CN103102335A - Method for producing crude sodium L-ascorbate by recovering crude vitamin C mother liquor - Google Patents
Method for producing crude sodium L-ascorbate by recovering crude vitamin C mother liquor Download PDFInfo
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- CN103102335A CN103102335A CN2012104567002A CN201210456700A CN103102335A CN 103102335 A CN103102335 A CN 103102335A CN 2012104567002 A CN2012104567002 A CN 2012104567002A CN 201210456700 A CN201210456700 A CN 201210456700A CN 103102335 A CN103102335 A CN 103102335A
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- esterification reaction
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Abstract
The invention discloses a method for producing crude sodium L-ascorbate by recovering crude vitamin C mother liquor. The method comprises the steps of: destaining crude vitamin C mother liquor through a macroporous adsorption resin, concentrating, crystallizing and centrifuging a destaining solution to obtain a crude vitamin C mother liquor recovered product, crushing and drying the mother liquor recovered product through a micro powder drying machine, performing esterification reaction with methanol, controlling the burdening ratio of mother liquor recovered product (weight) to methanol (volume) in the esterification reaction of 1: 7, reacting for 4 hours, wherein the esterification reaction temperature at the first hour is 68 DEG C, the esterification reaction temperature at the second hour is 60 DEG C, the esterification reaction temperature at the third hour is 55 DEG C and the esterification reaction temperature at the fourth hour is 50 DEG C, adding sodium bicarbonate with stoichiometric amount to perform conversion reaction to obtain intermediate crude sodium L-ascorbate, and then changing over to the production process of normal vitamin C. The production yield and quality of the crude sodium L-ascorbate are improved, the problem of the accumulation of a mother liquor recovered product is solved, and the production process is simplified.
Description
Technical field
The present invention relates to the Progresses of Vitamin C Productive Technology field, relate in particular to a kind of method of crude vitamin C mother liquor remanufacture crude vitamin C sodium.
Background technology:
In the crude product vitamin C production process, contain the 2-KLG of more amount in the mother liquor after the separation crude vitamin C, the conventional processing mode is that direct processing of mother liquor is recycled product, and raw material reenters production process by certain ratio proportioning.The long-time storage that may cause the mother liquor recovery article causes Quality Down, thereby affects production of vitamin C yield and quality product.
Summary of the invention:
The purpose of this invention is to provide a kind of method with crude vitamin C mother liquor remanufacture crude vitamin C sodium, can improve production yield and the quality of crude product vitamin C sodium, solved the accumulation problems of mother liquor recovery article, simplified production process.
the present invention is achieved in that the method for crude vitamin C mother liquor remanufacture crude vitamin C sodium, it is characterized in that comprising step: the crude product vitamin C mother liquor is first by a kind of macroporous adsorbent resin decolouring, the centrifugal rear acquisition crude vitamin C mother liquor recovery article of destainer condensing crystal, after the mother liquor recovery article is pulverized oven dry through micron dryer, carry out esterification with methyl alcohol again, esterification adopts high methanol than low temperature esterification technique, controlling the esterification ratio of components is: mother liquor recovery article (weight): methyl alcohol (volume)=1:7, reacted 4 hours, controlled 68 ℃ of esterification reaction temperatures in first hour, controlled 60 ℃ of esterification reaction temperatures in second hour, controlled 55 ℃ of esterification reaction temperatures on the 3rd hour, controlled 50 ℃ of esterification reaction temperatures on the 4th hour.Add again the sodium bicarbonate of stoichiometric quantity to carry out conversion reaction, obtain intermediate crude vitamin C sodium, change the production process of well-balanced vitamin C over to.
The present invention has improved production yield and the quality of crude product vitamin C sodium, has solved the accumulation problems of mother liquor recovery article, has simplified production process.
Embodiment
the method of crude vitamin C mother liquor remanufacture crude vitamin C sodium, it is characterized in that comprising step: the crude product vitamin C mother liquor is first by a kind of macroporous adsorbent resin decolouring, the centrifugal rear acquisition crude vitamin C mother liquor recovery article of destainer condensing crystal, after the mother liquor recovery article is pulverized oven dry through micron dryer, carry out esterification with methyl alcohol again, esterification adopts high methanol than low temperature esterification technique, controlling the esterification ratio of components is: mother liquor recovery article (weight): methyl alcohol (volume)=1:7, reacted 4 hours, controlled 68 ℃ of esterification reaction temperatures in first hour, controlled 60 ℃ of esterification reaction temperatures in second hour, controlled 55 ℃ of esterification reaction temperatures on the 3rd hour, controlled 50 ℃ of esterification reaction temperatures on the 4th hour.Add again the sodium bicarbonate of stoichiometric quantity to carry out conversion reaction, obtain intermediate crude vitamin C sodium, change the production process of well-balanced vitamin C over to.
Further illustrate by the following examples the present invention, but not as limitation of the present invention.
