 15, plunger push rod 6, the pump housing 17 etc.The output shaft of stepper motor 8 drives drive pulley and rotates.Be connected with drivign belt 10 on drive pulley, drivign belt 10 drives driven pulley and rotates.Driven toothed pulley drives worm screw 11 and worm gear 12 rotates.Worm screw 11, worm gear 12 are worked in coordination, and worm-wheel shaft 14 is along with worm gear 12 rotates.Worm-wheel shaft 14 is provided with corresponding bearing 13, and end cam 15 is housed on the end face of worm-wheel shaft 14, and end cam 15 is normal plane simple curve cam.Worm gear curve on end cam 15 is reciprocating along with the rotation of worm-wheel shaft 14 alternately promotes two symmetrical plunger push rods 6.In the pump housing 17, the end of plunger push rod 6 is provided with spring 18, and the elastic force of spring 18 promotes plunger push rod 6 and does drawback movement.The liquid entrance of the pump housing 18 is respectively equipped with import one-way valve 16 and outlet one-way valve 19, makes liquid to flow forward and can not reflux.
Main points of the present invention are: promote the to-and-fro motion of two plungers with a normal plane simple curve cam.Mutual coupling during the to-and-fro motion of two plungers makes the liquid that all can pump in a flash equal volume in office, thereby realizes the mobile phase of output constant current.Because curve is single, therefore there is not the match penalties in assembly process.As long as cam rotates with a certain rotating speed under the driving of stepper motor, the flow that just can obtain setting accordingly, and appoint flashy flow value constant, namely Q/ Δ t is constant.By changing the rotating speed of stepper motor, namely can change the value of Q/ Δ t.
Due to the plunger rod motion that is two symmetries of the single curve promotion of same cam, so but two plunger rod matched well make the liquid volume, flow, the pressure that pump identical, avoided fluctuation.
Using method of the present invention is simple, and the control step motor gets final product practical function as long as start also, has guaranteed completing of task of the present invention.
Effect of the present invention is remarkable, due to it with two plungers of single curve controlled on same, so there is no assembly error.Existing constant flow pump both domestic and external substantially all adopts two face cams or two groups of noncircular gears to control respectively two plungers, unavoidably brings the phase place alignment error of two cams, causes the fluctuation of constant flow pump output volume and pressure.The present invention adopts the change of driving structure to realize the function of stable liquid output, greatly reduces the fluctuation of constant flow pump output flow and pressure.
The present invention's installation, simple to operate, reliable for effect has realized the stable output of highly pressurised liquid by structural change.And have the advantages such as pump volume is little, assembling is simple, reduced processing, production and maintenance cost.Because the liquid chromatograph application is extensive, the present invention has high marketing prospect and commercial value.
These are only the preferred embodiments of the present invention, the protection domain that is not intended to limit the present invention.To those of ordinary skill in the art, under total inventive concept of the present invention, various conversion can be arranged.For example method of the present invention simple curve cam of practising physiognomy is controlled the overall principle of two plunger rods motions, that does is equal to replacement, improvement etc., within all being included in protection scope of the present invention.
Claims (5)
1. liquid chromatograph constant flow pump is characterized in that:
Comprise end cam (15), the plunger push rod (6) of pair of parallel, the thrust face of described end cam (15) is level and smooth curved surface shape, and its cam curve is method phase surface curve with respect to described plunger push rod (6), and the two-end-point of cam curve is corresponding with a pair of plunger push rod (6) respectively;
End cam (15) rotates, and drives a pair of plunger push rod (6) and promotes forward in turn, and a pair of plunger push rod (6) flows to the horizontal reset action at the drive lower whorl of spring (17);
The pump housing (17) the in turn imbibition corresponding with described a pair of plunger push rod (6), push away liquid, stable fluid flow is provided.
2. liquid chromatograph constant flow pump as claimed in claim 1 is characterized in that:
Also comprise supporting worm screw (11), worm gear (12), described worm screw (11) is driven by belt pulley (9) and rotates, worm gear (12) rotates under the drive of worm screw (11), described worm gear (12) is connected with worm-wheel shaft (14), and described worm-wheel shaft (14) is connected with the axle center of described end cam (15).
3. liquid chromatograph constant flow pump as claimed in claim 1 is characterized in that: described worm-wheel shaft (14) is provided with corresponding with it pair of bearings (13).
4. liquid chromatograph constant flow pump as claimed in claim 1, it is characterized in that: described belt pulley (9) is connected with the output shaft of motor (8), and it drives rotation by motor (8), described motor (8).
5. liquid chromatogram constant flow pump as claimed in claim 4, it is characterized in that: described motor (8) is stepper motor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2013100645295A CN103104432A (en) | 2013-02-28 | 2013-02-28 | Liquid chromatograph constant flow pump |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2013100645295A CN103104432A (en) | 2013-02-28 | 2013-02-28 | Liquid chromatograph constant flow pump |
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| CN103104432A true CN103104432A (en) | 2013-05-15 |
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| CN2013100645295A Pending CN103104432A (en) | 2013-02-28 | 2013-02-28 | Liquid chromatograph constant flow pump |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104952350A (en) * | 2015-06-29 | 2015-09-30 | 欧世盛（北京）科技有限公司 | High-pressure infusion pump in HPLC (high performance liquid chromatograph) for teaching |
| CN105126720A (en) * | 2015-08-27 | 2015-12-09 | 上海菲立生物科技有限公司 | Constant flow pump micro-channel reaction unit device |
| CN105443347A (en) * | 2015-12-31 | 2016-03-30 | 四川奥博生物医学电子有限公司 | High-pressure pump improved structure |
| CN108170173A (en) * | 2017-12-26 | 2018-06-15 | 迈克医疗电子有限公司 | Flow control methods and device, analytical instrument and computer readable storage medium |
| CN109826772A (en) * | 2019-04-03 | 2019-05-31 | 四川轻化工大学 | A kind of continuously flowing syringe pump system and its control method |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104952350A (en) * | 2015-06-29 | 2015-09-30 | 欧世盛（北京）科技有限公司 | High-pressure infusion pump in HPLC (high performance liquid chromatograph) for teaching |
| CN105126720A (en) * | 2015-08-27 | 2015-12-09 | 上海菲立生物科技有限公司 | Constant flow pump micro-channel reaction unit device |
| CN105126720B (en) * | 2015-08-27 | 2017-01-11 | 上海菲立生物科技有限公司 | Constant flow pump micro-channel reaction unit device |
| CN105443347A (en) * | 2015-12-31 | 2016-03-30 | 四川奥博生物医学电子有限公司 | High-pressure pump improved structure |
| CN108170173A (en) * | 2017-12-26 | 2018-06-15 | 迈克医疗电子有限公司 | Flow control methods and device, analytical instrument and computer readable storage medium |
| CN109826772A (en) * | 2019-04-03 | 2019-05-31 | 四川轻化工大学 | A kind of continuously flowing syringe pump system and its control method |
| CN109826772B (en) * | 2019-04-03 | 2024-05-28 | 四川轻化工大学 | Continuous flow injection pump system and control method thereof |
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Application publication date: 20130515 |