Embodiment
The crude product vitamin C mother liquor, after the macroporous resin decolouring, carry out condensing crystal, isolate the mother liquor recovery article, carry out esterification after mother liquor recovery article process micro mist drying, 1500kg mother liquor recovery article adds 10500L methyl alcohol, carries out esterification 4 hours, then after adding the sodium bicarbonate of 750kg to carry out conversion reaction, the intermediate sodium ascorbate that obtains is taken a sample to check, and its color and luster is yellowish, and after oven dry, content reaches more than 92%.
The invention is not restricted to these disclosed embodiment; the present invention is with the described scope of soverlay technique scheme; and the various distortion of claim scope and equivalence variation; under the prerequisite that does not depart from technical solution of the present invention, any modification that those skilled in the art made for the present invention easily realize or improvement all belong to the present invention's scope required for protection.
Claims (1)
1. the method for crude vitamin C mother liquor remanufacture crude vitamin C sodium, it is characterized in that comprising step: the crude product vitamin C mother liquor is first by a kind of macroporous adsorbent resin decolouring, the centrifugal rear acquisition crude vitamin C mother liquor recovery article of destainer condensing crystal, after the mother liquor recovery article is pulverized oven dry through micron dryer, carry out esterification with methyl alcohol again, esterification adopts high methanol than low temperature esterification technique, controlling the esterification ratio of components is: mother liquor recovery article (weight): methyl alcohol (volume)=1:7, reacted 4 hours, controlled 68 ℃ of esterification reaction temperatures in first hour, controlled 60 ℃ of esterification reaction temperatures in second hour, controlled 55 ℃ of esterification reaction temperatures on the 3rd hour, controlled 50 ℃ of esterification reaction temperatures on the 4th hour, add again the sodium bicarbonate of stoichiometric quantity to carry out conversion reaction, obtain intermediate crude vitamin C sodium, change the production process of well-balanced vitamin C over to.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104567002A CN103102335A (en) | 2012-11-15 | 2012-11-15 | Method for producing crude sodium L-ascorbate by recovering crude vitamin C mother liquor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012104567002A CN103102335A (en) | 2012-11-15 | 2012-11-15 | Method for producing crude sodium L-ascorbate by recovering crude vitamin C mother liquor |
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| Publication Number | Publication Date |
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| CN103102335A true CN103102335A (en) | 2013-05-15 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2012104567002A Pending CN103102335A (en) | 2012-11-15 | 2012-11-15 | Method for producing crude sodium L-ascorbate by recovering crude vitamin C mother liquor |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106831672A (en) * | 2016-12-30 | 2017-06-13 | 安徽泰格生物技术股份有限公司 | A kind of decoloration treatment method of vitamine C sodium solution |
| CN111018814A (en) * | 2019-12-06 | 2020-04-17 | 石药集团维生药业（石家庄）有限公司 | Method for recycling vitamin C secondary mother liquor |
| CN112876437A (en) * | 2021-01-22 | 2021-06-01 | 无锡绿色分离应用技术研究所有限公司 | Method for extracting vitamin C by using macroporous chelate resin |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5128487A (en) * | 1989-06-26 | 1992-07-07 | Enco Engineering Chur Ag | Process for the production of sodium or potassium l-ascorbate |
| CN101550118A (en) * | 2009-05-22 | 2009-10-07 | 徐建涛 | Synthetic process for vitamin C sodium salts |
| CN101735183A (en) * | 2010-01-26 | 2010-06-16 | 河北维尔康制药有限公司 | Method for synthesizing vitamin C sodium salt |
-
2012
- 2012-11-15 CN CN2012104567002A patent/CN103102335A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5128487A (en) * | 1989-06-26 | 1992-07-07 | Enco Engineering Chur Ag | Process for the production of sodium or potassium l-ascorbate |
| CN101550118A (en) * | 2009-05-22 | 2009-10-07 | 徐建涛 | Synthetic process for vitamin C sodium salts |
| CN101735183A (en) * | 2010-01-26 | 2010-06-16 | 河北维尔康制药有限公司 | Method for synthesizing vitamin C sodium salt |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106831672A (en) * | 2016-12-30 | 2017-06-13 | 安徽泰格生物技术股份有限公司 | A kind of decoloration treatment method of vitamine C sodium solution |
| CN111018814A (en) * | 2019-12-06 | 2020-04-17 | 石药集团维生药业（石家庄）有限公司 | Method for recycling vitamin C secondary mother liquor |
| CN111018814B (en) * | 2019-12-06 | 2022-11-08 | 石药集团维生药业（石家庄）有限公司 | Method for recycling vitamin C secondary mother liquor |
| CN112876437A (en) * | 2021-01-22 | 2021-06-01 | 无锡绿色分离应用技术研究所有限公司 | Method for extracting vitamin C by using macroporous chelate resin |
| CN112876437B (en) * | 2021-01-22 | 2023-10-24 | 无锡绿色分离应用技术研究所有限公司 | Method for extracting vitamin C by using macroporous chelate resin |
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Application publication date: 20130515 |